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Centre de recherche du CHU de Québec - Université Laval
Partager la fiche :
Contribution à la recherche
Axe de recherche de l'Université Laval :
Santé et bien-être durables
Thématiques de recherche de la Faculté de
médecine :
Immunologie-infectiologie
Domaines et intérêts de recherche du (de la)
professeur(e) :
Maladies infectieuses et immunitaires
Immunodéficiences
Infections virales
Défense cellulaire
Maladies du système immunitaire
Maladies infectieuses
Système immunitaire
Leucocytes
Virus
Thérapie génique des maladies infectueuses et immunitaires
Thérapie cellulaire des maladies infectieuses et immunitaires
Maladies transmises sexuellement
Maladies auto-immunes
Projets de recherche
Fonds institutionnel d'exploitation des infrastructures pour l'Université Laval- Fondation Canadienne pour l'innovation (La) - Fonds d'exploitation des infrastructures (FEI), co-chercheur - 2002-04-01 au 2025-03-31
Deciphering the role of DCIR in HIV-1 pathogenesis- Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2018-04-01 au 2023-03-31
Surveillance des réponses immunitaires au vaccin contre la COVID-19 chez les personnes vivant avec le VIH-1- Instituts de recherche en santé du Canada - Subvention de fonctionnement:Nouveaux besoins prioritaires en recherche sur la COVID-19, chercheur principal - 2021-12-01 au 2022-11-30
Immunité cellulaire et séroprévalence des anticorps contre SARS-COV-2: Caratérisation de trois populations de travailleurs de l'alimentation- Agence de la santé publique du Canada, co-chercheur - 2020-11-01 au 2022-03-31
Discovery of Novel Extracellular Vesicle Biomarkers for the Early Detection of Alzheimer's Disease- Secrétariat des programmes interorganismes à l’intention des établissements - Nouvelles frontières en recherche, Université d'Ottawa, co-chercheur - 2020-03-31 au 2022-03-30
Un banc de test à haute sensibilité pour mesurer la diffusion de virus à travers les matériaux constituant les équipements de protection individuels (gants)- Institut de recherche Robert-Sauvé en santé & sécurité du travail - COVID19 et santé et sécurité au travail, co-chercheur - 2020-09-21 au 2021-09-21
Efficacité in vivo de quatre antagonistes du DCIR à limiter l’infection par le VIH-1- Fondation du CHU de Québec, Ministère de l'Économie et de l'Innovation - Programme de soutien aux organismes de recherche et d’innovation (PSO) - International Volet 2C(Ancien PSR-SIIRI), chercheur principal - 2020-02-03 au 2020-12-31
Détermination du rôle de DCIR dans la pathogenèse associée à l’infection par le VIH-1- MITACS Inc. - Bourse de formation à la recherche MITACS-UL, chercheur principal - 2020-07-10 au 2020-11-09
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Publications
Vesicular MicroRNA as Potential Biomarkers of Viral Rebound, Wilfried Wenceslas Bazié, Julien Boucher, Isidore Tiandiogo Traoré, Dramane Kania, Diane Yirgnur Somé, Michel Alary, Caroline Gilbert, Cells, 2022, 10.3390/cells11050859
Diurnal Variation of Plasma Extracellular Vesicle Is Disrupted in People Living with HIV, Wilfried Wenceslas Bazié, Benjamin Goyer, Julien Boucher, Yuwei Zhang, Delphine Planas, Debashree Chatterjee, Jean-Pierre Routy, Michel Alary, Petronela Ancuta, Caroline Gilbert, Pathogens, 2021, 10.3390/pathogens10050518
