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Découvrez nos professeurs et professeures!

Laetitia Michou

Médecin clinicienne enseignante agrégée

Laetitia Michou
Centre de recherche du CHU de Québec - Université Laval
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Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Pédagogie des sciences de la santé
Perte d’autonomie et réadaptation
Reproduction, génétique, périnatalité et développement
Transfert des connaissances

Domaines et intérêts de recherche du (de la) professeur(e) :

Appareil locomoteur et arthrite
  • Tissu osseux
  • Ostéoporose
  • Maladies du tissu osseux
  • Déformation musculosquelettique
Génétique humaine
  • Maladies génétiques
  • Marqueurs génétiques
  • Génomique
  • Phénotype
  • Gènes de susceptibilité
  • Mutation (processus)
  • Polymorphisme
  • Interactions gènes et environnement

Projets de recherche

  • Centre de recherche en arthrite (ARThrite) - Université Laval - Fonds internes - BDR - Centres de recherche reconnus, co-chercheur - 2020-11-03 au 2026-04-30
  • Fonds institutionnel d'exploitation des infrastructures pour l'Université Laval - Fondation Canadienne pour l'innovation (La) - Fonds d'exploitation des infrastructures (FEI), co-chercheur - 2002-04-01 au 2025-03-31
  • Impact fonctionnel d’un variant rare du gène WNT1 en présence de bisphosphonates in vitro dans les trois principaux types de cellules osseuses - CHU de Québec – Université Laval – CHUL - Subvention de fonctionnement de centre, chercheur principal - 2021-09-08 au 2022-03-31
  • Caractérisation de biomarqueurs pour une médecine de précision en rhumatologie - Fonds de recherche du Québec - Santé - Chercheurs-boursiers cliniciens - Juniors 1 et 2, Seniors, chercheur principal - 2017-07-01 au 2021-06-30
  • Développement d'un cours en ligne accrédité sur la médecine de précision destiné aux rhumatologues et résidents en rhumatologie de la province de Québec - Association des médecins rhumatologues du Québec, chercheur principal - 2020-09-09 au 2021-03-31
  • Financement d'un projet de recherche clinique en rhumatologie - Fondation du CHU de Québec, chercheur principal - 2020-07-20 au 2021-03-31
  • Financement pour projet de recherche clinique en rhumatologie, mai 2020 - Fondation du CHU de Québec, chercheur principal - 2020-05-14 au 2021-03-31
  • Support of Rheumatic Health Units Competition - La société d'arthrite, chercheur principal - 2016-09-01 au 2020-08-31
  • RSBO - Rémunération Mariam Dessay - Fonds de recherche du Québec - Santé - Réseaux thématiques de recherche, chercheur principal - 2019-09-01 au 2020-08-31
  • Étude prospective randomisée multicentrique sur le traitement anti-TNFa en période péri-opératoire et le risque d'infection lors de chirurgies électives du pied et de la cheville chez des patients avec polyarthrite rhumatoïde. - Université Laval - Fonds internes, Fondation pour l'avancement et la recherche en orthopédie du Québec, Fondation de l'Université Laval, co-chercheur - 2015-05-01 au 2020-03-31
  • Clinical validity and clinical utility of a screening test for Paget's disease of bone - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2019-03-01 au 2020-03-31
  • Financement du projet pilote de recherche clinique en rhumatologie - Fondation du CHU de Québec, chercheur principal - 2019-03-20 au 2020-03-31
  • Centre de recherche en arthrite de l'Université Laval - Université Laval - Fonds internes - BDR - Entités de recherche en émergence, co-chercheur - 2019-01-01 au 2020-01-31

