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Vincenzo Di Marzo

Professeur titulaire

Groupe interdisciplinaire de recherche sur l'obésité de l'Université Laval
Centre thématique de recherche en neurosciences
Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec
Nutrition, santé et société (NUTRISS)
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Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Bioinformatique / données massives (big data)
Neurosciences et santé mentale
Reproduction, génétique, périnatalité et développement
Santé cardiovasculaire, respiratoire et métabolisme

Domaines et intérêts de recherche du (de la) professeur(e) :

Neurosciences, santé mentale et toxicomanies
  • Récepteurs et transporteurs
  • Signalisation cellulaire
  • Troubles de l'alimentation
  • Activité nerveuse et synaptique
Nutrition et métabolisme
  • Appétit
  • Diabète
  • Maladies lipidiques
  • Obésité
  • Nutrition
  • Produits nutraceutiques et aliments fonctionnels
  • Métabolisme énergétique
  • Désordres métaboliques
  • Appareil digestif
Santé circulatoire et respiratoire
  • Maladies cardiovasculaires
  • Athérosclérose

Projets de recherche

  • Fonds institutionnel d'exploitation des infrastructures pour l'Université Laval - Fondation Canadienne pour l'innovation (La) - Fonds d'exploitation des infrastructures (FEI), co-chercheur - 2002-04-01 au 2025-03-31
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.1 - Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.3 - Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.2 - Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 3.2 - Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
  • FMéd --- Canada Excellence Research Chair on the microbiome-endocannabinoidome connection in metabolic health - Instituts de recherche en santé du Canada, Université Laval - Fonds internes - Programme de chaires d'excellence en recherche du Canada, chercheur principal - 2017-06-01 au 2024-05-31
  • FSAA --- Canada Excellence Research Chair on the microbiome-endocannabinoidome connection in metabolic health - Université Laval - Fonds internes, Instituts de recherche en santé du Canada - Programme de chaires d'excellence en recherche du Canada, chercheur principal - 2017-06-01 au 2024-05-31
  • Canada Excellence Research Chair on the microbiome-endocannabinoidome connection in metabolic health - Instituts de recherche en santé du Canada - Programme de chaires d'excellence en recherche du Canada, chercheur principal - 2017-06-01 au 2024-05-31
  • Institut sur la nutrition et les aliments fonctionnels (INAF) - Institut national de recherche scientifique (INRS), Fonds de recherche du Québec - Nature et technologies, Université Laval - Fonds internes, Université McGill, Université du Québec à Rimouski, Université de Sherbrooke - Regroupements stratégiques NT, co-chercheur - 2017-04-01 au 2024-03-31
  • Nutrition and brain health, from predictive biology to disease prevention and treatment - Food4BrainHealth - Université Laval - Fonds internes, Université McGill, Université de Toronto, Institut national de la recherche agronomique - Réseau de recherche international (RRI), co-chercheur - 2019-03-18 au 2024-03-17
  • FMÉD --- Support de Sentinelle Nord à l'Unité mixte internationale sur la recherche chimique et biomoléculaire de microbiome - Secrétariat des programmes interorganismes à l’intention des établissements - Fonds d'excellence en recherche Apogée Canada, chercheur principal - 2017-06-01 au 2023-08-31
  • The role of full-fat dairy products on body weigth control and metabolic health in adults - Les producteurs laitiers du Canada - Dairy Research Cluster 3, co-chercheur - 2018-09-01 au 2023-03-31
  • FSAA --- Support de Sentinelle Nord à l'Unité mixte internationale sur la recherche chimique et biomoléculaire de microbiome - Secrétariat des programmes interorganismes à l’intention des établissements - Fonds d'excellence en recherche Apogée Canada, chercheur principal - 2016-11-29 au 2022-08-31
  • Programme de soutien aux nouveaux chercheurs - Université Laval - Fonds internes - Soutien facultaire aux jeunes chercheurs de la Faculté de médecine, chercheur principal - 2019-07-01 au 2022-06-30
  • Microbiome-In-GutVitro: étude préliminaire de séquençage multi-règnes pour le développement d’une approche analytique dans l’identification de microorganismes non-bactériens membres du microbiome intestinal en système M-SHIME - Fonds de recherche du Québec - Santé - Projet subsidiaire - Nouveaux Centres et Instituts de recherche - Subventions régulières (pour fins de gestion au VRRCI), co-chercheur - 2021-06-09 au 2022-06-08
  • Étude de l'impact de la transplantation fécal sur l'amélioration du diabète après la chirurgie bariatrique - Fonds de recherche du Québec - Santé - Réseaux thématiques de recherche, chercheur principal - 2021-02-15 au 2022-03-31
  • Aménagement d'espaces de recherche dédiés à de la recherche de pointe sur le microbiome - Université Laval - Fonds internes, Ministère de l'Économie et de l'Innovation - Programme de soutien aux organismes de recherche et d'innovation (PSO) - Volet 4: Soutien au financement d'infrastructures de recherche et d'innovation, chercheur principal - 2019-04-01 au 2021-11-30
  • Territorialiser les systèmes alimentaires : une révolution pour la planète et la santé durable - Alliance santé Québec (AsQ), co-chercheur - 2020-04-01 au 2021-03-31
  • Role of the gut microbiome-endocannabinoidome axis in metabolic health and its therapeutic exploitation - phase 2 - Fondation Canadienne pour l'innovation (La), Ministère de l'éducation et de l'enseignement supérieur - Fonds des leaders John-R.-Evans (FLJR), chercheur principal - 2018-09-01 au 2021-03-31
  • Study of the role of the gut microbiome-endocannabinoidome axis in metabolic health and its therapeutic exploitation - Ministère de la Santé et des Services sociaux, Ministère de l'éducation et de l'enseignement supérieur, Fondation Canadienne pour l'innovation (La) - Fonds des leaders John-R.-Evans (FLJR), chercheur principal - 2018-04-01 au 2021-03-31
  • Deciphering and tackling the complex etiology of chronic societal diseases (CSDs) - Fondation Canadienne pour l'innovation (La), Institut universitaire de cardiologie et de pneumologie de Québec, Ministère de la Santé et des Services sociaux, Université Laval - Fonds internes, Ministère de l'éducation et de l'enseignement supérieur - Fonds d'innovation (FI), co-chercheur - 2018-02-01 au 2020-03-31
  • FEI du projet : Study of the role of the gut microbiome-endocannabinoidome axis in metabolic health and its therapeutic exploitation - Fondation Canadienne pour l'innovation (La), chercheur principal - 2019-04-01 au 2020-03-31
  • 3.8 Deciphering host-microbial interactions for cardiometabolic and mental health disorders with novel multimodal light-based sensing tools - Secrétariat des programmes interorganismes à l’intention des établissements - Fonds d'excellence en recherche Apogée Canada, co-chercheur - 2016-04-01 au 2020-03-31
  • Dissecting host-microbiome modifiers of type 2 diabetes risk and complications - Avis d'intention - Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-03-01 au 2020-02-29

