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Centre de recherche du CHU de Québec - Université Laval
Partager la fiche :
Contribution à la recherche
Axe de recherche de l'Université Laval :
Santé et bien-être durables
Thématiques de recherche de la Faculté de
médecine :
Médecine régénératrice et moléculaire
Neurosciences et santé mentale
Domaines et intérêts de recherche du (de la)
professeur(e) :
Appareil locomoteur et arthrite
Maladies musculaires
Lésions musculosquelettiques et réparations
Génétique humaine
Thérapie génique
Génétique moléculaire
Maladies génétiques
Neurosciences, santé mentale et toxicomanies
Maladie d'Alzheimer
Maladies neurodégénératives
Maladies neuromusculaires
Projets de recherche
Removal of the GAA repeat with the CRISPR/Cas9 system in Friedreich patient cells and in the YG8sR mouse model- CHU de Québec – Université Laval – CHUL - Développement de la recherche (FC), chercheur principal - 2022-02-06 au 2027-03-31
Removal of the GAA repeat with the CRISPR/Cas9 system in Friedreich patient cells and in the YG8sR mouse model- Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2019-10-01 au 2024-09-30
Development of an AAV library- Conseil national de recherches du Canada - Programmes et initiatives de R&D collaboratifs, chercheur principal - 2022-04-01 au 2024-03-31
PRIME editing correction of the T1709M mutation responsible for some cases of Ryanodine receptor type I-related myopathies- RYR-1 Foundation, chercheur principal - 2021-07-01 au 2023-06-30
Développement d’une thérapie génique pour l’ataxie de Friedreich- Ataxie Canada, chercheur principal - 2021-05-31 au 2023-05-31
Les cellules souches pluripotentes génétiquement corrigées comme thérapie pour l’epidermolyse bulleuse simplex- Fonds de recherche du Québec - Santé - Réseaux thématiques de recherche, Université du Québec à Chicoutimi - UQAC , co-chercheur - 2022-04-01 au 2023-03-31
Deciphering the role of DCIR in HIV-1 pathogenesis- Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2018-04-01 au 2023-03-31
Correction by CRISPR base editing of point mutations responsible for Duchenne Muscular Dystrophy- The Foundation for gene and cell therapy Jesse's Journey, chercheur principal - 2020-06-01 au 2022-05-31
Development of a rapid and simple test to detect the COVID-19 variants that can be used in remote areas and developing countries- Instituts de recherche en santé du Canada - Subvention de fonctionnement : Possibilité de financement sur les nouveaux besoins prioritaires en recherche sur la COVID-19, chercheur principal - 2021-06-01 au 2022-05-31
Phase I/II clinical trial of myoblast transplantation to Duchenne Muscular Dystrophy patients.- Instituts de recherche en santé du Canada - Subvention de fonctionnement, chercheur principal - 2013-10-01 au 2022-03-31
Utilisation de vésicules extracellulaires pour livrer les composants de la technologie d’édition du génome CRISPR/PRIME- Fonds de recherche du Québec - Santé - Réseaux thématiques de recherche, chercheur principal - 2021-04-01 au 2022-03-31
Génération de lignées isogéniques pour les mutations GNA11/BAP1 par « PRIME editing » comme modèles d’études du mélanome oculaire.- Fonds de recherche du Québec - Santé - Réseaux thématiques de recherche, co-chercheur - 2021-04-01 au 2022-03-31
Correction of the c. 121 A to T mutation in the NKX6-2 gene by PRIME editing- Ataxia UK, chercheur principal - 2021-01-26 au 2022-01-25
Using extracellular vesicles to deliver therapeutic proteins for various ataxia- National Ataxia Foundation - Research Seed Money, chercheur principal - 2020-03-01 au 2021-07-01
Association d'hydrogel et de pré-conditionnement pharmacologique pour améliorer la greffe de myoblastes- Fonds de recherche du Québec - Santé - Réseaux thématiques de recherche, chercheur principal - 2020-04-01 au 2021-03-31
Acquisition d'un congélateur à basse température (-80C) - Fondation du CHU de Québec, chercheur principal - 2020-10-09 au 2021-03-31
Development of a molecular therapies for Freidreich Ataxia.- Ataxie Canada, chercheur principal - 2013-01-01 au 2021-03-31
Development of a treatment of Alzheimer based on the editing of the Amyloid Precuror Protein gene with the CRISPR system.- Weston Brain institute - Transformational Research, chercheur principal - 2016-01-15 au 2020-09-30
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Publications
CRISPR-Cas9 Gene Therapy for Duchenne Muscular Dystrophy, , Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2022, 10.1007/s13311-022-01197-9
CRISPR-SCReT (CRISPR-Stop Codon Read Through) method to control Cas9 expression for gene editing, , Gene therapy, 2022, 10.1038/s41434-021-00297-z
Insertion of the Icelandic Mutation (A673T) by Prime Editing: A Potential Preventive Treatment for Familial and Sporadic Alzheimer's Disease, , The CRISPR journal, 2022, 10.1089/crispr.2021.0085
Serum Extracellular Vesicles for Delivery of Crispr-Cas9 Ribonucleoproteins to Modify the Dystrophin Gene, , Molecular therapy : the journal of the American Society of Gene Therapy, 2022, 10.1016/j.ymthe.2022.05.023
Therapeutic Strategies for Dystrophin Replacement in Duchenne Muscular Dystrophy, , Frontiers in medicine, 2022, 10.3389/fmed.2022.859930
Base editing strategy for insertion of the A673T mutation in the APP gene to prevent the development of AD in vitro, , Molecular therapy. Nucleic acids, 2021, 10.1016/j.omtn.2021.02.032
Current Clinical Applications of In Vivo Gene Therapy with AAVs, , Molecular therapy : the journal of the American Society of Gene Therapy, 2021, 10.1016/j.ymthe.2020.12.007
Myogenic progenitor cells derived from human induced pluripotent stem cell are immune-tolerated in humanized mice, , Stem cells translational medicine, 2021, 10.1002/sctm.19-0452
Three Decades of Clinical Gene Therapy: From Experimental Technologies to Viable Treatments, , Molecular therapy : the journal of the American Society of Gene Therapy, 2021, 10.1016/j.ymthe.2021.01.013
Base editing strategy allows insertion of the A673T mutation in APP gene to prevent the development of Alzheimer’s disease, Antoine Guyon, Joël Rousseau, Francis-Gabriel Bégin, Tom Bertin, Gabriel Lamothe, Jacques P. Tremblay, 2020, 10.1101/2020.10.27.357830
A Comment on Muscle Xenografts Reproduce Key Molecular Features of Facioscapulohumeral Muscular Dystrophy : What Is New and What Has Already been Done and Reported but Was Not Quoted?, , Cell transplantation, 2020, 10.1177/0963689720939120
Human Muscle Precursor Cells Form Human-Derived Myofibers in Skeletal Muscles of Nonhuman Primates: A Potential New Preclinical Setting to Test Myogenic Cells of Human Origin for Cell Therapy of Myopathies, , Journal of neuropathology and experimental neurology, 2020, 10.1093/jnen/nlaa110
