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Jacques Corbeil
Professeur titulaire

Contribution à la recherche
Thématiques de recherche de la Faculté de médecine
- Bioinformatique / données massives (big data)
- Immunologie-infectiologie
- Oncologie
Projets de recherche en cours
- Identification of innate immune pathways as targets for immunomodulatory therapy in herpes simplex virus encephalitis - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2023-10-01 au 2028-09-30
- PandemicStop-AI: for an accelerated response to pandemics - Fondation Canadienne pour l'innovation (La) - Fonds d'infrastructure de recherche en sciences biologiques (FIRSB), Université de Montréal, co-chercheur - 2024-03-01 au 2028-03-31
- PandemicStop-AI: for an accelerated response to pandemics - Secrétariat des programmes interorganismes à l’intention des établissements - Fonds de recherche biomédical du Canada (FRBC), Université de Montréal, co-chercheur - 2024-03-01 au 2028-03-31
- National Primate Center for Pandemic Preparedness (NPCPP) - Fondation Canadienne pour l'innovation (La), Ministère de l'Économie et de l'Innovation et de l'énergie, Ministère de l'Enseignement supérieur - Fonds d'infrastructure de recherche en sciences biologiques (FIRSB), co-chercheur - 2024-03-01 au 2028-03-31
- Unravelling the impact of diet on cardiovascular health in heterozygous familial hypercholesterolemia: a metabolomic approach - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2021-10-01 au 2025-09-30
- Development of AI algorithms to support oncology drug development - MITACS Inc. - Accélération Québec (MITACS et gouvernement provincial), chercheur principal - 2025-02-03 au 2025-08-02
Financements des 2 dernières années
- Soutien séjour France (Sorbonne Université) - 2 au 10 février 2025 - Université Laval - Fonds internes - Programme d'appui aux initiatives internationales, chercheur principal - 2025-01-16 au 2025-04-30
- Development of an advanced multiplexed lab-on-a-chip system for highthroughput screening using organ-on-a-chip technology to support Al drug discovery - Secrétariat des programmes interorganismes à l’intention des établissements - Fonds d'excellence en recherche Apogée Canada, Université de Montréal, co-chercheur - 2024-03-01 au 2025-02-28
- Extreme zooming on intestinal permeability and the western-style diet: Unravelling the role of dietary antigens on the prevalence of cardiometabolic and mental health diseases in the North - Secrétariat des programmes interorganismes à l’intention des établissements - Sentinelle Nord - Deuxième appel à projets majeurs, co-chercheur - 2020-11-01 au 2024-12-31
- Chaire de recherche du Canada en Medical genomics - Instituts de recherche en santé du Canada - Chaires de recherche du Canada - Fonctionnement, chercheur principal - 2018-01-01 au 2024-12-31
- Ecogenomics of mining areas for sustainable Canadian North (GENOSCAN) - Secrétariat des programmes interorganismes à l’intention des établissements - Sentinelle Nord - Deuxième appel à projets majeurs, co-chercheur - 2020-11-01 au 2024-12-31
- Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.3 - Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
- L'empreinte métabolomique plasmatique des produits laitiers: un reflet de leur consommation et une fenêtre sur leurs effets cardiométaboliques - Les producteurs laitiers du Canada - Subvention à la recherche en nutrition, co-chercheur - 2022-10-01 au 2024-09-30
- Développement d’algorithmes d’IA pour soutenir le développement de médicaments oncologiques - MITACS Inc. - Accélération Québec (MITACS et gouvernement provincial), chercheur principal - 2024-04-01 au 2024-08-31
- Exploration multi-omique des biopsies liquides pour dépister les porteurs de bactéries pathogènes et leurs résistances - Université Laval - Fonds internes - BDR - Contributions, chercheur principal - 2023-04-24 au 2024-04-23
- Rôle des habitudes de vie sur le microbiote et la réponse clinique à l’immunothérapie en cancer de la vessie - Fonds de recherche du Québec - Santé - Projet subsidiaire - Nouveaux Centres et Instituts de recherche - Subventions régulières (pour fins de gestion au VRRCI), co-chercheur - 2023-04-20 au 2024-03-31
- Observatoire international sur les impacts sociétaux de l'intelligence artificielle et du numérique - Fonds de recherche du Québec - Société et culture, Université Laval - Fonds internes - Appel à propositions : création d’un Observatoire international sur les impacts sociétaux de l’intelligence artificielle et du numérique, co-chercheur - 2018-04-01 au 2024-03-31
- Antimicrobial resistance genes in bioaerosols in Canadian arctic, rural, and urban environments: sources, profiles, transport and fate - Conseil de recherches en sciences naturelles et génie Canada - Frontières de la découverte : Résistance aux antimicrobiens dans l'environnement, co-chercheur - 2019-12-01 au 2023-11-30
- Validation de la mesure d’expression génique unicellulaire à partir d’un échantillon de tissu hépatique chez des sujets avec une suspicion clinique de stéatose hépatique non-alcoolique. - Fonds de recherche du Québec - Santé, co-chercheur - 2022-08-24 au 2023-08-23
