Vous utilisez un navigateur obsolète ce qui augmente les risques pour votre ordinateur et nuit à la navigation.
Veuillez mettre à jour votre navigateur afin d'optimiser votre expérience.
An evidence-based preclinical framework for the development of antimicrobial therapeutics in cystic fibrosis (PIPE-CF)- Cystic Fibrosis Trust, University of Liverpool, co-chercheur - 2021-10-01 au 2024-03-31
A Smart Surveillance Strategy for Carbapenem-resistant Pseudomonas aeruginosa - SAMPAN- Instituts de recherche en santé du Canada - Joint Programming Initiative on Antimicrobial Resistance JPIAMR, Université Érasme de Rotterdam, co-chercheur - 2019-10-01 au 2024-03-01
SENTINEL : Stopping Enteric Illnesses Early- Génome Canada, Ministère de l'agriculture, des pêcheries et de l'alimentation, Génome Québec - Programme de partenariats pour les applications de la génomique (PPAG), University of Guelph, co-chercheur - 2020-07-01 au 2023-06-30
SENTINEL : Stopping Enteric Illnesses Early - Activité 3- Génome Canada, Génome Québec - Programme de partenariats pour les applications de la génomique (PPAG), University of Guelph, co-chercheur - 2020-07-01 au 2023-06-30
SENTINEL : Stopping Enteric Illnesses Early - Activité 1- Génome Québec, Génome Canada - Programme de partenariats pour les applications de la génomique (PPAG), University of Guelph, co-chercheur - 2020-07-01 au 2023-06-30
Diagnosing the onset of severe Covid-19 disease- Instituts de recherche en santé du Canada - Subvention de fonctionnement : Possibilité de financement pour une intervention de recherche rapide contre la COVID-19, University of British Columbia, co-chercheur - 2020-06-01 au 2023-03-31
BioSurveillance of Alien Forest Enemies (bioSAFE)- Génome Québec, Genome British Columbia, Génome Canada - Les ressources naturelles et l'environnement: les solutions génomiques aux défis sectoriels, University of British Columbia, co-chercheur - 2016-10-01 au 2022-03-31
Gypsy moth genome annotation and comparison- United States Department of Agriculture, chercheur principal - 2020-09-23 au 2021-09-22
A syst-Omics approach to ensuring food safety and reducing the economic burden of salmonellosis- Génome Québec, Génome Canada, Genome British Columbia - La génomique pour nourrir l'avenir, McGill University, co-chercheur - 2015-04-01 au 2021-03-31
BioPrintGenomics: Next Generation 3D Bioprinting of Human lung Tissues- Fonds de recherche du Québec - Santé - Réseaux thématiques de recherche, chercheur principal - 2020-01-01 au 2020-12-31
Mission AND-Eau : Projet de science citoyenne- Génome Québec, chercheur principal - 2019-10-07 au 2020-12-15
...
En voir plus
Publications
Mutational spectra analysis reveals bacterial niche and transmission routes, Christopher Ruis, Aaron Weimann, Gerry Tonkin-Hill, Arun Prasad Pandurangan, Marta Matuszewska, Gemma G. R. Murray, Roger C. Lévesque, Tom L. Blundell, R. Andres Floto, Julian Parkhill, 2022, 10.1101/2022.07.13.499881
The Spruce Budworm Genome: Reconstructing the Evolutionary History of Antifreeze Proteins., , Genome biology and evolution, 2022, 10.1093/gbe/evac087
Liverpool Epidemic Strain Isolates of Pseudomonas aeruginosa Display High Levels of Antimicrobial Resistance during Both Planktonic and Biofilm Growth., , Microbiology spectrum, 2022, 10.1128/spectrum.01024-22
Draft Genome Sequences of Two Clostridium botulinum Group II Strains Carrying Phage-Like Plasmids., , Microbiology resource announcements, 2022, 10.1128/mra.00091-22
Application of a High-Throughput Targeted Sequence AmpliSeq Procedure to Assess the Presence and Variants of Virulence Genes in Salmonella, Ruimin Gao, Hongsheng Huang, Jérémie Hamel, Roger C. Levesque, Lawrence D. Goodridge, Dele Ogunremi, Microorganisms, 2022, 10.3390/microorganisms10020369
An Organ System-Based Synopsis of Pseudomonas aeruginosa Virulence., , Virulence, 2021, 10.1080/21505594.2021.1926408
Genome evolution drives transcriptomic and phenotypic adaptation in Pseudomonas aeruginosa during 20 years of infection, Samuel J.T. Wardell, Jeff Gauthier, Lois W. Martin, Marianne Potvin, Ben Brockway, Roger C. Levesque, Iain L. Lamont, Microbial Genomics, 2021, 10.1099/mgen.0.000681
Single nucleotide variants in Pseudomonas aeruginosa populations from sputum correlate with baseline lung function and predict disease progression in individuals with cystic fibrosis, Morteza M. Saber, Jannik Donner, Inès Levade, Nicole Acosta, Michael D. Parkins, Brian Boyle, Roger Levesque, Dao Nguyen, B. Jesse Shapiro, 2021, 10.1101/2021.10.04.21264421
Combined use of Oxford Nanopore and Illumina sequencing yields insights into soybean structural variation biology, Marc-André Lemay, Jonas A. Sibbesen, Davoud Torkamaneh, Jérémie Hamel, Roger C. Levesque, François Belzile, 2021, 10.1101/2021.08.26.457816
Design and Evaluation of New Quinazolin-4(3H)-one Derived PqsR Antagonists as Quorum Sensing Quenchers in Pseudomonas aeruginosa., , ACS infectious diseases, 2021, 10.1021/acsinfecdis.1c00175
Salmonella enterica subsp. enterica virulence potential can be linked to higher survival within a dynamic in vitro human gastrointestinal model., , Food microbiology, 2021, 10.1016/j.fm.2021.103877
Gene-Gene Interactions Dictate Ciprofloxacin Resistance in Pseudomonas aeruginosa and Facilitate Prediction of Resistance Phenotype from Genome Sequence Data., , Antimicrobial agents and chemotherapy, 2021, 10.1128/aac.02696-20
Novel antimicrobial anionic cecropins from the spruce budworm feature a poly-L-aspartic acid C-terminus., , Proteins, 2021, 10.1002/prot.26142
Transmission, adaptation and geographical spread of the Pseudomonas aeruginosa Liverpool epidemic strain., , Microbial genomics, 2021, 10.1099/mgen.0.000511
Complete Genome Sequence of a Pseudomonas Species Isolated from Tailings Pond Water in Alberta, Canada., , Microbiology resource announcements, 2021, 10.1128/mra.01174-20
Sequencing, assembly and annotation of the whole-insect genome of Lymantria dispar dispar, the European gypsy moth, Sparks, M.E., Hebert, F.O., Johnston, J.S., Hamelin, R.C., Cusson, M., Levesque, R.C., Gundersen-Rindal, D.E., G3: Genes, Genomes, Genetics, 2021, 10.1093/g3journal/jkab150
The Pseudomonas aeruginosa whole genome sequence: A 20th anniversary celebration, Brinkman, F.S.L., Winsor, G.L., Done, R.E., Filloux, A., Francis, V.I., Goldberg, J.B., Greenberg, E.P., Han, K., Hancock, R.E.W., Haney, C.H., Häußler, S., Klockgether, J., Lamont, I.L., Levesque, R.C., Lory, S., Nikel, P.I., Porter, S.L., Scurlock, M.W., Schweizer, H.P., Tümmler, B., Wang, M., Welch, M., Advances in Microbial Physiology, 2021, 10.1016/bs.ampbs.2021.07.001