The protective mutation A673T in amyloid precursor protein gene decreases Aβ peptides production for 14 forms of Familial Alzheimer's Disease in SH-SY5Y cells, , PloS one, 2020, 10.1371/journal.pone.0237122
Integration of a Raman spectroscopy system to a robotic-assisted surgical system for real-time tissue characterization during radical prostatectomy procedures, , Journal of biomedical optics, 2019, 10.1117/1.JBO.24.2.025001
Myotubes Formed De Novo by Myoblasts Injected into the Scar of Myocardial Infarction Persisted for 16 Years in a Patient: Importance for Regenerative Medicine in Degenerative Myopathies, , Stem cells translational medicine, 2019, 10.1002/sctm.18-0202
Sarcolemmal Complement Membrane Attack Complex Deposits During Acute Rejection of Myofibers in Nonhuman Primates, , Journal of neuropathology and experimental neurology, 2019, 10.1093/jnen/nly106
CRISPR-induced deletion with SaCas9 restores dystrophin expression in dystrophic models in vitro and in vivo, , 2018, 10.1101/378331
CRISPR-Induced Deletion with SaCas9 Restores Dystrophin Expression in Dystrophic Models In Vitro and In Vivo, , Molecular therapy : the journal of the American Society of Gene Therapy, 2018, 10.1016/j.ymthe.2018.08.010
From gRNA Identification to the Restoration of Dystrophin Expression: A Dystrophin Gene Correction Strategy for Duchenne Muscular Dystrophy Mutations Using the CRISPR-Induced Deletion Method, , Methods in molecular biology (Clifton, N.J.), 2018, 10.1007/978-1-4939-7374-3_19
Increased Frataxin Expression Induced in Friedreich Ataxia Cells by Platinum TALE-VP64s or Platinum TALE-SunTag, , Molecular therapy. Nucleic acids, 2018, 10.1016/j.omtn.2018.04.009
Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome, , Brain, behavior, and immunity, 2018, 10.1016/j.bbi.2018.06.007
Advances & challenges of using CRISPR-Cas9 gene editing for treating Duchenne muscular dystrophy, , Cell & gene therapy insights, 2017, 10.18609/cgti.2017.003
CD56+ Muscle Derived Cells but Not Retinal NG2+ Perivascular Cells of Nonhuman Primates are Myogenic after Intramuscular Transplantation in Immunodeficient Mice, , Journal of stem cell research & therapy, 2017, 10.4172/2157-7633.1000377
Cell Therapy in Myology: Dynamics of Muscle Precursor Cell Death after Intramuscular Administration in Non-human Primates, , Molecular therapy. Methods & clinical development, 2017, 10.1016/j.omtm.2017.05.002
De Novo Circulating Antidonor's Cell Antibodies During Induced Acute Rejection of Allogeneic Myofibers in Myogenic Cell Transplantation: A Study in Nonhuman Primates, , Transplantation direct, 2017, 10.1097/TXD.0000000000000740
Deletion of the GAA repeats from the human frataxin gene using the CRISPR-Cas9 system in YG8R-derived cells and mouse models of Friedreich ataxia, , Gene therapy, 2017, 10.1038/gt.2016.89
Increased Expression of Laminin Subunit Alpha 1 Chain by dCas9-VP160, , Molecular therapy. Nucleic acids, 2017, 10.1016/j.omtn.2016.11.004
The advances and challenges of Gene Therapy for Duchenne Muscular Dystrophy, , Journal of Genetic Medicine and Gene Therapy, 2017, 10.29328/journal.jgmgt.1001003
The Process of Engraftment of Myogenic Cells in Skeletal Muscles of Primates: Understanding Clinical Observations and Setting Directions in Cell Transplantation Research, , Cell transplantation, 2017, 10.1177/0963689717724798
Characterization of frataxin gene network in Friedreich's ataxia fibroblasts using the RNA-Seq technique, , Mitochondrion, 2016, 10.1016/j.mito.2016.06.003
Confirmation of donor-derived dystrophin in a duchenne muscular dystrophy patient allotransplanted with normal myoblasts, , Muscle & nerve, 2016, 10.1002/mus.25129
Development of an AAV9 coding for a 3XFLAG-TALEfrat#8-VP64 able to increase in vivo the human frataxin in YG8R mice, , Gene therapy, 2016, 10.1038/gt.2016.36
Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method, , Molecular therapy. Nucleic acids, 2016, 10.1038/mtna.2015.58
Gene Editing for Duchenne Muscular Dystrophy Using the CRISPR/Cas9 Technology: The Importance of Fine-tuning the Approach, , Molecular therapy : the journal of the American Society of Gene Therapy, 2016, 10.1038/mt.2016.191
Rational design of a serum-free culture medium for the growth of human myoblasts destined to cell therapy, , The Canadian journal of chemical engineering, 2016, 10.1002/cjce.22586
Cell therapy in muscular dystrophies: many promises in mice and dogs, few facts in patients, , Expert opinion on biological therapy, 2015, 10.1517/14712598.2015.1057564
Sensorimotor skills in Fxn KO/Mck mutants deficient for frataxin in muscle, , Brain research, 2015, 10.1016/j.brainres.2015.03.001
The CRISPR system can correct or modify the expression of genes responsible for hereditary diseases, , Medecine sciences : M/S, 2015, 10.1051/medsci/20153111016
Thérapie cellulaire et génique, , 2015
An AAV9 coding for frataxin clearly improved the symptoms and prolonged the life of Friedreich ataxia mouse models, , Molecular therapy. Methods & clinical development, 2014, 10.1038/mtm.2014.44
Clarifying misconceptions about myoblast transplantation in myology, , Molecular therapy : the journal of the American Society of Gene Therapy, 2014, 10.1038/mt.2014.57
Development of a web course on gene therapy by the international consortium of gene therapy, , Molecular therapy : the journal of the American Society of Gene Therapy, 2014, 10.1038/mt.2014.11
First study of intra-arterial delivery of myogenic mononuclear cells to skeletal muscles in primates, , Cell transplantation, 2014, 10.3727/096368914X685032
Generation of human endometrial knockout cell lines with the CRISPR/Cas9 system confirms the prostaglandin F2α synthase activity of aldo-ketoreductase 1B1, , Molecular human reproduction, 2014, 10.1093/molehr/gau023
Intramuscular transplantation of myogenic cells in primates: importance of needle size, cell number, and injection volume, , Cell transplantation, 2014, 10.3727/096368912X661337
Therapeutic effects of exon skipping and losartan on skeletal muscle of mdx mice, , Pathology international, 2014, 10.1111/pin.12190
Transplantation of Myogenic Cells in Duchenne Muscular Dystrophy Patients: Clinical Findings, , 2014, 10.1016/b978-0-12-410396-2.00026-8
A Potential New Therapeutic Approach for Friedreich Ataxia: Induction of Frataxin Expression With TALE Proteins, , Molecular therapy. Nucleic acids, 2013, 10.1038/mtna.2013.41
