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Marie-Annick Clavel

Professeure titulaire

Marie-Annick Clavel
Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec
Centre de recherche de l'IUCPQ
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Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Santé cardiovasculaire, respiratoire et métabolisme
Santé des populations et pratiques optimales en santé

Domaines et intérêts de recherche du (de la) professeur(e) :

Santé circulatoire et respiratoire
  • Maladies cardiovasculaires
  • Fibrose cardiaque
Santé différentielle des sexes
  • Épidémiologie différentielle des sexes

Projets de recherche

  • Imaging Substudy of the BEST Trial: Balloon-Expandable versus Self-expanding Transcatheter Heart Valve for Treatment of Symptomatic Native Aortic Valve Stenosis - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2022-10-01 au 2027-09-30
  • Blocking the Effects of Serotonin to Prevent Ischemic Mitral Regurgitation: a Randomized Trial - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2022-04-01 au 2027-03-31
  • Impact of an Angiotensin Receptor Blocker in Aortic Stenosis - a Randomized Controlled Trial - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2021-04-01 au 2026-03-31
  • Impact de la testostérone sur la production de calcium par des cellules de valve aortique en culture - Fondation de l'Institut universitaire de cardiologie et de pneumologie de Québec, chercheur principal - 2024-01-01 au 2025-12-31
  • Canada Research Chair in Women Valvular Heart Health - Instituts de recherche en santé du Canada - Chaires de recherche du Canada - Fonctionnement, chercheur principal - 2020-07-01 au 2025-06-30
  • Effet du Candesartan sur la progression de la sténose aortique - Registre - Fondation de l'Institut universitaire de cardiologie et de pneumologie de Québec, chercheur principal - 2023-01-01 au 2024-12-31
  • Économie salariale générée par mandat CPAUL utilisée en fonds de recherche - Université Laval - Fonds internes, chercheur principal - 2022-09-01 au 2024-08-31
  • Elucidating the role of lipoprotein(a) in calcific aortic valve stenosis using novel proteomic and imaging approaches - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2019-10-01 au 2023-09-30
  • Sex-dependent differences in pathophysiological mechanisms, presentation, outcome, and treatment of aortic valve stenosis - Fondation des maladies du coeur et de l'AVC du Canada - Bourse nationale de nouveau chercheur, chercheur principal - 2019-07-01 au 2023-06-30
  • 2022 Canadian Cardiovascular Society - Heart & Stroke / Richard Lewar Centre of Excellence - BI/Lilly Cardiometabolic Research Award - Projet : Sex-Specific Cardiometabolic Determinants of Left Ventricular Remodeling in Aortic Stenosis - Société canadienne de cardiologie, chercheur principal - 2022-04-01 au 2023-03-31
  • Impact des hormones sexuelles sur le remodelage de la valve aortique chez les femmes - Fondation de l'Institut universitaire de cardiologie et de pneumologie de Québec, chercheur principal - 2022-01-01 au 2022-12-31
  • Sex-dependent pathophysiological mechanisms in aortic valve stenosis - Fondation des maladies du coeur et de l'AVC du Canada - Subventions de recherche, chercheur principal - 2018-07-01 au 2022-06-30
  • Multi-omic approach to sex-differences in aortic stenosis - Fondation des maladies du coeur et de l'AVC du Canada, chercheur principal - 2021-07-01 au 2022-06-30
  • Programme de soutien aux nouveaux détenteurs de Chaire de recherche du Canada - Université Laval - Fonds internes - Fonds de soutien aux professeurs-chercheurs bénéficiant d’une Chaire de recherche du Canada, chercheur principal - 2020-07-01 au 2022-06-30
  • Un nano-vaccin contre les maladies cardiovasculaires - Fonds de recherche du Québec - Société et culture - Audace, co-chercheur - 2020-04-01 au 2022-03-31
  • FEI du projet FCI « Sex-specific differences in Aortic stenosis » - Fondation Canadienne pour l'innovation (La) - Fonds d'exploitation des infrastructures (FEI), chercheur principal - 2021-04-01 au 2022-03-31
  • Stage d'été « Carrière été » - Emploi et Développement Social Canada (EDSC) - Emplois d'été Canada, chercheur principal - 2017-05-15 au 2020-08-15

Publications

  • Incidence, risk factors, clinical impact, and management of bioprosthesis structural valve degeneration., , Current opinion in cardiology, 2017, 10.1097/hco.0000000000000372
  • A nationwide contemporary epidemiological portrait of valvular heart diseases., , Heart (British Cardiac Society), 2017, 10.1136/heartjnl-2017-311472
  • Relationship Between QT Interval and Outcome in Low-Flow Low-Gradient Aortic Stenosis With Low Left Ventricular Ejection Fraction., , Journal of the American Heart Association, 2016, 10.1161/JAHA.116.003980
  • Twenty-Year Outcome After Mitral Repair Versus Replacement for Severe Degenerative Mitral Regurgitation: Analysis of a Large, Prospective, Multicenter, International Registry., , Circulation, 2016, 10.1161/circulationaha.116.023340
  • Hemodynamic Deterioration of Surgically Implanted Bioprosthetic Aortic Valves., , Journal of the American College of Cardiology, 2018, 10.1016/j.jacc.2018.04.064
  • Clinical Value of Stress Transaortic Flow Rate During Dobutamine Echocardiography in Reduced Left Ventricular Ejection Fraction, Low-Gradient Aortic Stenosis: A Multicenter Study, , Circulation: Cardiovascular Imaging, 2021, 10.1161/circimaging.121.012809
  • Impact of AVR on LV Remodeling and Function in Paradoxical Low-Flow, Low-Gradient Aortic Stenosis With Preserved LVEF., , JACC. Cardiovascular imaging, 2016, 10.1016/j.jcmg.2016.07.009
  • ApoB/ApoA-I Ratio is Associated With Faster Hemodynamic Progression of Aortic Stenosis: Results From the PROGRESSA (Metabolic Determinants of the Progression of Aortic Stenosis) Study., , Journal of the American Heart Association, 2018, 10.1161/JAHA.117.007980
  • The marvel of percutaneous cardiovascular devices in the elderly., , Annals of the New York Academy of Sciences, 2010, 10.1111/j.1749-6632.2010.05517.x
  • Characteristics and usefulness of unintended premature ventricular contraction during invasive assessment of aortic stenosis., , International journal of cardiology, 2020, 10.1016/j.ijcard.2020.02.053
  • How Do We Reconcile Echocardiography, Computed Tomography, and Hybrid Imaging in Assessing Discordant Grading of Aortic Stenosis Severity?, , JACC. Cardiovascular imaging, 2019, 10.1016/j.jcmg.2018.11.027
  • Impact of classic and paradoxical low flow on survival after aortic valve replacement for severe aortic stenosis., , Journal of the American College of Cardiology, 2015, 10.1016/j.jacc.2014.11.047
  • Transvalvular Flow, Sex, and Survival After Valve Replacement Surgery in Patients With Severe Aortic Stenosis., , Journal of the American College of Cardiology, 2020, 10.1016/j.jacc.2020.02.065
  • Mitral Annular Dynamics in Mitral Annular Calcification: A Three-Dimensional Imaging Study., , Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2015, 10.1016/j.echo.2015.03.002
  • Low-gradient aortic stenosis., , European heart journal, 2016, 10.1093/eurheartj/ehw096
  • Aortic stenosis: what is the role of aging processes?, , Aging, 2019, 10.18632/aging.101826
  • Long-Term Implications of Atrial Fibrillation in Patients With Degenerative Mitral Regurgitation., , Journal of the American College of Cardiology, 2019, 10.1016/j.jacc.2018.10.067
  • Patient Care Journey for Patients with Heart Valve Disease., , The Canadian journal of cardiology, 2022, 10.1016/j.cjca.2022.02.025
  • Comparison of Early Surgical or Transcatheter Aortic Valve Replacement Versus Conservative Management in Low-Flow, Low-Gradient Aortic Stenosis Using Inverse Probability of Treatment Weighting: Results From the TOPAS Prospective Observational Cohort Study., , Journal of the American Heart Association, 2020, 10.1161/jaha.120.017870