Publications

  • Cannabinoids: a class of unique natural products with unique pharmacology, Fabiana Piscitelli, Vincenzo Di Marzo, Rendiconti Lincei. Scienze Fisiche e Naturali, 2021, 10.1007/s12210-020-00966-y
  • A Glucuronic Acid-Palmitoylethanolamide Conjugate (GLUPEA) Is an Innovative Drug Delivery System and a Potential Bioregulator, Emiliano Manzo, Aniello Schiano Moriello, Francesco Tinto, Roberta Verde, Marco Allarà, Luciano De Petrocellis, Ester Pagano, Angelo A. Izzo, Vincenzo Di Marzo, Stefania Petrosino, Cells, 2021, 10.3390/cells10020450
  • Linking the Endocannabinoidome with Specific Metabolic Parameters in an Overweight and Insulin-Resistant Population: From Multivariate Exploratory Analysis to Univariate Analysis and Construction of Predictive Models, Clara Depommier, Nicolas Flamand, Rudy Pelicaen, Dominique Maiter, Jean-Paul Thissen, Audrey Loumaye, Michel P. Hermans, Amandine Everard, Nathalie M. Delzenne, Vincenzo Di Marzo, Patrice D. Cani, Cells, 2021, 10.3390/cells10010071
  • Mgll Knockout Mouse Resistance to Diet-Induced Dysmetabolism Is Associated with Altered Gut Microbiota, Niokhor Dione, Sébastien Lacroix, Ulrike Taschler, Thomas Deschênes, Armita Abolghasemi, Nadine Leblanc, Vincenzo Di Marzo, Cristoforo Silvestri, Cells, 2020, 10.3390/cells9122705
  • Role of 2-Arachidonoyl-Glycerol and CB1 Receptors in Orexin-A-Mediated Prevention of Oxygen–Glucose Deprivation-Induced Neuronal Injury, Letizia Palomba, Andrea Motta, Roberta Imperatore, Fabiana Piscitelli, Raffaele Capasso, Federica Mastroiacovo, Giuseppe Battaglia, Valeria Bruno, Luigia Cristino, Vincenzo Di Marzo, Cells, 2020, 10.3390/cells9061507
  • Hepatic NAPE-PLD Is a Key Regulator of Liver Lipid Metabolism, Charlotte Lefort, Martin Roumain, Matthias Van Hul, Marialetizia Rastelli, Rita Manco, Isabelle Leclercq, Nathalie M. Delzenne, Vincenzo Di Marzo, Nicolas Flamand, Serge Luquet, Cristoforo Silvestri, Giulio G. Muccioli, Patrice D. Cani, Cells, 2020, 10.3390/cells9051247
  • Obesity Affects the Microbiota–Gut–Brain Axis and the Regulation Thereof by Endocannabinoids and Related Mediators, Nicola Forte, Alba Clara Fernández-Rilo, Letizia Palomba, Vincenzo Di Marzo, Luigia Cristino, International Journal of Molecular Sciences, 2020, 10.3390/ijms21051554
  • Cannabinoids and the expanded endocannabinoid system in neurological disorders, Luigia Cristino, Tiziana Bisogno, Vincenzo Di Marzo, Nature Reviews Neurology, 2020, 10.1038/s41582-019-0284-z
  • Cannabidiol improves vocal learning-dependent recovery from, and reduces magnitude of deficits following, damage to a cortical-like brain region in a songbird pre-clinical animal model, Ali Alalawi, Julien C. Dodu, Marie Woolley-Roberts, James Brodie, Vincenzo Di Marzo, Ken Soderstrom, Neuropharmacology, 2019, 10.1016/j.neuropharm.2019.107716
  • Corrigendum to “Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system” [Biochem. Pharmacol. 161 (2019) 37–51], Maciej Salaga, Agata Binienda, Fabiana Piscitelli, Anna Mokrowiecka, Adam I. Cygankiewicz, Roberta Verde, Ewa Malecka-Panas, Radzislaw Kordek, Wanda M. Krajewska, Vincenzo Di Marzo, Jakub Fichna, Biochemical Pharmacology, 2019, 10.1016/j.bcp.2019.113636
  • Effects of Dietary Bisphenol A on the Reproductive Function of Gilthead Sea Bream (Sparus aurata) Testes, Isabel Forner-Piquer, Ioannis Fakriadis, Constantinos C Mylonas, Fabiana Piscitelli, Vincenzo Di Marzo, Francesca Maradonna, Josep Calduch-Giner, Jaume Pérez-Sánchez, Oliana Carnevali, International Journal of Molecular Sciences, 2019, 10.3390/ijms20205003
  • Structure-activity relationships of thiazole and benzothiazole derivatives as selective cannabinoid CB2 agonists with in vivo anti-inflammatory properties, Aya E. Ghonim, Alessia Ligresti, Alessandro Rabbito, Ali Mokhtar Mahmoud, Vincenzo Di Marzo, Noha A. Osman, Ashraf H. Abadi, European Journal of Medicinal Chemistry, 2019, 10.1016/j.ejmech.2019.07.002
  • Cannabinoid receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database, Mary Abood, Stephen P.H. Alexander, Francis Barth, Tom I. Bonner, Heather Bradshaw, Guy Cabral, Pierre Casellas, Ben F. Cravatt, William A. Devane, Vincenzo Di Marzo, Maurice R. Elphick, Christian C. Felder, Peter Greasley, Miles Herkenham, Allyn C. Howlett, George Kunos, Ken Mackie, Raphael Mechoulam, Roger G. Pertwee, Ruth A. Ross, IUPHAR/BPS Guide to Pharmacology CITE, 2019, 10.2218/gtopdb/F13/2019.4
  • Discovery of novel benzofuran-based compounds with neuroprotective and immunomodulatory properties for Alzheimer's disease treatment, Serena Montanari, Ali Mokhtar Mahmoud, Letizia Pruccoli, Alessandro Rabbito, Marina Naldi, Sabrina Petralla, Ignacio Moraleda, Manuela Bartolini, Barbara Monti, Isabel Iriepa, Federica Belluti, Silvia Gobbi, Vincenzo Di Marzo, Alessandra Bisi, Andrea Tarozzi, Alessia Ligresti, Angela Rampa, European Journal of Medicinal Chemistry, 2019, 10.1016/j.ejmech.2019.05.080
  • Human leukocytes differentially express endocannabinoid‐glycerol lipases and hydrolyze 2‐arachidonoyl‐glycerol and its metabolites from the 15‐lipoxygenase and cyclooxygenase pathways, Caroline Turcotte, Élizabeth Dumais, Anne‐Sophie Archambault, Cyril Martin, Marie‐Renée Blanchet, Élyse Bissonnette, Louis‐Philippe Boulet, Michel Laviolette, Vincenzo Di Marzo, Nicolas Flamand, Journal of Leukocyte Biology, 2019, 10.1002/jlb.3a0919-049rrr
  • The non-euphoric phytocannabinoid cannabidivarin counteracts intestinal inflammation in mice and cytokine expression in biopsies from UC pediatric patients, E. Pagano, B. Romano, F.A. Iannotti, O.A. Parisi, M. D’Armiento, S. Pignatiello, L. Coretti, M. Lucafò, T. Venneri, G. Stocco, F. Lembo, P. Orlando, R. Capasso, V. Di Marzo, A.A. Izzo, F. Borrelli, Pharmacological Research, 2019, 10.1016/j.phrs.2019.104464
  • Lifestyle and Metabolic Syndrome: Contribution of the Endocannabinoidome, Vincenzo Di Marzo, Cristoforo Silvestri, Nutrients, 2019, 10.3390/nu11081956
  • Altered Metabolism of Phospholipases, Diacylglycerols, Endocannabinoids, and N-Acylethanolamines in Patients with Mastocytosis, Anne Lise Ferrara, Fabiana Piscitelli, Angelica Petraroli, Roberta Parente, Maria Rosaria Galdiero, Gilda Varricchi, Giancarlo Marone, Massimo Triggiani, Vincenzo Di Marzo, Stefania Loffredo, Journal of Immunology Research, 2019, 10.1155/2019/5836476
  • Targeted Lipidomics Investigation of N ‐acylethanolamines in a Transgenic Mouse Model of AD: A Longitudinal Study, Fabiana Piscitelli, Roberto Coccurello, Antonio Totaro, Alessandro Leuti, Giacomo Giacovazzo, Roberta Verde, Emanuela Rossi, Michele Podaliri Vulpiani, Nicola Ferri, Roberto Giacominelli Stuffler, Vincenzo Di Marzo, Sergio Oddi, Tiziana Bisogno, Mauro Maccarrone, European Journal of Lipid Science and Technology, 2019, 10.1002/ejlt.201900015
  • Cannabidivarin completely rescues cognitive deficits and delays neurological and motor defects in male Mecp2 mutant mice, Erica Zamberletti, Marina Gabaglio, Fabiana Piscitelli, James S Brodie, Marie Woolley-Roberts, Isabella Barbiero, Marco Tramarin, Giorgio Binelli, Nicoletta Landsberger, Charlotte Kilstrup-Nielsen, Tiziana Rubino, Vincenzo Di Marzo, Daniela Parolaro, Journal of Psychopharmacology, 2019, 10.1177/0269881119844184
  • Orexin-A Prevents Lipopolysaccharide-Induced Neuroinflammation at the Level of the Intestinal Barrier, Lea Tunisi, Nicola Forte, Alba Clara Fernández-Rilo, Isabella Mavaro, Raffaele Capasso, Livia D'Angelo, Nataša Milić, Luigia Cristino, Vincenzo Di Marzo, Letizia Palomba, Frontiers in Endocrinology, 2019, 10.3389/fendo.2019.00219
  • Altered gut microbiota and endocannabinoid system tone in vitamin D deficiency-mediated chronic pain, Francesca Guida, Serena Boccella, Carmela Belardo, Monica Iannotta, Fabiana Piscitelli, Francesca De Filippis, Salvatore Paino, Flavia Ricciardi, Dario Siniscalco, Ida Marabese, Livio Luongo, Danilo Ercolini, Vincenzo Di Marzo, Sabatino Maione, Brain, Behavior, and Immunity, 2019, 10.1016/j.bbi.2019.04.006
  • N-Oleoyl-glycine reduces nicotine reward and withdrawal in mice, Giulia Donvito, Fabiana Piscitelli, Pretal Muldoon, Asti Jackson, Rosa Maria Vitale, Enrico D'Aniello, Catia Giordano, Bogna M. Ignatowska-Jankowska, Mohammed A. Mustafa, Francesca Guida, Gavin N. Petrie, Linda Parker, Reem Smoum, Laura Sim-Selley, Sabatino Maione, Aron H. Lichtman, M. Imad Damaj, Vincenzo Di Marzo, Raphael Mechoulam, Neuropharmacology, 2019, 10.1016/j.neuropharm.2018.03.020
  • Oleoyl glycine: interference with the aversive effects of acute naloxone-precipitated MWD, but not morphine reward, in male Sprague–Dawley rats, Gavin N. Petrie, Kiri L. Wills, Fabiana Piscitelli, Reem Smoum, Cheryl L. Limebeer, Erin M. Rock, Ashlyn E. Humphrey, Madeleine Sheppard-Perkins, Aron H. Lichtman, Raphael Mechoulam, Vincenzo Di Marzo, Linda A. Parker, Psychopharmacology, 2019, 10.1007/s00213-019-05237-9
  • Identification and characterization of phytocannabinoids as novel dual PPARα/γ agonists by a computational and in vitro experimental approach, Enrico D'Aniello, Tariq Fellous, Fabio Arturo Iannotti, Alessandra Gentile, Marco Allarà, Francesca Balestrieri, Roy Gray, Pietro Amodeo, Rosa Maria Vitale, Vincenzo Di Marzo, Biochimica et Biophysica Acta (BBA) - General Subjects, 2019, 10.1016/j.bbagen.2019.01.002
  • Peripubertal cannabidiol treatment rescues behavioral and neurochemical abnormalities in the MAM model of schizophrenia, Tibor Stark, Jana Ruda-Kucerova, Fabio Arturo Iannotti, Claudio D'Addario, Roberta Di Marco, Vladimir Pekarik, Eva Drazanova, Fabiana Piscitelli, Monica Bari, Zuzana Babinska, Giovanni Giurdanella, Martina Di Bartolomeo, Salvatore Salomone, Alexandra Sulcova, Mauro Maccarrone, Carsten T. Wotjak, Zenon Starcuk, Filippo Drago, Raphael Mechoulam, Vincenzo Di Marzo, Vincenzo Micale, Neuropharmacology, 2019, 10.1016/j.neuropharm.2018.11.035
  • Systemic administration of serotonin exacerbates abdominal pain and colitis via interaction with the endocannabinoid system, Maciej Salaga, Agata Binienda, Fabiana Piscitelli, Anna Mokrowiecka, Adam I. Cygankiewicz, Roberta Verde, Ewa Malecka-Panas, Radzislaw Kordek, Wanda M. Krajewska, Vincenzo Di Marzo, Jakub Fichna, Biochemical Pharmacology, 2019, 10.1016/j.bcp.2019.01.001
  • In Silico Identification and Experimental Validation of (−)-Muqubilin A, a Marine Norterpene Peroxide, as PPARα/γ-RXRα Agonist and RARα Positive Allosteric Modulator, Enrico D’Aniello, fabio iannotti, Lauren G. Falkenberg, Andrea Martella, Alessandra Gentile, Fabrizia De Maio, Maria Letizia Ciavatta, Margherita Gavagnin, Joshua Waxman, Vincenzo Di Marzo, Pietro Amodeo, ROSA MARIA VITALE, Marine Drugs, 2019, 10.3390/md17020110
  • Effects of diisononyl phthalate (DiNP) on the endocannabinoid and reproductive systems of male gilthead sea bream (Sparus aurata) during the spawning season, Isabel Forner-Piquer, Constantinos C. Mylonas, Ioannis Fakriadis, Maria Papadaki, Fabiana Piscitelli, Vincenzo Di Marzo, Josep Calduch-Giner, Jaume Pérez-Sánchez, Oliana Carnevali, Archives of Toxicology, 2019, 10.1007/s00204-018-2378-6
  • Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis, Amandine Everard, Hubert Plovier, Marialetizia Rastelli, Matthias Van Hul, Alice de Wouters d’Oplinter, Lucie Geurts, Céline Druart, Sylvie Robine, Nathalie M. Delzenne, Giulio G. Muccioli, Willem M. de Vos, Serge Luquet, Nicolas Flamand, Vincenzo Di Marzo, Patrice D. Cani, Nature Communications, 2019, 10.1038/s41467-018-08051-7
  • Synthesis of novel 2-(1-adamantanylcarboxamido)thiophene derivatives. Selective cannabinoid type 2 (CB2) receptor agonists as potential agents for the treatment of skin inflammatory disease, Claudia Mugnaini, Alessandro Rabbito, Antonella Brizzi, Nastasja Palombi, Stefania Petrosino, Roberta Verde, Vincenzo Di Marzo, Alessia Ligresti, Federico Corelli, European Journal of Medicinal Chemistry, 2019, 10.1016/j.ejmech.2018.09.070
  • Ultra-micronized palmitoylethanolamide rescues the cognitive decline-associated loss of neural plasticity in the neuropathic mouse entorhinal cortex-dentate gyrus pathway, Serena Boccella, Claudia Cristiano, Rosaria Romano, Monica Iannotta, Carmela Belardo, Antonio Farina, Francesca Guida, Fabiana Piscitelli, Enza Palazzo, Mariacristina Mazzitelli, Roberta Imperatore, Lea Tunisi, Vito de Novellis, Luigia Cristino, Vincenzo Di Marzo, Antonio Calignano, Sabatino Maione, Livio Luongo, Neurobiology of Disease, 2019, 10.1016/j.nbd.2018.09.023
  • Reversal of albuminuria by combined AM6545 and perindopril therapy in experimental diabetic nephropathy, F Barutta, S Bellini, R Mastrocola, R Gambino, F Piscitelli, V di Marzo, B Corbetta, VK Vemuri, A Makriyannis, L Annaratone, G Bruno, G Gruden, British Journal of Pharmacology, 2018, 10.1111/bph.14495
  • Fishing for Targets of Alien Metabolites: A Novel Peroxisome Proliferator-Activated Receptor (PPAR) Agonist from a Marine Pest, Rosa Maria Vitale, Enrico D'Aniello, Stefania Gorbi, Andrea Martella, Cristoforo Silvestri, Maria Elisa Giuliani, Tariq Fellous, Alessandra Gentile, Marianna Carbone, Adele Cutignano, Laura Grauso, Laura Magliozzi, Gianluca Polese, BIAGIO D'ANIELLO, Fanny Defranoux, Serena Felline, Antonio Terlizzi, Antonio Calignano, Francesco Regoli, Vincenzo Di Marzo, Pietro Amodeo, Ernesto Mollo, Marine Drugs, 2018, 10.3390/md16110431
  • 5th EFLM-UEMS European Joint Congress in Laboratory Medicine, , Clinical Chemistry and Laboratory Medicine (CCLM), 2018, 10.1515/cclm-2018-1038
  • Disruption of the gonadal endocannabinoid system in zebrafish exposed to diisononyl phthalate, Isabel Forner-Piquer, Stefania Santangeli, Francesca Maradonna, Alessandro Rabbito, Fabiana Piscitelli, Hamid R. Habibi, Vincenzo Di Marzo, Oliana Carnevali, Environmental Pollution, 2018, 10.1016/j.envpol.2018.05.007
  • Endocrine disruptors in the diet of male Sparus aurata: Modulation of the endocannabinoid system at the hepatic and central level by Di-isononyl phthalate and Bisphenol A, Isabel Forner-Piquer, Constantinos C. Mylonas, Josep Calduch-Giner, Francesca Maradonna, Giorgia Gioacchini, Marco Allarà, Fabiana Piscitelli, Vincenzo Di Marzo, Jaume Pérez-Sánchez, Oliana Carnevali, Environment International, 2018, 10.1016/j.envint.2018.06.011
  • Δ9-tetrahydrocannabivarin impairs epithelial calcium transport through inhibition of TRPV5 and TRPV6, Annelies Janssens, Cristoforo Silvestri, Andrea Martella, Jo M. Vanoevelen, Vincenzo Di Marzo, Thomas Voets, Pharmacological Research, 2018, 10.1016/j.phrs.2018.08.021
  • Elongation of the Hydrophobic Chain as a Molecular Switch: Discovery of Capsaicin Derivatives and Endogenous Lipids as Potent Transient Receptor Potential Vanilloid Channel 2 Antagonists, Aniello Schiano Moriello, Silvia López Chinarro, Olalla Novo Fernández, Jordi Eras, Pietro Amodeo, Ramon Canela-Garayoa, Rosa Maria Vitale, Vincenzo Di Marzo, Luciano De Petrocellis, Journal of Medicinal Chemistry, 2018, 10.1021/acs.jmedchem.8b00734
  • Effects of non-euphoric plant cannabinoids on muscle quality and performance of dystrophic mdx mice, Fabio Arturo Iannotti, Ester Pagano, Aniello Schiano Moriello, Filomena Grazia Alvino, Nicolina Cristina Sorrentino, Luca D'Orsi, Elisabetta Gazzerro, Raffaele Capasso, Elvira De Leonibus, Luciano De Petrocellis, Vincenzo Di Marzo, British Journal of Pharmacology, 2018, 10.1111/bph.14460
  • Author Correction: CB1 receptor activation induces intracellular Ca2+ mobilization and 2-arachidonoylglycerol release in rodent spinal cord astrocytes, Zoltán Hegyi, Tamás Oláh, Áron Kőszeghy, Fabiana Piscitelli, Krisztina Holló, Balázs Pál, László Csernoch, Vincenzo Di Marzo, Miklós Antal, Scientific Reports, 2018, 10.1038/s41598-018-30573-9
  • FAAH-Catalyzed C–C Bond Cleavage of a New Multitarget Analgesic Drug, Alessia Ligresti, Cristoforo Silvestri, Rosa Maria Vitale, Jose L. Martos, Fabiana Piscitelli, Jenny W. Wang, Marco Allarà, Robert W. Carling, Livio Luongo, Francesca Guida, Anna Illiano, Angela Amoresano, Sabatino Maione, Pietro Amodeo, David F. Woodward, Vincenzo Di Marzo, Gennaro Marino, ACS Chemical Neuroscience, 2018, 10.1021/acschemneuro.8b00315
  • Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy, Fabio A. Iannotti, Ester Pagano, Ombretta Guardiola, Simone Adinolfi, Valentina Saccone, Silvia Consalvi, Fabiana Piscitelli, Elisabetta Gazzerro, Giuseppe Busetto, Diego Carrella, Raffaele Capasso, Pier Lorenzo Puri, Gabriella Minchiotti, Vincenzo Di Marzo, Nature Communications, 2018, 10.1038/s41467-018-06267-1
  • Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain, Margherita Brindisi, Giuseppe Borrelli, Simone Brogi, Alessandro Grillo, Samuele Maramai, Marco Paolino, Mascia Benedusi, Alessandra Pecorelli, Giuseppe Valacchi, Lorenzo Di Cesare Mannelli, Carla Ghelardini, Marco Allarà, Alessia Ligresti, Patrizia Minetti, Giuseppe Campiani, Vincenzo di Marzo, Stefania Butini, Sandra Gemma, ChemMedChem, 2018, 10.1002/cmdc.201800397
  • Endocannabinoid Tone Regulates Human Sebocyte Biology, Nóra Zákány, Attila Oláh, Arnold Markovics, Erika Takács, Andrea Aranyász, Simon Nicolussi, Fabiana Piscitelli, Marco Allarà, Ágnes Pór, Ilona Kovács, Christos C. Zouboulis, Jürg Gertsch, Vincenzo Di Marzo, Tamás Bíró, Tamás Szabó, Journal of Investigative Dermatology, 2018, 10.1016/j.jid.2018.02.022
  • Experimental ischemia/reperfusion model impairs endocannabinoid signaling and Na+/K+ ATPase expression and activity in kidney proximal tubule cells, Luzia S. Sampaio, Fabio A. Iannotti, Luciana Veneziani, Rosa T. Borelli-Tôrres, Fabrizia De Maio, Fabiana Piscitelli, Ricardo A.M. Reis, Vincenzo Di Marzo, Marcelo Einicker-Lamas, Biochemical Pharmacology, 2018, 10.1016/j.bcp.2018.06.005
  • New approaches and challenges to targeting the endocannabinoid system, Vincenzo Di Marzo, Nature Reviews Drug Discovery, 2018, 10.1038/nrd.2018.115
  • Role of Bisphenol A on the Endocannabinoid System at central and peripheral levels: Effects on adult female zebrafish, Isabel Forner-Piquer, Stefania Santangeli, Francesca Maradonna, Roberta Verde, Fabiana Piscitelli, Vincenzo di Marzo, Hamid R. Habibi, Oliana Carnevali, Chemosphere, 2018, 10.1016/j.chemosphere.2018.04.078
  • CB1 receptor activation induces intracellular Ca2+ mobilization and 2-arachidonoylglycerol release in rodent spinal cord astrocytes, Zoltán Hegyi, Tamás Oláh, Áron Kőszeghy, Fabiana Piscitelli, Krisztina Holló, Balázs Pál, László Csernoch, Vincenzo Di Marzo, Miklós Antal, Scientific Reports, 2018, 10.1038/s41598-018-28763-6
  • Overlapping Distribution of Orexin and Endocannabinoid Receptors and Their Functional Interaction in the Brain of Adult Zebrafish, Roberta Imperatore, Livia D’Angelo, Omid Safari, Hamidreza Ahmadniaye Motlagh, Fabiana Piscitelli, Paolo de Girolamo, Luigia Cristino, Ettore Varricchio, Vincenzo di Marzo, Marina Paolucci, Frontiers in Neuroanatomy, 2018, 10.3389/fnana.2018.00062
  • The Involvement of the Endocannabinoid System in the Peripheral Antinociceptive Action of Ketamine, Renata C.M. Ferreira, Marina G.M. Castor, Fabiana Piscitelli, Vincenzo Di Marzo, Igor D.G. Duarte, Thiago R.L. Romero, The Journal of Pain, 2018, 10.1016/j.jpain.2017.12.002
  • Anti-inflammatory Properties of Cannabidiol, a Nonpsychotropic Cannabinoid, in Experimental Allergic Contact Dermatitis, Stefania Petrosino, Roberta Verde, Massimo Vaia, Marco Allarà, Teresa Iuvone, Vincenzo Di Marzo, Journal of Pharmacology and Experimental Therapeutics, 2018, 10.1124/jpet.117.244368
  • Oral Ultramicronized Palmitoylethanolamide: Plasma and Tissue Levels and Spinal Anti-hyperalgesic Effect, Stefania Petrosino, Marika Cordaro, Roberta Verde, Aniello Schiano Moriello, Gabriele Marcolongo, Carlo Schievano, Rosalba Siracusa, Fabiana Piscitelli, Alessio F. Peritore, Rosalia Crupi, Daniela Impellizzeri, Emanuela Esposito, Salvatore Cuzzocrea, Vincenzo Di Marzo, Frontiers in Pharmacology, 2018, 10.3389/fphar.2018.00249
  • Antibiotic-induced microbiota perturbation causes gut endocannabinoidome changes, hippocampal neuroglial reorganization and depression in mice, F. Guida, F. Turco, M. Iannotta, D. De Gregorio, I. Palumbo, G. Sarnelli, A. Furiano, F. Napolitano, S. Boccella, L. Luongo, M. Mazzitelli, A. Usiello, F. De Filippis, F.A. Iannotti, F. Piscitelli, D. Ercolini, V. de Novellis, V. Di Marzo, R. Cuomo, S. Maione, Brain, Behavior, and Immunity, 2018, 10.1016/j.bbi.2017.09.001
  • Effects of repeated long-term psychosocial stress and acute cannabinoid exposure on mouse corticostriatal circuitries: Implications for neuropsychiatric disorders, Jordi Tomas-Roig, Fabiana Piscitelli, Vanesa Gil, Ester Quintana, Lluís l. Ramió-Torrentà, Jose Antonio del Río, Timothy Patrick Moore, Hope Agbemenyah, Gabriela Salinas, Claudia Pommerenke, Stephan Lorenzen, Tim Beißbarth, Sigrid Hoyer-Fender, Vincenzo Di Marzo, Ursula Havemann-Reinecke, CNS Neuroscience & Therapeutics, 2018, 10.1111/cns.12810
  • Peripheral Endocannabinoid Responses to Hedonic Eating in Binge-Eating Disorder, , Nutrients, 2017, 10.3390/nu9121377
  • Characterization of endocannabinoids and related acylethanolamides in the synovial fluid of dogs with osteoarthritis: a pilot study, Carmela Valastro, Debora Campanile, Mariarosaria Marinaro, Delia Franchini, Fabiana Piscitelli, Roberta Verde, Vincenzo Di Marzo, Antonio Di Bello, BMC Veterinary Research, 2017, 10.1186/s12917-017-1245-7
  • Effects of curcumin and curcumin analogues on TRP channels, Marianna Nalli, Giorgio Ortar, Aniello Schiano Moriello, Vincenzo Di Marzo, Luciano De Petrocellis, Fitoterapia, 2017, 10.1016/j.fitote.2017.09.007
  • Dose-Specific Effects of Di-Isononyl Phthalate on the Endocannabinoid System and on Liver of Female Zebrafish, Isabel Forner-Piquer, Francesca Maradonna, Giorgia Gioacchini, Stefania Santangeli, Marco Allarà, Fabiana Piscitelli, Hamid R Habibi, Vincenzo Di Marzo, Oliana Carnevali, Endocrinology, 2017, 10.1210/en.2017-00458
  • Targeting fatty acid amide hydrolase and transient receptor potential vanilloid-1 simultaneously to modulate colonic motility and visceral sensation in the mouse: A pharmacological intervention with N-arachidonoyl-serotonin (AA-5-HT), M. Bashashati, J. Fichna, F. Piscitelli, R. Capasso, A. A. Izzo, A. Sibaev, J.-P. Timmermans, N. Cenac, N. Vergnolle, V. Di Marzo, M. Storr, Neurogastroenterology & Motility, 2017, 10.1111/nmo.13148
  • Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474, Annelot C. M. van Esbroeck, Antonius P. A. Janssen, Armand B. Cognetta, Daisuke Ogasawara, Guy Shpak, Mark van der Kroeg, Vasudev Kantae, Marc P. Baggelaar, Femke M. S. de Vrij, Hui Deng, Marco Allarà, Filomena Fezza, Zhanmin Lin, Tom van der Wel, Marjolein Soethoudt, Elliot D. Mock, Hans den Dulk, Ilse L. Baak, Bogdan I. Florea, Giel Hendriks, Luciano De Petrocellis, Herman S. Overkleeft, Thomas Hankemeier, Chris I. De Zeeuw, Vincenzo Di Marzo, Mauro Maccarrone, Benjamin F. Cravatt, Steven A. Kushner, Mario van der Stelt, Science, 2017, 10.1126/science.aaf7497
  • A TRPV 1‐to‐secretagogin regulatory axis controls pancreatic β‐cell survival by modulating protein turnover, Katarzyna Malenczyk, Fatima Girach, Edit Szodorai, Petter Storm, Åsa Segerstolpe, Giuseppe Tortoriello, Robert Schnell, Jan Mulder, Roman A Romanov, Erzsébet Borók, Fabiana Piscitelli, Vincenzo Di Marzo, Gábor Szabó, Rickard Sandberg, Stefan Kubicek, Gert Lubec, Tomas Hökfelt, Ludwig Wagner, Leif Groop, Tibor Harkany, The EMBO Journal, 2017, 10.15252/embj.201695347
  • Endocannabinoid-dependent disinhibition of orexinergic neurons: Electrophysiological evidence in leptin-knockout obese mice, Thorsten Michael Becker, Morgana Favero, Vincenzo Di Marzo, Luigia Cristino, Giuseppe Busetto, Molecular Metabolism, 2017, 10.1016/j.molmet.2017.04.005
  • Hedonic eating in Prader–Willi syndrome is associated with blunted PYY secretion, A. E. Rigamonti, S. Bini, F. Piscitelli, A. Lauritano, V. Di Marzo, C. Vanetti, F. Agosti, A. De Col, E. Lucchetti, G. Grugni, A. Sartorio, Food & Nutrition Research, 2017, 10.1080/16546628.2017.1297553
  • Participants with Normal Weight or with Obesity Show Different Relationships of 6-n-Propylthiouracil (PROP) Taster Status with BMI and Plasma Endocannabinoids, Gianfranca Carta, Melania Melis, Stefano Pintus, Paolo Pintus, Carla A. Piras, Laura Muredda, Daniela Demurtas, Vincenzo Di Marzo, Sebastiano Banni, Iole Tomassini Barbarossa, Scientific Reports, 2017, 10.1038/s41598-017-01562-1
  • 2-Pentadecyl-2-Oxazoline, the Oxazoline of Pea, Modulates Carrageenan-Induced Acute Inflammation, Stefania Petrosino, Michela Campolo, Daniela Impellizzeri, Irene Paterniti, Marco Allarà, Enrico Gugliandolo, Ramona D’Amico, Rosalba Siracusa, Marika Cordaro, Emanuela Esposito, Vincenzo Di Marzo, Salvatore Cuzzocrea, Frontiers in Pharmacology, 2017, 10.3389/fphar.2017.00308
  • Allodynia Lowering Induced by Cannabinoids and Endocannabinoids (ALICE), Livio Luongo, Katarzyna Starowicz, Sabatino Maione, Vincenzo Di Marzo, Pharmacological Research, 2017, 10.1016/j.phrs.2017.02.019
  • Pharmacological inhibition of MAGL attenuates experimental colon carcinogenesis, Ester Pagano, Francesca Borrelli, Pierangelo Orlando, Barbara Romano, Martina Monti, Lucia Morbidelli, Gabriella Aviello, Roberta Imperatore, Raffaele Capasso, Fabiana Piscitelli, Lorena Buono, Vincenzo Di Marzo, Angelo A. Izzo, Pharmacological Research, 2017, 10.1016/j.phrs.2017.02.002
  • Role of N-Arachidonoyl-Serotonin (AA-5-HT) in Sleep-Wake Cycle Architecture, Sleep Homeostasis, and Neurotransmitters Regulation, Eric Murillo-Rodríguez, Vincenzo Di Marzo, Sergio Machado, Nuno B. Rocha, André B. Veras, Geraldo A. M. Neto, Henning Budde, Oscar Arias-Carrión, Gloria Arankowsky-Sandoval, Frontiers in Molecular Neuroscience, 2017, 10.3389/fnmol.2017.00152
  • The Endocannabinoid System in Leptin-Driven Changes of Orexinergic Signaling Under Physiological and Pathological Conditions, Luigia Cristino, Roberta Imperatore, Letizia Palomba, Vincenzo Di Marzo, Endocannabinoids and Lipid Mediators in Brain Functions, 2017, 10.1007/978-3-319-57371-7_1
  • Dual therapy targeting the endocannabinoid system prevents experimental diabetic nephropathy, Federica Barutta, Serena Grimaldi, Roberto Gambino, Kiran Vemuri, Alexandros Makriyannis, Laura Annaratone, Vincenzo di Marzo, Graziella Bruno, Gabriella Gruden, Nephrology Dialysis Transplantation, 2017, 10.1093/ndt/gfx010
  • Development of a Rapid LC-MS/MS Method for the Quantification of Cannabidiol, Cannabidivarin, Δ9-Tetrahydrocannabivarin, and Cannabigerol in Mouse Peripheral Tissues, Fabiana Piscitelli, Ester Pagano, Anna Lauritano, Angelo A. Izzo, Vincenzo Di Marzo, Analytical Chemistry, 2017, 10.1021/acs.analchem.7b01094
  • CB 1 Cannabinoid Receptors Mediate Cognitive Deficits and Structural Plasticity Changes During Nicotine Withdrawal, Rocio Saravia, África Flores, Ainhoa Plaza-Zabala, Arnau Busquets-Garcia, Antoni Pastor, Rafael de la Torre, Vincenzo Di Marzo, Giovanni Marsicano, Andrés Ozaita, Rafael Maldonado, Fernando Berrendero, Biological Psychiatry, 2017, 10.1016/j.biopsych.2016.07.007
  • Combined CoMFA and CoMSIA 3D-QSAR study of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor, Javier Romero-Parra, Hery Chung, Ricardo A. Tapia, Mario Faúndez, Cesar Morales-Verdejo, Marcos Lorca, Carlos F. Lagos, Vincenzo Di Marzo, C. David Pessoa-Mahana, Jaime Mella, European Journal of Pharmaceutical Sciences, 2017, 10.1016/j.ejps.2017.01.037
  • Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: involvement of the CB2 receptor, F. Guida, L. Luongo, S. Boccella, M. E. Giordano, R. Romano, G. Bellini, I. Manzo, A. Furiano, A. Rizzo, R. Imperatore, F. A. Iannotti, E. D’Aniello, F. Piscitelli, F. sca Rossi, L. Cristino, V. Di Marzo, V. de Novellis, S. Maione, Scientific Reports, 2017, 10.1038/s41598-017-00342-1
  • Plasma palmitoylethanolamide (PEA) as a potential biomarker for impaired coronary function, Alessandra Quercioli, Federico Carbone, Aldo Bonaventura, Luca Liberale, Zoltan Pataky, Aurélien Thomas, Sébastien Lenglet, Estelle Lauer, Alain Golay, Franco Dallegri, Vincenzo Di Marzo, Thomas H. Schindler, Fabrizio Montecucco, International Journal of Cardiology, 2017, 10.1016/j.ijcard.2016.12.023
  • Randomised clinical trial: the analgesic properties of dietary supplementation with palmitoylethanolamide and polydatin in irritable bowel syndrome, C. Cremon, V. Stanghellini, M. R. Barbaro, R. F. Cogliandro, L. Bellacosa, J. Santos, M. Vicario, M. Pigrau, C. Alonso Cotoner, B. Lobo, F. Azpiroz, S. Bruley des Varannes, M. Neunlist, D. DeFilippis, T. Iuvone, S. Petrosino, V. Di Marzo, G. Barbara, Alimentary Pharmacology & Therapeutics, 2017, 10.1111/apt.13958
  • Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity, Marjolein Soethoudt, Uwe Grether, Jürgen Fingerle, Travis W. Grim, Filomena Fezza, Luciano de Petrocellis, Christoph Ullmer, Benno Rothenhäusler, Camille Perret, Noortje van Gils, David Finlay, Christa MacDonald, Andrea Chicca, Marianela Dalghi Gens, Jordyn Stuart, Henk de Vries, Nicolina Mastrangelo, Lizi Xia, Georgios Alachouzos, Marc P. Baggelaar, Andrea Martella, Elliot D. Mock, Hui Deng, Laura H. Heitman, Mark Connor, Vincenzo Di Marzo, Jürg Gertsch, Aron H. Lichtman, Mauro Maccarrone, Pal Pacher, Michelle Glass, Mario van der Stelt, Nature Communications, 2017, 10.1038/ncomms13958
  • Palmitoylethanolamide Supplementation during Sensitization Prevents Airway Allergic Symptoms in the Mouse, Fiorentina Roviezzo, Antonietta Rossi, Elisabetta Caiazzo, Pierangelo Orlando, Maria A. Riemma, Valentina M. Iacono, Andrea Guarino, Armando Ialenti, Carla Cicala, Alessio Peritore, Raffaele Capasso, Vincenzo Di Marzo, Angelo A. Izzo, Frontiers in Pharmacology, 2017, 10.3389/fphar.2017.00857
  • Polymorphism rs1761667 in the CD36 Gene Is Associated to Changes in Fatty Acid Metabolism and Circulating Endocannabinoid Levels Distinctively in Normal Weight and Obese Subjects, Melania Melis, Gianfranca Carta, Stefano Pintus, Paolo Pintus, Carla A. Piras, Elisabetta Murru, Claudia Manca, Vincenzo Di Marzo, Sebastiano Banni, Iole Tomassini Barbarossa, Frontiers in Physiology, 2017, 10.3389/fphys.2017.01006
  • Role of the endocannabinoid system in the control of mouse myometrium contractility during the menstrual cycle, Ester Pagano, Pierangelo Orlando, Stefania Finizio, Antonietta Rossi, Lorena Buono, Fabio Arturo Iannotti, Fabiana Piscitelli, Angelo A. Izzo, Vincenzo Di Marzo, Francesca Borrelli, Biochemical Pharmacology, 2017, 10.1016/j.bcp.2016.11.023
  • Techniques for the Cellular and Subcellular Localization of Endocannabinoid Receptors and Enzymes in the Mammalian Brain, Luigia Cristino, Roberta Imperatore, Vincenzo Di Marzo, Methods in Enzymology, 2017, 10.1016/bs.mie.2017.05.003
  • The time course of erythrocyte membrane fatty acid concentrations during and after treatment of non-human primates with increasing doses of an omega-3 rich phospholipid preparation derived from krill-oil, Petter-Arnt Hals, Xiaoli Wang, Fabiana Piscitelli, Vincenzo Di Marzo, Yong-Fu Xiao, Lipids in Health and Disease, 2017, 10.1186/s12944-017-0414-9
  • The pharmacology of palmitoylethanolamide and first data on the therapeutic efficacy of some of its new formulations, Stefania Petrosino, Vincenzo Di Marzo, British Journal of Pharmacology, 2016, 10.1111/bph.13580
  • Adelmidrol increases the endogenous concentrations of palmitoylethanolamide in canine keratinocytes and down-regulates an inflammatory reaction in an in vitro model of contact allergic dermatitis, Petrosino, S., Puigdemont, A., della Valle, M.F., Fusco, M., Verde, R., Allarà, M., Aveta, T., Orlando, P., Di Marzo, V., Veterinary Journal, 2016, 10.1016/j.tvjl.2015.10.060
  • Anandamide interferes with human endometrial stromal-derived cell differentiation: An effect dependent on inhibition of cyclooxygenase-2 expression and prostaglandin E2 release, Almada, M., Cunha, S., Fonseca, B.M., Amaral, C., Piscitelli, F., Di Marzo, V., Correia-da-Silva, G., Teixeira, N., BioFactors, 2016, 10.1002/biof.1270
  • Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells, Fiore, D., Proto, M.C., Pisanti, S., Picardi, P., Pagano Zottola, A.C., Butini, S., Gemma, S., Casagni, A., Laezza, C., Vitale, M., Ligresti, A., Di Marzo, V., Zisterer, D.M., Nathwani, S., Williams, D.C., Campiani, G., Gazzerro, P., Bifulco, M., Cancer Biology and Therapy, 2016, 10.1080/15384047.2015.1078028
  • Arylboronic acids as dual-action FAAH and TRPV1 ligands, Morera, E., Di Marzo, V., Monti, L., Allarà, M., Schiano Moriello, A., Nalli, M., Ortar, G., De Petrocellis, L., Bioorganic and Medicinal Chemistry Letters, 2016, 10.1016/j.bmcl.2016.01.071