- Validation des marqueurs cellulaires ChromaLive sur modèles d'organopuces - MITACS Inc. - Accélération Québec (MITACS et gouvernement provincial), chercheur principal - 2022-12-12 au 2023-08-23
- UVILUQ: l'utilisation des biopsie liquides pour le monitoring de l'état de santé des écosystèmes marins côtiers - Secrétariat des programmes interorganismes à l’intention des établissements - Fonds d'excellence en recherche Apogée Canada, co-chercheur - 2020-07-01 au 2023-06-30
- Déterminer la qualité de la polypharmacie chez les aînés : une approche basée sur l’intelligence artificielle - Conseil de recherches en sciences naturelles et génie Canada, Instituts de recherche en santé du Canada - Subvention de fonctionnement : Projets de recherche concertée sur la santé (avec le CRSNG), co-chercheur - 2020-04-01 au 2023-03-31
- Prédire l'évolution de l'hépatite C par la fédération de données et l'intelligence artificielle : enjeux éthiques, juridiques, sociaux et de vie privée - Conseil de recherches en sciences naturelles et génie Canada, Instituts de recherche en santé du Canada, Conseil de recherches en sciences humaines du Canada - Subvention Projet, co-chercheur - 2019-04-01 au 2022-03-31
- Deciphering breast cancer HER2-negativity with regard to HER2-targeted therapy - Instituts de recherche en santé du Canada - Volet Projet: Concours pilotes, co-chercheur - 2016-07-01 au 2021-06-30
Publications
- Inhibition of ceramide-induced apoptosis by Bcl-2., Green DR, Reed JC, Kolesnick RN, Corbeil J, Miyashita T, McGahon AJ, Takayama S, Martin SJ, Cell death and differentiation, 1995
- Turncoat antibodies unmasked in a model of autoimmune demyelination: from biology to therapy, Vallières L, Marignier R, Flanagan EP, Corbeil J, Dominguez JM, Park A, Jaworski J, Zhou Q, Béland L, Bourhoven L, Zhang Y, Morin F, Taghipour-Mirakmahaleh R, 2024, 10.1101/2024.12.03.623846
- Nasopharyngeal carriage of individual Streptococcus pneumoniae serotypes during pediatric radiologically confirmed community acquired pneumonia following PCV7 introduction in Switzerland., Gervaix A, Galetto-Lacour A, Manzano S, Lacroix L, Alcoba G, Bouazza N, Maspoli V, Corbeil J, Raymond F, Robitaille L, Tabin R, Gehri M, Keitel K, Chappuy H, BMC infectious diseases, 2013, 10.1186/1471-2334-13-357
- Microarray truths and consequences., Corbeil J, Woelk CH, Sásik R, Journal of molecular endocrinology, 2004, 10.1677/jme.0.0330001
- Optimization & Characterization of Interdigitated Electrodes for Microbial Growth Monitoring., Gosselin B, Corbeil J, Messaddeq Y, Bl-George P, Gagnon-Turcotte G, Sarati Das P, Hosseini SN, Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2021, 10.1109/embc46164.2021.9630056
- Culture and properties of cells derived from Kaposi sarcoma., Penny R, Cooper DA, Vasak E, Evans LA, Corbeil J, Journal of immunology (Baltimore, Md. : 1950), 1991
- The next generation of automated microarray platforms for a multiplexed CYP2D6 assay, Corbeil, J., Hardiman, G., Kureshy, F., Mahant, V., Fu, Y.-K.K., Kim, P., Biochips as Pathways to Drug Discovery, 2006
- Building an HIV data mashup using Bio2RDF., Corbeil J, Belleau F, Dumontier M, Nolin MA, Briefings in bioinformatics, 2011, 10.1093/bib/bbr003
- Draft Genome Sequence of Romboutsia maritimum sp. nov. Strain CCRI-22766T, Isolated from Coastal Estuarine Mud., Bergeron MG, Omar RF, Broda D, Brightwell G, Corbeil J, Brodeur S, Raymond F, Boissinot M, Bérubé È, Boudreau DK, Maheux AF, Genome announcements, 2017, 10.1128/genomeA.01044-17
- Cutting edge: a novel viral TNF receptor superfamily member in virulent strains of human cytomegalovirus., Ware CF, Tschopp J, Schneider P, Rooney I, Corbeil J, Lurain NS, Butrovich KD, Benedict CA, Journal of immunology (Baltimore, Md. : 1950), 1999
- Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X., Morelli X, Collette Y, Arold ST, Huang M, Corbeil J, Zimmermann P, Madore E, Perez J, Parrot I, Coursindel T, Restouin A, Lugari A, Opi S, Shi X, The Biochemical journal, 2010, 10.1042/bj20100314
- Differential expression profiles of apoptosis-affecting genes in HIV-infected cell lines and patient T cells., Theofilopoulos AN, Corbeil J, Sabzevari H, Scheuring UJ, AIDS (London, England), 1999, 10.1097/00002030-199902040-00004
- Evolution of oseltamivir resistance mutations in Influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice., Boivin G, Corbeil J, Hamelin MÈ, Baz M, Carbonneau J, Plante PL, Abed Y, Pizzorno A, Antimicrobial agents and chemotherapy, 2014, 10.1128/AAC.02956-14
- Learning a peptide-protein binding affinity predictor with kernel ridge regression., Corbeil J, Drouin A, Laviolette F, Marchand M, Giguère S, BMC bioinformatics, 2013, 10.1186/1471-2105-14-82
- A new serotyping method of S. pneumoniae using an automated microarray-based assay., , International Conference on Prevention & Infection Control (ICPIC 2011), 2011, 10.1186/1753-6561-5-S6-O28
- Phenotypic and Genetic Characterization of the Cheese Ripening Yeast Geotrichum candidum, Labrie, S., Frenette, M., Dugat-Bony, E., Corbeil, J., Plante, P.-L., Lessard, M.-H., Vignola, S., Perkins, V., Frontiers in Microbiology, 2020, 10.3389/fmicb.2020.00737
- Enhanced antiproliferative effects of alkoxyalkyl esters of cidofovir in human cervical cancer cells in vitro., Corbeil J, Beadle JR, Trahan J, Rought S, Aldern KA, Hostetler KY, Molecular cancer therapeutics, 2006, 10.1158/1535-7163.mct-05-0200
- Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease., Arsenault BJ, Mathieu P, Mitchell PL, Couture C, Manikpurage HD, Gagnon E, Bourgault J, Abner E, Ghodsian N, Brière F, Taba N, Maltais-Payette I, Gobeil É, Metabolites, 2022, 10.3390/metabo12050440
- Complete Genome Sequences of Klebsiella michiganensis and Citrobacter farmeri, KPC-2-Producers Serially Isolated from a Single Patient. , Roy PH, Bergeron MG, Corbeil J, Boissinot M, Dewar K, D'Iorio M, Bérubé È, Déraspe M, Abed JY, Antibiotics (Basel, Switzerland), 2021, 10.3390/antibiotics10111408
- Role of CD95-activated caspase-1 processing of IL-1beta in TCR-mediated proliferation of HIV-infected CD4(+) T cells., Estaquier J, Ameisen JC, Green DR, Pinon G, Moutouh-de Parseval L, Lelièvre JD, Corbeil J, Petit F, European journal of immunology, 2001, 10.1002/1521-4141(200112)31:12<3513::aid-immu3513>3.0.co;2-j
- Antiproliferative effects of enediynes on AIDS-derived Kaposi's sarcoma cells., Looney DJ, Nicolaou KC, Wrasidlo W, Richman DD, Corbeil J, Cancer research, 1994
- The EcoChip: A Wireless Multi-Sensor Platform for Comprehensive Environmental Monitoring, Gosselin, B., Messaddeq, Y., Corbeil, J., Allard, M., Moineau, S., Raymond, F., Tremblay, D.M., Morency, S., Faucher, F., Bharucha, E., Lehoux, F., Sylvain, M., Proceedings - IEEE International Symposium on Circuits and Systems, 2018, 10.1109/ISCAS.2018.8351654
- Gene expression modulation and the molecular mechanisms involved in Nelfinavir resistance in Leishmania donovani axenic amastigotes., Tremblay MJ, Ouellette M, Corbeil J, Jalaguier P, Ritt JF, Raymond F, Lodge R, Kumar P, Molecular microbiology, 2013, 10.1111/mmi.12298
- Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays., Ouellette M, Légaré D, Bergeron MG, Corbeil J, Papadopoulou B, Messier N, Richard D, Briand G, Peytavi R, El Fadili A, Marquis N, Brochu C, Trudel N, Guimond C, Nucleic acids research, 2003, 10.1093/nar/gkg806
- Methamphetamine stimulates interferon inducible genes in HIV infected brain., HNRC Group, Masliah E, Grant I, Fox H, Sasik R, Corbeil J, Roberts E, Salaria S, Everall I, Journal of neuroimmunology, 2005, 10.1016/j.jneuroim.2005.09.009
- A general framework for analyzing data from two short time-series microarray experiments., Corbeil J, Shah M, IEEE/ACM transactions on computational biology and bioinformatics, 2011, 10.1109/tcbb.2009.51
- Flexible protein database based on amino acid k-mers., Corbeil J, Roy PH, Laviolette F, Boisvert S, Déraspe M, Scientific reports, 2022, 10.1038/s41598-022-12843-9
- Productive infection and subsequent interaction of CD4-gp120 at the cellular membrane is required for HIV-induced apoptosis of CD4+ T cells, Richman, D.D., Corbeil, J., Journal of General Virology, 1995, 10.1099/0022-1317-76-3-681
- mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome., Shaw RJ, Vera DR, Wu CL, Leblanc M, Wu S, Corbeil J, Vasquez DS, Shackelford DB, Proceedings of the National Academy of Sciences of the United States of America, 2009, 10.1073/pnas.0900465106
- Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species., Korf IF, Corbeil J, Chou WC, Chitsaz H, Chikhi R, Chapuis G, Chapman JA, Boisvert S, Birol I, Bechner M, Baranay P, Alexandrov A, Fass JN, Bradnam KR, GigaScience, 2013, 10.1186/2047-217X-2-10
- Learning self-supervised molecular representations for drug-drug interaction prediction., Corbeil J, Rousseau E, Dallaire P, Kpanou R, BMC bioinformatics, 2024, 10.1186/s12859-024-05643-7
- Sand DNAa genetic library of life at the water's edge, , Marine Ecology Progress Series, 2005, 10.3354/meps301009
- Whole-genome comparative RNA expression profiling of axenic and intracellular amastigote forms of Leishmania infantum., Papadopoulou B, Ouellette M, Corbeil J, Raymond F, Rochette A, Molecular and biochemical parasitology, 2009, 10.1016/j.molbiopara.2008.12.012
- MOT: a Multi-Omics Transformer for multiclass classification tumour types predictions, Corbeil J, Laviolette F, Tossou P, Osseni MA, 2022, 10.21203/rs.3.rs-1348696/v2
- The density of coreceptors at the surface of CD4+ T cells contributes to the extent of human immunodeficiency virus type 1 viral replication-mediated T cell death., Estaquier J, Gervaix A, Corbeil J, Ameisen JC, Arnoult D, Mammano F, Perrin L, Petit F, Lelièvre JD, AIDS research and human retroviruses, 2004, 10.1089/aid.2004.20.1230
- Predictive computational phenotyping and biomarker discovery using reference-free genome comparisons., Corbeil J, Laviolette F, Bourgault AM, Loo VG, Tyers M, Marchand M, Déraspe M, Giguère S, Drouin A, BMC genomics, 2016, 10.1186/s12864-016-2889-6
- Human Analysts at Superhuman Scales: What Has Friendly Software To Do?, Corbeil J, Laviolette F, Long B, Sosa CP, Behling S, Kandel M, Xia F, Boisvert S, Godzaridis É, Big data, 2013, 10.1089/big.2013.0031
- Ray: simultaneous assembly of reads from a mix of high-throughput sequencing technologies., Corbeil J, Laviolette F, Boisvert S, Journal of computational biology : a journal of computational molecular cell biology, 2010, 10.1089/cmb.2009.0238
- Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy., Ouellette M, Papadopoulou B, Olivier M, Tremblay MJ, Corbeil J, Rigault P, Boisvert S, Ouameur AA, Raymond F, Légaré D, Ubeda JM, Genome biology, 2008, 10.1186/gb-2008-9-7-r115
- Effects of antiretroviral drugs on human immunodeficiency virus type 1-induced CD4(+) T-cell death., Corbeil J, Ameisen JC, Richman DD, Moutouh-De Parseval L, Brunner T, Petit F, Lelièvre JD, Estaquier J, Journal of virology, 2002, 10.1128/JVI.76.12.5966-5973.2002
- HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism., Leoni LM, Corbeil J, Carson DA, Richman DD, Kroemer G, Susin SA, Zaunders JJ, Rought S, Sheeter D, Genini D, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, 10.1096/fj.00-0336fje
- Gene expression analysis of osteoblastic cells contacted by orthopedic implant particles., Corbeil J, Du P, Takei H, Genini D, Leoni L, Pioletti DP, Journal of biomedical materials research, 2002, 10.1002/jbm.10218
- Genomic diversity and CRISPR-Cas systems in the cyanobacterium Nostoc in the High Arctic., Vincent WF, Corbeil J, Culley AI, Lovejoy C, Francovic-Fontaine É, Déraspe M, Nguyen GQ, Mohit V, Moineau S, Dion MB, Raymond F, Jungblut AD, Environmental microbiology, 2021, 10.1111/1462-2920.15481
- Complete Genome Sequence of Escherichia coli Siphophage BRET., Moineau S, Aoussi S, Coulibaly DN, Soro BK, Koudou A, Corbeil J, Plante PL, Lemire N, Hutinet G, Tremblay DM, Addablah AA, Rousseau GM, Shao Y, Ngazoa-Kakou S, Microbiology resource announcements, 2019, 10.1128/MRA.01644-18
- Epitope mapping of the 2009 pandemic and the A/Brisbane/59/2007 seasonal (H1N1) influenza virus haemagglutinins using mAbs and escape mutants., Boivin G, Corbeil J, Abed Y, Retamal M, The Journal of general virology, 2014, 10.1099/vir.0.067819-0
- Genetic basis of hypersusceptibility to protease inhibitors and low replicative capacity of human immunodeficiency virus type 1 strains in primary infection., Little SJ, Hellmann NS, Corbeil J, Routy JP, Margolick JB, Conway B, Connick E, Collier AC, Markowitz M, Simon V, Daar ES, Good B, Frost SD, Leigh Brown AJ, Journal of virology, 2004, 10.1128/JVI.78.5.2242-2246.2004
- Single-cell transcriptomics of the ventral posterolateral nucleus-enriched thalamic regions from HSV-1-infected mice reveal a novel microglia/microglia-like transcriptional response., Boivin G, Corbeil J, Tremblay ME, Vallières L, Ibáñez FG, Lapeyre L, Bordeleau M, Uyar O, Dominguez JM, Journal of neuroinflammation, 2022, 10.1186/s12974-022-02437-7
- Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest, Spector, D.H., Richman, D.D., Corbeil, J., Clark, C., Fortunato, E.A., Ruchti, F., Jault, J.-M., Jault, F.M., Journal of Virology, 1995, 10.1128/jvi.69.11.6697-6704.1995
- Label-free detection of biomolecular interactions in real time with a nano-porous silicon-based detection method., Corbeil J, Latterich M, Proteome science, 2008, 10.1186/1477-5956-6-31
- Enhancement of HIV-1-induced syncytium formation in T cells by the tyrosyl kinase p56lck., Tremblay M, Corbeil J, Barbeau B, Briand G, Virology, 1997, 10.1006/viro.1997.8518
- Draft Genome Sequence of Criibacterium bergeronii gen. nov., sp. nov., Strain CCRI-22567T, Isolated from a Vaginal Sample from a Woman with Bacterial Vaginosis., Omar RF, Boissinot M, Roy PH, Corbeil J, Raymond F, Boudreau DK, Bérubé È, Maheux AF, Genome announcements, 2016, 10.1128/genomeA.00959-16
- Gln-tRNAGln synthesis in a dynamic transamidosome from Helicobacter pylori, where GluRS2 hydrolyzes excess Glu-tRNAGln., Lapointe J, Kern D, Hendrickson TL, Diss G, Lorber B, Madore E, Corbeil J, Fischer F, Huot JL, Nucleic acids research, 2011, 10.1093/nar/gkr619
- Timing and Predictors of Loss of Infectivity Among Healthcare Workers With Mild Primary and Recurrent COVID-19: A Prospective Observational Cohort Study., Longtin Y, De Serres G, Corbeil J, Savard P, Villeneuve J, Beaulac SN, Parkes L, Longtin J, Levade I, Carazo S, Fafard J, Roy T, Charest H, Dzieciolowska S, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024, 10.1093/cid/ciad535
- Draft Genome Sequence of a Sporulating and Motile Strain of Lachnotalea glycerini Isolated from Water in Québec City, Canada., Bergeron MG, Omar RF, Isabel S, Corbeil J, Brodeur S, Raymond F, Boissinot M, Bérubé È, Boudreau DK, Maheux AF, Genome announcements, 2017, 10.1128/genomeA.01059-17
- A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis., Boivin G, Corbeil J, Carbonneau J, Venable MC, Piret J, Plante PL, Uyar O, Scientific reports, 2021, 10.1038/s41598-021-98047-z
- Substitution of dietary monounsaturated fatty acids from olive oil for saturated fatty acids from lard increases low-density lipoprotein apolipoprotein B-100 fractional catabolic rate in subjects with dyslipidemia associated with insulin resistance: a randomized controlled trial., Couture P, Lamarche B, Schaefer EJ, Charest A, Lemelin V, Corbeil J, Drouin-Chartier JP, Rancourt-Bouchard M, Tremblay AJ, Brière F, Desjardins LC, The American journal of clinical nutrition, 2024, 10.1016/j.ajcnut.2024.03.015
- A new Microviridae phage isolated from a failed biotechnological process driven by Escherichia coli., Moineau S, Corbeil J, Plante PL, Tremblay DM, Dupuis MÈ, Labrie SJ, Applied and environmental microbiology, 2014, 10.1128/AEM.01365-14