  • Transcatheter Aortic Valve Replacement in Patients With Low-Flow, Low-Gradient Aortic Stenosis: The TOPAS-TAVI Registry., , Journal of the American College of Cardiology, 2018, 10.1016/j.jacc.2018.01.054
  • Genetic Association Analyses Highlight IL6, ALPL, and NAV1 As 3 New Susceptibility Genes Underlying Calcific Aortic Valve Stenosis., , Circulation. Genomic and precision medicine, 2019, 10.1161/circgen.119.002617
  • Cardiac magnetic resonance versus transthoracic echocardiography for the assessment and quantification of aortic regurgitation in patients undergoing transcatheter aortic valve implantation., , Heart (British Cardiac Society), 2014, 10.1136/heartjnl-2014-305615
  • Prevalence of left ventricle non-compaction criteria in adult patients with bicuspid aortic valve versus healthy control subjects., , Open heart, 2018, 10.1136/openhrt-2018-000869
  • Low and elevated B-type natriuretic peptide levels are associated with increased mortality in patients with preserved ejection fraction undergoing transcatheter aortic valve replacement: an analysis of the PARTNER II trial and registry., , European heart journal, 2020, 10.1093/eurheartj/ehz892
  • Pathophysiology and management of multivalvular disease., , Nature reviews. Cardiology, 2016, 10.1038/nrcardio.2016.57
  • Reply, , JACC: Cardiovascular Interventions, 2021, 10.1016/j.jcin.2021.03.029
  • Impact of Paravalvular Leak on Outcomes After Transcatheter Aortic Valve Implantation: Meta-Analysis of Kaplan-Meier-derived Individual Patient Data., Ramlawi B, Pibarot P, Clavel MA, Ruhparwar A, Weymann A, Kaple R, Pasala T, Macedo FY, Sicouri S, Erten O, Tasoudis P, Van den Eynde J, Jacquemyn X, Sá MP, Structural heart : the journal of the Heart Team, 2022, 10.1016/j.shj.2022.100118
  • Therapeutic Management of Low-Gradient Aortic Stenosis: First Assess the State of the Schrödinger Cat Before Making a Decision., , Circulation. Cardiovascular interventions, 2017, 10.1161/circinterventions.117.005320
  • Low-Flow Aortic Stenosis, , JACC: Cardiovascular Imaging, 2021, 10.1016/j.jcmg.2021.01.026
  • Comparison of the hemodynamic performance of percutaneous and surgical bioprostheses for the treatment of severe aortic stenosis., , Journal of the American College of Cardiology, 2009, 10.1016/j.jacc.2009.01.060
  • Impact of hypertension and renin-angiotensin system inhibitors in aortic stenosis., , European journal of clinical investigation, 2013, 10.1111/eci.12169
  • Contrast-enhanced computed tomography assessment of aortic stenosis, , Heart, 2021, 10.1136/heartjnl-2020-318556
  • Subclinical bioprosthetic aortic valve thrombosis: clinical and translational implications., , Current opinion in cardiology, 2017, 10.1097/hco.0000000000000373
  • Mitral Regurgitation in Low-Flow, Low-Gradient Aortic Stenosis Patients Undergoing TAVR: Insights From the TOPAS-TAVI Registry., , JACC. Cardiovascular interventions, 2020, 10.1016/j.jcin.2019.11.042
  • The right parasternal window: when Doppler-beam alignment may be life-saving in patients with aortic valve stenosis., , Journal of cardiovascular medicine (Hagerstown, Md.), 2020, 10.2459/jcm.0000000000000971
  • Significance of Left Ventricular Ejection Time in Primary Mitral Regurgitation., , The American journal of cardiology, 2022, 10.1016/j.amjcard.2022.05.019
  • Echocardiographic predictors of outcomes in adults with aortic stenosis., , Heart (British Cardiac Society), 2016, 10.1136/heartjnl-2015-308742
  • Paradoxical low flow aortic valve stenosis: incidence, evaluation, and clinical significance., , Current cardiology reports, 2014, 10.1007/s11886-013-0431-x
  • Effect of size and position of self-expanding transcatheter valve on haemodynamics following valve-in-valve procedure in small surgical bioprostheses: an in vitro study., , EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2018, 10.4244/eij-d-17-00875
  • Insulin resistance and LVH progression in patients with calcific aortic stenosis: a substudy of the ASTRONOMER trial., , JACC. Cardiovascular imaging, 2013, 10.1016/j.jcmg.2012.11.004
  • A Decade of Revolutions in Calcific Aortic Stenosis., , Cardiology clinics, 2020, 10.1016/j.ccl.2019.10.001
  • Structural Deterioration of Transcatheter Versus Surgical Aortic Valve Bioprostheses in the PARTNER-2 Trial., , Journal of the American College of Cardiology, 2020, 10.1016/j.jacc.2020.08.049
  • Live longer and better without aortic valve stenosis., Clavel MA, Pibarot P, Marie-Annick Clavel, DVM, PhD, FACC, FAHA, FCCS, The Lancet. Healthy longevity, 2022, 10.1016/s2666-7568(22)00188-x
  • Angiotensin II receptor blockers are associated with reduced valvular fibrosis in females with aortic stenosis., Clavel MA, Dahl JS, Pibarot P, Dagenais F, Pagé S, Trahan S, Dumont É, Couture C, Demers K, Haujir A, Powers A, Ali M, Le Nezet E, Carter-Storch R, The Canadian journal of cardiology, 2024, 10.1016/j.cjca.2024.03.009
  • Aortic Valve Disease, , Clinical Echocardiography Review: A Self-Assessment Tool, 2nd edition, 2017
  • Effects of Cyproheptadine on Mitral Valve Remodeling and Regurgitation After Myocardial Infarction., Marie-Annick Clavel, DVM, PhD, FACC, FAHA, FCCS, Journal of the American College of Cardiology, 2022, 10.1016/j.jacc.2022.05.025
  • Accuracy of stroke volume measurement with phase-contrast cardiovascular magnetic resonance in patients with aortic stenosis, , Journal of Cardiovascular Magnetic Resonance, 2021, 10.1186/s12968-021-00814-4
  • Hemodynamic and Clinical Outcomes in Redo-Surgical Aortic Valve Replacement vs. Transcatheter Valve-in-Valve, Philippe Pibarot, erwan salaun, Josep Rodés-Cabau, Marie-Annick Clavel, DVM, PhD, FACC, FAHA, FCCS, Siamak Mohammadi, Robert Delarochellière, Dimitri Kalavrouziotis, Eric Dumont, Mathieu Bernier, Kim O’Connor, Jonathan Beaudoin, Jean-Michel Paradis, Leonardo Guimaraes, Nancy Côté, Lionel Tastet, Jérémy Bernard, Anne-Sophie Zenses, Sébastien Hecht, Structural Heart, 2022, 10.1016/j.shj.2022.100106
  • E-Letter-RE: Measurement of aortic valve area: Should we fuse echocardiography and computed tomography to reclassify aortic stenosis severity?, Enriquez-Sarano, M., Pibarot, P., Clavel, M. A., Eur Heart J, 2015
  • Soluble CD14 is associated with the structural failure of bioprostheses., , Clinica chimica acta; international journal of clinical chemistry, 2018, 10.1016/j.cca.2018.06.045
  • Usefulness of global left ventricular longitudinal strain for risk stratification in low ejection fraction, low-gradient aortic stenosis: results from the multicenter True or Pseudo-Severe Aortic Stenosis study., , Circulation. Cardiovascular imaging, 2015, 10.1161/circimaging.114.002117
  • Cleft-like indentations in myxomatous mitral valves by three-dimensional echocardiographic imaging., , Heart (British Cardiac Society), 2015, 10.1136/heartjnl-2014-307016
  • Effect of Regional Upper Septal Hypertrophy on Echocardiographic Assessment of Left Ventricular Mass and Remodeling in Aortic Stenosis., , Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2020, 10.1016/j.echo.2020.08.022
  • Normal-flow low-gradient severe aortic stenosis is a frequent and real entity., , European heart journal cardiovascular Imaging, 2019, 10.1093/ehjci/jez211
  • Sex-Specific Associations of Genetically-Predicted Circulating Lipoprotein(a) and Hepatic LPA Gene Expression Levels with Cardiovascular Outcomes: Mendelian Randomization and Observational Analyses., , Circulation. Genomic and precision medicine, 2021, 10.1161/circgen.120.003271
  • Prosthesis-Patient Mismatch After Transcatheter Aortic Valve Replacement: It Is Neither Rare Nor Benign., , Journal of the American College of Cardiology, 2018, 10.1016/j.jacc.2018.09.045
  • Temporal trends of aortic stenosis and comorbid chronic kidney disease in the province of Quebec, Canada., , Open heart, 2022, 10.1136/openhrt-2021-001923
  • Genetic Variation in LPA, Calcific Aortic Valve Stenosis in Patients Undergoing Cardiac Surgery, and Familial Risk of Aortic Valve Microcalcification., , JAMA cardiology, 2019, 10.1001/jamacardio.2019.1581
