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Chaire de recherche du Canada en Cellules Souches et Génie Tissulaire- Instituts de recherche en santé du Canada - Chaires de recherche du Canada - Fonctionnement, chercheur principal - 2022-01-01 au 2028-12-31
Régénération de la peau humaine : Une peau reconstruite par génie tissulaire pigmentée produite plus rapidement pour traiter les patients grands brûlés- Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2022-07-01 au 2027-06-30
Tissue-engineered solutions for uro-genital reconstruction, and replacing banned synthetic meshes- Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2021-10-01 au 2026-09-30
Fonds institutionnel d'exploitation des infrastructures pour l'Université Laval- Fondation Canadienne pour l'innovation (La) - Fonds d'exploitation des infrastructures (FEI), co-chercheur - 2002-04-01 au 2025-03-31
PSO du Gvt du Québec:Salles GMP pour la consolidation de tissus en médecine régénératrice. Qui va avec FCI: A cGMP facilily for Personalized Tissus Engineering - CHU de Québec – Université Laval – CHUL - Développement de la recherche (FC), co-chercheur - 2022-03-30 au 2025-03-30
Combining tissue-engineered skin with ex vivo gene therapy correction to develop a treatment for epidermolysis bullosa- Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC) - Réseau de centres d'excellence (RCE), chercheur principal - 2022-04-01 au 2024-03-31
Chaire de recherche sur les organes reconstruits en laboratoire et leurs applications cliniques- Fondation de l'Université Laval - Chaires de recherche sans organismes subventionnaires, chercheur principal - 2013-05-01 au 2023-08-12
La réponse immunitaire aux peaux reconstruites avec des cellules allogéniques.- Fonds de recherche du Québec - Santé - Réseaux thématiques de recherche, chercheur principal - 2022-04-01 au 2023-03-31
Effet de la lumière sur les peaux reconstruites - CHU de Québec – Université Laval – CHUL - Développement de la recherche (FC), chercheur principal - 2022-03-30 au 2023-03-29
Cultured epithelial corneal autografts for the treatment of canadians with limbal stem cell deficiency- Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC) - Réseau de centres d'excellence (RCE), chercheur principal - 2020-01-01 au 2023-01-31
Recherche en vue de développer un traitement pour les patients atteints d'épidermolyse bulleuse dystrophique- Fondation du CHU de Québec, chercheur principal - 2021-09-14 au 2022-09-13
Les cellules souches épithéliales et le génie tissulaire : de la recherche fondamentale à la recherche clinique.- Instituts de recherche en santé du Canada - Subventions Fondation, chercheur principal - 2015-07-01 au 2022-06-30
Soutien à la recherche dans le domaine des maladies auto-immunes et de la cicatrisation- Fondation de l'Université Laval, chercheur principal - 2016-04-01 au 2022-03-31
Monitoring expression of the transcription factors Sp1 and NFI as markers of cell quality in human corneal epithelial cells cultured on different cell carriers- Fonds de recherche du Québec - Santé - Réseaux thématiques de recherche, co-chercheur - 2021-02-01 au 2022-03-31
The Canadian National Transplant Research Program : Increasing Donation and Improving Transplantation Outcomes- Instituts de recherche en santé du Canada - Autre : Recherche sur la transplantation, University of Alberta, co-chercheur - 2013-04-01 au 2022-03-31
Tissue-engineered solutions for uro-genital reconstruction, and replacing banned synthetic meshes- Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2021-03-01 au 2022-02-28
Towards an epidermolysis bullosa clinical trial with tissue-engineered skin after ex vivo gene therapy correction- Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC), Fondation du CHU de Québec, Fonds de recherche du Québec - Santé - Réseau de centres d'excellence (RCE), chercheur principal - 2020-08-01 au 2022-02-28
Self-Assembly Skin Substitutes (SASS) for the treatment of acute wounds of Canadian burn patients- Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC) - Réseau de centres d'excellence (RCE), co-chercheur - 2020-01-01 au 2022-01-31
Chaire de recherche du Canada EN CELLULES SOUCHES ET GÉNIE TISSULAIRE- Instituts de recherche en santé du Canada - Chaires de recherche du Canada - Fonctionnement, chercheur principal - 2015-01-01 au 2021-12-31
Évaluation de la qualité, de la structure et des propriétés fonctionnelles des peaux reconstruites par génie tissulaire- MITACS Inc. - Accélération Québec (MITACS/MEIE), chercheur principal - 2019-09-01 au 2021-08-31
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Publications
Structural and Functional Validation of a Full-Thickness Self-Assembled Skin Equivalent for Disease Modeling, Bo Ram Mok, Su-Ji Shon, Aram Kim, Carolyne Simard-Bisson, Israël Martel, Lucie Germain, Dong Hyun Kim, Jung U Shin, Pharmaceutics, 2022, 10.3390/pharmaceutics14061211
Tie-Over Bolster Pressure Dressing Improves Outcomes of Skin Substitutes Xenografts on Athymic Mice, Andréanne Cartier, Martin A. Barbier, Danielle Larouche, Amélie Morissette, Ariane Bussières, Livia Montalin, Chanel Beaudoin Cloutier, Lucie Germain, International Journal of Molecular Sciences, 2022, 10.3390/ijms23105507
Contribution of the Transcription Factors Sp1/Sp3 and AP-1 to Clusterin Gene Expression during Corneal Wound Healing of Tissue-Engineered Human Corneas, Christelle Gross, Gaëtan Le-Bel, Pascale Desjardins, Manel Benhassine, Lucie Germain, Sylvain L. Guérin, International Journal of Molecular Sciences, 2021, 10.3390/ijms222212426
Biofabrication and preclinical evaluation of a large-sized human self-assembled skin substitute, Kawecki, F., Mayrand, D., Ayoub, A., Attiogbe, É., Germain, L., Auger, F.A., Moulin, V.J., Biomedical Materials (Bristol), 2021, 10.1088/1748-605X/abbdbe
The Human Tissue-Engineered Cornea (hTEC): Recent Progress, Louis-Philippe Guérin, Gaëtan Le-Bel, Pascale Desjardins, Camille Couture, Elodie Gillard, Elodie Boisselier, Richard Bazin, Lucie Germain, Sylvain L. Guérin, International Journal of Molecular Sciences, 2021, 10.3390/ijms22031291
Human Organ-Specific 3D Cancer Models Produced by the Stromal Self-Assembly Method of Tissue Engineering for the Study of Solid Tumors, Roy, V., Magne, B., Vaillancourt-Audet, M., Blais, M., Chabaud, S., Grammond, E., Piquet, L., Fradette, J., Laverdière, I., Moulin, V.J., Landreville, S., Germain, L., Auger, F.A., Gros-Louis, F., Bolduc, S., BioMed Research International, 2020, 10.1155/2020/6051210
Limb salvage after aneurysmal degeneration of a cryopreserved vein allograft: Searching the autologous veins of the arm is worth the effort,Sauvetage de membre après dégénération anévrysmale d'une homogreffe veineuse : l'effort de recherche des veines autologues du bras est justifié, Tong, Y., Febrer, G., Mao, J., Wawryko, P., Mao, Y., Le-Bel, G., How, D., Philippe, E., Zhou, T., Zhang, Z., Wang, L., Germain, L., Guidoin, R., Morphologie, 2020, 10.1016/j.morpho.2020.05.001
Peel Test to Assess the Adhesion Strength of the Dermal-Epidermal Junction in Tissue-Engineered Skin, Larose, A.E., Dakiw-Piaceski, A., Barbier, M.A., Larouche, D., Gauvin, R., Caruso, M., Pope, E., Germain, L., Tissue Engineering - Part C: Methods, 2020, 10.1089/ten.tec.2019.0268
The self-assembly approach as a tool for the tissue engineering of a bi-lamellar human cornea, Le-Bel, G., Desjardins, P., Couture, C., Germain, L., Guérin, S.L., Methods in Molecular Biology, 2020, 10.1007/978-1-0716-0599-8_8
Irradiated Human Fibroblasts as a Substitute Feeder Layer to Irradiated Mouse 3T3 for the Culture of Human Corneal Epithelial Cells: Impact on the Stability of the Transcription Factors Sp1 and NFI, Gaëtan Le-Bel, Sergio Cortez Ghio, Louis-Philippe Guérin, Francis Bisson, Lucie Germain, Sylvain L. Guérin, International Journal of Molecular Sciences, 2019, 10.3390/ijms20246296