Assessment of a symptomatic Duchenne muscular dystrophy carrier 20 years after myoblast transplantation from her asymptomatic identical twin sister, , Neuromuscular disorders : NMD, 2013, 10.1016/j.nmd.2013.04.007
Effects of vitamin C on cytotherapy-mediated muscle regeneration, , Cell transplantation, 2013, 10.3727/096368912X657846
Electroporation as a method to induce myofiber regeneration and increase the engraftment of myogenic cells in skeletal muscles of primates, , Journal of neuropathology and experimental neurology, 2013, 10.1097/NEN.0b013e31829bac22
Myopathy in a rhesus monkey with biopsy findings similar to human sporadic inclusion body myositis, , Neuromuscular disorders : NMD, 2013, 10.1016/j.nmd.2012.10.020
Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients, , Molecular therapy : the journal of the American Society of Gene Therapy, 2013, 10.1038/mt.2013.111
Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation, , Molecular therapy. Nucleic acids, 2013, 10.1038/mtna.2012.55
Translating the genomics revolution: the need for an international gene therapy consortium for monogenic diseases, , Molecular therapy : the journal of the American Society of Gene Therapy, 2013, 10.1038/mt.2013.4
Administration of a soluble activin type IIB receptor promotes the transplantation of human myoblasts in dystrophic mice, , Cell transplantation, 2012, 10.3727/096368911X627480
AG490 improves the survival of human myoblasts in vitro and in vivo, , Cell transplantation, 2012, 10.3727/096368912X655028
Efficacy and site-specificity of adenoviral vector integration mediated by the phage φC31 integrase, , Human gene therapy methods, 2012, 10.1089/hgtb.2012.122
Fibrin gel improves the survival of transplanted myoblasts, , Cell transplantation, 2012, 10.3727/096368911X576018
Generation of lentiviral vectors for use in skeletal muscle research, , Methods in molecular biology (Clifton, N.J.), 2012, 10.1007/978-1-61779-343-1_16
Losartan enhances the success of myoblast transplantation, , Cell transplantation, 2012, 10.3727/096368911X576045
Macrophages improve survival, proliferation and migration of engrafted myogenic precursor cells into MDX skeletal muscle, , PloS one, 2012, 10.1371/journal.pone.0046698
Myoblast transplantation in skeletal muscles, , 2012
Myoblasts derived from normal hESCs and dystrophic hiPSCs efficiently fuse with existing muscle fibers following transplantation, , Molecular therapy : the journal of the American Society of Gene Therapy, 2012, 10.1038/mt.2012.188
Necrosis, sarcolemmal damage and apoptotic events in myofibers rejected by CD8+ lymphocytes: Observations in nonhuman primates, , Neuromuscular disorders : NMD, 2012, 10.1016/j.nmd.2012.05.005
Transcription activator-like effector proteins induce the expression of the frataxin gene, , Human gene therapy, 2012, 10.1089/hum.2012.034
Blocking the myostatin signal with a dominant negative receptor improves the success of human myoblast transplantation in dystrophic mice, , Molecular therapy : the journal of the American Society of Gene Therapy, 2011, 10.1038/mt.2010.171
Current status of pharmaceutical and genetic therapeutic approaches to treat DMD, , Molecular therapy : the journal of the American Society of Gene Therapy, 2011, 10.1038/mt.2011.59
Endonucleases: tools to correct the dystrophin gene, , The journal of gene medicine, 2011, 10.1002/jgm.1611
Gene transfer using HACs: a key step closer to ex vivo gene therapy using autologous gene-corrected cells to treat muscular dystrophy, , Molecular therapy : the journal of the American Society of Gene Therapy, 2011, 10.1038/mt.2011.254
Intramuscular cell transplantation as a potential treatment of myopathies: clinical and preclinical relevant data, , Expert opinion on biological therapy, 2011, 10.1517/14712598.2011.548800
Myoblast transplantation: techniques in nonhuman primates as a bridge to clinical trials, , 2011
Not an inside job: how can transplantation of relatively few exogenous satellite cells do what thousands of endogenous cells cannot?, , Molecular therapy : the journal of the American Society of Gene Therapy, 2011, 10.1038/mt.2010.276
Transplanted myoblasts can migrate several millimeters to fuse with damaged myofibers in nonhuman primate skeletal muscle, , Journal of neuropathology and experimental neurology, 2011, 10.1097/NEN.0b013e31822a6baa
A first semimanual device for clinical intramuscular repetitive cell injections, , Cell transplantation, 2010, 10.3727/096368909X478812
Dystrophin expression following the transplantation of normal muscle precursor cells protects mdx muscle from contraction-induced damage, , Cell transplantation, 2010, 10.3727/096368910X4863235
Electrotransfer of the full-length dog dystrophin into mouse and dystrophic dog muscles, , Human gene therapy, 2010, 10.1089/hum.2010.024
Expression of dog microdystrophin in mouse and dog muscles by gene therapy, , Molecular therapy : the journal of the American Society of Gene Therapy, 2010, 10.1038/mt.2010.23
Ganglioside GM3 levels are altered in a mouse model of HIBM: GM3 as a cellular marker of the disease, , PloS one, 2010, 10.1371/journal.pone.0010055
Implantation of myogenic cells in skeletal muscles, , 2010
Intramuscular transplantation of human postnatal myoblasts generates functional donor-derived satellite cells, , Molecular therapy : the journal of the American Society of Gene Therapy, 2010, 10.1038/mt.2010.128
Laminin-111: a potential therapeutic agent for Duchenne muscular dystrophy, , Molecular therapy : the journal of the American Society of Gene Therapy, 2010, 10.1038/mt.2010.165
Meganucleases can restore the reading frame of a mutated dystrophin, , Gene therapy, 2010, 10.1038/gt.2010.26
Myoblast Transplantation in skeletal muscles, , 2010
Myoblast transplantation: a possible surgical treatment for a severe pediatric disease, , Surgery today, 2010, 10.1007/s00595-009-4242-z
Past, present and future of myoblast transplantation in the treatment of Duchenne muscular dystrophy, , Pediatric transplantation, 2010, 10.1111/j.1399-3046.2010.01377.x
Percutaneous versus surgical delivery of autologous myoblasts after chronic myocardial infarction: an in vivo cardiovascular magnetic resonance study, , Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2010, 10.1002/ccd.22204
Preservation of muscle spindles in a 27-year-old Duchenne muscular dystrophy patient: importance for regenerative medicine strategies, , Muscle & nerve, 2010, 10.1002/mus.21644
The paracrine effect: pivotal mechanism in cell-based cardiac repair, , Journal of cardiovascular translational research, 2010, 10.1007/s12265-010-9198-2
A case for immunosuppression for myoblast transplantation in duchenne muscular dystrophy, , Molecular therapy : the journal of the American Society of Gene Therapy, 2009, 10.1038/mt.2009.125