  • Association of Left Ventricular Global Longitudinal Strain With Asymptomatic Severe Aortic Stenosis: Natural Course and Prognostic Value., , JAMA cardiology, 2018, 10.1001/jamacardio.2018.2288
  • Feasibility and initial results of percutaneous aortic valve implantation including selection of the transfemoral or transapical approach in patients with severe aortic stenosis., , The American journal of cardiology, 2008, 10.1016/j.amjcard.2008.06.061
  • Biomarkers in Mitral Regurgitation., , Progress in cardiovascular diseases, 2017, 10.1016/j.pcad.2017.11.004
  • Discordant grading of aortic stenosis using echocardiography and what it means: new insights from magnetic resonance imaging., , The Canadian journal of cardiology, 2014, 10.1016/j.cjca.2014.06.007
  • Sex-Related Discordance Between Aortic Valve Calcification and Hemodynamic Severity of Aortic Stenosis: Is Valvular Fibrosis the Explanation?, , Circulation research, 2016, 10.1161/circresaha.116.309306
  • Valve-in-Valve Procedure in Failed Transcatheter Aortic Valves., , JACC. Cardiovascular imaging, 2018, 10.1016/j.jcmg.2018.03.011
  • Valve-in-Valve Transcatheter Aortic Valve Replacement Versus Redo Surgical Aortic Valve Replacement: An Updated Meta-Analysis, , 1911, 10.1016/j.jcin.2020.10.020
  • Sex-related differences in calcific aortic stenosis: correlating clinical and echocardiographic characteristics and computed tomography aortic valve calcium score to excised aortic valve weight., , European heart journal, 2015, 10.1093/eurheartj/ehv560
  • Prevalence and Outcomes of Patients With Discordant High-Gradient Aortic Stenosis., Clavel MA, Xavier Galloo, Lacasse-Rioux E, Le Nezet E, Powers A, Unger P, Journal of the American College of Cardiology, 2024, 10.1016/j.jacc.2024.01.025
  • The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women - Chapter 6: Sex- and Gender-Specific Diagnosis and Treatment., , CJC open, 2022, 10.1016/j.cjco.2022.04.002
  • Aortic Stenosis, , Heart Valve Disease - State of the Art, 2020, 10.1007/978-3-030-23104-0_3
  • Prosthesis-Patient Mismatch After Aortic Valve Replacement in the PARTNER 2 Trial and Registry., , JACC. Cardiovascular interventions, 2021, 10.1016/j.jcin.2021.03.069
  • Reply: Calcium Score to Specify Assessment of Low-Flow Aortic Stenosis Severity., , Journal of the American College of Cardiology, 2021, 10.1016/j.jacc.2021.07.011
  • Usefulness of the energy loss index in the adjudication of low-gradient aortic stenosis severity, Philippe Pibarot, Marie-Annick Clavel, Ezequiel Guzzetti, European Heart Journal - Cardiovascular Imaging, 2020, 10.1093/ehjci/jeaa052
  • Bioprosthetic Mitral Valve Thrombosis: A Multifaceted and Challenging Clinical and Imaging Spectrum., , JACC. Cardiovascular imaging, 2021, 10.1016/j.jcmg.2021.08.023
  • Mixed Aortic Valve Disease: A Diagnostic Challenge, a Prognostic Threat, , Structural Heart, 2020, 10.1080/24748706.2020.1817643
  • Prosthetic Aortic Valve, , Encyclopedia of Biomedical Engineering, 2019, 10.1016/B978-0-12-801238-3.11103-1
  • Dobutamine Stress Echocardiography in Low-Flow, Low-Gradient Aortic Stenosis: Flow Reserve Does Not Matter Anymore., , Journal of the American Heart Association, 2019, 10.1161/JAHA.119.012212
  • Imaging and Impact of Myocardial Fibrosis in Aortic Stenosis., , JACC. Cardiovascular imaging, 2019, 10.1016/j.jcmg.2018.11.026
  • Echocardiographic Assessment of Aortic Stenosis Severity: Do Not Rely on a Single Parameter., , Journal of the American Heart Association, 2016, 10.1161/JAHA.116.004680
  • Circulating levels of matrix gla protein and progression of aortic stenosis: a substudy of the Aortic Stenosis Progression Observation: Measuring Effects of rosuvastatin (ASTRONOMER) trial., , The Canadian journal of cardiology, 2014, 10.1016/j.cjca.2014.03.025
  • Effect of race on pressure recovery adjustment for prevention of aortic stenosis grading discordance, Jae-Kwan Song, Marie-Annick Clavel, DVM, PhD, FACC, FAHA, FCCS, Philippe Pibarot, marc dweck, Duk-Hyun Kang, Jong-Min Song, Dae-Hee Kim, Sahmin Lee, Seung-Ah Lee, Simona Botezatu, Krithika Loganath, Lionel Tastet, Ezequiel Guzzetti, Mylène Shen, Heart, 2023, 10.1136/heartjnl-2023-322586
  • Association of Natriuretic Peptide Levels After Transcatheter Aortic Valve Replacement With Subsequent Clinical Outcomes, , JAMA Cardiology, 2020, 10.1001/jamacardio.2020.2614
  • Performance-based functional assessment of patients undergoing transcatheter aortic valve implantation., , American heart journal, 2011, 10.1016/j.ahj.2010.12.024
  • Concomitant mitral regurgitation: an insidious cause of lowflow, low-gradient severe aortic stenosis., , EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2018, 10.4244/eijv13i14a261
  • Dobutamine Stress Echocardiography in Low-Gradient Aortic Stenosis, Jordi Sanchez Dahl, Marie-Annick Clavel, Philippe Pibarot, Patricia A Pellikka, Kristian Altern Øvrehus, Jacob Eifer Møller, Jasmine Grenier-Delaney, Mohamed-Salah Annabi, Rasmus Carter-Storch, Mulham Ali, Nils Sofus Borg Mogensen, 2023, 10.1101/2023.02.27.23286540
  • Measuring progression of aortic stenosis: computed tomography versus echocardiography., , Heart (British Cardiac Society), 2020, 10.1136/heartjnl-2020-317340
  • Validation and characterization of transcatheter aortic valve effective orifice area measured by Doppler echocardiography., , JACC. Cardiovascular imaging, 2011, 10.1016/j.jcmg.2011.06.021
  • Prognostic utility of N-terminal pro B-type natriuretic peptide ratio in mixed aortic valve disease, Marie-Annick Clavel, Erwan Salaun, Lionel Tastet, Frédéric Jacques, David Bienjonetti-Boudreau, Guillaume Jean, Jérémy Bernard, Open Heart, 2023, 10.1136/openhrt-2023-002361
  • The MIDA Mortality Risk Score: development and external validation of a prognostic model for early and late death in degenerative mitral regurgitation., , European heart journal, 2018, 10.1093/eurheartj/ehx465
  • A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis., , Nature communications, 2018, 10.1038/s41467-018-03260-6
  • Doppler Velocity Index Outcomes Following Surgical or Transcatheter Aortic Valve Replacement in the PARTNER Trials, , JACC: Cardiovascular Interventions, 2021, 10.1016/j.jcin.2021.04.007
  • Why and How to Measure Aortic Valve Calcification in Patients With Aortic Stenosis., , JACC. Cardiovascular imaging, 2019, 10.1016/j.jcmg.2019.01.045
  • Flexibility of microstructural adaptations in airway smooth muscle, , Journal of Applied Physiology, 2021, 10.1152/japplphysiol.00894.2020
  • Impact of Metabolic Syndrome and/or Diabetes Mellitus on Left Ventricular Mass and Remodeling in Patients With Aortic Stenosis Before and After Aortic Valve Replacement., , The American journal of cardiology, 2018, 10.1016/j.amjcard.2018.09.015
  • Impact of mandatory preoperative dental screening on post-procedural risk of infective endocarditis in patients undergoing transcatheter aortic valve implantation: a nationwide retrospective observational study., Jordi Dahl, Clavel MA, Gerke O, Povlsen JA, Freeman P, Andersen NH, Terkelsen CJ, Nissen H, Schødt Riber LP, Krasniqi L, The Lancet regional health. Europe, 2023, 10.1016/j.lanepe.2023.100789
  • Comparison between cardiovascular magnetic resonance and transthoracic Doppler echocardiography for the estimation of effective orifice area in aortic stenosis., , Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2011, 10.1186/1532-429X-13-25
  • MULTI-MODALITY IMAGING IN AORTIC STENOSIS: AN EACVI CLINICAL CONSENSUS DOCUMENT, Erwan Donal, patrizio lancellotti, Marie-Annick Clavel, gilbert habib, Marc R Dweck, 2023, 10.1093/ehjci/jead153