Velocity Gradient Separation Reveals a New Extracellular Vesicle Population Enriched in miR-155 and Mitochondrial DNA, Myriam Vaillancourt, Audrey Hubert, Caroline Subra, Julien Boucher, Wilfried Wenceslas Bazié, Julien Vitry, Sofiane Berrazouane, Jean-Pierre Routy, Sylvie Trottier, Cécile Tremblay, Mohammad-Ali Jenabian, Abderrahim Benmoussa, Patrick Provost, Philippe A. Tessier, Caroline Gilbert, Pathogens, 2021, 10.3390/pathogens10050526
Plasma extracellular vesicle subtypes may be useful as potential biomarkers of immune activation in people with HIV, Bazié, W.W., Boucher, J., Vitry, J., Goyer, B., Routy, J.P., Tremblay, C., Trottier, S., Jenabian, M.-A., Provost, P., Alary, M., Gilbert, C., Pathogens and Immunity, 2021, 10.20411/pai.v6i1.384
Endogenous retrovirus-encoded Syncytin-2 contributes to exosome-mediated immunosuppression of T cells, Lokossou, A.G., Toudic, C., Nguyen, P.T., Elisseeff, X., Vargas, A., Rassart, É., Lafond, J., Leduc, L., Bourgault, S., Gilbert, C., Scorza, T., Tolosa, J., Barbeau, B., Biology of Reproduction, 2020, 10.1093/biolre/ioz124
Platelets disseminate extracellular vesicles in lymph in rheumatoid arthritis, Tessandier, N., Melki, I., Cloutier, N., Allaeys, I., Miszta, A., Tan, S., Milasan, A., Michel, S., Benmoussa, A., Lévesque, T., Côté, F., McKenzie, S.E., Gilbert, C., Provost, P., Brisson, A.R., Wolberg, A.S., Fortin, P.R., Martel, C., Boilard, É., Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, 10.1161/ATVBAHA.119.313698
Concentrates of two subsets of extracellular vesicles from cow’s milk modulate symptoms and inflammation in experimental colitis, Benmoussa, A., Diallo, I., Salem, M., Michel, S., Gilbert, C., Sévigny, J., Provost, P., Scientific Reports, 2019, 10.1038/s41598-019-51092-1
Identification of protein markers for extracellular vesicle (EV) subsets in cow's milk, Benmoussa, A., Gotti, C., Bourassa, S., Gilbert, C., Provost, P., Journal of Proteomics, 2019, 10.1016/j.jprot.2018.08.010
Plasma extracellular vesicles as phenotypic biomarkers in prostate cancer patients, Joncas, F.-H., Lucien, F., Rouleau, M., Morin, F., Leong, H.S., Pouliot, F., Fradet, Y., Gilbert, C., Toren, P., Prostate, 2019, 10.1002/pros.23901
Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines, Théry, C., Witwer, K.W., Aikawa, E., Alcaraz, M.J., Anderson, J.D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin-Smith, G.K., Ayre, D.C., Bach, J.-M., Bachurski, D., Baharvand, H., Balaj, L., Baldacchino, S., Bauer, N.N., Baxter, A.A., Bebawy, M., Beckham, C., Bedina Zavec, A., Benmoussa, A., Berardi, A.C., Bergese, P., Bielska, E., Blenkiron, C., Bobis-Wozowicz, S., Boilard, E., Boireau, W., Bongiovanni, A., Borràs, F.E., Bosch, S., Boulanger, C.M., Breakefield, X., Breglio, A.M., Brennan, M.Á., Brigstock, D.R., Brisson, A., Broekman, M.L.D., Bromberg, J.F., Bryl-Górecka, P., Buch, S., Buck, A.H., Burger, D., Busatto, S., Buschmann, D., Bussolati, B., Buzás, E.I., Byrd, J.B., Camussi, G., Carter, D.R.F., Caruso, S., Chamley, L.W., Chang, Y.