Development and characterization of a simian virus 40 immortalized bovine endometrial stromal cell line, , Endocrinology, 2009, 10.1210/en.2008-0744
Gene Therapy in Duchenne’s Muscular Dystrophy, , 2009
Growth factor coinjection improves the migration potential of monkey myogenic precursors without affecting cell transplantation success, , Cell transplantation, 2009, 10.3727/096368909X470900
Overexpression of follistatin in human myoblasts increases their proliferation and differentiation, and improves the graft success in SCID mice, , Cell transplantation, 2009, 10.3727/096368909X470865
Another new super muscle stem cell leaves unaddressed the real problems of cell therapy for duchenne muscular dystrophy, , Molecular therapy : the journal of the American Society of Gene Therapy, 2008, 10.1038/mt.2008.243
Central tolerance to myogenic cell transplants does not include muscle neoantigens, , Transplantation, 2008, 10.1097/TP.0b013e31817726bc
Inhibiting myostatin with follistatin improves the success of myoblast transplantation in dystrophic mice, , Cell transplantation, 2008, 10.3727/096368908784153913
The first Joint Conference of the Cell Transplant Society (CTS), International Pancreas and Islet Transplant Association (IPITA), and International Xenotransplantation Association (IXA), all sections of The Transplantation Society (TTS), took place in Minneapolis, Minn, USA, from September 15-20, 2007. Preface, , Transplantation proceedings, 2008, 10.1016/j.transproceed.2008.02.021
Vascular endothelial growth factor reduced hypoxia-induced death of human myoblasts and improved their engraftment in mouse muscles, , Gene therapy, 2008, 10.1038/sj.gt.3303059
1,25-dihydroxyvitamin D3 increases the transplantation success of human muscle precursor cells in SCID mice, , Cell transplantation, 2007, 10.3727/000000007783464876
A new pro-migratory activity on human myogenic precursor cells for a synthetic peptide within the E domain of the mechano growth factor, , Experimental cell research, 2007, 10.1016/j.yexcr.2006.10.032
A synthetic mechano growth factor E Peptide enhances myogenic precursor cell transplantation success, , American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2007, 10.1111/j.1600-6143.2007.01927.x
Autologous transplantation of muscle precursor cells modified with a lentivirus for muscular dystrophy: human cells and primate models, , Molecular therapy : the journal of the American Society of Gene Therapy, 2007, 10.1038/sj.mt.6300047
Dystrophin expression in host muscle following transplantation of muscle precursor cells modified with the phiC31 integrase, , Gene therapy, 2007, 10.1038/sj.gt.3302887
Early and massive death of myoblasts transplanted into skeletal muscle : responsible factors and potential solutions, , Current opinion in organ transplantation, 2007
First test of a high-density injection protocol for myogenic cell transplantation throughout large volumes of muscles in a Duchenne muscular dystrophy patient: eighteen months follow-up, , Neuromuscular disorders : NMD, 2007, 10.1016/j.nmd.2006.10.003
Induction of Anoikis following myoblast transplantation into SCID mouse muscles requires the Bit1 and FADD pathways, , American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2007, 10.1111/j.1600-6143.2007.01830.x
Ischemic central necrosis in pockets of transplanted myoblasts in nonhuman primates: implications for cell-transplantation strategies, , Transplantation, 2007, 10.1097/01.tp.0000288322.94252.22
Stem and progenitor cells in skeletal muscle development, maintenance, and therapy, , Molecular therapy : the journal of the American Society of Gene Therapy, 2007, 10.1038/mt.sj.6300145
A Historic Recapitulation of Myoblast Transplantation, , 2006
CSCI/RCPSC Henry Friesen Lecture: Cell therapy for Duchenne muscular dystrophy, , Clinical and investigative medicine. Medecine clinique et experimentale, 2006
Decidualization and maintenance of a functional prostaglandin system in human endometrial cell lines following transformation with SV40 large T antigen, , Molecular human reproduction, 2006, 10.1093/molehr/gal034
Dystrophin expression in muscles of duchenne muscular dystrophy patients after high-density injections of normal myogenic cells, , Journal of neuropathology and experimental neurology, 2006, 10.1097/01.jnen.0000218443.45782.81
Ex vivo modification of cells to induce a muscle-based expression, , Current gene therapy, 2006, 10.2174/156652306779010651
Exercise improves the success of myoblast transplantation in mdx mice, , Neuromuscular disorders : NMD, 2006, 10.1016/j.nmd.2006.06.003
Induction of tolerance across fully mismatched barriers by a nonmyeloablative treatment excluding antibodies or irradiation use, , Cell transplantation, 2006, 10.3727/000000006783981521
Interleukin-4 improves the migration of human myogenic precursor cells in vitro and in vivo, , Experimental cell research, 2006, 10.1016/j.yexcr.2006.01.002
Myocardial regeneration : which cell and why, , 2006
Use of repeating dispensers to increase the efficiency of the intramuscular myogenic cell injection procedure, , Cell transplantation, 2006, 10.3727/000000006783981648
Improved success of myoblast transplantation in mdx mice by blocking the myostatin signal, , Transplantation, 2005, 10.1097/01.tp.0000167379.27872.2b
Real-time imaging of myoblast transplantation using the human sodium iodide symporter, , BioTechniques, 2005, 10.2144/05386IT01
Dystrophin expression in myofibers of Duchenne muscular dystrophy patients following intramuscular injections of normal myogenic cells, , Molecular therapy : the journal of the American Society of Gene Therapy, 2004, 10.1016/j.ymthe.2003.11.023
Endosome disruption enhances the functional nuclear delivery of Tat-fusion proteins, , Biochemical and biophysical research communications, 2004, 10.1016/j.bbrc.2004.04.180
Growth factors improve the in vivo migration of human skeletal myoblasts by modulating their endogenous proteolytic activity, , Transplantation, 2004, 10.1097/01.tp.0000131175.60047.eb
Myoblast survival enhancement and transplantation success improvement by heat-shock treatment in mdx mice, , Transplantation, 2004, 10.1097/01.tp.0000121503.01535.f5
Novel Duchenne muscular dystrophy treatment through myoblast transplantation tolerance with anti-CD45RB, anti-CD154 and mixed chimerism, , American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2004, 10.1111/j.1600-6143.2004.00501.x
