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Université Laval
Faculté de médecine

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Jacques Corbeil

Professeur titulaire

Jacques Corbeil
jacques.corbeil@fmed.ulaval.ca
Centre de recherche en infectiologie
Centre de recherche du CHU de Québec - Université Laval
Nutrition, santé et société (NUTRISS)
Centre de recherche en données massives
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Contribution à la recherche

Thématiques de recherche de la Faculté de médecine

  • Bioinformatique / données massives (big data)
  • Immunologie-infectiologie
  • Oncologie

Projets de recherche en cours

  • Identification of innate immune pathways as targets for immunomodulatory therapy in herpes simplex virus encephalitis - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2023-10-01 au 2028-09-30
  • PandemicStop-AI: for an accelerated response to pandemics - Fondation Canadienne pour l'innovation (La) - Fonds d'infrastructure de recherche en sciences biologiques (FIRSB), Université de Montréal, co-chercheur - 2024-03-01 au 2028-03-31
  • PandemicStop-AI: for an accelerated response to pandemics - Secrétariat des programmes interorganismes à l’intention des établissements - Fonds de recherche biomédical du Canada (FRBC), Université de Montréal, co-chercheur - 2024-03-01 au 2028-03-31
  • National Primate Center for Pandemic Preparedness (NPCPP) - Fondation Canadienne pour l'innovation (La), Ministère de l'Économie et de l'Innovation et de l'énergie, Ministère de l'Enseignement supérieur - Fonds d'infrastructure de recherche en sciences biologiques (FIRSB), co-chercheur - 2024-03-01 au 2028-03-31
  • Développement d'un système avancé de laboratoire sur puce multiplexé pour le criblage à haut débit utilisant la technologie des organopuces pour soutenir la découverte de nouveaux médicaments en IA - Linéaris Labs, Consortium québécois sur la découverte du médicament - SynergiQc, chercheur principal - 2025-06-01 au 2026-05-31
  • Unravelling the impact of diet on cardiovascular health in heterozygous familial hypercholesterolemia: a metabolomic approach - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2021-10-01 au 2025-09-30
  • Development of AI algorithms to support oncology drug development - MITACS Inc. - Accélération Québec (MITACS et gouvernement provincial), chercheur principal - 2025-02-03 au 2025-08-02

Financements des 2 dernières années

  • Soutien séjour France (Sorbonne Université) - 2 au 10 février 2025 - Université Laval - Fonds internes - Programme d'appui aux initiatives internationales, chercheur principal - 2025-01-16 au 2025-04-30
  • Development of an advanced multiplexed lab-on-a-chip system for highthroughput screening using organ-on-a-chip technology to support Al drug discovery - Secrétariat des programmes interorganismes à l’intention des établissements - Fonds d'excellence en recherche Apogée Canada, Université de Montréal, co-chercheur - 2024-03-01 au 2025-02-28
  • Extreme zooming on intestinal permeability and the western-style diet: Unravelling the role of dietary antigens on the prevalence of cardiometabolic and mental health diseases in the North - Secrétariat des programmes interorganismes à l’intention des établissements - Sentinelle Nord - Deuxième appel à projets majeurs, co-chercheur - 2020-11-01 au 2024-12-31
  • Chaire de recherche du Canada en Medical genomics - Instituts de recherche en santé du Canada - Chaires de recherche du Canada - Fonctionnement, chercheur principal - 2018-01-01 au 2024-12-31
  • Ecogenomics of mining areas for sustainable Canadian North (GENOSCAN) - Secrétariat des programmes interorganismes à l’intention des établissements - Sentinelle Nord - Deuxième appel à projets majeurs, co-chercheur - 2020-11-01 au 2024-12-31
  • Dissecting host-microbiome modifiers of type 2 diabetes risk - Objective 1.3 - Instituts de recherche en santé du Canada - Subvention d'équipe : Initiative canadienne microbiome 2 : Équipes de recherche, co-chercheur - 2019-11-01 au 2024-10-31
  • L'empreinte métabolomique plasmatique des produits laitiers: un reflet de leur consommation et une fenêtre sur leurs effets cardiométaboliques - Les producteurs laitiers du Canada - Subvention à la recherche en nutrition, co-chercheur - 2022-10-01 au 2024-09-30
  • Développement d’algorithmes d’IA pour soutenir le développement de médicaments oncologiques - MITACS Inc. - Accélération Québec (MITACS et gouvernement provincial), chercheur principal - 2024-04-01 au 2024-08-31
  • Exploration multi-omique des biopsies liquides pour dépister les porteurs de bactéries pathogènes et leurs résistances - Université Laval - Fonds internes - BDR - Contributions, chercheur principal - 2023-04-24 au 2024-04-23
  • Rôle des habitudes de vie sur le microbiote et la réponse clinique à l’immunothérapie en cancer de la vessie - Fonds de recherche du Québec - Santé - Projet subsidiaire - Nouveaux Centres et Instituts de recherche - Subventions régulières (pour fins de gestion au VRRCI), co-chercheur - 2023-04-20 au 2024-03-31
  • Observatoire international sur les impacts sociétaux de l'intelligence artificielle et du numérique - Fonds de recherche du Québec - Société et culture, Université Laval - Fonds internes - Appel à propositions : création d’un Observatoire international sur les impacts sociétaux de l’intelligence artificielle et du numérique, co-chercheur - 2018-04-01 au 2024-03-31
  • Antimicrobial resistance genes in bioaerosols in Canadian arctic, rural, and urban environments: sources, profiles, transport and fate - Conseil de recherches en sciences naturelles et génie Canada - Frontières de la découverte : Résistance aux antimicrobiens dans l'environnement, co-chercheur - 2019-12-01 au 2023-11-30
  • Validation de la mesure d’expression génique unicellulaire à partir d’un échantillon de tissu hépatique chez des sujets avec une suspicion clinique de stéatose hépatique non-alcoolique. - Fonds de recherche du Québec - Santé, co-chercheur - 2022-08-24 au 2023-08-23
  • Validation des marqueurs cellulaires ChromaLive sur modèles d'organopuces - MITACS Inc. - Accélération Québec (MITACS et gouvernement provincial), chercheur principal - 2022-12-12 au 2023-08-23
  • Déterminer la qualité de la polypharmacie chez les aînés : une approche basée sur l’intelligence artificielle - Conseil de recherches en sciences naturelles et génie Canada, Instituts de recherche en santé du Canada - Subvention de fonctionnement : Projets de recherche concertée sur la santé (avec le CRSNG), co-chercheur - 2020-04-01 au 2023-03-31
  • Prédire l'évolution de l'hépatite C par la fédération de données et l'intelligence artificielle : enjeux éthiques, juridiques, sociaux et de vie privée - Conseil de recherches en sciences naturelles et génie Canada, Instituts de recherche en santé du Canada, Conseil de recherches en sciences humaines du Canada - Subvention Projet, co-chercheur - 2019-04-01 au 2022-03-31
  • Deciphering breast cancer HER2-negativity with regard to HER2-targeted therapy - Instituts de recherche en santé du Canada - Volet Projet: Concours pilotes, co-chercheur - 2016-07-01 au 2021-06-30