  • At the tip of an iceberg: Prenatal marijuana and its possible relation to neuropsychiatric outcome in the offspring, Alpár, A., Di Marzo, V., Harkany, T., Biological Psychiatry, 2016, 10.1016/j.biopsych.2015.09.009
  • Bisphenol a induces fatty liver by an endocannabinoid-mediated positive feedback loop, Martella, A., Silvestri, C., Maradonna, F., Gioacchini, G., Allara, M., Radaelli, G., Overby, D.R., Di Marzo, V., Carnevali, O., Endocrinology, 2016, 10.1210/en.2015-1384
  • Chalcone derivatives activate and desensitize the transient receptor potential ankyrin 1 cation channel, subfamily A, member 1 TRPA1 ion channel: Structure-activity relationships in vitro and anti-nociceptive and anti-inflammatory activity in vivo, Moriello, A.S., Luongo, L., Guida, F., Christodoulou, M.S., Perdicchia, D., Maione, S., Passarella, D., Di Marzo, V., De Petrocellis, L., CNS and Neurological Disorders - Drug Targets, 2016, 10.1016/j.ienj.2015.05.007
  • Chronic exposure to cannabinoids during adolescence causes long-lasting behavioral deficits in adult mice, Tomas-Roig, J., Benito, E., Agis-Balboa, R., Piscitelli, F., Hoyer-Fender, S., Di Marzo, V., Havemann-Reinecke, U., Addiction Biology, 2016, 10.1111/adb.12446
  • Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress, Aiello, F., Badolato, M., Pessina, F., Sticozzi, C., Maestrini, V., Aldinucci, C., Luongo, L., Guida, F., Ligresti, A., Artese, A., Allarà, M., Costa, G., Frosini, M., Schiano Moriello, A., De Petrocellis, L., Valacchi, G., Alcaro, S., Maione, S., Di Marzo, V., Corelli, F., Brizzi, A., ACS Chemical Neuroscience, 2016, 10.1021/acschemneuro.5b00333
  • Development and Pharmacological Characterization of Selective Blockers of 2-Arachidonoyl Glycerol Degradation with Efficacy in Rodent Models of Multiple Sclerosis and Pain, Brindisi, M., Maramai, S., Gemma, S., Brogi, S., Grillo, A., Di Cesare Mannelli, L., Gabellieri, E., Lamponi, S., Saponara, S., Gorelli, B., Tedesco, D., Bonfiglio, T., Landry, C., Jung, K.-M., Armirotti, A., Luongo, L., Ligresti, A., Piscitelli, F., Bertucci, C., Dehouck, M.-P., Campiani, G., Maione, S., Ghelardini, C., Pittaluga, A., Piomelli, D., Di Marzo, V., Butini, S., Journal of Medicinal Chemistry, 2016, 10.1021/acs.jmedchem.5b01812
  • Discovery of novel Tetrahydrobenzo[b]thiophene and pyrrole based scaffolds as potent and selective CB2 receptor ligands: The structural elements controlling binding affinity, selectivity and functionality, Osman, N.A., Ligresti, A., Klein, C.D., Allarà, M., Rabbito, A., Di Marzo, V., Abouzid, K.A., Abadi, A.H., European Journal of Medicinal Chemistry, 2016, 10.1016/j.ejmech.2016.07.012
  • Early low-fat diet enriched with linolenic acid reduces liver endocannabinoid tone and improves late glycemic control after a high-fat diet challenge in mice, Demizieux, L., Piscitelli, F., Troy-Fioramonti, S., Iannotti, F.A., Borrino, S., Gresti, J., Muller, T., Bellenger, J., Silvestri, C., Di Marzo, V., Degrace, P., Diabetes, 2016, 10.2337/db15-1279
  • Effects of chronic exercise on the endocannabinoid system in Wistar rats with high-fat diet-induced obesity, Gamelin, F.-X., Aucouturier, J., Iannotti, F.A., Piscitelli, F., Mazzarella, E., Aveta, T., Leriche, M., Dupont, E., Cieniewski-Bernard, C., Montel, V., Bastide, B., Di Marzo, V., Heyman, E., Journal of Physiology and Biochemistry, 2016, 10.1007/s13105-016-0469-5
  • Elevated Systemic Levels of Endocannabinoids and Related Mediators Across the Menstrual Cycle in Women with Endometriosis, Sanchez, A.M., Cioffi, R., Viganò, P., Candiani, M., Verde, R., Piscitelli, F., Di Marzo, V., Garavaglia, E., Panina-Bordignon, P., Reproductive Sciences, 2016, 10.1177/1933719116630414
  • Endocannabinoid regulation in white and brown adipose tissue following thermogenic activation, Krott, L.M., Piscitelli, F., Heine, M., Borrino, S., Scheja, L., Silvestri, C., Heeren, J., Di Marzo, V., Journal of Lipid Research, 2016, 10.1194/jlr.M065227
  • Endocannabinoids and endocannabinoid-related mediators: Targets, metabolism and role in neurological disorders, Iannotti, F.A., Di Marzo, V., Petrosino, S., Progress in Lipid Research, 2016, 10.1016/j.plipres.2016.02.002
  • Endovanilloid control of pain modulation by the rostroventromedial medulla in an animal model of diabetic neuropathy, Silva, M., Martins, D., Charrua, A., Piscitelli, F., Tavares, I., Morgado, C., Di Marzo, V., Neuropharmacology, 2016, 10.1016/j.neuropharm.2016.03.007
  • Erratum to: Responses of peripheral endocannabinoids and endocannabinoid‑related compounds to hedonic eating in obesity (Eur J Nutr, 2016, DOI 10.1007/s00394-016-1153-9), Monteleone, A.M., Di Marzo, V., Monteleone, P., Dalle Grave, R., Aveta, T., El Ghoch, M., Piscitelli, F., Volpe, U., Calugi, S., Maj, M., European Journal of Nutrition, 2016, 10.1007/s00394-016-1204-2
  • Fatty Acid Amide Hydrolase (FAAH), Acetylcholinesterase (AChE), and Butyrylcholinesterase (BuChE): Networked Targets for the Development of Carbamates as Potential Anti-Alzheimer's Disease Agents, Montanari, S., Scalvini, L., Bartolini, M., Belluti, F., Gobbi, S., Andrisano, V., Ligresti, A., Di Marzo, V., Rivara, S., Mor, M., Bisi, A., Rampa, A., Journal of Medicinal Chemistry, 2016, 10.1021/acs.jmedchem.6b00609
  • From phytocannabinoids to cannabinoid receptors and endocannabinoids: Pleiotropic physiological and pathological roles through complex pharmacology, Ligresti, A., De Petrocellis, L., Di Marzo, V., Physiological Reviews, 2016, 10.1152/physrev.00002.2016
  • Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: Definition of the structural determinants for enzyme inhibition, Brindisi, M., Brogi, S., Maramai, S., Grillo, A., Borrelli, G., Butini, S., Novellino, E., Allarà, M., Ligresti, A., Campiani, G., Di Marzo, V., Gemma, S., RSC Advances, 2016, 10.1039/c6ra12524g
  • Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors, Staiano, R.I., Loffredo, S., Borriello, F., Iannotti, F.A., Piscitelli, F., Orlando, P., Secondo, A., Granata, F., Lepore, M.T., Fiorelli, A., Varricchi, G., Santini, M., Triggiani, M., Di Marzo, V., Marone, G., Journal of Leukocyte Biology, 2016, 10.1189/jlb.3HI1214-584R
  • Investigations on the 4-Quinolone-3-carboxylic Acid Motif. 7. Synthesis and Pharmacological Evaluation of 4-Quinolone-3-carboxamides and 4-Hydroxy-2-quinolone-3-carboxamides as High Affinity Cannabinoid Receptor 2 (CB2R) Ligands with Improved Aqueous Solubility, Mugnaini, C., Brizzi, A., Ligresti, A., Allarà, M., Lamponi, S., Vacondio, F., Silva, C., Mor, M., Di Marzo, V., Corelli, F., Journal of Medicinal Chemistry, 2016, 10.1021/acs.jmedchem.5b01559
  • Orexin-A and endocannabinoid activation of the descending antinociceptive pathway underlies altered pain perception in leptin signaling deficiency, Cristino, L., Luongo, L., Imperatore, R., Boccella, S., Becker, T., Morello, G., Piscitelli, F., Busetto, G., Maione, S., Di Marzo, V., Neuropsychopharmacology, 2016, 10.1038/npp.2015.173
  • Orexin-A represses satiety-inducing POMC neurons and contributes to obesity via stimulation of endocannabinoid signaling, Morello, G., Imperatore, R., Palomba, L., Finelli, C., Labruna, G., Pasanisi, F., Sacchetti, L., Buono, L., Piscitelli, F., Orlando, P., Di Marzo, V., Cristino, L., Proceedings of the National Academy of Sciences of the United States of America, 2016, 10.1073/pnas.1521304113
  • Palmitoylethanolamide reduces inflammation and itch in a mouse model of contact allergic dermatitis, Vaia, M., Petrosino, S., De Filippis, D., Negro, L., Guarino, A., Carnuccio, R., Di Marzo, V., Iuvone, T., European Journal of Pharmacology, 2016, 10.1016/j.ejphar.2016.10.005
  • Responses of peripheral endocannabinoids and endocannabinoid-related compounds to hedonic eating in obesity, Monteleone, A.M., Di Marzo, V., Monteleone, P., Dalle Grave, R., Aveta, T., Ghoch, M.E., Piscitelli, F., Volpe, U., Calugi, S., Maj, M., European Journal of Nutrition, 2016, 10.1007/s00394-016-1153-9
  • Social defeat leads to changes in the endocannabinoid system: An overexpression of calreticulin and motor impairment in mice, Tomas-Roig, J., Piscitelli, F., Gil, V., del Río, J.A., Moore, T.P., Agbemenyah, H., Salinas-Riester, G., Pommerenke, C., Lorenzen, S., Beißbarth, T., Hoyer-Fender, S., Di Marzo, V., Havemann-Reinecke, U., Behavioural Brain Research, 2016, 10.1016/j.bbr.2016.01.036
  • Synthesis, binding assays, cytotoxic activity and docking studies of benzimidazole and benzothiophene derivatives with selective affinity for the CB2 cannabinoid receptor, Romero-Parra, J., Mella-Raipán, J., Palmieri, V., Allarà, M., Torres, M.J., Pessoa-Mahana, H., Iturriaga-Vásquez, P., Escobar, R., Faúndez, M., Di Marzo, V., Pessoa-Mahana, C.D., European Journal of Medicinal Chemistry, 2016, 10.1016/j.ejmech.2016.08.005
  • The anti-inflammatory mediator palmitoylethanolamide enhances the levels of 2-arachidonoyl-glycerol and potentiates its actions at TRPV1 cation channels, Petrosino, S., Schiano Moriello, A., Cerrato, S., Fusco, M., Puigdemont, A., De Petrocellis, L., Di Marzo, V., British Journal of Pharmacology, 2016, 10.1111/bph.13084
  • The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain, Malek, N., Kostrzewa, M., Makuch, W., Pajak, A., Kucharczyk, M., Piscitelli, F., Przewlocka, B., Di Marzo, V., Starowicz, K., Pharmacological Research, 2016, 10.1016/j.phrs.2016.06.012
  • TRPA1 channels as targets for resveratrol and related stilbenoids, Nalli, M., Ortar, G., Moriello, A.S., Morera, E., Di Marzo, V., De Petrocellis, L., Bioorganic and Medicinal Chemistry Letters, 2016, 10.1016/j.bmcl.2015.12.065
  • 2-AG promotes the expression of conditioned fear via cannabinoid receptor type 1 on GABAergic neurons, Llorente-Berzal, A., Terzian, A.L.B., Di Marzo, V., Micale, V., Viveros, M.P., Wotjak, C.T., Psychopharmacology, 2015, 10.1007/s00213-015-3917-y
  • A multi-target approach for pain treatment: Dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis, Malek, N., Mrugala, M., Makuch, W., Kolosowska, N., Przewlocka, B., Binkowski, M., Czaja, M., Morera, E., Di Marzo, V., Starowicz, K., Pain, 2015, 10.1097/j.pain.0000000000000132
  • Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex, Rubino, T., Prini, P., Piscitelli, F., Zamberletti, E., Trusel, M., Melis, M., Sagheddu, C., Ligresti, A., Tonini, R., Di Marzo, V., Parolaro, D., 2015, 10.1016/j.nbd.2014.09.015
  • Anandamide and decidual remodelling: COX-2 oxidative metabolism as a key regulator, Almada, M., Piscitelli, F., Fonseca, B.M., Di Marzo, V., Correia-Da-Silva, G., Teixeira, N., Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 2015, 10.1016/j.bbalip.2015.08.011
  • Anandamide drives cell cycle progression through CB1 receptors in a rat model of synchronized liver regeneration, Pisanti, S., Picardi, P., Pallottini, V., Martini, C., Petrosino, S., Proto, M.C., Vitale, M., Laezza, C., Gazzerro, P., Di Marzo, V., Bifulco, M., Journal of Cellular Physiology, 2015, 10.1002/jcp.24959
  • Anticipatory and consummatory effects of (hedonic) chocolate intake are associated with increased circulating levels of the orexigenic peptide ghrelin and endocannabinoids in obese adults, Rigamonti, A.E., Piscitelli, F., Aveta, T., Agosti, F., De Col, A., Bini, S., Cella, S.G., Di Marzo, V., Sartorio, A., Food and Nutrition Research, 2015, 10.3402/fnr.v59.29678
  • Are cannabidiol and Δ9-tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review, McPartland, J.M., Duncan, M., Di Marzo, V., Pertwee, R.G., 2015, 10.1111/bph.12944
  • Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes, Di Marzo, V., Piscitelli, F., Mechoulam, R., Handbook of Experimental Pharmacology, 2015, 10.1007/978-3-642-17214-4_4
  • Cannabinoids in the Treatment of Neurological Disorders, Devinsky, O., Whalley, B.J., Di Marzo, V., Neurotherapeutics, 2015, 10.1007/s13311-015-0388-0
  • Changes in the endocannabinoid signaling system in CNS structures of TDP-43 transgenic mice: relevance for a neuroprotective therapy in TDP-43-related disorders, Espejo-Porras, F., Piscitelli, F., Verde, R., Ramos, J.A., Di Marzo, V., de Lago, E., Fernández-Ruiz, J., Journal of Neuroimmune Pharmacology, 2015, 10.1007/s11481-015-9602-4
  • Circulating endocannabinoids and the polymorphism 385C>A in fatty acid amide hydrolase (FAAH) gene may identify the obesity phenotype related to cardiometabolic risk: A study conducted in a Brazilian population of complex interethnic admixture, De Moraes Martins, C.J., Genelhu, V., Pimentel, M.M.G., Celoria, B.M.J., Mangia, R.F., Aveta, T., Silvestri, C., Di Marzo, V., Francischetti, E.A., PLoS ONE, 2015, 10.1371/journal.pone.0142728
  • Combining Mass Spectrometric Metabolic Profiling with Genomic Analysis: A Powerful Approach for Discovering Natural Products from Cyanobacteria, Kleigrewe, K., Almaliti, J., Tian, I.Y., Kinnel, R.B., Korobeynikov, A., Monroe, E.A., Duggan, B.M., Di Marzo, V., Sherman, D.H., Dorrestein, P.C., Gerwick, L., Gerwick, W.H., Journal of Natural Products, 2015, 10.1021/acs.jnatprod.5b00301
  • Deranged endocannabinoid responses to hedonic eating in underweight and recently weight-restored patients with anorexia nervosa, Monteleone, A.M., Di Marzo, V., Aveta, T., Piscitelli, F., Dalle Grave, R., Scognamiglio, P., El Ghoch, M., Calugi, S., Monteleone, P., Maj, M., American Journal of Clinical Nutrition, 2015, 10.3945/ajcn.114.096164
  • Diacerein is a potent and selective inhibitor of palmitoylethanolamide inactivation with analgesic activity in a rat model of acute inflammatory pain, Petrosino, S., Ahmad, A., Marcolongo, G., Esposito, E., Allarà, M., Verde, R., Cuzzocrea, S., Di Marzo, V., 2015, 10.1016/j.phrs.2014.10.008
  • Discovery of non-electrophilic capsaicinoid-type TRPA1 ligands, Del Prete, D., Caprioglio, D., Appendino, G., Minassi, A., Schiano-Moriello, A., Di Marzo, V., De Petrocellis, L., Bioorganic and Medicinal Chemistry Letters, 2015, 10.1016/j.bmcl.2015.01.039
  • Distinct Temporal Fingerprint for Cyclic Adenosine Monophosphate (cAMP) Signaling of Indole-2-carboxamides as Allosteric Modulators of the Cannabinoid Receptors, Cawston, E.E., Connor, M., Di Marzo, V., Silvestri, R., Glass, M., Journal of Medicinal Chemistry, 2015, 10.1021/acs.jmedchem.5b00579
  • Editorial, Di Marzo, V., Recent Patents on CNS Drug Discovery, 2015
  • Effects of metabolites of the analgesic agent dipyrone (metamizol) on rostral ventromedial medulla cell activity in mice, Maione, S., Radanova, L., De Gregorio, D., Luongo, L., De Petrocellis, L., Di Marzo, V., Imming, P., 2015, 10.1016/j.ejphar.2014.12.022
  • Elevation of plasma 2-arachidonoylglycerol levels in alzheimer's disease patients as a potential protective mechanism against neurodegenerative decline, Altamura, C., Ventriglia, M., Martini, M.G., Montesano, D., Errante, Y., Piscitelli, F., Scrascia, F., Quattrocchi, C., Palazzo, P., Seccia, S., Vernieri, F., Di Marzo, V., Journal of Alzheimer's Disease, 2015, 10.3233/JAD-142349
  • Endocannabinoid signaling at the periphery: 50 years after THC, Maccarrone, M., Bab, I., Bíró, T., Cabral, G.A., Dey, S.K., Di Marzo, V., Konje, J.C., Kunos, G., Mechoulam, R., Pacher, P., Sharkey, K.A., Zimmer, A., Trends in Pharmacological Sciences, 2015, 10.1016/j.tips.2015.02.008
  • Endocannabinoid signalling and the deteriorating brain, Di Marzo, V., Stella, N., Zimmer, A., Nature Reviews Neuroscience, 2015, 10.1038/nrn3876
  • Erratum to: Cannabinoids in the Treatment of Neurological Disorders(Neurotherapeutics, Doi:10.1007/s13311-015-0388-0), Devinsky, O., Whalley, B.J., Di Marzo, V., Neurotherapeutics, 2015, 10.1007/s13311-015-0392-4
  • Exposure to Allergen Causes Changes in NTS Neural Activities after Intratracheal Capsaicin Application, in Endocannabinoid Levels and in the Glia Morphology of NTS, Giuseppe Spaziano, Livio Luongo, Francesca Guida, Stefania Petrosino, Maria Matteis, Enza Palazzo, Nikol Sullo, Vito de Novellis, Vincenzo Di Marzo, Francesco Rossi, Sabatino Maione, Bruno D’Agostino, BioMed Research International, 2015, 10.1155/2015/980983
  • Genetic deletion of monoacylglycerol lipase leads to impaired cannabinoid receptor CB1R signaling and anxiety-like behavior, Imperatore, R., Morello, G., Luongo, L., Taschler, U., Romano, R., De Gregorio, D., Belardo, C., Maione, S., Di Marzo, V., Cristino, L., Journal of Neurochemistry, 2015, 10.1111/jnc.13267
  • Highly Selective, Reversible Inhibitor Identified by Comparative Chemoproteomics Modulates Diacylglycerol Lipase Activity in Neurons, Baggelaar, M.P., Chameau, P.J.P., Kantae, V., Hummel, J., Hsu, K.-L., Janssen, F., Van Der Wel, T., Soethoudt, M., Deng, H., Den Dulk, H., Allarà, M., Florea, B.I., Di Marzo, V., Wadman, W.J., Kruse, C.G., Overkleeft, H.S., Hankemeier, T., Werkman, T.R., Cravatt, B.F., Van Der Stelt, M., Journal of the American Chemical Society, 2015, 10.1021/jacs.5b04883
  • Inhibiting endocannabinoid biosynthesis: A novel approach to the treatment of constipation, Bashashati, M., Nasser, Y., Keenan, C.M., Ho, W., Piscitelli, F., Nalli, M., Mackie, K., Storr, M.A., Di Marzo, V., Sharkey, K.A., British Journal of Pharmacology, 2015, 10.1111/bph.13114
  • Inhibitory effect of positively charged triazine antagonists of prokineticin receptors on the transient receptor vanilloid type-1 (TRPV1) channel, De Petrocellis, L., Schiano Moriello, A., Byun, J.S., Sohn, J.M., Lee, J.Y., Vázquez-Romero, A., Garrido, M., Messeguer, A., Zhang, F.-X., Zamponi, G.W., Deplano, A., Congiu, C., Onnis, V., Balboni, G., Di Marzo, V., Pharmacological Research, 2015, 10.1016/j.phrs.2015.07.009
  • Meet our editor, Di Marzo, V., Recent Patents on CNS Drug Discovery, 2015
  • Negative regulation of leptin-induced reactive oxygen species (ROS) formation by cannabinoid CB1 receptor activation in hypothalamic neurons, Palomba, L., Silvestri, C., Imperatore, R., Morello, G., Piscitelli, F., Martella, A., Cristino, L., Di Marzo, V., Journal of Biological Chemistry, 2015, 10.1074/jbc.M115.646885
  • New quinolone- and 1,8-naphthyridine-3-carboxamides as selective CB2 receptor agonists with anticancer and immuno-modulatory activity, Manera, C., Malfitano, A.M., Parkkari, T., Lucchesi, V., Carpi, S., Fogli, S., Bertini, S., Laezza, C., Ligresti, A., Saccomanni, G., Savinainen, J.R., Ciaglia, E., Pisanti, S., Gazzerro, P., Di Marzo, V., Nieri, P., Macchia, M., Bifulco, M., European Journal of Medicinal Chemistry, 2015, 10.1016/j.ejmech.2015.04.034
  • Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice, Guida, F., Luongo, L., Marmo, F., Romano, R., Iannotta, M., Napolitano, F., Belardo, C., Marabese, I., D'Aniello, A., De Gregorio, D., Rossi, F., Piscitelli, F., Lattanzi, R., De Bartolomeis, A., Usiello, A., Di Marzo, V., De Novellis, V., Maione, S., Molecular Brain, 2015, 10.1186/s13041-015-0139-5
  • Polypharmacology Shakes Hands with Complex Aetiopathology, Brodie, J.S., Di Marzo, V., Guy, G.W., Trends in Pharmacological Sciences, 2015, 10.1016/j.tips.2015.08.010
  • Protective effect of palmitoylethanolamide in a rat model of cystitis, Pessina, F., Capasso, R., Borrelli, F., Aveta, T., Buono, L., Valacchi, G., Fiorenzani, P., Di Marzo, V., Orlando, P., Izzo, A.A., Journal of Urology, 2015, 10.1016/j.juro.2014.11.083
  • Rational drug design paradigms: The odyssey for designing better drugs, Kellici, T., Ntountaniotis, D., Vrontaki, E., Liapakis, G., Moutevelis-Minakakis, P., Kokotos, G., Hadjikakou, S., Tzakos, A.G., Afantitis, A., Melagraki, G., Bryant, S., Langer, T., Di Marzo, V., Mavromoustakos, T., Combinatorial Chemistry and High Throughput Screening, 2015
  • Role of the endocannabinoid system in obesity induced by neuropeptide y overexpression in noradrenergic neurons, Vähätalo, L.H., Ruohonen, S.T., Mäkelä, S., Ailanen, L., Penttinen, A.-M., Stormi, T., Kauko, T., Piscitelli, F., Silvestri, C., Savontaus, E., Di Marzo, V., Nutrition and Diabetes, 2015, 10.1038/nutd.2015.1
  • Synthesis, biological activity and molecular modeling of new biphenylic carboxamides as potent and selective CB2 receptor ligands, Bertini, S., Parkkari, T., Savinainen, J.R., Arena, C., Saccomanni, G., Saguto, S., Ligresti, A., Allarà, M., Bruno, A., Marinelli, L., Di Marzo, V., Novellino, E., Manera, C., Macchia, M., 2015, 10.1016/j.ejmech.2014.11.066
  • The Endocannabinoid System and its Modulation by Phytocannabinoids, Di Marzo, V., Piscitelli, F., Neurotherapeutics, 2015, 10.1007/s13311-015-0374-6
  • The endocannabinoid system in renal cells: Regulation of Na + transport by CB1 receptors through distinct cell signalling pathways, Sampaio, L.S., Taveira Da Silva, R., Lima, D., Sampaio, C.L.C., Iannotti, F.A., Mazzarella, E., Di Marzo, V., Vieyra, A., Reis, R.A.M., Einicker-Lamas, M., British Journal of Pharmacology, 2015, 10.1111/bph.13050
  • The ever-expanding world of the endocannabinoids: A concise introduction, Piscitelli, F., Di Marzo, V., Cannabinoids in Neurologic and Mental Disease, 2015, 10.1016/B978-0-12-417041-4.00024-2
  • Therapy with a Selective Cannabinoid Receptor Type 2 Agonist Limits Albuminuria and Renal Injury in Mice with Type 2 Diabetic Nephropathy, Zoja, C., Locatelli, M., Corna, D., Villa, S., Rottoli, D., Nava, V., Verde, R., Piscitelli, F., Di Marzo, V., Fingerle, J., Adam, J.-M., Rothenhaeusler, B., Ottaviani, G., Bénardeau, A., Abbate, M., Remuzzi, G., Benigni, A., Nephron, 2015, 10.1159/000442679
  • TRPV1 modulators: Synthesis and in vitro evaluation of 1-heteroaryl piperidinecarboxamide and piperazinylurea derivatives, Congiu, C., Onnis, V., Balboni, G., Schiano-Moriello, A., Di Marzo, V., De Petrocellis, L., European Journal of Medicinal Chemistry, 2015, 10.1016/j.ejmech.2015.05.041
  • Two non-psychoactive cannabinoids reduce intracellular lipid levels and inhibit hepatosteatosis, Silvestri, C., Paris, D., Martella, A., Melck, D., Guadagnino, I., Cawthorne, M., Motta, A., Di Marzo, V., Journal of Hepatology, 2015, 10.1016/j.jhep.2015.01.001
  • 1,2-Dihydro-2-oxopyridine-3-carboxamides: The C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor, Lucchesi, V., Parkkari, T., Savinainen, J.R., Malfitano, A.M., Allarà, M., Bertini, S., Castelli, F., Del Carlo, S., Laezza, C., Ligresti, A., Saccomanni, G., Bifulco, M., Di Marzo, V., Macchia, M., Manera, C., 2014, 10.1016/j.ejmech.2013.10.070
  • Acute resistance exercise induces antinociception by activation of the endocannabinoid system in rats, Galdino, G., Romero, T., Da Silva, J.F.P., Aguiar, D., De Paula, A.M., Cruz, J., Parrella, C., Piscitelli, F., Duarte, I., Di Marzo, V., Perez, A., 2014, 10.1213/ANE.0000000000000340
  • Anandamide produced by Ca2+-insensitive enzymes induces excitation in primary sensory neurons, Varga, A., Jenes, A., Marczylo, T.H., Sousa-Valente, J., Chen, J., Austin, J., Selvarajah, S., Piscitelli, F., Andreou, A.P., Taylor, A.H., Kyle, F., Yaqoob, M., Brain, S., White, J.P.M., Csernoch, L., Di Marzo, V., Buluwela, L., Nagy, I., 2014, 10.1007/s00424-013-1360-7
  • Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders, Devinsky, O., Cilio, M.R., Cross, H., Fernandez-Ruiz, J., French, J., Hill, C., Katz, R., Di Marzo, V., Jutras-Aswad, D., Notcutt, W.G., Martinez-Orgado, J., Robson, P.J., Rohrback, B.G., Thiele, E., Whalley, B., Friedman, D., 2014, 10.1111/epi.12631
  • Cannabinoids and schizophrenia: Therapeutic prospects, Robson, P.J., Guy, G.W., Di Marzo, V., 2014, 10.2174/13816128113199990427
  • Care and feeding of the endocannabinoid system: A systematic review of potential clinical interventions that upregulate the endocannabinoid system, McPartland, J.M., Guy, G.W., Di Marzo, V., 2014, 10.1371/journal.pone.0089566
  • CB2-selective cannabinoid receptor ligands: Synthesis, pharmacological evaluation, and molecular modeling investigation of 1,8-naphthyridin-2(1 H)-one-3-carboxamides, Lucchesi, V., Hurst, D.P., Shore, D.M., Bertini, S., Ehrmann, B.M., Allarà, M., Lawrence, L., Ligresti, A., Minutolo, F., Saccomanni, G., Sharir, H., Macchia, M., Di Marzo, V., Abood, M.E., Reggio, P.H., Manera, C., Journal of Medicinal Chemistry, 2014, 10.1021/jm500807e
  • Circulating endocannabinoids in insulin sensitive vs. Insulin resistant obese postmenopausal women. A MONET group study, Abdulnour, J., Yasari, S., Rabasa-Lhoret, R., Faraj, M., Petrosino, S., Piscitelli, F., Prud'Homme, D., Di Marzo, V., 2014, 10.1002/oby.20498
  • Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice, Barutta, F., Grimaldi, S., Franco, I., Bellini, S., Gambino, R., Pinach, S., Corbelli, A., Bruno, G., Rastaldi, M.P., Aveta, T., Hirsch, E., Di Marzo, V., Gruden, G., 2014, 10.1038/ki.2014.165
  • Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase α and α/β-hydrolase domain 6, Janssen, F.J., Deng, H., Baggelaar, M.P., Allarà, M., Van Der Wel, T., Den Dulk, H., Ligresti, A., Van Esbroeck, A.C.M., McGuire, R., Di Marzo, V., Overkleeft, H.S., Van Der Stelt, M., 2014, 10.1021/jm500681z
  • Editorial, Di Marzo, V., 2014, 10.2174/157488980901140428100532
  • Effect of acyclic monoterpene alcohols and their derivatives on TRP channels, Ortar, G., Schiano Moriello, A., Morera, E., Nalli, M., Di Marzo, V., De Petrocellis, L., 2014, 10.1016/j.bmcl.2014.10.012
  • Effect of chirality and lipophilicity in the functional activity of evodiamine and its analogues at TRPV1 channels, De Petrocellis, L., Schiano Moriello, A., Fontana, G., Sacchetti, A., Passarella, D., Appendino, G., Di Marzo, V., 2014, 10.1111/bph.12320
  • Effect of narrowband ultraviolet B treatment on endocannabinoid plasma levels in patients with psoriasis, Magina, S., Vieira-Coelho, M.A., Moura, E., Serrão, M.P., Piscitelli, F., Moura, D., Di Marzo, V., 2014, 10.1111/bjd.12916
  • Endocannabinoids and energy homeostasis: An update, Cristino, L., Becker, T., Di Marzo, V., 2014, 10.1002/biof.1168
  • Endocannabinoids and neuropathic pain: Focus on neuron-glia and endocannabinoid-neurotrophin interactions, Luongo, L., Maione, S., Di Marzo, V., 2014, 10.1111/ejn.12440
  • Fetal cannabinoid receptors and the "dis-joint-ed" brain, Cristino, L., Di Marzo, V., 2014, 10.1002/embj.201488086
  • Fifty years of 'cannabinoid research' and the need for a new nomenclature, Di Marzo, V., De Petrocellis, L., Cannabinoids, 2014, 10.1002/9781118451281.ch8
  • Glutamate spillover drives endocannabinoid production and inhibits GABAergic transmission in the Substantia Nigra pars compacta, Freestone, P.S., Guatteo, E., Piscitelli, F., Di Marzo, V., Lipski, J., Mercuri, N.B., 2014, 10.1016/j.neuropharm.2013.12.007
  • Increased levels of palmitoylethanolamide and other bioactive lipid mediators and enhanced local mast cell proliferation in canine atopic dermatitis, Abramo, F., Campora, L., Albanese, F., della Valle, M.F., Cristino, L., Petrosino, S., Di Marzo, V., Miragliotta, V., 2014, 10.1186/1746-6148-10-21
  • Iron overload causes osteoporosis in thalassemia major patients through interaction with transient receptor potential vanilloid type 1 (TRPV1) channels, Rossi, F., Perrotta, S., Bellini, G., Luongo, L., Tortora, C., Siniscalco, D., Francese, M., Torella, M., Nobili, B., Di Marzo, V., Maione, S., 2014, 10.3324/haematol.2014.104463
  • Mooreamide A: A cannabinomimetic lipid from the marine cyanobacterium Moorea bouillonii, Mevers, E., Matainaho, T., Allara', M., Di Marzo, V., Gerwick, W.H., 2014, 10.1007/s11745-014-3949-9
  • N-Acyldopamines and N-Acylserotonins: From Synthetic Pharmacological Tools to Endogenous Multitarget Mediators, De Petrocellis, L., Di Marzo, V., The Endocannabinoidome: The World of Endocannabinoids and Related Mediators, 2014, 10.1016/B978-0-12-420126-2.00005-5
  • Naphthalene and 2,3-dihydrobenzo[b][1,4]dioxine derivatives with extended side chains as new scaffolds of CB2-selective ligands, Osman, N.A., Mahmoud, A.H., Klein, C.D., Allarà, M., Di Marzo, V., Abouzid, K.M., Abadi, A.H., 2014, 10.1039/c4md00232f
  • Nonpsychotropic plant cannabinoids, Cannabidivarin (CBDV) and Cannabidiol (CBD), activate and desensitize Transient Receptor Potential Vanilloid 1 (TRPV1) channels in vitro: Potential for the treatment of neuronal hyperexcitability, Iannotti, F.A., Hill, C.L., Leo, A., Alhusaini, A., Soubrane, C., Mazzarella, E., Russo, E., Whalley, B.J., Di Marzo, V., Stephens, G.J., 2014, 10.1021/cn5000524
  • Palmitoylethanolamide normalizes intestinal motility in a model of post-inflammatory accelerated transit: Involvement of CB1 receptors and TRPV1 channels, Capasso, R., Orlando, P., Pagano, E., Aveta, T., Buono, L., Borrelli, F., Di Marzo, V., Izzo, A.A., 2014, 10.1111/bph.12759
  • Palmitoylethanolamide, a naturally occurring lipid, is an orally effective intestinal anti-inflammatory agent, Borrelli, F., Romano, B., Petrosino, S., Pagano, E., Capasso, R., Coppola, D., Battista, G., Orlando, P., Di Marzo, V., Izzo, A.A., 2014, 10.1111/bph.12907
  • Placebo effects in a multiple sclerosis spasticity enriched clinical trial with the oromucosal cannabinoid spray (THC/CBD): Dimension and possible causes, Di Marzo, V., Centonze, D., 2014, 10.1111/cns.12358
  • Preface, Di Marzo, V., Cannabinoids, 2014, 10.1002/9781118451281
  • Preface, Di Marzo, V., Wang, J.W., The Endocannabinoidome: The World of Endocannabinoids and Related Mediators, 2014, 10.1016/B978-0-12-420126-2.00016-X
  • Prostamide F2α receptor antagonism combined with inhibition of FAAH may block the pro-inflammatory mediators formed following selective FAAH inhibition, Ligresti, A., Martos, J., Wang, J., Guida, F., Allarà, M., Palmieri, V., Luongo, L., Woodward, D., Di Marzo, V., 2014, 10.1111/bph.12410
  • Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist, Brizzi, A., Aiello, F., Marini, P., Cascio, M.G., Corelli, F., Brizzi, V., De Petrocellis, L., Ligresti, A., Luongo, L., Lamponi, S., Maione, S., Pertwee, R.G., Di Marzo, V., 2014, 10.1016/j.bmc.2014.07.006
  • The A1 adenosine receptor as a new player in microglia physiology, Luongo, L., Guida, F., Imperatore, R., Napolitano, F., Gatta, L., Cristino, L., Giordano, C., Siniscalco, D., Di Marzo, V., Bellini, G., Petrelli, R., Cappellacci, L., Usiello, A., de Novellis, V., Rossi, F., Maione, S., 2014, 10.1002/glia.22592
  • The dual blocker of FAAH/TRPV1 N-arachidonoylserotonin reverses the behavioral despair induced by stress in rats and modulates the HPA-axis, Navarria, A., Tamburella, A., Iannotti, F.A., Micale, V., Camillieri, G., Gozzo, L., Verde, R., Imperatore, R., Leggio, G.M., Drago, F., Di Marzo, V., 2014, 10.1016/j.phrs.2014.04.014
  • The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels, Iannotti, F.A., Silvestri, C., Mazzarella, E., Martella, A., Calvigioni, D., Piscitelli, F., Ambrosino, P., Petrosino, S., Czifra, G., Bíŕo, T., Harkany, T., Taglialatela, M., Di Marzo, V., 2014, 10.1073/pnas.1406728111
  • The endocannabinoid system - Back to the scene of cardiometabolic risk factors control?, Martins, C.J.M., Genelhu, V., Di Marzo, V., Francischetti, E.A., 2014, 10.1055/s-0034-1375653
  • The endocannabinoid system mediates aerobic exercise-induced antinociception in rats, Galdino, G., Romero, T.R.L., Silva, J.F.P., Aguiar, D.C., De Paula, A.M., Cruz, J.S., Parrella, C., Piscitelli, F., Duarte, I.D., Di Marzo, V., Perez, A.C., 2014, 10.1016/j.neuropharm.2013.09.022
  • The Endocannabinoidome: The World of Endocannabinoids and Related Mediators, Di Marzo, V., Wang, J.W., The Endocannabinoidome: The World of Endocannabinoids and Related Mediators, 2014
  • 3-Ylidenephthalides as a new class of transient receptor potential channel TRPA1 and TRPM8 modulators, Ortar, G., Schiano Moriello, A., Morera, E., Nalli, M., Di Marzo, V., De Petrocellis, L., 2013, 10.1016/j.bmcl.2013.08.039
  • A novel fluorophosphonate inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol with potential anti-obesity effects, Bisogno, T., Mahadevan, A., Coccurello, R., Chang, J.W., Allarà, M., Chen, Y., Giacovazzo, G., Lichtman, A., Cravatt, B., Moles, A., Di Marzo, V., 2013, 10.1111/bph.12013
  • Acute inhibition of diacylglycerol lipase blocks endocannabinoid-mediated retrograde signalling: Evidence for on-demand biosynthesis of 2-arachidonoylglycerol, Hashimotodani, Y., Ohno-Shosaku, T., Tanimura, A., Kita, Y., Sano, Y., Shimizu, T., Di Marzo, V., Kano, M., 2013, 10.1113/jphysiol.2013.254474
  • Analogues of perillaketone as highly potent agonists of TRPA1 channel, Bassoli, A., Borgonovo, G., Morini, G., De Petrocellis, L., Schiano Moriello, A., Di Marzo, V., 2013, 10.1016/j.foodchem.2013.05.063
  • Analysis of the "endocannabinoidome" in peripheral tissues of obese Zucker rats, Iannotti, F.A., Piscitelli, F., Martella, A., Mazzarella, E., Allarà, M., Palmieri, V., Parrella, C., Capasso, R., Di Marzo, V., 2013, 10.1016/j.plefa.2013.06.002