Contribution of the WNK1 kinase to corneal wound healing using the tissue-engineered human cornea as an in vitro model, Desjardins, P., Couture, C., Germain, L., Guérin, S.L., Journal of Tissue Engineering and Regenerative Medicine, 2019, 10.1002/term.2912
Donkey pericardium compares favorably with commercial xenopericardia used in the manufacture of transcatheter heart valves, Mao, J., Rassoli, A., Tong, Y., Rouse, E.N., Le-Bel, G., How, D., Germain, L., Fatouraee, N., Zhang, Z., Reed, R.R., Guidoin, R., Artificial Organs, 2019, 10.1111/aor.13503
Generation of High-Titer Self-Inactivated γ-Retroviral Vector Producer Cells, Ghani, K., Boivin-Welch, M., Roy, S., Dakiw-Piaceski, A., Barbier, M., Pope, E., Germain, L., Caruso, M., Molecular Therapy - Methods and Clinical Development, 2019, 10.1016/j.omtm.2019.05.013
Grafting of an autologous tissue-engineered human corneal epithelium to a patient with limbal stem cell deficiency (LSCD), Le-Bel, G., Guérin, L.-P., Carrier, P., Mouriaux, F., Germain, L., Guérin, S.L., Bazin, R., American Journal of Ophthalmology Case Reports, 2019, 10.1016/j.ajoc.2019.100532
Immune tolerance of tissue-engineered skin produced with allogeneic or xenogeneic fibroblasts and syngeneic keratinocytes grafted on mice, Goyer, B., Larouche, D., Kim, D.H., Veillette, N., Pruneau, V., Bernier, V., Auger, F.A., Germain, L., Acta Biomaterialia, 2019, 10.1016/j.actbio.2019.04.010
Impact of ultraviolet radiation on dermal and epidermal DNA damage in a human pigmented bilayered skin substitute, Goyer, B., Pereira, U., Magne, B., Larouche, D., Kearns-Turcotte, S., Rochette, P.J., Martin, L., Germain, L., Journal of Tissue Engineering and Regenerative Medicine, 2019, 10.1002/term.2959
Isolation and culture of human keratinocytes, Cortez Ghio, S., Le-Bel, G., Lavoie, A., Larouche, D., Germain, L., Methods in Molecular Biology, 2019, 10.1007/978-1-4939-9473-1_1
Qualitatively monitoring binding and expression of the transcription factors Sp1 and NFI as a useful tool to evaluate the quality of primary cultured epithelial stem cells in tissue reconstruction, Le-Bel, G., Cortez Ghio, S., Larouche, D., Germain, L., Guérin, S.L., Methods in Molecular Biology, 2019, 10.1007/7651_2018_153
The Red Kangaroo pericardium as a material source for the manufacture of percutaneous heart valves,Le péricarde du kangourou roux comme source d'approvisionnement de matériel pour la fabrication de valves cardiaques percutanées, Meng, S., Mao, J., Rouse, E.N., Le-Bel, G., Bourget, J.M., Reed, R.R., Philippe, E., How, D., Zhang, Z., Germain, L., Guidoin, R., Morphologie, 2019, 10.1016/j.morpho.2018.12.004
Specialized Living Wound Dressing Based on the Self-Assembly Approach of Tissue Engineering, Laurence Cantin-Warren, Rina Guignard, Sergio Cortez Ghio, Danielle Larouche, François A. Auger, Lucie Germain, Journal of Functional Biomaterials, 2018, 10.3390/jfb9030053
Are the Effects of the Cholera Toxin and Isoproterenol on Human Keratinocytes’ Proliferative Potential Dependent on Whether They Are Co-Cultured with Human or Murine Fibroblast Feeder Layers?, , International Journal of Molecular Sciences, 2018, 10.3390/ijms19082174
Autologous bilayered self-assembled skin substitutes (Sasss) as permanent grafts: A case series of 14 severely burned patients indicating clinical effectiveness, Germain, L., Larouche, D., Nedelec, B., Perreault, I., Duranceau, L., Bortoluzzi, P., Cloutier, C.B., Genest, H., Caouette-Laberge, L., Dumas, A., Bussière, A., Boghossian, E., Kanevsky, J., Leclerc, Y., Lee, J., Nguyen, M.T., Bernier, V., Knoppers, B.M., Moulin, V.J., Auger, F.A., European Cells and Materials, 2018, 10.22203/eCM.v036a10
Enhanced wound healing of tissue-engineered human corneas through altered phosphorylation of the CREB and AKT signal transduction pathways, Couture, C., Desjardins, P., Zaniolo, K., Germain, L., Guérin, S.L., Acta Biomaterialia, 2018, 10.1016/j.actbio.2018.04.021
The presence of a feeder layer improves human corneal endothelial cell proliferation by altering the expression of the transcription factors Sp1 and NFI, Le-Bel, G., Giasson, C.J., Deschambeault, A., Carrier, P., Germain, L., Guérin, S.L., Experimental Eye Research, 2018, 10.1016/j.exer.2018.07.009
Translating the combination of gene therapy and tissue engineering for treating recessive dystrophic epidermolysis bullosa, Piaceski, A.D., Larouche, D., Ghani, K., Bisson, F., Ghio, S.C., Larochelle, S., Moulin, V.J., Caruso, M., Germain, L., European Cells and Materials, 2018, 10.22203/eCM.v035a06
A Role for DLK in Microtubule Reorganization to the Cell Periphery and in the Maintenance of Desmosomal and Tight Junction Integrity, Simard-Bisson, C., Bidoggia, J., Larouche, D., Guérin, S.L., Blouin, R., Hirai, S.-I., Germain, L., Journal of Investigative Dermatology, 2017, 10.1016/j.jid.2016.07.035
Correlation between structural changes and acute thrombogenicity in transcatheter pericardium valves after crimping and balloon deployment,Corrélation entre les altérations structurales et la thrombogénicité aiguë des valves percutanées en péricarde après sertissage et expansion, Bourget, J.-M., Zegdi, R., Lin, J., Wawryko, P., Merhi, Y., Convelbo, C., Mao, J., Fu, Y., Xu, T., Merkel, N.O., Wang, L., Germain, L., Zhang, Z., Guidoin, R., Morphologie, 2017, 10.1016/j.morpho.2016.06.003
Expression of C4.4A in an in Vitro Human Tissue-Engineered Skin Model, Jacobsen, B., Larouche, D., Rochette-Drouin, O., Ploug, M., Germain, L., BioMed Research International, 2017, 10.1155/2017/2403072
In Vivo Evaluation and Imaging of a Bilayered Self-Assembled Skin Substitute Using a Decellularized Dermal Matrix Grafted on Mice, Beaudoin Cloutier, C., Goyer, B., Perron, C., Guignard, R., Larouche, D., Moulin, V.J., Germain, L., Gauvin, R., Auger, F.A., Tissue Engineering - Part A, 2017, 10.1089/ten.tea.2016.0296
Microstructural alterations owing to handling of bovine pericardium to manufacture bioprosthetic heart valves: A potential risk for cusp dehiscence,Modifications microstructurales causées par la manipulation du péricarde bovin pour monter des bioprothèses valvulaires : une cause potentielle de déhiscence cuspide, Mao, J., Wang, Y., Philippe, E., Cianciulli, T., Vesely, I., How, D., Bourget, J.-M., Germain, L., Zhang, Z., Guidoin, R., Morphologie, 2017, 10.1016/j.morpho.2017.03.003
Microstructured human fibroblast-derived extracellular matrix scaffold for vascular media fabrication, Bourget, J.-M., Laterreur, V., Gauvin, R., Guillemette, M.D., Miville-Godin, C., Mounier, M., Tondreau, M.Y., Tremblay, C., Labbé, R., Ruel, J., Auger, F.A., Veres, T., Germain, L., Journal of Tissue Engineering and Regenerative Medicine, 2017, 10.1002/term.2146
Tissue-Engineered Tubular Heart Valves Combining a Novel Precontraction Phase with the Self-Assembly Method, Picard-Deland, M., Ruel, J., Galbraith, T., Tremblay, C., Kawecki, F., Germain, L., Auger, F.A., Annals of Biomedical Engineering, 2017, 10.1007/s10439-016-1708-1
27.12 MHz Radiofrequency Ablation for Benign Cutaneous Lesions, Kim, D.H., Hyun, D.J., Piquette, R., Beaumont, C., Germain, L., Larouche, D., BioMed Research International, 2016, 10.1155/2016/6016943
Improved Methods to Produce Tissue-Engineered Skin Substitutes Suitable for the Permanent Closure of Full-Thickness Skin Injuries, Larouche, D., Cantin-Warren, L., Desgagné, M., Guignard, R., Martel, I., Ayoub, A., Lavoie, A., Gauvin, R., Auger, F.A., Moulin, V.J., Germain, L., BioResearch Open Access, 2016, 10.1089/biores.2016.0036
