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Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec
Partager la fiche :
Contribution à la recherche
Axe de recherche de l'Université Laval :
L’humain dans son environnement
Thématiques de recherche de la Faculté de
médecine :
Immunologie-infectiologie
Santé cardiovasculaire, respiratoire et métabolisme
Domaines et intérêts de recherche du (de la)
professeur(e) :
Appareil locomoteur et arthrite
Affections cutanées
Santé circulatoire et respiratoire
Maladies inflammatoires du système respiratoire
Asthme
Fibrose kystique
Maladie pulmonaire obstructive chronique
Projets de recherche
Salaire d'un professeur- Fondation de l'Université Laval, Institut universitaire de cardiologie et de pneumologie de Québec, chercheur principal - 2009-07-01 au 2026-06-30
Cellular and molecular mechanisms involved in the biosynthesis and hydrolysis of the endocannabinoid 2-arachidonoyl-glycerol and its congeners- Conseil de recherches en sciences naturelles et génie Canada - Subventions à la découverte SD (individuelles et d'équipe), chercheur principal - 2021-04-01 au 2026-03-31
Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.2- Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 3.2- Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.3- Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.1- Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
Impact of dietary stearidonic acid-rich oil on rheumatoid arthritis- Instituts de recherche en santé du Canada - Subvention Projet, Université de Moncton, co-chercheur - 2019-10-01 au 2024-09-30
Cellular and molecular mechanisms involved in the regulation of the endocannabinoidome in the immune system in health and disease- Instituts de recherche en santé du Canada - Chaires de recherche sans organismes subventionnaires, chercheur principal - 2018-10-01 au 2024-05-31
FMéd --- Canada Excellence Research Chair on the microbiome-endocannabinoidome connection in metabolic health- Instituts de recherche en santé du Canada, Université Laval - Fonds internes - Programme de chaires d'excellence en recherche du Canada, co-chercheur - 2017-06-01 au 2024-05-31
Characterization of the novel metabolite 5-hydroxy-eicosatetraenoyl-glycerol in asthma- Fondation de l'Université Laval, chercheur principal - 2022-01-01 au 2023-12-31
Programme de soutien aux nouveaux chercheurs- Université Laval - Fonds internes - Soutien facultaire aux jeunes chercheurs de la Faculté de médecine, chercheur principal - 2022-01-01 au 2023-12-31
The role of autotaxin and lysophosphatidic acid in the development of calcific aortic valve disease- Instituts de recherche en santé du Canada - Volet Projet: Concours pilotes, co-chercheur - 2016-07-01 au 2021-06-30
COVID-19 trilogy: ARDS, inflammation and coagulopathy- Instituts de recherche en santé du Canada - Subvention de fonctionnement : Possibilité de financement pour une intervention de recherche rapide contre la COVID-19, co-chercheur - 2020-06-01 au 2021-05-31
Understanding the pathogenesis of COVID-19- Instituts de recherche en santé du Canada, Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC) - Subvention de fonctionnement : Possibilité de financement canadienne pour une intervention de recherche rapide contre la maladie à coronavirus 2019 (COVID-19), co-chercheur - 2020-03-01 au 2021-02-28
