Jacques Simard

Threshold-Based Overlap of Breast Cancer High-Risk Classification Using Family History, Polygenic Risk Scores, and Traditional Risk Models in 180,398 Womenpublié le 2025-11

Evaluating the performance of the Breast and Ovarian Analysis of Disease Incidence Algorithm model in predicting 10-year breast cancer risks in UK Biobankpublié le 2025-05-01

Barriers and Facilitators to Delivering Multifactorial Risk Assessment and Communication for Personalized Breast Cancer Screening: A Qualitative Study Exploring Implementation in Canadapublié le 2025-03

Evaluating Real World Health System Resource Utilization and Costs for a Risk-Based Breast Cancer Screening Approach in the Canadian PERSPECTIVE Integration and Implementation Projectpublié le 2024-09-18

Implementing Multifactorial Risk Assessment with Polygenic Risk Scores for Personalized Breast Cancer Screening in the Population Setting: Challenges and Opportunitiespublié le 2024-05

A Systematic Review and Critical Assessment of Breast Cancer Risk Prediction Tools Incorporating a Polygenic Risk Score for the General Populationpublié le 2023-11-12

Canadian Healthcare Professionals’ Views and Attitudes toward Risk-Stratified Breast Cancer Screeningpublié le 2023-06

Regulating cancer risk prediction: legal considerations and stakeholder perspectives on the Canadian contextpublié le 2023-06-26

Contralateral breast cancer risk in irradiated breast cancer patients with a germline-BRCA1/2 pathogenic variantpublié le 2023-06-23

Associations of height, body mass index, and weight gain with breast cancer risk in carriers of a pathogenic variant in BRCA1 or BRCA2: the BRCA1 and BRCA2 Cohort Consortiumpublié le 2023-06-20

Genome-wide analyses characterize shared heritability among cancers and identify novel cancer susceptibility regions.publié le 2023-06-01

Functional and clinical characterization of variants of uncertain significance identifies a hotspot for inactivating missense variants in RAD51C.publié le 2023-05-30

Perceptions and Usability of PREVENTION: A Breast Cancer Risk Assessment e-Platformpublié le 2023-05-18

Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2.publié le 2023-04-19

Incorporating Alternative Polygenic Risk Scores into the BOADICEA Breast Cancer Risk Prediction Model.publié le 2023-03-01

Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry. publié le 2023-01-26

Women’s perceptions of PERSPECTIVE: a breast cancer risk stratification e-platformpublié le 2022-12

Genome- and transcriptome-wide association studies of 386,000 Asian and European-ancestry women provide new insights into breast cancer genetics.publié le 2022-11-09

Using Real-World Data to Determine Health System Costs of Ontario Women Screened for Breast Cancerpublié le 2022-10-31

Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers.publié le 2022-10-06

Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study.publié le 2022-09-26

Enhancing the BOADICEA cancer risk prediction model to incorporate new data on RAD51C, RAD51D, BARD1 updates to tumour pathology and cancer incidence.publié le 2022-09-26

Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study.publié le 2022-09-06

Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestrypublié le 2022-07

Gynecologic Cancer Risk and Genetics: Informing an Ideal Model of Gynecologic Cancer Preventionpublié le 2022-06

A genome-wide gene-based gene-environment interaction study of breast cancer in more than 90,000 women.publié le 2022-04-08

Polygenic risk modeling for prediction of epithelial ovarian cancer riskpublié le 2022-03

Rare germline copy number variants (CNVs) and breast cancer risk.publié le 2022-01-18