In Vivo Remodeling of Fibroblast-Derived Vascular Scaffolds Implanted for 6 Months in Rats, Tondreau, M.Y., Laterreur, V., Vallières, K., Gauvin, R., Bourget, J.-M., Tremblay, C., Lacroix, D., Germain, L., Ruel, J., Auger, F.A., BioMed Research International, 2016, 10.1155/2016/3762484
Strategies integrating gene therapy and tissue engineering into the development of treatments for recessive dystrophic epidermolysis bullosa, Piaceski, A.D., Larouche, D., Bisson, F., Ghani, K., Caruso, M., Germain, L., Epidermolysis Bullosa (EB): Prevalence, Clinical Manifestations and Management, 2016
The ROVT Elan Valved Biplex conduits for the reconstruction of the right ventricular outflow tract, Guidoin, R., Fu, Y., Li, B., Weerasena, N., Bourget, J.-M., Paynter, R., Li, X., Lin, J., Wang, L., Qin, B., Guzman, R., Desaulniers, D., Dionne, G., Germain, L., Zhang, Z., Journal of Long-Term Effects of Medical Implants, 2016, 10.1615/JLongTermEffMedImplants.2016013857
The tissue-engineered human cornea as a model to study expression of matrix metalloproteinases during corneal wound healing, Couture, C., Zaniolo, K., Carrier, P., Lake, J., Patenaude, J., Germain, L., Guérin, S.L., Biomaterials, 2016, 10.1016/j.biomaterials.2015.11.006
The triplex BioValsalva prostheses to reconstruct the aortic valve and the aortic root, Fu, Y., Li, B., Bourget, J.M., Bondarenko, O., Lin, J., Guzman, R., Paynter, R., Desaulniers, D., Qin, B., Wang, L., Germain, L., Zhang, Z., Guidoin, R., Journal of Long-Term Effects of Medical Implants, 2016, 10.1615/JLongTermEffMedImplants.2016013541
Transcatheter heart valve crimping and the protecting effects of a polyester cuff,Sertissage des valves cardiaques percutanées et la protection possible d'une collerette de tissu, Guidoin, R., Zegdi, R., Lin, J., Mao, J., Rochette-Drouin, O., How, D., Guan, X., Bruneval, P., Wang, L., Germain, L., Zhang, Z., Morphologie, 2016, 10.1016/j.morpho.2016.06.005
A Floating Thrombus Anchored at the Proximal Anastomosis of a Woven Thoracic Graft Mimicking a Genuine Aortic Dissection, Li, B., Liu, B., Fu, Y., Bondarenko, O., Verdant, A., Rochette-Drouin, O., Lin, J., Bourget, J.-M., Guzman, R., Wang, L., Zhang, Z., Douville, Y., Germain, L., Jing, Z., Guidoin, R., Journal of long-term effects of medical implants, 2015, 10.1615/jlongtermeffmedimplants.2015012263
Contribution of Sp1 to telomerase expression and activity in skin keratinocytes cultured with a feeder layer, Bisson, F., Paquet, C., Bourget, J.-M., Zaniolo, K., Rochette, P.J., Landreville, S., Damour, O., Boudreau, F., Auger, F.A., Guérin, S.L., Germain, L., Journal of Cellular Physiology, 2015, 10.1002/jcp.24706
Effect of 27-MHz radiofrequency on hair follicles: Histological evaluation of skin treated Ex Vivo, Kim, D.H., Lavoie, A., Ratté, G., Beaumont, C., Germain, L., Larouche, D., Dermatologic Surgery, 2015, 10.1097/DSS.0000000000000324
Human adipose-derived stromal cells for the production of completely autologous self-assembled tissue-engineered vascular substitutes, Vallières, K., Laterreur, V., Tondreau, M.Y., Ruel, J., Germain, L., Fradette, J., Auger, F.A., Acta Biomaterialia, 2015, 10.1016/j.actbio.2015.06.011
Mechanical properties of endothelialized fibroblast-derived vascular scaffolds stimulated in a bioreactor, Tondreau, M.Y., Laterreur, V., Gauvin, R., Vallières, K., Bourget, J.-M., Lacroix, D., Tremblay, C., Germain, L., Ruel, J., Auger, F.A., Acta Biomaterialia, 2015, 10.1016/j.actbio.2015.02.026
Potential of newborn and adult stem cells for the production of vascular constructs using the living tissue sheet approach, Bourget, J.-M., Gauvin, R., Duchesneau, D., Remy, M., Auger, F.A., Germain, L., BioMed Research International, 2015, 10.1155/2015/168294
Production of a Bilayered Self-Assembled Skin Substitute Using a Tissue-Engineered Acellular Dermal Matrix, Beaudoin Cloutier, C., Guignard, R., Bernard, G., Gauvin, R., Larouche, D., Lavoie, A., Lacroix, D., Moulin, V.J., Germain, L., Auger, F.A., Tissue Engineering - Part C: Methods, 2015, 10.1089/ten.tec.2015.0258
A new construction technique for tissue-engineered heart valves using the self-Assembly method, Tremblay, C., Ruel, J., Bourget, J.-M., Laterreur, V., Vallières, K., Tondreau, M.Y., Lacroix, D., Germain, L., Auger, F.A., Tissue Engineering - Part C: Methods, 2014, 10.1089/ten.tec.2013.0698
Adherens junction proteins are expressed in collagen corneal equivalents produced in vitro with human cells, Giasson, C.J., Deschambeault, A., Carrier, P., Germain, L., Molecular Vision, 2014
Comparison of the direct burst pressure and the ring tensile test methods for mechanical characterization of tissue-engineered vascular substitutes, Laterreur, V., Ruel, J., Auger, F.A., Vallières, K., Tremblay, C., Lacroix, D., Tondreau, M., Bourget, J.-M., Germain, L., Journal of the Mechanical Behavior of Biomedical Materials, 2014, 10.1016/j.jmbbm.2014.02.017
Progress in developing a living human tissue-engineered tri-leaflet heart valve assembled from tissue produced by the self-assembly approach, Dubé, J., Bourget, J.-M., Gauvin, R., Lafrance, H., Roberge, C.J., Auger, F.A., Germain, L., Acta Biomaterialia, 2014, 10.1016/j.actbio.2014.04.033
Using human umbilical cord cells for tissue engineering: A comparison with skin cells, Hayward, C.J., Fradette, J., Morissette Martin, P., Guignard, R., Germain, L., Auger, F.A., Differentiation, 2014, 10.1016/j.diff.2014.05.001
A comparative study of bovine and porcine pericardium to highlight their potential advantages to manufacture percutaneous cardiovascular implants, Gauvin, R., Marinov, G., Mehri, Y., Klein, J., Li, B., Larouche, D., Guzman, R., Zhang, Z., Germain, L., Guidoin, R., Journal of Biomaterials Applications, 2013, 10.1177/0885328212465482
A tissue-engineered corneal wound healing model for the characterization of reepithelialization, Zaniolo, K., Carrier, P., Guérin, S.L., Auger, F.A., Germain, L., Methods in Molecular Biology, 2013, 10.1007/978-1-62703-505-7_4
Effect of intense pulsed light treatment on human skin in vitro: Analysis of immediate effects on dermal papillae and hair follicle stem cells, Larouche, D., Kim, D.H., Ratté, G., Beaumont, C., Germain, L., British Journal of Dermatology, 2013, 10.1111/bjd.12477
Expression of the α5 integrin gene in corneal epithelial cells cultured on tissue-engineered human extracellular matrices, Lake, J., Zaniolo, K., Gaudreault, M., Carrier, P., Deschambault, A., Bazin, R., Germain, L., Salesse, C., Guérin, S.L., Biomaterials, 2013, 10.1016/j.biomaterials.2013.05.007
Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death, Welsbie, D.S., Yang, Z., Ge, Y., Mitchell, K.L., Zhou, X., Martin, S.E., Berlinicke, C.A., Hackler Jr., L., Fuller, J., Fu, J., Cao, L.-H., Han, B., Auld, D., Xue, T., Hirai, S.-I., Germain, L., Simard-Bisson, C., Blouin, R., Nguyen, J.V., Davis, C.-H.O., Enke, R.A., Boye, S.L., Merbs, S.L., Marsh-Armstrong, N., Hauswirth, W.W., Diantonio, A., Nickells, R.W., Inglese, J., Hanes, J., Yau, K.-W., Quigley, H.A., Zack, D.J., Proceedings of the National Academy of Sciences of the United States of America, 2013, 10.1073/pnas.1211284110
Human epithelial stem cells persist within tissue-engineered skin produced by the self-assembly approach, Lavoie, A., Fugère, C., Beauparlant, A., Goyer, B., Larouche, D., Paquet, C., Desgagné, M., Sauvé, S., Robitaille, H., Dunnwald, M., Kim, D.H., Pouliot, R., Fradette, J., Germain, L., Tissue Engineering - Part A, 2013, 10.1089/ten.tea.2012.0117
Interleukin-10 controls the protective effects of circulating microparticles from patients with septic shock on tissue-engineered vascular media, Mostefai, H.A., Bourget, J.-M., Meziani, F., Martinez, M.C., Leonetti, D., Mercat, A., Asfar, P., Germain, L., Andriantsitohaina, R., Clinical Science, 2013, 10.1042/CS20120441