-T., Chaudhuri, A.D., Chen, C., Chen, S., Cheng, L., Chin, A.R., Clayton, A., Clerici, S.P., Cocks, A., Cocucci, E., Coffey, R.J., Cordeiro-da-Silva, A., Couch, Y., Coumans, F.A.W., Coyle, B., Crescitelli, R., Criado, M.F., D’Souza-Schorey, C., Das, S., de Candia, P., De Santana, E.F., De Wever, O., del Portillo, H.A., Demaret, T., Deville, S., Devitt, A., Dhondt, B., Di Vizio, D., Dieterich, L.C., Dolo, V., Dominguez Rubio, A.P., Dominici, M., Dourado, M.R., Driedonks, T.A.P., Duarte, F.V., Duncan, H.M., Eichenberger, R.M., Ekström, K., EL Andaloussi, S., Elie-Caille, C., Erdbrügger, U., Falcón-Pérez, J.M., Fatima, F., Fish, J.E., Flores-Bellver, M., Försönits, A., Frelet-Barrand, A., Fricke, F., Fuhrmann, G., Gabrielsson, S., Gámez-Valero, A., Gardiner, C., Gärtner, K., Gaudin, R., Gho, Y.S., Giebel, B., Gilbert, C., Gimona, M., Giusti, I., Goberdhan, D.C.I., Görgens, A., Gorski, S.M., Greening, D.W., Gross, J.C., Gualerzi, A., Gupta, G.N., Gustafson, D., Handberg, A., Haraszti, R.A., Harrison, P., Hegyesi, H., Hendrix, A., Hill, A.F., Hochberg, F.H., Hoffmann, K.F., Holder, B., Holthofer, H., Hosseinkhani, B., Hu, G., Huang, Y., Huber, V., Hunt, S., Ibrahim, A.G.-E., Ikezu, T., Inal, J.M., Isin, M., Ivanova, A., Jackson, H.K., Jacobsen, S., Jay, S.M., Jayachandran, M., Jenster, G., Jiang, L., Johnson, S.M., Jones, J.C., Jong, A., Jovanovic-Talisman, T., Jung, S., Kalluri, R., Kano, S.-I., Kaur, S., Kawamura, Y., Keller, E.T., Khamari, D., Khomyakova, E., Khvorova, A., Kierulf, P., Kim, K.P., Kislinger, T., Klingeborn, M., Klinke, D.J., Kornek, M., Kosanović, M.M., Kovács, Á.F., Krämer-Albers, E.-M., Krasemann, S., Krause, M., Kurochkin, I.V., Kusuma, G.D., Kuypers, S., Laitinen, S., Langevin, S.M., Languino, L.R., Lannigan, J., Lässer, C., Laurent, L.C., Lavieu, G., Lázaro-Ibáñez, E., Le Lay, S., Lee, M.-S., Lee, Y.X.F., Lemos, D.S., Lenassi, M., Leszczynska, A., Li, I.T.S., Liao, K., Libregts, S.F., Ligeti, E., Lim, R., Lim, S.K., Linē, A., Linnemannstöns, K., Llorente, A., Lombard, C.A., Lorenowicz, M.J., Lörincz, Á.M., Lötvall, J., Lovett, J., Lowry, M.C., Loyer, X., Lu, Q., Lukomska, B., Lunavat, T.R., Maas, S.L.N., Malhi, H., Marcilla, A., Mariani, J., Mariscal, J., Martens-Uzunova, E.S., Martin-Jaular, L., Martinez, M.C., Martins, V.R., Mathieu, M., Mathivanan, S., Maugeri, M., McGinnis, L.K., McVey, M.J., Meckes, D.G., Meehan, K.L., Mertens, I., Minciacchi, V.R., Möller, A., Møller Jørgensen, M., Morales-Kastresana, A., Morhayim, J., Mullier, F., Muraca, M., Musante, L., Mussack, V., Muth, D.C., Myburgh, K.H., Najrana, T., Nawaz, M., Nazarenko, I., Nejsum, P., Neri, C., Neri, T., Nieuwland, R., Nimrichter, L., Nolan, J.P., Nolte-’t Hoen, E.N.M., Noren Hooten, N., O’Driscoll, L., O’Grady, T., O’Loghlen, A., Ochiya, T., Olivier, M., Ortiz, A., Ortiz, L.A., Osteikoetxea, X., Ostegaard, O., Ostrowski, M., Park, J., Pegtel, D.M., Peinado, H., Perut, F., Pfaffl, M.W., Phinney, D.G., Pieters, B.C.H., Pink, R.C., Pisetsky, D.S., Pogge von Strandmann, E., Polakovicova, I., Poon, I.K.H., Powell, B.H., Prada, I., Pulliam, L., Quesenberry, P., Radeghieri, A., Raffai, R.L., Raimondo, S., Rak, J., Ramirez, M.I., Raposo, G., Rayyan, M.S., Regev-Rudzki, N., Ricklefs, F.L., Robbins, P.D., Roberts, D.D., Rodrigues, S.C., Rohde, E., Rome, S., Rouschop, K.M.A., Rughetti, A., Russell, A.E., Saá, P., Sahoo, S., Salas-Huenuleo, E., Sánchez, C., Saugstad, J.A., Saul, M.J., Schiffelers, R.M., Schneider, R., Schøyen, T.H., Scott, A., Shahaj, E., Sharma, S., Shatnyeva, O., Shekari, F., Shelke, G.V., Shetty, A.K., Shiba, K., Siljander, P.R.