Publications

  • Human Analysts at Superhuman Scales: What Has Friendly Software To Do?, Corbeil J, Laviolette F, Sosa CP, Long B, Behling S, Kandel M, Xia F, Boisvert S, Godzaridis É, Big data, 2013, 10.1089/big.2013.0031
  • HIV-induced apoptosis of activated primary CD4+ T lymphocytes is not mediated by Fas-Fas ligand, Spector, S.A., Brunner, T., Corbeil, J., Gozlan, J., Noraz, N., AIDS, 1997, 10.1097/00002030-199714000-00003
  • The next generation of automated microarray platforms for a multiplexed CYP2D6 assay, , Biochips as Pathways to Drug Discovery, 2006
  • The initial state of the human gut microbiome determines its reshaping by antibiotics., Corbeil J, Simard JL, Boudreau DK, Frenette J, Bérubé È, Giroux R, Plante PL, Leprohon P, Dridi B, Gingras H, Iqbal N, Déraspe M, Ouameur AA, Raymond F, The ISME journal, 2015, 10.1038/ismej.2015.148
  • Nonpathogenesis of simian immunodeficiency virus infection is associated with reduced inflammation and recruitment of plasmacytoid dendritic cells to lymph nodes, not to lack of an interferon type I response, during the acute phase., Estaquier J, Elbim C, Corbeil J, Zaunders J, Hurtrel B, Diop O, Lévy Y, Monceaux V, Cumont MC, Brussel A, Fay M, Laforge M, Campillo-Gimenez L, Journal of virology, 2009, 10.1128/JVI.01496-09
  • mTOR and HIF-1alpha-mediated tumor metabolism in an LKB1 mouse model of Peutz-Jeghers syndrome., Shaw RJ, Vera DR, Wu CL, Leblanc M, Wu S, Corbeil J, Vasquez DS, Shackelford DB, Proceedings of the National Academy of Sciences of the United States of America, 2009, 10.1073/pnas.0900465106
  • Gln-tRNAGln synthesis in a dynamic transamidosome from Helicobacter pylori, where GluRS2 hydrolyzes excess Glu-tRNAGln., Lapointe J, Kern D, Hendrickson TL, Diss G, Lorber B, Madore E, Corbeil J, Fischer F, Huot JL, Nucleic acids research, 2011, 10.1093/nar/gkr619
  • Improving the safety of Staphylococcus aureus polyvalent phages by their production on a Staphylococcus xylosus strain., Moineau S, St-Gelais D, Corbeil J, Labrie S, Katsarava R, Dumaresq J, Plante PL, Ben Abdallah N, El Haddad L, PloS one, 2014, 10.1371/journal.pone.0102600
  • Telomeric gene deletion and intrachromosomal amplification in antimony-resistant Leishmania., Ouellette M, Corbeil J, Mukhopadhyay R, Raymond F, Coelho AC, Monte-Neto RL, Boisvert S, Mukherjee A, Molecular microbiology, 2013, 10.1111/mmi.12178
  • Comparison of risk factors for human metapneumovirus and respiratory syncytial virus disease severity in young children., Boivin G, De Serres G, Frenette L, Caouette G, Corbeil J, Robitaille L, Raymond F, Ouakki M, Carbonneau J, Ouhoummane N, Hamelin MÈ, Papenburg J, The Journal of infectious diseases, 2012, 10.1093/infdis/jis333
  • Culture-enriched human gut microbiomes reveal core and accessory resistance genes., Corbeil J, Bergeron MG, Ouellette M, Roy PH, Huletsky A, Bérubé È, Kpanou SR, Plante PL, Déraspe M, Ouameur AA, Boissinot M, Raymond F, Microbiome, 2019, 10.1186/s40168-019-0669-7
  • The EcoChip 2: An Autonomous Sensor Platform for Multimodal Bio-environmental Monitoring of the Northern Habitat, Gosselin, B., Corbeil, J., Messaddeq, Y., Moineau, S., Tremblay, D., Bharucha, E., Hosseini, S.N., Bouzid, K., Ouazaa, K., Gagnon-Turcotte, G., Das, P.S., Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 2020, 10.1109/EMBC44109.2020.9176335
  • Genome-wide stochastic adaptive DNA amplification at direct and inverted DNA repeats in the parasite Leishmania., Ouellette M, Corbeil J, Papadopoulou B, Leprohon P, Lapointe A, Roy G, Gingras H, Plourde M, Mukherjee A, Raymond F, Ubeda JM, PLoS biology, 2014, 10.1371/journal.pbio.1001868
  • Productive HIV-1 infection of primary CD4+ T cells induces mitochondrial membrane permeabilization leading to a caspase-independent cell death., Estaquier J, Ameisen JC, Corbeil J, Schneider P, Hance AJ, Moutouh-de Parseval L, Lelièvre JD, Arnoult D, Petit F, The Journal of biological chemistry, 2001, 10.1074/jbc.m102671200
  • Characterization of cytokine gene expression associated with noninfectious human immunodeficiency virus retinopathy in human autopsy eyes., Freeman WR, Corbeil J, Schrier RD, Barron E, Hardiman G, Woelk C, Rought S, Cheng L, Kozak I, Retina (Philadelphia, Pa.), 2010, 10.1097/iae.0b013e3181c700f8
  • Cutting edge: a novel viral TNF receptor superfamily member in virulent strains of human cytomegalovirus., Ware CF, Tschopp J, Schneider P, Rooney I, Corbeil J, Lurain NS, Butrovich KD, Benedict CA, Journal of immunology (Baltimore, Md. : 1950), 1999
  • Label-free detection of biomolecular interactions in real time with a nano-porous silicon-based detection method., Corbeil J, Latterich M, Proteome science, 2008, 10.1186/1477-5956-6-31
  • Complete Genome Sequence of Escherichia coli Siphophage BRET., Moineau S, Aoussi S, Coulibaly DN, Soro BK, Koudou A, Corbeil J, Plante PL, Lemire N, Hutinet G, Tremblay DM, Addablah AA, Rousseau GM, Shao Y, Ngazoa-Kakou S, Microbiology resource announcements, 2019, 10.1128/MRA.01644-18
  • Bacterial meningitis and pneumococcal serotype distribution in children in cameroon., Tetanye E, Kobela M, Alcoba G, Raymond F, Corbeil J, Bescher BN, Taguebue J, Gervaix A, The Pediatric infectious disease journal, 2012, 10.1097/inf.0b013e318260552d
  • Machine learning analysis identifies genes differentiating triple negative breast cancers, Durocher, F., Diorio, C., Lambert, J.-P., Corbeil, J., Laviolette, F., Déraspe, M., Ouellette, G., Agbo, L., Osseni, M.A., Kothari, C., Scientific Reports, 2020, 10.1038/s41598-020-67525-1
  • HIV/SIV infection primes monocytes and dendritic cells for apoptosis., Estaquier J, Elbim C, Zaunders J, Corbeil J, Hurtrel B, Cumont MC, Monceaux V, Campillo-Gimenez L, Laforge M, PLoS pathogens, 2011, 10.1371/journal.ppat.1002087
  • Ray: simultaneous assembly of reads from a mix of high-throughput sequencing technologies., Corbeil J, Laviolette F, Boisvert S, Journal of computational biology : a journal of computational molecular cell biology, 2010, 10.1089/cmb.2009.0238
  • Interferon gene expression following HIV type 1 infection of monocyte-derived macrophages., Corbeil J, Richman DD, Kornbluth RS, Sasik R, Lozach J, Rought SE, Du P, Royer CD, Plotkin CR, Ottones F, Woelk CH, AIDS research and human retroviruses, 2004, 10.1089/aid.2004.20.1210
  • Effects of antiretroviral drugs on human immunodeficiency virus type 1-induced CD4(+) T-cell death., Corbeil J, Ameisen JC, Richman DD, Moutouh-De Parseval L, Brunner T, Petit F, Lelièvre JD, Estaquier J, Journal of virology, 2002, 10.1128/JVI.76.12.5966-5973.2002
  • Metagenomic profiling of Arctic microbial mat communities as nutrient scavenging and recycling systems, , Limnology and Oceanography, 2010, 10.4319/lo.2010.55.5.1901
  • Large-scale analysis of circulating glutamate and adipose gene expression in relation to abdominal obesity., Tchernof A, Grundberg E, Brière F, Corbeil J, Simon MM, Vijay J, Maltais-Payette I, Amino acids, 2022, 10.1007/s00726-022-03181-1
  • Comparison of Automated Microarray Detection with Real-Time PCR Assays for Detection of Respiratory Viruses in Specimens Obtained from Children., Corbeil J, Boivin G, De Serres G, Wu W, Boisvert S, Robitaille L, Boucher N, Carbonneau J, Raymond F, Journal of clinical microbiology, 2010, 10.1128/JCM.00255-10