Publications

  • Duration-Dependent Increase of Human Bone Matrix Mineralization in Long-Term Bisphosphonate Users with Atypical Femur Fracture, Farlay, D., Rizzo, S., Ste-Marie, L.-G., Michou, L., Morin, S.N., Qiu, S., Chavassieux, P., Chapurlat, R.D., Rao, S.D., Brown, J.P., Boivin, G., Journal of Bone and Mineral Research, 2021, 10.1002/jbmr.4244
  • Expression of the myeloid inhibitory receptor CLEC12A correlates with disease activity and cytokines in early rheumatoid arthritis, Vaillancourt, M., Desaulniers, P., Paré, G., Pagé, N., Lachhab, A., Kerever, A., Julien, A.-S., Amiable, N., Pelletier, M., Tessier, P.A., Bessette, L., Michou, L., Fortin, P.R., Fernandes, M.J., Scientific Reports, 2021, 10.1038/s41598-021-90631-7
  • Breast cancer and microcalcifications: An osteoimmunological disorder?, Clemenceau, A., Michou, L., Diorio, C., Durocher, F., International Journal of Molecular Sciences, 2020, 10.3390/ijms21228613
  • Clinical phenotype of adult offspring carriers of the p.Pro392Leu mutation within the SQSTM1 gene in Paget's disease of bone, Dessay, M., Jobin Gervais, F., Simonyan, D., Samson, A., Gleeton, G., Gagnon, E., Albert, C., Brown, J.P., Michou, L., Bone Reports, 2020, 10.1016/j.bonr.2020.100717
  • What are the rheumatology educational preferences of family medicine residents? A descriptive study, Lagacé, S., Julien, A.-S., Rheault, C., Bessette, L., Michou, L., Clinical Rheumatology, 2020, 10.1007/s10067-020-05018-2
  • A novel nonsense variant in SUPT20H gene associated with Rheumatoid Arthritis identified by Whole Exome Sequencing of multiplex families, Maëva Veyssiere, Javier Perea, Laetitia Michou, Anne Boland, Christophe Caloustian, Robert Olaso, Jean-François Deleuze, François Cornelis, Elisabeth Petit-Teixeira, Valérie Chaudru, PLOS ONE, 2019, 10.1371/journal.pone.0213387
  • Clinical peripheral enthesitis in the DESIR prospective longitudinal axial spondyloarthritis cohort, Nadon, V., Moltó, A., Etcheto, A., Bessette, L., Michou, L., D'Agostino, M.-A., Claudepierre, P., Wendling, D., Haraoui, P., Dougados, M., Clinical and experimental rheumatology, 2019
  • Effects of Biliopancreatic Diversion on Bone Turnover Markers and Association with Hormonal Factors in Patients with Severe Obesity, Turcotte, A.-F., Grenier-Larouche, T., Ung, R.-V., Simonyan, D., Carreau, A.-M., Carpentier, A.C., Mac-Way, F., Michou, L., Tchernof, A., Biertho, L., Lebel, S., Marceau, S., Gagnon, C., Obesity Surgery, 2019, 10.1007/s11695-018-3617-x
  • Gene-environment interactions in Paget's disease of bone, Numan, M.S., Jean, S., Dessay, M., Gagnon, E., Amiable, N., Brown, J.P., Michou, L., Joint Bone Spine, 2019, 10.1016/j.jbspin.2018.12.007
  • Has Paget's bone disease become rare?, Michou, L., Orcel, P., Joint Bone Spine, 2019, 10.1016/j.jbspin.2019.01.015
  • Has Paget's disease become a rare bone disease?,La maladie de Paget est-elle devenue une maladie osseuse rare ?, Michou, L., Orcel, P., Revue du Rhumatisme Monographies, 2019, 10.1016/j.monrhu.2018.11.008
  • Prevalence and Characteristics of Atypical Periprosthetic Femoral Fractures, Leclerc, J.-T., Michou, L., Vaillancourt, F., Pelet, S., Simonyan, D., Belzile, E.L., Journal of Bone and Mineral Research, 2019, 10.1002/jbmr.3584
  • A novel nonsense variant in SUPT20H gene associated with Rheumatoid Arthritis identified by Whole Exome Sequencing of multiplex families, Maëva Veyssiere, Javier Perea, Laetitia Michou, Anne Boland, Christophe Caloustian, Robert Olaso, Robert Olaso, Jean-François Deleuze, François Cornelis, Elisabeth Petit-Teixeira, Valérie Chaudru, 2018, 10.1101/430223