Bacteriophage-Induced Lipopolysaccharide Mutations in Escherichia coli Lead to Hypersensitivity to Food Grade Surfactant Sodium Dodecyl Sulfate, , Antibiotics, 2020, 10.3390/antibiotics9090552
The Salmonella enterica Plasmidome as a Reservoir of Antibiotic Resistance., , Microorganisms, 2020, 10.3390/microorganisms8071016
Combining Whole-Genome Sequencing and Multimodel Phenotyping To Identify Genetic Predictors of Salmonella Virulence., , mSphere, 2020, 10.1128/msphere.00293-20
Phenomic and genomic approaches to studying the inhibition of multiresistant Salmonella enterica by microcin J25., , Environmental microbiology, 2020, 10.1111/1462-2920.15045
Structural insights into the putative bacterial acetylcholinesterase ChoE and its substrate inhibition mechanism., , The Journal of biological chemistry, 2020, 10.1074/jbc.ra119.011809
Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa., , Frontiers in chemistry, 2020, 10.3389/fchem.2020.00204
A New Whole Genome Culture-Independent Diagnostic Test (WG-CIDT) for Rapid Detection of Salmonella in Lettuce., , Frontiers in microbiology, 2020, 10.3389/fmicb.2020.00602
Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic-Pharmacodynamic Modeling for Evaluation of Treatments against Chronic Pseudomonas aeruginosa Lung Infections., , Molecular pharmaceutics, 2020, 10.1021/acs.molpharmaceut.9b00968
A megaplasmid family driving dissemination of multidrug resistance in Pseudomonas., , Nature communications, 2020, 10.1038/s41467-020-15081-7
Bacteriophage-Insensitive Mutants of Antimicrobial-Resistant Salmonella Enterica are Altered in their Tetracycline Resistance and Virulence in Caco-2 Intestinal Cells., , International journal of molecular sciences, 2020, 10.3390/ijms21051883
Continent-wide population genomic structure and phylogeography of North America's most destructive conifer defoliator, the spruce budworm (Choristoneura fumiferana)., , Ecology and evolution, 2020, 10.1002/ece3.5950
Comparative genomic analysis of 142 bacteriophages infecting Salmonella enterica subsp. enterica, Gao, R., Naushad, S., Moineau, S., Levesque, R., Goodridge, L., Ogunremi, D., BMC Genomics, 2020, 10.1186/s12864-020-6765-z
Reassessment of the status of Lymantria albescens and Lymantria postalba (Lepidoptera: Erebidae: Lymantriinae) as distinct ‘Asian gypsy moth’ species, using both mitochondrial and nuclear sequence data, Djoumad, A., Nisole, A., Stewart, D., Holden, D., Zahiri, R., Inoue, M.N., Martemyanov, V.V., Levesque, R.C., Hamelin, R.C., Cusson, M., Systematic Entomology, 2020, 10.1111/syen.12410
Reuse of voucher specimens provides insights into the genomic associations and taxonomic value of wing colour and genitalic differences in a pest group (Lepidoptera: Tortricidae: Choristoneura), French, R.L.K., Lebunasin, P.N.A., Brunet, B.M.T., Lumley, L.M., Cusson, M., Levesque, R.C., Sperling, F.A.H., Systematic Entomology, 2020, 10.1111/syen.12416
Similar yet different: Phylogenomic analysis to delineate Salmonella and Citrobacter species boundaries, Pilar, A.V.C., Petronella, N., Dussault, F.M., Verster, A.J., Bekal, S., Levesque, R.C., Goodridge, L., Tamber, S., BMC Genomics, 2020, 10.1186/s12864-020-06780-y
Inactivation of Salmonella enterica on post-harvest cantaloupe and lettuce by a lytic bacteriophage cocktail., , Current research in food science, 2019, 10.1016/j.crfs.2019.11.004
Expansion of LINEs and species-specific DNA repeats drives genome expansion in Asian Gypsy Moths., , Scientific reports, 2019, 10.1038/s41598-019-52840-z
Diversity and Host Specificity Revealed by Biological Characterization and Whole Genome Sequencing of Bacteriophages Infecting Salmonella enterica., , Viruses, 2019, 10.3390/v11090854
Temporal variation in spatial genetic structure during population outbreaks: Distinguishing among different potential drivers of spatial synchrony., , Evolutionary applications, 2019, 10.1111/eva.12852
Culture-Dependent Bioprospecting of Bacterial Isolates From the Canadian High Arctic Displaying Antibacterial Activity., , Frontiers in microbiology, 2019, 10.3389/fmicb.2019.01836
Reservoirs of resistance: polymyxin resistance in veterinary-associated companion animal isolates of Pseudomonas aeruginosa., , The Veterinary record, 2019, 10.1136/vr.105075
Fate of 43 Salmonella Strains on Lettuce and Tomato Seedlings., , Journal of food protection, 2019, 10.4315/0362-028x.jfp-18-435
The Pseudomonas aeruginosa Population among Cystic Fibrosis Patients in Quebec, Canada: a Disease Hot Spot without Known Epidemic Isolates., , Journal of clinical microbiology, 2019, 10.1128/jcm.02019-18
Major Release of 161 Whole-Genome Sequences from the International Pseudomonas Consortium Database., , Microbiology resource announcements, 2019, 10.1128/mra.00013-19
A megaplasmid family responsible for dissemination of multidrug resistance in Pseudomonas, Cazares, A., Moore, M.P., Grimes, M., Emond-Rhéault, J.-G., Wright, L.L., Pongchaikul, P., Santanirand, P., Levesque, R.C., Fothergill, J.L., Winstanley, C., bioRxiv, 2019, 10.1101/630780
A needle in a haystack: a multigene TaqMan assay for the detection of Asian gypsy moths in bulk pheromone trap samples, Stewart, D., Nisole, A., Djoumad, A., Zahiri, R., Lamarche, J., Levesque, R.C., Hamelin, R.C., Cusson, M., Biological Invasions, 2019, 10.1007/s10530-019-01943-9
Species interactions and distinct microbial communities in high Arctic permafrost affected cryosols are associated with the CH4 and CO2 gas fluxes, Altshuler, I., Hamel, J., Turney, S., Magnuson, E., Lévesque, R., Greer, C.W., Whyte, L.G., Environmental Microbiology, 2019, 10.1111/1462-2920.14715
The Pseudomonas aeruginosa Pan-Genome Provides New Insights on Its Population Structure, Horizontal Gene Transfer, and Pathogenicity., , Genome biology and evolution, 2019, 10.1093/gbe/evy259
Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection., , Journal of pharmaceutical sciences, 2018, 10.1016/j.xphs.2018.09.017
Direct In Vivo Microbial Transcriptomics During Infection., , Trends in microbiology, 2018, 10.1016/j.tim.2018.07.002
Insights into the Structure of the Spruce Budworm (Choristoneura fumiferana) Genome, as Revealed by Molecular Cytogenetic Analyses and a High-Density Linkage Map., , G3 (Bethesda, Md.), 2018, 10.1534/g3.118.200263
A new approach to study attached biofilms and floating communities from Pseudomonas aeruginosa strains of various origins reveals diverse effects of divalent ions., , FEMS microbiology letters, 2018, 10.1093/femsle/fny155
