Découvrez nos professeurs et professeures!

Patrick Couture

Médecin clinicien enseignant titulaire

Patrick Couture
Centre de recherche en sciences et technologie du lait
Centre de recherche du CHU de Québec - Université Laval
Nutrition, santé et société (NUTRISS)
Partager la fiche :

Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Santé cardiovasculaire, respiratoire et métabolisme

Domaines et intérêts de recherche du (de la) professeur(e) :

Santé circulatoire et respiratoire
  • Athérosclérose

Projets de recherche

  • Unravelling the impact of diet on cardiovascular health in heterozygous familial hypercholesterolemia: a metabolomic approach - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2021-10-01 au 2025-09-30
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.3 - Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.1 - Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
  • Mediterranean diet and physical activity: is the whole better than the sum of each part ? Clinical and mechanistic perspectives - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2018-04-01 au 2024-03-31
  • Institut sur la nutrition et les aliments fonctionnels (INAF) - Institut national de recherche scientifique (INRS), Fonds de recherche du Québec - Nature et technologies, Université Laval - Fonds internes, Université McGill, Université du Québec à Rimouski, Université de Sherbrooke - Regroupements stratégiques NT, co-chercheur - 2017-04-01 au 2024-03-31
  • Canada-Wide Human nutrition trialists' network - Instituts de recherche en santé du Canada - Subventions de recherche programmatique sur l’alimentation et la santé, University of Toronto, co-chercheur - 2014-06-01 au 2023-03-31
  • Analysis of specific hepatic gene expression in patients with a clinical diagnosis of non-alcoholic fatty liver disease – A pilot study - CHU de Québec – Université Laval – CHUL - Développement de la recherche (FC), chercheur principal - 2022-03-24 au 2023-03-24
  • Differential effects of saturated and monounsaturated fatty acids on chylomicron secretion and the expression of key genes that regulate intestinal lipid metabolism in insulin-resistant subjects - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2019-04-01 au 2022-03-31
  • Indices de qualité nutritionnelle et calcification des artères coronaires dans une cohorte d'individus avec hypercholestérolémie familiale hétérozygote - Fonds de recherche du Québec - Nature et technologies - Projet subsidiaire d'un regroupement stratégique (pour fins de gestion au VRRCI), co-chercheur - 2021-02-02 au 2022-03-31
  • Plant-based dietary patterns and coronary artery calcification in adults with heterozygous familial hypercholesterolemia - The Canadian Foundation for Dietetic Research, co-chercheur - 2021-04-01 au 2022-03-31
  • Qualité nutritionnelle des aliments et déterminants de l'adhésion aux saines habitudes alimentaires - Ministère de l'Enseignement supérieur, de la Recherche, de la Science, Fondation Canadienne pour l'innovation (La) - Fonds d'innovation (FI), co-chercheur - 2015-12-01 au 2021-09-30
  • Effet des acides gras saturés et monoinsaturés sur la sécrétion des chylomicrons et l'expression des gènes et des protéines qui régulent le métabolisme intestinal des lipides - CHU de Québec – Université Laval – CHUL - Développement de la recherche (FC), chercheur principal - 2020-08-26 au 2021-08-31
  • The effect of an enhanced dietary portfolio flus exercise on cardiovascular risk in high risk individuals - Instituts de recherche en santé du Canada - Subvention de fonctionnement, University of Toronto, co-chercheur - 2013-10-01 au 2021-03-31
  • Réunions scientifiques de médecine du CHUL - Amgen Canada Inc., chercheur principal - 2015-12-08 au 2021-03-31

