Découvrez nos professeurs et professeures!

Michel Maziade

Médecin clinicien enseignant titulaire

Michel Maziade
Centre thématique de recherche en neurosciences
VITAM – Centre de recherche en santé durable
Centre de recherche CERVO
Centre de recherche en santé durable (VITAM)
Partager la fiche :

Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Bioinformatique / données massives (big data)
Neurosciences et santé mentale
Pédagogie des sciences de la santé
Santé des populations et pratiques optimales en santé
Soins et services de première ligne
Transfert des connaissances

Domaines et intérêts de recherche du (de la) professeur(e) :

Génétique humaine
Neurosciences, santé mentale et toxicomanies
Santé de la mère, des enfants et des adolescents
Santé des populations
Santé différentielle des sexes
Services de santé

Projets de recherche

  • Altered retinal response as a neurobiological component of the risk trajectory and of the developmental pathophysiology of major psychiatric disorders - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2022-04-01 au 2027-03-31
  • Exploring the role of rare genetic variations in the risk for schizophrenia and bipolar disorder in patients from multi-affected kindreds in the Quebec founder population - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2021-04-01 au 2025-03-31
  • Institut universitaire de première ligne en santé et services sociaux. - Fonds de recherche du Québec - Société et culture - Soutien aux infrastructures de recherche des Instituts et des Centres affiliés universitaires du secteur social, co-chercheur - 2014-04-01 au 2023-03-31
  • Intercepting the "childhood risk syndrome" of schizophrenia and mood disorders along the developmental trajectory: A preclinical staging of children and adolescents at genetic risk - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2017-04-01 au 2022-03-31
  • Télé-NEUROS (Nouvel Environnement Universitaire de Recherche Orchestrée en Santé mentale et cognitive: une télé initiative) - CIUSSS - CN - CIRRIS, Université Laval - Fonds internes, CIUSSS - CN - CERVO, co-chercheur - 2020-10-20 au 2021-03-31
  • Neurophotonics Initiative, phase II - CHU de Québec – Université Laval – CHUL, Ministère de la Santé et des Services sociaux, CIUSSS - CN - CERVO, Université Laval - Fonds internes, Fondation Canadienne pour l'innovation (La), Ministère de l'Enseignement supérieur, de la Recherche, de la Science - Fonds d'innovation (FI), co-chercheur - 2015-10-01 au 2021-03-30
  • Investigating electroretinography(ERG) as a new method for predicting conversion to psychosis in youth at clinical high risk. - Instituts de recherche en santé du Canada - Subvention de fonctionnement, co-chercheur - 2015-07-01 au 2020-06-30