Irradiated human dermal fibroblasts are as efficient as mouse fibroblasts as a feeder layer to improve human epidermal cell culture lifespan, Bisson, F., Rochefort, É., Lavoie, A., Larouche, D., Zaniolo, K., Simard-Bisson, C., Damour, O., Auger, F.A., Guérin, S.L., Germain, L., International Journal of Molecular Sciences, 2013, 10.3390/ijms14034684
Minimal contraction for tissue-engineered skin substitutes when matured at the air-liquid interface, Gauvin, R., Larouche, D., Marcoux, H., Guignard, R., Auger, F.A., Germain, L., Journal of Tissue Engineering and Regenerative Medicine, 2013, 10.1002/term.543
Prospective study on the treatment of lower-extremity chronic venous and mixed ulcers using tissue-engineered skin substitute made by the self-assembly approach, Boa, O., Cloutier, C.B., Genest, H., Labbé, R., Rodrigue, B., Soucy, J., Roy, M., Arsenault, F., Ospina, C.E., Dubé, N., Rochon, M.-H., Larouche, D., Moulin, V.J., Germain, L., Auger, F.A., Advances in Skin and Wound Care, 2013, 10.1097/01.ASW.0000433102.48268.2a
Qualitatively monitoring binding and expression of the transcription factor sp1 as a useful tool to evaluate the reliability of primary cultured epithelial stem cells in tissue reconstruction, Gaudreault, M., Larouche, D., Germain, L., Guérin, S.L., Methods in Molecular Biology, 2013, 10.1007/978-1-62703-330-5_11
Recent advances in the development of tissue-engineered vascular media made by self-assembly, Bourget, J.-M., Laterreur, V., Guillemette, M., Gauvin, R., Miville-Godin, C., Mounier, M., Ruel, J., Auger, F.A., Veres, T., Germain, L., Procedia Engineering, 2013, 10.1016/j.proeng.2013.05.111
Tendons and Ligament Tissue Engineering, Goulet, F., Auger, F.A., Cloutier, R., Lamontagne, J., Simon, F., Chabaud, S., Germain, L., Hart, D.A., Principles of Tissue Engineering: Fourth Edition, 2013, 10.1016/B978-0-12-398358-9.00059-8
Can marine mammals be a reliable source for the manufacture of prosthetic heart valves for percutaneous surgery?, Guidoin, R., Reed, R.R., Lagaude, A., Bes, T.M., Li, B., Klein, J., Gauvin, R., Guzman, R., Germain, L., Zhang, Z., Journal of Long-Term Effects of Medical Implants, 2012, 10.1615/JLongTermEffMedImplants.v22.i2.20
Cuspal dehiscence at a post and along the stent cloth in a bovine pericardium heart valve implanted for seven years, Guidoin, R., Bes, T.M., Cianciulli, T., Klein, J., Li, B., Gauvin, R., Guzman, R., Rochette-Drouin, O., Germain, L., Zhang, Z., Journal of Long-Term Effects of Medical Implants, 2012, 10.1615/JLongTermEffMedImplants.v22.i2.10
Erratum: Skin substitutes and wound healing (Skin Pharmacol Physiol (2009) 22: 2 (94-102) DOI: 10.1159/000178868), Auger, F.A., Lacroix, D., Germain, L., Skin Pharmacology and Physiology, 2012
Harvesting the potential of the human umbilical cord: Isolation and characterisation of four cell types for tissue engineering applications, Hayward, C.J., Fradette, J., Galbraith, T., Rémy, M., Guignard, R., Gauvin, R., Germain, L., Auger, F.A., Cells Tissues Organs, 2012, 10.1159/000341254
Human fibroblast-derived ECM as a scaffold for vascular tissue engineering, Bourget, J.-M., Gauvin, R., Larouche, D., Lavoie, A., Labbé, R., Auger, F.A., Germain, L., Biomaterials, 2012, 10.1016/j.biomaterials.2012.09.015
Human keratinocytes respond to direct current stimulation by increasing intracellular calcium: Preferential response of poorly differentiated cells, Dubé, J., Rochette-Drouin, O., Lévesque, P., Gauvin, R., Roberge, C.J., Auger, F.A., Goulet, D., Bourdages, M., Plante, M., Moulin, V.J., Germain, L., Journal of Cellular Physiology, 2012, 10.1002/jcp.23008
Rescue of the transcription factors Sp1 and NFI in human skin keratinocytes through a feeder-layer-dependent suppression of the proteasome activity, Duval, C., Gaudreault, M., Vigneault, F., Touzel-Deschênes, L., Rochette, P.J., Masson-Gadais, B., Germain, L., Guérin, S.L., Journal of Molecular Biology, 2012, 10.1016/j.jmb.2012.01.021
A Computer-Controlled Apparatus for the Characterization of Mechanical and Viscoelastic Properties of Tissue-Engineered Vascular Constructs, Levesque, P., Gauvin, R., Larouche, D., Auger, F.A., Germain, L., Cardiovascular Engineering and Technology, 2011, 10.1007/s13239-011-0033-y
Biaxial biomechanical properties of self-assembly tissue-engineered blood vessels, Zaucha, M.T., Gauvin, R., Auger, F.A., Germain, L., Gleason, R.L., Journal of the Royal Society Interface, 2011, 10.1098/rsif.2010.0228
Comparative study of bovine, porcine and avian collagens for the production of a tissue engineered dermis, Parenteau-Bareil, R., Gauvin, R., Cliche, S., Gariépy, C., Germain, L., Berthod, F., Acta Biomaterialia, 2011, 10.1016/j.actbio.2011.06.020
Comparison of the pig and feline models for full thickness corneal transplantation, Brunette, I., Rosolen, S.G., Carrier, M., Abderrahman, M., Nada, O., Germain, L., Proulx, S., Veterinary Ophthalmology, 2011, 10.1111/j.1463-5224.2011.00886.x
Considerations in the choice of a skin donor site for harvesting keratinocytes containing a high proportion of stem cells for culture in vitro, Lavoie, A., Fugère, C., Fradette, J., Larouche, D., Paquet, C., Beauparlant, A., Gauvin, R., Têtu, F.-A., Roy, A., Bouchard, M., Genest, H., Auger, F.A., Germain, L., Burns, 2011, 10.1016/j.burns.2010.09.004
Corneal endothelial toxicity of air and SF6, Landry, H., Aminian, A., Hoffart, L., Nada, O., Bensaoula, T., Proulx, S., Carrier, P., Germain, L., Brunette, I., Investigative Ophthalmology and Visual Science, 2011, 10.1167/iovs.10-6187
Dynamic mechanical stimulations induce anisotropy and improve the tensile properties of engineered tissues produced without exogenous scaffolding, Gauvin, R., Parenteau-Bareil, R., Larouche, D., Marcoux, H., Bisson, F., Bonnet, A., Auger, F.A., Bolduc, S., Germain, L., Acta Biomaterialia, 2011, 10.1016/j.actbio.2011.05.034
Hair follicles guide nerve migration in vitro and in vivo in tissue-engineered skin, Gagnon, V., Larouche, D., Parenteau-Bareil, R., Gingras, M., Germain, L., Berthod, F., Journal of Investigative Dermatology, 2011, 10.1038/jid.2011.34
Mechanical properties of tissue-engineered vascular constructs produced using arterial or venous cells, Gauvin, R., Guillemette, M., Galbraith, T., Bourget, J.-M., Larouche, D., Marcoux, H., Aubé, D., Hayward, C., Auger, F.A., Germain, L., Tissue Engineering - Part A, 2011, 10.1089/ten.tea.2010.0613
Stem cells of the skin and cornea: Their clinical applications in regenerative medicine, Proulx, S., Fradette, J., Gauvin, R., Larouche, D., Germain, L., Current Opinion in Organ Transplantation, 2011, 10.1097/MOT.0b013e32834254f1
Tissue-engineered skin preserving the potential of epithelial cells to differentiate into hair after grafting, Larouche, D., Cuffley, K., Paquet, C., Germain, L., Tissue Engineering - Part A, 2011, 10.1089/ten.tea.2010.0403
A novel single-step self-assembly approach for the fabrication of tissue-engineered vascular constructs, Gauvin, R., Ahsan, T., Larouche, D., Lévesque, P., Dubé, J., Auger, F.A., Nerem, R.M., Germain, L., Tissue Engineering - Part A, 2010, 10.1089/ten.tea.2009.0313
Identification of epithelial stem cells in vivo and in vitro using keratin 19 and BrdU., Larouche, D., Lavoie, A., Paquet, C., Simard-Bisson, C., Germain, L., Methods in molecular biology (Clifton, N.J.), 2010, 10.1007/978-1-60761-380-0_27
Normal human epithelial cells regulate the size and morphology of tissue-engineered capillaries, Rochon, M.-H., Fradette, J., Fortin, V., Tomasetig, F., Roberge, C.J., Baker, K., Berthod, F., Auger, F.A., Germain, L., Tissue Engineering - Part A, 2010, 10.1089/ten.tea.2009.0090
Reconstruction of a human cornea by the self-assembly approach of tissue engineering using the three native cell types, Proulx, S., Uwamaliya, J.D., Carrier, P., Deschambeault, A., Audet, C., Giasson, C.J., Guérin, S.L., Auger, F.A., Germain, L., Molecular Vision, 2010