Publications

  • Lomitapide for treatment of homozygous familial hypercholesterolemia: The Québec experience, Sumayah Aljenedil, Latifah Alothman, Alexandre M. Bélanger, Leslie Brown, Zubin Lahijanian, Jean Bergeron, Patrick Couture, Alexis Baass, Isabelle Ruel, Diane Brisson, Etienne Khoury, Daniel Gaudet, Jacques Genest, Atherosclerosis, 2020, 10.1016/j.atherosclerosis.2020.07.028
  • Common Variants in Lipid Metabolism–Related Genes Associate with Fat Mass Changes in Response to Dietary Monounsaturated Fatty Acids in Adults with Abdominal Obesity, Shatha S Hammad, Peter Eck, Jyoti Sihag, Xiang Chen, Philip W Connelly, Benoît Lamarche, Patrick Couture, Valérie Guay, Julie Maltais-Giguère, Sheila G West, Penny M Kris-Etherton, Kate J Bowen, David J A Jenkins, Carla G Taylor, Danielle Perera, Angela Wilson, Sandra Castillo, Peter Zahradka, Peter J H Jones, The Journal of Nutrition, 2019, 10.1093/jn/nxz136
  • Comparing the serum TAG response to high-dose supplementation of either DHA or EPA among individuals with increased cardiovascular risk: The ComparED study, Allaire, J., Vors, C., Harris, W.S., Jackson, K.H., Tchernof, A., Couture, P., Lamarche, B., British Journal of Nutrition, 2019, 10.1017/S0007114519000552
  • Correlates of the difference in plasma carotenoid concentrations between men and women, Allore, T., Lemieux, S., Vohl, M.-C., Couture, P., Lamarche, B., Couillard, C., British Journal of Nutrition, 2019, 10.1017/S0007114518003045
  • Development and validation of a Brief Diet Quality Assessment Tool in the French-speaking adults from Quebec, Lafrenière, J., Harrison, S., Laurin, D., Brisson, C., Talbot, D., Couture, P., Lemieux, S., Lamarche, B., International Journal of Behavioral Nutrition and Physical Activity, 2019, 10.1186/s12966-019-0821-6
  • Diets enriched with conventional or high-oleic acid canola oils lower atherogenic lipids and lipoproteins compared to a diet with a western fatty acid profile in adults with central adiposity, Bowen, K.J., Kris-Etherton, P.M., West, S.G., Fleming, J.A., Connelly, P.W., Lamarche, B., Couture, P., Jenkins, D.J.A., Taylor, C.G., Zahradka, P., Hammad, S.S., Sihag, J., Chen, X., Guay, V., Maltais-Giguère, J., Perera, D., Wilson, A., Juan, S.C.S., Rempel, J., Jones, P.J.H., Journal of Nutrition, 2019, 10.1093/jn/nxy307
  • Fine mapping of genome-wide association study signals to identify genetic markers of the plasma triglyceride response to an omega-3 fatty acid supplementation, Marcotte, B.V., Guénard, F., Lemieux, S., Couture, P., Rudkowska, I., Calder, P.C., Minihane, A.M., Vohl, M.-C., American Journal of Clinical Nutrition, 2019, 10.1093/ajcn/nqy298
  • Lipoprotein(a), Oxidized Phospholipids, and Aortic Valve Microcalcification Assessed by 18F-Sodium Fluoride Positron Emission Tomography and Computed Tomography, Després, A.-A., Perrot, N., Poulin, A., Tastet, L., Shen, M., Chen, H.Y., Bourgeois, R., Trottier, M., Tessier, M., Guimond, J., Nadeau, M., Engert, J.C., Thériault, S., Bossé, Y., Witztum, J.L., Couture, P., Mathieu, P., Dweck, M.R., Tsimikas, S., Thanassoulis, G., Pibarot, P., Clavel, M.-A., Arsenault, B.J., CJC Open, 2019, 10.1016/j.cjco.2019.03.004
  • The Lifelong Burden of Homozygous Familial Hypercholesterolemia, Banerjee, A., Alothman, L., Couture, P., Bergeron, J., Bélanger, A.M., Ruel, I., Genest, J., Canadian Journal of Cardiology, 2019, 10.1016/j.cjca.2019.06.009
  • A common variant in ARHGEF10 alters delta-6 desaturase activity and influence susceptibility to hypertriglyceridemia, de Toro-Martín, J., Guénard, F., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C., Journal of Clinical Lipidology, 2018, 10.1016/j.jacl.2017.10.020
  • Assessing the impact of the diet on cardiometabolic outcomes: are multiple measurements post-intervention necessary?, Allaire, J., Talbot, D., Couture, P., Tchernof, A., Jones, P.J.H., Kris-Etherton, P., West, S.G., Connelly, P.W., Jenkins, D.J.A., Lamarche, B., European Journal of Clinical Nutrition, 2018, 10.1038/s41430-018-0257-0
  • Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia: Update 2018, Brunham, L.R., Ruel, I., Aljenedil, S., Rivière, J.-B., Baass, A., Tu, J.V., Mancini, G.B.J., Raggi, P., Gupta, M., Couture, P., Pearson, G.J., Bergeron, J., Francis, G.A., McCrindle, B.W., Morrison, K., St-Pierre, J., Henderson, M., Hegele, R.A., Genest, J., Goguen, J., Gaudet, D., Paré, G., Romney, J., Ransom, T., Bernard, S., Katz, P., Joy, T.R., Bewick, D., Brophy, J., Canadian Journal of Cardiology, 2018, 10.1016/j.cjca.2018.09.005
  • Comparing interviewer-administered and web- based food frequency questionnaires to predict energy requirements in adults, Brassard, D., Lemieux, S., Charest, A., Lapointe, A., Couture, P., Labonté, M.-È., Lamarche, B., Nutrients, 2018, 10.3390/nu10091292
  • Diets low in saturated fat with different unsaturated fatty acid profiles similarly increase serum-mediated cholesterol efflux from THP-1 macrophages in a population with or at risk for metabolic syndrome: The Canola Oil Multicenter Intervention Trial, Liu, X., Garban, J., Jones, P.J., Heuvel, J.V., Lamarche, B., Jenkins, D.J., Connelly, P.W., Couture, P., Pu, S., Fleming, J.A., West, S.G., Kris-Etherton, P.M., Journal of Nutrition, 2018, 10.1093/jn/nxy040
  • Differential associations between plasma concentrations of insulin and glucose and intestinal expression of key genes involved in chylomicron metabolism, Drouin-Chartier, J.-P., Tremblay, A.J., Lemelin, V., Lamarche, B., Couture, P., American Journal of Physiology - Gastrointestinal and Liver Physiology, 2018, 10.1152/ajpgi.00108.2018
  • Familial hypercholesterolemia in Canada: Initial results from the FH Canada national registry, Brunham, L.R., Ruel, I., Khoury, E., Hegele, R.A., Couture, P., Bergeron, J., Baass, A., Dufour, R., Francis, G.A., Cermakova, L., Mancini, G.B.J., Brophy, J.M., Brisson, D., Gaudet, D., Genest, J., Atherosclerosis, 2018, 10.1016/j.atherosclerosis.2018.05.040
  • High serum triglyceride concentrations in patients with homozygous familial hypercholesterolemia attenuate the efficacy of lipoprotein apheresis by dextran sulfate adsorption, Drouin-Chartier, J.-P., Tremblay, A.J., Bergeron, J., Lamarche, B., Couture, P., Atherosclerosis, 2018, 10.1016/j.atherosclerosis.2018.01.005
  • High-dose DHA has more profound effects on LDL-related features than high-dose EPA: The ComparED study, Allaire, J., Vors, C., Tremblay, A.J., Marin, J., Charest, A., Tchernof, A., Couture, P., Lamarche, B., Journal of Clinical Endocrinology and Metabolism, 2018, 10.1210/jc.2017-02745
  • Hypertriglyceridemia and cardiovascular risk: a cautionary note about metabolic confounding, Sniderman, A.D., Couture, P., Martin, S.S., DeGraaf, J., Lawler, P.R., Cromwell, W.C., Wilkins, J.T., Thanassoulis, G., Journal of Lipid Research, 2018, 10.1194/jlr.R082271
  • Impact of lipoprotein apheresis with dextran-sulfate adsorption on the expression of genes involved in cardiovascular health in the blood of patients with homozygous familial hypercholesterolemia, Drouin-Chartier, J.-P., Tremblay, A.J., Bergeron, J., Laflamme, N., Lamarche, B., Couture, P., Journal of Clinical Apheresis, 2018, 10.1002/jca.21569
  • Imputation of baseline LDL cholesterol concentration in patients with familial hypercholesterolemia on statins or ezetimibe, Ruel, I., Aljenedil, S., Sadri, I., De Varennes, É., Hegele, R.A., Couture, P., Bergeron, J., Wanneh, E., Baass, A., Dufour, R., Gaudet, D., Brisson, D., Brunham, L.R., Francis, G.A., Cermakova, L., Brophy, J.M., Ryomoto, A., John Mancini, G.B., Genest, J., Clinical Chemistry, 2018, 10.1373/clinchem.2017.279422
  • Plasma PCSK9 correlates with apoB-48-containing triglyceride-rich lipoprotein production in men with insulin resistance, Drouin-Chartier, J.-P., Tremblay, A.J., Hogue, J.-C., Lemelin, V., Lamarche, B., Couture, P., Journal of Lipid Research, 2018, 10.1194/jlr.M086264
  • Saturated fats from butter but not from cheese increase HDL-Mediated cholesterol efflux capacity from J774 macrophages in men and women with abdominal obesity, Brassard, D., Arsenault, B.J., Boyer, M., Bernic, D., Tessier-Grenier, M., Talbot, D., Tremblay, A., Levy, E., Asztalos, B., Jones, P.J.H., Couture, P., Lamarche, B., Journal of Nutrition, 2018, 10.1093/jn/nxy014
  • Simplified Canadian Definition for Familial Hypercholesterolemia, Ruel, I., Brisson, D., Aljenedil, S., Awan, Z., Baass, A., Bélanger, A., Bergeron, J., Bewick, D., Brophy, J.M., Brunham, L.R., Couture, P., Dufour, R., Francis, G.A., Frohlich, J., Gagné, C., Gaudet, D., Grégoire, J.C., Gupta, M., Hegele, R.A., Mancini, G.B.J., McCrindle, B.W., Pang, J., Raggi, P., Tu, J.V., Watts, G.F., Genest, J., Canadian Journal of Cardiology, 2018, 10.1016/j.cjca.2018.05.015
  • Substitution of dietary ω-6 polyunsaturated fatty acids for saturated fatty acids decreases LDL apolipoprotein B-100 production rate in men with dyslipidemia associated with insulin resistance: A randomized controlled trial, Drouin-Chartier, J.-P., Tremblay, A.J., Lépine, M.-C., Lemelin, V., Lamarche, B., Couture, P., American Journal of Clinical Nutrition, 2018, 10.1093/ajcn/nqx013
  • Supplementation with resveratrol and curcumin does not affect the inflammatory response to a high-fat meal in older adults with abdominal obesity: A randomized, placebo-controlled crossover trial, Vors, C., Couillard, C., Paradis, M.-E., Gigleux, I., Marin, J., Vohl, M.-C., Couture, P., Lamarche, B., Journal of Nutrition, 2018, 10.1093/jn/nxx072
  • The combination of single nucleotide polymorphisms rs6720173 (ABCG5), rs3808607 (CYP7A1), and rs760241 (DHCR7) is associated with differing serum cholesterol responses to dairy consumption, Abdullah, M.M.H., Eck, P.K., Couture, P., Lamarche, B., Jones, P.J.H., Applied Physiology, Nutrition and Metabolism, 2018, 10.1139/apnm-2018-0085
  • The spectrum of type III hyperlipoproteinemia, Sniderman, A.D., de Graaf, J., Thanassoulis, G., Tremblay, A.J., Martin, S.S., Couture, P., Journal of Clinical Lipidology, 2018, 10.1016/j.jacl.2018.09.006
  • C-reactive protein levels are inversely correlated with the apolipoprotein B-48-containing triglyceride-rich lipoprotein production rate in insulin resistant men, Drouin-Chartier, J.-P., Tremblay, A.J., Hogue, J.-C., Leclerc, M., Labonté, M.-È., Marin, J., Lamarche, B., Couture, P., Metabolism: Clinical and Experimental, 2017, 10.1016/j.metabol.2016.11.019
  • Changes in high-density lipoprotein-carried miRNA contribution to the plasmatic pool after consumption of dietary trans fat in healthy men, Desgagné, V., Guérin, R., Guay, S.-P., Corbin, F., Couture, P., Lamarche, B., Bouchard, L., Epigenomics, 2017, 10.2217/epi-2016-0177
  • Comparison of the impact of SFAs from cheese and butter on cardiometabolic risk factors: A randomized controlled trial, Brassard, D., Tessier-Grenier, M., Allaire, J., Rajendiran, E., She, Y., Ramprasath, V., Gigleux, I., Talbot, D., Levy, E., Tremblay, A., Jones, P.J.H., Couture, P., Lamarche, B., American Journal of Clinical Nutrition, 2017, 10.3945/ajcn.116.150300
  • Differential impact of the cheese matrix on the postprandial lipid response: A randomized, crossover, controlled trial, Drouin-Chartier, J.-P., Tremblay, A.J., Maltais-Giguère, J., Charest, A., Guinot, L., Rioux, L.-E., Labrie, S., Britten, M., Lamarche, B., Turgeon, S.L., Couture, P., American Journal of Clinical Nutrition, 2017, 10.3945/ajcn.117.165027