  • MHC-NP: predicting peptides naturally processed by the MHC., Laviolette F, Corbeil J, Marchand M, Lacoste A, Drouin A, Giguère S, Journal of immunological methods, 2013, 10.1016/j.jim.2013.10.003
  • Symptomatology during previous SARS-CoV-2 infection and serostatus before vaccination influence the immunogenicity of BNT162b2 COVID-19 mRNA vaccine., Decaluwe H, Gilca V, Corbeil J, De Serres G, Cheng MP, Longtin Y, Savard P, McCormack D, Hamelin MÈ, Rabezanahary H, Carbonneau J, Adams K, Bourdin B, Nantel S, Frontiers in immunology, 2022, 10.3389/fimmu.2022.930252
  • Molecular evolution of respiratory syncytial virus fusion gene, Canada, 2006-2010., Boivin G, De Serres G, Bergeron MG, Corbeil J, Déry P, Paes BA, Ohoumanne N, Bouhy X, Isabel S, Hamelin MÈ, Carbonneau J, Papenburg J, Emerging infectious diseases, 2012, 10.3201/eid1801.110515
  • Identification and biophysical assessment of the molecular recognition mechanisms between the human haemopoietic cell kinase Src homology domain 3 and ALG-2-interacting protein X., Morelli X, Collette Y, Arold ST, Huang M, Corbeil J, Zimmermann P, Madore E, Perez J, Parrot I, Coursindel T, Restouin A, Lugari A, Opi S, Shi X, The Biochemical journal, 2010, 10.1042/bj20100314
  • Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy., Pauletti D, Barringer K, Cheeseman S, Sullivan J, Spector SA, Ignacio C, Looney D, Corbeil J, Havlir D, Richman DD, Journal of virology, 1994
  • The EcoChip: A Wireless Multi-Sensor Platform for Comprehensive Environmental Monitoring, Gosselin, B., Messaddeq, Y., Corbeil, J., Allard, M., Moineau, S., Raymond, F., Tremblay, D.M., Bharucha, E., Faucher, F., Morency, S., Lehoux, F., Sylvain, M., Proceedings - IEEE International Symposium on Circuits and Systems, 2018, 10.1109/ISCAS.2018.8351654
  • The role of surface CD4 in HIV-induced apoptosis., Richman DD, Corbeil J, Advances in experimental medicine and biology, 1995, 10.1007/978-1-4615-1995-9_8
  • Metagenomic analysis of stress genes in microbial mat communities from Antarctica and the High Arctic., Corbeil J, Vincent WF, Jungblut AD, Lovejoy C, Varin T, Applied and environmental microbiology, 2011, 10.1128/AEM.06354-11
  • Intracellular delivery of proteins with a new lipid-mediated delivery system., Corbeil J, Felgner PL, Reed JC, Kitada S, Wang Y, Zelphati O, The Journal of biological chemistry, 2001, 10.1074/jbc.m104920200
  • Draft Genome Sequence of Criibacterium bergeronii gen. nov., sp. nov., Strain CCRI-22567T, Isolated from a Vaginal Sample from a Woman with Bacterial Vaginosis., Omar RF, Boissinot M, Roy PH, Corbeil J, Raymond F, Boudreau DK, Bérubé È, Maheux AF, Genome announcements, 2016, 10.1128/genomeA.00959-16
  • Role of CD95-activated caspase-1 processing of IL-1beta in TCR-mediated proliferation of HIV-infected CD4(+) T cells., Estaquier J, Ameisen JC, Green DR, Pinon G, Moutouh-de Parseval L, Lelièvre JD, Corbeil J, Petit F, European journal of immunology, 2001, 10.1002/1521-4141(200112)31:12<3513::aid-immu3513>3.0.co;2-j
  • Productive infection and subsequent interaction of CD4-gp120 at the cellular membrane is required for HIV-induced apoptosis of CD4+ T cells, Richman, D.D., Corbeil, J., Journal of General Virology, 1995, 10.1099/0022-1317-76-3-681
  • Surface CD4 expression modulated by a cellular factor induced by HIV type 1 infection., Corbeil J, Richman D, Rought S, Du P, Sheeter D, AIDS research and human retroviruses, 2003, 10.1089/088922203762688621
  • A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis., Boivin G, Corbeil J, Carbonneau J, Venable MC, Piret J, Plante PL, Uyar O, Scientific reports, 2021, 10.1038/s41598-021-98047-z
  • Draft Genome Sequence of Romboutsia maritimum sp. nov. Strain CCRI-22766T, Isolated from Coastal Estuarine Mud., Bergeron MG, Omar RF, Broda D, Brightwell G, Corbeil J, Brodeur S, Raymond F, Boissinot M, Bérubé È, Boudreau DK, Maheux AF, Genome announcements, 2017, 10.1128/genomeA.01044-17
  • Microarray truths and consequences., Corbeil J, Woelk CH, Sásik R, Journal of molecular endocrinology, 2004, 10.1677/jme.0.0330001
  • Antiproliferative effects of enediynes on AIDS-derived Kaposi's sarcoma cells., Looney DJ, Nicolaou KC, Wrasidlo W, Richman DD, Corbeil J, Cancer research, 1994
  • Productive in vitro infection of human umbilical vein endothelial cells and three colon carcinoma cell lines with HIV‐1, COOPER, D.A., PENNY, R., RICHMAN, D.D., EDWARD, P.D., VASAK, E., MCQUEEN, P.W., EVANS, L.A., CORBEIL, J., Immunology and Cell Biology, 1995, 10.1111/j.1440-1711.1995.tb03847.x
  • Antiproliferative effect of retinoid compounds on Kaposi's sarcoma cells., Looney DJ, Richman DD, Rapaport E, Corbeil J, The Journal of clinical investigation, 1994, 10.1172/jci117190
  • Learning a peptide-protein binding affinity predictor with kernel ridge regression., Corbeil J, Drouin A, Laviolette F, Marchand M, Giguère S, BMC bioinformatics, 2013, 10.1186/1471-2105-14-82
  • The density of coreceptors at the surface of CD4+ T cells contributes to the extent of human immunodeficiency virus type 1 viral replication-mediated T cell death, Estaquier, J., Gervaix, A., Corbeil, J., Ameisen, J.-C., Arnoult, D., Perrin, L., Mammano, F., Petit, F., Lelièvre, J.-D., AIDS Research and Human Retroviruses, 2004, 10.1089/0889222042545045
  • Whole-genome comparative RNA expression profiling of axenic and intracellular amastigote forms of Leishmania infantum., Papadopoulou B, Ouellette M, Corbeil J, Raymond F, Rochette A, Molecular and biochemical parasitology, 2009, 10.1016/j.molbiopara.2008.12.012
  • Evolution of oseltamivir resistance mutations in Influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice., Boivin G, Corbeil J, Hamelin MÈ, Baz M, Carbonneau J, Plante PL, Abed Y, Pizzorno A, Antimicrobial agents and chemotherapy, 2014, 10.1128/AAC.02956-14
  • Turncoat antibodies unmasked in a model of autoimmune demyelination: from biology to therapy, Vallières L, Marignier R, Flanagan EP, Corbeil J, Dominguez JM, Park A, Jaworski J, Zhou Q, Béland L, Bourhoven L, Zhang Y, Morin F, Taghipour-Mirakmahaleh R, 2024, 10.1101/2024.12.03.623846
  • Modulation of gene expression in Leishmania drug resistant mutants as determined by targeted DNA microarrays., Ouellette M, Légaré D, Bergeron MG, Corbeil J, Papadopoulou B, Messier N, Richard D, Briand G, Peytavi R, El Fadili A, Marquis N, Brochu C, Trudel N, Guimond C, Nucleic acids research, 2003, 10.1093/nar/gkg806
  • Arctic microbial ecosystems and impacts of extreme warming during the International Polar Year, Mueller, D.R., Corbeil, J., Suttle, C.A., Laurion, I., Greer, C.W., Lovejoy, C., Whyte, L.G., Vincent, W.F., Polar Science, 2009, 10.1016/j.polar.2009.05.004
  • Optimization & Characterization of Interdigitated Electrodes for Microbial Growth Monitoring., Gosselin B, Corbeil J, Messaddeq Y, Bl-George P, Gagnon-Turcotte G, Sarati Das P, Hosseini SN, Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2021, 10.1109/embc46164.2021.9630056
  • HIV downregulates interferon-stimulated genes in primary macrophages., Woelk CH, Richman DD, Kornbluth RS, Corbeil J, Lozach J, Beliakova-Bethell N, Rought SE, Luong TQ, Du P, Wie SH, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2012, 10.1089/jir.2012.0052
  • Feature Selection with Conjunctions of Decision Stumps and Learning from Microarray Data., Corbeil J, Marchand M, Shah M, IEEE transactions on pattern analysis and machine intelligence, 2011, 10.1109/tpami.2011.82