Genomic characterisation of an international Pseudomonas aeruginosa reference panel indicates that the two major groups draw upon distinct mobile gene pools., , FEMS microbiology letters, 2018, 10.1093/femsle/fny120
Salmonella enterica Prophage Sequence Profiles Reflect Genome Diversity and Can Be Used for High Discrimination Subtyping., , Frontiers in microbiology, 2018, 10.3389/fmicb.2018.00836
A multi-host approach to identify a transposon mutant of Pseudomonas aeruginosa LESB58 lacking full virulence., , BMC research notes, 2018, 10.1186/s13104-018-3308-7
Exacerbation induces a microbiota shift in sputa of COPD patients., , PloS one, 2018, 10.1371/journal.pone.0194355
Convergent herbivory on conifers by Choristoneura moths after boreal forest formation., , Molecular phylogenetics and evolution, 2018, 10.1016/j.ympev.2018.01.013
Assessing the potential of genotyping-by-sequencing-derived single nucleotide polymorphisms to identify the geographic origins of intercepted gypsy moth (Lymantria dispar) specimens: A proof-of-concept study, Picq, S., Keena, M., Havill, N., Stewart, D., Pouliot, E., Boyle, B., Levesque, R.C., Hamelin, R.C., Cusson, M., Evolutionary Applications, 2018, 10.1111/eva.12559
For the Safety of Fresh Produce: Regulatory Considerations for Canada on the Use of Whole Genome Sequencing to Subtype Salmonella, Ngueng Feze, I., Dalpé, G., Song, L., Farber, J., Goodridge, L., Levesque, R.C., Joly, Y., Frontiers in Sustainable Food Systems, 2018, 10.3389/fsufs.2018.00021
Novel anionic cecropins from the spruce budworm feature a poly-L-aspartic acid C-terminus, Maaroufi, H., Cusson, M., Levesque, R.C., bioRxiv, 2018, 10.1101/307702
Prophage induction reduces Shiga toxin producing Escherichia coli (STEC) and Salmonella enterica on tomatoes and spinach: A model study, Cadieux, B., Colavecchio, A., Jeukens, J., Freschi, L., Emond-Rheault, J.-G., Kukavica-Ibrulj, I., Levesque, R.C., Bekal, S., Chandler, J.C., Coleman, S.M., Bisha, B., Goodridge, L.D., Food Control, 2018, 10.1016/j.foodcont.2018.02.001
Characterization of Four Novel Bacteriophages Isolated from British Columbia for Control of Non-typhoidal Salmonella in Vitro and on Sprouting Alfalfa Seeds., , Frontiers in microbiology, 2017, 10.3389/fmicb.2017.02193
Distinct sources of gene flow produce contrasting population genetic dynamics at different range boundaries of a Choristoneura budworm., , Molecular ecology, 2017, 10.1111/mec.14386
Whole-Genome Sequencing of Lactobacillus Species from Two Commercial Probiotic Products., , Genome announcements, 2017, 10.1128/genomea.01279-17
Comparative analysis of mitochondrial genomes of geographic variants of the gypsy moth, Lymantria dispar, reveals a previously undescribed genotypic entity., , Scientific reports, 2017, 10.1038/s41598-017-14530-6
Comparative genomics of a drug-resistant Pseudomonas aeruginosa panel and the challenges of antimicrobial resistance prediction from genomes., , FEMS microbiology letters, 2017, 10.1093/femsle/fnx161
Genomic characterisation of environmental Pseudomonas aeruginosa isolated from dental unit waterlines revealed the insertion sequence ISPa11 as a chaotropic element., , FEMS microbiology ecology, 2017, 10.1093/femsec/fix106
Prophage Integrase Typing Is a Useful Indicator of Genomic Diversity in Salmonella enterica., , Frontiers in microbiology, 2017, 10.3389/fmicb.2017.01283
A Syst-OMICS Approach to Ensuring Food Safety and Reducing the Economic Burden of Salmonellosis., , Frontiers in microbiology, 2017, 10.3389/fmicb.2017.00996
Genomics of antibiotic-resistance prediction in Pseudomonas aeruginosa., , Annals of the New York Academy of Sciences, 2017, 10.1111/nyas.13358
Complete Genome Sequences of Two Phage-Like Plasmids Carrying the CTX-M-15 Extended-Spectrum β-Lactamase Gene., , Genome announcements, 2017, 10.1128/genomea.00102-17
A Pan-Genomic Approach to Understand the Basis of Host Adaptation in Achromobacter., , Genome biology and evolution, 2017, 10.1093/gbe/evx061
AnCo3, a new member of the emerging family of phage-like plasmids, Colavecchio, A., Jeukens, J., Freschi, L., Edmond Rheault, J.-G., Kukavica-Ibrulj, I., Levesque, R., Goodridge, L., Genome Announcements, 2017, 10.1128/genomeA.00110-17
Genome-wide SNPs resolve phylogenetic relationships in the North American spruce budworm (Choristoneura fumiferana) species complex, Dupuis, J.R., Brunet, B.M.T., Bird, H.M., Lumley, L.M., Fagua, G., Boyle, B., Levesque, R., Cusson, M., Powell, J.A., Sperling, F.A.H., Molecular Phylogenetics and Evolution, 2017, 10.1016/j.ympev.2017.04.001
Two's company, three's a crowd: new insights on spruce budworm species boundaries using genotyping-by-sequencing in an integrative species assessment (Lepidoptera: Tortricidae), Brunet, B.M.T., Blackburn, G.S., Muirhead, K., Lumley, L.M., Boyle, B., LÉVESQUE, R.C., Cusson, M., Sperling, F.A.H., Systematic Entomology, 2017, 10.1111/syen.12211
A Multi-Species TaqMan PCR Assay for the Identification of Asian Gypsy Moths (Lymantria spp.) and Other Invasive Lymantriines of Biosecurity Concern to North America., , PloS one, 2016, 10.1371/journal.pone.0160878
Cyclic peptides identified by phage display are competitive inhibitors of the tRNA-dependent amidotransferase of Helicobacter pylori., , Peptides, 2016, 10.1016/j.peptides.2016.03.001
Increasing genomic diversity and evidence of constrained lifestyle evolution due to insertion sequences in Aeromonas salmonicida., , BMC genomics, 2016, 10.1186/s12864-016-2381-3
Molybdate transporter ModABC is important for Pseudomonas aeruginosa chronic lung infection., , BMC research notes, 2016, 10.1186/s13104-016-1840-x
Genes required for free phage production are essential for pseudomonas aeruginosa chronic lung infections, Lemieux, A.-A., Jeukens, J., Kukavica-Ibrulj, I., Fothergill, J.L., Boyle, B., Laroche, J., Tucker, N.P., Winstanley, C., Levesque, R.C., Journal of Infectious Diseases, 2016, 10.1093/infdis/jiv415
Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium, Freschi, L., Jeukens, J., Kukavica-Ibrulj, I., Boyle, B., Dupont, M.-J., Laroche, J., Larose, S., Maaroufi, H., Fothergill, J.L., Moore, M., Winsor, G.L., Aaron, S.D., Barbeau, J., Bell, S.C., Burns, J.L., Camara, M., Cantin, A., Charette, S.J., Dewar, K., Déziel, É., Grimwood, K., Hancock, R.E.W., Harrison, J.J., Heeb, S., Jelsbak, L., Jia, B., Kenna, D.T., Kidd, T.J., Klockgether, J., Lam, J.S., Lamont, I.L., Lewenza, S., Loman, N., Malouin, F., Manos, J., McArthur, A.G., McKeown, J., Milot, J., Naghra, H., Nguyen, D., Pereira, S.K., Perron, G.G., Pirnay, J.-P., Rainey, P.B., Rousseau, S., Santos, P.M., Stephenson, A., Taylor, V., Turton, J.F., Waglechner, N., Williams, P., Thrane, S.W., Wright, G.D., Brinkman, F.S.L., Tucker, N.P., Tümmler, B., Winstanley, C., Levesque, R.C., Frontiers in Microbiology, 2015, 10.3389/fmicb.2015.01036