  • Molecular effect of an OPTN common variant associated to Paget's disease of bone, Iris A. L. Silva, Natércia Conceição, Édith Gagnon, Jacques P. Brown, M. Leonor Cancela, Laëtitia Michou, PLOS ONE, 2018, 10.1371/journal.pone.0197543
  • Effect of genetic variants of OPTN in the pathophysiology of Paget's disease of bone, Silva, I.A.L., Conceição, N., Gagnon, É., Caiado, H., Brown, J.P., Gianfrancesco, F., Michou, L., Cancela, M.L., Biochimica et Biophysica Acta - Molecular Basis of Disease, 2018, 10.1016/j.bbadis.2017.10.008
  • Environmental factors associated with familial or non-familial forms of Paget's disease of bone,Facteurs environnementaux associés aux formes familiales et non familiales de maladie osseuse de Paget, Audet, M.-C., Jean, S., Beaudoin, C., Guay-Bélanger, S., Dumont, J., Brown, J.P., Michou, L., Revue du Rhumatisme (Edition Francaise), 2018, 10.1016/j.rhum.2017.09.006
  • Epigenetics of bone diseases, Michou, L., Joint Bone Spine, 2018, 10.1016/j.jbspin.2017.12.003
  • Epigenetics of bone diseases,Épigénétique des maladies osseuses, Michou, L., Revue du Rhumatisme (Edition Francaise), 2018, 10.1016/j.rhum.2017.11.008
  • High bone mass in adults, Paccou, J., Michou, L., Kolta, S., Debiais, F., Cortet, B., Guggenbuhl, P., Joint Bone Spine, 2018, 10.1016/j.jbspin.2018.01.007
  • High bone mass in adults,Les hyperdensités osseuses de l'adulte, Paccou, J., Michou, L., Kolta, S., Debiais, F., Cortet, B., Guggenbuhl, P., Revue du Rhumatisme (Edition Francaise), 2018, 10.1016/j.rhum.2017.11.010
  • Sharing ongoing care with primary care physicians opens up opportunity for timelier and earlier care by rheumatologists for patients with new inflammatory polyarthritis, Nguyen, P., Julien, A.-S., Bessette, L., Fortin, P.R., Michou, L., Journal of Rheumatology, 2018, 10.3899/jrheum.170494
  • Effect of a rare genetic variant of TM7SF4 gene on osteoclasts of patients with Paget’s disease of bone, Emilie Laurier, Nathalie Amiable, Edith Gagnon, Jacques P. Brown, Laëtitia Michou, BMC Medical Genetics, 2017, 10.1186/s12881-017-0495-3
  • Environmental factors associated with familial or non-familial forms of Paget's disease of bone, Audet, M.-C., Jean, S., Beaudoin, C., Guay-Bélanger, S., Dumont, J., Brown, J.P., Michou, L., Joint Bone Spine, 2017, 10.1016/j.jbspin.2016.11.010
  • Assessment of femur geometrical parameters using EOS™ imaging technology in patients with atypical femur fractures; preliminary results, Morin, S.N., Wall, M., Belzile, E.L., Godbout, B., Moser, T.P., Michou, L., Ste-Marie, L.-G., de Guise, J.A., Rahme, E., Brown, J.P., Bone, 2016, 10.1016/j.bone.2015.10.016
  • Bilateral distal fibula fractures in a woman on long-term bisphosphonate therapy, Murray, J.C., Audet, M.C., Bédard, M., Michou, L., Osteoporosis International, 2016, 10.1007/s00198-015-3396-3
  • Change in fracture risk and fracture pattern after bariatric surgery: Nested case-control study, Rousseau, C., Jean, S., Gamache, P., Lebel, S., Mac-Way, F., Biertho, L., Michou, L., Gagnon, C., BMJ (Online), 2016, 10.1136/bmj.i3794
  • Development of a molecular test of Paget's disease of bone, Guay-Bélanger, S., Simonyan, D., Bureau, A., Gagnon, E., Albert, C., Morissette, J., Siris, E.S., Orcel, P., Brown, J.P., Michou, L., Bone, 2016, 10.1016/j.bone.2016.01.007
  • Incidence and Characteristics of Atypical Femoral Fractures: Clinical and Geometrical Data, Mahjoub, Z., Jean, S., Leclerc, J.-T., Brown, J.P., Boulet, D., Pelet, S., Grondin, C., Dumont, J., Belzile, É.L., Michou, L., Journal of Bone and Mineral Research, 2016, 10.1002/jbmr.2748
  • Measles virus nucleocapsid protein increases osteoblast differentiation in Paget's disease, Teramachi, J., Nagata, Y., Mohammad, K., Inagaki, Y., Ohata, Y., Guise, T., Michou, L., Brown, J.P., Windle, J.J., Kurihara, N., Roodman, G.D., Journal of Clinical Investigation, 2016, 10.1172/JCI82012