  • The next generation of automated microarray platforms for a multiplexed CYP2D6 assay, Corbeil, J., Hardiman, G., Kureshy, F., Mahant, V., Fu, Y.-K.K., Kim, P., Biochips as Pathways to Drug Discovery, 2006
  • 2HAPI: a microarray data analysis system., Gribskov M, Corbeil J, Masys DR, Welsh JB, Patel H, Drewes S, Fink JL, Bioinformatics (Oxford, England), 2003, 10.1093/bioinformatics/btg169
  • The transcription factor Egr1 regulates the HIF-1alpha gene during hypoxia., de Belle I, Corbeil J, Robitaille L, Sasik R, Fortin J, Sperandio S, Molecular carcinogenesis, 2009, 10.1002/mc.20454
  • Making linked data SPARQL with the InterMine biological data warehouse, Dumontier, M., Micklem, G., Yehudi, Y., Sullivan, J., Lyne, R., Karra, K., Heimbach, J., Corbeil, J., Contrino, S., Clark-Casey, J., Cherry, J.M., Chadwick, M., Butano, D., Binkley, G., Déraspe, M., CEUR Workshop Proceedings, 2016
  • Learning self-supervised molecular representations for drug-drug interaction prediction., Corbeil J, Rousseau E, Dallaire P, Kpanou R, BMC bioinformatics, 2024, 10.1186/s12859-024-05643-7
  • Statistical analysis of high-density oligonucleotide arrays: a multiplicative noise model., Calvo E, Corbeil J, Sásik R, Bioinformatics (Oxford, England), 2002, 10.1093/bioinformatics/18.12.1633
  • Gene expression profiling and molecular characterization of antimony resistance in Leishmania amazonensis., Ouellette M, Frézard F, Melo MN, Corbeil J, Légaré D, Raymond F, Coelho AC, do Monte-Neto RL, PLoS neglected tropical diseases, 2011, 10.1371/journal.pntd.0001167
  • Genomic diversity and CRISPR-Cas systems in the cyanobacterium Nostoc in the High Arctic., Vincent WF, Corbeil J, Culley AI, Déraspe M, Francovic-Fontaine É, Lovejoy C, Nguyen GQ, Mohit V, Moineau S, Dion MB, Raymond F, Jungblut AD, Environmental microbiology, 2021, 10.1111/1462-2920.15481
  • Inhibition of ceramide-induced apoptosis by Bcl-2., Green DR, Reed JC, Kolesnick RN, Corbeil J, Miyashita T, McGahon AJ, Takayama S, Martin SJ, Cell death and differentiation, 1995
  • Nasopharyngeal carriage of individual Streptococcus pneumoniae serotypes during pediatric radiologically confirmed community acquired pneumonia following PCV7 introduction in Switzerland., Gervaix A, Galetto-Lacour A, Manzano S, Lacroix L, Alcoba G, Bouazza N, Maspoli V, Corbeil J, Raymond F, Robitaille L, Tabin R, Gehri M, Keitel K, Chappuy H, BMC infectious diseases, 2013, 10.1186/1471-2334-13-357
  • Gut metagenome profile of the Nunavik Inuit youth is distinct from industrial and non-industrial counterparts., Rousseau E, Corbeil J, Ayotte P, Poliakova N, Muckle G, Bélanger RE, Bergeron MG, Boissinot M, Plante PL, Mehdaoui F, Godon T, Abed JY, Communications biology, 2022, 10.1038/s42003-022-04372-y
  • Simian immunodeficiency virus infects follicular helper CD4 T cells in lymphoid tissues during pathogenic infection of pigtail macaques., Zaunders J, Kelleher AD, Kent SJ, Cooper DA, Corbeil J, Suzuki K, Wilson K, Estaquier J, De Rose R, Alcantara S, Bailey M, Weatherall C, Xu Y, Journal of virology, 2013, 10.1128/JVI.02497-12
  • Genomic characterization of a large outbreak of Legionella pneumophila serogroup 1 strains in Quebec City, 2012., Tremblay C, Corbeil J, Faucher SP, Desbiens F, Goupil-Sormany I, Huot C, Raymond F, Charest H, Marchand G, Cantin P, Mendis N, Plante PL, Lévesque S, PloS one, 2014, 10.1371/journal.pone.0103852
  • Inhibition of ceramide-induced apoptosis by Bcl-2, Green, D.R., Reed, J.C., Kolesnick, R.N., Corbeil, J., Miyashita, T., McGahon, A.J., Takayama, S., Martin, S.J., Cell Death and Differentiation, 1995
  • A lactococcal phage protein promotes viral propagation and alters the host proteomic response during infection, Moinea, S., Becher, D., Gagné, S.M., Corbeil, J., Shi, R., Tremblay, D.M., Rousseau, G.M., Plante, P.-L., Hamel, J., Otto, A., Maaß, S., Lemay, M.-L., Viruses, 2020, 10.3390/v12080797
  • Building an HIV data mashup using Bio2RDF., Corbeil J, Belleau F, Dumontier M, Nolin MA, Briefings in bioinformatics, 2011, 10.1093/bib/bbr003
  • Polyclonal proliferation and apoptosis of CCR5+ T lymphocytes during primary human immunodeficiency virus type 1 infection: regulation by interleukin (IL)-2, IL-15, and Bcl-2., Corbeil J, Little S, Estaquier J, Grey P, Smith DE, Cooper DA, Kelleher A, Leoni L, Genini D, Rought S, Reed JC, Kitada S, Moutouh-de Parseval L, Zaunders JJ, The Journal of infectious diseases, 2003, 10.1086/375030
  • Diminished somatostatin gene expression in individuals with HIV and major depressive disorder., HNRC (HIV Neurobehavioral Research Center), Masliah E, Grant I, Corbeil J, Young C, Atkinson JH, Salaria S, Everall IP, Neurology, 2006, 10.1212/01.wnl.0000244436.04036.a2
  • On the robustness of generalization of drug-drug interaction models., Corbeil J, Laviolette F, Tossou P, Osseni MA, Kpanou R, BMC bioinformatics, 2021, 10.1186/s12859-021-04398-9
  • Targeted Proteomics of Human Metapneumovirus in Clinical Samples and Viral Cultures., Moseley MA, Corbeil J, Boivin G, Plante PL, Robitaille L, Gerhardt G, Foster MW, Analytical chemistry, 2015, 10.1021/acs.analchem.5b01544
  • Mass spectra alignment using virtual lock-masses., Laviolette F, Corbeil J, Marchand M, Diorio C, Durocher F, Richard D, Gagnon D, Drouin A, Plante PL, Brochu F, Scientific reports, 2019, 10.1038/s41598-019-44923-8
  • Interpretable genotype-to-phenotype classifiers with performance guarantees, François Laviolette, Jacques Corbeil, Mario Marchand, Frédéric Raymond, Gaël Letarte, Alexandre Drouin, Scientific Reports, 2019, 10.1038/s41598-019-40561-2
  • Apoptosis in HIV-1 induced pathogenesis, Martin, S.J., Corbeil, J., FORUM - Trends in Experimental and Clinical Medicine, 1997
  • Effect of micromechanical stimulations on osteoblasts: development of a device simulating the mechanical situation at the bone-implant interface., Wild E, Corbeil J, Rakotomanana LR, Müller J, Pioletti DP, Journal of biomechanics, 2003, 10.1016/s0021-9290(02)00301-9
  • Large-scale gene expression analysis of osteoblasts cultured on three different Ti-6Al-4V surface treatments., Pioletti DP, Corbeil J, Gregson PJ, Browne M, Ku CH, Biomaterials, 2002, 10.1016/s0142-9612(02)00161-8
  • Mitogen-activated protein kinase pathways defend against bacterial pore-forming toxins., Aroian RV, van der Goot FG, Corbeil J, Sasik R, Abrami L, Huffman DL, Proceedings of the National Academy of Sciences of the United States of America, 2004, 10.1073/pnas.0404073101
  • Characterization of frataxin gene network in Friedreich's ataxia fibroblasts using the RNA-Seq technique., Tremblay JP, Corbeil J, Raymond F, Rousseau J, Chapdelaine P, Sanchez N, Mitochondrion, 2016, 10.1016/j.mito.2016.06.003
  • Serotyping of Streptococcus pneumoniae based on capsular genes polymorphisms., Gervaix A, Corbeil J, Tremblay C, Lefebvre B, Robitaille L, Allary R, Boucher N, Raymond F, PloS one, 2013, 10.1371/journal.pone.0076197
  • Gene expression profiling detects patterns of human macrophage responses following Mycobacterium tuberculosis infection., Guiney DG, Corbeil J, Rought SE, Wang JP, FEMS immunology and medical microbiology, 2003, 10.1016/s0928-8244(03)00223-2
  • Cytomegalovirus infection induces high levels of cyclins, phosphorylated Rb, and p53, leading to cell cycle arrest, Spector, D.H., Richman, D.D., Corbeil, J., Clark, C., Fortunato, E.A., Ruchti, F., Jault, J.-M., Jault, F.M., Journal of Virology, 1995, 10.1128/jvi.69.11.6697-6704.1995