Comparative genomics and biological characterization of sequential Pseudomonas aeruginosa isolates from persistent airways infection, Bianconi, I., Jeukens, J., Freschi, L., Alcalá-Franco, B., Facchini, M., Boyle, B., Molinaro, A., Kukavica-Ibrulj, I., Tümmler, B., Levesque, R.C., Bragonzi, A., BMC Genomics, 2015, 10.1186/s12864-015-2276-8
Composition of the spruce budworm (Choristoneura fumiferana) midgut microbiota as affected by rearing conditions, Landry, M., Comeau, A.M., Derome, N., Cusson, M., Levesque, R.C., PLoS ONE, 2015, 10.1371/journal.pone.0144077
Draft genome sequence of triclosan-resistant cystic fibrosis isolate Achromobacter xylosoxidans CF304, Jeukens, J., Freschi, L., Kukavica-Ibrulj, I., Nguyen, D., Levesque, R.C., Genome Announcements, 2015, 10.1128/genomeA.00865-15
Draft genome sequences of two lipopeptide-producing strains of Bacillus methylotrophicus, Jeukens, J., Kukavica-Ibrulj, I., Freschi, L., Jabaji, S., Levesque, R.C., Genome Announcements, 2015, 10.1128/genomeA.01176-15
Essential genes in the infection model of pseudomonas aeruginosa -PCR-based signature-tagged mutagenesis, Kukavica-Ibrulj, I., Levesque, R.C., Methods in Molecular Biology, 2015, 10.1007/978-1-4939-2398-4_7
Functional annotation of the ophiostoma novo-ulmi genome: Insights into the phytopathogenicity of the fungal agent of Dutch elm disease, Comeau, A.M., Dufour, J., Bouvet, G.F., Jacobi, V., Nigg, M., Henrissat, B., Laroche, J., Levesque, R.C., Bernier, L., Genome Biology and Evolution, 2015, 10.1093/gbe/evu281
Glycoside hydrolase family 32 is present in Bacillus subtilis phages, Maaroufi, H., Levesque, R.C., Virology Journal, 2015, 10.1186/s12985-015-0373-6
The widespread multidrug-resistant serotype O12 pseudomonas aeruginosa clone emerged through concomitant horizontal transfer of serotype antigen and antibiotic resistance gene clusters, Thrane, S.W., Taylor, V.L., Freschi, L., Kukavica-Ibrulj, I., Boyle, B., Laroche, J., Pirnay, J.-P., Lévesque, R.C., Lam, J.S., Jelsbaka, L., mBio, 2015, 10.1128/mBio.01396-15
Assessing Pseudomonas aeruginosa virulence and the host response using Murine models of acute and chronic lung infection, Kukavica-Ibrulj, I., Facchini, M., Cigana, C., Levesque, R.C., Bragonzi, A., Methods in Molecular Biology, 2014, 10.1007/978-1-4939-0473-0_58
Comparative genomics of isolates of a Pseudomonas aeruginosa epidemic strain associated with chronic lung infections of cystic fibrosis patients, Jeukens, J., Boyle, B., Kukavica-Ibrulj, I., Ouellet, M.M., Aaron, S.D., Charette, S.J., Fothergill, J.L., Tucker, N.P., Winstanley, C., Levesque, R.C., PLoS ONE, 2014, 10.1371/journal.pone.0087611
Draft genomes of 12 host-adapted and environmental isolates of Pseudomonas aeruginosa and their positions in the core genome phylogeny, Stewart, L., Ford, A., Sangal, V., Jeukens, J., Boyle, B., Kukavica-Ibrulj, I., Caim, S., Crossman, L., Hoskisson, P.A., Levesque, R., Tucker, N.P., Pathogens and Disease, 2014, 10.1111/2049-632X.12107
Requirement of the Pseudomonas aeruginosa CbrA sensor kinase for full virulence in a murine acute lung infection model, Yeung, A.T.Y., Janot, L., Pena, O.M., Neidig, A., Kukavica-Ibrulj, I., Hilchie, A., Levesque, R.C., Overhage, J., Hancock, R.E.W., Infection and Immunity, 2014, 10.1128/IAI.01527-13
Signature-tagged mutagenesis, Kukavica-Ibrulj, I., Levesque, R.C., Methods in Molecular Biology, 2014, 10.1007/978-1-4939-0473-0_41
Strategy for genome sequencing analysis and assembly for comparative genomics of Pseudomonas genomes, Jeukens, J., Boyle, B., Tucker, N.P., Levesque, R.C., Methods in Molecular Biology, 2014, 10.1007/978-1-4939-0473-0_43
The biology of Mur ligases as an antibacterial target, Kouidmi, I., Levesque, R.C., Paradis-Bleau, C., Molecular Microbiology, 2014, 10.1111/mmi.12758
Complete genome sequence of persistent cystic fibrosis isolate Pseudomonas aeruginosa strain RP73, Jeukens, J., Boyle, B., Bianconi, I., Kukavica-Ibrulj, I., Tümmler, B., Bragonzi, A., Levesque, R.C., Genome Announcements, 2013, 10.1128/genomeA.00568-13
Sequencing of the Dutch elm disease fungus genome using the Roche/454 GS-FLX titanium system in a comparison of multiple genomics core facilities, Forgetta, V., Leveque, G., Dias, J., Grove, D., Lyons Jr., R., Genik, S., Wright, C., Singh, S., Peterson, N., Zianni, M., Kieleczawa, J., Steen, R., Perera, A., Bintzler, D., Adams, S., Hintz, W., Jacobi, V., Bernier, L., Levesque, R., Dewar, K., Journal of Biomolecular Techniques, 2013, 10.7171/jbt.12-2401-005
Cell culture tracking by multivariate analysis of raw LCMS data, Michaud, F.-T., Havugimana, P.C., Duchesne, C., Sanschagrin, F., Bernier, A., Levesque, R.C., Garnier, A., Applied Biochemistry and Biotechnology, 2012, 10.1007/s12010-012-9661-4
Complete genome sequences of three Pseudomonas aeruginosa isolates with phenotypes of polymyxin B adaptation and inducible resistance, Boyle, B., Fernandez, L., Laroche, J., Kukavica-Ibrulj, I., Mendes, C.M.F., Hancock, R.W., Levesque, R.C., Journal of Bacteriology, 2012, 10.1128/JB.06246-11
Genomics of Banchine Ichnoviruses: Insights into their relationship to Bracoviruses and Campoplegine Ichnoviruses, Cusson, M., Stoltz, D., Lapointe, R., Béliveau, C., Nisole, A., Volkoff, A.-N., Drezen, J.-M., Maaroufi, H., Levesque, R.C., Parasitoid Viruses: Symbionts and Pathogens, 2012, 10.1016/B978-0-12-384858-1.00006-0
The Lon Protease Is Essential for Full Virulence in Pseudomonas aeruginosa, Breidenstein, E.B.M., Janot, L., Strehmel, J., Fernandez, L., Taylor, P.K., Kukavica-Ibrulj, I., Gellatly, S.L., Levesque, R.C., Overhage, J., Hancock, R.E.W., PLoS ONE, 2012, 10.1371/journal.pone.0049123
BAC library construction, screening and clone sequencing of lake whitefish (Coregonus clupeaformis, Salmonidae) towards the elucidation of adaptive species divergence, Jeukens, J., Boyle, B., Kukavica-Ibrulj, I., St-Cyr, J., Lévesque, R.C., Bernatchez, L., Molecular Ecology Resources, 2011, 10.1111/j.1755-0998.2011.02982.x
Positive signature-tagged mutagenesis in Pseudomonas aeruginosa: Tracking patho-adaptive mutations promoting airways chronic infection, Bianconi, I., Milani, A., Cigana, C., Paroni, M., Levesque, R.C., Bertoni, G., Bragonzi, A., PLoS Pathogens, 2011, 10.1371/journal.ppat.1001270