  • Anandamide-derived prostamide F2α negatively regulates adipogenesis, Silvestri, C., Martella, A., Poloso, N.J., Piscitelli, F., Capasso, R., Izzo, A., Woodward, D.F., Di Marzo, V., 2013, 10.1074/jbc.M113.489906
  • Antiepileptic action of N-palmitoylethanolamine through CB1 and PPAR-α receptor activation in a genetic model of absence epilepsy, Citraro, R., Russo, E., Scicchitano, F., Van Rijn, C.M., Cosco, D., Avagliano, C., Russo, R., D'Agostino, G., Petrosino, S., Guida, F., Gatta, L., Van Luijtelaar, G., Maione, S., Di Marzo, V., Calignano, A., De Sarro, G., 2013, 10.1016/j.neuropharm.2012.11.017
  • Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease, Borrelli, F., Fasolino, I., Romano, B., Capasso, R., Maiello, F., Coppola, D., Orlando, P., Battista, G., Pagano, E., Di Marzo, V., Izzo, A.A., 2013, 10.1016/j.bcp.2013.01.017
  • Biaryl tetrazolyl ureas as inhibitors of endocannabinoid metabolism: Modulation at the N-portion and distal phenyl ring, Ortar, G., Morera, E., De Petrocellis, L., Ligresti, A., Schiano Moriello, A., Morera, L., Nalli, M., Ragno, R., Pirolli, A., Di Marzo, V., 2013, 10.1016/j.ejmech.2013.02.005
  • CB1 cannabinoid receptors couple to focal adhesion kinase to control insulin release, Malenczyk, K., Jazurek, M., Keimpema, E., Silvestri, C., Janikiewicz, J., Mackie, K., Di Marzo, V., Redowicz, M.J., Harkany, T., Dobrzyn, A., 2013, 10.1074/jbc.M113.478354
  • Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men, Berge, K., Piscitelli, F., Hoem, N., Silvestri, C., Meyer, I., Banni, S., Di Marzo, V., 2013, 10.1186/1476-511X-12-78
  • Control of experimental spasticity by targeting the degradation of endocannabinoids using selective fatty acid amide hydrolase inhibitors, Pryce, G., Cabranes, A., Fernández-Ruiz, J., Bisogno, T., Di Marzo, V., Long, J.Z., Cravatt, B.F., Giovannoni, G., Baker, D., 2013, 10.1177/1352458513485982
  • Different targets of anti-glucocorticoid treatment have been proposed, acting at supra-hypothalamic, HPA axis, glucocorticoid receptor and post-receptor levels., Di Marzo, V., 2013
  • Editorial, Di Marzo, V., 2013, 10.2174/1574889811308010001
  • Endocannabinoid system and mood disorders: Priming a target for new therapies, Micale, V., Di Marzo, V., Sulcova, A., Wotjak, C.T., Drago, F., 2013, 10.1016/j.pharmthera.2012.12.002
  • Endocannabinoids: A unique opportunity to develop multitarget analgesics, Maione, S., Costa, B., Di Marzo, V., 2013, 10.1016/j.pain.2013.03.023
  • Full Inhibition of Spinal FAAH Leads to TRPV1-Mediated Analgesic Effects in Neuropathic Rats and Possible Lipoxygenase-Mediated Remodeling of Anandamide Metabolism, Starowicz, K., Makuch, W., Korostynski, M., Malek, N., Slezak, M., Zychowska, M., Petrosino, S., De Petrocellis, L., Cristino, L., Przewlocka, B., Di Marzo, V., 2013, 10.1371/journal.pone.0060040
  • Impact of omega-6 polyunsaturated fatty acid supplementation and γ-aminobutyric acid on astrogliogenesis through the endocannabinoid system, Shinjyo, N., Piscitelli, F., Verde, R., Di Marzo, V., 2013, 10.1002/jnr.23231
  • Improvement in coronary circulatory function in morbidly obese individuals after gastric bypass-induced weight loss: Relation to alterations in endocannabinoids and adipocytokines, Quercioli, A., Montecucco, F., Pataky, Z., Thomas, A., Ambrosio, G., Staub, C., Di Marzo, V., Ratib, O., Mach, F., Golay, A., Schindler, T.H., 2013, 10.1093/eurheartj/eht085
  • Non-psychotropic analgesic drugs from the endocannabinoid system: "Magic bullet" or "multiple-target" strategies?, Starowicz, K., Di Marzo, V., 2013, 10.1016/j.ejphar.2013.01.075
  • Non-THC cannabinoids inhibit prostate carcinoma growth in vitro and in vivo: Pro-apoptotic effects and underlying mechanisms, De Petrocellis, L., Ligresti, A., Schiano Moriello, A., Iappelli, M., Verde, R., Stott, C.G., Cristino, L., Orlando, P., Di Marzo, V., 2013, 10.1111/j.1476-5381.2012.02027.x
  • Palmitoylethanolamide: Biochemistry, pharmacology and therapeutic use of a pleiotropic anti-inflammatory lipid mediator, Di Marzo, V., Skaper, S.D., 2013, 10.2174/1871527311312010004
  • PBOX-15 induces apoptosis and improves the efficacy of oxaliplatin in human colorectal cancer cell lines, Gangemi, G., Gazzerro, P., Fiore, D., Proto, M.C., Butini, S., Gemma, S., Casagni, A., Laezza, C., Vitale, M., Ligresti, A., Di Marzo, V., Zisterer, D.M., Nathwani, S., Williams, D.C., Campiani, G., Bifulco, M., 2013, 10.1016/j.ejphar.2013.07.011
  • Piperazinyl carbamate fatty acid amide hydrolase inhibitors and transient receptor potential channel modulators as "dual-target" analgesics, Maione, S., Costa, B., Piscitelli, F., Morera, E., De Chiaro, M., Comelli, F., Boccella, S., Guida, F., Verde, R., Ortar, G., Di Marzo, V., 2013, 10.1016/j.phrs.2013.07.003
  • Platelet-rich plasma exerts antinociceptive activity by a peripheral endocannabinoid-related mechanism, Descalzi, F., Ulivi, V., Cancedda, R., Piscitelli, F., Luongo, L., Guida, F., Gatta, L., Maione, S., Di Marzo, V., 2013, 10.1089/ten.tea.2012.0557
  • Possible involvement of endocannabinoids in the increase of morphine consumption in maternally deprived rat, Naudon, L., Piscitelli, F., Giros, B., Di Marzo, V., Daugé, V., 2013, 10.1016/j.neuropharm.2012.10.008
  • Preparation and characterization of Δ9- tetrahydrocannabinol-loaded biodegradable polymeric microparticles and their antitumoral efficacy on cancer cell lines, De La Ossa, D.H.P., Gil-Alegre, M.E., Ligresti, A., Aberturas, M.D.R., Molpeceres, J., Torres, A.I., Di Marzo, V., 2013, 10.3109/1061186X.2013.809089
  • Rimonabant precipitates anxiety in rats withdrawn from palatable food: Role of the central Amygdala, Blasio, A., Iemolo, A., Sabino, V., Petrosino, S., Steardo, L., Rice, K.C., Orlando, P., Iannotti, F.A., Di Marzo, V., Zorrilla, E.P., Cottone, P., 2013, 10.1038/npp.2013.153
  • Role of Endocannabinoids and Cannabinoid-1 Receptors in Cerebrocortical Blood Flow Regulation, Iring, A., Ruisanchez, É., Leszl-Ishiguro, M., Horváth, B., Benko, R., Lacza, Z., Járai, Z., Sándor, P., Di Marzo, V., Pacher, P., Benyó, Z., 2013, 10.1371/journal.pone.0053390
  • Some like it pungent and vile. TRPA1 as a molecular target for the malodorous vinyl disulfides from asafoetida, Shokoohinia, Y., Chianese, G., Appendino, G., Di Marzo, V., De Petrocellis, L., Ghannadi, A., Taghvayi, R., Fattahian, K., Soltani, R., Taglialatela-Scafati, O., 2013, 10.1016/j.fitote.2013.08.001
  • Synthesis and binding study of certain 6-arylalkanamides as molecular probes for cannabinoid receptor subtypes, Taher, A.T., Kadry, H.H., Allarà, M., Di Marzo, V., Abadi, A.H., Abouzid, K.A., 2013, 10.3109/14756366.2011.645241
  • Taste sensitivity to 6-n-propylthiouracil is associated with endocannabinoid plasma levels in normal-weight individuals, Tomassini Barbarossa, I., Carta, G., Murru, E., Melis, M., Zonza, A., Vacca, C., Muroni, P., Di Marzo, V., Banni, S., 2013, 10.1016/j.nut.2012.09.018
  • The administration of endocannabinoid uptake inhibitors OMDM-2 or VDM-11 promotes sleep and decreases extracellular levels of dopamine in rats, Murillo-Rodríguez, E., Palomero-Rivero, M., Millán-Aldaco, D., Di Marzo, V., 2013, 10.1016/j.physbeh.2012.11.007
  • The cannabinoid receptor type 2 as mediator of mesenchymal stromal cell immunosuppressive properties, Rossi, F., Bernardo, M.E., Bellini, G., Luongo, L., Conforti, A., Manzo, I., Guida, F., Cristino, L., Imperatore, R., Petrosino, S., Nobili, B., Di Marzo, V., Locatelli, F., Maione, S., 2013, 10.1371/journal.pone.0080022
  • The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis, Romano, B., Borrelli, F., Fasolino, I., Capasso, R., Piscitelli, F., Cascio, M.G., Pertwee, R.G., Coppola, D., Vassallo, L., Orlando, P., Di Marzo, V., Izzo, A.A., 2013, 10.1111/bph.12120
  • The cannabinoid Δ9-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity, Wargent, E.T., Zaibi, M.S., Silvestri, C., Hislop, D.C., Stocker, C.J., Stott, C.G., Guy, G.W., Duncan, M., Di Marzo, V., Cawthorne, M.A., 2013, 10.1038/nutd.2013.9
  • The effect of cannabichromene on adult neural stem/progenitor cells, Shinjyo, N., Di Marzo, V., 2013, 10.1016/j.neuint.2013.08.002
  • The endocannabinoid system in energy homeostasis and the etiopathology of metabolic disorders, Silvestri, C., Di Marzo, V., 2013, 10.1016/j.cmet.2013.03.001
  • The inhibition of 2-arachidonoyl-glycerol (2-AG) biosynthesis, rather than enhancing striatal damage, protects striatal neurons from malonate-induced death: A potential role of cyclooxygenase-2-dependent metabolism of 2-AG, Valdeolivas, S., Pazos, M.R., Bisogno, T., Piscitelli, F., Iannotti, F.A., Allarà, M., Sagredo, O., Di Marzo, V., Fernández-Ruiz, J., 2013, 10.1038/cddis.2013.387
  • "De-liver-ance" from CB 1: A way to counteract insulin resistance?, Di Marzo, V., 2012, 10.1053/j.gastro.2012.03.011
  • "Redundancy" of endocannabinoid inactivation: New challenges and opportunities for pain control, Piscitelli, F., Di Marzo, V., 2012, 10.1021/cn300015x
  • 2-Arylbenzofuran-based molecules as multipotent Alzheimer's disease modifying agents, Rizzo, S., Tarozzi, A., Bartolini, M., Da Costa, G., Bisi, A., Gobbi, S., Belluti, F., Ligresti, A., Allarà, M., Monti, J.-P., Andrisano, V., Di Marzo, V., Hrelia, P., Rampa, A., 2012, 10.1016/j.ejmech.2012.10.045
  • A re-evaluation of 9-HODE activity at TRPV1 channels in comparison with anandamide: Enantioselectivity and effects at other TRP channels and in sensory neurons, De Petrocellis, L., Schiano Moriello, A., Imperatore, R., Cristino, L., Starowicz, K., Di Marzo, V., 2012, 10.1111/j.1476-5381.2012.02122.x
  • At the heart of the matter: The endocannabinoid system in cardiovascular function and dysfunction, Montecucco, F., Di Marzo, V., 2012, 10.1016/j.tips.2012.03.002
  • Cannabinoid actions at TRPV channels: Effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation, de Petrocellis, L., Orlando, P., Moriello, A.S., Aviello, G., Stott, C., Izzo, A.A., di Marzo, V., 2012, 10.1111/j.1748-1716.2011.02338.x
  • Cannabinoid receptor type 1 and 2 expression in the skin of healthy dogs and dogs with atopic dermatitis, Campora, L., Miragliotta, V., Ricci, E., Cristino, L., di Marzo, V., Albanese, F., della Valle, M.F., Abramo, F., 2012, 10.2460/ajvr.73.7.988
  • Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer, Aviello, G., Romano, B., Borrelli, F., Capasso, R., Gallo, L., Piscitelli, F., Di Marzo, V., Izzo, A.A., 2012, 10.1007/s00109-011-0856-x
  • Chronic blockade of CB1 receptors reverses startle gating deficits and associated neurochemical alterations in rats reared in isolation, Zamberletti, E., Piscitelli, F., Cadeddu, F., Rubino, T., Fratta, W., Fadda, P., Di Marzo, V., Parolaro, D., 2012, 10.1111/j.1476-5381.2012.02095.x
  • Coronary vasomotor control in obesity and morbid obesity: Contrasting flow responses with endocannabinoids, leptin, and inflammation, Quercioli, A., Pataky, Z., Montecucco, F., Carballo, S., Thomas, A., Staub, C., Di Marzo, V., Vincenti, G., Ambrosio, G., Ratib, O., Golay, A., MacH, F., Harsch, E., Schindler, T.H., 2012, 10.1016/j.jcmg.2012.01.020
  • Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: Potent and selective CB2 cannabinoid receptor inverse agonists, Pasquini, S., Mugnaini, C., Ligresti, A., Tafi, A., Brogi, S., Falciani, C., Pedani, V., Pesco, N., Guida, F., Luongo, L., Varani, K., Borea, P.A., Maione, S., Di Marzo, V., Corelli, F., 2012, 10.1021/jm3003334
  • Discovery of prostamide F 2α and its role in inflammatory pain and dorsal horn nociceptive neuron hyperexcitability, Gatta, L., Piscitelli, F., Giordano, C., Boccella, S., Lichtman, A., Maione, S., Di Marzo, V., 2012, 10.1371/journal.pone.0031111
  • Effects of intra-ventrolateral periaqueductal grey palmitoylethanolamide on thermoceptive threshold and rostral ventromedial medulla cell activity, De Novellis, V., Luongo, L., Guida, F., Cristino, L., Palazzo, E., Russo, R., Marabese, I., D'Agostino, G., Calignano, A., Rossi, F., Di Marzo, V., Maione, S., 2012, 10.1016/j.ejphar.2011.11.034
  • Endocannabinoids in amygdala and nucleus accumbens mediate social play reward in adolescent rats, Trezza, V., Damsteegt, R., Manduca, A., Petrosino, S., van Kerkhof, L.W.M., Jeroen Pasterkamp, R., Zhou, Y., Campolongo, P., Cuomo, V., Di Marzo, V., Vanderschuren, L.J.M.J., 2012, 10.1523/JNEUROSCI.0114-12.2012
  • Endocannabinoids in nervous system health and disease: The big picture in a nutshell, Skaper, S.D., Di Marzo, V., 2012, 10.1098/rstb.2012.0313
  • Foreword, Di Marzo, V., 2012, 10.2174/157488912798842250
  • Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans: A pilot study, Monteleone, P., Piscitelli, F., Scognamiglio, P., Monteleone, A.M., Canestrelli, B., Di Marzo, V., Maj, M., 2012, 10.1210/jc.2011-3018
  • Indole-2-carboxamides as allosteric modulators of the cannabinoid CB 1 receptor, Piscitelli, F., Ligresti, A., La Regina, G., Coluccia, A., Morera, L., Allarà, M., Novellino, E., Di Marzo, V., Silvestri, R., 2012, 10.1021/jm201485c
  • Inhibitors of endocannabinoid breakdown for pain: Not so FA(AH)cile, after all, Di Marzo, V., 2012, 10.1016/j.pain.2012.06.016
  • Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice, Izzo, A.A., Capasso, R., Aviello, G., Borrelli, F., Romano, B., Piscitelli, F., Gallo, L., Capasso, F., Orlando, P., Di Marzo, V., 2012, 10.1111/j.1476-5381.2012.01879.x
  • Intense exercise increases circulating endocannabinoid and BDNF levels in humans-Possible implications for reward and depression, Heyman, E., Gamelin, F.-X., Goekint, M., Piscitelli, F., Roelands, B., Leclair, E., Di Marzo, V., Meeusen, R., 2012, 10.1016/j.psyneuen.2011.09.017
  • Investigations on the 4-quinolone-3-carboxylic acid motif. 6. Synthesis and pharmacological evaluation of 7-substituted quinolone-3-carboxamide derivatives as high affinity ligands for cannabinoid receptors, Pasquini, S., De Rosa, M., Ligresti, A., Mugnaini, C., Brizzi, A., Caradonna, N.P., Cascio, M.G., Bolognini, D., Pertwee, R.G., Di Marzo, V., Corelli, F., 2012, 10.1016/j.ejmech.2012.09.035
  • Kavalactones and the endocannabinoid system: The plant-derived yangonin is a novel CB 1 receptor ligand, Ligresti, A., Villano, R., Allarà, M., Ujváry, I., Di Marzo, V., 2012, 10.1016/j.phrs.2012.04.003
  • Leucettamols, bifunctionalized marine sphingoids, act as modulators of TRPA1 and TRPM8 channels, Chianese, G., Fattorusso, E., Putra, M.Y., Calcinai, B., Bavestrello, G., Schiano Moriello, A., De Petrocellis, L., Di Marzo, V., Taglialatela-Scafati, O., 2012, 10.3390/md10112435
  • Modulation of mouse gastrointestinal motility by allyl isothiocyanate, a constituent of cruciferous vegetables (Brassicaceae): Evidence for TRPA1-independent effects, Capasso, R., Aviello, G., Romano, B., Borrelli, F., De Petrocellis, L., Di Marzo, V., Izzo, A.A., 2012, 10.1111/j.1476-5381.2011.01703.x
  • Modulation of thermo-transient receptor potential (thermo-TRP) channels by thymol-based compounds, Ortar, G., Morera, L., Schiano Moriello, A., Morera, E., Nalli, M., Di Marzo, V., De Petrocellis, L., 2012, 10.1016/j.bmcl.2012.03.055
  • Neural precursor cells induce cell death of high-grade astrocytomas through stimulation of TRPV1, Stock, K., Kumar, J., Synowitz, M., Petrosino, S., Imperatore, R., Smith, E.S.J., Wend, P., Purfürst, B., Nuber, U.A., Gurok, U., Matyash, V., Wälzlein, J.-H., Chirasani, S.R., Dittmar, G., Cravatt, B.F., Momma, S., Lewin, G.R., Ligresti, A., De Petrocellis, L., Cristino, L., Di Marzo, V., Kettenmann, H., Glass, R., 2012, 10.1038/nm.2827
  • Novel bioactive metabolites of dipyrone (metamizol), Rogosch, T., Sinning, C., Podlewski, A., Watzer, B., Schlosburg, J., Lichtman, A.H., Cascio, M.G., Bisogno, T., Di Marzo, V., Nüsing, R., Imming, P., 2012, 10.1016/j.bmc.2011.11.028
  • Palvanil, a non-pungent capsaicin analogue, inhibits inflammatory and neuropathic pain with little effects on bronchopulmonary function and body temperature, Luongo, L., Costa, B., D'Agostino, B., Guida, F., Comelli, F., Gatta, L., Matteis, M., Sullo, N., De Petrocellis, L., De Novellis, V., Maione, S., Di Marzo, V., 2012, 10.1016/j.phrs.2012.05.005
  • Poly-ε-caprolactone microspheres as a drug delivery system for cannabinoid administration: Development, characterization and in vitro evaluation of their antitumoral efficacy, Hernan Perez De La Ossa, D., Ligresti, A., Gil-Alegre, M.E., Aberturas, M.R., Molpeceres, J., Di Marzo, V., Torres Suárez, A.I., 2012, 10.1016/j.jconrel.2012.05.003
  • Rational design, synthesis and anti-proliferative properties of new CB2 selective cannabinoid receptor ligands: An investigation of the 1,8-naphthyridin-2(1H)-one scaffold, Manera, C., Saccomanni, G., Malfitano, A.M., Bertini, S., Castelli, F., Laezza, C., Ligresti, A., Lucchesi, V., Tuccinardi, T., Rizzolio, F., Bifulco, M., Di Marzo, V., Giordano, A., MacChia, M., Martinelli, A., 2012, 10.1016/j.ejmech.2012.03.031
  • Second generation CB1 receptor blockers and other inhibitors of peripheral endocannabinoid overactivity and the rationale of their use against metabolic disorders, Silvestri, C., Di Marzo, V., 2012, 10.1517/13543784.2012.704019
  • Sesquiterpenoids from common ragweed (Ambrosia artemisiifolia L.), an invasive biological polluter, Taglialatela-Scafati, O., Pollastro, F., Minassi, A., Chianese, G., De Petrocellis, L., Di Marzo, V., Appendino, G., 2012, 10.1002/ejoc.201200650
  • Spinal anandamide produces analgesia in neuropathic rats: Possible CB 1- and TRPV1-mediated mechanisms, Starowicz, K., Makuch, W., Osikowicz, M., Piscitelli, F., Petrosino, S., Di Marzo, V., Przewlocka, B., 2012, 10.1016/j.neuropharm.2011.11.021
  • Synthesis and biological evaluation of [6]-gingerol analogues as transient receptor potential channel TRPV1 and TRPA1 modulators, Morera, E., De Petrocellis, L., Morera, L., Moriello, A.S., Nalli, M., Di Marzo, V., Ortar, G., 2012, 10.1016/j.bmcl.2011.12.113
  • The 'headache tree' via umbellulone and TRPA1 activates the trigeminovascular system, Nassini, R., Materazzi, S., Vriens, J., Prenen, J., Benemei, S., De Siena, G., La Marca, G., Andr, E., Preti, D., Avonto, C., Sadofsky, L., Di Marzo, V., De Petrocellis, L., Dussor, G., Porreca, F., Taglialatela-Scafati, O., Appendino, G., Nilius, B., Geppetti, P., 2012, 10.1093/brain/awr272
  • The activation of the cannabinoid receptor type 2 reduces neutrophilic protease-mediated vulnerability in atherosclerotic plaques, Montecucco, F., Di Marzo, V., Da Silva, R.F., Vuilleumier, N., Capettini, L., Lenglet, S., Pagano, S., Piscitelli, F., Quintao, S., Bertolotto, M., Pelli, G., Galan, K., Pilet, L., Kuzmanovic, K., Burger, F., Pane, B., Spinella, G., Braunersreuther, V., Gayet-Ageron, A., Pende, A., Viviani, G.L., Palombo, D., Dallegri, F., Roux-Lombard, P., Santos, R.A.S., Stergiopulos, N., Steffens, S., Mach, F., 2012, 10.1093/eurheartj/ehr449
  • The first dual ChE/FAAH inhibitors: New perspectives for Alzheimer's disease?, Rampa, A., Bartolini, M., Bisi, A., Belluti, F., Gobbi, S., Andrisano, V., Ligresti, A., Di Marzo, V., 2012, 10.1021/ml200313p
  • The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: Potential implications for the treatment of obesity, Heyman, E., Gamelin, F.-X., Aucouturier, J., Di Marzo, V., 2012, 10.1111/j.1467-789X.2012.01026.x
  • TRPV1-dependent and-independent alterations in the limbic cortex of neuropathic mice: Impact on glial caspases and pain perception, Giordano, C., Cristino, L., Luongo, L., Siniscalco, D., Petrosino, S., Piscitelli, F., Marabese, I., Gatta, L., Rossi, F., Imperatore, R., Palazzo, E., De Novellis, V., Di Marzo, V., Maione, S., 2012, 10.1093/cercor/bhr328
  • Why do cannabinoid receptors have more than one endogenous ligand?, Di Marzo, V., De Petrocellis, L., 2012, 10.1098/rstb.2011.0382
  • 1-Aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamide: An effective scaffold for the design of either CB 1 or CB 2 receptor ligands, Piscitelli, F., Ligresti, A., La Regina, G., Gatti, V., Brizzi, A., Pasquini, S., Allar, M., Carai, M.A.M., Novellino, E., Colombo, G., Di Marzo, V., Corelli, F., Silvestri, R., 2011, 10.1016/j.ejmech.2011.09.037
  • Alteration of the endocannabinoid system in mouse brain during prion disease, Petrosino, S., Ménard, B., Zsürger, N., Di Marzo, V., Chabry, J., 2011, 10.1016/j.neuroscience.2010.12.046
  • Altered endocannabinoid signalling after a high-fat diet in Apoe -/- mice: Relevance to adipose tissue inflammation, hepatic steatosis and insulin resistance, Bartelt, A., Orlando, P., Mele, C., Ligresti, A., Toedter, K., Scheja, L., Heeren, J., Di Marzo, V., 2011, 10.1007/s00125-011-2274-6
  • An NMR spectroscopic method to identify and classify thiol-trapping agents: Revival of michael acceptors for drug discovery?, Avonto, C., Taglialatela-Scafati, O., Pollastro, F., Minassi, A., Di-Marzo, V., De-Petrocellis, L., Appendino, G., 2011, 10.1002/anie.201005959
  • Anandamide-loaded nanoparticles: Preparation and characterization, Aberturas, M.R., Hernán, D., Gil, M.E., Ligresti, L.A., De Petrocellis, L., Torres, A.I., Di Marzo, V., Molpeceres, J., 2011, 10.3109/02652048.2010.546436
  • Bioactive prenylogous cannabinoid from fiber hemp (Cannabis sativa), Pollastro, F., Taglialatela-Scafati, O., Allarà, M., Muñoz, E., Di Marzo, V., De Petrocellis, L., Appendino, G., 2011, 10.1021/np200500p
  • Cannabinoid CB1 receptor antagonism prevents neurochemical and behavioural deficits induced by chronic phencyclidine, Guidali, C., Viganò, D., Petrosino, S., Zamberletti, E., Realini, N., Binelli, G., Rubino, T., Di Marzo, V., Parolaro, D., 2011, 10.1017/S1461145710000209
  • Cannabinoids and endocannabinoids in metabolic disorders with focus on diabetes, Di Marzo, V., Piscitelli, F., Mechoulam, R., 2011, 10.1007/978-3-642-17214-4-4
  • Cannabinomimetic lipid from a marine cyanobacterium, Gutiérrez, M., Pereira, A.R., Debonsi, H.M., Ligresti, A., Di Marzo, V., Gerwick, W.H., 2011, 10.1021/np200610t
  • Cell signalling: Why fasting worms age slowly, De Petrocellis, L., Di Marzo, V., 2011, 10.1038/473161a
  • Desulfohaplosamate, a new phosphate-containing steroid from Dasychalina sp., is a selective cannabinoid CB2 receptor ligand, Chianese, G., Fattorusso, E., Taglialatela-Scafati, O., Bavestrello, G., Calcinai, B., Dien, H.A., Ligresti, A., Di Marzo, V., 2011, 10.1016/j.steroids.2011.03.013
  • Effect of dietary krill oil supplementation on the endocannabinoidome of metabolically relevant tissues from high-fat-fed mice, Piscitelli, F., Carta, G., Bisogno, T., Murru, E., Cordeddu, L., Berge, K., Tandy, S., Cohn, J., Griinari, M., Banni, S., Di Marzo, V., 2011, 10.1186/1743-7075-8-51
  • Effect of the Cannabinoid Receptor-1 antagonist SR141716A on human adipocyte inflammatory profile and differentiation, Murumalla, R., Bencharif, K., Gence, L., Bhattacharya, A., Tallet, F., Gonthier, M.-P., Petrosino, S., Di Marzo, V., Cesari, M., Hoareau, L., Roche, R., 2011, 10.1186/1476-9255-8-33
  • Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes, De Petrocellis, L., Ligresti, A., Moriello, A.S., Allarà, M., Bisogno, T., Petrosino, S., Stott, C.G., Di Marzo, V., 2011, 10.1111/j.1476-5381.2010.01166.x
  • Effects of cannabinoids and cannabinoid-enriched Cannabis extracts on TRP channels and endocannabinoid metabolic enzymes, De Petrocellis, L., Ligresti, A., Moriello, A.S., Allarà, M., Bisogno, T., Petrosino, S., Stott, C.G., Di Marzo, V., 2011, 10.1111/bph.2011.163.issue-7
  • Elevated endocannabinoid plasma levels are associated with coronary circulatory dysfunction in obesity, Quercioli, A., Pataky, Z., Vincenti, G., Makoundou, V., Di Marzo, V., Montecucco, F., Carballo, S., Thomas, A., Staub, C., Steffens, S., Seimbille, Y., Golay, A., Ratib, O., Harsch, E., MacH, F., Schindler, T.H., 2011, 10.1093/eurheartj/ehr029
  • Endocannabinoid pathways and their role in multiple sclerosis-related muscular dysfunction, Di Marzo, V., 2011, 10.1586/ern.11.26
  • Endocannabinoid signaling in the brain: Biosynthetic mechanisms in the limelight, Di Marzo, V., 2011, 10.1038/nn.2720
  • Endocannabinoids generated by Ca2+ or by metabotropic glutamate receptors appear to arise from different pools of diacylglycerol lipase, Zhang, L., Wang, M., Bisogno, T., di Marzo, V., Alger, B.E., 2011, 10.1371/journal.pone.0016305
  • Endocannabinoids: An appetite for fat, Di Marzo, V., 2011, 10.1073/pnas.1109567108
  • Gut feelings about the endocannabinoid system, Di Marzo, V., Piscitelli, F., 2011, 10.1111/j.1365-2982.2011.01689.x
  • Homology modeling in tandem with 3D-QSAR analyses: A computational approach to depict the agonist binding site of the human CB2 receptor, Cichero, E., Ligresti, A., Allar, M., Di Marzo, V., Lazzati, Z., D'Ursi, P., Marabotti, A., Milanesi, L., Spallarossa, A., Ranise, A., Fossa, P., 2011, 10.1016/j.ejmech.2011.07.023
  • Inhibition of basal and ultraviolet B-induced melanogenesis by cannabinoid CB1 receptors: A keratinocyte-dependent effect, Magina, S., Esteves-Pinto, C., Moura, E., Serrão, M.P., Moura, D., Petrosino, S., Di Marzo, V., Vieira-Coelho, M.A., 2011, 10.1007/s00403-011-1126-z
  • Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice, Pasquini, S., De Rosa, M., Pedani, V., Mugnaini, C., Guida, F., Luongo, L., De Chiaro, M., Maione, S., Dragoni, S., Frosini, M., Ligresti, A., Di Marzo, V., Corelli, F., 2011, 10.1021/jm200476p
  • Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects, Banni, S., Carta, G., Murru, E., Cordeddu, L., Giordano, E., Sirigu, A.R., Berge, K., Vik, H., Maki, K.C., Di Marzo, V., Griinari, M., 2011, 10.1186/1743-7075-8-7
  • Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats, Deblon, N., Veyrat-Durebex, C., Bourgoin, L., Caillon, A., Bussier, A.-L., Petrosino, S., Piscitelli, F., Legros, J.-J., Geenen, V., Foti, M., Wahli, W., Di Marzo, V., Rohner-Jeanrenaud, F., 2011, 10.1371/journal.pone.0025565
  • N-palmitoyl-vanillamide (palvanil) is a non-pungent analogue of capsaicin with stronger desensitizing capability against the TRPV1 receptor and anti-hyperalgesic activity, De Petrocellis, L., Guida, F., Moriello, A.S., De Chiaro, M., Piscitelli, F., De Novellis, V., Maione, S., Di Marzo, V., 2011, 10.1016/j.phrs.2010.12.019
  • Non-psychoactive cannabinoids modulate the descending pathway of antinociception in anaesthetized rats through several mechanisms of action, Maione, S., Piscitelli, F., Gatta, L., Vita, D., De Petrocellis, L., Palazzo, E., De Novellis, V., Di Marzo, V., 2011, 10.1111/j.1476-5381.2010.01063.x
  • Palmitoylethanolamide counteracts reactive astrogliosis induced by β-amyloid peptide, Scuderi, C., Esposito, G., Blasio, A., Valenza, M., Arietti, P., Steardo Jr., L., Carnuccio, R., De Filippis, D., Petrosino, S., Iuvone, T., Di Marzo, V., Steardo, L., 2011, 10.1111/j.1582-4934.2011.01267.x
  • Peripheral effects of the endocannabinoid system in energy homeostasis: Adipose tissue, liver and skeletal muscle, Silvestri, C., Ligresti, A., Di Marzo, V., 2011, 10.1007/s11154-011-9167-3
  • Protective role of cannabinoid receptor type 2 in a mouse model of diabetic nephropathy, Barutta, F., Piscitelli, F., Pinach, S., Bruno, G., Gambino, R., Rastaldi, M.P., Salvidio, G., Di Marzo, V., Perin, P.C., Gruden, G., 2011, 10.2337/db10-1809
  • Questions and answers, Haas, J., Di Marzo, V., Vermersch, P., 2011, 10.1586/ern.11.28
  • Resorcinol-sn-glycerol derivatives: Novel 2-Arachidonoylglycerol mimetics endowed with high affinity and selectivity for cannabinoid type 1 receptor, Brizzi, A., Cascio, M.G., Frosini, M., Ligresti, A., Aiello, F., Biotti, I., Brizzi, V., Pertwee, R.G., Corelli, F., Di Marzo, V., 2011, 10.1021/jm200529h
  • The blockade of the transient receptor potential vanilloid type 1 and fatty acid amide hydrolase decreases symptoms and central sequelae in the medial prefrontal cortex of neuropathic rats, de Novellis, V., Vita, D., Gatta, L., Luongo, L., Bellini, G., De Chiaro, M., Marabese, I., Siniscalco, D., Boccella, S., Piscitelli, F., Di Marzo, V., Palazzo, E., Rossi, F., Maione, S., 2011, 10.1186/1744-8069-7-7
  • The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy, Rossi, F., Bellini, G., Luongo, L., Torella, M., Mancusi, S., De Petrocellis, L., Petrosino, S., Siniscalco, D., Orlando, P., Scafuro, M., Colacurci, N., Perrotta, S., Nobili, B., Di Marzo, V., Maione, S., 2011, 10.1016/j.bone.2011.01.001
  • Three-dimensional quantitative structure-selectivity relationships analysis guided rational design of a highly selective ligand for the cannabinoid receptor 2, Brogi, S., Corelli, F., Di Marzo, V., Ligresti, A., Mugnaini, C., Pasquini, S., Tafi, A., 2011, 10.1016/j.ejmech.2010.11.034
  • Use of palmitoylethanolamide in the entrapment neuropathy of the median in the wrist, Conigliaro, R., Drago, V., Foster, P.S., Schievano, C., Di Marzo, V., 2011
  • A gradient of 2-arachidonoylglycerol regulates mouse epididymal sperm cell start-up., Cobellis, G., Ricci, G., Cacciola, G., Orlando, P., Petrosino, S., Cascio, M.G., Bisogno, T., De Petrocellis, L., Chioccarelli, T., Altucci, L., Fasano, S., Meccariello, R., Pierantoni, R., Ledent, C., Di Marzo, V., 2010, 10.1095/biolreprod.109.079210
  • An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis, Loría, F., Petrosino, S., Hernangómez, M., Mestre, L., Spagnolo, A., Correa, F., Di Marzo, V., Docagne, F., Guaza, C., 2010, 10.1016/j.nbd.2009.09.020
  • Anandamide and AM251, via water, modulate food intake at central and peripheral level in fish, Piccinetti, C.C., Migliarini, B., Petrosino, S., Di Marzo, V., Carnevali, O., 2010, 10.1016/j.ygcen.2009.09.017
  • Anandamide enhances IL-10 production in activated microglia by targeting CB2 receptors: Roles of ERK1/2, JNK, and NF-κB, Correa, F., Hernangómez, M., Mestre, L., Loría, F., Spagnolo, A., Docagne, F., Di Marzo, V., Guaza, C., 2010, 10.1002/glia.20907
  • Basal and fasting/refeeding-regulated tissue levels of endogenous PPAR-α ligands in zucker rats, Izzo, A.A., Piscitelli, F., Capasso, R., Marini, P., Cristino, L., Petrosino, S., Di Marzo, V., 2010, 10.1038/oby.2009.186
  • Cannabimovone, a cannabinoid with a rearranged terpenoid skeleton from hemp, Taglialatela-Scafati, O., Pagani, A., Scala, F., De Petrocellis, L., Di Marzo, V., Grassi, G., Appendino, G., 2010, 10.1002/ejoc.200901464
  • Cannabinoid CB1 receptor expression in relation to visceral adipose depots, endocannabinoid levels, microvascular damage, and the presence of the Cnr1 A3813G variant in humans, Bordicchia, M., Battistoni, I., Mancinelli, L., Giannini, E., Refi, G., Minardi, D., Muzzonigro, G., Mazzucchelli, R., Montironi, R., Piscitelli, F., Petrosino, S., Dessì-Fulgheri, P., Rappelli, A., Di Marzo, V., Sarzani, R., 2010, 10.1016/j.metabol.2009.09.018
  • Cannabinoid receptors and endocannabinoids: Role in neuroinflammatory and neurodegenerative disorders, Bisogno, T., Di Marzo, V., 2010
  • Chemical characterisation of oxidative degradation products of Δ9-THC, Carbone, M., Castelluccio, F., Daniele, A., Sutton, A., Ligresti, A., Di Marzo, V., Gavagnin, M., 2010, 10.1016/j.tet.2010.10.025
  • Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis, Caraceni, P., Viola, A., Piscitelli, F., Giannone, F., Berzigotti, A., Cescon, M., Domenicali, M., Petrosino, S., Giampalma, E., Riili, A., Grazi, G., Golfieri, R., Zoli, M., Bernardi, M., Di Marzo, V., 2010, 10.1111/j.1478-3231.2009.02137.x
  • DAG lipase involvement in depolarization-induced suppression of inhibition: Does endocannabinoid biosynthesis always meet the demand?, Min, R., Di Marzo, V., Mansvelder, H.D., 2010, 10.1177/1073858410373281
  • Diacylglycerol lipase is not involved in depolarization-induced suppression of inhibition at unitary inhibitory connections in mouse hippocampus, Min, R., Testa-Silva, G., Heistek, T.S., Canto, C.B., Lodder, J.C., Bisogno, T., Di Marzo, V., Brussaard, A.B., Burnashev, N., Mansvelder, H.D., 2010, 10.1523/JNEUROSCI.BC-3622-09.2010
  • Dietary krill oil increases docosahexaenoic acid and reduces 2-arachidonoylglycerol but not N-acylethanolamine levels in the brain of obese Zucker rats, Di Marzo, V., Griinari, M., Carta, G., Murru, E., Ligresti, A., Cordeddu, L., Giordano, E., Bisogno, T., Collu, M., Batetta, B., Uda, S., Berge, K., Banni, S., 2010, 10.1016/j.idairyj.2009.11.015
  • Differential alterations of the concentrations of endocannabinoids and related lipids in the subcutaneous adipose tissue of obese diabetic patients, Annuzzi, G., Piscitelli, F., Di Marino, L., Patti, L., Giacco, R., Costabile, G., Bozzetto, L., Riccardi, G., Verde, R., Petrosino, S., Rivellese, A.A., Di Marzo, V., 2010, 10.1186/1476-511X-9-43