  • Uptrend in distress and psychiatric symptomatology in pregnant women during the coronavirus disease 2019 pandemic, Nicolas Berthelot, Roxanne Lemieux, Julia Garon‐Bissonnette, Christine Drouin‐Maziade, Élodie Martel, Michel Maziade, Acta Obstetricia et Gynecologica Scandinavica, 2020, 10.1111/aogs.13925
  • Retinal function anomalies in young offspring at genetic risk of schizophrenia and mood disorder: The meaning for the illness pathophysiology, Anne-Marie Gagné, Isabel Moreau, Isabelle St-Amour, Pierre Marquet, Michel Maziade, Schizophrenia Research, 2020, 10.1016/j.schres.2019.06.021
  • The place of the retina in psychiatry: Uniting neurobiological and neurodevelopmental research with clinical research in psychiatric disorders, Michel Maziade, Steven M. Silverstein, Schizophrenia Research, 2020, 10.1016/j.schres.2020.03.028
  • Defective compensation over early dysneurogenesis in schizophrenia and mood disorder, Michel Maziade, Thomas Paccalet, Elsa Gilbert, Schizophrenia Research, 2018, 10.1016/j.schres.2017.06.041
  • Liability indicators aggregate many years before transition to illness in offspring descending from kindreds affected by schizophrenia or bipolar disorder, Thomas Paccalet, Elsa Gilbert, Nicolas Berthelot, Pierre Marquet, Valérie Jomphe, Daphné Lussier, Roch-Hugo Bouchard, Denis Cliche, Nathalie Gingras, Michel Maziade, Schizophrenia Research, 2016, 10.1016/j.schres.2016.04.038
  • Common Childhood Determinants of Psychiatric and Cardiovascular Disorders Call for Common Prevention and Clinical Research., Maziade M, Paccalet T, 2013, 10.1001/jamapediatrics.2013.3871
  • Cluster analysis of cognitive deficits may mark heterogeneity in schizophrenia in terms of outcome and response to treatment., Gilbert E, Mérette C, Jomphe V, Emond C, Rouleau N, Bouchard RH, Roy MA, Paccalet T, Maziade M, 2013
  • The brain through the retina: The flash electroretinogram as a tool to investigate psychiatric disorders., Lavoie J, Maziade M, Hébert M, 2013, 10.1016/j.pnpbp.2013.09.020
  • Follow-up of a major psychosis linkage site in 13q13-q14 reveals significant association in both case-control and family samples., Bureau A, Chagnon YC, Croteau J, Fournier A, Roy MA, Paccalet T, Mérette C, Maziade M, 2013, 10.1016/j.biopsych.2013.03.004
  • Putative Risk Factors in Developmental Dyslexia: A Case-Control Study of Italian Children., Mascheretti S, Marino C, Simone D, Quadrelli E, Riva V, Cellino MR, Maziade M, Brombin C, Battaglia M, 2013
  • A protective-compensatory model may reconcile the genetic and the developmental findings in schizophrenia., Maziade M, Paccalet T, 2013, 10.1016/j.schres.2012.12.022
  • Symptom dimensions as alternative phenotypes to address genetic heterogeneity in schizophrenia and bipolar disorder., Labbe A, Bureau A, Moreau I, Roy MA, Chagnon Y, Maziade M, Merette C, 2012, 10.1038/ejhg.2012.67
  • Detection of phenotype modifier genes using two-locus linkage analysis in complex disorders such as major psychosis., Bureau A, Croteau J, Mérette C, Fournier A, Chagnon YC, Roy MA, Maziade M, 2012, 10.1159/000341392
  • Principal components of heritability for high dimension quantitative traits and general pedigrees., Oualkacha K, Labbe A, Ciampi A, Roy MA, Maziade M, 2012, 10.2202/1544-6115.1711
  • Verbal and visual memory impairments among young offspring and healthy adult relatives of patients with schizophrenia and bipolar disorder: selective generational patterns indicate different developmental trajectories., Maziade M, Rouleau N, Mérette C, Cellard C, Battaglia M, Marino C, Jomphe V, Gilbert E, Achim A, Bouchard RH, Paccalet T, Paradis ME, Roy MA, 2011, 10.1093/schbul/sbq026
  • How prevalent are anxiety disorders in schizophrenia? A meta-analysis and critical review on a significant association., Achim AM, Maziade M, Raymond E, Olivier D, Mérette C, Roy MA, 2011, 10.1093/schbul/sbp148
  • Animal models of human anxiety disorders: reappraisal from a developmental psychopathology vantage point., Lampis V, Maziade M, Battaglia M, 2011, 10.1203/PDR.0b013e318212b42e
  • Young offspring at genetic risk of adult psychoses: the form of the trajectory of IQ or memory may orient to the right dysfunction at the right time., Maziade M, Rouleau N, Cellard C, Battaglia M, Paccalet T, Moreau I, Gagnon V, Gingras N, Marino C, Gilbert E, Roy MA, Mérette C, 2011, 10.1371/journal.pone.0019153
  • Schizophrenia patients with polydipsia and water intoxication are characterized by greater severity of psychotic illness and a more frequent history of alcohol abuse., Poirier S, Legris G, Tremblay P, Michea R, Viau-Guay L, Mérette C, Bouchard RH, Maziade M, Roy MA, 2010, 10.1016/j.schres.2009.12.036