  • Does lifestyle contribute to disease severity in patients with inherited lipid disorders?, Arsenault, B.J., Perrot, N., Couture, P., Current Opinion in Lipidology, 2017, 10.1097/MOL.0000000000000387
  • Effects of the mediterranean diet before and after weight loss on eating behavioral traits in men with metabolic syndrome, Carbonneau, É., Royer, M.-M., Richard, C., Couture, P., Desroches, S., Lemieux, S., Lamarche, B., Nutrients, 2017, 10.3390/nu9030305
  • Epigenetic changes in blood leukocytes following an omega-3 fatty acid supplementation, Tremblay, B.L., Guénard, F., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C., Clinical Epigenetics, 2017, 10.1186/s13148-017-0345-3
  • Genome-wide association study of dietary pattern scores, Guénard, F., Bouchard-Mercier, A., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C., Nutrients, 2017, 10.3390/nu9070649
  • Inflammatory gene expression in whole blood cells after EPA vs. DHA supplementation: Results from the ComparED study, Vors, C., Allaire, J., Marin, J., Lépine, M.-C., Charest, A., Tchernof, A., Couture, P., Lamarche, B., Atherosclerosis, 2017, 10.1016/j.atherosclerosis.2017.01.025
  • LDL particle number and size and cardiovascular risk: Anything new under the sun?, Allaire, J., Vors, C., Couture, P., Lamarche, B., Current Opinion in Lipidology, 2017, 10.1097/MOL.0000000000000419
  • Lifestyle recommendations for the prevention and management of metabolic syndrome: An international panel recommendation, Pérez-Martínez, P., Mikhailidis, D.P., Athyros, V.G., Bullo, M., Couture, P., Covas, M.I., de Koning, L., Delgado-Lista, J., Díaz-López, A., Drevon, C.A., Estruch, R., Esposito, K., Fitó, M., Garaulet, M., Giugliano, D., García-Ríos, A., Katsiki, N., Kolovou, G., Lamarche, B., Maiorino, M.I., Mena-Sánchez, G., Muñoz-Garach, A., Nikolic, D., Ordovás, J.M., Pérez-Jiménez, F., Rizzo, M., Salas-Salvadó, J., Schrö der, H., Tinahones, F.J., de la Torre, R., van Ommen, B., Wopereis, S., Ros, E., López-Miranda, J., Nutrition Reviews, 2017, 10.1093/nutrit/nux014
  • Lipid Metabolism and Emerging Targets for Lipid-Lowering Therapy, Gaudet, D., Drouin-Chartier, J.-P., Couture, P., Canadian Journal of Cardiology, 2017, 10.1016/j.cjca.2016.12.019
  • Long-term treatment with evolocumab added to conventional drug therapy, with or without apheresis, in patients with homozygous familial hypercholesterolaemia: an interim subset analysis of the open-label TAUSSIG study, Raal, F.J., Hovingh, G.K., Blom, D., Santos, R.D., Harada-Shiba, M., Bruckert, E., Couture, P., Soran, H., Watts, G.F., Kurtz, C., Honarpour, N., Tang, L., Kasichayanula, S., Wasserman, S.M., Stein, E.A., The Lancet Diabetes and Endocrinology, 2017, 10.1016/S2213-8587(17)30044-X
  • Plasma triglyceride levels may be modulated by gene expression of IQCJ, NXPH1, PHF17 and MYB in humans, Marcotte, B.V., Guénard, F., Cormier, H., Lemieux, S., Couture, P., Rudkowska, I., Vohl, M.-C., International Journal of Molecular Sciences, 2017, 10.3390/ijms18020257
  • Polymorphisms in FFAR4 (GPR120) gene modulate insulin levels and sensitivity after fish oil supplementation, Marcotte, B.V., Cormier, H., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C., Journal of Personalized Medicine, 2017, 10.3390/jpm7040015
  • Supplementation with high-dose docosahexaenoic acid increases the Omega-3 Index more than high-dose eicosapentaenoic acid, Allaire, J., Harris, W.S., Vors, C., Charest, A., Marin, J., Jackson, K.H., Tchernof, A., Couture, P., Lamarche, B., Prostaglandins Leukotrienes and Essential Fatty Acids, 2017, 10.1016/j.plefa.2017.03.008
  • The elevation of plasma concentrations of apoB-48-containing lipoproteins in familial hypercholesterolemia is independent of PCSK9 levels, Drouin-Chartier, J.-P., Hogue, J.-C., Tremblay, A.J., Bergeron, J., Lamarche, B., Couture, P., Lipids in Health and Disease, 2017, 10.1186/s12944-017-0502-x
  • The low-density lipoprotein receptor genotype is a significant determinant of the rebound in low-density lipoprotein cholesterol concentration after lipoprotein apheresis among patients with homozygous familial hypercholesterolemia, Drouin-Chartier, J.-P., Tremblay, A.J., Bergeron, J., Lamarche, B., Couture, P., Circulation, 2017, 10.1161/CIRCULATIONAHA.117.029435
  • 2016 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult, Anderson, T.J., Grégoire, J., Pearson, G.J., Barry, A.R., Couture, P., Dawes, M., Francis, G.A., Genest, J., Grover, S., Gupta, M., Hegele, R.A., Lau, D.C., Leiter, L.A., Lonn, E., Mancini, G.B.J., McPherson, R., Ngui, D., Poirier, P., Sievenpiper, J.L., Stone, J.A., Thanassoulis, G., Ward, R., Canadian Journal of Cardiology, 2016, 10.1016/j.cjca.2016.07.510
  • A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: The Comparing EPA to DHA (ComparED) Study, Allaire, J., Couture, P., Leclerc, M., Charest, A., Marin, J., Lépine, M.-C., Talbot, D., Tchernof, A., Lamarche, B., American Journal of Clinical Nutrition, 2016, 10.3945/ajcn.116.131896
  • Carotenoids as biomarkers of fruit and vegetable intake in men and women, Couillard, C., Lemieux, S., Vohl, M.-C., Couture, P., Lamarche, B., British Journal of Nutrition, 2016, 10.1017/S0007114516003056
  • Common variants in cholesterol synthesis- and transport-related genes associate with circulating cholesterol responses to intakes of conventional dairy products in healthy individuals, Abdullah, M.M.H., Cyr, A., Lépine, M.-C., Eck, P.K., Couture, P., Lamarche, B., Jones, P.J.H., Journal of Nutrition, 2016, 10.3945/jn.115.222208
  • Comparison of two low-density lipoprotein apheresis systems in patients with homozygous familial hypercholesterolemia, Drouin-Chartier, J.-P., Tremblay, A.J., Bergeron, J., Pelletier, M., Laflamme, N., Lamarche, B., Couture, P., Journal of Clinical Apheresis, 2016, 10.1002/jca.21406
  • Comprehensive review of the impact of dairy foods and dairy fat on cardiometabolic risk, Drouin-Chartier, J.-P., Côté, J.A., Labonté, M., Brassard, D., Tessier-Grenier, M., Desroches, S., Couture, P., Lamarche, B., Advances in Nutrition, 2016, 10.3945/an.115.011619
  • Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity, Liu, X., Kris-Etherton, P.M., West, S.G., Lamarche, B., Jenkins, D.J.A., Fleming, J.A., McCrea, C.E., Pu, S., Couture, P., Connelly, P.W., Jones, P.J.H., Obesity, 2016, 10.1002/oby.21584
  • Expression and sequence variants of inflammatory genes; Effects on plasma inflammation biomarkers following a 6-week supplementation with fish oil, Cormier, H., Rudkowska, I., Lemieux, S., Couture, P., Voh, M.-C., International Journal of Molecular Sciences, 2016, 10.3390/ijms17030375
  • Ezetimibe increases intestinal expression of the LDL receptor gene in dyslipidaemic men with insulin resistance, Drouin-Chartier, J.-P., Tremblay, A.J., Lemelin, V., Lépine, M.-C., Lamarche, B., Couture, P., Diabetes, Obesity and Metabolism, 2016, 10.1111/dom.12749
  • High-density lipoprotein subpopulation profiles in lipoprotein lipase and hepatic lipase deficiency, Tani, M., Horvath, K.V., Lamarche, B., Couture, P., Burnett, J.R., Schaefer, E.J., Asztalos, B.F., Atherosclerosis, 2016, 10.1016/j.atherosclerosis.2016.08.014
  • N-3 polyunsaturated fatty acid supplementation has no effect on postprandial triglyceride-rich lipoprotein kinetics in men with type 2 diabetes, Tremblay, A.J., Lamarche, B., Hogue, J.-C., Couture, P., Journal of Diabetes Research, 2016, 10.1155/2016/2909210
  • Novel Genetic Loci Associated with the Plasma Triglyceride Response to an Omega-3 Fatty Acid Supplementation, Vallée Marcotte, B., Cormier, H., Guénard, F., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C., Journal of Nutrigenetics and Nutrigenomics, 2016, 10.1159/000446024
  • Systematic review of the association between dairy product consumption and risk of cardiovascular-related clinical outcomes, Drouin-Chartier, J.-P., Brassard, D., Tessier-Grenier, M., Côté, J.A., Labonté, M., Desroches, S., Couture, P., Lamarche, B., Advances in Nutrition, 2016, 10.3945/an.115.011403
  • Variations in HDL-carried miR-223 and miR-135a concentrations after consumption of dietary trans fat are associated with changes in blood lipid and inflammatory markers in healthy men - an exploratory study, Desgagné, V., Guay, S.-P., Guérin, R., Corbin, F., Couture, P., Lamarche, B., Bouchard, L., Epigenetics, 2016, 10.1080/15592294.2016.1176816
  • ApoB in clinical care, De Graaf, J., Couture, P., Sniderman, A.D., ApoB in Clinical Care, 2015, 10.1007/978-90-368-0980-1
  • Association between polymorphisms in phospholipase A2 genes and the plasma triglyceride response to an n-3 PUFA supplementation: A clinical trial, Tremblay, B.L., Cormier, H., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C., Lipids in Health and Disease, 2015, 10.1186/s12944-015-0009-2
  • Dietary fatty acids, dietary patterns, and lipoprotein metabolism, Lamarche, B., Couture, P., Current Opinion in Lipidology, 2015, 10.1097/MOL.0000000000000139
  • Docosahexaenoic acid-enriched canola oil increases adiponectin concentrations: A randomized crossover controlled intervention trial, Baril-Gravel, L., Labonté, M.-E., Couture, P., Vohl, M.-C., Charest, A., Guay, V., Jenkins, D.A., Connelly, P.W., West, S., Kris-Etherton, P.M., Jones, P.J., Fleming, J.A., Lamarche, B., Nutrition, Metabolism and Cardiovascular Diseases, 2015, 10.1016/j.numecd.2014.08.003
  • Evaluation of iTRAQ and SWATH-MS for the quantification of proteins associated with insulin resistance in human duodenal biopsy samples, Bourassa, S., Fournier, F., Nehmé, B., Kelly, I., Tremblay, A., Lemelin, V., Lamarche, B., Couture, P., Droit, A., PLoS ONE, 2015, 10.1371/journal.pone.0125934
  • High-oleic canola oil consumption enriches LDL particle cholesteryl oleate content and reduces LDL proteoglycan binding in humans, Jones, P.J.H., MacKay, D.S., Senanayake, V.K., Pu, S., Jenkins, D.J.A., Connelly, P.W., Lamarche, B., Couture, P., Kris-Etherton, P.M., West, S.G., Liu, X., Fleming, J.A., Hantgan, R.R., Rudel, L.L., Atherosclerosis, 2015, 10.1016/j.atherosclerosis.2014.12.010
  • Impact of milk consumption on cardiometabolic risk in postmenopausal women with abdominal obesity, Drouin-Chartier, J.-P., Gagnon, J., Labonté, M.-È., Desroches, S., Charest, A., Grenier, G., Dodin, S., Lemieux, S., Couture, P., Lamarche, B., Nutrition Journal, 2015, 10.1186/1475-2891-14-12
  • Impact of systemic enzyme supplementation on low-grade inflammation in humans, Paradis, M.-E., Couture, P., Gigleux, I., Marin, J., Vohl, M.-C., Lamarche, B., PharmaNutrition, 2015, 10.1016/j.phanu.2015.04.004
  • Modulation of C-reactive protein and plasma omega-6 fatty acid levels by phospholipase A2 gene polymorphisms following a 6-week supplementation with fish oil, Tremblay, B.L., Rudkowska, I., Couture, P., Lemieux, S., Julien, P., Vohl, M.C., Prostaglandins Leukotrienes and Essential Fatty Acids, 2015, 10.1016/j.plefa.2015.10.002
  • Recommended dairy product intake modulates circulating fatty acid profile in healthy adults: A multi-centre cross-over study, Abdullah, M.M.H., Cyr, A., Lépine, M.-C., Labonté, M.-È., Couture, P., Jones, P.J.H., Lamarche, B., British Journal of Nutrition, 2015, 10.1017/S0007114514003894
  • The contribution of PCSK9 levels to the phenotypic severity of familial hypercholesterolemia is independent of LDL receptor genotype, Drouin-Chartier, J.-P., Tremblay, A.J., Hogue, J.-C., Ooi, T.C., Lamarche, B., Couture, P., Metabolism: Clinical and Experimental, 2015, 10.1016/j.metabol.2015.08.007