  • Paget's Disease of Bone: Prognosis and Complications, Michou, L., Brown, J.P., Advances in Pathobiology and Management of Paget's Disease of Bone, 2016, 10.1016/B978-0-12-805083-5.00008-7
  • The changing countenance of Paget's Disease of bone, Michou, L., Orcel, P., Joint Bone Spine, 2016, 10.1016/j.jbspin.2016.02.011
  • ZNF687 Mutations in Severe Paget Disease of Bone Associated with Giant Cell Tumor, Divisato, G., Formicola, D., Esposito, T., Merlotti, D., Pazzaglia, L., Del Fattore, A., Siris, E., Orcel, P., Brown, J.P., Nuti, R., Strazzullo, P., Benassi, M.S., Cancela, M.L., Michou, L., Rendina, D., Gennari, L., Gianfrancesco, F., American Journal of Human Genetics, 2016, 10.1016/j.ajhg.2015.12.016
  • Assessment of the educational impact of an information leaflet on the knowledge of complications in systemic sclerosis, Ikic, A., Beaudoin, C., Brown, J.P., Bessette, L., Fortin, P.R., Michou, L., Joint Bone Spine, 2015, 10.1016/j.jbspin.2014.12.005
  • Assessment of the educational impact of an information leaflet on the knowledge of complications in systemic sclerosis,Évaluation de l'impact d'une brochure d'information sur la connaissance des complications dans la sclérodermie systémique, Ikic, A., Beaudoin, C., Brown, J.P., Bessette, L., Fortin, P.R., Michou, L., Revue du Rhumatisme (Edition Francaise), 2015, 10.1016/j.rhum.2015.04.001
  • Detection of SQSTM1/P392L post-zygotic mutations in Paget’s disease of bone, Guay-Bélanger, S., Picard, S., Gagnon, E., Morissette, J., Siris, E.S., Orcel, P., Brown, J.P., Michou, L., Human Genetics, 2015, 10.1007/s00439-014-1488-3
  • Impact of air pollutants on oxidative stress in common autophagy-mediated aging diseases, Numan, M.S., Brown, J.P., Michou, L., International Journal of Environmental Research and Public Health, 2015, 10.3390/ijerph120202289
  • Paget's bone disease, an evanescent condition?,La maladie osseuse de Paget, une condition évanescente ?, Guay-Bélanger, S., Cormier, J.-G., Michou, L., Revue du Rhumatisme (Edition Francaise), 2015, 10.1016/j.rhum.2014.10.006
  • Paget's disease of bone: A disease with declining prevalence?,La maladie osseuse de Paget : une maladie en voie de disparition ?, Michou, L., Orcel, P., Revue du Rhumatisme (Edition Francaise), 2015, 10.1016/S1169-8330(16)30067-9
  • Paget’s disease of bone: An osteoimmunological disorder?, Numan, M.S., Amiable, N., Brown, J.P., Michou, L., Drug Design, Development and Therapy, 2015, 10.2147/DDDT.S88845
  • Alternative splicing in osteoclasts and Paget's disease of bone, Klinck, R., Laberge, G., Bisson, M., McManus, S., Michou, L., Brown, J.P., Roux, S., BMC Medical Genetics, 2014, 10.1186/s12881-014-0098-1
  • Can zebrafish be a valid model to study Paget's disease of bone?, Silva, I.A.L., Conceição, N., Michou, L., Cancela, M.L., Journal of Applied Ichthyology, 2014, 10.1111/jai.12523
  • Genetics of low back pain,Génétique des lombalgies, Michou, L., Revue du Rhumatisme Monographies, 2014, 10.1016/j.monrhu.2013.07.001
  • Identification of rare genetic variants in novel loci associated with Paget's disease of bone, Beauregard, M., Gagnon, E., Guay-Bélanger, S., Morissette, J., Brown, J.P., Michou, L., Human Genetics, 2014, 10.1007/s00439-013-1409-x
  • Association study of the platelet collagen receptor glycoprotein VI gene with rheumatoid arthritis, Michou, L., Cornélis, F., Baron, M., Bombardieri, S., Balsa, A., Westhovens, R., Barrera, P., Alves, H., Radstake, T.R.D.J., Migliorini, P., Bardin, T., Petit-Teixeira, E., Boilard, E., Clinical and Experimental Rheumatology, 2013