  • Effect of dietary fat on endocannabinoids and related mediators: Consequences on energy homeostasis, inflammation and mood, Banni, S., di Marzo, V., 2010, 10.1002/mnfr.200900516
  • Enantioselective synthesis of 3(S)-hydroxy polygodial derivatives and evaluation of their vanilloid activity, D'Acunto, M., Della Monica, C., Izzo, I., De Petrocellis, L., Di Marzo, V., Spinella, A., 2010, 10.1016/j.tet.2010.11.002
  • Endocannabinoid modulation in the olfactory epithelium, Breunig, E., Czesnik, D., Piscitelli, F., Di Marzo, V., Manzini, I., Schild, D., 2010, 10.1007/978-3-642-14426-4_11
  • Endocannabinoids as regulators of transient receptor potential (TRP) channels: A further opportunity to develop new endocannabinoid-based therapeutic drugs, Di Marzo, V., De Petrocellis, L., 2010, 10.2174/092986710790980078
  • Enhanced cognitive performance of dopamine D3 receptor " knock-out" mice in the step-through passive-avoidance test: Assessing the role of the endocannabinoid/endovanilloid systems, Micale, V., Cristino, L., Tamburella, A., Petrosino, S., Leggio, G.M., Di Marzo, V., Drago, F., 2010, 10.1016/j.phrs.2010.02.003
  • Exploiting Nanotechnologies and TRPV1 Channels to Investigate the Putative Anandamide Membrane Transporter, Ligresti, A., de Petrocellis, L., de la Ossa, D.H.P., Aberturas, R., Cristino, L., Moriello, A.S., Finizio, A., Gil, M.E., Torres, A.-I., Molpeceres, J., di Marzo, V., 2010, 10.1371/journal.pone.0010239
  • FAAH and MAGL inhibitors: Therapeutic opportunities from regulating endocannabinoid levels, Petrosino, S., Di Marzo, V., 2010
  • In vitro and in vivo pharmacological characterization of two novel selective cannabinoid CB2 receptor inverse agonists, Cascio, M.G., Bolognini, D., Pertwee, R.G., Palazzo, E., Corelli, F., Pasquini, S., Di Marzo, V., Maione, S., 2010, 10.1016/j.phrs.2009.11.011
  • International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: Beyond CB1 and CB2, Pertwee, R.G., Howlett, A.C., Abood, M.E., Alexander, S.P.H., Di Marzo, V., Elphick, M.R., Greasley, P.J., Hansen, H.S., Kunos, G., Mackie, K., Mechoulam, R., Ross, R.A., 2010, 10.1124/pr.110.003004
  • Investigations on the 4-Quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands, Pasquini, S., Ligresti, A., Mugnaini, C., Semeraro, T., Cicione, L., De Rosa, M., Guida, F., Luongo, L., De Chiaro, M., Cascio, M.G., Bolognini, D., Marini, P., Pertwee, R., Maione, S., Di Marzo, V., Corelli, F., 2010, 10.1021/jm100123x
  • Levels of endocannabinoids and palmitoylethanolamide and their pharmacological manipulation in chronic granulomatous inflammation in rats, De Filippis, D., D'Amico, A., Cipriano, M., Petrosino, S., Orlando, P., Di Marzo, V., Iuvone, T., 2010, 10.1016/j.phrs.2009.11.005
  • Maternal dietary fat determines metabolic profile and the magnitude of endocannabinoid inhibition of the stress response in neonatal rat offspring, D'Asti, E., Long, H., Tremblay-Mercier, J., Grajzer, M., Cunnane, S.C., Di Marzo, V., Walker, C.-D., 2010, 10.1210/en.2009-1092
  • N-palmitoyl-ethanolamine: Biochemistry and new therapeutic opportunities, Petrosino, S., Iuvone, T., Di Marzo, V., 2010, 10.1016/j.biochi.2010.01.006
  • Non-CB1, Non-CB2 receptors for endocannabinoids, plant cannabinoids, and synthetic cannabimimetics: Focus on G-protein-coupled receptors and transient receptor potential channels, De Petrocellis, L., Di Marzo, V., 2010, 10.1007/s11481-009-9177-z
  • Novel mechanisms in obesity, type 2 diabetes and accompanying inflammation: Focus on lipid signaling, Di Marzo, V., 2010, 10.1016/j.ddmec.2011.01.001
  • Phytocannabinoids beyond the Cannabis plant - Do they exist?, Gertsch, J., Pertwee, R.G., Di Marzo, V., 2010, 10.1111/j.1476-5381.2010.00745.x
  • Possible Anandamide and Palmitoylethanolamide involvement in human stroke, Naccarato, M., Pizzuti, D., Petrosino, S., Simonetto, M., Ferigo, L., Chiodo Grandi, F., Pizzolato, G., Di Marzo, V., 2010, 10.1186/1476-511X-9-47
  • Protective role of palmitoylethanolamide in contact allergic dermatitis, Petrosino, S., Cristino, L., Karsak, M., Gaffal, E., Ueda, N., Tüting, T., Bisogno, T., De Filippis, D., D'Amico, A., Saturnino, C., Orlando, P., Zimmer, A., Iuvone, T., Di Marzo, V., 2010, 10.1111/j.1398-9995.2009.02254.x
  • Synthesis and biological evaluation of new N-alkyl 1-aryl-5-(1H-pyrrol-1- yl)-1H-pyrazole-3-carboxamides as cannabinoid receptor ligands, Silvestri, R., Ligresti, A., La Regina, G., Piscitelli, F., Gatti, V., Lavecchia, A., Brizzi, A., Pasquini, S., Allar, M., Fantini, N., Carai, M.A.M., Bigogno, C., Rozio, M.G., Sinisi, R., Novellino, E., Colombo, G., Di Marzo, V., Dondio, G., Corelli, F., 2010, 10.1016/j.ejmech.2010.09.053
  • The dual fatty acid amide hydrolase/TRPV1 blocker, N-arachidonoyl-serotonin, relieves carrageenan-induced inflammation and hyperalgesia in mice, Costa, B., Bettoni, I., Petrosino, S., Comelli, F., Giagnoni, G., Di Marzo, V., 2010, 10.1016/j.phrs.2010.02.001
  • The endocannabinoid 2-arachidonoyl-glycerol controls odor sensitivity in larvae of Xenopus laevis, Breunig, E., Manzini, I., Piscitelli, F., Gutermann, B., Di Marzo, V., Schild, D., Czesnik, D., 2010, 10.1523/JNEUROSCI.4030-09.2010
  • The levels of the endocannabinoid receptor CB2 and its ligand 2-arachidonoylglycerol are elevated in endometrial carcinoma, Guida, M., Ligresti, A., De Filippis, D., D'Amico, A., Petrosino, S., Cipriano, M., Bifulco, G., Simonetti, S., Orlando, P., Insabato, L., Nappi, C., Sardo, A.D.S., Di Marzo, V., Iuvone, T., 2010, 10.1210/en.2009-0883
  • The plant cannabinoid Δ 9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice, Bolognini, D., Costa, B., Maione, S., Comelli, F., Marini, P., Di Marzo, V., Parolaro, D., Ross, R.A., Gauson, L.A., Cascio, M.G., Pertwee, R.G., 2010, 10.1111/j.1476-5381.2010.00756.x
  • TRPV1 in Neuropathic Pain and Neurological and Neuropsychiatric Disorders, Palazzo, E., Starowicz, K., Maione, S., Di Marzo, V., 2010, 10.1002/9780470588284.ch10
  • Adelmidrol, a palmitoylethanolamide analogue, reduces chronic inflammation in a carrageenin-granuloma model in rats, De Filippis, D., D'Amico, A., Cinelli, M.P., Esposito, G., Di Marzo, V., Iuvone, T., 2009, 10.1111/j.1582-4934.2008.00353.x
  • Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems, Micale, V., Cristino, L., Tamburella, A., Petrosino, S., Leggio, G.M., Drago, F., Di Marzo, V., 2009, 10.1016/j.nbd.2009.06.015
  • An introduction to the endocannabinoid system: from the early to the latest concepts, De Petrocellis, L., Di Marzo, V., 2009, 10.1016/j.beem.2008.10.013
  • Anti-inflammatory effect of palmitoylethanolamide on human adipocytes, Hoareau, L., Buyse, M., Festy, F., Ravanan, P., Gonthier, M.-P., Matias, I., Petrosino, S., Tallet, F., D'Hellencourt, C.L., Cesari, M., Di Marzo, V., Roche, R., 2009, 10.1038/oby.2008.591
  • Anxiolytic effects in mice of a dual blocker of fatty acid amide hydrolase and transient receptor potential vanilloid type-1 channels, Micale, V., Cristino, L., Tamburella, A., Petrosino, S., Leggio, G.M., Drago, F., Di Marzo, V., 2009, 10.1038/npp.2008.98
  • Cannabidiol, a safe and non-psychotropic ingredient of the marijuana plant Cannabis sativa, is protective in a murine model of colitis, Borrelli, F., Aviello, G., Romano, B., Orlando, P., Capasso, R., Maiello, F., Guadagno, F., Petrosino, S., Capasso, F., Di Marzo, V., Izzo, A.A., 2009, 10.1007/s00109-009-0512-x
  • Cannabinoid CB1 receptor elevation of intracellular calcium in neuroblastoma SH-SY5Y cells: Interactions with muscarinic and δ-opioid receptors, Marini, P., Moriello, A.S., Cristino, L., Palmery, M., De Petrocellis, L., Di Marzo, V., 2009, 10.1016/j.bbamcr.2009.05.002
  • CB1 antagonists for obesitywhat lessons have we learned from rimonabant?, Di Marzo, V., Després, J.-P., 2009, 10.1038/nrendo.2009.197
  • Changes in plasma endocannabinoid levels in viscerally obese men following a 1 year lifestyle modification programme and waist circumference reduction: Associations with changes in metabolic risk factors, Di Marzo, V., Côté, M., Matias, I., Lemieux, I., Arsenault, B.J., Cartier, A., Piscitelli, F., Petrosino, S., Alméras, N., Després, J.-P., 2009, 10.1007/s00125-008-1178-6
  • Chemical synthesis, pharmacological characterization, and possible formation in unicellular fungi of 3-hydroxy-anandamide, De Petrocellis, L., Deva, R., Mainieri, F., Schaefer, M., Bisogno, T., Ciccoli, R., Ligresti, A., Hill, K., Nigam, S., Appendino, G., Di Marzo, V., 2009, 10.1194/jlr.M800337-JLR200
  • Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes, Appendino, G., Ligresti, A., Minassi, A., Cascio, M.G., Allarà, M., Taglialatela-Scafati, O., Pertwee, R.G., De Petrocellis, L., Di Marzo, V., 2009, 10.1021/jm900130m
  • Development of a potent inhibitor of 2-arachidonoylglycerol hydrolysis with antinociceptive activity in vivo, Bisogno, T., Ortar, G., Petrosino, S., Morera, E., Palazzo, E., Nalli, M., Maione, S., Di Marzo, V., 2009, 10.1016/j.bbalip.2008.10.007
  • Endocannabinoid chemical biology: a tool for the development of novel therapies, Petrosino, S., Ligresti, A., Di Marzo, V., 2009, 10.1016/j.cbpa.2009.04.616
  • Endocannabinoids may mediate the ability of (n-3) fatty acids to reduce ectopic fat and inflammatory mediators in obese Zucker rats, Batetta, B., Griinari, M., Carta, G., Murru, E., Ligresti, A., Cordeddu, L., Giordano, E., Sanna, F., Bisogno, T., Uda, S., Collu, M., Bruheim, I., Di Marzo, V., Banni, S., 2009, 10.3945/jn.109.104844
  • From endocannabinoid profiling to 'endocannabinoid therapeutics', Ligresti, A., Petrosino, S., Di Marzo, V., 2009, 10.1016/j.cbpa.2009.04.615
  • Functional interaction between TRPV1 and μ-opioid receptors in the descending antinociceptive pathway activates glutamate transmission and induces analgesia, Maione, S., Starowicz, K., Cristino, L., Guida, F., Palazzo, E., Luongo, L., Rossi, F., Marabese, I., De Novellis, V., Di Marzo, V., 2009, 10.1152/jn.91225.2008
  • Involvement of the endocannabinoid system in phencyclidine-induced cognitive deficits modelling schizophrenia, Vigano, D., Guidali, C., Petrosino, S., Realini, N., Rubino, T., Di Marzo, V., Parolaro, D., 2009, 10.1017/S1461145708009371
  • Lipidomic methodologies applicable to the study of endocannabinoids and related compounds: Endocannabinoidomics, Bisogno, T., Piscitelli, F., Di Marzo, V., 2009, 10.1002/ejlt.200800233
  • New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo, Brizzi, A., Brizzi, V., Cascio, M.G., Corelli, F., Guida, F., Ligresti, A., Maione, S., Martinelli, A., Pasquini, S., Tuccinardi, T., Di Marzo, V., 2009, 10.1021/jm8016255
  • Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb, Izzo, A.A., Borrelli, F., Capasso, R., Di Marzo, V., Mechoulam, R., 2009, 10.1016/j.tips.2009.07.006
  • Peripheral endocannabinoid dysregulation in obesity: Relation to intestinal motility and energy processing induced by food deprivation and re-feeding, Izzo, A.A., Piscitelli, F., Capasso, R., Aviello, G., Romano, B., Borrelli, F., Petrosino, S., Di Marzo, V., 2009, 10.1111/j.1476-5381.2009.00183.x
  • Rapid combinatorial access to a library of 1,5-disubstituted-3-indole-N- alkylacetamides as CB2 receptor ligands, Pasquini, S., Mugnaini, C., Brizzi, A., Ligresti, A., Di Marzo, V., Ghiron, C., Corelli, F., 2009, 10.1021/cc9000955
  • Rational design, synthesis, and pharmacological properties of new 1,8-naphthyridin-2(1H)-on-3-carboxamide derivatives as highly selective cannabinoid-2 receptor agonists, Manera, C., Saccomanni, G., Adinolfi, B., Benetti, V., Ligresti, A., Cascio, M.G., Tuccinardi, T., Lucchesi, V., Martinelli, A., Nieri, P., Masini, E., Di Marzo, V., Ferrarini, P.L., 2009, 10.1021/jm801563d
  • Regulation and possible role of endocannabinoids and related mediators in hypercholesterolemic mice with atherosclerosis, Montecucco, F., Matias, I., Lenglet, S., Petrosino, S., Burger, F., Pelli, G., Braunersreuther, V., Mach, F., Steffens, S., Di Marzo, V., 2009, 10.1016/j.atherosclerosis.2008.12.040
  • Role of endocannabinoids and endovanilloids in Ca2+ signalling, De Petrocellis, L., Di Marzo, V., 2009, 10.1016/j.ceca.2009.03.003
  • Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects, Di Marzo, V., Verrijken, A., Hakkarainen, A., Petrosino, S., Mertens, I., Lundbom, N., Piscitelli, F., Westerbacka, J., Soro-Paavonen, A., Matias, I., Van Gaal, L., Taskinen, M.-R., 2009, 10.1530/EJE-09-0643
  • Synthesis and biological evaluation of piperazinyl carbamates and ureas as fatty acid amide hydrolase (FAAH) and transient receptor potential (TRP) channel dual ligands, Morera, E., De Petrocellis, L., Morera, L., Moriello, A.S., Ligresti, A., Nalli, M., Woodward, D.F., Di Marzo, V., Ortar, G., 2009, 10.1016/j.bmcl.2009.09.033
  • Synthesis and pharmacological activity of a potent inhibitor of the biosynthesis of the endocannabinoid 2-arachidonoylglycerol, Bisogno, T., Burston, J.J., Rai, R., Allarà, M., Saha, B., Mahadevan, A., Razdan, R.K., Wiley, J.L., Di Marzo, V., 2009, 10.1002/cmdc.200800442
  • The biosynthesis of N-arachidonoyl dopamine (NADA), a putative endocannabinoid and endovanilloid, via conjugation of arachidonic acid with dopamine, Hu, S.S.-J., Bradshaw, H.B., Benton, V.M., Chen, J.S.-C., Huang, S.M., Minassi, A., Bisogno, T., Masuda, K., Tan, B., Roskoski Jr., R., Cravatt, B.F., Di Marzo, V., Walker, J.M., 2009, 10.1016/j.plefa.2009.05.026
  • The endocannabinoid system and pivotal role of the CB2 receptor in mouse spermatogenesis, Grimaldi, P., Orlando, P., Di Siena, S., Lolicato, F., Petrosino, S., Bisogno, T., Geremia, R., De Petrocellis, L., Di Marzo, V., 2009, 10.1073/pnas.0812789106
  • The endocannabinoid system as a link between homoeostatic and hedonic pathways involved in energy balance regulation, Di Marzo, V., Ligresti, A., Cristino, L., 2009, 10.1038/ijo.2009.67
  • The endocannabinoid system in metabolic control: a preface, Di Marzo, V., 2009, 10.1016/j.beem.2008.12.005
  • The endocannabinoid system is modulated in response to spinal cord injury in rats, Garcia-Ovejero, D., Arevalo-Martin, A., Petrosino, S., Docagne, F., Hagen, C., Bisogno, T., Watanabe, M., Guaza, C., Di Marzo, V., Molina-Holgado, E., 2009, 10.1016/j.nbd.2008.09.015
  • The endocannabinoid system: Its general strategy of action, tools for its pharmacological manipulation and potential therapeutic exploitation, Di Marzo, V., 2009, 10.1016/j.phrs.2009.02.010
  • The endovanilloid/endocannabinoid system in human osteoclasts: Possible involvement in bone formation and resorption, Rossi, F., Siniscalco, D., Luongo, L., De Petrocellis, L., Bellini, G., Petrosino, S., Torella, M., Santoro, C., Nobili, B., Perrotta, S., Di Marzo, V., Maione, S., 2009, 10.1016/j.bone.2008.10.056
  • TRPV1 channels control synaptic plasticity in the developing superior colliculus, Maione, S., Cristino, L., Migliozzi, A.L., Georgiou, A.L., Starowicz, K., Salt, T.E., Di Marzo, V., 2009, 10.1113/jphysiol.2009.171900
  • Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: Cannabinoid and non-cannabinoid receptor-mediated mechanisms, Maione, S., Morera, E., Marabese, I., Ligresti, A., Luongo, L., Ortar, G., Di Marzo, V., 2008, 10.1038/bjp.2008.308
  • Brain TRPV1: a depressing TR(i)P down memory lane?, Di Marzo, V., Gobbi, G., Szallasi, A., 2008, 10.1016/j.tips.2008.09.004
  • Carbamoyl tetrazoles as inhibitors of endocannabinoid inactivation: A critical revisitation, Ortar, G., Cascio, M.G., Moriello, A.S., Camalli, M., Morera, E., Nalli, M., Di Marzo, V., 2008, 10.1016/j.ejmech.2007.02.023
  • CB1 receptor antagonism: biological basis for metabolic effects, Di Marzo, V., 2008, 10.1016/j.drudis.2008.09.001
  • Dopamides, vanillylamides, ethanolamides, and arachidonic acid amides of anti-inflammatory and analgesic drug substances as TRPV1 ligands, Sinning, C., Watzer, B., De Petrocellis, L., Di Marzo, V., Imming, P., 2008, 10.1002/cmdc.200800271
  • Dysregulation of peripheral endocannabinoid levels in hyperglycemia and obesity: Effect of high fat diets, Matias, I., Petrosino, S., Racioppi, A., Capasso, R., Izzo, A.A., Di Marzo, V., 2008, 10.1016/j.mce.2008.01.026
  • Editorial: New potential therapies from vanilloid transient receptor cation (TRPV) channels, Di Marzo, V., Starowicz, K., 2008, 10.2174/138161208783330736
  • Effect of polyunsaturated fatty acids on endocannabinoid and N-acyl-ethanolamine levels in mouse adipocytes, Matias, I., Carta, G., Murru, E., Petrosino, S., Banni, S., Di Marzo, V., 2008, 10.1016/j.bbalip.2007.11.001
  • Endocannabinoid dysregulation in the pancreas and adipose tissue of mice fed with a high-fat diet, Starowicz, K.M., Cristino, L., Matias, I., Capasso, R., Racioppi, A., Izzo, A.A., Di Marzo, V., 2008, 10.1038/oby.2007.106
  • Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning, Mulder, J., Aguado, T., Keimpema, E., Barabás, K., Rosado, C.J.B., Nguyen, L., Menory, K., Marsicano, G., Di Marzo, V., Hurd, Y.L., Guillemot, F., Mackie, K., Lutz, B., Guzmán, M., Lu, H.-C., Galve-Roperh, I., Harkany, T., 2008, 10.1073/pnas.0803545105
  • Endocannabinoids in energy homeostasis and metabolic disorders, Matias, I., Di Marzo, V., Köfalvi, A., 2008, 10.1007/978-0-387-74349-3_14
  • Endocannabinoids: Some like it fat (and sweet too), Matias, I., Cristino, L., Di Marzo, V., 2008, 10.1111/j.1365-2826.2008.01678.x
  • Endocannabinoids: Synthesis and degradation, Di Marzo, V., 2008, 10.1007/112-0505
  • FAAH and anandamide: is 2-AG really the odd one out?, Di Marzo, V., Maccarrone, M., 2008, 10.1016/j.tips.2008.03.001
  • Functional lipidomics. Calcium-independent activation of endocannabinoid/endovanilloid lipid signalling in sensory neurons by protein kinases C and A and thrombin, Vellani, V., Petrosino, S., De Petrocellis, L., Valenti, M., Prandini, M., Magherini, P.C., McNaughton, P.A., Di Marzo, V., 2008, 10.1016/j.neuropharm.2008.01.010
  • Gender-dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: A possible role for the endocannabinoid system, Llorente, R., Llorente-Berzal, A., Petrosino, S., Marco, E.-M., Guaza, C., Prada, C., López-Gallardo, M., Di Marzo, V., Viveros, M.-P., 2008, 10.1002/dneu.20666
  • Immunohistochemical localization of anabolic and catabolic enzymes for anandamide and other putative endovanilloids in the hippocampus and cerebellar cortex of the mouse brain, Cristino, L., Starowicz, K., De Petrocellis, L., Morishita, J., Ueda, N., Guglielmotti, V., Di Marzo, V., 2008, 10.1016/j.neuroscience.2007.11.047
  • Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon, Izzo, A.A., Aviello, G., Petrosino, S., Orlando, P., Marsicano, G., Lutz, B., Borrelli, F., Capasso, R., Nigam, S., Capasso, F., Di Marzo, V., 2008, 10.1007/s00109-007-0248-4
  • Inhibitory effect of salvinorin A, from Salvia divinorum, on ileitis-induced hypermotility: Cross-talk between κ-opioid and cannabinoid CB 1 receptors, Capasso, R., Borrelli, F., Cascio, M.G., Aviello, G., Huben, K., Zjawiony, J.K., Marini, P., Romano, B., Di Marzo, V., Capasso, F., Izzo, A.A., 2008, 10.1038/bjp.2008.294
  • Inhibitory effect of the anorexic compound oleoylethanolamide on gastric emptying in control and overweight mice, Aviello, G., Matias, I., Capasso, R., Petrosino, S., Borrelli, F., Orlando, P., Romano, B., Capasso, F., Di Marzo, V., Izzo, A.A., 2008, 10.1007/s00109-008-0305-7
  • Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo, Pasquini, S., Botta, L., Semeraro, T., Mugnaini, C., Ligresti, A., Palazzo, E., Maione, S., Di Marzo, V., Corelli, F., 2008, 10.1021/jm800552f
  • Neuronal and glial alterations in the cerebellar cortex of maternally deprived rats: Gender differences and modulatory effects of two inhibitors of endocannabinoid inactivation, López-Gallardo, M., Llorente, R., Llorente-Berzal, A., Marco, E.M., Prada, C., Di Marzo, V., Viveros, M.P., 2008, 10.1002/dneu.20672
  • New analgesics synthetically derived from the paracetamol metabolite N-(4-hydroxyphenyl)-(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-enamide, Sinning, C., Watzer, B., Coste, O., Nüsing, R.M., Ott, I., Ligresti, A., Di Marzo, V., Imming, P., 2008, 10.1021/jm800807k
  • New tetrazole-based selective anandamide uptake inhibitors, Ortar, G., Schiano Moriello, A., Cascio, M.G., De Petrocellis, L., Ligresti, A., Morera, E., Nalli, M., Di Marzo, V., 2008, 10.1016/j.bmcl.2008.04.003
  • Plant-derived cannabinoids modulate the activity of transient receptor potential channels of ankyrin type-1 and melastatin type-8, De Petrocellis, L., Vellani, V., Schiano-Moriello, A., Marini, P., Magherini, P.C., Orlando, P., Di Marzo, V., 2008, 10.1124/jpet.107.134809
  • Play an ADAGIO with a STRADIVARIUS: The right patient for CB1 receptor antagonists?, Di Marzo, V., 2008, 10.1038/ncpcardio1319
  • Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: Insulin and melanocortins, Matias, I., Vergoni, A.V., Petrosino, S., Ottani, A., Pocai, A., Bertolini, A., Di Marzo, V., 2008, 10.1016/j.neuropharm.2007.06.011
  • Rimonabant in rats with a metabolic syndrome: Good news after the depression, Di Marzo, V., Szallasi, A., 2008, 10.1038/bjp.2008.170
  • Role in anxiety behavior of the endocannabinoid system in the prefrontal cortex, Rubino, T., Realini, N., Castiglioni, C., Guidali, C., Viganó, D., Marras, E., Petrosino, S., Perletti, G., Maccarrone, M., Di Marzo, V., Parolaro, D., 2008, 10.1093/cercor/bhm161
  • Study of the regulation of the endocannabinoid system in a virus model of multiple sclerosis reveals a therapeutic effect of palmitoylethanolamide, Loría, F., Petrosino, S., Mestre, L., Spagnolo, A., Correa, F., Hernangómez, M., Guaza, C., Di Marzo, V., Docagne, F., 2008, 10.1111/j.1460-9568.2008.06377.x
  • Symptom-related changes of endocannabinoid and palmitoylethanolamide levels in brain areas of R6/2 mice, a transgenic model of Huntington's disease, Bisogno, T., Martire, A., Petrosino, S., Popoli, P., Di Marzo, V., 2008, 10.1016/j.neuint.2007.06.031
  • Synthesis, cannabinoid receptor affinity, and molecular modeling studies of substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides, Silvestri, R., Cascio, M.G., La Regina, G., Piscitelli, F., Lavecchia, A., Brizzi, A., Pasquini, S., Botta, M., Novellino, E., Di Marzo, V., Corelli, F., 2008, 10.1021/jm070566z
  • Targeting the endocannabinoid system: To enhance or reduce?, Di Marzo, V., 2008, 10.1038/nrd2553
  • Tetrahydrolipstatin analogues as modulators of endocannabinoid 2-arachidonoylglycerol metabolism, Ortar, G., Bisogno, T., Ligresti, A., Morera, E., Nalli, M., Di Marzo, V., 2008, 10.1021/jm800978m
  • The analgesic effect of N-arachidonoyl-serotonin, a FAAH inhibitor and TRPV1 receptor antagonist, associated with changes in rostral ventromedial medulla and locus coeruleus cell activity in rats, de Novellis, V., Palazzo, E., Rossi, F., De Petrocellis, L., Petrosino, S., Guida, F., Luongo, L., Migliozzi, A., Cristino, L., Marabese, I., Starowicz, K., Di Marzo, V., Maione, S., 2008, 10.1016/j.neuropharm.2008.06.023
  • The anandamide membrane transporter inhibitor, VDM-11, modulates sleep and c-Fos expression in the rat brain, Murillo-Rodríguez, E., Millán-Aldaco, D., Di Marzo, V., Drucker-Colín, R., 2008, 10.1016/j.neuroscience.2008.08.056
  • The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling, Tam, J., Trembovler, V., Di Marzo, V., Petrosino, S., Leo, G., Alexandrovich, A., Regev, E., Casap, N., Shteyer, A., Ledent, C., Karsak, M., Zimmer, A., Mechoulam, R., Yirmiya, R., Shohami, E., Bab, I., 2008, 10.1096/fj.06-7957com
  • The CB1 cannabinoid receptor antagonist AM251 attenuates amphetamine-induced behavioural sensitization while causing monoamine changes in nucleus accumbens and hippocampus, Thiemann, G., Di Marzo, V., Molleman, A., Hasenöhrl, R.U., 2008, 10.1016/j.pbb.2008.01.010
  • The endocannabinoid 2-arachidonoylglycerol is responsible for the slow self-inhibition in neocortical interneurons, Marinelli, S., Pacioni, S., Bisogno, T., Di Marzo, V., Prince, D.A., Huguenard, J.R., Bacci, A., 2008, 10.1523/JNEUROSCI.0847-08.2008
  • The endocannabinoid system in obesity and type 2 diabetes, Di Marzo, V., 2008, 10.1007/s00125-008-1048-2
  • The role of endocannabinoids in the regulation of gastric emptying: Alterations in mice fed a high-fat diet, Di Marzo, V., Capasso, R., Matias, I., Aviello, G., Petrosino, S., Borrelli, F., Romano, B., Orlando, P., Capasso, F., Izzo, A.A., 2008, 10.1038/sj.bjp.0707682
  • The role of the CB1 cannabinoid receptor and its endogenous ligands, anandamide and 2-arachidonoylglycerol, in amphetamine-induced behavioural sensitization, Thiemann, G., van der Stelt, M., Petrosino, S., Molleman, A., Di Marzo, V., Hasenöhrl, R.U., 2008, 10.1016/j.bbr.2007.09.022
  • The role of the endocannabinoid system in alzheimer's disease: Facts and hypotheses, Bisogno, T., Di Marzo, V., 2008, 10.2174/138161208785740027
  • TRPV1 receptors in the central nervous system: Potential for previously unforseen therapeutic applications, Starowicz, K., Cristino, L., Di Marzo, V., 2008, 10.2174/138161208783330790
  • Why endocannabinoids are not all alike, Di Marzo, V., Cristino, L., 2008, 10.1038/nn0208-124
  • Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors, Maione, S., De Petrocellis, L., De Novellis, V., Moriello, A.S., Petrosino, S., Palazzo, E., Rossi, F.S., Woodward, D.F., Di Marzo, V., 2007, 10.1038/sj.bjp.0707145
  • Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret, Sharkey, K.A., Cristino, L., Oland, L.D., Van Sickle, M.D., Starowicz, K., Pittman, Q.J., Guglielmotti, V., Davison, J.S., Di Marzo, V., 2007, 10.1111/j.1460-9568.2007.05521.x
  • Attenuation of allergic contact dermatitis through the endocannabinoid system, Karsak, M., Gaffal, E., Date, R., Wang-Eckhardt, L., Rehnelt, J., Petrosino, S., Starowicz, K., Steuder, R., Schlicker, E., Cravatt, B., Mechoulam, R., Buettner, R., Werner, S., Di Marzo, V., Tüting, T., Zimmer, A., 2007, 10.1126/science.1142265
  • Biochemistry and pharmacology of endovanilloids, Starowicz, K., Nigam, S., Di Marzo, V., 2007, 10.1016/j.pharmthera.2007.01.005
  • Cannabinoid CB1 receptor stimulation affords neuroprotection in MPTP-induced neurotoxicity by attenuating S100B up-regulation in vitro, Iuvone, T., Esposito, G., De Filippis, D., Bisogno, T., Petrosino, S., Scuderi, C., Di Marzo, V., Steardo, L., 2007, 10.1007/s00109-007-0233-y
  • Changes in spinal and supraspinal endocannabinoid levels in neuropathic rats, Petrosino, S., Palazzo, E., de Novellis, V., Bisogno, T., Rossi, F., Maione, S., Di Marzo, V., 2007, 10.1016/j.neuropharm.2006.08.011
  • Circulating endocannabinoid levels, abdominal adiposity and related cardiometabolic risk factors in obese men, Côté, M., Matias, I., Lemieux, I., Petrosino, S., Alméras, N., Després, J.-P., Di Marzo, V., 2007, 10.1038/sj.ijo.0803539
  • Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors, Brizzi, A., Cascio, M.G., Brizzi, V., Bisogno, T., Dinatolo, M.T., Martinelli, A., Tuccinardi, T., Di Marzo, V., 2007, 10.1016/j.bmc.2007.05.060
  • Enantioselective synthesis and vanilloid activity evaluation of 1-β-(p-methoxycinnamoyl)polygodial, an antinociceptive compound from Drymis winteri barks, Della Monica, C., De Petrocellis, L., Di Marzo, V., Landi, R., Izzo, I., Spinella, A., 2007, 10.1016/j.bmcl.2007.10.001
  • Enantioselective synthesis of 1-(R)-hydroxypolygodial and its 9α epimer, 1-(R)-hydroxyisotadeonal, Della Monica, C., Della Sala, G., Izzo, I., De Petrocellis, L., di Marzo, V., Spinella, A., 2007, 10.1016/j.tet.2007.04.059
  • Endocannabinoids and Related Compounds: Walking Back and Forth between Plant Natural Products and Animal Physiology, Di Marzo, V., Bisogno, T., De Petrocellis, L., 2007, 10.1016/j.chembiol.2007.05.014
  • Endocannabinoids and the control of energy balance, Matias, I., Di Marzo, V., 2007, 10.1016/j.tem.2006.11.006
  • Endocannabinoids and the regulation of their levels in health and disease, Di Marzo, V., Petrosino, S., 2007, 10.1097/MOL.0b013e32803dbdec
  • Identification of endocannabinoids and related compounds in human fat cells, Gonthier, M.-P., Hoareau, L., Festy, F., Matias, I., Volenti, M., Bès-Houtmann, S., Rouch, C., Robert-Da Silva, C., Chesne, S., D'Hellencourt, C.L., Césari, M., Di Marzo, V., Roche, R., 2007, 10.1038/oby.2007.581
  • Mechanisms for the coupling of cannabinoid receptors to intracellular calcium mobilization in rat insulinoma β-cells, De Petrocellis, L., Marini, P., Matias, I., Moriello, A.S., Starowicz, K., Cristino, L., Nigam, S., Di Marzo, V., 2007, 10.1016/j.yexcr.2007.05.012
  • Metabolically labile cannabinoid esters: A 'soft drug' approach for the development of cannabinoid-based therapeutic drugs, Minutolo, F., Cascio, M.G., Carboni, I., Bisogno, T., Prota, G., Bertini, S., Digiacomo, M., Bifulco, M., Di Marzo, V., Macchia, M., 2007, 10.1016/j.bmcl.2007.06.055
  • N-arachidonoyl-dopamine tunes synaptic transmission onto dopaminergic neurons by activating both cannabinoid and vanilloid receptors, Marinelli, S., Di Marzo, V., Florenzano, F., Fezza, F., Viscomi, M.T., Van Der Stelt, M., Bernardi, G., Molinari, M., Maccarrone, M., Mercuri, N.B., 2007, 10.1038/sj.npp.1301118
  • New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists, Manera, C., Cascio, M.G., Benetti, V., Allarà, M., Tuccinardi, T., Martinelli, A., Saccomanni, G., Vivoli, E., Ghelardini, C., Di Marzo, V., Ferrarini, P.L., 2007, 10.1016/j.bmcl.2007.09.089
  • New N-arachidonoylserotonin analogues with potential "dual" mechanism of action against pain, Ortar, G., Cascio, M.G., De Petrocellis, L., Morera, E., Rossi, F., Schiano-Moriello, A., Nalli, M., De Novellis, V., Woodward, D.F., Maione, S., Di Marzo, V., 2007, 10.1021/jm070678q
  • Opposing control of cannabinoid receptor stimulation on amyloid-β-induced reactive gliosis: In vitro and in vivo evidence, Esposito, G., Iuvone, T., Savani, C., Scuderi, C., De Filippis, D., Papa, M., Di Marzo, V., Steardo, L., 2007, 10.1124/jpet.107.121566
  • Overactivity of the intestinal endocannabinoid system in celiac disease and in methotrexate-treated rats, D'Argenio, G., Petrosino, S., Gianfrani, C., Valenti, M., Scaglione, G., Grandone, I., Nigam, S., Sorrentini, I., Mazzarella, G., Di Marzo, V., 2007, 10.1007/s00109-007-0192-3
  • Palmitoylethanolamide, endocannabinoids and related cannabimimetic compounds in protection against tissue inflammation and pain: Potential use in companion animals, Re, G., Barbero, R., Miolo, A., Di Marzo, V., 2007, 10.1016/j.tvjl.2005.10.003
  • Periaqueductal gray metabotropic glutamate receptor subtype 7 and 8 mediate opposite effects on amino acid release, rostral ventromedial medulla cell activities, and thermal nociception, Marabese, I., Rossi, F., Palazzo, E., De Novellis, V., Starowicz, K., Cristino, L., Vita, D., Gatta, L., Guida, F., Di Marzo, V., Rossi, F., Maione, S., 2007, 10.1152/jn.00356.2007
  • Pharmacological enhancement of the endocannabinoid system in the nucleus accumbens shell stimulates food intake and increases c-Fos expression in the hypothalamus, Soria-Gómez, E., Matias, I., Rueda-Orozco, P.E., Cisneros, M., Petrosino, S., Navarro, L., Di Marzo, V., Prospéro-García, O., 2007, 10.1038/sj.bjp.0707313
  • Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): Effect of cAMP, cannabinoid CB1 receptors and endovanilloids, De Petrocellis, L., Starowicz, K., Moriello, A.S., Vivese, M., Orlando, P., Di Marzo, V., 2007, 10.1016/j.yexcr.2007.01.008
  • Role and regulation of acylethanolamides in energy balance: Focus on adipocytes and β-cells, Matias, I., Gonthier, M.-P., Petrosino, S., Docimo, L., Capasso, R., Hoareau, L., Monteleone, P., Roche, R., Izzo, A.A., Di Marzo, V., 2007, 10.1038/sj.bjp.0707424
  • Short- and long-term plasticity of the endocannabinoid system in neuropsychiatric and neurological disorders, Bisogno, T., Di Marzo, V., 2007, 10.1016/j.phrs.2007.09.002
  • Structure-based virtual screening: Identification of novel CB2 receptor ligands, Tuccinardi, T., Cascio, M.G., Di Marzo, V., Manera, C., Ortore, G., Saccomanni, G., Martinelli, A., 2007, 10.2174/157018007778992829
  • The 1,2,3-triazole ring as a peptido- and olefinomimetic element: Discovery of click yanilloids and cannabinoids, Appendino, G., Bacchiega, S., Minassi, A., Cascio, M.G., De Petrocellis, L., Di Marzo, V., 2007, 10.1002/anie.200703590
  • The endocannabinoid system for the development of new drugs for spasticity, Di Marzo, V., 2007, 10.1358/dof.2007.032.04.1083482
  • A brief history of cannabinoid and endocannabinoid pharmacology as inspired by the work of British scientists, Di Marzo, V., 2006, 10.1016/j.tips.2006.01.010