  • The effect of a dietary portfolio compared to a DASH-type diet on blood pressure, Jenkins, D.J.A., Jones, P.J., Frohlich, J., Lamarche, B., Ireland, C., Nishi, S.K., Srichaikul, K., Galange, P., Pellini, C., Faulkner, D., de Souza, R.J., Sievenpiper, J.L., Mirrahimi, A., Jayalath, V.H., Augustin, L.S., Bashyam, B., Leiter, L.A., Josse, R., Couture, P., Ramprasath, V., Kendall, C.W.C., Nutrition, Metabolism and Cardiovascular Diseases, 2015, 10.1016/j.numecd.2015.08.006
  • An interaction effect between glucokinase gene variation and carbohydrate intakes modulates the plasma triglyceride response to a fish oil supplementation, Bouchard-Mercier, A., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C., Genes and Nutrition, 2014, 10.1007/s12263-014-0395-5
  • Are the ACC/AHA Guidelines on the Treatment of Blood Cholesterol a Game Changer? A Perspective From the Canadian Cardiovascular Society Dyslipidemia Panel, Anderson, T.J., Grégoire, J., Hegele, R.A., Couture, P., Mancini, G.B.J., McPherson, R., Francis, G.A., Poirier, P., Lau, D.C., Grover, S., Genest, J., Carpentier, A.C., Dufour, R., Gupta, M., Ward, R., Leiter, L.A., Lonn, E., Ng, D.S., Pearson, G.J., Yates, G.M., Stone, J.A., Ur, E., Canadian Journal of Cardiology, 2014, 10.1016/j.cjca.2014.01.009
  • Association of red blood cell n-3 polyunsaturated fatty acids with plasma inflammatory biomarkers among the Quebec Cree population, Labonté, M.-È., Dewailly, É., Lucas, M., Couture, P., Lamarche, B., European Journal of Clinical Nutrition, 2014, 10.1038/ejcn.2014.125
  • Associations between dairy intake and metabolic risk parameters in a healthy french-Canadian population, Da Silva, M.S., Julien, P., Couture, P., Lemieux, S., Vohl, M.-C., Rudkowska, I., Applied Physiology, Nutrition and Metabolism, 2014, 10.1139/apnm-2014-0154
  • Calculation of LDL apoB, Sniderman, A.D., Tremblay, A.J., De Graaf, J., Couture, P., Atherosclerosis, 2014, 10.1016/j.atherosclerosis.2014.03.012
  • Canadian Cardiovascular Society Position Statement onFamilial Hypercholesterolemia, Genest, J., Hegele, R.A., Bergeron, J., Brophy, J., Carpentier, A., Couture, P., Davignon, J., Dufour, R., Frohlich, J., Gaudet, D., Gupta, M., Krisnamoorthy, P., Mancini, J., McCrindle, B., Raggi, P., Ruel, I., St-Pierre, J., Canadian Journal of Cardiology, 2014, 10.1016/j.cjca.2014.09.028
  • Cardiometabolic risk factors are influenced by Stearoyl-CoA Desaturase (SCD) -1 gene polymorphisms and n-3 polyunsaturated fatty acid supplementation, Rudkowska, I., Julien, P., Couture, P., Lemieux, S., Tchernof, A., Barbier, O., Vohl, M.-C., Molecular Nutrition and Food Research, 2014, 10.1002/mnfr.201300426
  • Consumption of a dietary portfolio of cholesterol lowering foods improves blood lipids without affecting concentrations of fat soluble compounds, Ramprasath, V.R., Jenkins, D.J., Lamarche, B., Kendall, C.W., Faulkner, D., Cermakova, L., Couture, P., Ireland, C., Abdulnour, S., Patel, D., Bashyam, B., Srichaikul, K., de Souza, R.J., Vidgen, E., Josse, R.G., Leiter, L.A., Connelly, P.W., Frohlich, J., Jones, P.J., Nutrition journal, 2014, 10.1186/1475-2891-13-101
  • Dairy product consumption has no impact on biomarkers of inflammation among men and women with low-grade systemic inflammation, Labontè, M.-E., Cyr, A., Abdullah, M.M., Lépine, M.-C., Vohl, M.-C., Jones, P., Couture, P., Lamarche, B., Journal of Nutrition, 2014, 10.3945/jn.114.200576
  • Dha-enriched high-oleic acid canola oil improves lipid profile and lowers predicted cardiovascular disease risk in the canola oil multicenter randomized controlled trial, Jones, P.J.H., Senanayake, V.K., Pu, S., Jenkins, D.J.A., Connelly, P.W., Lamarche, B., Couture, P., Charest, A., Baril-Gravel, L., West, S.G., Liu, X., Fleming, J.A., McCrea, C.E., Kris-Etherton, P.M., American Journal of Clinical Nutrition, 2014, 10.3945/ajcn.113.081133
  • Dietary medium-chain triglyceride supplementation has no effect on apolipoprotein B-48 and apolipoprotein B-100 kinetics in insulin-resistant men, Tremblay, A.J., Lamarche, B., Labonté, M.-E., Lépine, M.-C., Lemelin, V., Couture, P., American Journal of Clinical Nutrition, 2014, 10.3945/ajcn.113.068767
  • Effect of an isoenergetic traditional mediterranean diet on the high-density lipoprotein proteome in men with the metabolic syndrome, Richard, C., Couture, P., Desroches, S., Nehmé, B., Bourassa, S., Droit, A., Lamarche, B., Journal of Nutrigenetics and Nutrigenomics, 2014, 10.1159/000363137
  • Effect of buttermilk consumption on blood pressure in moderately hypercholesterolemic men and women, Conway, V., Couture, P., Gauthier, S., Pouliot, Y., Lamarche, B., Nutrition, 2014, 10.1016/j.nut.2013.07.021
  • Effect of mediterranean diet with and without weight loss on apolipoprotein b100 metabolism in men with metabolic syndrome, Richard, C., Couture, P., Ooi, E.M.M., Tremblay, A.J., Desroches, S., Charest, A., Lichtenstein, A.H., Lamarche, B., Arteriosclerosis, Thrombosis, and Vascular Biology, 2014, 10.1161/ATVBAHA.113.302185
  • Effect of sitagliptin therapy on triglyceride-rich lipoprotein kinetics in patients with type 2 diabetes, Tremblay, A.J., Lamarche, B., Kelly, I., Charest, A., Lépine, M.-C., Droit, A., Couture, P., Diabetes, Obesity and Metabolism, 2014, 10.1111/dom.12359
  • Effects of FADS and ELOVL polymorphisms on indexes of desaturase and elongase activities: Results from a pre-post fish oil supplementation, Cormier, H., Rudkowska, I., Lemieux, S., Couture, P., Julien, P., Vohl, M.-C., Genes and Nutrition, 2014, 10.1007/s12263-014-0437-z
  • Effects of sitagliptin therapy on markers of low-grade inflammation and cell adhesion molecules in patients with type 2 diabetes, Tremblay, A.J., Lamarche, B., Deacon, C.F., Weisnagel, S.J., Couture, P., Metabolism: Clinical and Experimental, 2014, 10.1016/j.metabol.2014.06.004
  • Gene-diet interactions with polymorphisms of the MGLL gene on plasma low-density lipoprotein cholesterol and size following an omega-3 polyunsaturated fatty acid supplementation: A clinical trial, Ouellette, C., Rudkowska, I., Lemieux, S., Lamarche, B., Couture, P., Vohl, M.-C., Lipids in Health and Disease, 2014, 10.1186/1476-511X-13-86
  • Genome-wide association study of the plasma triglyceride response to an n-3 polyunsaturated fatty acid supplementation, Rudkowska, I., Guénard, F., Julien, P., Couture, P., Lemieux, S., Barbier, O., Calder, P.C., Minihane, A.M., Vohl, M.-C., Journal of Lipid Research, 2014, 10.1194/jlr.M045898
  • Impact of dairy consumption on essential hypertension: A clinical study, Drouin-Chartier, J.-P., Gigleux, I., Tremblay, A.J., Poirier, L., Lamarche, B., Couture, P., Nutrition Journal, 2014, 10.1186/1475-2891-13-83
  • Impact of the Mediterranean Diet on Features of Metabolic Syndrome: Is Weight Loss Required?, Richard, C., Couture, P., Lamarche, B., The Mediterranean Diet: An Evidence-Based Approach, 2014, 10.1016/B978-0-12-407849-9.00030-0
  • It is time to revisit current dietary recommendations for saturated fat, Lamarche, B., Couture, P., Applied Physiology, Nutrition and Metabolism, 2014, 10.1139/apnm-2014-0141
  • Key intestinal genes involved in lipoprotein metabolism are downregulated in dyslipidemic men with insulin resistance, Couture, P., Tremblay, A.J., Kelly, I., Lemelin, V., Droit, A., Lamarche, B., Journal of Lipid Research, 2014, 10.1194/jlr.M040071
  • Polymorphisms in genes involved in fatty acid β-oxidation interact with dietary fat intakes to modulate the plasma TG response to a fish oil supplementation, Bouchard-Mercier, A., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C., Nutrients, 2014, 10.3390/nu6031145
  • Proceedings from the 2013 Canadian Nutrition Society Conference on Advances in Dietary Fats and Nutrition, Holub, B., Mutch, D.M., Pierce, G.N., Rodriguez-Leyva, D., Aliani, M., Innis, S., Yan, W., Lamarche, B., Couture, P., Ma, D.W.L., Applied Physiology, Nutrition and Metabolism, 2014, 10.1139/apnm-2013-0418
  • Relations of change in plasma levels of LDL-C, non-HDL-C and apoB with risk reduction from statin therapy: a meta-analysis of randomized trials., Thanassoulis, G., Williams, K., Ye, K., Brook, R., Couture, P., Lawler, P.R., de Graaf, J., Furberg, C.D., Sniderman, A., Journal of the American Heart Association, 2014, 10.1161/JAHA.113.000759
  • SREBF1 gene variations modulate insulin sensitivity in response to a fish oil supplementation, Bouchard-Mercier, A., Rudkowska, I., Lemieux, S., Couture, P., Pérusse, L., Vohl, M.-C., Lipids in Health and Disease, 2014, 10.1186/1476-511X-13-152
  • Traditional dietary pattern is associated with elevated cholesterol among the Inuit of Nunavik, Labonté, M.-T., Dewailly, E., Lucas, M., Chateau-Degat, M.-L., Couture, P., Lamarche, B., Journal of the Academy of Nutrition and Dietetics, 2014, 10.1016/j.jand.2013.12.017
  • 2012 Update of the Canadian Cardiovascular Society Guidelines for the Diagnosis and Treatment of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult, Anderson, T.J., Grégoire, J., Hegele, R.A., Couture, P., Mancini, G.B.J., McPherson, R., Francis, G.A., Poirier, P., Lau, D.C., Grover, S., Genest, J., Carpentier, A.C., Dufour, R., Gupta, M., Ward, R., Leiter, L.A., Lonn, E., Ng, D.S., Pearson, G.J., Yates, G.M., Stone, J.A., Ur, E., Canadian Journal of Cardiology, 2013, 10.1016/j.cjca.2012.11.032
  • Abdominal obesity, insulin resistance, metabolic syndrome and cholesterol homeostasis, Taverne, F., Richard, C., Couture, P., Lamarche, B., PharmaNutrition, 2013, 10.1016/j.phanu.2013.07.003
  • Adding MUFA to a dietary portfolio of cholesterol-lowering foods reduces apoAI fractional catabolic rate in subjects with dyslipidaemia, Labonté, M.-E., Jenkins, D.J.A., Lewis, G.F., Chiavaroli, L., Wong, J.M.W., Kendall, C.W.C., Hogue, J.-C., Couture, P., Lamarche, B., British Journal of Nutrition, 2013, 10.1017/S000711451200534X
  • Associations between dietary patterns and gene expression profiles of healthy men and women: A cross-sectional study, Bouchard-Mercier, A., Paradis, A.-M., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C., Nutrition Journal, 2013, 10.1186/1475-2891-12-24
  • Correlates of reactive hyperemic index in men and postmenopausal women, Carnovale, V., Paradis, M.-E., Gigleux, I., Ramprasath, V.R., Couture, P., Jones, P.J., Lamarche, B., Couillard, C., Vascular Medicine (United Kingdom), 2013, 10.1177/1358863X13507975
  • Counterpoint: Statins do reduce fatal events, Sniderman, A.D., Thanassoulis, G., Couture, P., Williams, K., Alam, A., Furberg, C.D., Journal of Clinical Lipidology, 2013, 10.1016/j.jacl.2012.12.004
  • Differences in metabolomic and transcriptomic profiles between responders and non-responders to an n-3 polyunsaturated fatty acids (PUFAs) supplementation, Rudkowska, I., Paradis, A.-M., Thifault, E., Julien, P., Barbier, O., Couture, P., Lemieux, S., Vohl, M.-C., Genes and Nutrition, 2013, 10.1007/s12263-012-0328-0
  • Effect of an isoenergetic traditional Mediterranean diet on apolipoprotein A-I kinetic in men with metabolic syndrome, Richard, C., Couture, P., Desroches, S., Lichtenstein, A.H., Lamarche, B., Nutrition Journal, 2013, 10.1186/1475-2891-12-76
  • Effect of the Mediterranean diet on plasma adipokine concentrations in men with metabolic syndrome, Richard, C., Royer, M.-M., Couture, P., Cianflone, K., Rezvani, R., Desroches, S., Lamarche, B., Metabolism: Clinical and Experimental, 2013, 10.1016/j.metabol.2013.07.012