  • HIV-1 coreceptor usage prediction without multiple alignments: an application of string kernels., Corbeil J, Laviolette F, Marchand M, Boisvert S, Retrovirology, 2008, 10.1186/1742-4690-5-110
  • On Selecting Robust Approaches for Learning Predictive Biomarkers in Metabolomics Data Sets, Alexandre Drouin, Pascal Germain, Jacques Corbeil, Pier-Luc Plante, Thibaud Godon, Analytical Chemistry, 2025, 10.1021/acs.analchem.5c01049
  • Serratia marcescens SCH909 as reservoir and source of genetic elements related to wide dissemination of antimicrobial resistance mechanisms. , Centrón D, Roy PH, Corbeil J, Quiroga MP, Álvarez VE, Déraspe M, Gambino AS, FEMS microbiology letters, 2021, 10.1093/femsle/fnab086
  • Productive in vitro infection of human umbilical vein endothelial cells and three colon carcinoma cell lines with HIV-1., Cooper DA, Penny R, Richman DD, Edward PD, Vasak E, McQueen PW, Evans LA, Corbeil J, Immunology and cell biology, 1995, 10.1038/icb.1995.22
  • Genome sequencing of the lizard parasite Leishmania tarentolae reveals loss of genes associated to the intracellular stage of human pathogenic species., Corbeil J, Ouellette M, Papadopoulou B, Tremblay MJ, Olivier M, Stanke M, Isnard A, Légaré D, Ritt JF, Roy G, Boisvert S, Raymond F, Nucleic acids research, 2011, 10.1093/nar/gkr834
  • First Complete Genome Sequence of Staphylococcus xylosus, a Meat Starter Culture and a Host to Propagate Staphylococcus aureus Phages., Moineau S, Corbeil J, Dewar K, Dumaresq J, Wasserscheid J, Plante PL, Tremblay DM, El Haddad L, Labrie SJ, Genome announcements, 2014, 10.1128/genomeA.00671-14
  • Flexible protein database based on amino acid k-mers., Corbeil J, Roy PH, Laviolette F, Boisvert S, Déraspe M, Scientific reports, 2022, 10.1038/s41598-022-12843-9
  • Correlation between Clostridium difficile bacterial load, commercial real-time PCR cycle thresholds, and results of diagnostic tests based on enzyme immunoassay and cell culture cytotoxicity assay., Longtin Y, Gervais P, Longtin J, Corbeil J, Raymond F, Dionne LL, Journal of clinical microbiology, 2013, 10.1128/JCM.01444-13
  • Gene amplification and point mutations in pyrimidine metabolic genes in 5-fluorouracil resistant Leishmania infantum., Ouellette M, Corbeil J, Légaré D, Leprohon P, Raymond F, Ritt JF, PLoS neglected tropical diseases, 2013, 10.1371/journal.pntd.0002564
  • A general framework for analyzing data from two short time-series microarray experiments., Corbeil J, Shah M, IEEE/ACM transactions on computational biology and bioinformatics, 2011, 10.1109/tcbb.2009.51
  • Associations between circulating amino acids and metabolic dysfunction-associated steatotic liver disease in individuals living with severe obesity., Tchernof A, Arsenault BJ, Corbeil J, Brière F, Couture C, Mitchell PL, Julien F, Marceau S, Biertho L, Gauthier MF, Bourgault J, Maltais-Payette I, Physiological reports, 2025, 10.14814/phy2.70171
  • Characterization of vancomycin-resistance vanD gene clusters in the human intestinal microbiota by metagenomics and culture-enriched metagenomics., Bergeron MG, Corbeil J, Boissinot M, Frenette J, Ouameur AA, Bérubé È, Raymond F, Boudreau DK, Huletsky A, Brochu E, JAC-antimicrobial resistance, 2023, 10.1093/jacamr/dlad026
  • Timing and Predictors of Loss of Infectivity Among Healthcare Workers With Mild Primary and Recurrent COVID-19: A Prospective Observational Cohort Study., Longtin Y, De Serres G, Corbeil J, Savard P, Villeneuve J, Beaulac SN, Parkes L, Longtin J, Levade I, Carazo S, Fafard J, Roy T, Charest H, Dzieciolowska S, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024, 10.1093/cid/ciad535
  • Genetic basis of hypersusceptibility to protease inhibitors and low replicative capacity of human immunodeficiency virus type 1 strains in primary infection., Little SJ, Hellmann NS, Corbeil J, Routy JP, Margolick JB, Conway B, Connick E, Collier AC, Markowitz M, Simon V, Daar ES, Good B, Frost SD, Leigh Brown AJ, Journal of virology, 2004, 10.1128/JVI.78.5.2242-2246.2004
  • Recombination leads to the rapid emergence of HIV-1 dually resistant mutants under selective drug pressure., Richman DD, Corbeil J, Moutouh L, Proceedings of the National Academy of Sciences of the United States of America, 1996, 10.1073/pnas.93.12.6106
  • Differential expression profiles of apoptosis-affecting genes in HIV-infected cell lines and patient T cells., Theofilopoulos AN, Corbeil J, Sabzevari H, Scheuring UJ, AIDS (London, England), 1999, 10.1097/00002030-199902040-00004
  • Use of keyword hierarchies to interpret gene expression patterns., Corbeil J, Klacansky I, Gribskov M, Lynn Fink J, Welsh JB, Masys DR, Bioinformatics (Oxford, England), 2001, 10.1093/bioinformatics/17.4.319
  • Draft Genome Sequence of a Sporulating and Motile Strain of Lachnotalea glycerini Isolated from Water in Québec City, Canada., Bergeron MG, Omar RF, Isabel S, Corbeil J, Brodeur S, Raymond F, Boissinot M, Bérubé È, Boudreau DK, Maheux AF, Genome announcements, 2017, 10.1128/genomeA.01059-17
  • Temporal gene regulation during HIV-1 infection of human CD4+ T cells., Gingeras T, Richman DD, Drenkow J, Huang D, Sasik R, Fink JL, Welsh JB, Masys DR, Ferguson M, Du P, Leoni L, Rought S, Genini D, Sheeter D, Corbeil J, Genome research, 2001, 10.1101/gr.180201
  • Criibacterium bergeronii gen. nov., sp. nov., a new member of the family Peptostreptococcaceae, isolated from human clinical samples. , Omar RF, Roy PH, Domingo MC, Corbeil J, Raymond F, Guay ÉF, Ducrey É, Hashimi A, Bernard KA, Brodeur S, Bérubé È, Abed JY, Boudreau DK, Maheux AF, International journal of systematic and evolutionary microbiology, 2019, 10.1099/ijsem.0.004691
  • Comparative gene expression analysis of blood and brain provides concurrent validation of SELENBP1 up-regulation in schizophrenia., Tsuang MT, Liew CC, Han M, Khanlou N, Sásik R, Corbeil J, Kremen WS, Everall IP, Glatt SJ, Proceedings of the National Academy of Sciences of the United States of America, 2005, 10.1073/pnas.0507666102
  • Ray Meta: scalable de novo metagenome assembly and profiling., Corbeil J, Laviolette F, Godzaridis E, Raymond F, Boisvert S, Genome biology, 2012, 10.1186/gb-2012-13-12-r122
  • Antimicrobial Resistance in the Environment: Towards Elucidating the Roles of Bioaerosols in Transmission and Detection of Antibacterial Resistance Genes., Duchaine C, Girard M, Gaucher ML, Culley AI, Corbeil J, Coleman BL, Charette SJ, Boissinot M, Bergeron MG, Badard T, Amato P, St-Germain MW, Rossi F, George PBL, Antibiotics (Basel, Switzerland), 2022, 10.3390/antibiotics11070974
  • Single-cell transcriptomics of the ventral posterolateral nucleus-enriched thalamic regions from HSV-1-infected mice reveal a novel microglia/microglia-like transcriptional response., Boivin G, Corbeil J, Tremblay ME, Vallières L, Ibáñez FG, Lapeyre L, Bordeleau M, Uyar O, Dominguez JM, Journal of neuroinflammation, 2022, 10.1186/s12974-022-02437-7
  • A new serotyping method of S. pneumoniae using an automated microarray-based assay., , International Conference on Prevention & Infection Control (ICPIC 2011), 2011, 10.1186/1753-6561-5-S6-O28
  • Multiple mutations in heterogeneous miltefosine-resistant Leishmania major population as determined by whole genome sequencing., Ouellette M, Corbeil J, Leprohon P, Mukherjee A, Boisvert S, Coelho AC, PLoS neglected tropical diseases, 2012, 10.1371/journal.pntd.0001512