  • An examination of the relative contribution of saturation and selective attention to memory deficits in patients with recent-onset schizophrenia and their unaffected parents., Cellard C, Lefèbvre AA, Maziade M, Roy MA, Tremblay S, 2010, 10.1037/a0018397
  • Retinal response to light in young nonaffected offspring at high genetic risk of neuropsychiatric brain disorders., Hébert M, Gagné AM, Paradis ME, Jomphe V, Roy MA, Mérette C, Maziade M, 2010, 10.1016/j.biopsych.2009.08.016
  • Familiarity and recollection processes in patients with recent-onset schizophrenia and their unaffected parents., Lefèbvre AA, Cellard C, Tremblay S, Achim A, Rouleau N, Maziade M, Roy MA, 2010, 10.1016/j.psychres.2009.01.007
  • Atomoxetine and neuropsychological function in children with attention-deficit/hyperactivity disorder: results of a pilot study., Maziade M, Rouleau N, Lee B, Rogers A, Davis L, Dickson R, 2009, 10.1089/cap.2008.0166
  • Shared neurocognitive dysfunctions in young offspring at extreme risk for schizophrenia or bipolar disorder in eastern quebec multigenerational families., Maziade M, Rouleau N, Gingras N, Boutin P, Paradis ME, Jomphe V, Boutin J, Létourneau K, Gilbert E, Lefebvre AA, Doré MC, Marino C, Battaglia M, Mérette C, Roy MA, 2009, 10.1093/schbul/sbn058
  • Chromosome 13q13-q14 locus overlaps mood and psychotic disorders: the relevance for redefining phenotype., Maziade M, Chagnon YC, Roy MA, Bureau A, Fournier A, Mérette C, 2009, 10.1038/ejhg.2008.268
  • Effects of phonological and semantic cuing on encoding and retrieval processes in adolescent psychosis., Doré MC, Caza N, Gingras N, Maziade M, Rouleau N, 2009, 10.1080/13803390802317567
  • A new strategy for linkage analysis under epistasis taking into account genetic heterogeneity., Bureau A, Mérette C, Croteau J, Fournier A, Chagnon YC, Roy MA, Maziade M, 2009, 10.1159/000228921
  • Replication of linkage with bipolar disorder on chromosome 16p in the Eastern Quebec population., Mérette C, Roy MA, Bureau A, Fournier A, Emond C, Cliche D, Jomphe V, Chagnon YC, Maziade M, 2008, 10.1002/ajmg.b.30673
  • Decomposing the autism phenotype into familial dimensions., Szatmari P, Mérette C, Emond C, Zwaigenbaum L, Jones MB, Maziade M, Roy MA, Palmour R, 2008, 10.1002/ajmg.b.30561
  • Gene-environment interaction and behavioral disorders: a developmental perspective based on endophenotypes., Battaglia M, Marino C, Maziade M, Molteni M, D'Amato F, 2008
  • Informative phenotypes for genetic studies of psychiatric disorders., Szatmari P, Maziade M, Zwaigenbaum L, Mérette C, Roy MA, Joober R, Palmour R, 2007, 10.1002/ajmg.b.30426
  • Schizophrenia and Bipolar Disorder: Linkage on Chromosomes 5 and 11, , 2006, 10.1038/npg.els.0005226
  • A pilot feasibility study of an extension of the acquaintanceship recruitment procedure in recent-onset psychosis., Lehoux C, Lefebvre AA, Létourneau K, Viau H, Gosselin D, Szatmari P, Bouchard RH, Maziade M, Roy MA, 2005, 10.1097/01.nmd.0000172680.18302.80
  • A factor analysis of the Strauss and Carpenter revised outcome criteria scale: a validation of the French translation., Poirier S, Bureau V, Lehoux C, Bouchard RH, Maziade M, Pelletier S, René L, Trépanier J, Emond C, Mérette C, Roy MA, 2004, 10.1097/01.nmd.0000146880.91895.50
  • [Genetics of schizophrenia and bipolar disorder: recent success of linkage studies with evidence of specific and shared susceptibility loci]., Maziade M, Mérette C, Chagnon YC, Roy MA, 2003
  • Fine motor dexterity is correlated to social functioning in schizophrenia., Lehoux C, Everett J, Laplante L, Emond C, Trépanier J, Brassard A, René L, Cayer M, Mérette C, Maziade M, Roy MA, 2003, 10.1016/S0920-9964(02)00327-4
  • A pilot neuropsychological study of Kraepelinian and non-Kraepelinian schizophrenia., Roy MA, Lehoux C, Emond C, Laplante L, Bouchard RH, Everett J, Mérette C, Maziade M, 2003, 10.1016/S0920-9964(02)00481-4
  • Quantifying dimensions in autism: a factor-analytic study., Szatmari P, Mérette C, Bryson SE, Thivierge J, Roy MA, Cayer M, Maziade M, 2002, 10.1097/00004583-200204000-00020
  • Chromosome 1q12-q22 linkage results in eastern Quebec families affected by schizophrenia., Maziade M, Fournier A, Phaneuf D, Cliche D, Fournier JP, Roy MA, Mérette C, 2002, 10.1002/ajmg.1616
  • Facfors associated with the reliability of the best-estimate diagnostic procedure, , 1997, 10.1016/s0920-9964(97)82017-8
  • Very poor outcome schizophrenia: A pilot study, , 1997, 10.1016/s0920-9964(97)82741-7
  • Extreme Temperament and Diagnosis, , 1990, 10.1001/archpsyc.1990.01810170077011
  • Le tempérament de l’enfant, les différences individuelles et les forces environnementales, , 1911, 10.7202/030183ar

Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2009
  • Geneviève Gaudreau - Doctorat - 2014/01
  • Rossana Ganzola - Doctorat - 2017/01
*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.