  • Effect of the mediterranean diet with and without weight loss on markers of inflammation in men with metabolic syndrome, Lamarche, B., Richard, C., Couture, P., Desroches, S., Obesity, 2013, 10.1038/oby.2012.148
  • Effect of weight loss, independent of change in diet composition, on apolipoprotein AI kinetic in men with metabolic syndrome, Richard, C., Couture, P., Desroches, S., Lichtenstein, A.H., Lamarche, B., Journal of Lipid Research, 2013, 10.1194/jlr.M029934
  • Effects of age, sex, body mass index and APOE genotype on cardiovascular biomarker response to an n-3 polyunsaturated fatty acid supplementation, Thifault, E., Cormier, H., Bouchard-Mercier, A., Rudkowska, I., Paradis, A.-M., Garneau, V., Ouellette, C., Lemieux, S., Couture, P., Vohl, M.-C., Journal of Nutrigenetics and Nutrigenomics, 2013, 10.1159/000350744
  • Eicosapentaenoic and docosahexaenoic acid supplementation and inflammatory gene expression in the duodenum of obese patients with type 2 diabetes, Labonté, M.-E., Couture, P., Tremblay, A.J., Hogue, J.-C., Lemelin, V., Lamarche, B., Nutrition Journal, 2013, 10.1186/1475-2891-12-98
  • Evidence that cranberry juice may improve augmentation index in overweight men, Ruel, G., Lapointe, A., Pomerleau, S., Couture, P., Lemieux, S., Lamarche, B., Couillard, C., Nutrition Research, 2013, 10.1016/j.nutres.2012.11.002
  • Ezetimibe and bile acid sequestrants: Impact on lipoprotein metabolism and beyond, Couture, P., Lamarche, B., Current Opinion in Lipidology, 2013, 10.1097/MOL.0b013e3283613a55
  • Impact of buttermilk consumption on plasma lipids and surrogate markers of cholesterol homeostasis in men and women, Conway, V., Couture, P., Richard, C., Gauthier, S.F., Pouliot, Y., Lamarche, B., Nutrition, Metabolism and Cardiovascular Diseases, 2013, 10.1016/j.numecd.2013.03.003
  • Impact of dairy products on biomarkers of inflammation: A systematic review of randomized controlled nutritional intervention studies in overweight and obese adults, Labonté, M.-E., Couture, P., Richard, C., Desroches, S., Lamarche, B., American Journal of Clinical Nutrition, 2013, 10.3945/ajcn.112.052217
  • PCSK9 plays a significant role in cholesterol homeostasis and lipid transport in intestinal epithelial cells, Levy, E., Ouadda, A.B.D., Spahis, S., Sane, A.T., Garofalo, C., Grenier, T., Emonnot, L., Yara, S., Couture, P., Beaulieu, J.-F., Ménard, D., Seidah, N.G., Elchebly, M., Atherosclerosis, 2013, 10.1016/j.atherosclerosis.2013.01.023
  • Polymorphisms in Fatty Acid Desaturase (FADS) gene cluster: Effects on glycemic controls following an omega-3 Polyunsaturated Fatty Acids (PUFA) supplementation, Cormier, H., Rudkowska, I., Thifault, E., Lemieux, S., Couture, P., Vohl, M.-C., Genes, 2013, 10.3390/genes4030485
  • Polymorphisms in genes involved in the triglyceride synthesis pathway and marine omega-3 polyunsaturated fatty acid supplementation modulate plasma triglyceride levels, Ouellette, C., Cormier, H., Rudkowska, I., Guénard, F., Lemieux, S., Couture, P., Vohl, M.-C., Journal of Nutrigenetics and Nutrigenomics, 2013, 10.1159/000357432
  • Polymorphisms, de novo lipogenesis, and plasma triglyceride response following fish oil supplementation, Bouchard-Mercier, A., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C., Journal of Lipid Research, 2013, 10.1194/jlr.M041590
  • Short-term, high-fat diet increases the expression of key intestinal genes involved in lipoprotein metabolism in healthy men, Tremblay, A.J., Lamarche, B., Guay, V., Charest, A., Lemelin, V., Couture, P., American Journal of Clinical Nutrition, 2013, 10.3945/ajcn.113.060251
  • The metabolic signature associated with the Western dietary pattern: A cross-sectional study, Bouchard-Mercier, A., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C., Nutrition Journal, 2013, 10.1186/1475-2891-12-158
  • Transcriptomic and metabolomic signatures of an n-3 polyunsaturated fatty acids supplementation in a normolipidemic/normocholesterolemic Caucasian population, Rudkowska, I., Paradis, A.-M., Thifault, E., Julien, P., Tchernof, A., Couture, P., Lemieux, S., Barbier, O., Vohl, M.-C., Journal of Nutritional Biochemistry, 2013, 10.1016/j.jnutbio.2012.01.016
  • Association between polymorphisms in the fatty acid desaturase gene cluster and the plasma triacylglycerol response to an n-3 PUFA supplementation, Cormier, H., Rudkowska, I., Paradis, A.-M., Thifault, E., Garneau, V., Lemieux, S., Couture, P., Vohl, M.-C., Nutrients, 2012, 10.3390/nu4081026
  • Clinical and molecular characterization of a severe form of partial lipodystrophy expanding the phenotype of PPARγ deficiency, Campeau, P.M., Astapova, O., Martins, R., Bergeron, J., Couture, P., Hegele, R.A., Leff, T., Gagné, C., Journal of Lipid Research, 2012, 10.1194/jlr.P025437
  • Effect of short-term low- and high-fat diets on low-density lipoprotein particle size in normolipidemic subjects, Guay, V., Lamarche, B., Charest, A., Tremblay, A.J., Couture, P., Metabolism: Clinical and Experimental, 2012, 10.1016/j.metabol.2011.06.002
  • Effect of the Mediterranean diet with and without weight loss on surrogate markers of cholesterol homeostasis in men with the metabolic syndrome, Richard, C., Couture, P., Desroches, S., Benjannet, S., Seidah, N.G., Lichtenstein, A.H., Lamarche, B., British Journal of Nutrition, 2012, 10.1017/S0007114511003436
  • Is lower and lower better and better? A re-evaluation of the evidence from the Cholesterol Treatment Trialists' Collaboration meta-analysis for low-density lipoprotein lowering, Sniderman, A., Thanassoulis, G., Couture, P., Williams, K., Alam, A., Furberg, C.D., Journal of Clinical Lipidology, 2012, 10.1016/j.jacl.2012.05.004
  • Low-density lipoprotein-lowering strategies: Target versus maximalist versus population percentile, Sniderman, A.D., De Graaf, J., Couture, P., Current Opinion in Cardiology, 2012, 10.1097/HCO.0b013e328353fed5
  • Phenotypes of hypertriglyceridemia caused by excess very-low-density lipoprotein, Sniderman, A.D., Tremblay, A., De Graaf, J., Couture, P., Journal of Clinical Lipidology, 2012, 10.1016/j.jacl.2012.04.081
  • Population-based study of high plasma C-reactive protein concentrations among the Inuit of Nunavik, Labonté, M.-E., Dewailly, E., Chateau-Degat, M.-L., Couture, P., Lamarche, B., International Journal of Circumpolar Health, 2012, 10.3402/ijch.v71i0.19066
  • Randomized controlled study of the effect of a butter naturally enriched in trans fatty acids on blood lipids in healthy women, Lacroix, É., Charest, A., Cyr, A., Baril-Gravel, L., Lebeuf, Y., Paquin, P., Chouinard, P.Y., Couture, P., Lamarche, B., American Journal of Clinical Nutrition, 2012, 10.3945/ajcn.111.023408
  • A novel mutation of apolipoprotein B in a French Canadian family with homozygous hypobetalipoproteinemia, Gangloff, A., Bergeron, J., Couture, P., Martins, R., Hegele, R.A., Gagné, C., Journal of Clinical Lipidology, 2011, 10.1016/j.jacl.2011.06.014
  • A randomised crossover placebo-controlled trial investigating the effect of brown seaweed (Ascophyllum nodosum and fucus vesiculosus) on postchallenge plasma glucose and insulin levels in men and women, Paradis, M.-E., Couture, P., Lamarche, B., Applied Physiology, Nutrition and Metabolism, 2011, 10.1139/H11-115
  • Atorvastatin increases intestinal expression of NPC1L1 in hyperlipidemic men, Tremblay, A.J., Lamarche, B., Lemelin, V., Hoos, L., Benjannet, S., Seidah, N.G., Davis Jr., H.R., Couture, P., Journal of Lipid Research, 2011, 10.1194/jlr.M011080
  • Comparison of the impact of trans fatty acids from ruminant and industrial sources on surrogate markers of cholesterol homeostasis in healthy men, Labonté, M.-E., Couture, P., Paquin, P., Chouinard, Y., Lemieux, S., Lamarche, B., Molecular Nutrition and Food Research, 2011, 10.1002/mnfr.201000492
  • Effect of sitagliptin therapy on postprandial lipoprotein levels in patients with type 2 diabetes, Tremblay, A.J., Lamarche, B., Deacon, C.F., Weisnagel, S.J., Couture, P., Diabetes, Obesity and Metabolism, 2011, 10.1111/j.1463-1326.2011.01362.x
  • Effect of the Mediterranean diet with and without weight loss on cardiovascular risk factors in men with the metabolic syndrome, Richard, C., Couture, P., Desroches, S., Charest, A., Lamarche, B., Nutrition, Metabolism and Cardiovascular Diseases, 2011, 10.1016/j.numecd.2010.01.012
  • Effects of neuromedin-β on caloric compensation, eating behaviours and habitual food intake, Blanchet, R., Lemieux, S., Couture, P., Bouchard, L., Vohl, M.-C., Pérusse, L., Appetite, 2011, 10.1016/j.appet.2011.04.003
  • Expression of sar1b enhances chylomicron assembly and key components of the coat protein complex II system driving vesicle budding, Levy, E., Harmel, E., Laville, M., Sanchez, R., Emonnot, L., Sinnett, D., Ziv, E., Delvin, E., Couture, P., Marcil, V., Sane, A.T., Arteriosclerosis, Thrombosis, and Vascular Biology, 2011, 10.1161/ATVBAHA.111.233908
  • Impact of the Mediterranean diet with and without weight loss on plasma cell adhesion molecule concentrations in men with the metabolic syndrome, Richard, C., Couillard, C., Royer, M.-M., Desroches, S., Couture, P., Lamarche, B., Mediterranean Journal of Nutrition and Metabolism, 2011, 10.1007/s12349-010-0029-4
  • Assessment of the validity of the frequently used lipid indices for predicting LDL peak particle diameter in a large cohort of 1955 normal and dyslipidemic subjects, Décary, S., Dumont, G., Lamarche, B., Hogue, J.-C., Tremblay, A.J., Bergeron, J., Couture, P., Clinical Biochemistry, 2010, 10.1016/j.clinbiochem.2009.11.010
  • Diagnosis and treatment of apolipoprotein B dyslipoproteinemias, Sniderman, A., Couture, P., De Graaf, J., Nature Reviews Endocrinology, 2010, 10.1038/nrendo.2010.50
  • PPARα L162V polymorphism alters the potential of n-3 fatty acids to increase lipoprotein lipase activity, Rudkowska, I., Caron-Dorval, D., Verreault, M., Couture, P., Deshaies, Y., Barbier, O., Vohl, M.-C., Molecular Nutrition and Food Research, 2010, 10.1002/mnfr.200900085
  • Regulation of plasma LDL: The apoB paradigm, Sniderman, A.D., De Graaf, J., Couture, P., Williams, K., Kiss, R.S., Watts, G.F., Clinical Science, 2010, 10.1042/CS20090402
  • 2009 Canadian Cardiovascular Society/Canadian guidelines for the diagnosis and treatment of dyslipidemia and prevention of cardiovascular disease in the adult - 2009 recommendations, Genest, J., McPherson, R., Frohlich, J., Anderson, T., Campbell, N., Carpentier, A., Couture, P., Dufour, R., Fodor, G., Francis, G.A., Grover, S., Gupta, M., Hegele, R.A., Lau, D.C., Leiter, L., Lewis, G.F., Lonn, E., Mancini, G.B.J., Ng, D., Pearson, G.J., Sniderman, A., Stone, J.A., Ur, E., Canadian Journal of Cardiology, 2009, 10.1016/S0828-282X(09)70715-9
  • Aortic calcifications in familial hypercholesterolemia: Potential role of the low-density lipoprotein receptor gene, Alrasadi, K., Alwaili, K., Awan, Z., Valenti, D., Couture, P., Genest, J., American Heart Journal, 2009, 10.1016/j.ahj.2008.08.021
  • Effects of ezetimibe and simvastatin on apolipoprotein B metabolism in males with mixed hyperlipidemia, Tremblay, A.J., Lamarche, B., Hogue, J.-C., Couture, P., Journal of Lipid Research, 2009, 10.1194/jlr.P800061-JLR200
  • Omega-3 fatty acids regulate gene expression levels differently in subjects carrying the PPARα L162V polymorphism, Rudkowska, I., Garenc, C., Couture, P., Vohl, M.-C., Genes and Nutrition, 2009, 10.1007/s12263-009-0129-2