  • Genome-Wide Screen for Haploinsufficient Cell Size Genes in the Opportunistic Yeast Candida albicans, Adnane Sellam, Jacques Corbeil, Michael A. Cook, Julien Chaillot, G3: Genes|Genomes|Genetics, 2017, 10.1534/g3.116.037986
  • Enhancement of HIV-1-induced syncytium formation in T cells by the tyrosyl kinase p56lck., Tremblay M, Corbeil J, Barbeau B, Briand G, Virology, 1997, 10.1006/viro.1997.8518
  • Predicting Ion Mobility Collision Cross-Sections Using a Deep Neural Network: DeepCCS., Corbeil J, Marchand M, Laviolette F, Baker ES, McLean JA, May JC, Francovic-Fontaine É, Plante PL, Analytical chemistry, 2019, 10.1021/acs.analchem.8b05821
  • TRAF6 and IRF7 control HIV replication in macrophages., Corbeil J, Estaquier J, Woelk CH, Shah M, Allary R, Robitaille L, Sirois M, PloS one, 2011, 10.1371/journal.pone.0028125
  • The EcoChip: A Wireless Multi-Sensor Platform for Comprehensive Environmental Monitoring., Gosselin B, Messaddeq Y, Corbeil J, Allard M, Moineau S, Sarrazin D, Raymond F, Tremblay DM, Bharucha E, Faucher F, Morency S, Lehoux F, Sylvain M, IEEE transactions on biomedical circuits and systems, 2018, 10.1109/tbcas.2018.2878404
  • Human viral pathogens are pervasive in wastewater treatment center aerosols., Duchaine C, Culley A, Corbeil J, Lavoie J, Dion-Dupont V, Veillette M, Brisebois E, Journal of environmental sciences (China), 2017, 10.1016/j.jes.2017.07.015
  • MOT: a Multi-Omics Transformer for multiclass classification tumour types predictions, Corbeil J, Laviolette F, Tossou P, Osseni MA, 2022, 10.21203/rs.3.rs-1348696/v2
  • Endonucleases: tools to correct the dystrophin gene., Tremblay JP, Montpetit A, Corbeil J, Almeida LP, Boisvert S, Chapdelaine P, Rousseau J, The journal of gene medicine, 2011, 10.1002/jgm.1611
  • Bendamustine (Treanda) displays a distinct pattern of cytotoxicity and unique mechanistic features compared with other alkylating agents., Niemeyer CC, Elliott G, Corbeil J, Zeller RW, Bendall HH, Reifert J, Bailey B, Leoni LM, Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, 10.1158/1078-0432.ccr-07-1061
  • Fast protein database as a service with kAAmer, Jacques Corbeil, Paul H Roy, François Laviolette, Sébastien Boisvert, Maxime Déraspe, 2020, 10.1101/2020.04.01.019984
  • Intra-uterine growth restriction and the programming of left ventricular remodelling in female rats., Brochu M, Corbeil J, Comte B, Chorvatova A, Calvo E, Battista MC, The Journal of physiology, 2005, 10.1113/jphysiol.2004.078139
  • The REinfection in COVID-19 Estimation of Risk (RECOVER) study: Reinfection and serology dynamics in a cohort of Canadian healthcare workers., Quach-Thanh C, Nantel S, Bourdin B, Adams K, Tadount F, Carbonneau J, Hamelin MÈ, Cheng MP, Savard P, Decaluwe H, McCormack D, Longtin Y, Boivin G, Racine É, Influenza and other respiratory viruses, 2022, 10.1111/irv.12997
  • Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species., Korf IF, Corbeil J, Chou WC, Chitsaz H, Chikhi R, Chapuis G, Chapman JA, Boisvert S, Birol I, Bechner M, Baranay P, Alexandrov A, Fass JN, Bradnam KR, GigaScience, 2013, 10.1186/2047-217X-2-10
  • Chipping Away at HIV Pathogenesis, , Pathogen Genomics, 2002, 10.1007/978-1-59259-172-5_2
  • Exploring polypharmacy with artificial intelligence: data analysis protocol., Simard M, Corbeil J, Savard AM, Laviolette F, Gagné C, Després P, Bureau A, Talbot D, Chiu Y, Bukhtiyarova O, Deziel PL, Durand A, Khoury R, Sirois C, BMC medical informatics and decision making, 2021, 10.1186/s12911-021-01583-x
  • Complete Genome Sequence of Streptococcus thermophilus SMQ-301, a Model Strain for Phage-Host Interactions., Moineau S, Corbeil J, Dewar K, Wasserscheid J, Plante PL, Tremblay DM, Labrie SJ, Genome announcements, 2015, 10.1128/genomeA.00480-15
  • Enhanced antiproliferative effects of alkoxyalkyl esters of cidofovir in human cervical cancer cells in vitro., Corbeil J, Beadle JR, Trahan J, Aldern KA, Rought S, Hostetler KY, Molecular cancer therapeutics, 2006, 10.1158/1535-7163.mct-05-0200
  • Clostridium difficile: Investigating Transmission Patterns Between Infected and Colonized Patients Using Whole Genome Sequencing., Loo VG, Dascal A, Bourgault AM, Schiller I, Dendukuri N, Frost E, Toye B, Michaud S, Crook DW, Wilcox MH, Walker AS, Raymond F, Corbeil J, Eyre DW, Kong LY, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 10.1093/cid/ciy457
  • HIV-induced apoptosis requires the CD4 receptor cytoplasmic tail and is accelerated by interaction of CD4 with p56lck., Richman DD, Tremblay M, Corbeil J, The Journal of experimental medicine, 1996, 10.1084/jem.183.1.39
  • Complete Genome Sequences of Klebsiella michiganensis and Citrobacter farmeri, KPC-2-Producers Serially Isolated from a Single Patient. , Roy PH, Bergeron MG, Corbeil J, Boissinot M, Dewar K, D'Iorio M, Bérubé È, Déraspe M, Abed JY, Antibiotics (Basel, Switzerland), 2021, 10.3390/antibiotics10111408
  • Communities of Phytoplankton Viruses across the Transition Zone of the St. Lawrence Estuary, Alexander Culley, Jacques Corbeil, Martyne Audet, Vani Mohit, Mary Thaler, Alice Lévesque, Frédéric Raymond, Myriam Labbé, Viruses, 2018, 10.3390/v10120672
  • Machine learning assisted design of highly active peptides for drug discovery., Corbeil J, Biron É, Liang X, Moineau S, Tremblay D, Marchand M, Laviolette F, Giguère S, PLoS computational biology, 2015, 10.1371/journal.pcbi.1004074
  • Epitope mapping of the 2009 pandemic and the A/Brisbane/59/2007 seasonal (H1N1) influenza virus haemagglutinins using mAbs and escape mutants., Boivin G, Corbeil J, Abed Y, Retamal M, The Journal of general virology, 2014, 10.1099/vir.0.067819-0
  • Draft Genome Sequence of Romboutsia weinsteinii sp. nov. Strain CCRI-19649T Isolated from Surface Water., Bergeron MG, Omar RF, Corbeil J, Raymond F, Cantin P, Boissinot M, Bérubé È, Boudreau DK, Maheux AF, Genome announcements, 2017, 10.1128/genomeA.00901-17
  • Global Mapping of the Macrophage-HIV-1 Transcriptome Reveals that Productive Infection Induces Remodeling of Host Cell DNA and Chromatin., Tremblay MJ, Corbeil J, Roy MA, Barat C, Lodge R, Raymond F, Ouellet M, Breton Y, Joly-Beauparlant C, Deshiere A, Scientific reports, 2017, 10.1038/s41598-017-05566-9
  • Molecular and cellular analysis of human immunodeficiency virus-induced apoptosis in lymphoblastoid T-cell-line-expressing wild-type and mutated CD4 receptors., Corbeil J, Richman DD, Estaquier J, Moutouh L, Journal of virology, 1998, 10.1128/jvi.72.10.8061-8072.1998
  • Methamphetamine stimulates interferon inducible genes in HIV infected brain., HNRC Group, Masliah E, Grant I, Fox H, Sasik R, Corbeil J, Roberts E, Salaria S, Everall I, Journal of neuroimmunology, 2005, 10.1016/j.jneuroim.2005.09.009
  • The resistome of Pseudomonas aeruginosa in relationship to phenotypic susceptibility., Gardner H, Corbeil J, Alm RA, Roy PH, Whiteaker JD, McLaughlin RE, Déraspe M, Kos VN, Antimicrobial agents and chemotherapy, 2014, 10.1128/AAC.03954-14
  • Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species., Papadopoulou B, Ouellette M, Corbeil J, Rigault P, Boisvert S, Messier N, Smith M, Ubeda JM, Raymond F, Rochette A, BMC genomics, 2008, 10.1186/1471-2164-9-255
  • A new perspective on V3 phenotype prediction., Corbeil J, Richman D, Good B, Pillai S, AIDS research and human retroviruses, 2003, 10.1089/088922203762688658