Restoration of the transepithelial potential within tissue-engineered human skin in vitro and during the wound healing process in vivo, Dubé, J., Rochette-Drouin, O., Lévesque, P., Gauvin, R., Roberge, C.J., Auger, F.A., Goulet, D., Bourdages, M., Plante, M., Germain, L., Moulin, V.J., Tissue Engineering - Part A, 2010, 10.1089/ten.tea.2010.0030
The small heat-shock protein Hsp27 undergoes ERK-dependent phosphorylation and redistribution to the cytoskeleton in response to dual leucine zipper-bearing kinase expression, Robitaille, H., Simard-Bisson, C., Larouche, D., Tanguay, R.M., Blouin, R., Germain, L., Journal of Investigative Dermatology, 2010, 10.1038/jid.2009.185
Tissue engineering of skin and cornea: Development of new models for in vitro studies, Paquet, C., Larouche, D., Bisson, F., Proulx, S., Simard-Bisson, C., Gaudreault, M., Robitaille, H., Carrier, P., Martel, I., Duranceau, L., Auger, F.A., Fradette, J., Guérin, S.L., Germain, L., Annals of the New York Academy of Sciences, 2010, 10.1111/j.1749-6632.2009.05373.x
Tissue-engineered vascular adventitia with vasa vasorum improves graft integration and vascularization through inosculation, Guillemette, M.D., Gauvin, R., Perron, C., Labbé, R., Germain, L., Auger, F.A., Tissue Engineering - Part A, 2010, 10.1089/ten.tea.2009.0612
Tissue-engineered vascular substitutes: New models toward successful small diameter grafts, D'Orléans-Juste, P., Lacroix, D., Germain, L., Auger, F.A., Advances in Vascular Medicine, 2010, 10.1007/978-1-84882-637-3_9
A novel cylindrical biaxial computer-controlled bioreactor and biomechanical testing device for vascular tissue engineering, Zaucha, M.T., Raykin, J., Wan, W., Gauvin, R., Auger, F.A., Germain, L., Michaels, T.E., Gleason Jr., R.L., Tissue Engineering - Part A, 2009, 10.1089/ten.tea.2008.0369
Applications of human tissue-engineered blood vessel models to study the effects of shed membrane microparticles from T-lymphocytes on vascular function, Pricci, M., Bourget, J.-M., Robitaille, H., Porro, C., Soleti, R., Mostefai, H.A., Auger, F.A., Martinez, M.C., Andriantsitohaina, R., Germain, L., Tissue Engineering - Part A, 2009, 10.1089/ten.tea.2007.0360
Differential binding of the transcription factors Sp1, AP-1, and NFI to the promoter of the human α5 integrin gene dictates its transcriptional activity, Gingras, M.-È., Masson-Gadais, B., Zaniolo, K., Leclerc, S., Drouin, R., Germain, L., Guérin, S.L., Investigative Ophthalmology and Visual Science, 2009, 10.1167/iovs.08-2059
Evolution of three dimensional skin equivalent models reconstructed in vitro by tissue engineering, Auxenfans, C., Fradette, J., Lequeux, C., Germain, L., Kinikoglu, B., Bechetoille, N., Braye, F., Auger, F.A., Damour, O., European Journal of Dermatology, 2009, 10.1684/ejd.2008.0573
Identification of functional markers in a self-assembled skin substitute in vitro, Cvetkovska, B., Islam, N., Goulet, F., Germain, L., In Vitro Cellular and Developmental Biology - Animal, 2009, 10.1007/s11626-008-9140-y
Impact of cell source on human cornea reconstructed by tissue engineering, Carrier, P., Deschambeault, A., Audet, C., Talbot, M., Gauvin, R., Giasson, C.J., Auger, F.A., Guérin, S.L., Germain, L., Investigative Ophthalmology and Visual Science, 2009, 10.1167/iovs.08-2001
Regeneration of skin and cornea by tissue engineering, Larouche, D., Paquet, C., Fradette, J., Carrier, P., Auger, F.A., Germain, L., Methods in Molecular Biology, 2009, 10.1007/978-1-59745-060-7_15
Regenerative medicine: Stem cells, cellular and matricial interactions in the reconstruction of skin and cornea by tissue engineering,La médecine régénératrice : les cellules souches, les interactions cellulaires et matricielles dans la reconstruction cutanée et cornéenne par génie tissulaire, Larouche, D., Lavoie, A., Proulx, S., Paquet, C., Carrier, P., Beauparlant, A., Auger, F.A., Germain, L., Pathologie Biologie, 2009, 10.1016/j.patbio.2008.04.015
Regulation of skin collagen metabolism in vitro using a pulsed 660 nm led light source: Clinical correlation with a single-blinded study, Barolet, D., Roberge, C.J., Auger, F.A., Boucher, A., Germain, L., Journal of Investigative Dermatology, 2009, 10.1038/jid.2009.186
Skin substitutes and wound healing, Auger, F.A., Lacroix, D., Germain, L., Skin Pharmacology and Physiology, 2009, 10.1159/000178868
Stem cells and their implications in pathophysiology, humane treatment, and dermatology,Les cellules souches et leurs implications en physiopathologie, en thérapeutique humaine et en dermatologie, Germain, L., Annales de Dermatologie et de Venereologie, 2009, 10.1016/j.annder.2009.10.193
Surface topography induces 3D self-orientation of cells and extracellular matrix resulting in improved tissue function, Guillemette, M.D., Cui, B., Roy, E., Gauvin, R., Giasson, C.J., Esch, M.B., Carrier, P., Deschambeault, A., Dumoulin, M., Toner, M., Germain, L., Veres, T., Auger, F.A., Integrative Biology, 2009, 10.1039/b820208g
Tissue engineering of feline corneal endothelium using a devitalized human cornea as carrier, Proulx, S., Audet, C., D'Arc Uwamaliya, J., Deschambeault, A., Carrier, P., Giasson, C.J., Brunette, I., Germain, L., Tissue Engineering - Part A, 2009, 10.1089/ten.tea.2008.0208
Tissue engineering of human cornea, Proulx, S., Guillemette, M., Carrier, P., Auger, F.A., Germain, L., Giasson, C.J., Gaudreault, M., Guérin, S.L., Biomaterials and Regenerative Medicine in Ophthalmology, 2009, 10.1533/9781845697433.1.150
Transplantation of a tissue-engineered corneal endothelium reconstructed on a devitalized carrier in the feline model, Proulx, S., Bensaoula, T., Nada, O., Audet, C., Uwamaliya, J.D., Devaux, A., Brunette, I., Germain, L., Brunette, I., Investigative Ophthalmology and Visual Science, 2009, 10.1167/iovs.08-2793
Characterization of wound reepithelialization using a new human tissue-engineered corneal wound healing model, Carrier, P., Deschambeault, A., Talbot, M., Giasson, C.J., Auger, F.A., Guérin, S.L., Germain, L., Investigative Ophthalmology and Visual Science, 2008, 10.1167/iovs.07-0904
IFATS collection: Using human adipose-derived stem/stromal cells for the production of new skin substitutes, Trottier, V., Marceau-Fortier, G., Germain, L., Vincent, C., Fradette, J., Stem Cells, 2008, 10.1634/stemcells.2008-0031
Transcriptional regulation of the human α6 integrin gene by the transcription factor NFI during corneal wound healing, Gaudreault, M., Vigneault, F., Gingras, M.-E., Leclerc, S., Carrier, P., Germain, L., Guérin, S.L., Investigative Ophthalmology and Visual Science, 2008, 10.1167/iovs.08-1913
Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile, Larouche, D., Tong, X., Fradette, J., Coulombe, P.A., Germain, L., FASEB Journal, 2008, 10.1096/fj.07-8109com
Adventitia contribution to vascular contraction: Hints provided by tissue-engineered substitutes, Auger, F.A., D'Orléans-Juste, P., Germain, L., Cardiovascular Research, 2007, 10.1016/j.cardiores.2007.06.001
Optimization of culture conditions for porcine corneal endothelial cells, Proulx, S., Bourget, J.-M., Gagnon, N., Martel, S., Deschambeault, A., Carrier, P., Giasson, C.J., Auger, F.A., Brunette, I., Germain, L., Molecular Vision, 2007
Polyphenols modulate calcium-independent mechanisms in human arterial tissue-engineered vascular media, Diebolt, M., Laflamme, K., Labbé, R., Auger, F.A., Germain, L., Andriantsitohaina, R., Journal of Vascular Surgery, 2007, 10.1016/j.jvs.2007.05.031
Tendons and ligaments, Goulet, F., Germain, L., Poole, A.R., Auger, F.A., Principles of Tissue Engineering, 2007, 10.1016/B978-012370615-7/50064-0