Biophysical studies of the interactions between the phage φ KZ gp144 lytic transglycosylase and model membranes, Cloutier, I., Paradis-Bleau, C., Giroux, A.-M., Pigeon, X., Arseneault, M., Levesque, R.C., Auger, M., European Biophysics Journal, 2010, 10.1007/s00249-009-0530-1
Characterization of alanine catabolism in Pseudomonas aeruginosa and its importance for proliferation in vivo, Boulette, M.L., Baynham, P.J., Jorth, P.A., Kukavica-Ibrulj, I., Longoria, A., Barrera, K., Levesque, R.C., Whiteley, M., Journal of Bacteriology, 2009, 10.1128/JB.00817-09
Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the liverpool epidemic strain of pseudomonas aeruginosa, Winstanley, C., Langille, M.G.I., Fothergill, J.L., Kukavica-Ibrulj, I., Paradis-Bleau, C., Sanschagrin, F., Thomson, N.R., Winsor, G.L., Quail, M.A., Lennard, N., Bignell, A., Clarke, L., Seeger, K., Saunders, D., Harris, D., Parkhill, J., Hancock, R.E.W., Brinkman, F.S.L., Levesque, R.C., Genome Research, 2009, 10.1101/gr.086082.108
The sensor kinase PhoQ mediates virulence in Pseudomonas aeruginosa, Gooderham, W.J., Gellatly, S.L., Sanschagrin, F., McPhee, J.B., Bains, M., Cosseau, C., Levesque, R.C., Hancock, R.E.W., Microbiology, 2009, 10.1099/mic.0.024554-0
Animal models of chronic lung infection with Pseudomonas aeruginosa: Useful tools for cystic fibrosis studies, Kukavica-Ibrulj, I., Levesque, R.C., Laboratory Animals, 2008, 10.1258/la.2007.06014e
Characterization of tRNA-dependent peptide bond formation by MurM in the synthesis of Streptococcus pneumoniae peptidoglycan, Lloyd, A.J., Gilbey, A.M., Blewett, A.M., De Pascale, G., El Zoeiby, A., Levesque, R.C., Catherwood, A.C., Tomasz, A., Bugg, T.D.H., Roper, D.I., Dowson, C.G., Journal of Biological Chemistry, 2008, 10.1074/jbc.M708105200
Discovery of new MurF inhibitors via pharmacophore modeling and QSAR analysis followed by in-silico screening, Taha, M.O., Atallah, N., Al-Bakri, A.G., Paradis-Bleau, C., Zalloum, H., Younis, K.S., Levesque, R.C., Bioorganic and Medicinal Chemistry, 2008, 10.1016/j.bmc.2007.10.076
Functional genomics PycR, a LysR family transcriptional regulator essential for maintenance of Pseudomonas aeruginosa in the rat lung, Kukavica-Ibrulj, I., Sanschagrin, F., Peterson, A., Whiteley, M., Boyle, B., MacKay, J., Levesque, R.C., Microbiology, 2008, 10.1099/mic.0.2007/011239-0
In vivo growth of Pseudomonas aeruginosa strains PAO1 and PA14 and the hypervirulent strain LESB58 in a rat model of chronic lung infection, Kukavica-Ibrulj, I., Bragonzi, A., Paroni, M., Winstanley, C., Sanschagrin, F., O'Toole, G.A., Levesque, R.C., Journal of Bacteriology, 2008, 10.1128/JB.01572-07
Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF, Paradis-Bleau, C., Lloyd, A., Sanschagrin, F., Clarke, T., Blewett, A., Bugg, T.D.H., Levesque, R.C., BMC Biochemistry, 2008, 10.1186/1471-2091-9-33
Proteomic, microarray, and signature-tagged mutagenesis analyses of anaerobic Pseudomonas aeruginosa at pH 6.5, likely representing chronic, late-stage cystic fibrosis airway conditions, Platt, M.D., Schurr, M.J., Sauer, K., Vazquez, G., Kukavica-Ibrulj, I., Potvin, E., Levesque, R.C., Fedynak, A., Brinkman, F.S.L., Schurr, J., Hwang, S.-H., Lau, G.W., Limbach, P.A., Rowe, J.J., Lieberman, M.A., Barraud, N., Webb, J., Kjelleberg, S., Hunt, D.F., Hassett, D.J., Journal of Bacteriology, 2008, 10.1128/JB.01683-07
Sigma factors in Pseudomonas aeruginosa, Potvin, E., Sanschagrin, F., Levesque, R.C., FEMS Microbiology Reviews, 2008, 10.1111/j.1574-6976.2007.00092.x
Transcription of foreign DNA in Escherichia coli, Warren, R.L., Freeman, J.D., Levesque, R.C., Smailus, D.E., Flibotte, S., Holt, R.A., Genome Research, 2008, 10.1101/gr.080358.108
Essential genes in the infection model of Pseudomonas aeruginosa PCR-based signature-tagged mutagenesis, Sanschagrin, F., Kukavica-Ibrulj, I., Levesque, R.C., Methods in Molecular Biology, 2007
Parallel solid synthesis of inhibitors of the essential cell division FtsZ enzyme as a new potential class of antibacterials, Paradis-Bleau, C., Beaumont, M., Sanschagrin, F., Voyer, N., Levesque, R.C., Bioorganic and Medicinal Chemistry, 2007, 10.1016/j.bmc.2006.11.015
Peptidoglycan lytic activity of the Pseudomonas aeruginosa phage φKZ gp144 lytic transglycosylase, Paradis-Bleau, C., Cloutier, I., Lemieux, L., Sanschagrin, F., Laroche, J., Auger, M., Garnier, A., Levesque, R.C., FEMS Microbiology Letters, 2007, 10.1111/j.1574-6968.2006.00523.x
The flagellum of Pseudomonas aeruginosa is required for resistance to clearance by surfactant protein A, Zhang, S., McCormack, F.X., Levesque, R.C., O'Toole, G.A., Lau, G.W., PLoS ONE, 2007, 10.1371/journal.pone.0000564
1H, 13C, and 15N backbone resonance assignments for PSE-4, a 29.5 kDa class A beta-lactamase from Pseudomonas aeruginosa., Morin, S., Levesque, R.C., Gagné, S.M., Journal of biomolecular NMR, 2006, 10.1007/s10858-005-5343-7
A peptide inhibitor of MurA UDP-N-acetylglucosamine enolpyruvyl transferase: The first committed step in peptidoglycan biosynthesis, Molina-López, J., Sanschagrin, F., Levesque, R.C., Peptides, 2006, 10.1016/j.peptides.2006.08.023
Erratum: 1H, 13C, and 15N backbone resonance assignments for PSE-4, a 29.5 kDa class A β-lactamase from Pseudomonas aeruginosa (Journal of Biomolecular NMR 10.1007/s10858-005-5343-7), Morin, S., Levesque, R.C., Gagné, S.M., Journal of Biomolecular NMR, 2006, 10.1007/s10858-006-9069-y
In vivo functional genomics of pseudomonas: PCR-based signature-tagged mutagenesis, Levesque, R.C., Pseudomonas, 2006, 10.1007/0-387-28881-3_4
Selection of peptide inhibitors against the Pseudomonas aeruginosa MurD cell wall enzyme, Paradis-Bleau, C., Beaumont, M., Boudreault, L., Lloyd, A., Sanschagrin, F., Bugg, T.D.H., Levesque, R.C., Peptides, 2006, 10.1016/j.peptides.2006.01.017
A specific peptide inhibitor of the class B metallo-β-lactamase L-1 from Stenotrophomonas maltophilia identified using phage display, Sanschagrin, F., Levesque, R.C., Journal of Antimicrobial Chemotherapy, 2005, 10.1093/jac/dkh550
Diabetes: A major co-morbidity of cystic fibrosis, Costa, M., Potvin, S., Berthiaume, Y., Gauthier, L., Jeanneret, A., Lavoie, A., Levesque, R., Chiasson, J.L., Rabasa-Lhoret, R., Diabetes and Metabolism, 2005, 10.1016/S1262-3636(07)70189-1
Peptide inhibitors of the essential cell division protein FtsA, Paradis-Bleau, C., Sanschagrin, F., Levesque, R.C., Protein Engineering, Design and Selection, 2005, 10.1093/protein/gzi008