  • Transcatheter Aortic Valve Replacement in Patients With Reduced Ejection Fraction and Nonsevere Aortic Stenosis, Marie-Annick Clavel, DVM, PhD, FACC, FAHA, FCCS, Won-Keun Kim, Ran Kornowski, Nicolas Van Mieghem, Jordi S. Dahl, Augustin Coisne, Walid Ben Ali, Nils Perrin, Benjamin Longère, Mogensen, NSB, Maya Wiessman, Joris Ooms, Bernard Iung, Holger Thiele, Christian W. Hamm, Matthias Renker, Guillaume Jean, Marina Urena, Mohamed Abdel-Wahab, Niklas Schofer, Sebastian Ludwig, Circulation: Cardiovascular Interventions, 2023, 10.1161/circinterventions.122.012768
  • Is there an outcome penalty linked to guideline-based indications for valvular surgery? Early and long-term analysis of patients with organic mitral regurgitation., , The Journal of thoracic and cardiovascular surgery, 2015, 10.1016/j.jtcvs.2015.04.009
  • Sex Differences and Survival in Adults With Bicuspid Aortic Valves: Verification in 3 Contemporary Echocardiographic Cohorts., , Journal of the American Heart Association, 2016, 10.1161/JAHA.116.004211
  • Electrocardiographic changes and clinical outcomes after transapical aortic valve implantation., , American heart journal, 2009, 10.1016/j.ahj.2009.05.029
  • Impact of low flow on the outcome of high-risk patients undergoing transcatheter aortic valve replacement., , Journal of the American College of Cardiology, 2013, 10.1016/j.jacc.2013.05.044
  • Percutaneous Transcatheter Edge-to-Edge Mitral Valve Repair With MitraClip System in the Era of G4., Salaun E, Rodés-Cabau J, Bernier M, Pibarot P, Mohammadi S, Dumont E, Dagenais F, Clavel MA, Gravel C, Mesnier J, Panagides V, Alperi A, Ternacle J, O'Connor K, Beaudoin J, Paradis JM, Turgeon PY, Silva I, Structural heart : the journal of the Heart Team, 2022, 10.1016/j.shj.2022.100114
  • B-type natriuretic peptide clinical activation in aortic stenosis: impact on long-term survival., , Journal of the American College of Cardiology, 2014, 10.1016/j.jacc.2014.02.581
  • Regression of Left Ventricular Mass After Transcatheter Aortic Valve Replacement: The PARTNER Trials and Registries., , Journal of the American College of Cardiology, 2020, 10.1016/j.jacc.2020.03.042
  • Left ventricular outflow tract geometry and dynamics in aortic stenosis: implications for the echocardiographic assessment of aortic valve area., , Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2015, 10.1016/j.echo.2015.09.006
  • The Canadian Women's Heart Health Alliance ATLAS on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women - Chapter 8: Knowledge Gaps and Status of Existing Research Programs in Canada., Norris CM, Mulvagh SL, Mullen KA, Jacques KE, Liu S, Limbachia J, Keeping-Burke L, Adreak N, Gomes Z, Dhukai A, Ahmed S, Colella TJF, Bruneau J, Jaffer S, Cotie L, Kirkham AA, Liblik K, Parry M, Randhawa V, Foulds H, Mantella LE, Van Spall HGC, Clavel MA, CJC open, 2023, 10.1016/j.cjco.2023.11.013
  • Association of Bioprosthetic Aortic Valve Leaflet Calcification on Hemodynamic and Clinical Outcomes., , Journal of the American College of Cardiology, 2020, 10.1016/j.jacc.2020.08.034
  • Bioprosthetic aortic valve durability in the era of transcatheter aortic valve implantation., , Heart (British Cardiac Society), 2018, 10.1136/heartjnl-2017-311582
  • Left ventricular asymmetric remodeling and subclinical left ventricular dysfunction in patients with calcific aortic valve stenosis – Results from a subanalysis of the PROGRESSA study, , International Journal of Cardiology, 2021, 10.1016/j.ijcard.2021.03.017
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  • Impact of Left Ventricular Dysfunction in Patients with High and Low Gradient Severe Aortic Stenosis Following Transcatheter Aortic Valve Replacement., , The Canadian journal of cardiology, 2020, 10.1016/j.cjca.2020.10.014
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  • Stress echocardiography to assess stenosis severity and predict outcome in patients with paradoxical low-flow, low-gradient aortic stenosis and preserved LVEF., , JACC. Cardiovascular imaging, 2013, 10.1016/j.jcmg.2012.10.015
  • RE: Measurement of Aortic Valve Area: Should we fuse Echocardiography and Computed Tomography to Reclassify Aortic Stenosis Severity? - Letter, , European Heart Journal, 2015
  • Lipoprotein(a), Oxidized Phospholipids, and Aortic Valve Microcalcification Assessed by 18F-Sodium Fluoride Positron Emission Tomography and Computed Tomography., , CJC open, 2019, 10.1016/j.cjco.2019.03.004
  • Extracellular Myocardial Volume in Patients With Aortic Stenosis., , Journal of the American College of Cardiology, 2020, 10.1016/j.jacc.2019.11.032
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  • Impact of Aortic Valve Calcification and Sex on Hemodynamic Progression and Clinical Outcomes in AS., , Journal of the American College of Cardiology, 2017, 10.1016/j.jacc.2017.02.037
  • Transcatheter versus surgical valve replacement for a failed pulmonary homograft in the Ross population., , The Journal of thoracic and cardiovascular surgery, 2017, 10.1016/j.jtcvs.2017.10.141
  • Metabolic syndrome is associated with more pronounced impairment of left ventricle geometry and function in patients with calcific aortic stenosis: a substudy of the ASTRONOMER (Aortic Stenosis Progression Observation Measuring Effects of Rosuvastatin)., , Journal of the American College of Cardiology, 2010, 10.1016/j.jacc.2009.11.083
  • Assessment of Aortic Stenosis Severity: A Multimodality Approach., , Cardiology clinics, 2020, 10.1016/j.ccl.2019.09.004
  • Outcome and undertreatment of mitral regurgitation: a community cohort study., , Lancet (London, England), 2018, 10.1016/S0140-6736(18)30473-2
  • Preload Stress Echocardiography: A New Tool to Confirm Severity of Low-Gradient Aortic Stenosis., , Circulation. Cardiovascular imaging, 2017, 10.1161/circimaging.117.007035
  • Haemodynamic outcomes following aortic valve-in-valve procedure., , Open heart, 2018, 10.1136/openhrt-2018-000854
  • Pre- and Post-Operative Stroke Volume Impact After Surgical Aortic Valve Replacement for Severe Aortic Stenosis., , Journal of the American College of Cardiology, 2020, 10.1016/j.jacc.2020.08.060
  • Aortic Valve disease, An Issue of Cardiology Clinics, , Marie-Annick Clavel, Philippe Pibarot, 2019
  • Deleterious variants in DCHS1 are prevalent in sporadic cases of mitral valve prolapse., , Molecular genetics & genomic medicine, 2017, 10.1002/mgg3.347
  • True-Severe or Pseudo-Severe AS? , , 2020
  • Age, Sex, and Valve Phenotype Differences in Fibro-Calcific Remodeling of Calcified Aortic Valve., , Journal of the American Heart Association, 2020, 10.1161/jaha.119.015610
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  • Increasing Pulmonary Arterial Pressure at Low Level of Exercise in Asymptomatic, Organic Mitral Regurgitation., , Journal of the American College of Cardiology, 2018, 10.1016/j.jacc.2017.11.062
  • Predictors of left ventricular ejection fraction recovery following aortic valve replacement in patients with low flow, low gradient, aortic stenosis - The multicenter TOPAS study, Pibarot, P., Rosenhek, R., Sénéchal, M., Mathieu, P., Baumgartner, H., Bergler-Klein, J., Dumesnil, J. G., Burwash, I. G., Mundigler, G., Clavel, M. A., Eur Heart J, 2009
  • Dilemma in the therapeutic management of low-gradient aortic stenosis., , Current opinion in cardiology, 2017, 10.1097/hco.0000000000000374
  • Pathophysiology of Aortic Valve Calcification and Stenosis, , JACC: Cardiovascular Imaging, 2020, 10.1016/j.jcmg.2020.04.024
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  • Cardiovascular Magnetic Resonance to Evaluate Aortic Regurgitation After Transcatheter Aortic Valve Replacement., , Journal of the American College of Cardiology, 2016, 10.1016/j.jacc.2016.05.059
  • Importance of Flow in Risk Stratification of Aortic Stenosis, Philippe Pibarot, Marie-Annick Clavel, Ezequiel Guzzetti, Canadian Journal of Cardiology, 2020, 10.1016/j.cjca.2019.10.020
  • Vascular Burden Impact on Echocardiographic Valvular Graft Degeneration Following a Ross Procedure in Young Adults., , Journal of the American College of Cardiology, 2017, 10.1016/j.jacc.2017.06.042