  • Genetic association study of dickkopf-1 and sclerostin genes with paget disease of bone, Beauregard, M., Gagnon, E., Guay-Bélanger, S., Siris, E.S., Morissette, J., Brown, J.P., Michou, L., Calcified Tissue International, 2013, 10.1007/s00223-013-9762-2
  • HLA shared epitope and ACPA: Just a marker or an active player?, Pratesi, F., Petit Teixeira, E., Sidney, J., Michou, L., Puxeddu, I., Sette, A., Cornelis, F., Migliorini, P., Autoimmunity Reviews, 2013, 10.1016/j.autrev.2013.08.002
  • Role of ATF7-TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease, Teramachi, J., Hiruma, Y., Ishizuka, S., Ishizuka, H., Brown, J.P., Michou, L., Cao, H., Galson, D.L., Subler, M.A., Zhou, H., Dempster, D.W., Windle, J.J., Roodman, G.D., Kurihara, N., Journal of Bone and Mineral Research, 2013, 10.1002/jbmr.1884
  • A genetic association study of the CLEC12A gene in rheumatoid arthritis, Michou, L., Cornélis, F., Levesque, J.-M., Bombardieri, S., Balsa, A., Westhovens, R., Barrera, P., Alves, H., van de Putte, L., Migliorini, P., Bardin, T., Petit-Teixeira, E., Fernandes, M.J.G., Joint Bone Spine, 2012, 10.1016/j.jbspin.2011.12.012
  • Epidemiogenetic study of French families with Paget's disease of bone, Michou, L., Collet, C., Morissette, J., Audran, M., Thomas, T., Gagnon, E., Launay, J.-M., Laplanche, J.-L., Brown, J.P., Orcel, P., Joint Bone Spine, 2012, 10.1016/j.jbspin.2011.07.005
  • Epidemiogenetic study of French families with Paget's disease of bone,Étude épidémiogénétique de familles françaises avec maladie osseuse de Paget, Michou, L., Collet, C., Morissette, J., Audran, M., Thomas, T., Gagnon, E., Launay, J.-M., Laplanche, J.-L., Brown, J.P., Orcel, P., Revue du Rhumatisme (Edition Francaise), 2012, 10.1016/j.rhum.2011.07.007
  • Genetic association study of UCMA/GRP and OPTN genes (PDB6 locus) with Paget's disease of bone, Michou, L., Conceição, N., Morissette, J., Gagnon, E., Miltenberger-Miltenyi, G., Siris, E.S., Brown, J.P., Cancela, M.L., Bone, 2012, 10.1016/j.bone.2012.06.028
  • Genetic study: Association of the CLEC12A gene with rheumatoid arthritis,Étude génétique: association du gène CLEC12A avec la polyarthrite rhumatoïde, Michou, L., Cornélis, F., Levesque, J.-M., Bombardieri, S., Balsa, A., Westhovens, R., Barrera, P., Alves, H., Van De Putte, L., Migliorini, P., Bardin, T., Petit-Teixeira, É., Fernandes, M.J.G., Revue du Rhumatisme (Edition Francaise), 2012, 10.1016/j.rhum.2012.02.009
  • Genetics of Dupuytren's disease, Michou, L., Lermusiaux, J.-L., Teyssedou, J.-P., Bardin, T., Beaudreuil, J., Petit-Teixeira, E., Joint Bone Spine, 2012, 10.1016/j.jbspin.2011.05.027
  • Contributions of the measles virus nucleocapsid gene and the SQSTM1/p62P392L mutation to paget's disease, Kurihara, N., Hiruma, Y., Yamana, K., Michou, L., Rousseau, C., Morissette, J., Galson, D.L., Teramachi, J., Zhou, H., Dempster, D.W., Windle, J.J., Brown, J.P., Roodman, G.D., Cell Metabolism, 2011, 10.1016/j.cmet.2010.12.002
  • Emerging strategies and therapies for treatment of paget's disease of bone, Michou, L., Brown, J.P., Drug Design, Development and Therapy, 2011, 10.2147/DDDT.S11306
  • Genetics of bone diseases: Paget's disease, fibrous dysplasia, osteopetrosis, and osteogenesis imperfecta, Michou, L., Brown, J.P., Joint Bone Spine, 2011, 10.1016/j.jbspin.2010.07.010
  • Genetics of digital osteoarthritis, Michou, L., Joint Bone Spine, 2011, 10.1016/j.jbspin.2010.09.012
  • Genetics of digital osteoarthritis,Génétique de l'arthrose digitale, Michou, L., Revue du Rhumatisme (Edition Francaise), 2011, 10.1016/j.rhum.2010.08.002
  • Genetics of Dupuytren's disease,Génétique de la maladie de Dupuytren, Michou, L., Lermusiaux, J.-L., Teyssedou, J.-P., Bardin, T., Beaudreuil, J., Petit-Teixeira, E., Revue du Rhumatisme (Edition Francaise), 2011, 10.1016/j.rhum.2011.03.013
