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Igor Timofeev

Professeur titulaire

Igor.Timofeev@fmed.ulaval.ca

Site personnel

Département de psychiatrie et de neurosciences

Centre thématique de recherche en neurosciences

Centre de recherche CERVO

Partager la fiche :

Contribution à la recherche

Thématiques de recherche de la Faculté de médecine

Bioinformatique / données massives (big data)
Neurosciences et santé mentale

Projets de recherche en cours

Thalamic gating during sleep oscillations - Conseil de recherches en sciences naturelles et génie Canada - Subventions à la découverte SD (individuelles et d'équipe), chercheur principal - 2024-04-01 au 2029-03-31
Modulation of cortical excitability with transcranial direct current stimulation: toward prevention of trauma-induced neocortical epileptogenesis - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2022-10-01 au 2027-09-30

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Financements des 2 dernières années

Multiscale modeling and large-scale recordings of trauma-induced epileptogensis - National Institute of Health (USA) - Subvention de recherche, Salk Institute for Biological Studies (The), co-chercheur - 2018-09-30 au 2023-06-30
Thalamic gating during sleep oscillations - Conseil de recherches en sciences naturelles et génie Canada, Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC) - Subventions à la découverte SD (individuelles et d'équipe), chercheur principal - 2018-04-01 au 2023-03-31