  • A role for vanilloid receptor 1 (TRPV1) and endocannabinnoid signalling in the regulation of spontaneous and L-DOPA induced locomotion in normal and reserpine-treated rats, Lee, J., Di Marzo, V., Brotchie, J.M., 2006, 10.1016/j.neuropharm.2006.04.016
  • Anandamide inhibits adhesion and migration of breast cancer cells, Grimaldi, C., Pisanti, S., Laezza, C., Malfitano, A.M., Santoro, A., Vitale, M., Caruso, M.G., Notarnicola, M., Iacuzzo, I., Portella, G., Di Marzo, V., Bifulco, M., 2006, 10.1016/j.yexcr.2005.10.024
  • Antitumor activity of plant cannabinoids with emphasis on the effect of cannabidiol on human breast carcinoma, Ligresti, A., Moriello, A.S., Starowicz, K., Matias, I., Pisanti, S., De Petrocellis, L., Laezza, C., Portella, G., Bifulco, M., Di Marzo, V., 2006, 10.1124/jpet.106.105247
  • Arvanil inhibits T lymphocyte activation and ameliorates autoimmune encephalomyelitis, Malfitano, A.M., Matarese, G., Pisanti, S., Grimaldi, C., Laezza, C., Bisogno, T., Di Marzo, V., Lechler, R.I., Bifulco, M., 2006, 10.1016/j.jneuroim.2005.09.005
  • Cannabinoid CB1 receptor mediates fear extinction via habituation-like processes, Kamprath, K., Marsicano, G., Tang, J., Monory, K., Bisogno, T., Di Marzo, V., Lutz, B., Wotjak, C.T., 2006, 10.1523/JNEUROSCI.0153-06.2006
  • Changes in endocannabinoid and palmitoylethanolamide levels in eye tissues of patients with diabetic retinopathy and age-related macular degeneration, Matias, I., Wang, J.W., Moriello, A.S., Nieves, A., Woodward, D.F., Di Marzo, V., 2006, 10.1016/j.plefa.2006.08.002
  • Depolarization-induced retrograde synaptic inhibition in the mouse cerebellar cortex is mediated by 2-arachidonoylglycerol, Szabo, B., Urbanski, M.J., Bisogno, T., Di Marzo, V., Mendiguren, A., Baer, W.U., Freiman, I., 2006, 10.1113/jphysiol.2006.119362
  • Development of the first potent and specific inhibitors of endocannabinoid biosynthesis, Bisogno, T., Cascio, M.G., Saha, B., Mahadevan, A., Urbani, P., Minassi, A., Appendino, G., Saturnino, C., Martin, B., Razdan, R., Di Marzo, V., 2006, 10.1016/j.bbalip.2005.12.009
  • Development of the first potential covalent inhibitors of anandamide cellular uptake, Moriello, A.S., Balas, L., Ligresti, A., Cascio, M.G., Durand, T., Morera, E., Ortar, G., Di Marzo, V., 2006, 10.1021/jm051226l
  • Elevation of endocannabinoid levels in the ventrolateral periaqueductal grey through inhibition of fatty acid amide hydrolase affects descending nociceptive pathways via both cannabinoid receptor type 1 and transient receptor potential vanilloid type-1 receptors, Maione, S., Bisogno, T., De Novellis, V., Palazzo, E., Cristino, L., Valenti, M., Petrosino, S., Guglielmotti, V., Rossi, F., Di Marzo, V., 2006, 10.1124/jpet.105.093286
  • Endocannabinoid overactivity and intestinal inflammation, Di Marzo, V., Izzo, A.A., 2006, 10.1136/gut.2005.090472
  • Endocannabinoid synthesis and degradation, and their regulation in the framework of energy balance., Matias, I., Di Marzo, V., 2006
  • Endocannabinoids activate transient receptor potential vanilloid 1 receptors to reduce hyperdopaminergia-related hyperactivity: Therapeutic implications, Tzavara, E.T., Li, D.L., Moutsimilli, L., Bisogno, T., Di Marzo, V., Phebus, L.A., Nomikos, G.G., Giros, B., 2006, 10.1016/j.biopsych.2005.08.019
  • Endocannabinoids and β-amyloid-induced neurotoxicity in vivo: Effect of pharmacological elevation of endocannabinoid levels, Van Der Stelt, M., Mazzola, C., Esposito, G., Matias, I., Petrosino, S., De Filippis, D., Micale, V., Steardo, L., Drago, F., Iuvone, T., Di Marzo, V., 2006, 10.1007/s00018-006-6037-3
  • Endocannabinoids, feeding and suckling - From our perspective, Mechoulam, R., Berry, E.M., Avraham, Y., Di Marzo, V., Fride, E., 2006, 10.1038/sj.ijo.0803274
  • Endogenous cannabinoids in the brain and peripheral tissues: Regulation of their levels and control of food intake, Matias, I., Bisogno, T., Di Marzo, V., 2006, 10.1038/sj.ijo.0803271
  • Evolutionary origins of the endocannabinoid system, McPartland, J.M., Matias, I., Di Marzo, V., Glass, M., 2006, 10.1016/j.gene.2005.11.004
  • First "hybrid" ligands of vanilloid TRPV1 and cannabinoid CB 2 receptors and non-polyunsaturated fatty acid-derived CB 2-selective ligands, Appendino, G., Cascio, M.G., Bacchiega, S., Moriello, A.S., Minassi, A., Thomas, A., Ross, R., Pertwee, R., De Petrocellis, L., Di Marzo, V., 2006, 10.1016/j.febslet.2005.12.069
  • Forebrain-specific inactivation of Gq/G11 family G proteins results in age-dependent epilepsy and impaired endocannabinoid formation, Wettschureck, N., Van Der Stelt, M., Tsubokawa, H., Krestel, H., Moers, A., Petrosino, S., Schütz, G., Di Marzo, V., Offermanns, S., 2006, 10.1128/MCB.00397-06
  • Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain, Cristino, L., de Petrocellis, L., Pryce, G., Baker, D., Guglielmotti, V., Di Marzo, V., 2006, 10.1016/j.neuroscience.2006.02.074
  • In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands, Cascio, M.G., Bisogno, T., Palazzo, E., Thomas, A., Van Der Stelt, M., Brizzi, A., De Novellis, V., Marabese, I., Ross, R., Van De Doelen, T., Brizzi, V., Pertwee, R., Maione, S., Di Marzo, V., 2006, 10.1038/sj.bjp.0706888
  • Increasing cannabinoid levels by pharmacological and genetic manipulation delay disease progression in SOD1 mice, Bilsland, L.G., Dick, J.R.T., Pryce, G., Petrosino, S., Di Marzo, V., Baker, D., Greensmith, L., 2006, 10.1096/fj.05-4743fje
  • Iodinated N-acylvanillamines: Potential "multiple-target" anti-inflammatory agents acting via the inhibition of T-cell activation and antagonism at vanilloid TRPV1 channels, Ḿarquez, N., De Petrocellis, L., Caballero, F.J., Macho, A., Schiano-Moriello, A., Minassi, A., Appendino, G., Mũnoz, E., Di Marzo, V., 2006, 10.1124/mol.105.019786
  • Neural contractions in colonic strips from patients with diverticular disease: Role of endocannabinoids and substance P, Guagnini, F., Valenti, M., Mukenge, S., Matias, I., Bianchetti, A., Di Palo, S., Ferla, G., Di Marzo, V., Croci, T., 2006, 10.1136/gut.2005.076372
  • Neuropathic pain and the endocannabinoid system in the dorsal raphe: Pharmacological treatment and interactions with the serotonergic system, Palazzo, E., De Novellis, V., Petrosino, S., Marabese, I., Vita, D., Giordano, C., Di Marzo, V., Mangoni, G.S., Rossi, F., Maione, S., 2006, 10.1111/j.1460-9568.2006.05086.x
  • New metabolically stable fatty acid amide ligands of cannabinoid receptors: Synthesis and receptor affinity studies, Urbani, P., Cavallo, P., Cascio, M.G., Buonerba, M., De Martino, G., Di Marzo, V., Saturnino, C., 2006, 10.1016/j.bmcl.2005.09.023
  • New potent and selective inhibitors of anandamide reuptake with antispastic activity in a mouse model of multiple sclerosis, Ligresti, A., Cascio, M.G., Pryce, G., Kulasegram, S., Beletskaya, I., De Petrocellis, L., Saha, B., Mahadevan, A., Visintin, C., Wiley, J.L., Baker, D., Martin, B.R., Razdan, R.K., Di Marzo, V., 2006, 10.1038/sj.bjp.0706418
  • Oxyhomologues of anandamide and related endolipids: Chemoselective synthesis and biological activity, Appendino, G., Minassi, A., Berton, L., Moriello, A.S., Cascio, M.G., De Petrocellis, L., Di Marzo, V., 2006, 10.1021/jm051240y
  • Plant, synthetic, and endogenous cannabinoids in medicine, Di Marzo, V., De Petrocellis, L., 2006, 10.1146/annurev.med.57.011205.135648
  • Protective activation of the endocannabinoid system during ischemia in dopamine neurons, Melis, M., Pillolla, G., Bisogno, T., Minassi, A., Petrosino, S., Perra, S., Muntoni, A.L., Lutz, B., Gessa, G.L., Marsicano, G., Di Marzo, V., Pistis, M., 2006, 10.1016/j.nbd.2006.04.010
  • Regulation, function, and dysregulation of endocannabinoids in models of adipose and β-pancreatic cells and in obesity and hyperglycemia, Matias, I., Gonthier, M.-P., Orlando, P., Martiadis, V., De Petrocellis, L., Cervino, C., Petrosino, S., Hoareau, L., Festy, F., Pasquali, R., Roche, R., Maj, M., Pagotto, U., Monteleone, P., Di Marzo, V., 2006, 10.1210/jc.2005-2679
  • Synthesis, conformational analysis and CB1 binding affinity of hairpin-like anandamide pseudopeptide mimetics, Di Marzo, M., Casapullo, A., Bifulco, G., Cimino, P., Ligresti, A., Di Marzo, V., Riccio, R., Gomez-Paloma, L., 2006, 10.1002/psc.754
  • The endocannabinoid and endovanilloid systems and their interactions in neuropathic pain, Maione, S., Starowicz, K., Palazzo, E., Rossi, F., Di Marzo, V., 2006, 10.1002/ddr.20098
  • Up-regulation of anandamide levels as an endogenous mechanism and a pharmacological strategy to limit colon inflammation, D'Argenio, G., Valenti, M., Scaglione, G., Cosenza, V., Sorrentini, I., Di Marzo, V.D., 2006, 10.1096/fj.05-4943fje
  • Viewpoint: The endocannabinoid system, Di Marzo, V., 2006
  • A role for endocannabinoids in the generation of parkinsonism and levodopa-induced dyskinesia in MPTP-lesioned non-human primate models of Parkinson's disease, Van Der Stelt, M., Fox, S.H., Hill, M., Crossman, A.R., Petrosino, S., Di Marzo, V., Brotchie, J.M., 2005, 10.1096/fj.04-3010fje
  • Activation of the endocannabinoid system as therapeutic approach in a murine model of multiple sclerosis, Ortega-Gutiérrez, S., Molina-Holgado, E., Árevalo-Martín, Á., Correa, F., Viso, A., López-Rodríguez, M.L., Di Marzo, V., Guaza, C., 2005, 10.1096/fj.04-2464fje
  • Anandamide acts as an intracellular messenger amplifying Ca2+ influx via TRPV1 channels, Van Der Stelt, M., Trevisani, M., Vellani, V., De Petrocellis, L., Moriello, A.S., Campi, B., McNaughton, P., Geppetti, P., Di Marzo, V., 2005, 10.1038/sj.emboj.7600784
  • Anandamide as an intracellular messenger regulating ion channel activity, Van Der Stelt, M., Di Marzo, V., 2005, 10.1016/j.prostaglandins.2004.09.007
  • Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease, De Lago, E., Urbani, P., Ramos, J.A., Di Marzo, V., Fernández-Ruiz, J., 2005, 10.1016/j.brainres.2005.05.024
  • Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa, Monteleone, P., Matias, I., Martiadis, V., De Petrocellis, L., Maj, M., Di Marzo, V., 2005, 10.1038/sj.npp.1300695
  • Cannabinoid receptors and their role in neuroprotection, Van Der Stelt, M., Di Marzo, V., 2005
  • Cisplatin increases brain 2-arachidonoylglycerol (2-AG) and concomitantly reduces intestinal 2-AG and anandamide levels in the least shrew, Darmani, N.A., McClanahan, B.A., Trinh, C., Petrosino, S., Valenti, M., Di Marzo, V., 2005, 10.1016/j.neuropharm.2005.04.007
  • Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis, Cabranes, A., Venderova, K., De Lago, E., Fezza, F., Sánchez, A., Mestre, L., Valenti, M., García-Merino, A., Ramos, J.A., Di Marzo, V., Fernández-Ruiz, J., 2005, 10.1016/j.nbd.2005.03.002
  • Development of the first ultra-potent "capsaicinoid" agonist at transient receptor potential vanilloid type 1 (TRPV1) channels and its therapeutic potential, Appendino, G., De Petrocellis, L., Trevisani, M., Minassi, A., Daddario, N., Moriello, A.S., Gazzieri, D., Ligresti, A., Campi, B., Fontana, G., Pinna, C., Geppetti, P., Di Marzo, V., 2005, 10.1124/jpet.104.074864
  • Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels, De Lago, E., Petrosino, S., Valenti, M., Morera, E., Ortega-Gutierrez, S., Fernandez-Ruiz, J., Di Marzo, V., 2005, 10.1016/j.bcp.2005.05.011
  • Endocannabinoid control of food intake and energy balance, Di Marzo, V., Matias, I., 2005, 10.1038/nn1457
  • Endocannabinoid metabolic pathways and enzymes, Ligresti, A., Cascio, M.G., Di Marzo, V., 2005
  • Erratum: Anandamide acts as an intracellular messenger amplifying Ca 2+ influx via TRPV1 channels (EMBO Journal (2005) 24 (3026-3037) DOI: 10.1038/sj.emboj.7600784, Van Der Stelt, M., Trevisani, M., Vellani, V., De Petrocellis, L., Schiano Moriello, A., Campi, B., McNaughton, P., Geppetti, P., Di Marzo, V., 2005, 10.1038/sj.emboj.7600839
  • Fatty acid amide hydrolase controls mouse intestinal motility in vivo, Capasso, R., Matias, I., Lutz, B., Borrelli, F., Capasso, F., Marsicano, G., Mascolo, N., Petrosino, S., Monory, K., Valenti, M., Di Marzo, V., Izzo, A.A., 2005, 10.1053/j.gastro.2005.06.018
  • Finding of endocannabinoids in human eye tissues: Implications for glaucoma, Chen, J., Matias, I., Dinh, T., Lu, T., Venezia, S., Nieves, A., Woodward, D.F., Di Marzo, V., 2005, 10.1016/j.bbrc.2005.03.095
  • Involvement of the cannabimimetic compound, N-palmitoyl-ethanolamine, in inflammatory and neuropathic conditions: Review of the available pre-clinical data, and first human studies, Darmani, N.A., Izzo, A.A., Degenhardt, B., Valenti, M., Scaglione, G., Capasso, R., Sorrentini, I., Di Marzo, V., 2005, 10.1016/j.neuropharm.2005.01.001
  • Lipids as regulators of the activity of transient receptor potential type V1 (TRPV1) channels, De Petrocellis, L., Di Marzo, V., 2005, 10.1016/j.lfs.2005.05.021
  • Mechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamine, Sancho, R., De La Vega, L., Macho, A., Appendino, G., Di Marzo, V., Muñoz, E., 2005
  • Neuroscience: Identification and functional characterization of brainstem cannabinoid CB2 receptors, Van Sickle, M.D., Duncan, M., Kingsley, P.J., Mouihate, A., Urbani, P., Mackie, K., Stella, N., Makriyannis, A., Piomelli, D., Davison, J.S., Marnett, L.J., Di Marzo, V., Pittman, Q.J., Patel, K.D., Sharkey, K.A., 2005, 10.1126/science.1115740
  • Occurrence and possible biological role of the endocannabinoid system in the sea squirt Ciona intestinalis, Matias, I., McPartland, J.M., Di Marzo, V., 2005, 10.1111/j.1471-4159.2005.03103.x
  • Pharmacological modulation of the endocannabinoid system in a viral model of multiple sclerosis, Mestre, L., Correa, F., Arévalo-Martín, A., Molina-Holgado, E., Valenti, M., Ortar, G., Di Marzo, V., Guaza, C., 2005, 10.1111/j.1471-4159.2004.02979.x
  • Targeted lipidomics: Endocannabinoids and other endolipid modulators, Rapaka, R.S., Makriyannis, A., Di Marzo, V., Piomelli, D., 2005, 10.1016/j.lfs.2005.05.001
  • The biosynthesis, fate and pharmacological properties of endocannabinoids, Di Marzo, V., Bisogno, T., De Petrocellis, L., 2005, 10.1007/3-540-26573-2-5
  • The endocannabinoid signalling system: Biochemical aspects, Bisogno, T., Ligresti, A., Di Marzo, V., 2005, 10.1016/j.pbb.2005.01.027
  • The endocannabinoid system and its therapeutic exploitations | Das endocannabinoid-system und seine therapeutische nutzung, Di Marzo, V., Bifulco, M., De Petrocellis, L., 2005
  • The endocannabinoid system in the brain of Carassius auratus and its possible role in the control of food intake, Valenti, M., Cottone, E., Martinez, R., De Pedro, N., Rubio, M., Viveros, M.P., Franzoni, M.F., Delgado, M.J., Di Marzo, V., 2005, 10.1111/j.1471-4159.2005.03406.x
  • The taming of capsaicin. Reversal of the vanilloid activity of N-acylvanillamines by aromatic iodination, Appendino, G., Daddario, N., Minassi, A., Moriello, A.S., De Petrocellis, L., Di Marzo, V., 2005, 10.1021/jm050139q
  • Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility, Maccarrone, M., Fride, E., Bisogno, T., Bari, M., Cascio, M.G., Battista, N., Finazzi Agrò, A., Suris, R., Mechoulam, R., Di Marzo, V., 2005, 10.1093/molehr/gah130
  • A new strategy to block tumor growth by inhibiting endocannabinoid inactivation, Bifulco, M., Laezza, C., Valenti, M., Ligresti, A., Portella, G., Di Marzo, V., 2004, 10.1096/fj.04-1754fje
  • A structure-activity relationship study on N -arachidonoyl-amino acids as possible endogenous inhibitors of fatty acid amide hydrolase, Cascio, M.G., Minassi, A., Ligresti, A., Appendino, G., Burstein, S., Di Marzo, V., 2004, 10.1016/j.bbrc.2003.12.075
  • Actions of two naturally occurring saturated N-acyldopamines on transient receptor potential vanilloid 1 (TRPV1) channels, De Petrocellis, L., Chu, C.J., Schiano Moriello, A., Kellner, J.C., Walker, J.M., Di Marzo, V., 2004, 10.1038/sj.bjp.0705924
  • Behavioral and molecular changes elicited by acute administration of SR141716 to Δ9-tetrahydrocannabinol-tolerant rats: An experimental model of cannabinoid abstinence, González, S., Fernández-Ruiz, J., Di Marzo, V., Hernández, M., Arévalo, C., Nicanor, C., Cascio, M.G., Ambrosio, E., Ramos, J.A., 2004, 10.1016/j.drugalcdep.2003.12.011
  • Changes in endocannabinoid contents in reward-related brain regions of alcohol-exposed rats, and their possible relevance to alcohol relapse, González, S., Valenti, M., De Miguel, R., Fezza, F., Fernández-Ruiz, J., Di Marzo, V., Ramos, J.A., 2004, 10.1038/sj.bjp.0705963
  • Changes in endocannabinoid levels in a rat model of behavioural sensitization to morphine, Viganò, D., Valenti, M., Cascio, M.G., Di Marzo, V., Parolaro, D., Rubino, T., 2004, 10.1111/j.1460-9568.2004.03645.x
  • Differential diurnal variations of anandamide and 2-arachidonoyl-glycerol levels in rat brain, Valenti, M., Viganò, D., Cascio, M.G., Rubino, T., Steardo, L., Parolaro, D., Di Marzo, V., 2004, 10.1007/s00018-003-3453-5
  • Endocannabinoids link feeding state and auditory perception-related gene expression, Soderstrom, K., Tian, Q., Valenti, M., Di Marzo, V.D., 2004, 10.1523/JNEUROSCI.3298-04.2004
  • Endovanilloids: Putative endogenous ligands of transient receptor potential vanilloid 1 channels, Van Der Stelt, M., Di Marzo, V., 2004, 10.1111/j.1432-1033.2004.04081.x
  • Further evidence for the existence of a specific process for the membrane transport of anandamide, Ligresti, A., Morera, E., Van Der Stelt, M., Monory, K., Lutz, B., Ortar, G., Di Marzo, V., 2004, 10.1042/BJ20031812
  • In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake, De Lago, E., Ligresti, A., Ortar, G., Morera, E., Cabranes, A., Pryce, G., Bifulco, M., Baker, D., Fernandez-Ruiz, J., Di Marzo, V., 2004, 10.1016/j.ejphar.2003.11.027
  • Lipopolysaccharide-induced pulmonary inflammation is not accompanied by a release of anandamide into the lavage fluid or a down-regulation of the activity of fatty acid amide hydrolase, Holt, S., Rocksén, D., Bucht, A., Petersen, G., Hansen, H.S., Valenti, M., Di Marzo, V., J. Fowler, C., 2004, 10.1016/j.lfs.2004.09.005
  • Metabolic fate of endocannabinoids, van der Stelt, M., Di Marzo, V., 2004, 10.2174/1570159043476864
  • Prefrontal cortex stimulation induces 2-arachidonoyl-glycerol-mediated suppression of excitation in dopamine neurons, Melis, M., Perra, S., Muntoni, A.L., Pillolla, G., Lutz, B., Marsicano, G., Di Marzo, V., Gessa, G.L., Pistis, M., 2004, 10.1523/JNEUROSCI.3502-04.2004
  • Prostaglandin Ethanolamides (Prostamides): In Vitro Pharmacology and Metabolism, Matias, I., Chen, J., De Petrocellis, L., Bisogno, T., Ligresti, A., Fezza, F., Krauss, A.H.-P., Shi, L., Protzman, C.E., Li, C., Liang, Y., Nieves, A.L., Kedzie, K.M., Burk, R.M., Di Marzo, V., Woodward, D.F., 2004, 10.1124/jpet.103.061705
  • Selective inhibition of anandamide cellular uptake versus enzymatic hydrolysis - A difficult issue to handle, Fowler, C.J., Tiger, G., Ligresti, A., López-Rodríguez, M.L., Di Marzo, V., 2004, 10.1016/j.ejphar.2004.03.048
  • Synthesis and biological evaluation of phorbol-resiniferatoxin (RTX) hybrids, Appendino, G., Bertolino, A., Minassi, A., Annunziata, R., Szallasi, A., De Petrocellis, L., Di Marzo, V., 2004, 10.1002/ejoc.200400122
  • The anandamide membrane transporter. Structureâ€"activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region, Di Marzo, V., Ligresti, A., Morera, E., Nalli, M., Ortar, G., 2004, 10.1016/j.bmc.2004.07.026
  • The endocannabinoid system and its therapeutic exploitation, Di Marzo, V., Bifulco, M., De Petrocellis, L., 2004, 10.1038/nrd1495
  • The endocannabinoid system: A general view and latest additions, De Petrocellis, L., Cascio, M.G., Di Marzo, V., 2004, 10.1038/sj.bjp.0705666
  • An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice, Izzo, A.A., Capasso, F., Costagliola, A., Bisogno, T., Marsicano, G., Ligresti, A., Matias, I., Capasso, R., Pinto, L., Borrelli, F., Cecio, A., Lutz, B., Mascolo, N., Di Marzo, V., 2003, 10.1016/S0016-5085(03)00892-8
  • Anandamide inhibits nuclear factor-κB activation through a cannabinoid receptor-independent pathway, Sancho, R., Calzado, M.A., Di Marzo, V., Appendino, G., Muñoz, E., 2003, 10.1124/mol.63.2.429
  • Capsaicin-like effects of N-arachidonoyl-dopamine in the isolated guinea pig bronchi and urinary bladder, Harrison, S., De Petrocellis, L., Trevisani, M., Benvenuti, F., Bifulco, M., Geppetti, P., Di Marzo, V., 2003, 10.1016/S0014-2999(03)02114-9
  • CB1 cannabinoid receptors and on-demand defense against excitotoxicity, Marsicano, G., Goodenough, S., Monory, K., Hermann, H., Eder, M., Cannich, A., Azad, S.C., Cascio, M.G., Gutiérrez, S.O., Van der Stelt, M., López-Rodríguez, M.L., Casanova, E., Schütz, G., Zieglgänsberger, W., Di Marzo, V., Behl, C., Lutz, B., 2003, 10.1126/science.1088208
  • Chronic morphine modulates the contents of the endocannabinoid, 2-arachidonoyl glycerol, in rat brain., Viganò, D., Grazia Cascio, M., Rubino, T., Fezza, F., Vaccani, A., Di Marzo, V., Parolaro, D., 2003
  • Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain, Bisogno, T., Howell, F., Williams, G., Minassi, A., Cascio, M.G., Ligresti, A., Matias, I., Schiano-Moriello, A., Paul, P., Williams, E.-J., Gangadbaran, U., Hobbs, C., Di Marzo, V., Doherty, P., 2003, 10.1083/jcb.200305129
  • Compounds acting at the endocannabinoid and/or endovanilloid systems reduce hyperkinesia in a rat model of Huntington's disease, Lastres-Becker, I., De Miguel, R., De Petrocellis, L., Makriyannis, A., Di Marzo, V., Fernández-Ruiz, J., 2003, 10.1046/j.1471-4159.2003.01595.x
  • Dual effect of cannabinoid CB1 receptor stimulation on a vanilloid VR1 receptor-mediated response, Hermann, H., De Petrocellis, L., Bisogno, T., Moriello, A.S., Lutz, B., Di Marzo, V., 2003, 10.1007/s000180300052
  • Effect of maternal under-nutrition on pup body weight and hypothalamic endocannabinoid levels, Matias, I., Léonhardt, M., Lesage, J., De Petrocellis, L., Dupouy, J.-P., Vieau, D., Di Marzo, V., 2003, 10.1007/s000180300031
  • Endocannabinoid signalling in the blood of patients with schizophrenia, De Marchi, N., De Petrocellis, L., Orlando, P., Daniele, F., Fezza, F., Di Marzo, V., 2003, 10.1186/1476-511X-2-1
  • Endocannabinoids and related fatty acid amides, and their regulation, in the salivary glands of the lone star tick, Fezza, F., Dillwith, J.W., Bisogno, T., Tucker, J.S., Di Marzo, V., Sauer, J.R., 2003, 10.1016/S1388-1981(03)00087-8
  • Erratum: Corrigendum to Halogenation of a capsaicin analogue leads to novel vanilloid TRPVI receptor antagonists (British Journal Pharmacology (2003) 139 (1417-1424)), Appendino, G., Harrison, S., De Petrocellis, L., Daddario, N., Bianchi, F., Moriello, A.S., Trevisani, M., Benvenuti, F., Geppetti, P., Di Marzo, V., 2003, 10.1038/sj.bjp.0705565
  • Halogenation of a capsaicin analogue leads to novel vanilloid TRPV1 receptor antagonists, Appendino, G., Harrison, S., De Petrocellis, L., Daddario, N., Bianchi, F., Moriello, A.S., Trevisani, M., Benvenuti, F., Geppetti, P., Di Marzo, V., 2003, 10.1038/sj.bjp.0705387
  • Homologues and isomers of noladin ether, a putative novel endocannabinoid: Interaction with rat cannabinoid CB1 receptors, Appendino, G., Ligresti, A., Minassi, A., Daddario, N., Bisogno, T., Di Marzo, V., 2003, 10.1016/S0960-894X(02)00839-9
  • Inhibitory effects of cannabinoid CB1 receptor stimulation on tumor growth and metastatic spreading: actions on signals involved in angiogenesis and metastasis., Portella, G., Laezza, C., Laccetti, P., De Petrocellis, L., Di Marzo, V., Bifulco, M., 2003
  • Manipulation of the endocannabinoid system by a general anaesthetic, Di Marzo, V., 2003, 10.1038/sj.bjp.0705333
  • N-oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia, Chu, C.J., Huang, S.M., De Petrocellis, L., Bisogno, T., Ewing, S.A., Miller, J.D., Zipkin, R.E., Daddario, N., Appendino, G., Di Marzo, V., Walker, J.M., 2003, 10.1074/jbc.M211231200
  • Neuromodulatory actions of endocannabinoids in pain and sedation, De Petrocellis, L., Bisogno, T., Di Marzo, V., 2003
  • Neuroprotection by the endogenous cannabinoid anandamide and arvanil against in vivo excitotoxicity in the rat: Role of vanilloid receptors and lipoxygenases, Veldhuis, W.B., Van der Stelt, M., Wadman, M.W., Van Zadelhoff, G., Maccarrone, M., Fezza, F., Veldink, G.A., Vliegenthart, J.F.G., Bär, P.R., Nicolay, K., Di Marzo, V., 2003
  • Novel selective and metabolically stable inhibitors of anandamide cellular uptake, Ortar, G., Ligresti, A., De Petrocellis, L., Morera, E., Di Marzo, V., 2003, 10.1016/S0006-2952(03)00109-6
  • Possible endocannabinoid control of colorectal cancer growth, Ligresti, A., Bisogno, T., Matias, I., De Petrocellis, L., Cascio, M.G., Cosenza, V., D'Argenio, G., Scaglione, G., Bifulco, M., Sorrentini, I., Di Marzo, V., 2003, 10.1016/S0016-5085(03)00881-3
  • Presynaptic facilitation of glutamatergic synapses to dopaminergic neurons of the rat substantia nigra by endogenous stimulation of vanilloid receptors, Marinelli, S., Di Marzo, V., Berretta, N., Matias, I., Maccarrone, M., Bernardi, G., Mercuri, N.B., 2003
  • Semiplenamides A-G, Fatty Acid Amides from a Papua New Guinea Collection of the Marine Cyanobacterium Lyngbya semiplena, Han, B., McPhail, K.L., Ligresti, A., Di Marzo, V., Gerwick, W.H., 2003, 10.1021/np030242n
  • The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase-8-dependent pathway, Sancho, R., De La Vega, L., Appendino, G., Di Marzo, V., Macho, A., Muñoz, E., 2003, 10.1038/sj.bjp.0705532
  • The endocannabinoid system as a target for the development of new drugs for cancer therapy | Il sistema endocannabinoide quale bersaglio di terapie anti-tumorali. Conoscenze attuali e prospettive, Bifulco, M., Di Marzo, V., 2003
  • The endocannabinoid system in the basal ganglia and in the mesolimbic reward system: Implications for neurological and psychiatric disorders, Van Der Stelt, M., Di Marzo, V., 2003, 10.1016/j.ejphar.2003.08.101
  • A structure/activity relationship study on arvanil, an endocannabinoid and vanilloid hybrid, Di Marzo, V., Griffin, G., De Petrocellis, L., Brandi, I., Bisogno, T., Williams, W., Grier, M.C., Kulasegram, S., Mahadevan, A.N.U., Razdan, R.K., Martin, B.R., 2002, 10.1124/jpet.300.3.984
  • Acute neuronal injury, excitotoxicity, and the endocannabinoid system, Van der Stelt, M., Veldhuis, W.B., Maccarrone, M., Bär, P.R., Nicolay, K., Veldink, G.A., Di Marzo, V., Vliegenthart, J.F.G., 2002, 10.1385/MN:26:2-3:317
  • An endogenous capsaicin-like substance with high potency at recombinant and native vanilloid VR1 receptors, Huang, S.M., Bisogno, T., Trevisani, M., Al-Hayani, A., De Petrocellis, L., Fezza, F., Tognetto, M., Petros, T.J., Krey, J.F., Chu, C.J., Miller, J.D., Davies, S.N., Geppetti, P., Walker, J.M., Di Marzo, V., 2002, 10.1073/pnas.122196999
  • Anandamide receptors, Di Marzo, V., De Petrocellis, L., Fezza, F., Ligresti, A., Bisogno, T., 2002, 10.1054/plef.2001.0349
  • Arvanil-induced inhibition of spasticity and persistent pain: Evidence for therapeutic sites of action different from the vanilloid VR1 receptor and cannabinoid CB1/CB2 receptors, Brooks, J.W., Pryce, G., Bisogno, T., Jaggar, S.I., Hankey, D.J.R., Brown, P., Bridges, D., Ledent, C., Bifulco, M., Rice, A.S.C., Di Marzo, V., Baker, D., 2002, 10.1016/S0014-2999(02)01369-9
  • Cannabimimetic eicosanoids in cancer and inflammation: An update, Melck, D., Bisogno, T., De Petrocellis, L., Beaulieu, P., Rice, A.S.C., Di Marzo, V., 2002
  • Changes in endocannabinoid contents in the brain of rats chronically exposed to nicotine, ethanol or cocaine, González, S., Grazia Cascio, M., Fernández-Ruiz, J., Fezza, F., Di Marzo, V., Ramos, J.A., 2002, 10.1016/S0006-8993(02)03344-9
  • Effect on cancer cell proliferation of palmitoylethanolamide, a fatty acid amide interacting with both the cannabinoid and vanilloid signalling systems, De Petrocellis, L., Bisogno, T., Ligresti, A., Bifulco, M., Melck, D., Di Marzo, V., 2002, 10.1046/j.1472-8206.2002.00094.x
  • Endocannabinoid levels in rat limbic forebrain and hypothalamus in relation to fasting, feeding and satiation: Stimulation of eating by 2-arachidonoyl glycerol, Kirkham, T.C., Williams, C.M., Fezza, F., Di Marzo, V., 2002
  • Endocannabinoids 3. Diseases of peripheral organs involving the endocannabinoid system and their possible treatment with endocannabinoid-based drugs, Di Marzo, V., Matias, I., De Petrocellis, L., 2002
  • Endocannabinoids as physiological regulators of colonic propulsion in mice, Pinto, L., Izzo, A.A., Cascio, M.G., Bisogno, T., HospodarScott, K., Brown, D.R., Mascolo, N., Di Marzo, V., Capasso, F., 2002, 10.1053/gast.2002.34242
  • Endocannabinoids in the new millennium, Di Marzo, V., 2002, 10.1054/plef.2001.0339
  • Endovanilloid signaling in pain, Di Marzo, V., Blumberg, P.M., Szallasi, A., 2002, 10.1016/S0959-4388(02)00340-9
  • Erratum: "The hypothalamic levels of the endocannabinoid, anandamide, peak immediately before the onset of puberty in female rats" (Life Sciences (2002) 70:12 (1407-1414) PII: S0024320501015168), Wenger, T., Gerendai, I., Fezza, F., González, S., Bisogno, T., Fernandez-Ruiz, J., Di Marzo, V., 2002, 10.1016/S0024-3205(02)01800-3
  • Fatty acids amide hydrolase, an enzyme with many bioactive substrates. Possible therapeutic implications, Bisogno, T., De Petrocellis, L., Di Marzo, V., 2002, 10.2174/1381612023395655
  • Low fatty acid amide hydrolase and high anandamide levels are associated with failure to achieve an ongoing pregnancy after IVF and embryo transfer, Maccarrone, M., Bisogno, T., Valensise, H., Lazzarin, N., Fezza, F., Manna, C., Di Marzo, V., Finazzi-Agrò, A., 2002
  • N-acylvanillamides: Development of an expeditious synthesis and discovery of new acyl templates for powerful activation of the vanilloid receptor, Appendino, G., Minassi, A., Morello, A.S., De Petrocellis, L., Di Marzo, V., 2002, 10.1021/jm020844o
  • Noladin ether, a putative novel endocannabinoid: Inactivation mechanisms and a sensitive method for its quantification in rat tissues, Fezza, F., Bisogno, T., Minassi, A., Appendino, G., Mechoulam, R., Di Marzo, V., 2002, 10.1016/S0014-5793(02)02341-4
  • Presence and regulation of the endocannabinoid system in human dendritic cells, Matias, I., Pochard, P., Orlando, P., Salzet, M., Pestel, J., Di Marzo, V., 2002, 10.1046/j.1432-1033.2002.03078.x
  • Targeting the endocannabinoid system in cancer therapy: A call for further research, Bifulco, M., Di Marzo, V., 2002, 10.1038/nm0602-547
  • The endocannabinoid system and the molecular basis of paralytic ileus in mice., Mascolo, N., Izzo, A.A., Ligresti, A., Costagliola, A., Pinto, L., Cascio, M.G., Maffia, P., Cecio, A., Capasso, F., Di Marzo, V., 2002
  • The endocannabinoid system protects rat glioma cells against HIV-1 Tat protein-induced cytotoxicity: Mechanism and regulation, Esposito, G., Ligresti, A., Izzo, A.A., Bisogno, T., Ruvo, M., Di Rosa, M., Di Marzo, V., Iuvone, T., 2002, 10.1074/jbc.M207170200
  • The endogenous cannabinoid system controls extinction of aversive memories, Marsicano, G., Wotjak, C.T., Azad, S.C., Bisogno, T., Rammes, G., Cascioll, M.G., Hermann, H., Tang, J., Hofmann, C., Zieglgänsberger, W., Di Marzo, V., Lutz, B., 2002, 10.1038/nature00839
  • The hypothalamic levels of the endocannabinoid, anandamide, peak immediately before the onset of puberty in female rats, Wenger, T., Gerendai, I., Fezza, F., González, S., Bisogno, T., Fernandez-Ruiz, J., Di Marzo, V., 2002, 10.1016/S0024-3205(01)01516-8
  • Anandamide and diet: Inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets, Berger, A., Crozier, G., Bisogno, T., Cavaliere, P., Innis, S., Di Marzo, V., 2001, 10.1073/pnas.101119098
  • Anandamide: Some like it hot, Di Marzo, V., Bisogno, T., De Petrocellis, L., 2001, 10.1016/S0165-6147(00)01712-0
  • Cannabinoid CB 1-receptor mediated regulation of gastrointestinal motility in mice in a model of intestinal inflammation, Izzo, A.A., Fezza, F., Capasso, R., Bisogno, T., Pinto, L., Iuvone, T., Esposito, G., Mascolo, N., Di Marzo, V., Capasso, F., 2001
  • Control by the endogenous cannabinoid system of ras oncogene-dependent tumor growth., Bifulco, M., Laezza, C., Portella, G., Vitale, M., Orlando, P., De Petrocellis, L., Di Marzo, V., 2001
  • Critical role of the endogenous cannabinoid system in mouse pup suckling and growth, Fride, E., Ginzburg, Y., Breuer, A., Bisogno, T., Di Marzo, V., Mechoulam, R., 2001, 10.1016/S0014-2999(01)00953-0
  • Endocannabinoids control spasticity in a multiple sclerosis model., Baker, D., Pryce, G., Croxford, J.L., Brown, P., Pertwee, R.G., Makriyannis, A., Khanolkar, A., Layward, L., Fezza, F., Bisogno, T., Di Marzo, V., 2001