The antiwrinkle effect of topical concentrated 2-dimethylaminoethanol involves a vacuolar cytopathology, Morissette, G., Germain, L., Marceau, F., British Journal of Dermatology, 2007, 10.1111/j.1365-2133.2007.07681.x
Adventitia contribution in vascular tone: Insights from adventitia-derived cells in a tissue-engineered human blood vessel, Laflamme, K., Roberge, C.J., Grenier, G., Rémy-Zolghadri, M., Pouliot, S., Baker, K., Labbé, R., D'Orléans-Juste, P., Auger, F.A., Germain, L., FASEB Journal, 2006, 10.1096/fj.05-4702fje
Amnion and ocular surface problems,Amnios et problèmes de surface oculaire, Giasson, C.J., Bouchard, C., Boisjoly, H., Germain, L., Medecine/Sciences, 2006, 10.1051/medsci/20062267639
Autologous transplantation of rabbit limbal epithelia cultured on fibrin gels for ocular surface reconstruction, Talbot, M., Carrier, P., Giasson, C.J., Deschambeault, A., Guérin, S.L., Auger, F.A., Bazin, R., Germain, L., Molecular Vision, 2006
Canadian haematopoietic stem cell scientists received the Lasker Award,Des Canadiens «précurseurs de la recherche sur les cellules souches hématopoïétiques» lauréats du prix Lasker, Germain, L., Larouche, D., Paquet, C., Medecine/Sciences, 2006, 10.1051/medsci/2006222212
Extracellular matrix deposition by fibroblasts is necessary to promote capillary-like tube formation in vitro, Berthod, F., Germain, L., Tremblay, N., Auger, F.A., Journal of Cellular Physiology, 2006, 10.1002/jcp.20584
Mechanical loading modulates the differentiation state of vascular smooth muscle cells, Grenier, G., Rémy-Zolghadri, M., Bergeron, F., Guignard, R., Baker, K., Labbé, R., Auger, F.A., Germain, L., Tissue Engineering, 2006, 10.1089/ten.2006.12.3159
Severe oily ichthyosis in monozygotic twins mimicking Chanarin-Dorfman syndrome but not associated with a mutation of the CGI58 gene [10], Solomon, C., Bernier, L., Germain, L., Dufour, R., Davignon, J., Archives of Dermatology, 2006, 10.1001/archderm.142.3.402
The feeder layer-mediated extended lifetime of cultured human skin keratinocytes is associated with altered levels of the transcription factors Sp1 and Sp3, Masson-Gadais, B., Fugère, C., Paquet, C., Leclerc, S., Lefort, N.R., Germain, L., Guérin, S.L., Journal of Cellular Physiology, 2006, 10.1002/jcp.20529
Tissue-engineered human vascular media produced in vitro by the self-assembly approach present functional properties similar to those of their native blood vessels, Laflamme, K., Roberge, C.J., Pouliot, S., D'Orléans-Juste, P., Auger, F.A., Germain, L., Tissue Engineering, 2006, 10.1089/ten.2006.12.2275
In vitro evaluation of the angiostatic potential of drugs using an endothelialized tissue-engineered connective tissue, Tremblay, P.-L., Berthod, F., Germain, L., Auger, F.A., Journal of Pharmacology and Experimental Therapeutics, 2005, 10.1124/jpet.105.089524
Inosculation of tissue-engineered capillaries with the host's vasculature in a reconstructed skin transplanted on mice, Tremblay, P.-L., Hudon, V., Berthod, F., Germain, L., Auger, F.A., American Journal of Transplantation, 2005, 10.1111/j.1600-6143.2005.00790.x
Keratin 19 as a stem cell marker in vivo and in vitro., Larouche, D., Hayward, C., Cuffley, K., Germain, L., Methods in molecular biology (Clifton, N.J.), 2005
Mechanism of potentiation by polyphenols of contraction in human vein-engineered media, Diebolt, M., Germain, L., Auger, F.A., Andriantsitohaina, R., American Journal of Physiology - Heart and Circulatory Physiology, 2005, 10.1152/ajpheart.01194.2004
MMP-2 expression in uveal melanoma: Differential activation status dictated by the cellular environment, Bérubé, M., Deschambeault, A., Boucher, M., Germain, L., Petitclerc, E., Guérin, S.L., Molecular Vision, 2005
Role of the extracellular matrix proteins in the resistance of SP6.5 uveal melanoma cells toward cisplatin., Bérubé, M., Talbot, M., Collin, C., Paquet-Bouchard, C., Germain, L., Guérin, S.L., Petitclerc, E., International journal of oncology, 2005, 10.3892/ijo.26.2.405
The mitogen-activated protein kinase kinase kinase dual leucine zipper-bearing kinase (DLK) acts as a key regulator of keratinocyte terminal differentiation, Robitaille, H., Proulx, R., Robitaille, K., Blouin, R., Germain, L., Journal of Biological Chemistry, 2005, 10.1074/jbc.M411619200
Tissue reorganization in response to mechanical load increases functionality, Grenier, G., Rémy-Zolghadri, M., Larouche, D., Gauvin, R., Baker, K., Bergeron, F., Dupuis, D., Langelier, E., Rancourt, D., Auger, F.A., Germain, L., Tissue Engineering, 2005, 10.1089/ten.2005.11.90
Tissue-engineered human vascular media with a functional endothelin system, Laflamme, K., Roberge, C.J., Labonté, J., Pouliot, S., D'Orléans-Juste, P., Auger, F.A., Germain, L., Circulation, 2005, 10.1161/01.CIR.0000153850.53419.50
Endothelium properties of a tissue-engineered blood vessel for small-diameter vascular reconstruction, Rémy-Zolghadri, M., Laganière, J., Oligny, J.-F., Germain, L., Auger, F.A., Journal of Vascular Surgery, 2004, 10.1016/j.jvs.2003.08.007
Human tissue engineered blood vessels: A novel support for vascular biology and pharmacology research,Vaisseaux humains reconstitués par génie tissulaire, Stoclet, J.-C., Laflamme, K., Auger, F.A., Germain, L., Medecine/Sciences, 2004, 10.1051/medsci/2004206-7675
Investigation of ultrashort pulse laser ablation of the cornea and hydrogels for eye microsurgery, Girard, G., Zhou, S., Bigaouette, N., Brunette, I., Chaker, M., Germain, L., Lavertu, P.-L., Martin, F., Olivié, G., Ozaki, T., Parent, M., Vidal, F., Kieffer, J.-C., Proceedings of SPIE - The International Society for Optical Engineering, 2004, 10.1117/12.567111
Peptides from milk protein hydrolysates to improve the growth of human keratinocytes in culture, Amiot, J., Germain, L., Turgeon, S., Lemay, M., Ory-Salam, C., Auger, F.A., International Dairy Journal, 2004, 10.1016/j.idairyj.2003.11.007
Recent optimization of a tissue engineered blood vessel: The LOEX experience, Auger, F.A., Laflamme, K., Grenier, G., Rémy-Zolghadri, M., Germain, L., International Congress Series, 2004, 10.1016/S0531-5131(03)01768-0
Shear stress induced MAPKinases activation in endothelial cells cultured on vascular prostheses, Rémy-Zolghadri, M., Fernandez, Ph., Daculsi, R., Oligny, J.F., Bareille, R., Bordenave, L., Auger, F.A., Germain, L., Archives of Physiology and Biochemistry, 2004
The graft of a human endothelializated reconstructed skin accelerates the time of revascularization, Tremblay, P.-L., Hudon, V., Berthod, F., Germain, L., Auger, F.A., Transactions - 7th World Biomaterials Congress, 2004
Tissue-engineered skin substitutes: From in vitro constructs to in vivo applications, Auger, F.A., Berthod, F., Moulin, V., Pouliot, R., Germain, L., Biotechnology and Applied Biochemistry, 2004, 10.1042/ba20030229
A tissue-engineered endothelialized dermis to study the modulation of angiogenic and angiostatic molecules on capillary-like tube formation in vitro, Hudon, V., Berthod, F., Black, A.F., Damour, O., Germain, L., Auger, F.A., British Journal of Dermatology, 2003, 10.1046/j.1365-2133.2003.05298.x
Influence of Sp1/Sp3 expression on corneal epithelial cells proliferation and differentiation properties in reconstructed tissues, Gaudreault, M., Carrier, P., Larouche, K., Leclerc, S., Giasson, M., Germain, L., Guérin, S.L., Investigative Ophthalmology and Visual Science, 2003, 10.1167/iovs.02-0707
Isolation and culture of the three vascular cell types from a small vein biopsy sample, Grenier, G., Rémy-Zolghadri, M., Guignard, R., Bergeron, F., Labbé, R., Auger, F.A., Germain, L., In Vitro Cellular and Developmental Biology - Animal, 2003, 10.1007/s11626-003-0007-y