- A new reporter cell line to monitor HIV infection and drug susceptibility in vitro., Corbeil J, Wong-Staal F, Richman DD, Leoni LM, West D, Gervaix A, Proceedings of the National Academy of Sciences of the United States of America, 1997, 10.1073/pnas.94.9.4653
- Communities of Phytoplankton Viruses across the Transition Zone of the St. Lawrence Estuary, Alexander Culley, Jacques Corbeil, Martyne Audet, Vani Mohit, Mary Thaler, Alice Lévesque, Frédéric Raymond, Myriam Labbé, Viruses, 2018, 10.3390/v10120672
- Phylogenomic insights into evolutionary trajectories of multidrug resistant S. pneumoniae CC271 over a period of 14 years in China., Feng J, Li Y, Corbeil J, Zhang J, Li C, Wei D, Zhang G, Coelho AC, Wang C, Wu Q, Cui L, Song Y, Zeng Y, Genome medicine, 2023, 10.1186/s13073-023-01200-8
- Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques., Zaunders J, Kelleher AD, Kent SJ, Cooper DA, Corbeil J, Suzuki K, Wilson K, Estaquier J, De Rose R, Alcantara S, Bailey M, Weatherall C, Xu Y, Journal of virology, 2013, 10.1128/JVI.02497-12
- Use of keyword hierarchies to interpret gene expression patterns., Corbeil J, Klacansky I, Gribskov M, Lynn Fink J, Welsh JB, Masys DR, Bioinformatics (Oxford, England), 2001, 10.1093/bioinformatics/17.4.319
- Virological importance of the protease-cleavage site in human immunodeficiency virus type 1 Nef is independent of both intravirion processing and CD4 down-regulation., Guatelli J, Corbeil J, Moutouh L, Craig H, Pandori M, Virology, 1998, 10.1006/viro.1998.9407
- Gut metagenome profile of the Nunavik Inuit youth is distinct from industrial and non-industrial counterparts., Rousseau E, Corbeil J, Ayotte P, Poliakova N, Muckle G, Bélanger RE, Bergeron MG, Boissinot M, Plante PL, Mehdaoui F, Godon T, Abed JY, Communications biology, 2022, 10.1038/s42003-022-04372-y
- Culture-enriched human gut microbiomes reveal core and accessory resistance genes., Corbeil J, Bergeron MG, Ouellette M, Roy PH, Huletsky A, Bérubé È, Kpanou SR, Plante PL, Déraspe M, Ouameur AA, Boissinot M, Raymond F, Microbiome, 2019, 10.1186/s40168-019-0669-7
- Productive HIV-1 infection of primary CD4+ T cells induces mitochondrial membrane permeabilization leading to a caspase-independent cell death., Estaquier J, Ameisen JC, Corbeil J, Schneider P, Hance AJ, Moutouh-de Parseval L, Lelièvre JD, Arnoult D, Petit F, The Journal of biological chemistry, 2001, 10.1074/jbc.m102671200
- Making linked data SPARQL with the InterMine biological data warehouse, Dumontier, M., Micklem, G., Yehudi, Y., Sullivan, J., Lyne, R., Karra, K., Heimbach, J., Corbeil, J., Contrino, S., Clark-Casey, J., Cherry, J.M., Chadwick, M., Butano, D., Binkley, G., Déraspe, M., CEUR Workshop Proceedings, 2016
- Metagenomic analysis of stress genes in microbial mat communities from Antarctica and the High Arctic., Corbeil J, Vincent WF, Jungblut AD, Lovejoy C, Varin T, Applied and environmental microbiology, 2011, 10.1128/AEM.06354-11
- Gene expression profiling and molecular characterization of antimony resistance in Leishmania amazonensis., Ouellette M, Frézard F, Melo MN, Corbeil J, Légaré D, Raymond F, Coelho AC, do Monte-Neto RL, PLoS neglected tropical diseases, 2011, 10.1371/journal.pntd.0001167
- HIV downregulates interferon-stimulated genes in primary macrophages., Woelk CH, Richman DD, Kornbluth RS, Corbeil J, Lozach J, Beliakova-Bethell N, Rought SE, Luong TQ, Du P, Wie SH, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2012, 10.1089/jir.2012.0052
- HIV-induced apoptosis requires the CD4 receptor cytoplasmic tail and is accelerated by interaction of CD4 with p56lck., Richman DD, Tremblay M, Corbeil J, The Journal of experimental medicine, 1996, 10.1084/jem.183.1.39
- Machine learning assisted design of highly active peptides for drug discovery., Corbeil J, Biron É, Liang X, Moineau S, Tremblay D, Marchand M, Laviolette F, Giguère S, PLoS computational biology, 2015, 10.1371/journal.pcbi.1004074
- Comparison of risk factors for human metapneumovirus and respiratory syncytial virus disease severity in young children., Boivin G, De Serres G, Frenette L, Caouette G, Corbeil J, Robitaille L, Raymond F, Ouakki M, Carbonneau J, Ouhoummane N, Hamelin MÈ, Papenburg J, The Journal of infectious diseases, 2012, 10.1093/infdis/jis333
- Global Mapping of the Macrophage-HIV-1 Transcriptome Reveals that Productive Infection Induces Remodeling of Host Cell DNA and Chromatin., Corbeil J, Tremblay MJ, Roy MA, Barat C, Lodge R, Raymond F, Ouellet M, Breton Y, Joly-Beauparlant C, Deshiere A, Scientific reports, 2017, 10.1038/s41598-017-05566-9
- Characterization of vancomycin-resistance vanD gene clusters in the human intestinal microbiota by metagenomics and culture-enriched metagenomics., Bergeron MG, Corbeil J, Boissinot M, Frenette J, Ouameur AA, Bérubé È, Raymond F, Boudreau DK, Huletsky A, Brochu E, JAC-antimicrobial resistance, 2023, 10.1093/jacamr/dlad026
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- The EcoChip 2: An Autonomous Sensor Platform for Multimodal Bio-environmental Monitoring of the Northern Habitat, Gosselin, B., Corbeil, J., Messaddeq, Y., Moineau, S., Tremblay, D., Bharucha, E., Hosseini, S.N., Bouzid, K., Ouazaa, K., Gagnon-Turcotte, G., Das, P.S., Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 2020, 10.1109/EMBC44109.2020.9176335