  • Endocannabinoids Part II: Pathological CNS conditions involving the endocannabinoid system and their possible treatment with endocannabinoid-based drugs, Di Marzo, V., Bisogno, T., Petrocellis, L.D., 2001, 10.1517/14728222.5.3.349
  • Erratum: Anandamide and diet: Inclusion of dietary arachidonate and docosahexaenoate leads to increased brain levels of the corresponding N-acylethanolamines in piglets (Proceedings of the National Academy of Sciences of the United States of America (May 22, 2001) 98:11 (6402-6406)), Berger, A., Crozier, G., Bisogno, T., Cavaliere, P., Innis, S., Di Marzo, V., 2001
  • Evidence for a new G protein-coupled cannabinoid receptor in mouse brain, Breivogel, C.S., Griffin, G., Di Marzo, V., Martin, B.R., 2001
  • Evidence for an endocannabinoid system in the central nervous system of the leech Hirudo medicinalis, Matias, I., Bisogno, T., Melck, D., Vandenbulcke, F., Verger-Bocquet, M., De Petrocellis, L., Sergheraert, C., Breton, C., Di Marzo, V., Salzet, M., 2001, 10.1016/S0169-328X(00)00290-4
  • Exogenous anandamide protects rat brain against acute neuronal injury in vivo, Van Der Stelt, M., Veldhuis, W.B., Van Haaften, G.W., Fezza, F., Bisogno, T., Bär, P.R., Veldink, G.A., Vliegenthart, J.F.G., Di Marzo, V., Nicolay, K., 2001
  • Highly selective CB1 cannabinoid receptor ligands and novel CB1/VR1 vanilloid receptor "hybrid" ligands, Di Marzo, V., Bisogno, T., De Petrocellis, L., Brandi, I., Jefferson, R.G., Winckler, R.L., Davis, J.B., Dasse, O., Mahadevan, A., Razdan, R.K., Martin, B.R., 2001, 10.1006/bbrc.2001.4354
  • Hypolocomotor effects in rats of capsaicin and two long chain capsaicin homologues, Di Marzo, V., Lastres-Becker, I., Bisogno, T., De Petrocellis, L., Milone, A., Davis, J.B., Fernandez-Ruiz, J.J., 2001, 10.1016/S0014-2999(01)01012-3
  • Identification of a New Class of Molecules, the Arachidonyl Amino Acids, and Characterization of One Member That Inhibits Pain, Huang, S.M., Bisogno, T., Petros, T.J., Chang, S.Y., Zavitsanos, P.A., Zipkin, R.E., Sivakumar, R., Coop, A., Maeda, D.Y., De Petrocellis, L., Burstein, S., Di Marzo, V., Walker, J.M., 2001, 10.1074/jbc.M107351200
  • Inhibitory effect of palmitoylethanolamide on gastrointestinal motility in mice, Capasso, R., Izzo, A.A., Fezza, F., Pinto, A., Capasso, F., Mascolo, N., Di Marzo, V., 2001
  • Leptin-regulated endocannabinoids are involved in maintaining food intake, Di Marzo, V., Goparaju, S.K., Wang, L., Liu, J., Bátkai, S., Járai, Z., Fezza, F., Miura, G.I., Palmiter, R.D., Sugiura, T., Kunos, G., 2001, 10.1038/35071088
  • Lipids in neural function: modulation of behavior by oral administration of endocannabinoids found in foods., Crozier Willi, G., Berger, A., Di Marzo, V., Bisogno, T., De Petrocellis, L., Fride, E., Mechoulam, R., 2001
  • Lipopolysaccharide downregulates fatty acid amide hydrolase expression and increases anandamide levels in human peripheral lymphocytes, Maccarrone, M., De Petrocellis, L., Bari, M., Fezza, F., Salvati, S., Di Marzo, V., Finazzi-Agrò, A., 2001, 10.1006/abbi.2001.2500
  • Molecular targets for cannabidiol and its synthetic analogues: Effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide, Bisogno, T., Hanuš, L., De Petrocellis, L., Tchilibon, S., Ponde, D.E., Brandi, I., Moriello, A.S., Davis, J.B., Mechoulam, R., Di Marzo, V., 2001
  • Normal human pituitary gland and pituitary adenomas express cannabinoid receptor type 1 and synthesize endogenous cannabinoids: First evidence for a direct role of cannabinoids on hormone modulation at the human pituitary level, Pagotto, U., Marsicano, G., Fezza, F., Theodoropoulou, M., Grübler, Y., Stalla, J., Arzberger, T., Milone, A., Losa, M., Di Marzo, V., Lutz, B., Stalla, G.K., 2001, 10.1210/jc.86.6.2687
  • Palmitoylethanolamide enhances anandamide stimulation of human vanilloid VR1 receptors, De Petrocellis, L., Davis, J.B., Di Marzo, V., 2001, 10.1016/S0014-5793(01)02934-9
  • Palmitoylethanolamide inhibits the expression of fatty acid amide hydrolase and enhances the anti-proliferative effect of anandamide in human breast cancer cells, Di Marzo, V., Melck, D., Orlando, P., Bisogno, T., Zagoory, O., Bifulco, M., Vogel, Z., De Petrocellis, L., 2001, 10.1042/0264-6021:3580249
  • Structure-activity relationship for the endogenous cannabinoid, anandamide, and certain of its analogues at vanilloid receptors in transfected cells and vas deferens, Ross, R.A., Gibson, T.M., Brockie, H.C., Leslie, M., Pashmi, G., Craib, S.J., Di Marzo, V., Pertwee, R.G., 2001
  • Synthesis and biological evaluation of novel amides of polyunsaturated fatty acids with dopamine, Bezuglov, V., Bobrov, M., Gretskaya, N., Gonchar, A., Zinchenko, G., Melck, D., Bisogno, T., Di Marzo, V., Kuklev, D., Rossi, J.-C., Vidal, J.-P., Durand, T., 2001, 10.1016/S0960-894X(00)00689-2
  • The Activity of Anandamide at Vanilloid VR1 Receptors Requires Facilitated Transport across the Cell Membrane and Is Limited by Intracellular Metabolism, De Petrocellis, L., Bisogno, T., Maccarrone, M., Davis, J.B., Finazzi-Agrò, A., Di Marzo, V., 2001, 10.1074/jbc.M008555200
  • The vanilloid receptor (VR1)-mediated effects of anandamide are potently enhanced by the cAMP-dependent protein kinase, De Petrocellis, L., Harrison, S., Bisogno, T., Tognetto, M., Brandi, I., Smith, G.D., Creminon, C., Davis, J.B., Geppetti, P., Di Marzo, V., 2001, 10.1046/j.1471-4159.2001.00406.x
  • Anandamide - The other side of the coin, Zygmunt, P.M., Julius, D., Di Marzo, V., Högestätt, E.D., 2000, 10.1016/S0165-6147(99)01430-3
  • Anandamide and other cannabimimetic fatty acid derivatives - Foreword, Di Marzo, V., Yamamoto, S., 2000, 10.1016/S0090-6980(00)00050-2
  • Anandamide uptake by human endothelial cells and its regulation by nitric oxide, Maccarrone, M., Bari, M., Lorenzon, T., Bisogno, T., Di Marzo, V., Finazzi-Agrò, A., 2000, 10.1074/jbc.275.18.13484
  • Cannabimimetic fatty acid derivatives in cancer and inflammation, Di Marzo, V., Melck, D., De Petrocellis, L., Bisogno, T., 2000, 10.1016/S0090-6980(00)00054-X
  • Cannabinoid properties of methylfluorophosphonate analogs, Martin, B.R., Beletskaya, I., Patrick, G., Jefferson, R., Winckler, R., Deutsch, D.G., Di Marzo, V., Dasse, O., Mahadevan, A., Razdan, R.K., 2000
  • Comparative biology of the endocannabinoid system: Possible role in the immune response, Salzet, M., Breton, C., Bisogno, T., Di Marzo, V., 2000, 10.1046/j.1432-1327.2000.01550.x
  • Endocannabinoids and fatty acid amides in cancer, inflammation and related disorders, De Petrocellis, L., Melck, D., Bisogno, T., Di Marzo, V., 2000, 10.1016/S0009-3084(00)00196-1
  • Endocannabinoids and multiple sclerosis: A blessing from the 'inner bliss'?, Di Marzo, V., Bifulco, M., De Petrocellis, L., 2000, 10.1016/S0165-6147(00)01487-5
  • Endocannabinoids: New targets for drug development, Di Marzo, V., Bisogno, T., De Petrocellis, L., 2000
  • Enhanced levels of endogenous cannabinoids in the globus pallidus are associated with a reduction in movement in an animal model of Parkinson's disease, Di Marzo, V., Hill, M.P., Bisogno, T., Crossman, A.R., Brotchie, J.M., 2000
  • Enhancement of anandamide formation in the limbic forebrain and reduction of endocannabinoid contents in the striatum of Δ9- tetrahydrocannabinol-tolerant rats, Di Marzo, V., Berrendero, F., Bisogno, T., González, S., Cavaliere, P., Romero, J., Cebeira, M., Ramos, J.A., Fernández-Ruiz, J.J., 2000, 10.1046/j.1471-4159.2000.0741627.x
  • Enzymological and molecular biological studies on anandamide amidohydrolase, Ueda, N., Katayama, K., Kurahashi, Y., Suzuki, M., Suzuki, H., Yamamoto, S., Katoh, I., Di Marzo, V., De Petrocellis, L., 2000
  • Levels, metabolism, and pharmacological activity of anandamide in CB1 cannabinoid receptor knockout mice: Evidence for non-CB1, non-CB2 receptor-mediated actions of anandamide in mouse brain, Di Marzo, V., Breivogel, C.S., Tao, Q., Bridgen, D.T., Razdan, R.K., Zimmer, A.M., Zimmer, A., Martin, B.R., 2000, 10.1046/j.1471-4159.2000.0752434.x
  • N-acyl-dopamines: Novel synthetic CB1 cannabinoid-receptor ligands and inhibitors of anandamide inactivation with cannabimimetic activity in vitro and in vivo, Bisogno, T., Melck, D., Bobrov, M.Yu., Gretskaya, N.M., Bezuglov, V.V., De Petrocellis, L., Di Marzo, V., 2000, 10.1042/0264-6021:3510817
  • Neurobehavioral activity in mice of N-vanillyl-arachidonyl-amide, Di Marzo, V., Breivogel, C., Bisogno, T., Melck, D., Patrick, G., Tao, Q., Szallasi, A., Razdan, R.K., Martin, B.R., 2000, 10.1016/S0014-2999(00)00687-7
  • New perspectives on enigmatic vanilloid receptors, Szallasi, A., Di Marzo, V., 2000, 10.1016/S0166-2236(00)01630-1
  • Overlap between the ligand recognition properties of the anandamide transporter and the VR1 vanilloid receptor: Inhibitors of anandamide uptake with negligible capsaicin-like activity, De Petrocellis, L., Bisogno, T., Davis, J.B., Pertwee, R.G., Di Marzo, V., 2000, 10.1016/S0014-5793(00)02082-2
  • Role of the endogenous cannabinoid system in the formalin test of ersistent pain in the rat, Beaulieu, P., Bisogno, T., Punwar, S., Farquhar-Smith, W.P., Ambrosino, G., Di Marzo, V., Rice, A.S.C., 2000, 10.1016/S0014-2999(00)00226-0
  • Sex steroid influence on cannabinoid CB1 receptor mRNA and endocannabinoid levels in the anterior pituitary gland, González, S., Bisogno, T., Wenger, T., Manzanares, J., Milone, A., Berrendero, F., Di Marzo, V., Ramos, J.A., Fernández-Ruiz, J.J., 2000, 10.1006/bbrc.2000.2406
  • Analysis of cannabinoid receptor binding and mRNA expression and endogenous cannabinoid contents in the developing rat brain during late gestation and early postnatal period, Berrendero, F., Sepe, N., Ramos, J.A., Di Marzo, V., Fernández-Ruiz, J.J., 1999, 10.1002/(SICI)1098-2396(19990901)33:3<181::AID-SYN3>3.0.CO;2-R
  • Biosynthesis and inactivation of endocannabinoids: Relevance to their proposed role as neuromodulators, Di Marzo, V., 1999, 10.1016/S0024-3205(99)00287-8
  • Biosynthesis and inactivation of N-arachidonoylethanolamine (anandamide) and N-docosahexaenoylethanolamine in bovine retina, Bisogno, T., Delton-Vandenbroucke, I., Milone, A., Lagarde, M., Di Marzo, V., 1999, 10.1006/abbi.1999.1410
  • Biosynthesis and inactivation of the endocannabinoid 2- arachidonoylglycerol in circulating and tumoral macrophages, Di Marzo, V., Bisogno, T., De Petrocellis, L., Melck, D., Orlando, P., Wagner, J.A., George Kunos, 1999, 10.1046/j.1432-1327.1999.00631.x
  • Brain regional distribution of endocannabinoids: Implications for their biosynthesis and biological function, Bisogno, T., Berrendero, F., Ambrosino, G., Cebeira, M., Ramos, J.A., Fernandez-Ruiz, J.J., Di Marzo, V., 1999, 10.1006/bbrc.1999.0254
  • Cannabimimetic fatty acid derivatives: The anandamide family and other 'endocannabinoids', Di Marzo, V., Bisogno, T., De Petrocellis, L., Melck, D., Martin, B.R., 1999
  • Endocannabinoids: Endogenous cannabinoid receptor ligands with neuromodulatory action (Trends in Neurosciences (521-528) PII S016622369813831386), Di Marzo, V., Melck, D., Bisogno, T., De Petrocellis, L., 1999, 10.1016/S0166-2236(98)01383-6
  • Finding of the endocannabinoid signalling system in Hydra, a very primitive organism: Possible role in the feeding response, De Petrocellis, L., Melck, D., Bisogno, T., Milone, A., Di Marzo, V., 1999, 10.1016/S0306-4522(98)00749-0
  • Identification of endocannabinoids and cannabinoid CB1 receptor mRNA in the pituitary gland, González, S., Manzanares, J., Berrendero, F., Wenger, T., Corchero, J., Bisogno, T., Romero, J., Fuentes, J.A., Di Marzo, V., Ramos, J.A., Fernández-Ruiz, J.J., 1999, 10.1159/000054468
  • Involvement of the cAMP/protein kinase A pathway and of mitogen- activated protein kinase in the anti-proliferative effects of anandamide in human breast cancer cells, Melck, D., Rueda, D., Galve-Roperh, I., De Petrocellis, L., Guzmán, M., Di Marzo, V., 1999, 10.1016/S0014-5793(99)01639-7
  • Metabolism of anandamide and 2-arachidonoylglycerol: An historical overview and some recent developments, Di Marzo, V., De Petrocellis, L., Bisogno, T., Melck, D., 1999
  • Phosphatidic acid as the biosynthetic precursor of the endocannabinoid 2-arachidonoylglycerol in intact mouse neuroblastoma cells stimulated with ionomycin, Bisogno, T., Melck, D., De Petrocellis, L., Di Marzo, V., 1999, 10.1046/j.1471-4159.1999.0722113.x
  • The palmitoylethanolamide and oleamide enigmas: Are these two fatty acid amides cannabimimetic?, Lambert, D.M., Di Marzo, V., 1999
  • Unsaturated long-chain N-acyl-vanillyl-amides (N-AVAMs): Vanilloid receptor ligands that inhibit anandamide-facilitated transport and bind to CB1 cannabinoid receptors, Melck, D., Bisogno, T., De Petrocellis, L., Chuang, H.-H., Julius, D., Bifulco, M., Di Marzo, V., 1999, 10.1006/bbrc.1999.1105
  • Vanilloid receptors on sensory nerves mediate the vasodilator action of anandamide, Zygmunt, P.M., Petersson, J., Andersson, D.A., Chuang, H.-H., Sørgård, M., Di Marzo, V., Julius, D., Högestätt, E.D., 1999, 10.1038/22761
  • 'Endocannabinoids' and other fatty acid derivatives with cannabimimetic properties: Biochemistry and possible physiopathological relevance, Di Marzo, V., 1998, 10.1016/S0005-2760(98)00042-3
  • 2-arachidonoyl-glycerol as an "endocannabinoid": Limelight for a formerly neglected metabolite, Di Marzo, V., 1998
  • An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity, Ben-Shabat, S., Fride, E., Sheskin, T., Tamiri, T., Rhee, M.-H., Vogel, Z., Bisogno, T., De Petrocellis, L., Di Marzo, V., Mechoulam, R., 1998, 10.1016/S0014-2999(98)00392-6
  • Arachidonoylethyleneglycol and its nitroester as new cannabimimetics: Oxidation by 15-lipoxygenase and hydrolysis by fatty acid amide hydrolase, Bezuglov, V.V., Bobrov, M.Yu., Gretskaya, N.M., Archakov, A.V., Serkov, I.V., Fedenyuk, A.P., Verevochkina, E.Yu., Kogteva, G.S., Titova, O.Yu., Marvanov, D.M., De Petrocellis, L., Bisogno, T., Di Marzo, V., Manevich, Y., 1998
  • Arachidonoylethyleneglycol and its Nitroester as New Cannabimimetics: Oxidation by 15-Lipoxygenase and Hydrolysis by Fatty Acid Amide Hydrolase, Bezuglov, V.V., Bobrov, M.Yu., Gretskaya, N.M., Archakov, A.V., Serkov, I.V., Fedenyuk, A.P., Verevochkina, E.Yu., Kogteva, G.S., Titova, O.Yu., Marvanov, D.M., De Petrocellis, L., Bisogno, T., Di Marzo, V., Manevich, Y., 1998
  • Bioactive long chain N-acetylethanolamines in five species of edible bivalve molluscs. Possible implications for mollusc physiology and sea food industry, Sepe, N., De Petrocellis, L., Montanaro, F., Cimino, G., Di Marzo, V., 1998, 10.1016/S0005-2760(97)00132-X
  • Biochemistry of the endogenous ligands of cannabinoid receptors, Di Marzo, V., Deutsch, D.G., 1998, 10.1006/nbdi.1998.0214
  • Biosynthesis and degradation of bioactive fatty acid amides in human breast cancer and rat pheochromocytoma cells - Implications for cell proliferation and differentiation, Bisogno, T., Katayama, K., Melck, D., Ueda, N., De Petrocellis, L., Yamamoto, S., Di Marzo, V., 1998, 10.1046/j.1432-1327.1998.2540634.x
  • Endocannabinoids, Mechoulam, R., Fride, E., Di Marzo, V., 1998, 10.1016/S0014-2999(98)00649-9
  • Endocannabinoids: Endogenous cannabinoid receptor ligands with neuromodulatory action, Di Marzo, V., Melck, D., Bisogno, T., De Petrocellis, L., 1998, 10.1016/S0166-2236(98)01283-1
  • Interactions between synthetic vanilloids and the endogenous cannabinoid system, Di Marzo, V., Bisogno, T., Melck, D., Ross, R., Brockie, H., Stevenson, L., Pertwee, R., De Petrocellis, L., 1998, 10.1016/S0014-5793(98)01175-2
  • The endogenous cannabinoid anandamide inhibits human breast cancer cell proliferation, De Petrocellis, L., Melck, D., Palmisano, A., Bisogno, T., Laezza, C., Bifulco, M., Di Marzo, V., 1998, 10.1073/pnas.95.14.8375
  • The novel endogenous cannabinoid 2-arachidonoylglycerol is inactivated by neuronal- and basophil-like cells: Connections with anandamide, Di Marzo, V., Bisogno, T., Sugiura, T., Melck, D., De Petrocellis, L., 1998
  • Trick or treat from food endocannabinoids? [4] (multiple letters), Di Marzo, V., Sepe, N., De Petrocellis, L., Berger, A., Crozier, G., Fride, E., Mechoulam, R., Beltramo, M., Piomelli, D., 1998
  • V-K-ras leads to preferential farneaylation of p21ras in FRTL-5 cells: Multiple interference with the isoprenoid pathway, Bifulco, M., Laezza, C., Di Marzo, V., 1998
  • v-K-ras leads to preferential farnesylation of p21(ras) in FRTL-5 cells: Multiple Interference with the isoprenoid pathway, Laezza, C., Di Marzo, V., Bifulco, M., 1998, 10.1073/pnas.95.23.13646
  • Arachidonic acid as an endogenous signal for the glutathione-induced feeding response in Hydra, Pierobon, P., De Petrocellis, L., Minei, R., Di Marzo, V., 1997, 10.1007/PL00000580
  • Biosynthesis, release and degradation of the novel endogenous cannabimimetic metabolite 2-arachidonoylglycerol in mouse neuroblastoma cells, Bisogno, T., Sepe, N., Melck, D., Maurelli, S., De Petrocellis, L., Di Marzo, V., 1997
  • Biosynthesis, uptake, and degradation of anandamide and palmitoylethanolamide in leukocytes, Bisogno, T., Maurelli, S., Melck, D., De Petrocellis, L., Di Marzo, V., 1997, 10.1074/jbc.272.6.3315
  • Brain and peripheral anandamide amidohydrolase and its inhibition by synthetic arachidonate analogues, Di Marzo, V., 1997
  • Novel inhibitors of brain, neuronal, and basophilic anandamide amidohydrolase, De Petrocellis, L., Melck, D., Ueda, N., Maurelli, S., Kurahashi, Y., Yamamoto, S., Marino, G., Di Marzo, V., 1997, 10.1006/bbrc.1997.6000
  • Occurrence and metabolism of anandamide and related acyl-ethanolamides in ovaries of the sea urchin Paracentrotus lividus, Bisogno, T., Ventriglia, M., Milone, A., Mosca, M., Cimino, G., Di Marzo, V., 1997, 10.1016/S0005-2760(97)00009-X
  • The effects of anandamide on memory consolidation in mice involve both D1 and D2 dopamine receptors, Castellano, C., Cabib, S., Palmisano, A., Di Marzo, V., Puglisi-Allegra, S., 1997, 10.1097/00008877-199712000-00005
  • The sleep inducing factor oleamide is produced by mouse neuroblastoma cells, Bisogno, T., Sepe, N., De Petrocellis, L., Mechoulam, R., Di Marzo, V., 1997, 10.1006/bbrc.1997.7431
  • Biosynthesis of anandamide and related acylethanolamides in mouse J774 macrophages and N18 neuroblastoma cells, Di Marzo, V., De Petrocellis, L., Sepe, N., Buono, A., 1996
  • Novel diterpenoid diacylglycerols from marine molluscs: Potent morphogens and protein kinase C activators, De Petrocellis, L., Orlando, P., Gavagnin, M., Ventriglia, M., Cimino, G., Di Marzo, V., 1996
  • Occurrence and biosynthesis of 11(R)-hydroxy-eicosatetraenoic acid (11-R-HETE) in the Caribbean soft coral Plexaurella dichotoma, Di Marzo, V., Ventriglia, M., Mollo, E., Mosca, M., Cimino, G., 1996
  • Potential biosynthetic connections between the two cannabimimetic eicosanoids, anandamide and 2-arachidonoyl-glycerol, in mouse neuroblastoma cells, Marzo Di, V., De Petrocellis, L., Sugiura, T., Waku, K., 1996, 10.1006/bbrc.1996.1501
  • The endogenous cannabimimetic eicosanoid, anandamide, induces arachidonate release in J774 mouse macrophages, Di Marzo, V., De Petrocellis, L., Bisogno, T., Maurelli, S., 1996
  • ω10-lipoxygenase products of α-linolenic acid are esterified to phospholipids in Hydra vulgaris, Di Marzo, V., Vardaro, R.R., De Petrocellis, L., Cimino, G., 1996, 10.1007/BF01923355
  • Analysis of anandamide, an endogenous cannabinoid substance, and of other natural N-acylethanolamines, Fontana, A., Di Marzo, V., Cadas, H., Piomelli, D., 1995, 10.1016/0952-3278(95)90130-2
  • Anandamide, an endogenous cannabinomimetic eicosanoid: 'Killing two birds with one stone', Di Marzo, V., Fontana, A., 1995, 10.1016/0952-3278(95)90077-2
  • Anandamide, an endogenous cannabinomimetic substance, modulates rat brain protein kinase C in vitro, De Petrocellis, L., Orlando, P., Di Marzo, V., 1995
  • Arachidonic acid and eicosanoids as targets and effectors in second messenger interactions, Di Marzo, V., 1995, 10.1016/0952-3278(95)90123-X
  • Hydra vulgaris ω 10-lipoxygenase is used in vivo to synthesize new α-linoleic acid metabolites, Gianfrani, C., Di Marzo, V., De Petrocellis, L., Cimino, G., 1995, 10.1007/BF01964919
  • Pharmacology and physiology of the endogenous cannabimimetic mediator anandamide, Di Marzo, V., De Petrocellis, L., Bisogno, T., Maurelli, S., 1995
  • Phospholipase A2 and protein kinase C enzymatic activities and their interactions in Hydra vulgaris, Borrelli, L., Carginale, V., Capasso, A., Schneider, T., Leitz, T., De Petrocellis, L., Di Marzo, V., 1995, 10.1016/0305-0491(94)00243-N
  • Two novel classes of neuroactive fatty acid amides are substrates for mouse neuroblastoma 'anandamide amidohydrolase', Maurelli, S., Bisogno, T., De Petrocellis, L., Di Luccia, A., Marino, G., Di Marzo, V., 1995, 10.1016/0014-5793(95)01311-3
  • Aquatic invertebrates open up new perspectives in eicosanoid research: Biosynthesis and bioactivity, De Petrocellis, L., Di Marzo, V., 1994, 10.1016/0952-3278(94)90183-X
  • Enantiospecific synthesis of bioactive hydroxyeicosatetraenoic acids (HETEs) in Hydra magnipapillata, Leitz, T., Muller, W., De Petrocellis, L., Di Marzo, V., 1994, 10.1016/0005-2760(94)90029-9
  • Formation and inactivation of endogenous cannabinoid anandanide in central neurons, Di Marzo, V., Fontana, A., Cadas, H., Schinelli, S., Cimino, G., Schwartz, J.-C., Piomelli, D., 1994
  • Polyunsaturated-fatty-acid oxidation in Hydra: Regioselectivity, substratedependent enantioselectivity and possible biological role, Di Marzo, V., Gianfrani, C., De Petrocellis, L., Milone, A., Cimino, G., 1994
  • Possible involvement of arachidonic acid and eicosanoids in metamorphic events in Hydractinia echinata (Coelenterata; Hydrozoa), Leitz, T., Beck, H., Stephan, M., Lehmann, W.D., De Petrocellis, L., Di Marzo, V., 1994
  • Arachidonic acid, protein kinase C activators and bud formation in Hydra vulgaris, De Petrocellis, L., Di Marzo, V., Gianfrani, C., Minei, R., 1993, 10.1016/0742-8413(93)90198-T
  • Biosynthesis of hydroxyeicosatetraenoic acids (HETEs) in marine and freshwater hydroids, Di Marzo, V., Gianfrani, C., De Petrocellis, L., Milone, A., Villani, G., Cimino, G., 1993, 10.1016/0305-0491(93)90048-A
  • Biosynthesis, structure and biological activity of hydroxyeicosatetraenoic acids in Hydra vulgaris, Di Marzo, V., De Petrocellis, L., Gianfrani, C., Cimino, G., 1993
  • Dopamine D2 receptor signaling via the arachidonic acid cascade: modulation by cAMP-dependent protein kinase A and prostaglandin E2., Piomelli, D., Di Marzo, V., 1993
  • Histological and biochemical bases of defense mechanisms in four species of Polybranchioidea ascoglossan molluscs, Di Marzo, V., Marin, A., Vardaro, R.R., De Petrocellis, L., Villani, G., Cimino, G., Marine Biology, 1993, 10.1007/BF00349312
  • Selection of alternative G(i)-mediated signaling pathways at the dopamine D2 receptor by protein kinase C, Di Marzo, V., Vial, D., Sokoloff, P., Schwartz, J.-C., Piomelli, D., Journal of Neuroscience, 1993
  • The possible involvement of protein kinase C and phospholipase A2 in Hydra tentacle regeneration, De Petrocellis, L., Di Marzo, V., Cimino, G., 1993
  • Participation of prostaglandin E2 in dopamine D2 receptor-dependent potentiation of arachidonic acid release, Di Marzo, V., Piomelli, D., 1992
  • Placidenes: cyercene-like polypropionate γ-pyrones from the mediterranean ascoglossan mollusc Placida dendritica, Vardaro, R.R., Di Marzo, V., Cimino, G., Tetrahedron Letters, 1992, 10.1016/S0040-4039(00)78884-8
  • Prostaglandin F-1,15-lactone fatty acyl esters: a prostaglandin lactone pathway branch developed during the reproduction and early larval stages of a marine mollusc, Di Marzo, V., Minardi, C., Vardaro, R.R., Mollo, E., Cimino, G., 1992, 10.1016/0305-0491(92)90164-M
  • The effect of a cAMP analogue on Ca2+ ionophore-, antigen- and agonist-induced inositol phosphate release in rat basophilic leukemia (RBL-1) cells, Galadari, S.H.J., Morris, H.R., Di Marzo, V., 1992, 10.1016/0167-4889(92)90072-J
  • α-and γ-Pyrone-poly·propionates from the mediterranean ascoglossan mollusc ercolania funerea, Vardaro, R.R., Di Marzo, V., Marin, A., Cimino, G., 1992, 10.1016/S0040-4020(01)88324-1
  • A histological and chemical study of the cerata of the opisthobranch mollusc Tethys fimbria, Marin, A., Di Marzo, V., Cimino, G., 1991, 10.1007/BF01319406
  • A marine mollusc provides the first example of in vivo storage of prostaglandins: Prostaglandin-1,15-lactones, Cimino, G., Crispino, A., Di Marzo, V., Sodano, G., Spinella, A., Villani, G., 1991, 10.1007/BF02041252
  • A novel multifunctional metabolic pathway in a marine mollusc leads to unprecedented prostaglandin derivatives (prostaglandin 1,15-lactones), Di Marzo, V., Cimino, G., Crispino, A., Minardi, C., Sodano, G., Spinella, A., 1991
  • A novel prostaglandin metabolic pathway from a marine mollusc: prostaglandin-1,15-lactones., Di Marzo, V., Cimino, G., Sodano, G., Spinella, A., Villani, G., 1991
  • Cyercenes, novel polypropionate pyrones from the autotomizing mediterranean mollusc cyerce cristallina, Vardaro, R.R., Di Marzo, V., Crispino, A., Cimino, G., 1991, 10.1016/S0040-4020(01)80988-1
  • Cyercenes, novel pyrones from the ascoglossan mollusc Cyerce cristallina. Tissue distribution, biosynthesis and possible involvement in defense and regenerative processes, Di Marzo, V., Vardaro, R.R., De Petrocellis, L., Villani, G., Minei, R., Cimino, G., 1991
  • Minireview: Interactions between second messengers: Cyclic AMP and phospholipase A2- and phospholipase C-metabolites, Di Marzo, V., Galadari, S.H.I., Tippins, J.R., Morris, H.R., 1991, 10.1016/0024-3205(91)90011-Y
  • Prostaglandin 1,15-lactones of the F series from the nudibranch mollusc Tethys fimbria, Cimino, G., Crispino, A., Di Marzo, V., Spinella, A., Sodano, G., 1991
  • The effect of diterpenoidic diacylglycerols on tentacle regeneration in Hydra vulgaris, De Petrocellis, L., Di Marzo, V., Arcà, B., Gavagnin, M., Minei, R., Cimino, G., 1991, 10.1016/0742-8413(91)90047-W
  • Minor bioactive polyacetylenes from Petrosia ficiformis, Cimino, G., De Giulio, A., De Rosa, S., Di Marzo, V., 1990
  • Novel interactions between second messengers in rat basophilic leukaemia (RBL-1) cells, Galadari, S.H.I., Morris, H.R., Di Marzo, V., 1990
  • Oxytoxins, bioactive molecules produced by the marine opisthobranch mollusc Oxynoe olivacea from a diet-derived precursor, Cimino, G., Crispino, A., Di Marzo, V., Gavagnin, M., Ros, J.D., 1990, 10.1007/BF01939963
  • Structure-activity relationship of human calcitonin-gene-related peptide, Zaidi, M., Brain, S.D., Tippins, J.R., Di Marzo, V., Moonga, B.S., Chambers, T.J., Morris, H.R., MacIntyre, I., 1990
  • A novel amino acid substitution in the reactive site of a congenital variant antithrombin. Antithrombin Pescara, Arg393 to Pro, caused by CGT to CCT mutation, Lane, D.A., Erdjument, H., Thompson, E., Panico, M., Di Marzo, V., Morris, H.R., Leone, G., De Stefano, V., Thein, S.L., 1989
  • Antithrombin Chicago, amino acid substitution of arginine 393 to histidine, Erdjument, H., Lane, D.A., Panico, M., Di Marzo, V., Morris, H.R., Bauer, K., Rosenberg, R.D., 1989, 10.1016/0049-3848(89)90127-8
  • Antithrombin Sheffield: amino acid substitution at the reactive site (Arg393 to His) causing thrombosis, Lane, D.A., Erdjument, H., Flynn, A., Di Marzo, V., Panico, M., Morris, H.R., Greaves, M., Dolan, G., Preston, F.E., 1989
  • High molecular weight polyacetylenes from Petrosia ficiformis: Further structural analysis and biological activity, Cimino, G., De Giulio, A., De Rosa, S., Di Marzo, V., 1989, 10.1016/S0040-4039(00)99441-3
  • Neuropeptides and inflammatory mediators: bidirectional regulatory mechanisms, Di Marzo, V., Tippins, J.R., Morris, H.R., 1989, 10.1016/0165-6147(89)90198-3
  • The role of cyclic AMP in the inhibition of leukotriene biosynthesis by neuropeptides, Di Marzo, V., Tippins, J.R., Morris, H.R., 1989, 10.1016/0014-2999(89)90610-9
  • The synthesis, release and action of leukotrienes in the isolated, unstimulated, buffer-perfused rat heart, Garlick, P.B., Mashiter, G.D., Di Marzo, V., Tippins, J.R., Morris, H.R., Maisey, M.N., 1989, 10.1016/0022-2828(89)90688-3
  • Antithrombin Milano, single amino acid substitution at the reactive site, Arg393 to Cys, Erdjument, H., Lane, D.A., Ireland, H., Di Marzo, V., Panico, M., Morris, H.R., Tripodi, A., Mannucci, P.M., 1988
  • Bradykinin- and chemotactic peptide fMLP-stimulated leukotriene biosynthesis in rat lungs and its inhibition by vasoactive intestinal peptide, Di Marzo, V., Tippins, J.R., Morris, H.R., 1988
  • Leukotriene release by human fetal membranes, placenta and decidua in relation to parturition, Rees, M.C.P., Di Marzo, V., Bernal, A.L., Tippins, J.R., Morris, H.R., Turnbull, A.C., 1988
  • Neuropeptides and leukotriene biosynthesis: The effect of calcitonin, peptide histidine valine-42, helodermin, neuropeptide Y and galanin, Di Marzo, V., Tippins, J.R., Galadari, S.H.I., Morris, H.R., 1988, 10.1016/0143-4179(88)90071-6
  • Single amino acid substitutions in the reactive site of antithrombin leading to thrombosis. Congenital substitution of arginine 393 to cysteine in antithrombin Northwick Park and to histidine in antithrombin Glasgow, Erdjument, H., Lane, D.A., Panico, M., Di Marzo, V., Morris, H.R., 1988
  • Effect of vasoactive intestinal peptide and calcitonin gene-related peptide on leukotriene release from guinea pig and rat lung., Tippins, J.R., Di Marzo, V., Morris, H.R., 1987
  • Formation of a covalent disulfide-linked antithrombin-albumin complex by an antithrombin variant, antithrombin 'Northwick Park', Erdjument, H., Lane, D.A., Ireland, H., Panico, M., Di Marzo, V., Blench, I., Morris, H.R., 1987
  • Isolation, characterization, and pharmacological actions of peptide histidine valine 42, a novel prepro-vasoactive intestinal peptide-derived peptide, Yiangou, Y., Di Marzo, V., Spokes, R.A., Panico, M., Morris, H.R., Bloom, S.R., 1987
  • Leukotriene release by nonpregnant human endometrium and myometrium., Rees, M.C., Di Marzo, V., Tippins, J.R., Morris, H.R., Turnbull, A.C., 1987
  • Neuropeptides and leukotriene release: Effect of peptide histidine isoleucine and secretin in platelet activating factor-stimulated rat lung, Di Marzo, V., Tippins, J.R., Morris, H.R., 1987, 10.1016/0143-4179(87)90032-1
  • PAF-mediated leukotriene biosynthesis in lungs : Control by the neuropeptidergic system, Di Marzo, V., Tippins, J.R., Morris, H.R., 1987, 10.1016/0090-6980(87)90228-0
  • Platelet activating factor-mediated leukotriene biosynthesis in rat lungs: effect of prostaglandins E1 and F1a, Di Marzo, V., Tippins, J.R., Morris, H.R., 1987, 10.1016/S0006-291X(87)80199-7
  • Investigation of the structure/activity relationship of human calcitonin gene-related peptide (CGRP), Tippins, J.R., Di Marzo, V., Panico, M., Morris, H.R., MacIntyre, I., 1986, 10.1016/0006-291X(86)90392-X
  • RIA/chromatographic evidence for novel opioid peptide(s) in Squilla mantis ganglia, Palmisano, A., Marino, G., Di Marzo, V., Morris, H.R., Howlett, T.A., Tomlin, S., 1986, 10.1016/0143-4179(86)90022-3
  • The effect of vasoactive intestinal peptide and calcitonin gene-related peptide on peptidoleukotriene release from platelet activating factor stimulated rat lungs and ionophore stimulated guinea pig lungs, Di Marzo, V., Tippins, J.R., Morris, H.R., 1986
  • Native opioid-like peptides in Squilla mantis ganglia, Marino, G., Palmisano, A., Di Marzo, V., Melck, D., Miralto, A., 1985, 10.1016/0196-9781(85)90405-X
  • β-Endorphin in Neoroblastoma x Glioma hybrid cells, Di Marzo, V., Etienne, A., Marino, G., Morris, H.R., Palmisano, A., 1985, 10.1016/0143-4179(85)90130-1
  • Methionine-enkephalin presursor in neuroblastoma X glioma hybrid cells: In vivo and in vitro evidence, Di Marzo, V., Marino, G., Palmisano, A., 1984
  • A Designer Diet Induces Thermogenic Adipocytes via Raptor and Prolongs Healthy Lifespan, Maurizio Ragni, Chiara Ruocco, Fabio Rossi, Pierluigi Carullo, Veronica Ghini, Fabiana Piscitelli, Adele Cutignano, Emiliano Manzo, Rafael Maciel Ioris, Franck Bontems, Laura Tedesco, Carolina Greco, Annachiara Pino, Ilenia Severi, Dianxin Liu, Ryan P. Ceddia, Luisa Ponzoni, Leonardo Tenori, Lisa Rizzetto, Matthias U. Scholz, Kieran Tuohy, Francesco Bifari, Vincenzo Di Marzo, Claudio Luchinat, Michele O. Carruba, Saverio Cinti, Ilaria Decimo, Gianluigi Condorelli, Roberto Coppari, Sheila Collins, Alessandra Valerio, Enzo Nisoli, SSRN Electronic Journal, 1911, 10.2139/ssrn.3435269

Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2009
  • Guillaume Quang Henri Nguyen - Post-doctorat - En cours
  • Sébastien Lacroix - Post-doctorat - En cours
  • Sara Anunciacao Braga Guebara - Post-doctorat - En cours
  • Fredy Alexander Guevara Agudelo - Doctorat - En cours
  • Jyoti Sihag - Post-doctorat - En cours
  • Nayudu Nallabelli - Doctorat - En cours
  • Niokhor Dione - Post-doctorat - En cours
  • Giada Giorgini - Doctorat - En cours
  • Ludovic Jacques - Maitrîse avec mémoire - En cours
  • Rim Ben Necib - Doctorat - En cours
  • Francesco Tinto - Post-doctorat - En cours
  • Nicola Forte - Post-doctorat - En cours
  • Armita Abolghasemi - Doctorat - 2020/05
  • Frédéric Bégin - Maitrîse avec mémoire - 2021/01

Encadrement d'étudiant(e)s pour les programmes suivants :

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*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.

Direction et personnes-ressources

Vice-décanat à la recherche et aux études supérieures
Pavillon Ferdinand-Vandry
Université Laval
1050, avenue de la Médecine,  local 4645
Québec, Québec G1V 0A6
Canada

Renseignements - Secrétariat :
vdres@fmed.ulaval.ca

Jacques Simard
Vice-doyen à la recherche et aux études supérieures
vice-doyen.recherche-et-etudes-superieures@fmed.ulaval.ca

Louise Laperrière
Adjointe au vice-doyen à la recherche et aux études supérieures
louise.laperriere@fmed.ulaval.ca 

Volet recherche
Gestion financière
Volet études aux cycles supérieurs