-M., Silva, A.M., Skowronek, A., Snyder, O.L., Soares, R.P., Sódar, B.W., Soekmadji, C., Sotillo, J., Stahl, P.D., Stoorvogel, W., Stott, S.L., Strasser, E.F., Swift, S., Tahara, H., Tewari, M., Timms, K., Tiwari, S., Tixeira, R., Tkach, M., Toh, W.S., Tomasini, R., Torrecilhas, A.C., Tosar, J.P., Toxavidis, V., Urbanelli, L., Vader, P., van Balkom, B.W.M., van der Grein, S.G., Van Deun, J., van Herwijnen, M.J.C., Van Keuren-Jensen, K., van Niel, G., van Royen, M.E., van Wijnen, A.J., Vasconcelos, M.H., Vechetti, I.J., Veit, T.D., Vella, L.J., Velot, É., Verweij, F.J., Vestad, B., Viñas, J.L., Visnovitz, T., Vukman, K.V., Wahlgren, J., Watson, D.C., Wauben, M.H.M., Weaver, A., Webber, J.P., Weber, V., Wehman, A.M., Weiss, D.J., Welsh, J.A., Wendt, S., Wheelock, A.M., Wiener, Z., Witte, L., Wolfram, J., Xagorari, A., Xander, P., Xu, J., Yan, X., Yáñez-Mó, M., Yin, H., Yuana, Y., Zappulli, V., Zarubova, J., Žėkas, V., Zhang, J.-Y., Zhao, Z., Zheng, L., Zheutlin, A.R., Zickler, A.M., Zimmermann, P., Zivkovic, A.M., Zocco, D., Zuba-Surma, E.K., Journal of Extracellular Vesicles, 2018, 10.1080/20013078.2018.1535750
A subset of extracellular vesicles carries the bulk of microRNAs in commercial dairy cow’s milk, Benmoussa, A., Ly, S., Shan, S.T., Laugier, J., Boilard, E., Gilbert, C., Provost, P., Journal of Extracellular Vesicles, 2017, 10.1080/20013078.2017.1401897
Commercial dairy cow milk micrornas resist digestion under simulated gastrointestinal tract conditions, Benmoussa, A., Lee, C.C., Laffont, B., Savard, P., Laugier, J., Boilard, E., Gilbert, C., Fliss, I., Provost, P., Journal of Nutrition, 2016, 10.3945/jn.116.237651
Plasmacytoid dendritic cells and myeloid cells differently contribute to B-cell-activating factor belonging to the tumor necrosis factor superfamily overexpression during primary HIV infection, Borhis, G., Burelout, C., Chaoul, N., Smith, N., Goujard, C., Meyer, L., Paul, S., Saoudin, H., Hosmalin, A., Gilbert, C., Herbeuval, J.-P., Richard, Y., AIDS, 2016, 10.1097/QAD.0000000000000965
Elevated abundance, size, and MicroRNA content of plasma extracellular vesicles in viremic HIV-1+ patients: Correlations with known markers of disease progression, Hubert, A., Subra, C., Jenabian, M.-A., Labrecque, P.-F.T., Tremblay, C., Laffont, B., Provost, P., Routy, J.-P., Gilbert, C., Journal of Acquired Immune Deficiency Syndromes, 2015, 10.1097/QAI.0000000000000756
Exosome release following activation of the dendritic cell immunoreceptor: A potential role in HIV-1 pathogenesis, Mfunyi, C.M., Vaillancourt, M., Vitry, J., Nsimba Batomene, T.-R., Posvandzic, A., Lambert, A.A., Gilbert, C., Virology, 2015, 10.1016/j.virol.2015.05.013
Role and future applications of extracellular vesicles in HIV-1 pathogenesis, Hubert, A., Barbeau, B., Subra, C., Bissonnette, L., Gilbert, C., Future Virology, 2015, 10.2217/fvl.15.11
Secretion of S100A8, S100A9, and S100A12 by Neutrophils Involves Reactive Oxygen Species and Potassium Efflux, Tardif, M.R., Chapeton-Montes, J.A., Posvandzic, A., Pagé, N., Gilbert, C., Tessier, P.A., Journal of Immunology Research, 2015, 10.1155/2015/296149
Syncytin proteins incorporated in placenta exosomes are important for cell uptake and show variation in abundance in serum exosomes from patients with preeclampsia, Vargas, A., Zhou, S., Et́hier-Chiasson, M., Flipo, D., Lafond, J., Gilbert, C., Barbeau, B., FASEB Journal, 2014, 10.1096/fj.13-239053
Dendritic Cell Immunoreceptor Is a New Target for Anti-AIDS Drug Development: Identification of DCIR/HIV-1 Inhibitors, Lambert, A.A., Azzi, A., Lin, S.-X., Allaire, G., St-Gelais, K.P., Tremblay, M.J., Gilbert, C., PLoS ONE, 2013, 10.1371/journal.pone.0067873