Nucleofection of muscle-derived stem cells and myoblasts with phiC31 integrase: stable expression of a full-length-dystrophin fusion gene by human myoblasts, , Molecular therapy : the journal of the American Society of Gene Therapy, 2004, 10.1016/j.ymthe.2004.05.034
Cell therapies for inherited myopathies, , Current opinion in rheumatology, 2003, 10.1097/00002281-200311000-00007
Identification of a putative pathway for the muscle homing of stem cells in a muscular dystrophy model, , The Journal of cell biology, 2003, 10.1083/jcb.200210006
Myoblast transplantation: the current status of a potential therapeutic tool for myopathies, , Journal of muscle research and cell motility, 2003
Myogenesis: where and how can we get skeletal myoblasts?, , Dialogues in cardiovascular medicine : DCM, 2003
Resetting the problem of cell death following muscle-derived cell transplantation: detection, dynamics and mechanisms, , Journal of neuropathology and experimental neurology, 2003, 10.1093/jnen/62.9.951
Telomerase can extend the proliferative capacity of human myoblasts, but does not lead to their immortalization, , Molecular cancer research : MCR, 2003
Tubulyzine, a novel tri-substituted triazine, prevents the early cell death of transplanted myogenic cells and improves transplantation success, , Biochemistry and cell biology = Biochimie et biologie cellulaire, 2003, 10.1139/o03-054
Autotransplantation in mdx mice of mdx myoblasts genetically corrected by an HSV-1 amplicon vector, , Cell transplantation, 2002
Dynamics of the early immune cellular reactions after myogenic cell transplantation, , Cell transplantation, 2002, 10.3727/000000002783985378
Dysferlin expression after normal myoblast transplantation in SCID and in SJL mice, , Neuromuscular disorders : NMD, 2002, 10.1016/s0960-8966(01)00254-1
Efficacy of myoblast transplantation in nonhuman primates following simple intramuscular cell injections: toward defining strategies applicable to humans, , Experimental neurology, 2002, 10.1006/exnr.2002.7899
Experimental and therapeutic approaches to muscular dystrophies, , Current opinion in neurology, 2002, 10.1097/00019052-200210000-00007
RCAS1 is associated with ductal breast cancer progression, , Biochemical and biophysical research communications, 2002, 10.1016/S0006-291X(02)00401-1
The urokinase plasminogen activator: an interesting way to improve myoblast migration following their transplantation, , Experimental cell research, 2002, 10.1006/excr.2002.5642
Treatment with anti-CD154 antibody and donor-specific transfusion prevents acute rejection of myoblast transplantation, , Transplantation, 2002, 10.1097/00007890-200202150-00021
Combined immunosuppression of mycophenolate mofetil and FK506 for myoblast transplantation in mdx mice, , Transplantation, 2001, 10.1097/00007890-200107150-00010
Electrotransfer of naked DNA in the skeletal muscles of animal models of muscular dystrophies, , Gene therapy, 2001, 10.1038/sj.gt.3301484
Gene therapy: a strategy for the treatment of inherited muscle diseases?, , Current opinion in pharmacology, 2001, 10.1016/s1471-4892(01)00052-2
Intraarterial injection of muscle-derived CD34(+)Sca-1(+) stem cells restores dystrophin in mdx mice, , The Journal of cell biology, 2001, 10.1083/jcb.152.2.335
Intracellular delivery of a Tat-eGFP fusion protein into muscle cells, , Molecular therapy : the journal of the American Society of Gene Therapy, 2001, 10.1006/mthe.2001.0279
Scale-up of a myoblast culture process, , Journal of biotechnology, 2001, 10.1016/s0168-1656(01)00291-7
Transfection of large plasmids in primary human myoblasts, , Gene therapy, 2001, 10.1038/sj.gt.3301532
Transplantation of normal or genetically modified myoblasts for the treatment of hereditary or acquired diseases, , Journal de la Societe de biologie, 2001
Functional EGFP-dystrophin fusion proteins for gene therapy vector development, , Protein engineering, 2000, 10.1093/protein/13.9.611
Identification of homozygous and heterozygous dy2J mice by PCR, , Neuromuscular disorders : NMD, 2000, 10.1016/s0960-8966(99)00056-5
Immune Reaction Following Cell and Gene Therapy, , 2000
In vivo migration of transplanted myoblasts requires matrix metalloproteinase activity, , Experimental cell research, 2000, 10.1006/excr.2000.4962
Intramuscular migration of myoblasts transplanted after muscle pretreatment with metalloproteinases, , Cell transplantation, 2000, 10.1177/096368970000900410
Myoblast transplantation in whole muscle of nonhuman primates, , Journal of neuropathology and experimental neurology, 2000, 10.1093/jnen/59.3.197
Progress in myoblast transplantation: a potential treatment of dystrophies, , Microscopy research and technique, 2000, 10.1002/(SICI)1097-0029(20000201/15)48:3/43.0.CO;2-Z
Systemic production of human granulocyte colony-stimulating factor in nonhuman primates by transplantation of genetically modified myoblasts, , Human gene therapy, 2000, 10.1089/10430340050032384
Telomerase allows the immortalization of T antigen-positive DMD myoblasts: a new source of cells for gene transfer application, , Gene therapy, 2000, 10.1038/sj.gt.3301132
Transplantation of normal and DMD myoblasts expressing the telomerase gene in SCID mice, , Biochemical and biophysical research communications, 2000, 10.1006/bbrc.2000.2735
Use of normal and genetically modified myoblasts for the treatment of myopathies, , 2000
Increased myogenic potential and fusion of matrilysin-expressing myoblasts transplanted in mice, , Cell transplantation, 1999, 10.1177/096368979900800502
Male-specific competitive PCR for the quantification of transplanted cells in mice, , BioTechniques, 1999, 10.2144/99273bm05
Myoblast transplantations lead to the expression of the laminin alpha 2 chain in normal and dystrophic (dy/dy) mouse muscles, , Gene therapy, 1999, 10.1038/sj.gt.3300889
Successful myoblast transplantation in fibrotic muscles: no increased impairment by the connective tissue, , Transplantation, 1999, 10.1097/00007890-199906270-00018
Successful myoblast transplantation in primates depends on appropriate cell delivery and induction of regeneration in the host muscle, , Experimental neurology, 1999, 10.1006/exnr.1998.6973
Transplantation of human myoblasts in SCID mice as a potential muscular model for myotonic dystrophy, , Journal of neuropathology and experimental neurology, 1999, 10.1097/00005072-199909000-00003
Anti-inflammatory effect of transforming growth factor-beta1 in myoblast transplantation, , Transplantation, 1998, 10.1097/00007890-199803270-00005
Complement deposition and cell death after myoblast transplantation, , Cell transplantation, 1998, 10.1016/s0963-6897(98)00029-3