Normal human Merkel cells are present in epidermal cell populations isolated and cultured from glabrous and hairy skin sites, Fradette, J., Larouche, D., Fugère, C., Guignard, R., Beauparlant, A., Couture, V., Caouette-Laberge, L., Roy, A., Germain, L., Journal of Investigative Dermatology, 2003, 10.1046/j.1523-1747.2003.12024.x
Production of tissue-engineered three-dimensional human bronchial models, Paquette, J.S., Tremblay, P., Bernier, V., Auger, F.A., Laviolette, M., Germain, L., Boutet, M., Boulet, L.P., Goulet, F., In Vitro Cellular and Developmental Biology - Animal, 2003, 10.1290/1543-706x(2003)039<0213:potthb>2.0.co;2
Tissue engineering: A tool to understand the physiological mechanisms,Le génie tissulaire au service de la compréhension du vivant, Moulin, V., Goulet, F., Berthod, F., Germain, L., Auger, F.A., Medecine/Sciences, 2003, 10.1051/medsci/200319101003
A truly new approach for tissue engineering: the LOEX self-assembly technique., Auger, F.A., Rémy-Zolghadri, M., Grenier, G., Germain, L., Ernst Schering Research Foundation workshop, 2002, 10.1007/978-3-662-04816-0_6
Applications of the tissue-engineered human blood vessel reconstructed by the self-assembly approach, Lucie, G., François, A., Murielle, R.-Z., Karina, L., Guillaume, G., Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products, 2002
Engineering human tissues for in vivo applications, Germain, L., Goulet, F., Moulin, V., Berthod, F., Auger, F.A., Annals of the New York Academy of Sciences, 2002, 10.1111/j.1749-6632.2002.tb03099.x
Engineering human tissues for in vivo applications: Storage and translational issues for tissue repair and regeneration, Germain, L., Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, 2002
Reconstructed human skin produced in vitro and grafted on athymic mice, Pouliot, R., Larouche, D., Auger, F.A., Juhasz, J., Xu, W., Li, H., Germain, L., Transplantation, 2002, 10.1097/00007890-200206150-00010
Storage and translational issues in reparative medicine: Breakout session summary, Kocsis, J.D., Toner, M., Anderson, D.K., Brockbank, K., Germain, L., Lee, R.C., Ratner, B.D., Kocsis, J.D., Annals of the New York Academy of Sciences, 2002, 10.1111/j.1749-6632.2002.tb03101.x
A human tissue-engineered vascular media: A new model for pharmacological studies of contractile responses, L'Heureux, N., Stoclet, J.-C., Auger, F.A., Lagaud, G.J.-L., Germain, L., Andriantsitohaina, R., FASEB Journal, 2001, 10.1096/fj.00-0283com
Characterization of a 150 kDa accessory receptor for TGF-β1 on keratinocytes: Direct evidence for a GPI anchor and ligand binding of the released form, Tam, B.Y.Y., Larouche, D., Germain, L., Hooper, N.M., Philip, A., Journal of Cellular Biochemistry, 2001, 10.1002/jcb.1074
Collagen fibril network and elastic system remodeling in a reconstructed skin transplanted on nude mice, Berthod, F., Germain, L., Li, H., Xu, W., Damour, O., Auger, F.A., Matrix Biology, 2001, 10.1016/S0945-053X(01)00162-7
Fetal and adult human skin fibroblasts display intrinsic differences in contractile capacity, Moulin, V., Tam, B.Y.Y., Castilloux, G., Auger, F.A., O'Connor-McCourt, M.D., Philip, A., Germain, L., Journal of Cellular Physiology, 2001, 10.1002/jcp.1110
Mechanisms of wound reepithelialization: Hints from a tissue-engineered reconstructed skin to long-standing questions, Laplante, A.F., Germain, L., Auger, F.A., Moulin, V., FASEB Journal, 2001, 10.1096/fj.01-0250com
Morphological changes of human skin cells exposed to a DC electric field In vitro using a new exposure system, Méthot, S., Moulin, V., Rancourt, D., Bourdages, M., Goulet, D., Plante, M., Auger, F.A., Germain, L., Canadian Journal of Chemical Engineering, 2001, 10.1002/cjce.5450790428
Production of bioengineered cancer tissue constructs in vitro: Epithelium-mesenchyme heterotypic interactions, Wang, C.S., Goulet, F., Auger, F., Tremblay, N., Germain, L., Têtu, B., In Vitro Cellular and Developmental Biology - Animal, 2001, 10.1290/1071-2690(2001)037<0434:POBCTC>2.0.CO;2
Selective culture of epithelial cells from primary breast carcinomas using irradiated 3T3 cells as feeder layer, Wang, C.S., Goulet, F., Tremblay, N., Germain, L., Auger, F., Têtu, B., Pathology Research and Practice, 2001, 10.1078/0344-0338-00030
Simultaneous isolation of keratinocytes and fibroblasts from a human cutaneous biopsy for the production of autologous reconstructed skin, Rochon, M.-H., Gauthier, M.-J., Auger, F.A., Germain, L., Canadian Journal of Chemical Engineering, 2001, 10.1002/cjce.5450790427
Can we produce a human corneal equivalent by tissue engineering?, Germain, L., Carrier, P., Auger, F.A., Salesse, C., Guérin, S.L., Progress in Retinal and Eye Research, 2000, 10.1016/S1350-9462(00)00005-7
Development of an in vitro angiogenesis model within an endothelialized reconstructed dermis to study angiogenic and angiostatic molecules, Hudon, V., Berthod, F., Black, A.F., Germain, L., Damour, O., Auger, F.A., Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling, 2000
Erratum: Antiangiogenic effects of the oral administration of liquid cartilage extract in humans (Journal of Surgical Research (1999) 87:1 (108- 113)), Berbari, P., Thibodeau, A., Germain, L., Saint-Cyr, M., Gaudreau, P., Elkhouri, S., Dupont, E., Garrel, D.R., Journal of Surgical Research, 2000, 10.1006/jsre.2000.5849
Establishment and characterization of a new cell line derived from a human primary breast carcinoma, Wang, C.S., Goulet, F., Lavoie, J., Drouin, R.E., Auger, F., Champetier, S., Germain, L., Têtu, B., Cancer Genetics and Cytogenetics, 2000, 10.1016/S0165-4608(99)00253-8
Improvement of the vascularization of a human endothelialized reconstructed skin graft on athymic mice, Hudon, V., Berthod, F., Black, A.F., Germain, L., Auger, F.A., Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling, 2000
Multistep production of bioengineered skin substitutes: Sequential modulation of culture conditions, Auger, F.A., Pouliot, R., Tremblay, N., Guignard, R., Noël, P., Juhasz, J., Germain, L., Goulet, F., In Vitro Cellular and Developmental Biology - Animal, 2000, 10.1290/1071-2690(2000)036<0096:MPOBSS>2.3.CO;2
Optimization of a cutaneous wound-healing model for the screening of pharmaceutical compounds, Laplante, A.F., Germain, L., Auger, F.A., Moulin, V., Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling, 2000
Role of wound healing myofibroblasts on re-epithelialization of human skin, Moulin, V., Auger, F.A., Garrel, D., Germain, L., Burns, 2000, 10.1016/S0305-4179(99)00091-1
The mixed lineage kinase leucine-zipper protein kinase exhibits a differentiation-associated localization in normal human skin and induces keratinocyte differentiation upon overexpression, Germain, L., Fradette, J., Robitaille, H., Guignard, R., Grondin, G., Nadeau, A., Blouin, R., Journal of Investigative Dermatology, 2000, 10.1046/j.1523-1747.2000.00024.x
Tissue Engineering and Biomaterials Symposium of the Xle Entretiens du Centre Jacques Cartier, Lyon, December 1998: Editorial, Germain, L., Medical and Biological Engineering and Computing, 2000, 10.1007/bf02344777
Tissue engineering of the vascular system: From capillaries to larger blood vessels, Germain, L., Rémy-Zolghadri, M., Auger, F., Medical and Biological Engineering and Computing, 2000, 10.1007/BF02344782
Tissue engineering of the vascular system: full spectrum of tissue engineered blood vessels (TEBV), Auger, Francois, Remy-Zolghadri, Murielle, Black, Annie, Grenier, Guillaume, Germain, Lucie, Annals of Biomedical Engineering, 2000
A novel approach for studying angiogenesis: A human skin equivalent with a capillary-like network, Black, A.F., Hudon, V., Damour, O., Germain, L., Auger, F.A., Cell Biology and Toxicology, 1999, 10.1023/A:1007541713398