Exosomes derived from HIV-1-infected cells contain trans-activation response element RNA, Narayanan, A., Iordanskiy, S., Das, R., Van Duyne, R., Santos, S., Jaworski, E., Guendel, I., Sampey, G., Dalby, E., Iglesias-Ussel, M., Popratiloff, A., Hakami, R., Kehn-Hall, K., Young, M., Subra, C., Gilbert, C., Bailey, C., Romerio, F., Kashanchi, F., Journal of Biological Chemistry, 2013, 10.1074/jbc.M112.438895
DCIR-mediated enhancement of HIV-1 infection requires the ITIM-associated signal transduction pathway, Lambert, A.A., Barabé, F., Gilbert, C., Tremblay, M.J., Blood, 2011, 10.1182/blood-2011-01-331363
HIV-1 induces DCIR expression in CD4+ T cells, Lambert, A.A., Imbeault, M.L., Gilbert, C., Tremblay, M.J., PLoS Pathogens, 2010, 10.1371/journal.ppat.1001188
Efficient replication of human immunodeficiency virus type 1 in resting CD4+ T lymphocytes is induced by coculture with autologous dendritic cells in the absence of foreign antigens, Barat, C., Gilbert, C., Tremblay, M.J., Journal of Virology, 2009, 10.1128/JVI.01420-08
LFA-1 antagonists as agents limiting human immunodeficiency virus type 1 infection and transmission and potentiating the effect of the fusion inhibitor T-20, Tardif, M.R., Gilbert, C., Thibault, S., Fortin, J.-F., Tremblay, M.J., Antimicrobial Agents and Chemotherapy, 2009, 10.1128/AAC.00117-09
Discrimination between exosomes and HIV-1: Purification of both vesicles from cell-free supernatants, Cantin, R., Diou, J., Bélanger, D., Tremblay, A.M., Gilbert, C., Journal of Immunological Methods, 2008, 10.1016/j.jim.2008.07.007
Extracellular ATP reduces HIV-1 transfer from immature dendritic cells to CD4+ T lymphocytes, Barat, C., Gilbert, C., Imbeault, M., Tremblay, M.J., Retrovirology, 2008, 10.1186/1742-4690-5-30
LPS reduces HIV-1 replication in primary human macrophages partly through an endogenous production of type I interferons, Simard, S., Maurais, É., Gilbert, C., Tremblay, M.J., Clinical Immunology, 2008, 10.1016/j.clim.2008.01.007
Nucleobindin co-localizes and associates with cyclooxygenase (COX)-2 in human neutrophils, Leclerc, P., Biarc, J., St.-Onge, M., Gilbert, C., Dussault, A.-A., Laflamme, C., Pouliot, M., PLoS ONE, 2008, 10.1371/journal.pone.0002229
The C-type lectin surface receptor DCIR acts as a new attachment factor for HIV-1 in dendritic cells and contributes to trans- and cis-infection pathways, Lambert, A.A., Gilbert, C., Richard, M., Beaulieu, A.D., Tremblay, M.J., Blood, 2008, 10.1182/blood-2008-01-136473
Crystal-induced neutrophil activation. IX. Syk-dependent activation of class Ia phosphatidylinositol 3-kinase, Popa-Nita, O., Rollet-Labelle, E., Thibault, N., Gilbert, C., Bourgoin, S.G., Naccache, P.H., Journal of Leukocyte Biology, 2007, 10.1189/jlb.0307174
Human immunodeficiency virus type 1 replication in dendritic cell-T-cell cocultures is increased upon incorporation of host LFA-1 due to higher levels of virus production in immature dendritic cells, Gilbert, C., Cantin, R., Barat, C., Tremblay, M.J., Journal of Virology, 2007, 10.1128/JVI.02810-06
Human immunodeficiency virus type 1-associated CD40 ligand transactivates B lymphocytes and promotes infection of CD4+ T cells, Martin, G., Roy, J., Barat, C., Ouellet, M., Gilbert, C., Tremblay, M.J., Journal of Virology, 2007, 10.1128/JVI.02542-06
Involvement of Src and Syk tyrosine kinases in HIV-1 transfer from dendritic cells to CD4+ T lymphocytes, Gilbert, C., Barat, C., Cantin, R., Tremblay, M.J., Journal of Immunology, 2007, 10.4049/jimmunol.178.5.2862