Évaluation du rôle de l'aspartic peptidase ASPRV1 dans l'asthme- Fondation de l'Université Laval, co-chercheur - 2019-12-01 au 2020-11-30
Defining the endocannabinodiome and the microbiota in asthma and its severity- Secrétariat des programmes interorganismes à l’intention des établissements - Fonds d'excellence en recherche Apogée Canada, chercheur principal - 2018-10-19 au 2020-10-18
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Publications
Investigation of Omega-3 Polyunsaturated Fatty Acid Biological Activity in a Tissue-Engineered Skin Model Involving Psoriatic Cells, Mélissa Simard, Geneviève Rioux, Sophie Morin, Cyril Martin, Sylvain L. Guérin, Nicolas Flamand, Pierre Julien, Julie Fradette, Roxane Pouliot, Journal of Investigative Dermatology, 2021, 10.1016/j.jid.2021.02.755
Oral Capsaicinoid Administration Alters the Plasma Endocannabinoidome and Fecal Microbiota of Reproductive-Aged Women Living with Overweight and Obesity, Claudia Manca, Sébastien Lacroix, Francine Pérusse, Nicolas Flamand, Yvon Chagnon, Vicky Drapeau, Angelo Tremblay, Vincenzo Di Marzo, Cristoforo Silvestri, Biomedicines, 2021, 10.3390/biomedicines9091246
Biosynthesis of the Novel Endogenous 15-Lipoxygenase Metabolites N-13-Hydroxy-octodecadienoyl-ethanolamine and 13-Hydroxy-octodecadienoyl-glycerol by Human Neutrophils and Eosinophils, Anne-Sophie Archambault, Francesco Tinto, Élizabeth Dumais, Volatiana Rakotoarivelo, Magdalena Kostrzewa, Pier-Luc Plante, Cyril Martin, Mélissa Simard, Cristoforo Silvestri, Roxane Pouliot, Michel Laviolette, Louis-Philippe Boulet, ROSA MARIA VITALE, ALESSIA LIGRESTI, Vincenzo Di Marzo, Nicolas Flamand, Cells, 2021, 10.3390/cells10092322
Chemokines and eicosanoids fuel the hyperinflammation within the lungs of patients with severe COVID-19., , The Journal of allergy and clinical immunology, 2021, 10.1016/j.jaci.2021.05.032
High levels of eicosanoids and docosanoids in the lungs of intubated COVID-19 patients., , FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, 10.1096/fj.202100540r
Role of the Endocannabinoid System in the Adipose Tissue with Focus on Energy Metabolism, Volatiana Rakotoarivelo, Jyoti Sihag, Nicolas Flamand, Cells, 2021, 10.3390/cells10061279
Beneficial Effects of Akkermansia muciniphila Are Not Associated with Major Changes in the Circulating Endocannabinoidome but Linked to Higher Mono-Palmitoyl-Glycerol Levels as New PPARα Agonists, Clara Depommier, Rosa Maria Vitale, Fabio Arturo Iannotti, Cristoforo Silvestri, Nicolas Flamand, Céline Druart, Amandine Everard, Rudy Pelicaen, Dominique Maiter, Jean-Paul Thissen, Audrey Loumaye, Michel P. Hermans, Nathalie M. Delzenne, Willem M. de Vos, Vincenzo Di Marzo, Patrice D. Cani, Cells, 2021, 10.3390/cells10010185
Linking the Endocannabinoidome with Specific Metabolic Parameters in an Overweight and Insulin-Resistant Population: From Multivariate Exploratory Analysis to Univariate Analysis and Construction of Predictive Models, Clara Depommier, Nicolas Flamand, Rudy Pelicaen, Dominique Maiter, Jean-Paul Thissen, Audrey Loumaye, Michel P. Hermans, Amandine Everard, Nathalie M. Delzenne, Vincenzo Di Marzo, Patrice D. Cani, Cells, 2021, 10.3390/cells10010071
Lipid storm within the lungs of severe COVID-19 patients: Extensive levels of cyclooxygenase and lipoxygenase-derived inflammatory metabolites, Archambault A, Zaid Y, Rakotoarivelo V, Doré É, Dubuc I, Martin C, Amar Y, Cheikh A, Fares H, El Hassani A, Tijani Y, Laviolette M, Boilard É, dummy-AUTHOR_name, Flamand N, 2020, 10.1101/2020.12.04.20242115