  • Mid-term clinical and echocardiographic results of the INSPIRIS RESILIA aortic valve: a retrospective comparison to the Magna Ease, Siamak Mohammadi, Dimitri Kalavrouziotis, Shervin Babaki, Marie-Annick Clavel, Philippe Pibarot, Sébastien Hecht, Gabriel Georges, Jérémy Bernard, Interdisciplinary CardioVascular and Thoracic Surgery, 2023, 10.1093/icvts/ivad117
  • B-Type Natriuretic Peptide and High-Sensitivity Cardiac Troponin for Risk Stratification in Low-Flow, Low-Gradient Aortic Stenosis: A Substudy of the TOPAS Study., , JACC. Cardiovascular imaging, 2017, 10.1016/j.jcmg.2017.06.018
  • Staging Cardiac Damage in Patients With Asymptomatic Aortic Valve Stenosis., , Journal of the American College of Cardiology, 2019, 10.1016/j.jacc.2019.04.065
  • Sex-Related Differences in the Extent of Myocardial Fibrosis in Patients With Aortic Valve Stenosis., , JACC. Cardiovascular imaging, 2020, 10.1016/j.jcmg.2019.06.014
  • Effect of age and aortic valve anatomy on calcification and haemodynamic severity of aortic stenosis., , Heart (British Cardiac Society), 2016, 10.1136/heartjnl-2016-309665
  • Left Ventricular Hypertrophy and Clinical Outcomes Over 5 Years After TAVR, , JACC: Cardiovascular Interventions, 2020, 10.1016/j.jcin.2020.03.011
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  • Paravalvular Regurgitation After Transcatheter Aortic Valve Replacement: Is the Problem Solved?, , Interventional cardiology clinics, 2018, 10.1016/j.iccl.2018.06.005
  • Challenges in the diagnosis and Treatment of Low-Flow, Low-Gradient Aortic Stenosis, , Advances and Controversies in Adult Heart Valve Surgery, 2013
  • Biomarkers of aortic bioprosthetic valve structural degeneration., , Current opinion in cardiology, 2019, 10.1097/hco.0000000000000590
  • Apical aortic valve implantation in a patient with a mechanical valve prosthesis in mitral position., , Circulation. Cardiovascular interventions, 2008, 10.1161/circinterventions.108.813592
  • Severe valvular regurgitation and late prosthesis embolization after percutaneous aortic valve implantation., , The Annals of thoracic surgery, 2009, 10.1016/j.athoracsur.2008.06.059
  • Usefulness of the B-Type Natriuretic Peptides in Low Ejection Fraction, Low-Flow, Low-Gradient Aortic Stenosis Results from the TOPAS Multicenter Prospective Cohort Study, Clavel, M.-A., Pibarot, P., Rodès-Cabau, J., Ribeiro, H.B., Cavalcante, J., Mundigler, G., Mascherbauer, J., Koschutnik, M., Bartko, P.E., Baumgartner, H., Orwat, S., Tastet, L., Ong, G., Guzzetti, E., Burwash, I.G., Dahou, A., Bergler-Klein, J., Zhang, B., Annabi, M.-S., Structural Heart, 2021, 10.1080/24748706.2021.1900630
  • Outcome of Flow-Gradient Patterns of Aortic Stenosis After Aortic Valve Replacement, , Circulation: Cardiovascular Interventions, 2020, 10.1161/circinterventions.119.008792
  • Impact of Vascular Hemodynamics on Aortic Stenosis Evaluation: New Insights Into the Pathophysiology of Normal Flow-Small Aortic Valve Area-Low Gradient Pattern., , Journal of the American Heart Association, 2017, 10.1161/JAHA.117.006276
  • Sex Differences in the Pathophysiology, Diagnosis, and Management of Aortic Stenosis., , Cardiology clinics, 2020, 10.1016/j.ccl.2019.09.008
  • Calcific Aortic Valve Stenosis and Atherosclerotic Calcification., , Current atherosclerosis reports, 2020, 10.1007/s11883-020-0821-7
  • Effect of bicuspid aortic valve phenotype on progression of aortic stenosis., , European heart journal cardiovascular Imaging, 2020, 10.1093/ehjci/jeaa068
  • Unique Aspects of Women's Valvular Heart Diseases: Impact for Diagnosis and Treatment., Clavel MA, Le Nezet E, Lavoie N, Powers A, CJC open, 2023, 10.1016/j.cjco.2023.10.017
  • Progression of aortic stenosis after an acute myocardial infarction., , Open heart, 2022, 10.1136/openhrt-2022-002046
  • Prognostic Value of N-Terminal Pro-B-Type Natriuretic Peptide in Elderly Patients With Valvular Heart Disease. , , Journal of the American College of Cardiology, 2020, 10.1016/j.jacc.2020.02.031
  • Discordant Grading of Aortic Stenosis Severity: New Insights from an In Vitro Study, Régis Rieu, Philippe Pibarot, Gilbert Habib, Guillaume Penaranda, Paul Barragan, Marie-Annick Clavel, Anne-Sophie Zenses, Viktoria Stanova, Jérôme Adda, Structural Heart, 2019, 10.1080/24748706.2019.1632507
  • Balloon aortic valvuloplasty as a palliative treatment in patients with severe aortic stenosis and limited life expectancy: a single center experience., , Aging, 2020, 10.18632/aging.103862
  • Lipoprotein-associated phospholipase A2 activity, genetics and calcific aortic valve stenosis in humans, , Heart, 2020, 10.1136/heartjnl-2020-316722
  • Midterm Survival of Low‐Risk Patients Treated With Transcatheter Versus Surgical Aortic Valve Replacement: Meta‐Analysis of Reconstructed Time‐to‐Event Data, Ibrahim Sultan, Philippe Pibarot, Marie‐Annick Clavel, Danny Chu, Derek Serna‐Gallegos, Jef Van den Eynde, Xander Jacquemyn, Michel Pompeu Sá, Journal of the American Heart Association, 2023, 10.1161/JAHA.123.030012
  • Multimodality Imaging for Discordant Low-Gradient Aortic Stenosis: Assessing the Valve and the Myocardium, , Frontiers in Cardiovascular Medicine, 2020, 10.3389/fcvm.2020.570689
  • Effect of Recurrent Mitral Regurgitation Following Degenerative Mitral Valve Repair: Long-Term Analysis of Competing Outcomes., , Journal of the American College of Cardiology, 2016, 10.1016/j.jacc.2015.10.098
  • Chronic Kidney Disease and the Pathophysiology of Valvular Heart Disease., , The Canadian journal of cardiology, 2019, 10.1016/j.cjca.2019.05.028
  • Low-Flow-Low Gradient, Clinical implications, Time of Surgery, , Valvular Heart Disease, 2016
  • Discordant Echocardiographic Grading in Low Gradient Aortic Stenosis (DEGAS Study) From the Italian Society of Echocardiography and Cardiovascular Imaging Research Network: Rationale and Study Design., , Journal of cardiovascular echography, 2020, 10.4103/jcecho.jcecho_68_20
  • Outcome and Impact of Aortic Valve Replacement in Patients With Preserved LVEF and Low-Gradient Aortic Stenosis., , Journal of the American College of Cardiology, 2015, 10.1016/j.jacc.2015.09.076
  • A Machine-Learning Framework to Identify Distinct Phenotypes of Aortic Stenosis Severity, , JACC: Cardiovascular Imaging, 2021, 10.1016/j.jcmg.2021.03.020
  • Long-term prognostic value and serial changes of plasma N-terminal prohormone B-type natriuretic peptide in patients undergoing transcatheter aortic valve implantation., , The American journal of cardiology, 2013, 10.1016/j.amjcard.2013.11.038
  • Impact of sex on the management and outcome of aortic stenosis patients, , European Heart Journal, 2021, 10.1093/eurheartj/ehab242
  • Three-Dimensional Echocardiography: A Powerful New Tool in the Evaluation of Mitral Annular Structure and Dynamics., , Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2015, 10.1016/j.echo.2015.07.020
  • Reclassification of prosthesis–patient mismatch after transcatheter aortic valve replacement using predicted vs. measured indexed effective orifice area, , European Heart Journal - Cardiovascular Imaging, 2020, 10.1093/ehjci/jeaa235
  • Acute kidney injury following transcatheter aortic valve implantation: predictive factors, prognostic value, and comparison with surgical aortic valve replacement., , European heart journal, 2009, 10.1093/eurheartj/ehp552
  • Sex-Related Differences in Low-Gradient, Low-Ejection Fraction Aortic Stenosis: Results From the Multicenter TOPAS Study., , JACC. Cardiovascular imaging, 2019, 10.1016/j.jcmg.2018.11.003
  • Performance of Computed Tomographic Angiography–Based Aortic Valve Area for Assessment of Aortic Stenosis, Prabhjot S. Nijjar, Sue Duval, Philippe Pibarot, Marie‐Annick Clavel, Dzhalal Agakishiev, Jose Arriola‐Montenegro, Gurmandeep S. Sandhu, Jerry Ash, Journal of the American Heart Association, 2023, 10.1161/JAHA.123.029973