Virus-associated host CD62L increases attachment of human immunodeficiency virus type 1 to endothelial cells and enhances trans infection of CD4+ T lymphocytes, Thibault, S., Tardif, M.R., Gilbert, C., Tremblay, M.J., Journal of General Virology, 2007, 10.1099/vir.0.83032-0
Characterization of an activation factor released from human neutrophils after stimulation by triclinic monosodium urate crystals, Desaulniers, P., Marois, S., Paré, G., Popa-Nita, O., Gilbert, C., Naccache, P.H., Journal of Rheumatology, 2006
Statins could be used to control replication of some viruses, including HIV-1, Gilbert, C., Bergeron, M., Méthot, S., Giguère, J.-F., Tremblay, M.J., Viral Immunology, 2005, 10.1089/vim.2005.18.474
Monosodium urate monohydrate crystals induce the release of the proinflammatory protein S100A8/A9 from neutrophils, Ryckman, C., Gilbert, C., De Médicis, R., Lussier, A., Vandal, K., Tessier, P.A., Journal of Leukocyte Biology, 2004, 10.1189/jlb.0603294
The importance of virus-associated host ICAM-1 in human immunodeficiency virus type 1 dissemination depends on the cellular context, Bounou, S., Giguère, J.-F., Cantin, R., Gilbert, C., Imbeault, M., Martin, G., Tremblay, M.J., FASEB Journal, 2004, 10.1096/fj.04-1755fje
Chemotactic factor-induced recruitment and activation of Tec family kinases in human neutrophils. II. Effects of LFM-A13, a specific Btk inhibitor, Gilbert, C., Levasseur, S., Desaulniers, P., Dusseault, A.-A., Thibault, N., Bourgoin, S.G., Naccache, P.H., Journal of Immunology, 2003, 10.4049/jimmunol.170.10.5235
Crystal-induced neutrophil activation: VIII. Immediate production of prostaglandin E2 mediated by constitutive cyclooxygenase 2 in human neutrophils stimulated by urate crystals, Gilbert, C., Poubelle, P.E., Borgeat, P., Pouliot, M., Naccache, P.H., Arthritis and Rheumatism, 2003, 10.1002/art.10851
Human neutrophils as a source of nociceptin: A novel link between pain and inflammation, Fiset, M.-É., Gilbert, C., Poubelle, P.E., Pouliot, M., Biochemistry, 2003, 10.1021/bi0300635
Early events in the activation of FcγRIIA in human neutrophils: Stimulated insolubilization, translocation to detergent-resistant domains, and degradation of FcγRIIA, Barabé, F., Rollet-Labelle, E., Gilbert, C., Fernandes, M.J.G., Naccache, S.N., Naccache, P.H., Journal of Immunology, 2002, 10.4049/jimmunol.168.8.4042
Immunoblotting and sequential lysis protocols for the analysis of tyrosine phosphorylation-dependent signaling, Gilbert, C., Rollet-Labelle, E., Caon, A.C., Naccache, P.H., Journal of Immunological Methods, 2002, 10.1016/S0022-1759(02)00347-2
Preservation of the pattern of tyrosine phosphorylation in human neutrophil lysates: II. A sequential lysis protocol for the analysis of tyrosine phosphorylation-dependent signalling, Gilbert, C., Rollet-Labelle, E., Naccache, P.H., Journal of Immunological Methods, 2002, 10.1016/S0022-1759(01)00553-1
Crystal-induced neutrophil activation. VII. Involvement of Syk in the responses to monosodium urate crystals, Desaulniers, P., Fernandes, M., Gilbert, C., Bourgoin, S.G., Naccache, P.H., Journal of Leukocyte Biology, 2001
Evidence for a role for SAM68 in the responses of human neutrophils to ligation of CD32 and to monosodium urate crystals, Gilbert, C., Barabé, F., Rollet-Labelle, E., Bourgoin, S.G., McColl, S.R., Damaj, B.B., Naccache, P.H., Journal of Immunology, 2001, 10.4049/jimmunol.166.7.4664