[Extracellular molecules controlling the contraction of airway smooth muscle and their potential contribution to bronchial hyperresponsiveness]., , Revue des maladies respiratoires, 2020, 10.1016/j.rmr.2020.03.009
Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism, Charlotte Lefort, Martin Roumain, Matthias Van Hul, Marialetizia Rastelli, Rita Manco, Isabelle Leclercq, Nathalie M. Delzenne, Vincenzo Di Marzo, Nicolas Flamand, serge luquet, Cristoforo Silvestri, Giulio G. Muccioli, Cani PD, Cells, 2020, 10.3390/cells9051247
RGS4 promotes allergen- and aspirin-associated airway hyperresponsiveness by inhibiting PGE2 biosynthesis., , The Journal of allergy and clinical immunology, 2020, 10.1016/j.jaci.2020.03.004
LPS induces ALOX5 promoter activation and 5-lipoxygenase expression in human monocytic cells., , Prostaglandins, leukotrienes, and essential fatty acids, 2020, 10.1016/j.plefa.2020.102078
Endocannabinoid hydrolysis inhibition unmasks that unsaturated fatty acids induce a robust biosynthesis of 2-arachidonoyl-glycerol and its congeners in human myeloid leukocytes., , FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, 10.1096/fj.201902916r
Rapid and Concomitant Gut Microbiota and Endocannabinoidome Response to Diet-Induced Obesity in Mice., , mSystems, 2019, 10.1128/msystems.00407-19
Germ-free mice exhibit profound gut microbiota-dependent alterations of intestinal endocannabinoidome signaling., , Journal of lipid research, 2019, 10.1194/jlr.ra119000424
Human leukocytes differentially express endocannabinoid-glycerol lipases and hydrolyze 2-arachidonoyl-glycerol and its metabolites from the 15-lipoxygenase and cyclooxygenase pathways., , Journal of leukocyte biology, 2019, 10.1002/jlb.3a0919-049rrr
Lipopolysaccharide impacts murine CD103+ DC differentiation, altering the lung DC population balance., , European journal of immunology, 2019, 10.1002/eji.201847910
Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis., , Nature communications, 2019, 10.1038/s41467-018-08051-7
20-Hydroxy- and 20-carboxy-leukotriene (LT) B4 downregulate LTB4 -mediated responses of human neutrophils and eosinophils., , Journal of leukocyte biology, 2019, 10.1002/jlb.ma0718-306r
Methylation profiles of IL33 and CCL26 in bronchial epithelial cells are associated with asthma., , Epigenomics, 2018, 10.2217/epi-2018-0044
Comparison of eight 15-lipoxygenase (LO) inhibitors on the biosynthesis of 15-LO metabolites by human neutrophils and eosinophils., , PloS one, 2018, 10.1371/journal.pone.0202424
Dormant 5-lipoxygenase in inflammatory macrophages is triggered by exogenous arachidonic acid, Carlos A. Sorgi, Simona Zarini, Sarah A. Martin, Raphael L. Sanchez, Rodrigo F. Scandiuzzi, Miguel A. Gijón, Carlos Guijas, Nicolas Flamand, Robert C. Murphy, Lucia H. Faccioli, Scientific Reports, 2017, 10.1038/s41598-017-11496-3
Regulation of Eosinophil and Group 2 Innate Lymphoid Cell Trafficking in Asthma., , Frontiers in medicine, 2017, 10.3389/fmed.2017.00136
Hypersensitivity pneumonitis onset and severity is regulated by CD103 dendritic cell expression., , PloS one, 2017, 10.1371/journal.pone.0179678
An in vitro study examining the duration between deep inspirations on the rate of renarrowing., , Respiratory physiology & neurobiology, 2017, 10.1016/j.resp.2017.04.013