  • Integrative genomic analyses identify candidate causal genes for calcific aortic valve stenosis involving tissue-specific regulation., Yohan Bossé, Esko T, Patrick Mathieu, Nicholas Wareham, Boekholdt SM, Benoit Arsenault, Pibarot P, Marie-Annick Clavel, DVM, PhD, FACC, FAHA, FCCS, Dagenais F, Dahmene M, Argaud D, Frenette L, Nathalie Gaudreault, Dominique K. Boudreau, Estonian Biobank Research Team, BRIEND mewen, Zamani P, Ursula Houessou, Hasanga Dilshan Manikpurage, Jian'an Luan, Erik Abner, Zhonglin LI, Sébastien Thériault, Nature communications, 2024, 10.1038/s41467-024-46639-4
  • Early benefits of bariatric surgery on subclinical cardiac function: Contribution of visceral fat mobilization, , Metabolism, 2021, 10.1016/j.metabol.2021.154773
  • State of the Science in Women's Cardiovascular Disease: A Canadian Perspective on the Influence of Sex and Gender., , Journal of the American Heart Association, 2020, 10.1161/jaha.119.015634
  • Multiparametric Approach for the Assessment of Mechanical Prosthetic Tricuspid Leaflet Function., , Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2021, 10.1016/j.echo.2021.09.001
  • Mitral Effective Regurgitant Orifice Area Predicts Pulmonary Artery Pressure Level in Patients with Aortic Valve Stenosis., , Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2018, 10.1016/j.echo.2017.12.004
  • Sex differences in aortic valve calcification measured by multidetector computed tomography in aortic stenosis., , Circulation. Cardiovascular imaging, 2012, 10.1161/circimaging.112.980052
  • Bone Mineral Density and Progression Rate of Calcific Aortic Valve Stenosis. , , Journal of the American College of Cardiology, 2020, 10.1016/j.jacc.2020.01.053
  • Blood, tissue and imaging biomarkers in calcific aortic valve stenosis: past, present and future., , Current opinion in cardiology, 2018, 10.1097/hco.0000000000000487
  • Impact of Prosthesis-Patient Mismatch After Surgical Aortic Valve Replacement: Systematic Review and Meta-Analysis of Reconstructed Time-to-Event Data of 122 989 Patients With 592 952 Patient-Years., Ibrahim Sultan, Philippe Pibarot, Marie-Annick Clavel, DVM, PhD, FACC, FAHA, FCCS, Tjark Ebels, Derek Serna-Gallegos, Danny Chu, Jef Van den Eynde, Xander Jacquemyn, Michel Pompeu Sá, Journal of the American Heart Association, 2024, 10.1161/jaha.123.033176
  • Dynamic phenotypes of degenerative myxomatous mitral valve disease: quantitative 3-dimensional echocardiographic study., , Circulation. Cardiovascular imaging, 2015, 10.1161/circimaging.114.002989
  • Prognostic Implications of Moderate Aortic Stenosis in Patients With Left Ventricular Systolic Dysfunction., , Journal of the American College of Cardiology, 2017, 10.1016/j.jacc.2017.03.023
  • Case Report: Posterior Thoracic Window in the Presence of Pleural Effusion in Critical Care Medicine: One More Chance to Image the Aortic Valve., , Frontiers in cardiovascular medicine, 2022, 10.3389/fcvm.2022.907168
  • Genetic and In Vitro Inhibition of PCSK9 and Calcific Aortic Valve Stenosis, , JACC: Basic to Translational Science, 2020, 10.1016/j.jacbts.2020.05.004
  • Computed Tomography Aortic Valve Calcium Scoring in Patients With Bicuspid Aortic Valve Stenosis., Pibarot P, Song JK, Brito D, Pressman G, Tay E, Kong W, Poh KK, Perez de Arenaza D, Falconi ML, Mando R, Abbas AE, Dweck MR, Bax JJ, Delgado V, Clavel MA, Tastet L, Pawade T, Singh GK, Guzzetti E, Oh JK, Shen M, Structural heart : the journal of the Heart Team, 2022, 10.1016/j.shj.2022.100027
  • Oral Anticoagulation Therapy and Progression of Calcific Aortic Valve Stenosis., , Journal of the American College of Cardiology, 2019, 10.1016/j.jacc.2019.01.043
  • Cardiac Damage Staging Classification in Asymptomatic Moderate or Severe Primary Mitral Regurgitation., Pibarot P, Maréchaux S, Beaudoin J, Bernier M, O'Connor K, Tartar J, Dumortier H, Clavel MA, Côté N, Tastet L, Mahjoub H, Toubal O, Dupuis M, Altes A, Bernard J, Structural heart : the journal of the Heart Team, 2022, 10.1016/j.shj.2022.100004
  • Catheter-Induced Postextrasystolic Potentiation in the Assessment of Severity of Low-Gradient Aortic Valve Stenosis, Philippe Pibarot, Marie-Annick Clavel, John G. Webb, Jay S. Shavadia, Rodney H. Zimmermann, Andrea J. Lavoie, Jeffrey Booker, Zachary Singer, Jyotpal Singh, Payam Dehghani, Circulation: Cardiovascular Interventions, 2023, 10.1161/CIRCINTERVENTIONS.123.012892
  • Comparison between transcatheter and surgical prosthetic valve implantation in patients with severe aortic stenosis and reduced left ventricular ejection fraction., , Circulation, 2010, 10.1161/circulationaha.109.929893
  • Immediate Outcomes of Aortic Valve Neocuspidization with Glutaraldehyde-treated Autologous Pericardium: a Multicenter Study, , Brazilian Journal of Cardiovascular Surgery, 2020, 10.21470/1678-9741-2020-0019
  • Evolution of the burden of aortic stenosis by sex in the province of Quebec between 2006 and 2018., , Heart (British Cardiac Society), 2022, 10.1136/heartjnl-2021-319848
  • Shortening of airway smooth muscle is modulated by prolonging the time without simulated deep inspirations in ovine tracheal strips., , Journal of applied physiology (Bethesda, Md. : 1985), 2019, 10.1152/japplphysiol.00423.2019
  • Impact of valvuloarterial impedance on 2-year outcome of patients undergoing transcatheter aortic valve implantation., , Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2013, 10.1016/j.echo.2013.04.003
  • Rate, Timing, Correlates, and Outcomes of Hemodynamic Valve Deterioration After Bioprosthetic Surgical Aortic Valve Replacement., , Circulation, 2018, 10.1161/circulationaha.118.035150
  • Echocardiographic Variables Associated with Transvalvular Gradient after a Transcatheter Edge-to-Edge Mitral Valve Repair., , Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2021, 10.1016/j.echo.2021.09.015
  • Doppler Echocardiographic Quantitation of Aortic Valve Stenosis: A Science in Constant Evolution., , Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2016, 10.1016/j.echo.2016.08.015
  • Reply: Comparison of Echocardiography and CT for the Assessment of Aortic Stenosis Valve Area., , JACC. Cardiovascular imaging, 2015, 10.1016/j.jcmg.2015.05.005
  • Concomitant mitral regurgitation and aortic stenosis: one step further to low-flow preserved ejection fraction aortic stenosis., , European heart journal cardiovascular Imaging, 2018, 10.1093/ehjci/jex172
  • Arrhythmic Risk Following Recovery of Left Ventricular Ejection Fraction in Patients with Primary Prevention ICD., , Pacing and clinical electrophysiology : PACE, 2016, 10.1111/pace.12868
  • Severe and Asymptomatic Aortic Stenosis Management Challenge: Knowing That We Do Not Really Know., , Current treatment options in cardiovascular medicine, 2017, 10.1007/s11936-017-0533-7
  • Implications of Left Ventricular Geometry in Low-Flow Aortic Stenosis: A PARTNER 2 Trial Subanalysis., , JACC. Cardiovascular imaging, 2018, 10.1016/j.jcmg.2018.10.019
  • Computed tomography calcium scoring in aortic stenosis: bicuspid versus tricuspid morphology, Hector I Michelena, Maurice Enriquez-Sarano, Philippe Pibarot, Thomas A Foley, Marie-Annick Clavel, Zi Ye, Heart, 2024, 10.1136/heartjnl-2023-323281
  • Erratum: Effect of Recurrent Mitral Regurgitation Following Degenerative Mitral Valve Repair: Long-Term Analysis of Competing Outcomes (Journal of the American College of Cardiology (2016) 67 (488-498)), Enriquez-Sarano, M., Nishimura, R.A., Huebner, M., Michelena, H.I., Schaff, H.V., Clavel, M.-A., Suri, R.M., Journal of the American College of Cardiology, 2016, 10.1016/j.jacc.2016.02.034
  • Aortic Stenosis and Cardiac Amyloidosis: Watch Out for Traps!, Clavel, M.-A., Pibarot, P., Ternacle, J., JACC: Case Reports, 2020, 10.1016/j.jaccas.2020.10.011
  • The Role of Imaging in Measuring Disease Progression and Assessing Novel Therapies in Aortic Stenosis., , JACC. Cardiovascular imaging, 2019, 10.1016/j.jcmg.2018.10.023