  • Mutations of the cystic fibrosis gene in patients with bronchiectasis associated with rheumatoid arthritis, Puéchal, X., Bienvenu, T., Génin, E., Berthelot, J.-M., Sibilia, J., Gaudin, P., Marcelli, C., Lasbleiz, S., Michou, L., Cornélis, F., Kahan, A., Dusser, D.J., Annals of the Rheumatic Diseases, 2011, 10.1136/ard.2010.142760
  • Novel SQSTM1 mutations in patients with Paget's disease of bone in an unrelated multiethnic American population, Michou, L., Morissette, J., Gagnon, E.R., Marquis, A., Dellabadia, M., Brown, J.P., Siris, E.S., Bone, 2011, 10.1016/j.bone.2010.11.004
  • Erratum to Gene expression profile in osteoclasts from patients with Paget's disease of bone [Bone 46, (2010), 598-603], Michou, L., Chamoux, E., Couture, J., Morissette, J., Brown, J.P., Roux, S., Bone, 2010, 10.1016/j.bone.2010.02.023
  • Gene expression profile in osteoclasts from patients with Paget's disease of bone, Michou, L., Chamoux, E., Couture, J., Morissette, J., Brown, J.P., Roux, S., Bone, 2010, 10.1016/j.bone.2009.11.012
  • Genetics of bone diseases,Génétique des maladies osseuses, Michou, L., Brown, J.P., Revue du Rhumatisme Monographies, 2010, 10.1016/j.monrhu.2010.04.022
  • When to refer to genetic consultation?,Quand demander un avis génétique ?, Michou, L., Revue du Rhumatisme Monographies, 2010, 10.1016/j.monrhu.2010.06.003
  • Association study of the RANK locus in white European rheumatoid arthritis families, Teixeira, V.H., Dieudé, P., Michou, L., Migliorini, P., Balsa, A., Westhovens, R., Barrera, P., Alves, H., Vaz, C., Fernandes, M., Pascual-Salcedo, D., Bombardieri, S., Dequeker, J., Radstake, T.R., Van Riel, P., Van De Putte, L., Lopes-Vaz, A., Bardin, T., Cornélis, F., Petit-Teixeira, E., Annals of the Rheumatic Diseases, 2009, 10.1136/ard.2008.095380
  • Associations between genetic factors, tobacco smoking and autoantibodies in familial and sporadic rheumatoid arthritis, Michou, L., Teixeira, V.H., Pierlot, C., Lasbleiz, S., Bardin, T., Dieudé, P., Prum, B., Cornélis, F., Petit-Teixeira, E., Annals of the Rheumatic Diseases, 2008, 10.1136/ard.2007.075622
  • Lack of linkage and association of adrenomedulin and its receptor genes in French Caucasian rheumatoid arthritis trio families, Michou, L., Garnier, S., Barbet, S., Glikmans, E., Ea, H.-K., Uzan, B., Asensio, C., Ah Kioon, M.-D., Lasbleiz, S., Bardin, T., Cornélis, F., Lioté, F., Clinical and Experimental Rheumatology, 2008
  • Prevalence and distribution of autoimmune diseases in 368 rheumatoid arthritis families, Michou, L., Rat, A.-C., Lasbleiz, S., Bardin, T., Cornélis, F., Journal of Rheumatology, 2008
  • Replication of the tumor necrosis factor receptor-associated factor 1/complement component 5 region as a susceptibility locus for rheumatoid arthritis in a european family-based study, Kurreeman, F.A.S., Rocha, D., Houwing-Duistermaat, J., Vrijmoet, S., Teixeira, V.H., Migliorini, P., Balsa, A., Westhovens, R., Barrera, P., Alves, H., Vaz, C., Fernandes, M., Pascual-Salcedo, D., Michou, L., Bombardieri, S., Radstake, T., Van Riel, P., Van De Putte, L., Lopes-Vaz, A., Prum, B., Bardin, T., Gut, I., Cornelis, F., Huizinga, T.W.J., Petit-Teixeira, E., Toes, R.E.M., Arthritis and Rheumatism, 2008, 10.1002/art.23793
  • Septic arthritis of the hip with psoas abscess caused by Non-typhi Salmonella infection in an immunocompetent patient, Compain, C., Michou, L., Orcel, P., Hannouche, D., Richette, P., Joint Bone Spine, 2008, 10.1016/j.jbspin.2007.01.042