The Endocannabinoid Metabolite Prostaglandin E2 (PGE2)-Glycerol Inhibits Human Neutrophil Functions: Involvement of Its Hydrolysis into PGE2 and EP Receptors., , Journal of immunology (Baltimore, Md. : 1950), 2017, 10.4049/jimmunol.1601767
Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12., , Biochimica et biophysica acta. Molecular and cell biology of lipids, 2017, 10.1016/j.bbalip.2017.02.015
A Phosphorylatable Sphingosine Analog Induces Airway Smooth Muscle Cytostasis and Reverses Airway Hyperresponsiveness in Experimental Asthma., , Frontiers in pharmacology, 2017, 10.3389/fphar.2017.00078
Leukotriene B₄ Metabolism and p70S6 Kinase 1 Inhibitors: PF-4708671 but Not LY2584702 Inhibits CYP4F3A and the ω-Oxidation of Leukotriene B₄ In Vitro and In Cellulo., , PloS one, 2017, 10.1371/journal.pone.0169804
Impact of Cannabis, Cannabinoids, and Endocannabinoids in the Lungs., , Frontiers in pharmacology, 2016, 10.3389/fphar.2016.00317
The CB2 receptor and its role as a regulator of inflammation., , Cellular and molecular life sciences : CMLS, 2016, 10.1007/s00018-016-2300-4
Plasma eicosanoid profiles determined by high-performance liquid chromatography coupled with tandem mass spectrometry in stimulated peripheral blood from healthy individuals and sickle cell anemia patients in treatment., , Analytical and bioanalytical chemistry, 2016, 10.1007/s00216-016-9445-8
Cellular analysis of the histamine H4 receptor in human myeloid cells., , Biochemical pharmacology, 2016, 10.1016/j.bcp.2016.01.007
Activation of TAK1 by chemotactic and growth factors, and its impact on human neutrophil signaling and functional responses, Sylvain-Prévost, S., Ear, T., Simard, F.A., Fortin, C.F., Dubois, C.M., Flamand, N., McDonald, P.P., Journal of Immunology, 2015, 10.4049/jimmunol.1402752
Correlation between CCL26 production by human bronchial epithelial cells and airway eosinophils: Involvement in patients with severe eosinophilic asthma, Larose, M.-C., Chakir, J., Archambault, A.-S., Joubert, P., Provost, V., Laviolette, M., Flamand, N., Journal of Allergy and Clinical Immunology, 2015, 10.1016/j.jaci.2015.02.039
Pulmonary CD103 expression regulates airway inflammation in asthma, Bernatchez, E., Gold, M.J., Langlois, A., Lemay, A.-M., Brassard, J., Flamand, N., Marsolais, D., McNagny, K.M., Blanchet, M.-R., American Journal of Physiology - Lung Cellular and Molecular Physiology, 2015, 10.1152/ajplung.00319.2014
Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoylglycerol and arachidonoyl-ethanolamide, and their metabolites, Turcotte, C., Chouinard, F., Lefebvre, J.S., Flamand, N., Journal of Leukocyte Biology, 2015, 10.1189/jlb.3RU0115-021R
The intracellular localisation and phosphorylation profile of the human 5-lipoxygenase A13 isoform differs from that of its full length counterpart, Allain, E.P., Boudreau, L.H., Flamand, N., Surette, M.E., Samant, R., PLoS ONE, 2015, 10.1371/journal.pone.0132607
Treatment with a sphingosine analog after the inception of house dust mite-induced airway inflammation alleviates key features of experimental asthma, Gendron, D., Lemay, A.-M., Tremblay, C., Lai, L.J.A., Langlois, A., Bernatchez, T., Flamand, N., Blanchet, M.-R., Don, A.S., Bossé, Y., Bissonnette, T., Marsolais, D., Respiratory Research, 2015, 10.1186/s12931-015-0180-z