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Publications

Cortical hyperpolarization-activated depolarizing current takes part in the generation of focal paroxysmal activities, Steriade, M., Sejnowski, T., Bazhenov, M., Timofeev, I., Proceedings of the National Academy of Sciences of the United States of America, 2002, 10.1073/pnas.132259899
Extracellular Potassium Dynamics and Epileptogenesis, Bazhenov, M., Sejnowski, T.J., Timofeev, I., Fröhlich, F., Computational Neuroscience in Epilepsy, 2008, 10.1016/B978-012373649-9.50029-6
Spatio-temporal properties of sleep slow waves and implications for development., Salome Kurth, Riedner BA, Huber R, LeBourgeois MK, Sarah F. Schoch, Timofeev I, Current opinion in physiology, 2020, 10.1016/j.cophys.2020.01.007
Origin of active states in local neocortical networks during slow sleep oscillation, Timofeev, I., Volgushev, M., Chauvette, S., Cerebral Cortex, 2010, 10.1093/cercor/bhq009
DeltaFosB and Preclinical Binge Eating, Igor Timofeev, Richard Quansah Amissah, Eating Disorders, 2023, 10.1007/978-3-031-16691-4_54
Extracellular Ca2+ fluctuations in vivo affect afterhyperpolarization potential and modify firing patterns of neocortical neurons, Timofeev, I., Seigneur, J., Chauvette, S., Crochet, S., Boucetta, S., Experimental Neurology, 2013, 10.1016/j.expneurol.2012.12.001
Impact of intrinsic properties and synaptic factors on the activity of neocortical networks in vivo, Steriade, M., Grenier, F., Timofeev, I., Journal of Physiology Paris, 2000, 10.1016/S0928-4257(00)01097-4
Neuronal plasticity and thalamocortical sleep and waking oscillations, Timofeev, I., Progress in Brain Research, 2011, 10.1016/B978-0-444-53839-0.00009-0
Spiking-bursting activity in the thalamic reticular nucleus initiates sequences of spindle oscillations in thalamic networks, Sejnowski, T., Steriade, M., Timofeev, I., Bazhenov, M., Journal of Neurophysiology, 2000
Age dependency of trauma-induced neocortical epileptogenesis, Grand, L.B., Chauvette, S., Bazhenov, M., Sejnowski, T.J., Timofeev, I., Frontiers in Cellular Neuroscience, 2013, 10.3389/fncel.2013.00154
Synaptic Interactions between Thalamic and Cortical Inputs onto Cortical Neurons in Vivo, Steriade, M., Timofeev, I., Crochet, S., Fuentealba, P., Journal of Neurophysiology, 2004, 10.1152/jn.01105.2003
Inhibition determines membrane potential dynamics and controls action potential generation in awake and sleeping cat cortex, Destexhe, A., Timofeev, I., Pospischil, M., Rudolph, M., Journal of Neuroscience, 2007, 10.1523/JNEUROSCI.4652-06.2007
Cellular and neurochemical basis of sleep stages in the thalamocortical network, Bazhenov, M., Halgren, E., Cash, S.S., Timofeev, I., Soltani, S., Shamie, I., Chauvette, S., Krishnan, G.P., eLife, 2016, 10.7554/eLife.18607
Cortical and thalamic components of neocortical kindling-induced epileptogenesis in behaving cats, Timofeev, I., Fröhlich, F., Cissé, Y., Nita, D.A., Experimental Neurology, 2008, 10.1016/j.expneurol.2008.02.028
Focal generation of paroxysmal fast runs during electrographic seizures, Timofeev, I., Bazhenov, M., Chauvette, S., Boucetta, S., Epilepsia, 2008, 10.1111/j.1528-1167.2008.01707.x
Partial cortical deafferentation promotes development of paroxysmal activity, Timofeev, I., Steriade, M., Topolnik, L., Cerebral Cortex, 2003, 10.1093/cercor/13.8.883
Modeling thalamocortical cell: Impact of Ca²⁺ channel distribution and cell geometry on firing pattern, Timofeev, I., Kröger, H., Zomorrodi, R., Frontiers in Computational Neuroscience, 2008, 10.3389/neuro.10.005.2008
Corticothalamic feedback controls sleep spindle duration in vivo, Bazhenov, M., Sejnowski, T., Timofeev, I., Lemieux, M., Baker, T., Bonjean, M., Journal of Neuroscience, 2011, 10.1523/JNEUROSCI.0077-11.2011
Focal synchronization of ripples (80-200 Hz) in neocortex and their neuronal correlates, Steriade, M., Timofeev, I., Grenier, F., Journal of Neurophysiology, 2001
Precise long-range synchronization of activity and silence in neocortical neurons during slow-wave sleep, Timofeev, I., Mukovski, M., Chauvette, S., Volgushev, M., Journal of Neuroscience, 2006, 10.1523/JNEUROSCI.0279-06.2006
Potassium model for slow (2-3 Hz) in vivo neocortical paroxysmal oscillations, Sejnowski, T.J., Steriade, M., Timofeev, I., Bazhenov, M., Journal of Neurophysiology, 2004, 10.1152/jn.00529.2003
Slow wave detection in sleeping mice: Comparison of traditional and machine learning methods, Timofeev, I., Chauvette, S., Soltani, S., Bukhtiyarova, O., Journal of Neuroscience Methods, 2019, 10.1016/j.jneumeth.2018.08.016
The reuniens nucleus of the thalamus facilitates hippocampo-cortical dialogue during sleep, Igor Timofeev, Maryam Ghorbani, Sylvain Chauvette, Elian Proulx, Amirmohammad Azarmehri, Diellor Basha, eLife, 2025, 10.7554/eLife.90826.3
Mechanisms of long-lasting hyperpolarizations underlying slow sleep oscillations in cat corticothalamic networks, Steriade, M., Timofeev, I., Contreras, D., Journal of Physiology, 1996, 10.1113/jphysiol.1996.sp021488
Cortical and thalamic components of augmenting responses: A modeling study, Sejnowski, T.J., Steriade, M., Timofeev, I., Bazhenov, M., Houweling, A.R., Neurocomputing, 1999, 10.1016/S0925-2312(98)00142-8
New class of reduced computationally efficient neuronal models for large-scale simulations of brain dynamics, Bazhenov, M., Timofeev, I., Rulkov, N., Chauvette, S., Krishnan, G., Komarov, M., Journal of Computational Neuroscience, 2018, 10.1007/s10827-017-0663-7
Mircea Steriade (1924-2006)., Timofeev, I., Neuroscience, 2006, 10.1016/j.neuroscience.2006.08.042