  • Plasma matrix metalloproteinase (mmp)-9 levels are reduced following low-calorie cranberry juice supplementation in men, Ruel, G., Pomerleau, S., Couture, P., Lemieux, S., Couillard, C., Couillard, C., Journal of the American College of Nutrition, 2009, 10.1080/07315724.2009.10719803
  • Plasma n-3 fatty acid response to an n-3 fatty acid supplement is modulated by apoE 4 but not by the common PPAR- L162V polymorphism in men, Plourde, M., Vohl, M.-C., Vandal, M., Couture, P., Lemieux, S., Cunnane, S.C., British Journal of Nutrition, 2009, 10.1017/S000711450938215X
  • A diagnostic algorithm for the atherogenic apolipoprotein B dyslipoproteinemias, De Graaf, J., Couture, P., Sniderman, A., Nature Clinical Practice Endocrinology and Metabolism, 2008, 10.1038/ncpendmet0982
  • Differential effect of atorvastatin and fenofibrate on plasma oxidized low-density lipoprotein, inflammation markers, and cell adhesion molecules in patients with type 2 diabetes mellitus, Hogue, J.-C., Lamarche, B., Tremblay, A.J., Bergeron, J., Gagné, C., Couture, P., Metabolism: Clinical and Experimental, 2008, 10.1016/j.metabol.2007.10.014
  • Differential effect of fenofibrate and atorvastatin on in vivo kinetics of apolipoproteins B-100 and B-48 in subjects with type 2 diabetes mellitus with marked hypertriglyceridemia, Hogue, J.-C., Lamarche, B., Deshaies, Y., Tremblay, A.J., Bergeron, J., Gagné, C., Couture, P., Metabolism: Clinical and Experimental, 2008, 10.1016/j.metabol.2007.09.008
  • Effect of the PPAR-alpha L162V polymorphism on the cardiovascular disease risk factor in response to n-3 polyunsaturated fatty acids, Caron-Dorval, D., Paquet, P., Paradis, A.-M., Rudkowska, I., Lemieux, S., Couture, P., Vohl, M.-C., Journal of Nutrigenetics and Nutrigenomics, 2008, 10.1159/000137555
  • Intravascular kinetics of C-reactive protein and their relationships with features of the metabolic syndrome, Mauger, J.-F., Lévesque, J., Paradis, M.-E., Bergeron, N., Tchernof, A., Couture, P., Lamarche, B., Journal of Clinical Endocrinology and Metabolism, 2008, 10.1210/jc.2007-2585
  • Kinetics of plasma apolipoprotein C-III as a determinant of diet-induced changes in plasma triglyceride levels, Desroches, S., Ruel, I.L., Deshaies, Y., Paradis, M.-E., Archer, W.R., Couture, P., Bergeron, N., Lamarche, B., European Journal of Clinical Nutrition, 2008, 10.1038/sj.ejcn.1602673
  • Low-calorie cranberry juice supplementation reduces plasma oxidized LDL and cell adhesion molecule concentrations in men, Ruel, G., Pomerleau, S., Couture, P., Lemieux, S., Lamarche, B., Couillard, C., British Journal of Nutrition, 2008, 10.1017/S0007114507811986
  • Non-HDL cholesterol and apoB in dyslipidaemia, Sniderman, A.D., Hogue, J.-C., Bergeron, J., Gagné, C., Couture, P., Clinical Science, 2008, 10.1042/CS20070265
  • Study of the effect of trans fatty acids from ruminants on blood lipids and other risk factors for cardiovascular disease, Motard-Bélanger, A., Charest, A., Grenier, G., Paquin, P., Chouinard, Y., Lemieux, S., Couture, P., Lamarche, B., American Journal of Clinical Nutrition, 2008
  • Vascular calcifications in homozygote familial hypercholesterolemia, Awan, Z., Alrasadi, K., Francis, G.A., Hegele, R.A., McPherson, R., Frohlich, J., Valenti, D., De Varennes, B., Marcil, M., Gagne, C., Genest, J., Couture, P., Arteriosclerosis, Thrombosis, and Vascular Biology, 2008, 10.1161/ATVBAHA.107.160408
  • Association of heterozygous familial hypercholesterolemia with smaller HDL particle size, Hogue, J.-C., Lamarche, B., Gaudet, D., Tremblay, A.J., Després, J.-P., Bergeron, J., Gagné, C., Couture, P., Atherosclerosis, 2007, 10.1016/j.atherosclerosis.2006.02.023
  • Diagnosis of type III hyperlipoproteinemia from plasma total cholesterol, triglyceride, and apolipoprotein B, Sniderman, A., Tremblay, A., Bergeron, J., Gagné, C., Couture, P., Journal of Clinical Lipidology, 2007, 10.1016/j.jacl.2007.07.006
  • Differential impact of plasma triglycerides on HDL-cholesterol and HDL-apo A-I in a large cohort, Tremblay, A.J., Sniderman, A.D., Gagné, C., Bergeron, J., Couture, P., Clinical Biochemistry, 2007, 10.1016/j.clinbiochem.2006.06.014
  • Effect of a six-week National Cholesterol Education Program step 1 diet on plasma sex hormone-binding globulin levels in overweight premenopausal women, Blouin, K., Robitaille, J., Bélanger, C., Fontaine-Bisson, B., Couture, P., Vohl, M.-C., Tchernof, A., Metabolic Syndrome and Related Disorders, 2007, 10.1089/met.2006.0005
  • Evidence of increased secretion of apolipoprotein B-48-containing lipoproteins in subjects with type 2 diabetes, Hogue, J.-C., Lamarche, B., Tremblay, A.J., Bergeron, J., Gagné, C., Couture, P., Journal of Lipid Research, 2007, 10.1194/jlr.M600548-JLR200
  • Apo B versus cholesterol in estimating cardiovascular risk and in guiding therapy: Report of the thirty-person/ten-country panel, Barter, P.J., Ballantyne, C.M., Carmena, R., Cabezas, M.C., Chapman, M.J., Couture, P., De Graaf, J., Durrington, P.N., Faergeman, O., Frohlich, J., Furberg, C.D., Gagne, C., Haffner, S.M., Humphries, S.E., Jungner, I., Krauss, R.M., Kwiterovich, P., Marcovina, S., Packard, C.J., Pearson, T.A., Reddy, K.S., Rosenson, R., Sarrafzadegan, N., Sniderman, A.D., Stalenhoef, A.F., Stein, E., Talmud, P.J., Tonkin, A.M., Walldius, G., Williams, K.M.S., Journal of Internal Medicine, 2006, 10.1111/j.1365-2796.2006.01616.x
  • Apolipoprotein C-III isoforms: Kinetics and relative implication in lipid metabolism, Mauger, J.-F., Couture, P., Bergeron, N., Lamarche, B., Journal of Lipid Research, 2006, 10.1194/jlr.M500455-JLR200
  • Associations between hypertriglyceridemia, dietary fat intake, oxidative stress, and endothelial activation in men, Couillard, C., Pomerleau, S., Ruel, G., Archer, W.R., Bergeron, J., Couture, P., Lamarche, B., Bergeron, N., Nutrition, 2006, 10.1016/j.nut.2006.03.007
  • Baseline plasma C-reactive protein concentrations influence lipid and lipoprotein responses to low-fat and high monounsaturated fatty acid diets in healthy men, Desroches, S., Archer, W.R., Paradis, M.-E., Dériaz, O., Couture, P., Bergeron, J., Bergeron, N., Lamarche, B., Journal of Nutrition, 2006
  • Clinical significance and treatment of hypertriglyceridemia, Couture, P., Gilbert, N., Geriatrics and Aging, 2006
  • Effect of ezetimibe on the in vivo kinetics of apoB-48 and apoB-100 in men with primary hypercholesterolemia, Tremblay, A.J., Lamarche, B., Cohn, J.S., Hogue, J.-C., Couture, P., Arteriosclerosis, Thrombosis, and Vascular Biology, 2006, 10.1161/01.ATV.0000216750.09611.ec
  • Effects of fenofibrate on apolipoprotein kinetics in patients with coexisting dysbetalipoproteinemia and heterozygous familial hypercholesterolemia, Tremblay, A.J., Lamarche, B., Ruel, I.L., Hogue, J.-C., Deshaies, Y., Gagné, C., Couture, P., Atherosclerosis, 2006, 10.1016/j.atherosclerosis.2005.10.037
  • Endothelial lipase is associated with inflammation in humans, Paradis, M.-E., Badellino, K.O., Rader, D.J., Deshaies, Y., Couture, P., Archer, W.R., Bergeron, N., Lamarche, B., Journal of Lipid Research, 2006, 10.1194/jlr.P600002-JLR200
  • Favourable impact of low-calorie cranberry juice consumption on plasma HDL-cholesterol concentrations in men, Ruel, G., Pomerleau, S., Couture, P., Lemieux, S., Lamarche, B., Couillard, C., British Journal of Nutrition, 2006, 10.1079/BJN20061814
  • Genotype of the mutant LDL receptor allele is associated with LDL particle size heterogeneity in familial hypercholesterolemia, Hogue, J.-C., Lamarche, B., Gaudet, D., Tremblay, A.J., Després, J.-P., Gagné, C., Couture, P., Atherosclerosis, 2006, 10.1016/j.atherosclerosis.2005.03.027
  • Visceral adipose tissue accumulation, secretory phospholipase A 2-IIA and atherogenecity of LDL, Paradis, M.-E., Hogue, M.-O., Mauger, J.-F., Couillard, C., Couture, P., Bergeron, N., Lamarche, B., International Journal of Obesity, 2006, 10.1038/sj.ijo.0803315
  • Visceral adiposity and endothelial lipase, Paradis, M.-E., Badellino, K.O., Rader, D.J., Tchernof, A., Richard, C., Luu-The, V., Deshaies, Y., Bergeron, J., Archer, W.R., Couture, P., Bergeron, N., Lamarche, B., Journal of Clinical Endocrinology and Metabolism, 2006, 10.1210/jc.2006-0766
  • Changes in plasma antioxidant capacity and oxidized low-density lipoprotein levels in men after short-term cranberry juice consumption, Ruel, G., Pomerleau, S., Couture, P., Lamarche, B., Couillard, C., Metabolism: Clinical and Experimental, 2005, 10.1016/j.metabol.2005.01.031
  • Chronic venous abnormalities in symptomatic and asymptomatic protein C deficiency, Emmerich, J., Vossen, C.Y., Callas, P.W., Demers, C., Naud, S., Long, G.L., Couture, P., Rosendaal, F.R., Bovill, E.G., Journal of Thrombosis and Haemostasis, 2005, 10.1111/j.1538-7836.2005.01452.x
  • Circulating levels of oxidative stress markers and endothelial adhesion molecules in men with abdominal obesity, Couillard, C., Ruel, G., Archer, W.R., Pomerleau, S., Bergeron, J., Couture, P., Lamarche, B., Bergeron, N., Journal of Clinical Endocrinology and Metabolism, 2005, 10.1210/jc.2004-2438
  • Comparison of the impact of atorvastatin and simvastatin on apoA-I kinetics in men, Mauger, J.-F., Couture, P., Paradis, M.-E., Lamarche, B., Atherosclerosis, 2005, 10.1016/j.atherosclerosis.2004.06.022
  • Effect of an oat bran-rich supplement on the metabolic profile of overweight premenopausal women, Robitaille, J., Fontaine-Bisson, B., Couture, P., Tchernof, A., Vohl, M.-C., Annals of Nutrition and Metabolism, 2005, 10.1159/000086149
  • Effect of fenofibrate on plasma lipoprotein composition and kinetics in patients with complete hepatic lipase deficiency, Ruel, I.L., Lamarche, B., Mauger, J.-F., Badellino, K.O., Cohn, J.S., Marcil, M., Couture, P., Arteriosclerosis, Thrombosis, and Vascular Biology, 2005, 10.1161/01.ATV.0000190700.76493.bb
  • Effect of the APOC3 Sst I SNP on fasting triglyceride levels in men heterozygous for the LPL P207L deficiency, Garenc, C., Couillard, C., Laflamme, N., Cadelis, F., Gagné, C., Couture, P., Julien, P., Bergeron, J., European Journal of Human Genetics, 2005, 10.1038/sj.ejhg.5201469
  • Influence of apolipoprotein E genotype on the reliability of the Friedewald formula in the estimation of low-density lipoprotein cholesterol concentrations, Tremblay, A.J., Bergeron, J., Gagné, J.-M., Gagné, C., Couture, P., Metabolism: Clinical and Experimental, 2005, 10.1016/j.metabol.2005.03.003
  • Lack of effect of dietary conjugated linoleic acids naturally incorporated into butter on the lipid profile and body composition of overweight and obese men, Desroches, S., Chouinard, P.Y., Galibois, I., Corneau, L., Delisle, J., Lamarche, B., Couture, P., Bergeron, N., American Journal of Clinical Nutrition, 2005
  • Plasma metabolism of apoB-containing lipoproteins in patients with hepatic lipase deficiency, Ruel, I.L., Couture, P., Cohn, J.S., Lamarche, B., Atherosclerosis, 2005, 10.1016/j.atherosclerosis.2004.12.014
  • The peroxisome proliferator-activated receptor α Leu162Val polymorphism influences the metabolic response to a dietary intervention altering fatty acid proportions in healthy men, Paradis, A.-M., Fontaine-Bisson, B., Bossé, Y., Robitaille, J., Lemieux, S., Jacques, H., Lamarche, B., Tchernof, A., Couture, P., Vohl, M.-C., American Journal of Clinical Nutrition, 2005