Mechanisms of human eosinophil migration induced by the combination of IL-5 and the endocannabinoid 2-arachidonoyl-glycerol, Larose, M.-C., Turcotte, C., Chouinard, F., Ferland, C., Martin, C., Provost, V., Laviolette, M., Flamand, N., Journal of Allergy and Clinical Immunology, 2014, 10.1016/j.jaci.2013.12.1081
2-arachidonoyl-glycerol- and arachidonic acid-stimulated neutrophils releaseantimicrobial effectors against E. coli, S. aureus, HSV-1, and RSV, Chouinard, F., Turcotte, C., Guan, X., Larose, M.-C., Poirier, S., Bouchard, L., Provost, V., Flamand, L., Grandvaux, N., Flamand, N., Journal of Leukocyte Biology, 2013, 10.1189/jlb.0412200
CCL26/eotaxin-3 is more effective to induce the migration of eosinophils of asthmatics than CCL11/eotaxin-1 and CCL24/eotaxin-2, Provost, V., Larose, M.-C., Langlois, A., Rola-Pleszczynski, M., Flamand, N., Laviolette, M., Journal of Leukocyte Biology, 2013, 10.1189/jlb.0212074
Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human polymorphonuclear leukocytes, Boudreau, L.H., Maillet, J., LeBlanc, L.M., Jean-François, J., Touaibia, M., Flamand, N., Surette, M.E., PLoS ONE, 2012, 10.1371/journal.pone.0031833
Leukotriene D4 and Interleukin-13 Cooperate to Increase the Release of Eotaxin-3 by Airway Epithelial Cells, Provost, V., Langlois, A., Chouinard, F., Rola-Pleszczynski, M., Chakir, J., Flamand, N., Laviolette, M., PLoS ONE, 2012, 10.1371/journal.pone.0043544
Novel 5-lipoxygenase isoforms affect the biosynthesis of 5-lipoxygenase products, Boudreau, L.H., Bertin, J., Robichaud, P.P., Laflamme, M., Ouellette, R.J., Flamand, N., Surette, M.E., FASEB Journal, 2011, 10.1096/fj.10-173856
The endocannabinoid 2-arachidonoyl-glycerol activates human neutrophils: Critical role of its hydrolysis and de novo leukotriene B4 biosynthesis, Chouinard, F., Lefebvre, J.S., Navarro, P., Bouchard, L., Ferland, C., Lalancette-Hébert, M., Marsolais, D., Laviolette, M., Flamand, N., Journal of Immunology, 2011, 10.4049/jimmunol.1002853
Crucial implication of protein kinase C (PKC)-δ, PKC-ζ, ERK-1/2, and p38 MAPK in migration of human asthmatic eosinophils, Langlois, A., Chouinard, F., Flamand, N., Ferland, C., Rola-Pleszczynski, M., Laviolette, M., Journal of Leukocyte Biology, 2009, 10.1189/jlb.0808492
Phosphorylation of serine 271 on 5-Lipoxygenase and its role in nuclear export, Flamand, N., Luo, M., Peters-Golden, M., Brock, G.T., Journal of Biological Chemistry, 2009, 10.1074/jbc.M805593200
Reprogramming of a subpopulation of human blood neutrophils by prolonged exposure to cytokines, Chakravarti, A., Rusu, D., Flamand, N., Borgeat, P., Poubelle, P.E., Laboratory Investigation, 2009, 10.1038/labinvest.2009.74
Characterization of prostaglandin E2 generation through the cyclooxygenase (COX)-2 pathway in human neutrophils, St-Onge, M., Flamand, N., Biarc, J., Picard, S., Bouchard, L., Dussault, A.-A., Laflamme, C., James, M.J., Caughey, G.E., Cleland, L.G., Borgeat, P., Pouliot, M., Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 2007, 10.1016/j.bbalip.2007.06.002
Leukotrienes: Mediators that have been typecast as villains, Flamand, N., Mancuso, P., Serezani, C.H.C., Brock, T.G., Cellular and Molecular Life Sciences, 2007, 10.1007/s00018-007-7228-2
NADPH oxidase deficiency results in reduced alveolar macrophage 5-lipoxygenase expression and decreased leukotriene synthesis, Coffey, M.J., Serezani, C.H., Phare, S.M., Flamand, N., Peters-Golden, M., Journal of Leukocyte Biology, 2007, 10.1189/jlb.0107019