Evidence of mdx mouse skeletal muscle fragility in vivo by eccentric running exercise, , Muscle & nerve, 1998, 10.1002/(sici)1097-4598(199805)21:53.0.co;2-6
Expression of human dystrophin following the transplantation of genetically modified mdx myoblasts, , Gene therapy, 1998, 10.1038/sj.gt.3300753
Normal myoblast implantation in MDX mice prevents muscle damage by exercise, , Biochemical and biophysical research communications, 1998, 10.1006/bbrc.1998.9276
Prior culture with concanavalin A increases intramuscular migration of transplanted myoblast, , Muscle & nerve, 1998, 10.1002/(sici)1097-4598(199803)21:33.0.co;2-5
Successful transplantation of genetically corrected DMD myoblasts following ex vivo transduction with the dystrophin minigene, , Biochemical and biophysical research communications, 1998, 10.1006/bbrc.1998.8739
Transplantation of dermal fibroblasts expressing MyoD1 in mouse muscles, , Biochemical and biophysical research communications, 1998, 10.1006/bbrc.1998.8995
Transplantation of myoblasts from a transgenic mouse overexpressing dystrophin prduced only a relatively small increase of dystrophin-positive membrane, , Muscle & nerve, 1998, 10.1002/(sici)1097-4598(199801)21:13.0.co;2-3
Control of inflammatory damage by anti-LFA-1: increase success of myoblast transplantation, , Cell transplantation, 1997
Efficient myoblast transplantation in mice immunosuppressed with monoclonal antibodies and CTLA4 Ig, , Transplantation proceedings, 1997, 10.1016/s0041-1345(97)00166-8
Increase in the proliferative capacity of human myoblasts by using the T antigen under the vimentin promoter control, , Muscle & nerve, 1997, 10.1002/(sici)1097-4598(199704)20:43.0.co;2-b
Inflammatory damage following first-generation replication-defective adenovirus controlled by anti-LFA-1, , Journal of leukocyte biology, 1997, 10.1002/jlb.61.4.533
Meeting of the Cell Transplantation Society in Miami, , Cell transplantation, 1997
Muscle fibers of mdx mice are more vulnerable to exercise than those of normal mice, , Neuromuscular disorders : NMD, 1997, 10.1016/s0960-8966(97)00115-6
Myoblast transplantation: a brief review of the problems and of some solutions, , Basic and applied myology : BAM, 1997
Prevention by anti-LFA-1 of acute myoblast death following transplantation, , Journal of immunology (Baltimore, Md. : 1950), 1997
Role of non-major histocompatibility complex antigens in the rejection of transplanted myoblasts, , Transplantation, 1997, 10.1097/00007890-199703270-00016
Immunosuppression with monoclonal antibodies and CTLA4-Ig after myoblast transplantation in mice, , Transplantation, 1996, 10.1097/00007890-199610150-00015
Increased interferon-gamma mRNA expression following alloincompatible myoblast transplantation is inhibited by FK506, , Muscle & nerve, 1996, 10.1002/(SICI)1097-4598(199607)19:73.0.CO;2-B
Mechanism of increasing dystrophin-positive myofibers by myoblast transplantation: study using mdx/beta-galactosidase transgenic mice, , Acta neuropathologica, 1996, 10.1007/s004010050456
Myoblast transplantation in monkeys: control of immune response by FK506, , Journal of neuropathology and experimental neurology, 1996, 10.1097/00005072-199606000-00002
Partial laminin alpha2 chain restoration in alpha2 chain-deficient dy/dy mouse by primary muscle cell culture transplantation, , The Journal of cell biology, 1996, 10.1083/jcb.133.1.185
Prevention of immune reactions triggered by first-generation adenoviral vectors by monoclonal antibodies and CTLA4Ig, , Human gene therapy, 1996, 10.1089/hum.1996.7.12-1455
Successive injections in mdx mice of myoblasts grown with bFGF, , Neuromuscular disorders : NMD, 1996, 10.1016/0960-8966(96)00004-1
Cyclophosphamide immunosuppression does not permit successful myoblast allotransplantation in mouse, , Neuromuscular disorders : NMD, 1995, 10.1016/0960-8966(95)00011-b
FK506 immunosuppression to control the immune reactions triggered by first-generation adenovirus-mediated gene transfer, , Human gene therapy, 1995, 10.1089/hum.1995.6.11-1391
Increased granzyme B mRNA after alloincompatible myoblast transplantation, , Transplantation, 1995
Lymphocyte infiltration following allo- and xenomyoblast transplantation in mdx mice, , Muscle & nerve, 1995, 10.1002/mus.880180107
Myoblast allotransplantation in primates, , Muscle & nerve, 1995
Pretreatment of myoblast cultures with basic fibroblast growth factor increases the efficacy of their transplantation in mdx mice, , Muscle & nerve, 1995, 10.1002/mus.880180806
Quantification of normal dystrophin mRNA following myoblast transplantation in mdx mice, , Muscle & nerve, 1995, 10.1002/mus.880180909
Successful histocompatible myoblast transplantation in dystrophin-deficient mdx mouse despite the production of antibodies against dystrophin, , The Journal of cell biology, 1995, 10.1083/jcb.131.4.975
Successful myoblast allotransplantation in mdx mice using rapamycin, , Transplantation, 1995
Enzymatic activity and morphological differentiation in de novo innervated human muscle cultures, , European journal of histochemistry : EJH, 1994
High efficiency of muscle regeneration after human myoblast clone transplantation in SCID mice, , The Journal of clinical investigation, 1994, 10.1172/JCI117011
Human myoblast transplantation in immunodeficient and immunosuppressed mice: evidence of rejection, , Muscle & nerve, 1994, 10.1002/mus.880170214
Immunosuppression with FK 506 insures good success of myoblast transplantation in MDX mice, , Transplantation proceedings, 1994
Lymphocyte infiltration following allo- and xenomyoblast transplantation in mice, , Transplantation proceedings, 1994
Myoblast allotransplantation in mice: degree of success varies depending on the efficacy of various immunosuppressive treatments, , Transplantation proceedings, 1994
Polymerase chain reaction-based assay to assess the success of myoblast transplantation in mdx mice, , Transplantation proceedings, 1994
Utilization of myoblasts from transgenic mice to evaluate the efficacy of myoblast transplantation, , Muscle & nerve, 1994, 10.1002/mus.880170903
Very efficient myoblast allotransplantation in mice under FK506 immunosuppression, , Muscle & nerve, 1994, 10.1002/mus.880171210
Antibody formation after myoblast transplantation in Duchenne-dystrophic patients, donor HLA compatible, , Transplantation proceedings, 1993
Cytoplasmic restoration and persistence of glucose-6-phosphate dehydrogenase activity in stable hybrid myotubes, , European journal of histochemistry : EJH, 1993
Muscle glucose-6-phosphate dehydrogenase deficiency: restoration of enzymatic activity in hybrid myotubes, , Muscle & nerve, 1993, 10.1002/mus.880160604