Adenosine, a potent natural suppressor of arachidonic acid release and leukotriene biosynthesis in human neutrophils, Flamand, N., Boudreault, S., Picard, S., Austin, M., Surette, M.E., Plante, H., Krump, E., Vallée, M.-J., Gilbert, C., Naccache, P., Laviolette, M., Borgeat, P., American Journal of Respiratory and Critical Care Medicine, 2000, 10.1164/ajrccm.161.supplement_1.ltta-18
Modulation of human neutrophil responses to CD32 cross-linking by serine/threonine phosphatase inhibitors: Cross-talk between serine/threonine and tyrosine phosphorylation, Rollet-Labelle, E., Gilbert, C., Naccache, P.H., Journal of Immunology, 2000, 10.4049/jimmunol.164.2.1020
TNF-induced haptoglobin release from human neutrophils: Pivotal role of the TNF p55 receptor, Berkova, N., Gilbert, C., Goupil, S., Yan, J., Korobko, V., Naccache, P.H., Journal of Immunology, 1999
Crystal-induced neutrophil activation VI. Involvement of FcγRIIIB (CD16) and CD11b in response to inflammatory microcrystals, Barabé, F., Gilbert, C., Liao, N., Bourgoin, S.G., Naccache, P.H., FASEB Journal, 1998, 10.1096/fasebj.12.2.209
Expression and activity of prostaglandin endoperoxide synthase-2 in agonist-activated human neutrophils, Pouliot, M., Gilbert, C., Borgeat, P., Poubelle, P.E., Bourgoin, S., Créminon, C., Maclouf, J., McColl, S.R., Naccache, P.H., FASEB Journal, 1998, 10.1096/fasebj.12.12.1109
Agonist-specific tyrosine phosphorylation of Cbl in human neutrophils, Naccache, P.H., Gilbert, C., Barabé, F., Al-Shami, A., Mahana, W., Bourgoin, S.G., Journal of Leukocyte Biology, 1997, 10.1002/jlb.62.6.901
Preservation of the pattern of tyrosine phosphorylation in human neutrophil lysates, Al-Shami, A., Gilbert, C., Barabé, F., Gaudry, M., Naccache, P.H., Journal of Immunological Methods, 1997, 10.1016/S0022-1759(97)00004-5
Paradoxical effects of colchicine on the activation of human neutrophils by chemotactic factors and inflammatory microcrystals, Roberge, C.J., Gaudry, M., Gilbert, C., Malawista, S.E., De Médicis, R., Lussier, A., Poubelle, P.E., Naccache, P.H., Journal of Leukocyte Biology, 1996, 10.1002/jlb.59.6.864
Activation of Lyn is a common element of the stimulation of human neutrophils by soluble and particulate agonists, Gaudry, M., Gilbert, C., Barabé, F., Poubelle, P.E., Naccache, P.H., Blood, 1995, 10.1182/blood.v86.9.3567.bloodjournal8693567
Inhibition of tyrosine phosphorylation by Wortmannin in human neutrophils. Dissociation from its inhibitory effects on phospholipase D, Naccache, P.H., Caon, A.C., Gilbert, C., Gaudry, M., Roberge, C.J., Poubelle, P.E., Bourgoin, S., Laboratory Investigation, 1993
Evidence for the involvement of tyrosine kinases in the locomotory responses of human neutrophils, Gaudry, M., Caon, A.C., Gilbert, C., Lille, S., Naccache, P.H., Journal of Leukocyte Biology, 1992, 10.1002/jlb.51.2.103
Rapid priming of calcium mobilization and superoxide anion production in human neutrophils by substimulatory concentrations of phorbol esters: A novel role for protein kinase C and tyrosine phosphorylation in the up-modulation of signal transduction, Gilbert, C., Gaudry, M., Naccache, P.H., Cellular Signalling, 1992, 10.1016/0898-6568(92)90020-9