Specific leukotriene receptors couple to distinct G proteins to effect stimulation of alveolar macrophage host defense functions, Peres, C.M., Aronoff, D.M., Serezani, C.H., Flamand, N., Faccioli, L.H., Peters-Golden, M., Journal of Immunology, 2007
Arachidonic acid regulates the translocation of 5-lipoxygenase to the nuclear membranes in human neutrophils, Flamand, N., Lefebvre, J., Surette, M.E., Picard, S., Borgeat, P., Journal of Biological Chemistry, 2006, 10.1074/jbc.M506513200
Differential regulation by leukotrienes and calcium of Fcγ receptor-induced phagocytosis and Syk activation in dendritic cells versus macrophages, Canetti, C., Aronoff, D.M., Choe, M., Flamand, N., Wettlaufer, S., Toews, G.B., Chen, G.-H., Peters-Golden, M., Journal of Leukocyte Biology, 2006, 10.1189/jlb.0705374
Effects of pyrrophenone, an inhibitor of group IVA phospholipase A 2, on eicosanoid and PAF biosynthesis in human neutrophils, Flamand, N., Picard, S., Lemieux, L., Pouliot, M., Bourgoin, S.G., Borgeat, P., British Journal of Pharmacology, 2006, 10.1038/sj.bjp.0706879
Inhibition of platelet-activating factor biosynthesis by adenosine and histamine in human neutrophils: Involvement of cPLA2α and reversal by lyso-PAF, Flamand, N., Lefebvre, J., Lapointe, G., Picard, S., Lemieux, L., Bourgoin, S.G., Borgeat, P., Journal of Leukocyte Biology, 2006, 10.1189/jlb.1005614
Metabolism of arachidonic acid to eicosanoids within the nucleus, Luo, M., Flamand, N., Brock, T.G., Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 2006, 10.1016/j.bbalip.2006.02.018
Phosphorylation by protein kinase A inhibits nuclear import of 5-lipoxygenase, Luo, M., Jones, S.M., Flamand, N., Aronoff, D.M., Peters-Golden, M., Brock, T.G., Journal of Biological Chemistry, 2005, 10.1074/jbc.M507045200
Histamine-induced inhibition of leukotriene biosynthesis in human neutrophils: Involvement of the H 2 receptor and cAMP, Flamand, N., Plante, H., Picard, S., Laviolette, M., Borgeat, P., British Journal of Pharmacology, 2004, 10.1038/sj.bjp.0705654
IL-16 activates plasminogen-plasmin system and promotes human eosinophil migration into extracellular matrix via CCR3-chemokine-mediated signaling and by modulating CD4 eosinophil expression, Ferland, C., Flamand, N., Davoine, F., Chakir, J., Laviolette, M., Journal of Immunology, 2004
Arachidonic acid activates phospholipase D in human neutrophils; essential role of endogenous leukotriene B4 and inhibition by adenosine A 2A receptor engagement, Grenier, S., Flamand, N., Pelletier, J., Naccache, P.H., Borgeat, P., Bourgoin, S.G., Journal of Leukocyte Biology, 2003, 10.1189/jlb.0702371
Expression of membrane type-4 matrix metalloproteinase (metalloproteinase- 17) by human eosinophils, Gauthier, M.-C., Racine, C., Ferland, C., Flamand, N., Chakir, J., Tremblay, G.M., Laviolette, M., International Journal of Biochemistry and Cell Biology, 2003, 10.1016/S1357-2725(03)00136-5
Androgen inactivation in human lung fibroblasts: Variations in levels of 17β-hydroxysteroid dehydrogenase type 2 and 5α-reductase activity compatible with androgen inactivation, Provost, P.R., Blomquist, C.H., Drolet, R., Flamand, N., Tremblay, Y., Journal of Clinical Endocrinology and Metabolism, 2002, 10.1210/jc.87.8.3883