Antiangiogenic effects of the oral administration of liquid cartilage extract in humans, Berbari, P., Thibodeau, A., Germain, L., Saint-Cyr, M., Gaudreau, P., El-Khouri, S., Dupont, E., Garrel, D.R., Journal of Surgical Research, 1999, 10.1006/jsre.1999.5698
Characterization of a new tissue-engineered human skin equivalent with hair, Michel, M., L'Heureux, N., Pouliot, R., Xu, W., Auger, F.A., Germain, L., In Vitro Cellular and Developmental Biology - Animal, 1999, 10.1007/s11626-999-0081-x
Cyclic traction machine for long-term culture of fibroblast-populated collagen gels, Langelier, E., Rancourt, D., Bouchard, S., Lord, C., Stevens, P.-P., Germain, L., Auger, F.A., Annals of Biomedical Engineering, 1999, 10.1114/1.166
Physical characterization of the stratum corneum of an in vitro human skin equivalent produced by tissue engineering and its comparison with normal human skin by ATR-FTIR spectroscopy and thermal analysis (DSC), Pouliot, R., Germain, L., Auger, F.A., Tremblay, N., Juhasz, J., Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, 1999, 10.1016/S1388-1981(99)00086-4
Reconstructed human cornea produced in vitro by tissue engineering, Germain, L., Auger, F.A., Grandbois, E., Guignard, R., Giasson, M., Boisjoly, H., Guérin, S.L., Pathobiology, 1999, 10.1159/000028064
What is new in mechanical properties of tissue-engineered organs., Auger, F.A., Berthod, F., Goulet, F., Germain, L., Current topics in pathology. Ergebnisse der Pathologie, 1999, 10.1007/978-3-642-58456-5_9
What's new in human wound-healing myofibroblasts?, Moulin, V., Garrel, D., Auger, F.A., O'Connor-McCourt, M., Castilloux, G., Germain, L., Current topics in pathology. Ergebnisse der Pathologie, 1999, 10.1007/978-3-642-58456-5_13
A completely biological tissue-engineered human blood vessel, L'Heureux, N., Pâquet, S., Labbé, R., Germain, L., Auger, F.A., FASEB Journal, 1998, 10.1096/fasebj.12.1.47
Expression of heat shock proteins in mouse skin during wound healing, Laplante, A.F., Moulin, V., Auger, F.A., Landry, J., Li, H., Morrow, G., Tanguay, R.M., Germain, L., Journal of Histochemistry and Cytochemistry, 1998, 10.1177/002215549804601109
In vitro reconstruction of a human capillary-like network in a tissue- engineered skin equivalent, Black, A.F., Berthod, F., L'Heureux, N., Germain, L., Auger, F.A., FASEB Journal, 1998, 10.1096/fasebj.12.13.1331
Influence of endothelial cells on structure, biochemistry and functionality of epidermis reconstructed on synthetic porous membrane, Pouliot, R., Robert, M., Germain, L., Noël-Hudson, M.-S., Lindenbaum, A., Juhasz, J., Auger, F.A., Wepierre, J., Skin Pharmacology and Applied Skin Physiology, 1998, 10.1159/000029828
Mechanical properties of human skin equivalents submitted to cyclic tensile forces, Lafrance, H., Yahia, L., Germain, L., Auger, F.A., Skin Research and Technology, 1998, 10.1111/j.1600-0846.1998.tb00115.x
Modulated response to cytokines of human wound healing myofibroblasts compared to dermal fibroblasts, Moulin, V., Castilloux, G., Auger, F.A., Garrel, D., O'Connor-McCourt, M.D., Germain, L., Experimental Cell Research, 1998, 10.1006/excr.1997.3827
TGF-β receptor expression on human keratinocytes: A 150 kDa GPI- anchored TGF-β1 binding protein forms a heteromeric complex with type I and type II receptors, Tam, B.Y.Y., Germain, L., Philip, A., Journal of Cellular Biochemistry, 1998, 10.1002/(SICI)1097-4644(19980915)70:4<573::AID-JCB13>3.0.CO;2-I
The type I keratin 19 possesses distinct and context-dependent assembly properties, Fradette, J., Germain, L., Seshaiah, P., Coulombe, P.A., Journal of Biological Chemistry, 1998, 10.1074/jbc.273.52.35176
Tissue-engineered human skin substitutes developed from collagen-populated hydrated gels: Clinical and fundamental applications, Auger, F.A., Rouabhia, M., Goulet, F., Berthod, F., Moulin, V., Germain, L., Medical and Biological Engineering and Computing, 1998, 10.1007/BF02518887
Differential expression of collagens XII and XIV in human skin and in reconstructed skin, Berthod, F., Germain, L., Guignard, R., Lethias, C., Garrone, R., Damour, O., Van Der Rest, M., Auger, F.A., Journal of Investigative Dermatology, 1997, 10.1111/1523-1747.ep12292122
Fetal and postnatal sera differentially modulate human dermal fibroblast phenotypic and functional features in vitro, Moulin, V., Auger, F.A., O'Connor-McCourt, M., Germain, L., Journal of Cellular Physiology, 1997, 10.1002/(SICI)1097-4652(199704)171:1<1::AID-JCP1>3.0.CO;2-S
From newborn to adult: Phenotypic and functional properties of skin equivalent and human skin as a function of donor age, Michel, M., L'Heureux, N., Auger, F.A., Germain, L., Journal of Cellular Physiology, 1997, 10.1002/(SICI)1097-4652(199705)171:2<179::AID-JCP8>3.0.CO;2-L
Use of in vitro reconstructed skin to cover skin flap donor site, Li, H., Berthod, F., Xu, W., Damour, O., Germain, L., Auger, F.A., Journal of Surgical Research, 1997, 10.1006/jsre.1997.5229
Grafting on nude mice of living skin equivalents produced using human collagens, López Valle, C.A., Germain, L., Rouabhia, M., Xu, W., Guignard, R., Goulet, F., Auger, F.A., Transplantation, 1996, 10.1097/00007890-199608150-00003
Keratin 19 as a biochemical marker of skin stem cells in vivo and in vitro: Keratin 19 expressing cells are differentially localized in function of anatomic sites, and their number varies with donor age and culture stage, Michel, M., Török, N., Godbout, M.-J., Lussier, M., Gaudreau, P., Royal, A., Germain, L., Journal of Cell Science, 1996
Morphologic and Functional Properties of Bronchial Cells Isolated from Normal and Asthmatic Subjects, Goulet, F., Boulet, L.-P., Chakir, J., Tremblay, N., Dubé, J., Laviolette, M., Beutet, M., Xu, W., Germain, L., Auger, F.A., American Journal of Respiratory Cell and Molecular Biology, 1996, 10.1165/ajrcmb.15.3.8810634
Use of human vessels and human vascular smooth muscle cells in pharmacology, Stoclet, J.-C., Andriantsitohaina, R., L'heureux, N., Martinez, C., Germain, L., Auger, F., Cell Biology and Toxicology, 1996, 10.1007/BF00438149
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Depuis 2009
Anabelle Demers - Maitrîse avec mémoire - En cours
Andréanne Cartier - Maitrîse avec mémoire - En cours
Bettina Cattier - Doctorat - En cours
Etienne Savard - Maitrîse avec mémoire - En cours
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Francis Bisson - Maitrîse avec mémoire - 2012/05
Jean-Michel Bourget - Doctorat - 2014/05
Carolyne Simard-Bisson - Doctorat - 2015/09
Chanel Beaudoin-Cloutier - Doctorat - 2016/05
Camille Couture - Maitrîse avec mémoire - 2016/05
Angela Dakiw Piaceski - Maitrîse avec mémoire - 2016/09
Michael Boivin-Welch - Maitrîse avec mémoire - 2019/01
Gaëtan Le Bel - Doctorat - 2020/05
Alex Larose - Maitrîse avec mémoire - 2021/05
Sergio Cortez Ghio - Doctorat - 2021/09
Encadrement d'étudiant(e)s pour les programmes suivants :
*Les supervisions d’étudiant(e)s de 1er cycle en
stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées
ultérieurement.
Vice-décanat à la recherche et aux études supérieures Pavillon Ferdinand-Vandry Université Laval 1050, avenue de la Médecine, local 4645 Québec (Québec) G1V 0A6 Canada
Catherine Comtois Agente de gestion des études etudes.sup2@fmed.ulaval.ca Biostatistique Épidémiologie Évaluation économique des technologies de la santé Santé publique
Marianne Rivest et Claudia Gonzalez Agentes de gestion des études etudes.sup1@fmed.ulaval.ca Biologie cellulaire et moléculaire Génomique fonctionnelle Médecine moléculaire Microbiologie-immunologie Neurosciences
Isabelle Tremblay Agente de gestion des études etudes.sup3@fmed.ulaval.ca Pédagogie universitaire en sciences de la santé Sciences cliniques et biomédicales Sciences de la réadaptation Prévention et gestion de la santé et de la sécurité au travail