  • Variations in plasma apolipoprotein C-III levels are strong correlates of the triglyceride response to a high-monounsaturated fatty acid diet and a high-carbohydrate diet, Archer, W.R., Desroches, S., Lamarche, B., Dériaz, O., Landry, N., Fontaine-Bisson, B., Bergeron, J., Couture, P., Bergeron, N., Metabolism: Clinical and Experimental, 2005, 10.1016/j.metabol.2005.05.004
  • Apolipoprotein A-I, A-II, and VLDL-B-100 metabolism in men: Comparison of a low-fat diet and a high-monounsaturated fatty acid diet, Desroches, S., Paradis, M.-E., Pérusse, M., Archer, W.R., Bergeron, J., Couture, P., Bergeron, N., Lamarche, B., Journal of Lipid Research, 2004, 10.1194/jlr.M400287-JLR200
  • Evidence that hepatic lipase deficiency in humans is not associated with proatherogenic changes in HDL composition and metabolism, Ruel, I.L., Couture, P., Cohn, J.S., Bensadoun, A., Marcil, M., Lamarche, B., Journal of Lipid Research, 2004, 10.1194/jlr.M400090-JLR200
  • Increased production of VLDL apoB-100 in subjects with familial hypercholesterolemia carrying the same null LDL receptor gene mutation, Tremblay, A.J., Lamarche, B., Ruel, I.L., Hogue, J.-C., Bergeron, J., Gagné, C., Couture, P., Journal of Lipid Research, 2004, 10.1194/jlr.M300448-JLR200
  • Lack of evidence for reduced plasma apo B48 catabolism in patients with heterozygous familial hypercholesterolemia carrying the same null LDL receptor gene mutation, Tremblay, A.J., Lamarche, B., Ruel, I., Hogue, J.-C., Bergeron, J., Gagné, C., Couture, P., Atherosclerosis, 2004, 10.1016/j.atherosclerosis.2003.11.011
  • Molecular screening of the microsomal triglyceride transfer protein: Association between polymorphisms and both abdominal obesity and plasma apolipoprotein B concentration, Berthier, M.-T., Houde, A., Paradis, A.-M., Couture, P., Gaudet, D., Després, J.-P., Vohl, M.-C., Journal of Human Genetics, 2004, 10.1007/s10038-004-0207-7
  • Relationship between cholesteryl ester transfer protein and LDL heterogeneity in familial hypercholesterolemia, Hogue, J.-C., Lamarche, B., Gaudet, D., Larivière, M., Tremblay, A.J., Bergeron, J., Lemieux, I., Després, J.-P., Gagné, C., Couture, P., Journal of Lipid Research, 2004, 10.1194/jlr.M300420-JLR200
  • The c.419-420insA in the MTP gene is associated with abetalipoproteinemia among French-Canadians, Berthier, M.-T., Couture, P., Houde, A., Paradis, A.-M., Sammak, A., Verner, A., Deprés, J.-P., Gagné, C., Gaudet, D., Vohl, M.-C., Molecular Genetics and Metabolism, 2004, 10.1016/j.ymgme.2003.11.001
  • Validation of the Friedewald formula for the determination of low-density lipoprotein cholesterol compared with β-quantification in a large population, Tremblay, A.J., Morrissette, H., Gagné, J.-M., Bergeron, J., Gagné, C., Couture, P., Clinical Biochemistry, 2004, 10.1016/j.clinbiochem.2004.03.008
  • Characterization of a novel mutation causing hepatic lipase deficiency among French Canadians, Ruel, I.L., Couture, P., Gagné, C., Deshaies, Y., Simard, J., Hegele, R.A., Lamarche, B., Journal of Lipid Research, 2003, 10.1194/jlr.M200479-JLR200
  • Effects of atorvastatin on electrophoretic characteristics of LDL particles among subjects with heterozygous familial hypercholesterolemia, Larivière, M., Lamarche, B., Pirro, M., Hogue, J.-C., Bergeron, J., Gagné, C., Couture, P., Atherosclerosis, 2003, 10.1016/S0021-9150(02)00385-4
  • High carbohydrate and high monounsaturated fatty acid diets similarly affect LDL electrophoretic characteristics in men who are losing weight, Archer, W.R., Lamarche, B., St-Pierre, A.C., Mauger, J.-F., Dériaz, O., Landry, N., Corneau, L., Després, J.-P., Bergeron, J., Couture, P., Bergeron, N., Journal of Nutrition, 2003
  • Influences of apolipoprotein E polymorphism on the response of plasma lipids to the ad libitum consumption of a high-carbohydrate diet compared with a high-monounsaturated fatty acid diet, Couture, P., Archer, W.R., Lamarche, B., Landry, N., Dériaz, O., Corneau, L., Bergeron, J., Bergeron, N., Metabolism: Clinical and Experimental, 2003, 10.1016/S0026-0495(03)00275-0
  • Subdivision of the subcutaneous adipose tissue compartment and lipid-lipoprotein levels in women, Deschênes, D., Couture, P., Dupont, P., Tchernof, A., Obesity Research, 2003, 10.1038/oby.2003.64
  • The T111I mutation in the EL gene modulates the impact of dietary fat on the HDL profile in women, Paradis, M.-E., Couture, P., Bossé, Y., Després, J.-P., Pérusse, L., Bouchard, C., Vohl, M.-C., Lamarche, B., Journal of Lipid Research, 2003, 10.1194/jlr.M300118-JLR200
  • Variations in body composition and plasma lipids in response to a high-carbohydrate diet, Archer, W.R., Lamarche, B., Dériaz, O., Landry, N., Corneau, L., Després, J.-P., Bergeron, J., Couture, P., Bergeron, N., Obesity Research, 2003, 10.1038/oby.2003.135
  • Dietary fat intake determines the effect of a common polymorphism in the hepatic lipase gene promoter on high-density lipoprotein metabolism: Evidence of a strong dose effect in this gene-nutrient interaction in the Framingham study, Ordovas, J.M., Corella, D., Demissie, S., Cupples, L.A., Couture, P., Coltell, O., Wilson, P.W.F., Schaefer, E.J., Tucker, K.L., Circulation, 2002, 10.1161/01.CIR.0000036597.52291.C9
  • Influence of LDL receptor gene mutation and apo E polymorphism on lipoprotein response to simvastatin treatment among adolescents with heterozygous familial hypercholesterolemia, Vohl, M.-C., Szots, F., Lelièvre, M., Lupien, P., Bergeron, J., Gagné, C., Couture, P., Atherosclerosis, 2002, 10.1016/S0021-9150(01)00584-6
  • Association of the Sst-I polymorphism at the APOC3 gene locus with variations in lipid levels, lipoprotein subclass profiles and coronary heart disease risk: The Framingham offspring study, Russo, G.T., Meigs, J.B., Cupples, L.Adrienne, Demissie, S., Otvos, J.D., Wilson, P.W.F, Lahoz, C., Cucinotta, D., Couture, P., Mallory, T., Schaefer, E.J., Ordovas, J.M., Atherosclerosis, 2001, 10.1016/S0021-9150(01)00409-9
  • Evidence of a founder effect for the protein C gene 3363 inserted C mutation in thrombophilic pedigrees of French origin, Couture, P., Bovill, E.G., Demers, C., Simard, J., Delage, R., Scott, B.T., Valliere, J.E., Callas, P.W., Jomphe, M., Rosendaal, F.R., Aiach, M., Long, G.L., Thrombosis and Haemostasis, 2001
  • Absence of association between genetic variation in the promoter of the microsomal triglyceride transfer protein gene and plasma lipoproteins in the Framingham Offspring Study, Couture, P., Otvos, J.D., Cupples, L.A., Wilson, P.W.F., Schaefer, E.J., Ordovas, J.M., Atherosclerosis, 2000, 10.1016/S0021-9150(99)00281-6
  • Association of the C-514T polymorphism in the hepatic lipase gene with variations in lipoprotein subclass profiles: The Framingham Offspring Study, Couture, P., Otvos, J.D., Cupples, L.A., Lahoz, C., Wilson, P.W.F., Schaefer, E.J., Ordovas, J.M., Arteriosclerosis, Thrombosis, and Vascular Biology, 2000, 10.1161/01.ATV.20.3.815
  • 3. High-density lipoprotein as a coronary heart disease risk factor and gene mutations affecting high-density lipoprotein cholesterol levels: Results from the Framingham Heart Study, Schaefer, E.J., Lahoz, C., Couture, P., Cendoroglo, M., Russo, G., Cupples, L.A., Wilson, P.W.F., Ordovas, J.M., Atherosclerosis, 1999, 10.1016/S0021-9150(99)00225-7
  • Association of the A-204C polymorphism in the cholesterol 7α- hydroxylase gene with variations in plasma low density lipoprotein cholesterol levels in the Framingham Offspring Study, Couture, P., Otvos, J.D., Cupples, L.A., Wilson, P.W.F., Schaefer, E.J., Ordovas, J.M., Journal of Lipid Research, 1999
  • Contribution of receptor negative versus receptor defective mutations in the LDL-receptor gene to angiographically assessed coronary artery disease among young (25-49 years) versus middle-aged (50-64 years) men, Gaudet, D., Vohl, M.-C., Couture, P., Moorjani, S., Tremblay, G., Perron, P., Gagné, C., Després, J.-P., Atherosclerosis, 1999, 10.1016/S0021-9150(98)00268-8
  • Ethical issues in molecular screening for heterozygous familial hypercholesterolemia: The complexity of dealing with genetic susceptibility to coronary artery disease, Gaudet, D., Gagne, C., Perron, P., Couture, P., Tonstad, S., Community Genetics, 1999, 10.1159/000016176
  • Expression of the androgen metabolizing enzyme UGT2B15 in adipose tissue and relative expression measurement using a competitive RT-PCR method, Tchernof, A., Lévesque, E., Beaulieu, M., Couture, P., Després, J.-P., Hum, D.W., Bélanger, A., Clinical Endocrinology, 1999, 10.1046/j.1365-2265.1999.00709.x
  • Fine mapping of low-density lipoprotein receptor gene by genetic linkage on chromosome 19p13.1-p13.3 and study of the founder effect of four French Canadian low-density lipoprotein receptor gene mutations, Couture, P., Morissette, J., Gaudet, D., Vohl, M.-C., Gagné, C., Bergeron, J., Després, J.-P., Simard, J., Atherosclerosis, 1999, 10.1016/S0021-9150(98)00267-6
  • Association of specific LDL receptor gene mutations with differential plasma lipoprotein response to simvastatin in young French Canadians with heterozygous familial hypercholesterolemia, Couture, P., Brun, L.D., Szots, F., Lelièvre, M., Gaudet, D., Després, J.-P., Simard, J., Lupien, P.J., Gagné, C., Arteriosclerosis, Thrombosis, and Vascular Biology, 1998, 10.1161/01.ATV.18.6.1007
  • Identification of three mutations in the lowdensity lipoprotein receptor gene causing familial hypercholesterolemia among french canadians, Couture, P., Vohl, M.C., Gagné, C., Gaudet, D., Torres, A.L., Lupien, P.J., Després, J.P., Labrie, F., Simard, J., Moorjani, S., Human Mutation, 1998, 10.1002/humu.1380110173
  • Severe debilitating xanthomatosis in a French-Canadian patient with heterozygous familial hypercholesterolemia, Carpentier, A., Couture, P., Brun, L.-D., Gagné, C., Endocrinologist, 1998
  • Type I protein C deficiency in French Canadians: Evidence of a founder effect and association of specific protein C gene mutations with plasma protein C levels, Couture, P., Demers, C., Morissette, J., Delage, R., Jomphe, M., Couture, L., Simard, J., Thrombosis and Haemostasis, 1998
  • Geographic distribution of French-Canadian low-density lipoprotein receptor gene mutations in the Province of Quebec, Vohl, M.-C., Moorjani, S., Roy, M., Gaudet, D., Torres, A.L., Minnich, A., Gagné, C., Tremblay, G., Lambert, M., Bergeron, J., Couture, P., Perron, P., Blaichman, S., Brun, L.-D., Davignon, J., Lupien, P.J., Després, J.-P., Clinical Genetics, 1997
  • Hyperlipidemia as the first biochemical manifestation of primary hepatic amyloidosis, Couture, P., LeBlanc, F., Gagnon, P., Gagnon, O., Gagné, C., American Journal of Gastroenterology, 1997
  • Rapid restriction fragment analysis for screening four point mutations of the Low‐density lipoprotein receptor gene in French Canadians, Vohl, M.‐C., Couture, P., Moorjani, S., Torres, A.L., Gagné, C., Després, J.‐P., Lupien, P.J., Labrie, F., Simard, J., Human Mutation, 1995, 10.1002/humu.1380060307
  • Detection of a novel mutation (stop 468) in exon 10 of the low-density lipoprotein receptor gene causing familial hypercholesterolemia among french canadians, Simard, J., Moorjani, S., Vohl, M.-C., Couture, P., Torres, A.L., Gagné, C., Després, J.-P., Labrie, F., Lupien, P.J., Human Molecular Genetics, 1994, 10.1093/hmg/3.9.1689
  • Androgen receptor-mediated stimulation of 17β-hydroxysteroid dehydrogenase activity by dihydrotestosterone and medroxyprogesterone acetate in zr-75-1 human breast cancer cells, Couture, P., Theriault, C., Simardj, J., Labrie, F., Endocrinology, 1993, 10.1210/endo.132.1.8380373

Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2009
  • Louis-Charles Desjardins - Maitrîse avec mémoire - En cours
  • Catherine Goulet - Maitrîse avec mémoire - 2011/05
  • Audrey Cyr - Maitrîse avec mémoire - 2012/09
  • Geneviève Nolet - Maitrîse avec mémoire - 2012/09
  • Lisa Baril-Gravel - Maitrîse avec mémoire - 2012/09
  • Caroline Richard - Doctorat - 2013/09
  • Jean-Philippe Drouin-Chartier - Maitrîse avec mémoire - 2014/05
  • Marie-Eve Labonté - Doctorat - 2015/01
  • Myriam Leclerc - Maitrîse avec mémoire - 2016/01
  • Maude Tessier Grenier - Maitrîse avec mémoire - 2017/01
  • Didier Brassard - Maitrîse avec mémoire - 2017/01
  • Maryka Rancourt-Bouchard - Maitrîse avec mémoire - 2018/09
  • Janie Allaire - Doctorat - 2019/01
  • Catherine Lalande - Maitrîse avec mémoire - 2020/05

Encadrement d'étudiant(e)s pour les programmes suivants :

Disponibilité d'encadrement d'étudiant(e)s

Ce (cette) professeur(e) est présentement à la recherche d'étudiant(e)s.

Envoyer un courriel
*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.

Direction et personnes-ressources

Vice-décanat à la recherche et aux études supérieures
Pavillon Ferdinand-Vandry
Université Laval
1050, avenue de la Médecine,  local 4645
Québec, Québec G1V 0A6
Canada

Renseignements - Secrétariat :
vdres@fmed.ulaval.ca
Téléphone 418 656-2690

Jacques Simard
Vice-doyen à la recherche et aux études supérieures
vice-doyen.recherche-et-etudes-superieures@fmed.ulaval.ca

Louise Laperrière
Adjointe au vice-doyen à la recherche et aux études supérieures
louise.laperriere@fmed.ulaval.ca 

Volet recherche
Gestion financière
Volet études aux cycles supérieurs