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- HIV/SIV infection primes monocytes and dendritic cells for apoptosis., Estaquier J, Elbim C, Zaunders J, Corbeil J, Hurtrel B, Cumont MC, Monceaux V, Campillo-Gimenez L, Laforge M, PLoS pathogens, 2011, 10.1371/journal.ppat.1002087
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- Nonpathogenesis of simian immunodeficiency virus infection is associated with reduced inflammation and recruitment of plasmacytoid dendritic cells to lymph nodes, not to lack of an interferon type I response, during the acute phase., Estaquier J, Elbim C, Corbeil J, Zaunders J, Hurtrel B, Lévy Y, Diop O, Monceaux V, Cumont MC, Brussel A, Fay M, Laforge M, Campillo-Gimenez L, Journal of virology, 2009, 10.1128/JVI.01496-09
- Draft Genome Sequence of Romboutsia weinsteinii sp. nov. Strain CCRI-19649T Isolated from Surface Water., Bergeron MG, Omar RF, Corbeil J, Raymond F, Cantin P, Boissinot M, Bérubé È, Boudreau DK, Maheux AF, Genome announcements, 2017, 10.1128/genomeA.00901-17
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- Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species., Corbeil J, Ouellette M, Papadopoulou B, Tremblay MJ, Olivier M, Stanke M, Isnard A, Légaré D, Ritt JF, Roy G, Boisvert S, Raymond F, Nucleic acids research, 2011, 10.1093/nar/gkr834
- The initial state of the human gut microbiome determines its reshaping by antibiotics., Corbeil J, Simard JL, Boudreau DK, Frenette J, Bérubé È, Giroux R, Plante PL, Leprohon P, Dridi B, Gingras H, Iqbal N, Déraspe M, Ouameur AA, Raymond F, The ISME journal, 2015, 10.1038/ismej.2015.148
- Symptomatology during previous SARS-CoV-2 infection and serostatus before vaccination influence the immunogenicity of BNT162b2 COVID-19 mRNA vaccine., Decaluwe H, Gilca V, Corbeil J, De Serres G, Cheng MP, Longtin Y, Savard P, McCormack D, Hamelin MÈ, Rabezanahary H, Carbonneau J, Adams K, Bourdin B, Nantel S, Frontiers in immunology, 2022, 10.3389/fimmu.2022.930252
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- Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins., Aroian RV, van der Goot FG, Corbeil J, Sasik R, Abrami L, Huffman DL, Proceedings of the National Academy of Sciences of the United States of America, 2004, 10.1073/pnas.0404073101
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- Molecular evolution of respiratory syncytial virus fusion gene, Canada, 2006-2010., Boivin G, De Serres G, Bergeron MG, Corbeil J, Paes BA, Déry P, Ohoumanne N, Bouhy X, Isabel S, Hamelin MÈ, Carbonneau J, Papenburg J, Emerging infectious diseases, 2012, 10.3201/eid1801.110515
- Comparison of Automated Microarray Detection with Real-Time PCR Assays for Detection of Respiratory Viruses in Specimens Obtained from Children., Corbeil J, Boivin G, De Serres G, Wu W, Boisvert S, Robitaille L, Boucher N, Carbonneau J, Raymond F, Journal of clinical microbiology, 2010, 10.1128/JCM.00255-10
- MHC-NP: predicting peptides naturally processed by the MHC., Laviolette F, Corbeil J, Marchand M, Lacoste A, Drouin A, Giguère S, Journal of immunological methods, 2013, 10.1016/j.jim.2013.10.003
- Targeted Proteomics of Human Metapneumovirus in Clinical Samples and Viral Cultures., Moseley MA, Corbeil J, Boivin G, Plante PL, Robitaille L, Gerhardt G, Foster MW, Analytical chemistry, 2015, 10.1021/acs.analchem.5b01544
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- Machine learning analysis identifies genes differentiating triple negative breast cancers, Durocher, F., Diorio, C., Lambert, J.-P., Corbeil, J., Laviolette, F., Déraspe, M., Ouellette, G., Agbo, L., Osseni, M.A., Kothari, C., Scientific Reports, 2020, 10.1038/s41598-020-67525-1
- Polyclonal proliferation and apoptosis of CCR5+ T lymphocytes during primary human immunodeficiency virus type 1 infection: regulation by interleukin (IL)-2, IL-15, and Bcl-2., Corbeil J, Little S, Estaquier J, Grey P, Smith DE, Cooper DA, Leoni L, Kelleher A, Genini D, Rought S, Reed JC, Kitada S, Moutouh-de Parseval L, Zaunders JJ, The Journal of infectious diseases, 2003, 10.1086/375030
- Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum., Ouellette M, Corbeil J, Hardiman G, Madore E, Raymond F, Légaré D, Leprohon P, Nucleic acids research, 2009, 10.1093/nar/gkn1069
- Associations between circulating amino acids and metabolic dysfunction-associated steatotic liver disease in individuals living with severe obesity., Tchernof A, Arsenault BJ, Corbeil J, Brière F, Couture C, Mitchell PL, Julien F, Marceau S, Biertho L, Gauthier MF, Bourgault J, Maltais-Payette I, Physiological reports, 2025, 10.14814/phy2.70171
- HIV-1 coreceptor usage prediction without multiple alignments: an application of string kernels., Corbeil J, Laviolette F, Marchand M, Boisvert S, Retrovirology, 2008, 10.1186/1742-4690-5-110
- Predicting Ion Mobility Collision Cross-Sections Using a Deep Neural Network: DeepCCS., Corbeil J, Marchand M, Laviolette F, Baker ES, McLean JA, May JC, Francovic-Fontaine É, Plante PL, Analytical chemistry, 2019, 10.1021/acs.analchem.8b05821
- Mass spectra alignment using virtual lock-masses., Laviolette F, Corbeil J, Marchand M, Diorio C, Durocher F, Richard D, Gagnon D, Drouin A, Plante PL, Brochu F, Scientific reports, 2019, 10.1038/s41598-019-44923-8