Cyclic AMP-mediated inhibition of 5-lipoxygenase translocation and leukotriene biosynthesis in human neutrophils, Flamand, N., Surette, M.E., Picard, S., Bourgoin, S., Borgeat, P., Molecular Pharmacology, 2002, 10.1124/mol.62.2.250
Eotaxin promotes eosinophil transmigration via the activation of the plasminogen-plasmin system, Ferland, C., Guilbert, M., Davoine, F., Flamand, N., Chakir, J., Laviolette, M., Journal of Leukocyte Biology, 2001
Suppressive effects of adenosine on the 5-lipoxygenase pathway in human polymorphonuclear leukocytes, Flamand, N., Plante, H., Picard, S., Austin, M., Surette, M.E., Krump, E., Bourgoin, S., Borgeat, P., Drug Development Research, 2001, 10.1002/ddr.1140
Adenosine, a potent natural suppressor of arachidonic acid release and leukotriene biosynthesis in human neutrophils, Flamand, N., Boudreault, S., Picard, S., Austin, M., Surette, M.E., Plante, H., Krump, E., Vallée, M.-J., Gilbert, C., Naccache, P., Laviolette, M., Borgeat, P., American Journal of Respiratory and Critical Care Medicine, 2000
Androgen formation and metabolism in the pulmonary epithelial cell line A549: Expression of 17β-hydroxysteroid dehydrogenase type 5 and 3α-hydroxysteroid dehydrogenase type 3, Provost, P.R., Blomquist, C.H., Godin, C., Huang, X.-F., Flamand, N., Luu-The, V., Nadeau, D., Tremblay, Y., Endocrinology, 2000, 10.1210/en.141.8.2786
5-Oxo-6,8,11,14-eicosatetraenoic acid induces important eosinophil transmigration through basement membrane components: Comparison of normal and asthmatic eosinophils, Guilbert, M., Ferland, C., Bossé, M., Flamand, N., Lavigne, S., Laviolette, M., American Journal of Respiratory Cell and Molecular Biology, 1999
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Contribution à l'enseignement aux cycles supérieurs
Étudiant(e)s dirigé(e)s*
Depuis 2009
Jean-Philippe C Lavoie - Maitrîse avec mémoire - En cours
Francesco Tinto - Post-doctorat - En cours
Oumaima Azeggouar wallen - Doctorat - En cours
Volatiana Rakotoarivelo - Post-doctorat - En cours
Elizabeth Dumais - Maitrîse avec mémoire - En cours
Mélissa Simard - Post-doctorat - En cours
Katherine Boulay - Maitrîse avec mémoire - 2011/01
Luc Boudreau - Doctorat - 2012/01
François Chouinard - Doctorat - 2012/01
Stéphanie Jean - Maitrîse avec mémoire - 2012/01
Marie-Chantal Larose - Maitrîse avec mémoire - 2015/01
Caroline Turcotte - Maitrîse avec mémoire - 2015/05
Anne-Sophie Archambault - Maitrîse avec mémoire - 2018/01
Samuel Poirier - Doctorat - 2019/05
Encadrement d'étudiant(e)s pour les programmes suivants :
*Les supervisions d’étudiant(e)s de 1er cycle en
stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées
ultérieurement.
Vice-décanat à la recherche et aux études supérieures Pavillon Ferdinand-Vandry Université Laval 1050, avenue de la Médecine, local 4645 Québec (Québec) G1V 0A6 Canada
Catherine Comtois Agente de gestion des études etudes.sup2@fmed.ulaval.ca Biostatistique Épidémiologie Évaluation économique des technologies de la santé Santé publique
Marianne Rivest et Claudia Gonzalez Agentes de gestion des études etudes.sup1@fmed.ulaval.ca Biologie cellulaire et moléculaire Génomique fonctionnelle Médecine moléculaire Microbiologie-immunologie Neurosciences
Isabelle Tremblay Agente de gestion des études etudes.sup3@fmed.ulaval.ca Pédagogie universitaire en sciences de la santé Sciences cliniques et biomédicales Sciences de la réadaptation Prévention et gestion de la santé et de la sécurité au travail