  • Septic arthritis of the hip with psoas abscess caused by non-typhi salmonella infection in an immunocompetent patient,Arthrite septique de hanche avec abcès du psoas due à une salmonelle non typhique chez un sujet immunocompétent, Compain, C., Michou, L., Orcel, P., Hannouche, D., Richette, P., Revue du Rhumatisme (Edition Francaise), 2008, 10.1016/j.rhum.2007.02.032
  • HSPD1 is not a major susceptibility gene for rheumatoid arthritis in the French Caucasian population, Jacq, L., Teixeira, V.H., Garnier, S., Michou, L., Dieudé, P., Rocha, D., Pierlot, C., Lemaire, I., Quillet, P., Hilliquin, P., Mbarek, H., Petit-Teixeira, E., Cornélis, F., Journal of Human Genetics, 2007, 10.1007/s10038-007-0201-y
  • IRF5 rs2004640-T allele, the new genetic factor for systemic lupus erythematosus, is not associated with rheumatoid arthritis, Garnier, S., Dieudé, P., Michou, L., Barbet, S., Tan, A., Lasbleiz, S., Bardin, T., Prum, B., Cornélis, F., Annals of the Rheumatic Diseases, 2007, 10.1136/ard.2006.061390
  • Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene, Michou, L., Lasbleiz, S., Rat, A.-C., Migliorini, P., Balsa, A., Westhovens, R., Barrera, P., Alves, H., Pierlot, C., Glikmans, E., Garnier, S., Dausset, J., Vaz, C., Fernandes, M., Petit-Teixeira, E., Lemaire, I., Pascual-Salcedo, D., Bombardieri, S., Dequeker, J., Radstake, T.R., Van Riel, P., Van De Putte, L., Lopes-Vaz, A., Prum, B., Bardin, T., Dieudé, P., Cornélis, F., Charron, D., Fauré, S., Kuntz, D., Martinez, M., Prud'homme, J.-F., Weissenbach, J., Spyropoulou, M., Stravopoulos, C., Proceedings of the National Academy of Sciences of the United States of America, 2007, 10.1073/pnas.0610250104
  • Molecular analysis of Paget's disease of bone,Analyse moléculaire de la maladie osseuse de Paget, Michou, L., Collet, C., Orcel, P., Pathologie Biologie, 2007, 10.1016/j.patbio.2006.06.005
  • Paget's disease of bone in the French population: Novel SQSTM1 mutations, functional analysis, and genotype-phenotype correlations, Collet, C., Michou, L., Audran, M., Chasseigneaux, S., Hilliquin, P., Bardin, T., Lemaire, I., Cornélis, F., Launay, J.-M., Orcel, P., Laplanche, J.-L., Journal of Bone and Mineral Research, 2007, 10.1359/jbmr.061106
  • The ITGAV rs3738919-C allele is associated with rheumatoid arthritis in the European Caucasian population: A family-based study, Jacq, L., Garnier, S., Dieudé, P., Michou, L., Pierlot, C., Migliorini, P., Balsa, A., Westhovens, R., Barrera, P., Alves, H., Vaz, C., Fernandes, M., Pascual-Salcedo, D., Bombardieri, S., Dequeker, J., Radstake, T.R., Van Riel, P., van de Putte, L., Lopes-Vaz, A., Glikmans, E., Barbet, S., Lasbleiz, S., Lemaire, I., Quillet, P., Hilliquin, P., Teixeira, V.H., Petit-Teixeira, E., Mbarek, H., Prum, B., Bardin, T., Cornélis, F., Arthritis Research and Therapy, 2007, 10.1186/ar2221
  • The TNFRSF1A R92Q mutation is frequent in rheumatoid arthritis but shows no evidence for association or linkage with the disease, Dieudé, P., Goossens, M., Cornélis, F., Michou, L., Bardin, T., Tchernitchko, D.O., Annals of the Rheumatic Diseases, 2007, 10.1136/ard.2006.060764
  • Genetics of Paget's disease of bone, Michou, L., Collet, C., Laplanche, J.-L., Orcel, P., Cornélis, F., Joint Bone Spine, 2006, 10.1016/j.jbspin.2005.05.009
  • Genetics of Paget's disease of bone {lozenge, open}{lozenge, open}Pour citer cet article, utiliser ce titre en anglais et sa référence dans le même volume de Joint Bone Spine.,Génétique de la maladie de Paget, Michou, L., Collet, C., Laplanche, J.-L., Orcel, P., Cornélis, F., Revue du Rhumatisme (Edition Francaise), 2006, 10.1016/j.rhum.2005.05.015
  • Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis, Michou, L., Croiseau, P., Petit-Teixeira, E., du Montcel, S.T., Lemaire, I., Pierlot, C., Osorio, J., Frigui, W., Lasbleiz, S., Quillet, P., Bardin, T., Prum, B., Clerget-Darpoux, F., Cornélis, F., Arthritis Research and Therapy, 2006, 10.1186/ar1949