Myoblast transplantation between monozygotic twin girl carriers of Duchenne muscular dystrophy, , Neuromuscular disorders : NMD, 1993, 10.1016/0960-8966(93)90121-y
Rapid selection of donor myoblast clones for muscular dystrophy therapy using cell surface expression of NCAM, , European journal of histochemistry : EJH, 1993
Results of a triple blind clinical study of myoblast transplantations without immunosuppressive treatment in young boys with Duchenne muscular dystrophy, , Cell transplantation, 1993, 10.1177/096368979300200203
Use of fluorescent latex microspheres (FLMs) to follow the fate of transplanted myoblasts, , The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1993, 10.1177/41.10.8245416
Utilization of an antibody specific for human dystrophin to follow myoblast transplantation in nude mice, , Cell transplantation, 1993, 10.1177/096368979300200204
A light and electron microscopic study of dystrophin localization at the mouse neuromuscular junction, , Synapse (New York, N.Y.), 1992, 10.1002/syn.890100202
Dystrophin-like immunoreactivity in monkey and human brain areas involved in learning and motor functions, , Neuroscience letters, 1992, 10.1016/0304-3940(92)90890-j
Evaluation of various gene transfection methods into human myoblast clones, , Transplantation proceedings, 1992
Human myoblast transplantation between immunohistocompatible donors and recipients produces immune reactions, , Transplantation proceedings, 1992
Human myoblast transplantation: preliminary results of 4 cases, , Muscle & nerve, 1992, 10.1002/mus.880150504
Immune reactions after myoblast transplantation in mouse muscles, , Transplantation proceedings, 1992
Localization of dystrophin in the Purkinje cells of normal mice, , Neuroscience letters, 1992, 10.1016/0304-3940(92)90309-u
Mosaic expression of dystrophin in the cerebellum of heterozygote dystrophic (mdx) mice, , Neuromuscular disorders : NMD, 1992, 10.1016/s0960-8966(06)80002-7
Myotubes can be formed within implanted adipose tissue, , Transplantation proceedings, 1992
A monoclonal antibody to conotoxin reveals the distribution of a subset of calcium channels in the rat cerebellar cortex, , Brain research. Molecular brain research, 1991, 10.1016/0169-328x(91)90004-h
A new technique to identify hybrid myotubes in vitro without culture fixation, , The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1991, 10.1177/39.1.1701185
Approche Thérapeutique de la myopathie de Duchenne par transplantation de myoblastes, , Medecine sciences : M/S, 1991
Cytomegalovirus and myoblast transplantation, , Lancet (London, England), 1991, 10.1016/0140-6736(91)93090-v
Dystrophin expression in myotubes formed by the fusion of normal and dystrophic myoblasts, , Muscle & nerve, 1991, 10.1002/mus.880140213
Expression of major histocompatibility complex antigens on human myoblasts, , Transplantation proceedings, 1991
Human myoblast transplantation: a simple assay for tumorigenicity, , Neuromuscular disorders : NMD, 1991, 10.1016/0960-8966(91)90120-h
In vitro bromodeoxyuridine labeling of nuclei: application to myotube hybridization, , The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1991, 10.1177/39.10.1940314
Is dystrophin present in the nerve terminal at the neuromuscular junction? An immunohistochemical study of the heterozygote dystrophic (mdx) mouse, , Synapse (New York, N.Y.), 1991, 10.1002/syn.890070207
Myoblast transplantation produced dystrophin-positive muscle fibres in a 16-year-old patient with Duchenne muscular dystrophy, , Clinical science (London, England : 1979), 1991, 10.1042/cs0810287
Non-uniform responses to Ca2+ along the frog neuromuscular junction: effects on the probability of spontaneous and evoked transmitter release, , Neuroscience, 1991, 10.1016/0306-4522(91)90142-b
Postsynaptic structure may account for variations in miniature endplate current shapes along frog neuromuscular junctions, , Synapse (New York, N.Y.), 1990, 10.1002/syn.890050402
Frequency and amplitude gradients of spontaneous release along the length of the frog neuromuscular junction, , Synapse (New York, N.Y.), 1989, 10.1002/syn.890030402
Proximodistal gradients of the postjunctional folds at the frog neuromuscular junction: a scanning electron microscopic study, , Neuroscience, 1989, 10.1016/0306-4522(89)90271-6
Gaba and benzodiazepines in invertebrate species, , 1988
Reduction of postjunctional fold density and depth in dystrophic mice, , Synapse (New York, N.Y.), 1988, 10.1002/syn.890020206
Scanning electron microscopic study of the neuromuscular junction of dystrophic mice, , Experimental neurology, 1988, 10.1016/0014-4886(88)90200-2
Incorporation of vesicular antigens into the presynaptic membrane during exocytosis at the frog neuromuscular junction: a light and electron microscopy immunochemical study, , Neuroscience, 1987, 10.1016/0306-4522(87)90147-3
Interrelation between MEPP amplitude and MEPP frequency in different regions along the frog neuromuscular junction, , Brain research, 1987, 10.1016/0006-8993(87)90404-5
Non-uniform distribution of miniature endplate potential amplitudes along the length of the frog neuromuscular junction, , Neuroscience letters, 1987, 10.1016/0304-3940(87)90147-9
Non-uniform release at the frog neuromuscular junction: evidence of morphological and physiological plasticity, , Brain research, 1987, 10.1016/0165-0173(87)90019-1
Repeated stimulation of the dystrophic mouse neuromuscular junctions, , Muscle & nerve, 1987, 10.1002/mus.880100405
Fast turnover of clear vesicle membrane in frog sympathetic ganglion, , Neuroscience, 1986, 10.1016/0306-4522(86)90093-x
Non monotonic morphometric changes produced at mouse neuromuscular junctions following in vivo stimulation at various frequencies, , Experimental brain research, 1986, 10.1007/BF00237590
A monoclonal antibody to beta-tubulin distinguishes a subset of neurons and axons in the chick ciliary ganglion, , Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire, 1985, 10.1139/o85-065
Miniature endplate potential amplitudes corrected for spatial decay are not normally distributed, , Brain research, 1985, 10.1016/0006-8993(85)91339-3
Distribution of spontaneous release along the frog neuromuscular junction, , Neuroscience letters, 1984, 10.1016/0304-3940(84)90559-7
Increased number per area of peptidergic and cholinergic vesicles in synapses of the chick ciliary ganglion following 10 Hz in vivo stimulation, , Neuroscience letters, 1983, 10.1016/0304-3940(83)90542-6
Is the MEPP due to the release of one vesicle or to the simultaneous release of several vesicles at one active zone?, , Brain research, 1983, 10.1016/0165-0173(83)90009-7