Heterogeneity among virulence and antimicrobial resistance gene profiles of extraintestinal Escherichia coli isolates of animal and human origin, Maynard, C., Bekal, S., Sanschagrin, F., Levesque, R.C., Brousseau, R., Masson, L., Larivière, S., Harel, J., Journal of Clinical Microbiology, 2004, 10.1128/JCM.42.12.5444-5452.2004
Identification of novel pathogenicity genes by PCR signature-tagged mutagenesis and related technologies., Lehoux, D.E., Sanschagrin, F., Kukavica-Ibrulj, I., Potvin, E., Levesque, R.C., Methods in molecular biology (Clifton, N.J.), 2004, 10.1385/1-59259-763-7:289
Identification of Pseudomonas aeruginosa FtsZ peptide inhibitors as a tool for development of novel antimicrobials [8], Paradis-Bleau, C., Sanschagrin, F., Levesque, R.C., Journal of Antimicrobial Chemotherapy, 2004
Letter to the editor: 1H, 13C and 15N backbone resonance assignments for TEM-1, a 28.9 kDa β-lactamase from E. coli [19], Savard, P.-Y., Sosa-Peinado, A., Levesque, R.C., Makinen, M.W., Gagné, S.M., Journal of Biomolecular NMR, 2004, 10.1023/B:JNMR.0000032503.96942.68
Antimicrobial resistance genes in enterotoxigenic Escherichia coli O149: K91 isolates obtained over a 23-year period from pigs, Maynard, C., Fairbrother, J.M., Bekal, S., Sanschagrin, F., Levesque, R.C., Brousseau, R., Masson, L., Larivière, S., Harel, J., Antimicrobial Agents and Chemotherapy, 2003, 10.1128/AAC.47.10.3214-3221.2003
Combinatorial enzymatic assay for the screening of a new class of bacterial cell wall inhibitors, Zoeiby, A.E., Beaumont, M., Dubuc, E., Sanschagrin, F., Voyer, N., Levesque, R.C., Bioorganic and Medicinal Chemistry, 2003, 10.1016/S0968-0896(02)00447-9
Identification of novel inhibitors of Pseudomonas aeruginosa MurC enzyme derived from phage-displayed peptide libraries, El Zoeiby, A., Sanschagrin, F., Darveau, A., Brisson, J.-R., Levesque, R.C., Journal of Antimicrobial Chemotherapy, 2003, 10.1093/jac/dkg010
In vivo functional genomics of Pseudomonas aeruginosa for high-throughput screening of new virulence factors and antibacterial targets, Potvin, E., Lehoux, D.E., Kukavica-Ibrulj, I., Richard, K.L., Sanschagrin, F., Lau, G.W., Levesque, R.C., Environmental Microbiology, 2003, 10.1046/j.1462-2920.2003.00542.x
Structure and function of the Mur enzymes: Development of novel inhibitors, El Zoeiby, A., Sanschagrin, F., Levesque, R.C., Molecular Microbiology, 2003, 10.1046/j.1365-2958.2003.03289.x
Broad-host-range mobilizable suicide vectors for promoter trapping in gram-negative bacteria, Izallalen, M., Levesque, R.C., Perret, X., Broughton, W.J., Antoun, H., BioTechniques, 2002, 10.2144/02335st04
Differential regulation of twitching motility and elastase production by Vfr in Pseudomonas aeruginosa, Beatson, S.A., Whitchurch, C.B., Sargent, J.L., Levesque, R.C., Mattick, J.S., Journal of Bacteriology, 2002, 10.1128/JB.184.13.3605-3613.2002
Identification of in vivo essential genes from Pseudomonas aeruginosa by PCR-based signature-tagged mutagenesis, Lehoux, D.E., Sanschagrin, F., Levesque, R.C., FEMS Microbiology Letters, 2002, 10.1016/S0378-1097(02)00597-9
PCR screening in signature-tagged mutagenesis of essential genes., Lehoux, D.E., Levesque, R.C., Methods in molecular biology (Clifton, N.J.), 2002, 10.1385/1-59259-177-9:225
Discovering essential and infection-related genes, Lehoux, D.E., Sanschagrin, F., Levesque, R.C., Current Opinion in Microbiology, 2001, 10.1016/S1369-5274(00)00244-7
In vitro reconstruction of the biosynthetic pathway of peptidoglycan cytoplasmic precursor in Pseudomonas aeruginosa, El Zoeiby, A., Sanschagrin, F., Havugimana, P.C., Garnier, A., Levesque, R.C., FEMS Microbiology Letters, 2001, 10.1016/S0378-1097(01)00268-3
Insights into the molecular basis for the carbenicillinase activity of PSE-4 β-lactamase from crystallographic and kinetic studies, Lim, D., Sanschagrin, F., Passmore, L., De Castro, L., Levesque, R.C., Strynadka, N.C.J., Biochemistry, 2001, 10.1021/bi001653v
Cloning, over-expression and purification of Pseudomonas aeruginosa murC encoding uridine diphosphate N-acetylmuramate: L-alanine ligase, El Zoeiby, A., Sanschagrin, F., Lamoureux, J., Darveau, A., Levesque, R.C., FEMS Microbiology Letters, 2000, 10.1016/S0378-1097(00)00003-3
Combinatorial biochemistry and shuffling of TEM, SHV and Streptomyces albus omega loops in PSE-4 class A β-lactamase, Sanschagrin, F., Thériault, E., Sabbagh, Y., Voyer, N., Levesque, R.C., Journal of Antimicrobial Chemotherapy, 2000, 10.1093/jac/45.4.517
Detection of genes essential in specific niches by signature-tagged mutagenesis, Lehoux, D.E., Levesque, R.C., Current Opinion in Biotechnology, 2000, 10.1016/S0958-1669(00)00124-5
Evaluation of inhibition of the carbenicillin-hydrolyzing β-lactamase PSE-4 by the clinically used mechanism-based inhibitors, Therrien, C., Kotra, L.P., Sanschagrin, F., Mobashery, S., Levesque, R.C., FEBS Letters, 2000, 10.1016/S0014-5793(00)01342-9
Genomics of the 35-kb pvd locus and analysis of novel pvdIJK genes implicated in pyoverdine biosynthesis in Pseudomonas aeruginosa, Lehoux, D.E., Sanschagrin, F., Levesque, R.C., FEMS Microbiology Letters, 2000, 10.1016/S0378-1097(00)00314-1
In vivo-induced genes in Pseudomonas aeruginosa, Handfield, M., Lehoux, D.E., Sanschagrin, F., Mahan, M.J., Woods, D.E., Levesque, R.C., Infection and Immunity, 2000, 10.1128/IAI.68.4.2359-2362.2000
Molecular basis of antibiotic resistance and β-lactamase inhibition by mechanism-based inactivators: Perspectives and future directions, Therrien, C., Levesque, R.C., FEMS Microbiology Reviews, 2000, 10.1016/S0168-6445(99)00039-X
Structure-function analysis of α-helix H4 using PSE-4 as a model enzyme representative of class A β-lactamases, Savoie, A., Sanschagrin, F., Palzkill, T., Voyer, N., Levesque, R.C., Protein Engineering, 2000, 10.1093/protein/13.4.267
Defined oligonucleotide tag pools and pcr screening in signature-tagged mutagenesis of essential genes from bacteria, Lehoux, D.E., Sanschagrin, F., Levesque, R.C., BioTechniques, 1999, 10.2144/99263st02
Strategies for isolation of in vivo expressed genes from bacteria, Handfield, M., Levesque, R.C., FEMS Microbiology Reviews, 1999, 10.1016/S0168-6445(98)00033-3
Structure-function studies of Ser-289 in the class C β-lactamase from Enterobacter cloacae P99, Trépanier, S., Knox, J.R., Clairoux, N., Sanschagrin, F., Levesque, R.C., Huletsky, A., Antimicrobial Agents and Chemotherapy, 1999, 10.1128/aac.43.3.543