  • Association study of VDR gene with rheumatoid arthritis in the French population, Maalej, A., Petit-Teixeira, E., Michou, L., Rebai, A., Cornelis, F., Ayadi, H., Genes and Immunity, 2005, 10.1038/sj.gene.6364260
  • New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility, Tezenas Du Montcel, S., Michou, L., Petit-Teixeira, E., Osorio, J., Lemaire, I., Lasbleiz, S., Pierlot, C., Quillet, P., Bardin, T., Prum, B., Cornelis, F., Clerget-Darpoux, F., Arthritis and Rheumatism, 2005, 10.1002/art.20989
  • Rheumatoid arthritis seropositive for the rheumatoid factor is linked to the protein tyrosine phosphatase nonreceptor 22-620W allele., Dieudé, P., Garnier, S., Michou, L., Petit-Teixeira, E., Glikmans, E., Pierlot, C., Lasbleiz, S., Bardin, T., Prum, B., Cornélis, F., Arthritis research & therapy, 2005
  • Dense genome-wide linkage analysis of rheumatoid arthritis, including covariates, Osorio Y Fortéa, J., Bukulmez, H., Petit-Teixeira, E., Michou, L., Pierlot, C., Cailleau-Moindrault, S., Lemaire, I., Lasbleiz, S., Alibert, O., Quillet, P., Bardin, T., Prum, B., Olson, J.M., Cornélis, F., Arthritis and Rheumatism, 2004, 10.1002/art.20458
  • Granulomatous synovitis after intra-articular Hylan GF-20. A report of two cases,Synovite granulomateuse après injection de hylane GF-20. À propos de deux cas, Michou, L., Job-Deslandre, C., de Pinieux, G., Kahan, A., Revue du Rhumatisme (Edition Francaise), 2004, 10.1016/j.rhum.2003.09.013
  • Granulomatous synovitis after intraarticular Hylan GF-20. A report of two cases, Michou, L., Job-Deslandre, C., De Pinieux, G., Kahan, A., Joint Bone Spine, 2004, 10.1016/j.jbspin.2003.09.006
  • Paget's disease of bone, Rousière, M., Michou, L., Cornélis, F., Orcel, P., Best Practice and Research: Clinical Rheumatology, 2003, 10.1016/j.berh.2003.09.003
  • Rapid efficacy of highly active antiretroviral therapy in a case of HIV myelitis, Michou, L., Sauve, C., Sereni, C., Lamotte, C., Maillard, A., Sereni, D., European Journal of Internal Medicine, 2002, 10.1016/S0953-6205(01)00193-5
  • Detection of SQSTM1/P392L post-zygotic mutations in Paget’s disease of bone, , 1911
  • Epidemiogenetic study of French families with Paget’s disease of bone, , 1911
  • Genetic association of Dickkopf 1 and Sclerostin genes with Paget’s disease of bone, , 1911
  • Genetic association study of UCMA/GRP and OPTN genes (PDB6 locus) with Paget’s disease of bone, , 1911
  • Identification of rare genetic variants in five novel loci associated with Paget’s disease of bone, , 1911

Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2009
  • Etienne Lavallée - Maitrîse avec mémoire - En cours
  • Ya Feng Yan - Maitrîse avec mémoire - En cours
  • Sabrina Guay-Bélanger - Doctorat - En cours
  • Lambert Kamla Wamba - Maitrîse avec mémoire - En cours
  • Mariejka Beauregard - Maitrîse avec mémoire - 2013/05
  • Mohamed Numan - Maitrîse avec mémoire - 2016/09
  • Mariam Dessay - Doctorat - 2020/05

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*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.

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Vice-décanat à la recherche et aux études supérieures
Pavillon Ferdinand-Vandry
Université Laval
1050, avenue de la Médecine,  local 4645
Québec, Québec G1V 0A6
Canada

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vdres@fmed.ulaval.ca

Jacques Simard
Vice-doyen à la recherche et aux études supérieures
vice-doyen.recherche-et-etudes-superieures@fmed.ulaval.ca

Louise Laperrière
Adjointe au vice-doyen à la recherche et aux études supérieures
louise.laperriere@fmed.ulaval.ca 

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