  • Visceral adiposity and left ventricular mass and function in patients with aortic stenosis: the PROGRESSA study., , The Canadian journal of cardiology, 2014, 10.1016/j.cjca.2014.02.007
  • REPLY: To PMID 22657269 (Outcome of patients with aortic stenosis, small valve area and low-flow, low-gradient despite preserved left ventricular ejection fraction), Pibarot, P., Sénéchal, M., Mathieu, P., Capoulade, R., Dumesnil, J. G., Clavel, M. A., J Am Coll Cardiol, 2013
  • Reply: Inconsistency of Hemodynamic Data in Low-Gradient Severe Aortic Stenosis: Paradoxical Low-Gradient Aortic Stenosis: The HFpEF of Aortic Stenosis., , Journal of the American College of Cardiology, 2016, 10.1016/j.jacc.2016.02.069
  • Sex Differences in the Progression of Aortic Valve Calcification and Clinical Outcomes: The PROGRESSA Study., , JACC. Cardiovascular imaging, 2022, 10.1016/j.jcmg.2022.02.015
  • Aortic Stenosis and Cardiac Amyloidosis: JACC Review Topic of the Week., , Journal of the American College of Cardiology, 2019, 10.1016/j.jacc.2019.09.056
  • Cardiac Imaging for Assessing Low-Gradient Severe Aortic Stenosis., , JACC. Cardiovascular imaging, 2017, 10.1016/j.jcmg.2017.01.002
  • Hemodynamic changes during aortic valve surgery among patients with aortic stenosis., , Scandinavian cardiovascular journal : SCJ, 2022, 10.1080/14017431.2022.2099008
  • Multimarker Approach to Identify Patients With Higher Mortality and Rehospitalization Rate After Surgical Aortic Valve Replacement for Aortic Stenosis., , JACC. Cardiovascular interventions, 2018, 10.1016/j.jcin.2018.07.039
  • Systolic hypertension and progression of aortic valve calcification in patients with aortic stenosis: results from the PROGRESSA study., , European heart journal cardiovascular Imaging, 2016, 10.1093/ehjci/jew013
  • Progression of Hypertrophy and Myocardial Fibrosis in Aortic Stenosis: A Multicenter Cardiac Magnetic Resonance Study., , Circulation. Cardiovascular imaging, 2018, 10.1161/CIRCIMAGING.117.007451
  • Stress exercise haemodynamic performance and opening reserve of a stented bovine pericardial aortic valve bioprosthesis., , Journal of cardiac surgery, 2022, 10.1111/jocs.16220
  • Response to letters regarding article, "Comparison between transcatheter and surgical prosthetic valve implantation in patients with severe aortic stenosis and reduced left ventricular ejection fraction", Pibarot, P., Mathieu, P., Gurvitch, R., Bergler-Klein, J., Bagur, R., Kempny, A., Moss, R., Mundigler, G., Dumesnil, J. G., Burwash, I. G., Baumgartner, H., Bergeron, S., Doyle, D., De Larochellière, R., Dumont, É, Masson, J. B., Rodés-Cabau, J., Webb, J. G., Clavel, M. A., Circulation, 2011, 10.1161/CIRCULATIONAHA.111.032946
  • Association Between Early Left Ventricular Ejection Fraction Improvement After Transcatheter Aortic Valve Replacement and 5-Year Clinical Outcomes., Marie-Annick Clavel, DVM, PhD, FACC, FAHA, FCCS, JAMA cardiology, 2022, 10.1001/jamacardio.2022.2222
  • Correlates of Coronary Artery Calcification Prevalence and Severity in Patients With Heterozygous Familial Hypercholesterolemia, , 1911
  • Association Between Remnant Cholesterol and Progression of Bioprosthetic Valve Degeneration, Philippe Pibarot, Patrick Mathieu, Marie-Annick Clavel, 2023, 10.1093/ehjci/jead159
  • Underestimation of Aortic Stenosis Severity by Doppler Mean Gradient During Atrial Fibrillation: Insights from Aortic Valve Weight., Nkomo VT, Maleszewski JJ, Pellikka PA, Clavel MA, Negrotto SM, Greason KL, Pislaru SV, El-Am E, Naser JA, Thaden JJ, Alkurashi AK, Marie-Annick Clavel, DVM, PhD, FACC, FAHA, FCCS, Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2022, 10.1016/j.echo.2022.10.007
  • The Canadian Women's Heart Health Alliance ATLAS on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women—Chapter 2: Scope of the Problem, Norris, C.M., Mulvagh, S.L., Yip, C.Y.Y., Mullen, K.A., Clavel, M.-A., Pacheco, C., Gonsalves, C.A., Parry, M., Foulds, H.J.A., Jaffer, S., CJC Open, 2021, 10.1016/j.cjco.2020.10.009
  • Workup and Management of Patients With Paradoxical Low-Flow, Low-Gradient Aortic Stenosis., , Current treatment options in cardiovascular medicine, 2018, 10.1007/s11936-018-0642-y
  • Long-Term Outcomes of Ross Procedure versus Mechanical Aortic Valve Replacement: Meta-Analysis of Reconstructed Time-To-Event Data., , Trends in cardiovascular medicine, 2022, 10.1016/j.tcm.2022.06.005
  • Patient and procedure selection for the prevention of prosthesis-patient mismatch following aortic valve replacement., , EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2015, 10.4244/eijv11swa31
  • Myocardial injury following transcatheter aortic valve implantation: insights from delayed-enhancement cardiovascular magnetic resonance., , EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2015, 10.4244/eijv11i2a39
  • Surgical aortic valve replacement and patient-prosthesis mismatch: a meta-analysis of 108 182 patients., , European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2019, 10.1093/ejcts/ezy466
  • Assessment of low-flow, low-gradient aortic stenosis: multimodality imaging is the key to success., , EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2014, 10.4244/eijv10sua8
  • The Canadian Women's Heart Health Alliance ATLAS on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women - Chapter 9: Summary of Current Status, Challenges, Opportunities, and Recommendations., Norris CM, Mullen KA, Limbachia JA, Wright SP, Nerenberg KA, Van Spall HGC, Iwegim C, Sarfi H, Gomes Z, Parry M, Boivin-Proulx LA, Adreak N, Parast N, Tegg N, Benham JL, Pike A, Robert H, Tulloch H, Bouchard K, Grace SL, Van Damme A, Liblik K, Foulds H, Kirkham AA, Hill B, Clavel MA, Mensour E, Cotie L, Jaffer S, Pacheco C, Bruneau J, Randhawa VK, Allana S, Crosier R, Gulati M, Colella TJF, Mulvagh SL, CJC open, 2023, 10.1016/j.cjco.2023.12.001
  • Attenuated Mitral Leaflet Enlargement Contributes to Functional Mitral Regurgitation After Myocardial Infarction., , Journal of the American College of Cardiology, 2020, 10.1016/j.jacc.2019.11.039
  • Sex-differences in echocardiographic assessment of aortic valve in young adult LDLr-/-/ApoB100/100/IGF-II+/- mice., , Experimental gerontology, 2020, 10.1016/j.exger.2020.111075
  • Impact of surgical aortic root enlargement on the outcomes of aortic valve replacement: a meta-analysis of 13 174 patients., , Interactive cardiovascular and thoracic surgery, 2019, 10.1093/icvts/ivy364
  • How does CT Fit Into the Evaluation and Management of Patients With AS ?, , American Journal of Cardiology, 2016
  • Tricuspid Regurgitation Is Associated With Increased Risk of Mortality in Patients With Low-Flow Low-Gradient Aortic Stenosis and Reduced Ejection Fraction: Results of the Multicenter TOPAS Study (True or Pseudo-Severe Aortic Stenosis)., , JACC. Cardiovascular interventions, 2015, 10.1016/j.jcin.2014.08.019
  • Estimation of Stroke Volume and Aortic Valve Area in Patients with Aortic Stenosis: A Comparison of Echocardiography versus Cardiovascular Magnetic Resonance., , Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2020, 10.1016/j.echo.2020.03.020
  • Impact of metabolic syndrome on progression of aortic stenosis: influence of age and statin therapy., , Journal of the American College of Cardiology, 2012, 10.1016/j.jacc.2012.03.052
  • Moderate Aortic Stenosis in Patients With Heart Failure and Reduced Ejection Fraction, , Journal of the American College of Cardiology, 2021, 10.1016/j.jacc.2021.04.014
  • Outcomes of Patients With Asymptomatic Aortic Stenosis Followed Up in Heart Valve Clinics., , JAMA cardiology, 2018, 10.1001/jamacardio.2018.3152
  • Management of paradoxical low-flow, low-gradient aortic stenosis: need for an integrated approach, including assessment of symptoms, hypertension, and stenosis severity., , Journal of the American College of Cardiology, 2015, 10.1016/j.jacc.2014.10.030