ASD-GFP vectors for in vivo expression technology in Pseudomonas aeruginosa and other gram-negative bacteria, Handfield, M., Schweizer, H.P., Mahan, M.J., Sanschagrin, F., Hoang, T., Levesque, R.C., BioTechniques, 1998, 10.2144/98242st02
Characterization of a PSE-4 mutant with different properties in relation to penicillanic acid sulfones: Importance of residues 216 to 218 in class A β-lactamases, Sabbagh, Y., Thériault, E., Sanschagrin, F., Voyer, N., Palzkill, T., Levesque, R.C., Antimicrobial Agents and Chemotherapy, 1998, 10.1128/aac.42.9.2319
Molecular heterogeneity of the L-1 metallo-β-lactamase family from Stenotrophomonas maltophilia, Sanschagrin, F., Dufresne, J., Levesque, R.C., Antimicrobial Agents and Chemotherapy, 1998, 10.1128/aac.42.5.1245
Pseudomonas aeruginosa PA01 Bacterial Artificial Chromosomes: Strategies for Mapping, Screening, and Sequencing 100 kb Loci of the 5.9 Mb Genome, Dewar, K., Sabbagh, L., Cardinal, G., Veilleux, F., Sanschagrin, F., Birren, B., Levesque, R.C., Microbial and Comparative Genomics, 1998, 10.1089/omi.1.1998.3.105
Roles of amino acids 161 to 179 in the PSE-4 Ω loop in substrate specificity and in resistance to ceftazidime, Therrien, C., Sanschagrin, F., Palzkill, T., Levesque, R.C., Antimicrobial Agents and Chemotherapy, 1998, 10.1128/aac.42.10.2576
Structure of CARB-4 and AER-1 carbenicillin hydrolyzing β-lactamases, Sanschagrin, F., Bejaoui, N., Levesque, R.C., Antimicrobial Agents and Chemotherapy, 1998, 10.1128/aac.42.8.1966
Physical mapping of 32 genetic markers on the Pseudomonas aeruginosa PAO1 chromosome, Liao, X., Charlebois, I., Ouellet, C., Morency, M.-J., Dewar, K., Lightfoot, J., Foster, J., Siehnel, R., Schweizer, H., Lam, J.S., Hancock, R.E.W., Levesque, R.C., Microbiology, 1996, 10.1099/13500872-142-1-79
Secondary structures and features of the 18S, 5.8S and 26S ribosomal RNAs from the Apicomplexan parasite Toxoplasma gondii, Gagnon, S., Bourbeau, D., Levesque, R.C., Gene, 1996, 10.1016/0378-1119(96)00215-6
Toxoplasma gondii: Structure and characterization of the 26S ribosomal RNA and peptidyl transferase domain, Gagnon, S., Morency, M.-J., Bourbeau, D., Levesque, R.C., Experimental Parasitology, 1996, 10.1006/expr.1996.0082
Comparative analysis of the 16S to 23S ribosomal intergenic spacer sequences of Bacillus thuringiensis strains and subspecies and of closely related species, Bourque, S.N., Valero, J.R., Lavoie, M.C., Levesque, R.C., Applied and Environmental Microbiology, 1995, 10.1128/aem.61.4.1623-1626.1995
Erratum: Comparative analysis of the 16S to 23S ribosomal intergenic spacer sequences of Bacillus thuringiensis strains and subspecies and of closely related species (Applied and Environmental Microbiology 61:4 (1624- 1626)), Bourque, S.N., Valero, J.R., Lavoie, M.C., Levesque, R.C., Applied and Environmental Microbiology, 1995
Primary structure of OXA-3 and phylogeny of oxacillin-hydrolyzing class D β-lactamases, Sanschagrin, F., Couture, F., Levesque, R.C., Antimicrobial Agents and Chemotherapy, 1995, 10.1128/AAC.39.4.887
Detection of the pathogenic parasite Toxoplasma gondii by specific amplification of ribosomal sequences using comultiplex polymerase chain reaction, Guay, J.-M., Dubois, D., Morency, M.-J., Gagnon, S., Mercier, J., Levesque, R.C., Journal of Clinical Microbiology, 1993, 10.1128/jcm.31.2.203-207.1993
Homology between the genes of octopine catabolism of Rhizobium meliloti A3 and corresponding genes from the Ti plasmid, Bergeron, J., Beaulieu, C., Levesque, R.C., Kondorosi, A., Dion, P., Canadian Journal of Microbiology, 1993, 10.1139/m93-158
Identification of endomycorrhizal fungi colonizing roots by fluorescent single-strand conformation polymorphism-polymerase chain reaction, Simon, L., Levesque, R.C., Lalonde, M., Applied and Environmental Microbiology, 1993, 10.1128/aem.59.12.4211-4215.1993
Molecular cloning, complete sequence of the small subunit ribosomal RNA coding region and phylogeny of Toxoplasma gondii, Gagnon, S., Levesque, R.C., Sogin, M.L., Gajadhar, A.A., Molecular and Biochemical Parasitology, 1993, 10.1016/0166-6851(93)90037-X
Multiplex polymerase chain reaction for detection and differentiation of the microbial insecticide Bacillus thuringiensis, Bourque, S.N., Valero, J.R., Mercier, J., Lavoie, M.C., Levesque, R.C., Applied and Environmental Microbiology, 1993, 10.1128/aem.59.2.523-527.1993
Origin and diversification of endomycorrhizal fungi and coincidence with vascular land plants, Simon, L., Bousquet, J., Lévesque, R.C., Lalonde, M., Nature, 1993, 10.1038/363067a0
Role of Ser-238 and Lys-240 in the hydrolysis of third-generation cephalosporins by SHV-type β-lactamases probed by site-directed mutagenesis and three-dimensional modeling, Huletsky, A., Knox, J.R., Levesque, R.C., Journal of Biological Chemistry, 1993
Cloning, sequencing and expression in Escherichia coli of the ptsI gene encoding enzyme I of the phosphoenolpyruvate:sugar phosphotransferase transport system from Streptococcus salivarius, Gagnon, G., Vadeboncoeur, C., Levesque, R.C., Frenette, M., Gene, 1992, 10.1016/0378-1119(92)90163-J
Identification of a ROB-1 β-lactamase in Haemophilus ducreyi, Maclean, I.W., Slaney, L., Juteau, J.-M., Levesque, R.C., Albritton, W.L., Ronald, A.R., Antimicrobial Agents and Chemotherapy, 1992, 10.1128/AAC.36.2.467
Phylogeny of LCR‐1 and OXA‐5 with class A and class D β‐lactamases, Couture, F., Lachapelle, J., Levesque, R.C., Molecular Microbiology, 1992, 10.1111/j.1365-2958.1992.tb00894.x
Physical and genetic mapping of cloned ribosomal DNA from Toxoplasma gondii: primary and secondary structure of the 5S gene, Guay, J.-M., Huot, A., Gagnon, S., Tremblay, A., Levesque, R.C., Gene, 1992, 10.1016/0378-1119(92)90570-F
Rapid quantitation by PCR of endomycorrhizal fungi colonizing roots, Simon, L., Lévesque, R.C., Lalonde, M., Genome Research, 1992, 10.1101/gr.2.1.76
Site-saturation mutagenesis and three-dimensional modelling of rob-1 define a substrate binding role of ser 130 in class a β-lactamases, Juteau, J.-M., Billings, E., Knox, J.R., Levesque, R.C., Protein Engineering, Design and Selection, 1992, 10.1093/protein/5.7.693
A standard numbering scheme for the class A β-lactamases [1], Ambler, R.P., Coulson, A.F.W., Frere, J.-M., Ghuysen, J.-M., Joris, B., Forsman, M., Levesque, R.C., Tiraby, G., Waley, S.G., Biochemical Journal, 1991, 10.1042/bj2760269
Characterization of the blaCARB-3 gene encoding the carbenicillinase-3 β-lactamase of Pseudomonas aeruginosa, Lachapelle, J., Dufresne, J., Levesque, R.C., Gene, 1991, 10.1016/0378-1119(91)90530-O