- Exploring polypharmacy with artificial intelligence: data analysis protocol., Simard M, Corbeil J, Savard AM, Laviolette F, Gagné C, Després P, Bureau A, Talbot D, Chiu Y, Bukhtiyarova O, Deziel PL, Durand A, Khoury R, Sirois C, BMC medical informatics and decision making, 2021, 10.1186/s12911-021-01583-x
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- Interferon gene expression following HIV type 1 infection of monocyte-derived macrophages., Corbeil J, Richman DD, Kornbluth RS, Sasik R, Lozach J, Rought SE, Royer CD, Du P, Plotkin CR, Ottones F, Woelk CH, AIDS research and human retroviruses, 2004, 10.1089/aid.2004.20.1210
- Partial recovery of microbiomes after antibiotic treatment., Corbeil J, Bergeron MG, Boissinot M, Déraspe M, Raymond F, Gut microbes, 2016, 10.1080/19490976.2016.1216747
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- Clostridium difficile: Investigating Transmission Patterns Between Symptomatic and Asymptomatic Patients Using Whole Genome Sequencing., Loo V, Toye B, Michaud S, Dascal A, Bourgault A, Wilcox M, Walker AS, Raymond F, Corbeil J, Eyre D, Kong LY, Open forum infectious diseases, 2017, 10.1093/ofid/ofx162.000
- Streamlining CRISPR spacer-based bacterial host predictions to decipher the viral dark matter., Moineau S, Corbeil J, Shah SA, Zufferey E, Plante PL, Dion MB, Nucleic acids research, 2021, 10.1093/nar/gkab133
- Genomic characterization of a large outbreak of Legionella pneumophila serogroup 1 strains in Quebec City, 2012., Tremblay C, Corbeil J, Faucher SP, Desbiens F, Goupil-Sormany I, Huot C, Raymond F, Charest H, Marchand G, Cantin P, Mendis N, Plante PL, Lévesque S, PloS one, 2014, 10.1371/journal.pone.0103852
- The transcription factor Egr1 regulates the HIF-1alpha gene during hypoxia., de Belle I, Corbeil J, Robitaille L, Sasik R, Fortin J, Sperandio S, Molecular carcinogenesis, 2009, 10.1002/mc.20454
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- Criibacterium bergeronii gen. nov., sp. nov., a new member of the family Peptostreptococcaceae, isolated from human clinical samples. , Omar RF, Roy PH, Domingo MC, Corbeil J, Raymond F, Guay ÉF, Ducrey É, Hashimi A, Bernard KA, Brodeur S, Bérubé È, Abed JY, Boudreau DK, Maheux AF, International journal of systematic and evolutionary microbiology, 2019, 10.1099/ijsem.0.004691
- The REinfection in COVID-19 Estimation of Risk (RECOVER) study: Reinfection and serology dynamics in a cohort of Canadian healthcare workers., Quach-Thanh C, Nantel S, Bourdin B, Adams K, Carbonneau J, Tadount F, Hamelin MÈ, Cheng MP, Savard P, Decaluwe H, McCormack D, Longtin Y, Boivin G, Racine É, Influenza and other respiratory viruses, 2022, 10.1111/irv.12997
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- The EcoChip: A Wireless Multi-Sensor Platform for Comprehensive Environmental Monitoring., Gosselin B, Messaddeq Y, Corbeil J, Allard M, Moineau S, Sarrazin D, Raymond F, Tremblay DM, Bharucha E, Faucher F, Morency S, Lehoux F, Sylvain M, IEEE transactions on biomedical circuits and systems, 2018, 10.1109/tbcas.2018.2878404
- On the robustness of generalization of drug-drug interaction models., Corbeil J, Laviolette F, Tossou P, Osseni MA, Kpanou R, BMC bioinformatics, 2021, 10.1186/s12859-021-04398-9
- Effect of micromechanical stimulations on osteoblasts: development of a device simulating the mechanical situation at the bone-implant interface., Wild E, Corbeil J, Rakotomanana LR, Müller J, Pioletti DP, Journal of biomechanics, 2003, 10.1016/s0021-9290(02)00301-9
- Clostridium difficile: Investigating Transmission Patterns Between Infected and Colonized Patients Using Whole Genome Sequencing., Loo VG, Dascal A, Bourgault AM, Schiller I, Dendukuri N, Frost E, Toye B, Michaud S, Crook DW, Wilcox MH, Walker AS, Raymond F, Corbeil J, Eyre DW, Kong LY, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 10.1093/cid/ciy457
- Surface CD4 expression modulated by a cellular factor induced by HIV type 1 infection., Corbeil J, Richman D, Rought S, Du P, Sheeter D, AIDS research and human retroviruses, 2003, 10.1089/088922203762688621
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- The density of coreceptors at the surface of CD4+ T cells contributes to the extent of human immunodeficiency virus type 1 viral replication-mediated T cell death, Estaquier, J., Gervaix, A., Corbeil, J., Ameisen, J.-C., Arnoult, D., Mammano, F., Perrin, L., Petit, F., Lelièvre, J.-D., AIDS Research and Human Retroviruses, 2004, 10.1089/0889222042545045
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- Intra-uterine growth restriction and the programming of left ventricular remodelling in female rats., Brochu M, Corbeil J, Comte B, Chorvatova A, Calvo E, Battista MC, The Journal of physiology, 2005, 10.1113/jphysiol.2004.078139
- Human viral pathogens are pervasive in wastewater treatment center aerosols., Duchaine C, Culley A, Corbeil J, Lavoie J, Dion-Dupont V, Veillette M, Brisebois E, Journal of environmental sciences (China), 2017, 10.1016/j.jes.2017.07.015