  • Predictive computational phenotyping and biomarker discovery using reference-free genome comparisons., Corbeil J, Laviolette F, Bourgault AM, Loo VG, Tyers M, Marchand M, Déraspe M, Giguère S, Drouin A, BMC genomics, 2016, 10.1186/s12864-016-2889-6
  • 2017 Outbreak of Ebola Virus Disease in Northern Democratic Republic of Congo., Muyembe JT, Van Herp M, Kikoo MJ, Mondonge V, Kiyele M, Mbuyi G, Okitandjate A, Corbeil J, Boucher N, Tshapenda G, Raymond F, Makiala S, Kapetshi J, Nsio J, The Journal of infectious diseases, 2019, 10.1093/infdis/jiz107
  • Clostridium difficile: Investigating Transmission Patterns Between Symptomatic and Asymptomatic Patients Using Whole Genome Sequencing., Loo V, Toye B, Michaud S, Dascal A, Bourgault A, Wilcox M, Walker AS, Raymond F, Corbeil J, Eyre D, Kong LY, Open forum infectious diseases, 2017, 10.1093/ofid/ofx162.000
  • Gene expression analysis of osteoblastic cells contacted by orthopedic implant particles., Corbeil J, Du P, Takei H, Genini D, Leoni L, Pioletti DP, Journal of biomedical materials research, 2002, 10.1002/jbm.10218
  • Gene expression modulation is associated with gene amplification, supernumerary chromosomes and chromosome loss in antimony-resistant Leishmania infantum., Ouellette M, Corbeil J, Hardiman G, Madore E, Raymond F, Légaré D, Leprohon P, Nucleic acids research, 2009, 10.1093/nar/gkn1069
  • Modulation of gene expression in drug resistant Leishmania is associated with gene amplification, gene deletion and chromosome aneuploidy., Ouellette M, Papadopoulou B, Olivier M, Tremblay MJ, Corbeil J, Rigault P, Boisvert S, Ouameur AA, Raymond F, Légaré D, Ubeda JM, Genome biology, 2008, 10.1186/gb-2008-9-7-r115
  • R5 and X4 HIV viruses differentially modulate host gene expression in resting CD4+ T cells., Corbeil J, Fortin J, Estaquier J, Sasik R, Robitaille L, Sirois M, AIDS research and human retroviruses, 2008, 10.1089/aid.2007.0120
  • Gene expression modulation and the molecular mechanisms involved in Nelfinavir resistance in Leishmania donovani axenic amastigotes., Tremblay MJ, Ouellette M, Corbeil J, Jalaguier P, Ritt JF, Raymond F, Lodge R, Kumar P, Molecular microbiology, 2013, 10.1111/mmi.12298
  • Timing and Predictors of Loss of Infectivity among Healthcare Workers with Primary and Recurrent COVID-19: a Prospective Observational Cohort Study, Longtin Y, Serres GD, Corbeil J, Savard P, Villeneuve J, Beaulac SN, Parkes L, Longtin J, Levade I, Carazo S, Fafard J, Roy T, Charest H, Dzieciolowska S, 2023, 10.1101/2023.06.16.23291449
  • Conjugation of protein to immunostimulatory DNA results in a rapid, long-lasting and potent induction of cell-mediated and humoral immunity., , European journal of immunology, 2000, 10.1002/1521-4141(200007)30:7<1939::aid-immu1939>3.0.co;2-#
  • Comparison of automated microarray detection with real-time PCR assays for detection of respiratory viruses in specimens obtained from children., Corbeil J, Boivin G, De Serres G, Wu WK, Boisvert S, Robitaille L, Boucher N, Carbonneau J, Raymond F, Journal of clinical microbiology, 2009, 10.1128/JCM.01297-08
  • Streamlining CRISPR spacer-based bacterial host predictions to decipher the viral dark matter., Moineau S, Corbeil J, Shah SA, Zufferey E, Plante PL, Dion MB, Nucleic acids research, 2021, 10.1093/nar/gkab133
  • A new Microviridae phage isolated from a failed biotechnological process driven by Escherichia coli., Moineau S, Plante PL, Corbeil J, Tremblay DM, Dupuis MÈ, Labrie SJ, Applied and environmental microbiology, 2014, 10.1128/AEM.01365-14
  • The density of coreceptors at the surface of CD4+ T cells contributes to the extent of human immunodeficiency virus type 1 viral replication-mediated T cell death., Estaquier J, Gervaix A, Corbeil J, Ameisen JC, Arnoult D, Mammano F, Perrin L, Petit F, Lelièvre JD, AIDS research and human retroviruses, 2004, 10.1089/aid.2004.20.1230
  • Studies on fibronectin in inflammatory vs non-inflammatory polymorphonuclear leucocytes of patients with rheumatoid arthritis. II. Synthesis and release of fibronectin in vitro., Latulippe L, Corbeil J, Audette M, Beaulieu AD, Menard C, Clinical and experimental immunology, 1985
  • Partial recovery of microbiomes after antibiotic treatment., Corbeil J, Bergeron MG, Boissinot M, Déraspe M, Raymond F, Gut microbes, 2016, 10.1080/19490976.2016.1216747
  • A new reporter cell line to monitor HIV infection and drug susceptibility in vitro., Corbeil J, Wong-Staal F, Richman DD, Leoni LM, West D, Gervaix A, Proceedings of the National Academy of Sciences of the United States of America, 1997, 10.1073/pnas.94.9.4653
  • Culture and properties of cells derived from Kaposi sarcoma., Penny R, Cooper DA, Vasak E, Evans LA, Corbeil J, Journal of immunology (Baltimore, Md. : 1950), 1991
  • Early modifications of host cell gene expression induced by HIV-1, Theofilopoulos, A.N., Mosier, D.E., Corbeil, J., Scheuring, U.J., AIDS, 1998, 10.1097/00002030-199806000-00004
  • Phylogenomic insights into evolutionary trajectories of multidrug resistant S. pneumoniae CC271 over a period of 14 years in China., Feng J, Li Y, Corbeil J, Zhang J, Li C, Wei D, Zhang G, Coelho AC, Wu Q, Wang C, Cui L, Song Y, Zeng Y, Genome medicine, 2023, 10.1186/s13073-023-01200-8
  • Substitution of dietary monounsaturated fatty acids from olive oil for saturated fatty acids from lard increases low-density lipoprotein apolipoprotein B-100 fractional catabolic rate in subjects with dyslipidemia associated with insulin resistance: a randomized controlled trial., Couture P, Lamarche B, Schaefer EJ, Charest A, Lemelin V, Corbeil J, Drouin-Chartier JP, Rancourt-Bouchard M, Tremblay AJ, Brière F, Desjardins LC, The American journal of clinical nutrition, 2024, 10.1016/j.ajcnut.2024.03.015
  • HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism., Leoni LM, Corbeil J, Carson DA, Richman DD, Kroemer G, Susin SA, Zaunders JJ, Rought S, Sheeter D, Genini D, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2000, 10.1096/fj.00-0336fje
  • Draft genome of the American Eel (Anguilla rostrata)., Bernatchez L, Audet C, Corbeil J, Boisvert S, Letourneau L, Gaudin J, Normandeau E, Laporte M, Pavey SA, Molecular ecology resources, 2017, 10.1111/1755-0998.12608
  • The Ick protein tyrosine kinase is not involved in antibody-mediated CD4 (CDR3-loop) signal transduction that inhibits HIV-1 transcription, Devaux, C., Mesnard, J.-M., Robert-Hebmann, V., Corbeil, J., Coudronnière, N., European Journal of Immunology, 1998, 10.1002/(SICI)1521-4141(199805)28:05<1445::AID-IMMU1445>3.0.CO;2-P
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  • Sand DNA—a genetic library of life at the water's edge, , Marine Ecology Progress Series, 2005, 10.3354/meps301009
  • Mendelian Randomization Analysis Identifies Blood Tyrosine Levels as a Biomarker of Non-Alcoholic Fatty Liver Disease., Arsenault BJ, Mathieu P, Mitchell PL, Couture C, Manikpurage HD, Gagnon E, Bourgault J, Abner E, Ghodsian N, Brière F, Taba N, Maltais-Payette I, Gobeil É, Metabolites, 2022, 10.3390/metabo12050440
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  • Phenotypic and Genetic Characterization of the Cheese Ripening Yeast Geotrichum candidum, Labrie, S., Frenette, M., Dugat-Bony, E., Corbeil, J., Plante, P.-L., Lessard, M.-H., Vignola, S., Perkins, V., Frontiers in Microbiology, 2020, 10.3389/fmicb.2020.00737

Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2020/07
  • Vahid Karamzadeh - Post-doctorat - En cours
  • Maxime Déraspe - Post-doctorat - En cours
  • Juan Manuel Dominguez - Doctorat - En cours
  • Yesmine Sahnoun - Maîtrise avec mémoire - En cours
  • Thibaud Godon - Doctorat - En cours
  • Claudia Carpentier - Post-doctorat - En cours
  • Anthony Lavertu - Maîtrise avec mémoire - En cours
  • Sewagnouin Rogia Kpanou - Doctorat - En cours
  • Elina Francovic-Fontaine - Doctorat - En cours
  • Francis Brière - Doctorat - En cours
  • Emanuel Paré - Doctorat - En cours
  • Elsa Rousseau - Post-doctorat - En cours
  • Paul George - Post-doctorat - En cours
  • Guillaume Edouard Marie Bachelot - Post-doctorat - En cours
  • Pier-Luc Plante - Doctorat - 2021/09
  • Baptiste Bauvin - Doctorat - 2023/09
  • Jehane Abed - Doctorat - 2023/09
  • Minja Velimirovic - Doctorat - 2024/09

Encadrement d'étudiant(e)s

Direction de recherche dans les domaines suivants :

  • Médecine moléculaire
  • Microbiologie-immunologie
  • Santé publique — Santé communautaire

En savoir plus sur les programmes

Disponibilité d'encadrement d'étudiant(e)s

Ce (cette) professeur(e) est présentement à la recherche d'étudiant(e)s.

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*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.
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Vice-décanat à la recherche et à l'innovation

Pavillon Ferdinand-Vandry
Université Laval
1050, avenue de la Médecine, local 4623
Québec (Québec) G1V 0A6
Canada

Renseignements - Secrétariat
418 656-2690
secretariatvdri@fmed.ulaval.ca

Catherine Mercier
Vice-doyenne à la recherche et à l'innovation