Labelling of an intermediate saccule of the Golgi apparatus and of parts of the endoplasmic reticulum by a lectin (soybean agglutinin) in the chick ciliary ganglion, , Neuroscience letters, 1983, 10.1016/0304-3940(83)90538-4
Boutons originating from the same axon do not participate equally in synaptic transmission, , Neuroscience letters, 1982, 10.1016/0304-3940(82)90342-1
Heterogeneous labeling of mitochondrial membrane, endoplasmic reticulum, neurofilaments and synaptic vesicles with a lectin (DBA-peroxidase), , Neuroscience letters, 1982, 10.1016/0304-3940(82)90003-9
Modulation of synapse RC1-R15 of Aplysia californica by fiber(s) of the right connective, , Canadian journal of physiology and pharmacology, 1982, 10.1139/y82-094
Baclofen modifies via the release of monoamines the synaptic depression, frequency facilitation, and posttetanic potentiation observed at an identified cholinergic synapse of Aplysia californica, , Canadian journal of physiology and pharmacology, 1981, 10.1139/y81-039
In vivo stimulation of a cholinergic synapse of the chick ciliary ganglion induces a reduction in the number of dense core vesicles, , Neuroscience letters, 1981, 10.1016/0304-3940(81)90176-2
Morphological changes in presynaptic terminals of the chick ciliary ganglion after stimulation in vivo. A stereological study showing a net loss of total membrane, , Experimental brain research, 1981, 10.1007/BF00238388
Benzodiazepines modify synaptic depression, frequency facilitation and PTP an identified cholinergic synapse of Aplysia, , Life sciences, 1980, 10.1016/0024-3205(80)90130-7
The effects of hemicholinium-3 on synaptic depression, facilitation, and post-tetanic potentiation at an identified synapse of Aplysia californica, , Canadian journal of physiology and pharmacology, 1980, 10.1139/y80-064
An electron microscope study of synaptic contacts in the abdominal ganglion of Aplysia californica, , The Journal of comparative neurology, 1979, 10.1002/cne.901880303
Synaptic contacts on glial cells in the abdominal ganglion of Aplysia californica, , The Journal of comparative neurology, 1979, 10.1002/cne.901880304
Presynaptic modulating effects of GABA on depression, facilitation, and posttetanic potentiation of a cholinergic synapse in Aplysia californica, , Canadian journal of physiology and pharmacology, 1977, 10.1139/y77-174
Dopamine, serotonin and related compounds: presynaptic effects on synaptic depression, frequency facilitation, and post-tetanic potentiation at a synapse in Aplysia californica, , Brain research, 1976, 10.1016/0006-8993(76)90380-2
Frequency facilitation and post-tetanic potentiation of a unitary synaptic potential in Aplysia californica are limited by different processes, , Brain research, 1976, 10.1016/0006-8993(76)90377-2
Heterosynaptic inhibition modifies the presynaptic plasticities of the transmission process at the synapse in Aplysia californica, , Brain research, 1976, 10.1016/0006-8993(76)90381-4
Resting and stimulated values of model parameters governing transmitter release at a synapse in Aplysia californica, , Brain research, 1976, 10.1016/0006-8993(76)90378-4
Synaptic depression at a synapse in Aplysia californica: analysis in terms of a material flow model of neurotransmitter, , Brain research, 1976, 10.1016/0006-8993(76)90379-6
Cholinergic agents affect two receptors that modulate transmitter release at a central synapse in Aplsia californica, , Brain research, 1975, 10.1016/0006-8993(75)90657-5
Marked prolongation of post-tetanic potentiation at a transition temperature in its adaption, , Nature, 1975, 10.1038/258623a0
Cerebroside may be falsely identified as a soluble 'brain specific protein', , Journal of neurochemistry, 1974, 10.1111/j.1471-4159.1974.tb04360.x
Depression and frequency facilitation at a synapse in Aplysia californica: evidence for regulation by availability of transmitter, , Brain research, 1974, 10.1016/0006-8993(74)90459-4
Morphine and related compounds: evidence that they decrease available neurotransmitter in Aplysia californica, , Brain research, 1974, 10.1016/0006-8993(74)90481-8
...
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Contribution à l'enseignement aux cycles supérieurs
Étudiant(e)s dirigé(e)s*
Depuis 2009
Gabriel Lamothe - Maitrîse avec mémoire - En cours
Yaovi Sylvestre Ahou - Doctorat - En cours
Annabelle Fortin-Archambault - Maitrîse avec mémoire - En cours
Bo Song - Doctorat - En cours
Solivan Boily - Maitrîse avec mémoire - En cours
Camille Bouchard - Maitrîse avec mémoire - En cours
Michael Ben Said - Doctorat - En cours
Yaoyao Lu - Doctorat - En cours
Seyed Mohammadreza Mirinezhad - Post-doctorat - En cours
Pouiré Yameogo - Doctorat - En cours
Kelly Godbout - Maitrîse avec mémoire - En cours
Cedric Happi Mbakam - Doctorat - En cours
Sriniasa Rao Nagubothu - Doctorat - En cours
Amina Dahmani - Doctorat - En cours
Maheswaran Kesavan - Doctorat - En cours
Nicolas B. Huot - Doctorat - En cours
Guillaume Tremblay - Maitrîse avec mémoire - En cours
Racha Metlej - Maitrîse avec mémoire - 2012/05
Jean-Paul Iyombe - Maitrîse avec mémoire - 2013/09
Laetitia Mavinga - Maitrîse avec mémoire - 2013/09
Chantale Maltais - Maitrîse avec mémoire - 2014/01
Ken Bisabu Kelu - Maitrîse avec mémoire - 2015/09
Amina Chikh - Maitrîse avec mémoire - 2015/09
William-Édouard Gravel - Maitrîse avec mémoire - 2016/01
Arnaud Perrin - Maitrîse avec mémoire - 2016/09
Daniel Agudelo - Maitrîse avec mémoire - 2016/09
Khadija Cherif - Maitrîse avec mémoire - 2017/01
Antoine Guyon - Doctorat - 2021/01
Malek Aloui - Maitrîse avec mémoire - 2021/09
Solange Gni-Fiene Yanyabe - Maitrîse avec mémoire - 2022/01
Encadrement d'étudiant(e)s pour les programmes suivants :
*Les supervisions d’étudiant(e)s de 1er cycle en
stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées
ultérieurement.
Vice-décanat à la recherche et aux études supérieures Pavillon Ferdinand-Vandry Université Laval 1050, avenue de la Médecine, local 4645 Québec (Québec) G1V 0A6 Canada
Catherine Comtois Agente de gestion des études etudes.sup2@fmed.ulaval.ca Biostatistique Épidémiologie Évaluation économique des technologies de la santé Santé publique
Marianne Rivest et Claudia Gonzalez Agentes de gestion des études etudes.sup1@fmed.ulaval.ca Biologie cellulaire et moléculaire Génomique fonctionnelle Médecine moléculaire Microbiologie-immunologie Neurosciences
Isabelle Tremblay Agente de gestion des études etudes.sup3@fmed.ulaval.ca Pédagogie universitaire en sciences de la santé Sciences cliniques et biomédicales Sciences de la réadaptation Prévention et gestion de la santé et de la sécurité au travail