  • Right ventricular longitudinal strain for risk stratification in low-flow, low-gradient aortic stenosis with low ejection fraction., , Heart (British Cardiac Society), 2016, 10.1136/heartjnl-2015-308309
  • Response by Simard et al to Letter Regarding Article, "Sex-Related Discordance Between Aortic Valve Calcification and Hemodynamic Severity of Aortic Stenosis: Is Valvular Fibrosis the Explanation?", , Circulation research, 2017, 10.1161/circresaha.117.310532
  • Reply, Marie-Annick Clavel, DVM, PhD, FACC, FAHA, FCCS, Phillipe Pibarot, Jef Van den Eynde, Xander Jacquemyn, Michel Pompeu Sá, JACC: Cardiovascular Imaging, 2023, 10.1016/j.jcmg.2023.06.015
  • Haemodynamic and anatomic progression of aortic stenosis., , Heart (British Cardiac Society), 2015, 10.1136/heartjnl-2014-307154
  • Outcome of aortic valve replacement in aortic stenosis: the number of valve cusps matters., , European heart journal cardiovascular Imaging, 2018, 10.1093/ehjci/jex258
  • Multiplanar “En Face” Reconstruction of the Aortic Valve, , JACC: Cardiovascular Imaging, 2020, 10.1016/j.jcmg.2020.05.021
  • Sex-related Differences in Calcific Aortic Valve Stenosis: Pathophysiology, Epidemiology, Etiology, Diagnosis, Presentation, and Outcomes, , Structural Heart, 2018, 10.1080/24748706.2017.1420273
  • Calcium Scoring to Classify Aortic Valve Stenosis Severity: What Is the Current Data?, Marie-Annick Clavel, Andréanne Powers, Current Cardiology Reports, 2023, 10.1007/s11886-023-01929-z
  • Correlates of Coronary Artery Calcification Prevalence and Severity in Patients With Heterozygous Familial Hypercholesterolemia, Couture, P., Larose, É., Pibarot, P., Arsenault, B.J., Clisson, M., Clavel, M.-A., Gagnon, A., Godbout, D., Tremblay, A.J., Drouin-Chartier, J.-P., CJC Open, 2021, 10.1016/j.cjco.2020.09.010
  • The complex nature of discordant severe calcified aortic valve disease grading: new insights from combined Doppler echocardiographic and computed tomographic study., , Journal of the American College of Cardiology, 2013, 10.1016/j.jacc.2013.08.1621
  • Validation of conventional and simplified methods to calculate projected valve area at normal flow rate in patients with low flow, low gradient aortic stenosis: the multicenter TOPAS (True or Pseudo Severe Aortic Stenosis) study., , Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2010, 10.1016/j.echo.2010.02.002
  • Calcific aortic stenosis., , Nature reviews. Disease primers, 2016, 10.1038/nrdp.2016.6
  • Coaptation Length as Predictor of Recurrent Mitral Regurgitation After Surgical Repair for Degenerative Mitral Valve Disease: Meta-Analysis of Reconstructed Time-to-Event Data., Goldman S, Ramlawi B, Rodriguez R, Pibarot P, Clavel MA, Borger MA, Marin-Cuartas M, Doenst T, Caldonazo T, Erten O, Van den Eynde J, Jacquemyn X, Sá MP, Structural heart : the journal of the Heart Team, 2023, 10.1016/j.shj.2022.100152
  • Aortic valve area calculation in aortic stenosis by CT and Doppler echocardiography., , JACC. Cardiovascular imaging, 2015, 10.1016/j.jcmg.2015.01.009
  • Early Aortic Valve Replacement versus Watchful Waiting in Asymptomatic Severe Aortic Stenosis: A Study-Level Meta-Analysis, Ricardo C. Lima, Philippe Pibarot, Marie-Annick Clavel, Matheus Simonato, Álvaro M. Perazzo, Antônio C.A. Escorel Neto, Luiz Rafael P. Cavalcanti, Michel Pompeu B.O. Sá, Structural Heart, 2019, 10.1080/24748706.2019.1652946
  • Autotaxin interacts with lipoprotein(a) and oxidized phospholipids in predicting the risk of calcific aortic valve stenosis in patients with coronary artery disease., , Journal of internal medicine, 2016, 10.1111/joim.12519
  • Impact of Right Ventricle-Pulmonary Artery Coupling on Clinical Outcomes in the PARTNER 3 Trial., Hahn RT, Mack MJ, Leon MB, Kodali S, Alu MC, Makkar R, Leipsic J, Khalique OK, Pamela Douglas, Clavel MA, Blanke P, Babaliaros V, Yu X, Pibarot P, Cahill TJ, Marie-Annick Clavel, DVM, PhD, FACC, FAHA, FCCS, JACC. Cardiovascular interventions, 2022, 10.1016/j.jcin.2022.07.005
  • Impact of left ventricular remodelling patterns on outcomes in patients with aortic stenosis., , European heart journal cardiovascular Imaging, 2017, 10.1093/ehjci/jew288
  • Outcome of patients with aortic stenosis, small valve area, and low-flow, low-gradient despite preserved left ventricular ejection fraction., , Journal of the American College of Cardiology, 2012, 10.1016/j.jacc.2011.12.054
  • Clinical vignette: paradoxical low flow, low gradient aortic stenosis despite preserved LV ejection fraction., , Archives of cardiovascular diseases, 2008, 10.1016/j.acvd.2008.08.004
  • Sex and Race Differences in the Pathophysiology, Diagnosis, Treatment, and Outcomes of Valvular Heart Diseases, , Canadian Journal of Cardiology, 2021, 10.1016/j.cjca.2021.02.003
  • Timing of intervention in aortic stenosis: a review of current and future strategies., , Heart (British Cardiac Society), 2018, 10.1136/heartjnl-2017-312304
  • Optimization of Doppler echocardiographic velocity measurements using an automatic contour detection method., , Ultrasound in medicine & biology, 2010, 10.1016/j.ultrasmedbio.2010.05.021
  • Association of B-Type Natriuretic Peptide With Survival in Patients With Degenerative Mitral Regurgitation., , Journal of the American College of Cardiology, 2016, 10.1016/j.jacc.2016.06.047
  • Study Design of the Prospective Non-Randomized Single-Arm Multicenter Evaluation of the Durability of Aortic Bioprosthetic Valves with RESILIA Tissue in Subjects under 65 Years Old (RESILIENCE Trial), Vinod H. Thourani, Lars G. Svensson, Joseph E. Bavaria, Bartley Griffith, Marie-Annick Clavel, Michael A. Borger, Philippe Pibarot, Structural Heart, 2020, 10.1080/24748706.2019.1686554
  • Airway smooth muscle adapting in dynamic conditions is refractory to the bronchodilator effect of a deep inspiration., , American journal of physiology. Lung cellular and molecular physiology, 2020, 10.1152/ajplung.00270.2019
  • Markers of Myocardial Damage Predict Mortality in Patients With Aortic Stenosis., , Journal of the American College of Cardiology, 2021, 10.1016/j.jacc.2021.05.047
  • Validation of aortic valve calcium quantification thresholds measured by computed tomography in Asian patients with calcific aortic stenosis, , European Heart Journal - Cardiovascular Imaging, 2021, 10.1093/ehjci/jeab116
  • Paradoxical low-flow, low-gradient aortic stenosis despite preserved left ventricular ejection fraction: new insights from weights of operatively excised aortic valves., , European heart journal, 2014, 10.1093/eurheartj/ehu152
  • Comprehensive myocardial characterization using cardiac magnetic resonance associates with outcomes in low gradient severe aortic stenosis., , European heart journal. Cardiovascular Imaging, 2022, 10.1093/ehjci/jeac089

Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2009
  • Kathia Abdoun - Doctorat - En cours
  • Chloé Nathalie Nadège Marqueze Pouey - Maîtrise avec mémoire - En cours
  • Najib Ouidadi - Maîtrise avec mémoire - En cours
  • Sébastien Hecht - Maîtrise avec mémoire - En cours
  • Paolo Springhetti - Post-doctorat - En cours
  • Jérémy Bernard - Doctorat - En cours
  • Amélie Paquin - Doctorat - En cours
  • Maxime Berthelot Richer - Maîtrise avec mémoire - 2015/05
  • Lionel Tastet - Maîtrise avec mémoire - 2016/01
  • Mylène Shen - Maîtrise avec mémoire - 2016/05
  • Abdellaziz Dahou - Doctorat - 2017/09
  • Mohamed Salah Annabi - Maîtrise avec mémoire - 2018/09
  • Louis Simard - Maîtrise avec mémoire - 2019/05
  • Saliha Addour - Maîtrise avec mémoire - 2020/05
  • Marine Clisson - Maîtrise avec mémoire - 2020/09
  • Philipp Frieden - Maîtrise avec mémoire - 2020/09
  • Jasmine Grenier Delaney - Maîtrise avec mémoire - 2020/09
  • Macarena Yamila López González - Maîtrise avec mémoire - 2021/09
  • Gabrielle Hudon - Maîtrise avec mémoire - 2023/09

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*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.