Construction of a DNA probe and detection of Actinobacillus pleuropneumoniae by using polymerase chain reaction, Sirois, M., Lemire, E.G., Levesque, R.C., Journal of Clinical Microbiology, 1991, 10.1128/jcm.29.6.1183-1187.1991
Molecular characterization of the class II multiresistance transposable element Tn1403 from Pseudomonas aeruginosa, Vezina, G., Levesque, R.C., Antimicrobial Agents and Chemotherapy, 1991, 10.1128/AAC.35.2.313
Molecular distribution of ROB-1 β-lactamase in Actinobacillus pleuropneumoniae, Juteau, J.-M., Sirois, M., Medeiros, A.A., Levesque, R.C., Antimicrobial Agents and Chemotherapy, 1991, 10.1128/AAC.35.7.1397
Systematic site-saturation mutagenesis of ROB-1 β-lactamase: Efficiency of T4 polymerase and oligonucleotide synthesis, Juteau, J.-M., Cote, S., Levesque, R.C., BioTechniques, 1991
Cloning of SHV-2, OHIO-1, and OXA-6 β-lactamases and cloning and sequencing of SHV-1 β-lactamase, Mercier, J., Levesque, R.C., Antimicrobial Agents and Chemotherapy, 1990, 10.1128/AAC.34.8.1577
Nucleotide sequence and phylogeny of SHV-2 β-lactamase, Huletsky, A., Couture, F., Levesque, R.C., Antimicrobial Agents and Chemotherapy, 1990, 10.1128/AAC.34.9.1725
Nucleotide sequence of the PSE-4 carbenicillinase gene and correlations with Staphylococcus aureus PC1 β-lactamase crystal structure, Boissinot, M., Levesque, R.C., Journal of Biological Chemistry, 1990
Sequence analysis and evolutionary perspectives of ROB-1 β-lactamase, Juteau, J.-M., Levesque, R.C., Antimicrobial Agents and Chemotherapy, 1990, 10.1128/AAC.34.7.1354
Structural and functional characterization of tnpI, a recombinase locus in Tn21 and related β-lactamase transposons, Mercier, J., Lachapelle, J., Couture, F., Lafond, M., Vezina, G., Boissinot, M., Levesque, R.C., Journal of Bacteriology, 1990, 10.1128/jb.172.7.3745-3757.1990
Characteristics and comparative study of five Rhizobium meliloti bacteriophages, Werquin, M., Ackermann, H.-W., Levesque, R.C., Current Microbiology, 1989, 10.1007/BF01575946
Decreased outer membrane permeability in imipenem-resistant mutants of Pseudomonas aeruginosa, Trias, J., Dufresne, J., Levesque, R.C., Nikaido, H., Antimicrobial Agents and Chemotherapy, 1989, 10.1128/aac.33.8.1202
Development of gene probes and evolutionary relationships of the PSE-4 bla gene to plasmid-mediated β-lactamases of gram-negative bacteria, Boissinot, M., Huot, A., Mercier, J., Levesque, R.C., Molecular and Cellular Probes, 1989, 10.1016/0890-8508(89)90028-5
Evolutionary perspectives on multiresistance β-lactamase transposons, Lafond, M., Couture, F., Vezina, G., Levesque, R.C., Journal of Bacteriology, 1989, 10.1128/jb.171.12.6423-6429.1989
A colposcopical lesion of the uterine cervix frequently associated with papillomavirus type 16 as detected by in situ and southern blot hybridization: A cytohistological correlation study, Morin, C., Bouchard, C., Fortier, M., Levesque, R., Meisels, A., International Journal of Cancer, 1988, 10.1002/ijc.2910410410
Cloning and expression of the imipenem-hydrolyzing β-lactamase operon from Pseudomonas maltophilia in Escherichia coli, Dufresne, J., Vezina, G., Levesque, R.C., Antimicrobial Agents and Chemotherapy, 1988, 10.1128/AAC.32.6.819
Molecular cloning and expression of the imipenem-hydrolyzing β-lactamase gene from pseudomonas maltophilia in escherichia coli, Dufresne, J., Vezina, G., Levesque, R.C., Clinical Infectious Diseases, 1988, 10.1093/clinids/10.4.806
Molecular structure and interrelationships of multiresistance β-lactamase transposons, Levesque, R.C., Jacoby, G.A., Plasmid, 1988, 10.1016/0147-619X(88)90059-5
Development of natural and synthetic DNA probes for OXA-2 and TEM-1 β-lactamases, Boissinot, M., Mercier, J., Levesque, R.C., Antimicrobial Agents and Chemotherapy, 1987, 10.1128/AAC.31.5.728
Molecular cloning and DNA homology of plasmid-mediated β-lactamase genes, Levesque, R.C., Medeiros, A.A., Jacoby, G.A., MGG Molecular & General Genetics, 1987, 10.1007/BF00333581
Monoclonal antibodies to TEM-1 plasmid-mediated β-lactamase, Morin, C.J., Patel, P.C., Levesque, R.C., Letarte, R., Antimicrobial Agents and Chemotherapy, 1987, 10.1128/AAC.31.11.1761
An animal source for the ROB-1 β-lactamase of Haemophilus influenzae type b, Medeiros, A.A., Levesque, R., Jacoby, G.A., Antimicrobial Agents and Chemotherapy, 1986, 10.1128/AAC.29.2.212
Comparative study of the beta-lactamase activity found in Achromobacter., Levesque, R., Letarte, R., Pechère, J.C., Canadian journal of microbiology, 1983, 10.1139/m83-133
β-lactamases: Clinical and genetic perspectives, Pechère, J.-C., Levesque, R., Journal of Antimicrobial Chemotherapy, 1983, 10.1093/jac/12.6.529
A plasmid-mediated cepbalosporinase from achromobacter species, Levesque, R., Roy, P.H., Letarte, R., Pechere, J.-C., Journal of Infectious Diseases, 1982, 10.1093/infdis/145.2.753
Mapping of a plasmid (pLQ3) from Achromobacter and cloning of its cephalosporinase gene in Escherichia coli, Levesque, R., Roy, P.H., Gene, 1982, 10.1016/0378-1119(82)90057-9
Increase in the in vitro susceptibility of Staphylococcus aureus to antimicrobiol agents in the presence of Candida albicans, DeRepentigny, J., Levesque, R., Mathieu, L.G., Canadian Journal of Microbiology, 1979, 10.1139/m79-066
...
En voir plus
Contribution à l'enseignement aux cycles supérieurs
Étudiant(e)s dirigé(e)s*
Depuis 2009
Alexia Clazina Maria De Jong - Maitrîse avec mémoire - En cours
Sandra Gagnon - Maitrîse avec mémoire - 2012/01
Andrée-Ann Lemieux - Maitrîse avec mémoire - 2012/05
Simone Périnet - Maitrîse avec mémoire - 2014/01
Mathieu Landry - Maitrîse avec mémoire - 2015/09
Encadrement d'étudiant(e)s pour les programmes suivants :
*Les supervisions d’étudiant(e)s de 1er cycle en
stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées
ultérieurement.
Vice-décanat à la recherche et aux études supérieures Pavillon Ferdinand-Vandry Université Laval 1050, avenue de la Médecine, local 4645 Québec (Québec) G1V 0A6 Canada
Catherine Comtois Agente de gestion des études etudes.sup2@fmed.ulaval.ca Biostatistique Épidémiologie Évaluation économique des technologies de la santé Santé publique
Marianne Rivest et Claudia Gonzalez Agentes de gestion des études etudes.sup1@fmed.ulaval.ca Biologie cellulaire et moléculaire Génomique fonctionnelle Médecine moléculaire Microbiologie-immunologie Neurosciences
Isabelle Tremblay Agente de gestion des études etudes.sup3@fmed.ulaval.ca Pédagogie universitaire en sciences de la santé Sciences cliniques et biomédicales Sciences de la réadaptation Prévention et gestion de la santé et de la sécurité au travail