- Arctic microbial ecosystems and impacts of extreme warming during the International Polar Year, Mueller, D.R., Corbeil, J., Suttle, C.A., Laurion, I., Greer, C.W., Lovejoy, C., Whyte, L.G., Vincent, W.F., Polar Science, 2009, 10.1016/j.polar.2009.05.004
- Genome-wide stochastic adaptive DNA amplification at direct and inverted DNA repeats in the parasite Leishmania., Ouellette M, Corbeil J, Papadopoulou B, Leprohon P, Lapointe A, Roy G, Gingras H, Plourde M, Mukherjee A, Raymond F, Ubeda JM, PLoS biology, 2014, 10.1371/journal.pbio.1001868
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- Chipping Away at HIV Pathogenesis, , Pathogen Genomics, 2002, 10.1007/978-1-59259-172-5_2
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- Diminished somatostatin gene expression in individuals with HIV and major depressive disorder., HNRC (HIV Neurobehavioral Research Center), Masliah E, Grant I, Corbeil J, Young C, Atkinson JH, Salaria S, Everall IP, Neurology, 2006, 10.1212/01.wnl.0000244436.04036.a2
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- Large-scale analysis of circulating glutamate and adipose gene expression in relation to abdominal obesity., Tchernof A, Grundberg E, Brière F, Corbeil J, Simon MM, Vijay J, Maltais-Payette I, Amino acids, 2022, 10.1007/s00726-022-03181-1
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- Serratia marcescens SCH909 as reservoir and source of genetic elements related to wide dissemination of antimicrobial resistance mechanisms. , Centrón D, Roy PH, Corbeil J, Quiroga MP, Álvarez VE, Déraspe M, Gambino AS, FEMS microbiology letters, 2021, 10.1093/femsle/fnab086
- Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia., Tsuang MT, Liew CC, Han M, Khanlou N, Sásik R, Corbeil J, Kremen WS, Everall IP, Glatt SJ, Proceedings of the National Academy of Sciences of the United States of America, 2005, 10.1073/pnas.0507666102
- Improving the safety of Staphylococcus aureus polyvalent phages by their production on a Staphylococcus xylosus strain., Moineau S, St-Gelais D, Corbeil J, Labrie S, Katsarava R, Dumaresq J, Plante PL, Ben Abdallah N, El Haddad L, PloS one, 2014, 10.1371/journal.pone.0102600
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- The Ick protein tyrosine kinase is not involved in antibody-mediated CD4 (CDR3-loop) signal transduction that inhibits HIV-1 transcription, Devaux, C., Mesnard, J.-M., Robert-Hebmann, V., Corbeil, J., Coudronnière, N., European Journal of Immunology, 1998, 10.1002/(SICI)1521-4141(199805)28:05<1445::AID-IMMU1445>3.0.CO;2-P
- 2017 Outbreak of Ebola Virus Disease in Northern Democratic Republic of Congo., Muyembe JT, Van Herp M, Kikoo MJ, Kiyele M, Mondonge V, Mbuyi G, Okitandjate A, Corbeil J, Boucher N, Tshapenda G, Raymond F, Makiala S, Kapetshi J, Nsio J, The Journal of infectious diseases, 2019, 10.1093/infdis/jiz107
- Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species., Papadopoulou B, Ouellette M, Corbeil J, Rigault P, Boisvert S, Messier N, Smith M, Ubeda JM, Raymond F, Rochette A, BMC genomics, 2008, 10.1186/1471-2164-9-255
- First Complete Genome Sequence of Staphylococcus xylosus, a Meat Starter Culture and a Host to Propagate Staphylococcus aureus Phages., Moineau S, Corbeil J, Dewar K, Dumaresq J, Wasserscheid J, Plante PL, Tremblay DM, El Haddad L, Labrie SJ, Genome announcements, 2014, 10.1128/genomeA.00671-14
- Comparison of automated microarray detection with real-time PCR assays for detection of respiratory viruses in specimens obtained from children., Corbeil J, Boivin G, De Serres G, Wu WK, Boisvert S, Robitaille L, Boucher N, Carbonneau J, Raymond F, Journal of clinical microbiology, 2009, 10.1128/JCM.01297-08
- A lactococcal phage protein promotes viral propagation and alters the host proteomic response during infection, Moinea, S., Becher, D., Gagné, S.M., Corbeil, J., Shi, R., Tremblay, D.M., Rousseau, G.M., Plante, P.-L., Hamel, J., Otto, A., Maaß, S., Lemay, M.-L., Viruses, 2020, 10.3390/v12080797
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- Antimicrobial Resistance in the Environment: Towards Elucidating the Roles of Bioaerosols in Transmission and Detection of Antibacterial Resistance Genes., Duchaine C, Girard M, Gaucher ML, Culley AI, Corbeil J, Coleman BL, Charette SJ, Boissinot M, Bergeron MG, Badard T, Amato P, St-Germain MW, Rossi F, George PBL, Antibiotics (Basel, Switzerland), 2022, 10.3390/antibiotics11070974
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Contribution à l'enseignement aux cycles supérieurs
Étudiant(e)s dirigé(e)s*
Depuis 2020/04- Francis Brière - Doctorat - En cours
- Guillaume Edouard Marie Bachelot - Post-doctorat - En cours
- Elina Francovic-Fontaine - Doctorat - En cours
- Emanuel Paré - Doctorat - En cours
- Juan Manuel Dominguez - Doctorat - En cours
- Sewagnouin Rogia Kpanou - Doctorat - En cours
- Thibaud Godon - Doctorat - En cours
- Yesmine Sahnoun - Maîtrise avec mémoire - En cours
- Maxime Déraspe - Doctorat - 2021/09
- Pier-Luc Plante - Doctorat - 2021/09
- Jehane Abed - Doctorat - 2023/09
- Baptiste Bauvin - Doctorat - 2023/09
- Minja Velimirovic - Doctorat - 2024/09
Encadrement d'étudiant(e)s
Direction de recherche dans les domaines suivants :
- Médecine moléculaire
- Microbiologie-immunologie
- Santé publique — Santé communautaire
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