Crystal‐induced neutrophil activation. I. Initiation and modulation of calcium mobilization and superoxide production by microcrystals, Naccache, P.H., Grimard, M., Roberge, C.J., Gilbert, C., Poubelle, P.E., Lussier, A., De Médicis, R., Arthritis & Rheumatism, 1991, 10.1002/art.1780340311
Pertussis toxin selectively interferes with the responses of the HL-60 human promyelocytic cell line to dimethylsulfoxide, Naccache, P.H., Caon, A.C., Gilbert, C., Chouinard, G., McColl, S.R., Blood, 1991, 10.1182/blood.v78.10.2534.2534
Priming of the human neutrophil respiratory burst by granulocyte-macrophage colony-stimulating factor and tumor necrosis factor-α involves regulation at a post-cell surface receptor level: Enhancement of the effect of agents which directly activate G proteins, McColl, S.R., Beauseigle, D., Gilbert, C., Naccache, P.H., Journal of Immunology, 1990
Selective inhibition of human neutrophil functional responsiveness by Erbstatin, an inhibitor of tyrosine protein kinase, Naccache, P.H., Gilbert, C., Caon, A.C., Gaudry, M., Huang, C.-K., Bonak, V.A., Umezawa, K., McColl, S.R., Blood, 1990, 10.1182/blood.v76.10.2098.2098
Chemoattractant-induced cytoplasmic pH changes and cytoskeletal reorganization in human neutrophils. Relationship to the stimulated calcium transients and oxidative burst, Naccache, P.H., Therrien, S., Caon, A.C., Liao, N., Gilbert, C., McColl, S.R., Journal of Immunology, 1989
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Contribution à l'enseignement aux cycles supérieurs
Étudiant(e)s dirigé(e)s*
Depuis 2009
Éric Malenfant - Maitrîse avec mémoire - En cours
Sophie Proulx - Doctorat - En cours
Emma Bourgeault - Maitrîse avec mémoire - En cours
Wilfried Wenceslas Bazie - Doctorat - En cours
Julien Boucher - Doctorat - En cours
Arnaud Driussi - Doctorat - En cours
Gabriel Pépin - Maitrîse avec mémoire - En cours
Jean Dory Francois - Maitrîse avec mémoire - En cours
Alyssa Rousseau - Maitrîse avec mémoire - En cours
Richard Chebbabi - Doctorat - En cours
Gabrielle Beaulieu-Carbonneau - Maitrîse avec mémoire - En cours
Aliona Bancila - Maitrîse avec mémoire - 2011/01
Claude Mukeba Mfunyi - Maitrîse avec mémoire - 2013/01
Julie Andrea Chapeton Montes - Maitrîse avec mémoire - 2015/05
Thy-Rene Nsimba Batomene - Maitrîse avec mémoire - 2016/01
Sofiane Berrazouane - Maitrîse avec mémoire - 2016/01
Audrey Hubert - Doctorat - 2016/09
Julien Pierre Vitry - Maitrîse avec mémoire - 2017/01
Myriam Tremblay - Maitrîse avec mémoire - 2019/09
Yanis Chaib - Maitrîse avec mémoire - 2020/01
Encadrement d'étudiant(e)s pour les programmes suivants :
*Les supervisions d’étudiant(e)s de 1er cycle en
stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées
ultérieurement.
Vice-décanat à la recherche et aux études supérieures Pavillon Ferdinand-Vandry Université Laval 1050, avenue de la Médecine, local 4645 Québec (Québec) G1V 0A6 Canada
Catherine Comtois Agente de gestion des études etudes.sup2@fmed.ulaval.ca Biostatistique Épidémiologie Évaluation économique des technologies de la santé Santé publique
Marianne Rivest et Claudia Gonzalez Agentes de gestion des études etudes.sup1@fmed.ulaval.ca Biologie cellulaire et moléculaire Génomique fonctionnelle Médecine moléculaire Microbiologie-immunologie Neurosciences
Isabelle Tremblay Agente de gestion des études etudes.sup3@fmed.ulaval.ca Pédagogie universitaire en sciences de la santé Sciences cliniques et biomédicales Sciences de la réadaptation Prévention et gestion de la santé et de la sécurité au travail