Short-and medium-term plasticity associated with augmenting responses in cortical slabs and spindles in intact cortex of cats in vivo, Steriade, M., Sejnowski, T.J., Houweling, A.R., Bazhenov, M., Grenier, F., Timofeev, I., Journal of Physiology, 2002, 10.1113/jphysiol.2001.013479
Interneuron-mediated inhibition synchronizes neuronal activity during slow oscillation, Bazhenov, M., Timofeev, I., Skorheim, S., Chauvette, S., Chen, J.-Y., Journal of Physiology, 2012, 10.1113/jphysiol.2012.227462
State-dependent slow outlasting activities following neocortical kindling in cats, Timofeev, I., Cissé, Y., Nita, D.A., Experimental Neurology, 2008, 10.1016/j.expneurol.2008.02.010
Synaptic impairment induced by paroxysmal ionic conditions in neocortex, Timofeev, I., Seigneur, J., Epilepsia, 2011, 10.1111/j.1528-1167.2010.02784.x
Neocortical very fast oscillations (ripples, 80-200 Hz) during seizures: Intracellular correlates, Steriade, M., Timofeev, I., Grenier, F., Journal of Neurophysiology, 2003, 10.1152/jn.00420.2002
Neocortical synchronization, Sejnowski, T., Seigneur, J., Bazhenov, M., Timofeev, I., Epilepsia, 2010, 10.1111/j.1528-1167.2010.02804.x
Contribution of intrinsic and synaptic factors in the desynchronization of thalamic oscillatory activity, Steriade, M., Sejnowski, T.J., Bazhenov, M., Timofeev, I., Thalamus and Related Systems, 2001, 10.1016/S1472-9288(01)00004-8
A Wireless Electro-Optic Platform for Multimodal Electrophysiology and Optogenetics in Freely Moving Rodents, , Frontiers in Neuroscience, 2021, 10.3389/fnins.2021.718478
Compulsive Eating in a Rat Model of Binge Eating Disorder Under Conditioned Fear and Exploration of Neural Mechanisms With c-fos mRNA Expression, Igor Timofeev, Elena Timofeeva, Geneviève Guèvremont, Sandrine Chometton, Zhi Fei Li, Frontiers in Neuroscience, 2021, 10.3389/fnins.2021.777572
Modulation of synaptic transmission in neocortex by network activities, Timofeev, I., Boucetta, S., Chauvette, S., Crochet, S., European Journal of Neuroscience, 2005, 10.1111/j.1460-9568.2005.03932.x
Posttraumatic epilepsy: The roles of synaptic plasticity, Nita, D.A., Avramescu, S., Bazhenov, M., Timofeev, I., Neuroscientist, 2010, 10.1177/1073858409333545
Chronic Stress Induces Sex-Specific Functional and Morphological Alterations in Corticoaccumbal and Corticotegmental Pathways, , Biological Psychiatry, 2021, 10.1016/j.biopsych.2021.02.014
Callosal responses of fast-rhythmic-bursting neurons during slow oscillation in cats, Timofeev, I., Steriade, M., Nita, D.A., Cissé, Y., Neuroscience, 2007, 10.1016/j.neuroscience.2007.04.025
Effect of synaptic connectivity on long-range synchronization of fast cortical oscillations, Timofeev, I., Rulkov, N.F., Bazhenov, M., Journal of Neurophysiology, 2008, 10.1152/jn.90613.2008
Neocortical inhibitory activities and long-range afferents contribute to the synchronous onset of silent states of the neocortical slow oscillation, Timofeev, I., Chauvette, S., Lemieux, M., Journal of Neurophysiology, 2015, 10.1152/jn.00858.2013
Respiration organizes gamma synchrony in the prefronto-thalamic network, Igor Timofeev, Maxim Sheroziya, Sylvain Chauvette, Diellor Basha, Scientific Reports, 2023, 10.1038/s41598-023-35516-7
Role of thalamic and cortical neurons in augmenting responses and self- sustained activity: Dual intracellular recordings in vivo, Dürmüller, N., Grenier, F., Timofeev, I., Steriade, M., Journal of Neuroscience, 1998
Generators of ictal and interictal electroencephalograms associated with infantile spasms: intracellular studies of cortical and thalamic neurons, Timofeev, I., Steriade, M., International Review of Neurobiology, 2002
Corticothalamic operations through prevalent inhibition of thalamocortical neurons, Timofeev, I., Steriade, M., Thalamus and Related Systems, 2001, 10.1016/S1472-9288(01)00022-X
Neocortical focus: Experimental view, Soltani, S., Chauvette, S., Timofeev, I., International Review of Neurobiology, 2014, 10.1016/B978-0-12-418693-4.00002-9
Frequency-selective augmenting responses by short-term synaptic depression in cat neocortex, Sejnowski, T.J., Steriade, M., Grenier, F., Timofeev, I., Bazhenov, M., Houweling, A.R., Journal of Physiology, 2002, 10.1113/jphysiol.2001.012759
Short-term plasticity during intrathalamic augmenting responses in decorticated cats, Timofeev, I., Steriade, M., Journal of Neuroscience, 1997
Just a sound: A non-pharmacological treatment approach in epilepsy., Timofeev I, Cell reports. Medicine, 2021, 10.1016/j.xcrm.2021.100451
Cellular basis of transition between sleep and electrographic seizures,Bases cellulaires des transitions de l'état de sommeil aux paroxysmes épileptiformes, Timofeev, I., Amzica, F., Steriade, M., Medecine/Sciences, 2003
Detection of active and silent states in neocortical neurons from the field potential signal during slow-wave sleep, Volgushev, M., Timofeev, I., Chauvette, S., Mukovski, M., Cerebral Cortex, 2007, 10.1093/cercor/bhj157
The spindles: Are they still thalamic?, Chauvette, S., Timofeev, I., Sleep, 2013, 10.5665/sleep.2702
Sleep, oscillations, and epilepsy, Igor Timofeev, Jennifer Gelinas, Birgit Frauscher, Christophe Bernard, Epilepsia, 2023, 10.1111/epi.17664
Global control of sleep slow wave activity, Sylvain Chauvette, Igor Timofeev, Nature Neuroscience, 2020, 10.1038/s41593-020-0638-2
Neuronal activities during palatable food consumption in the reward system of binge-like eating female rats, , Physiology & Behavior, 2021, 10.1016/j.physbeh.2021.113604
Local origin of slow EEG waves during sleep., Timofeev, I., Zhurnal vyssheǐ nervnoǐ deiatelnosti imeni I P Pavlova, 2013, 10.7868/S0044467713010139
Contribution of intrinsic neuronal factors in the generation of cortically driven electrographic seizures, Steriade, M., Grenier, F., Timofeev, I., Journal of Neurophysiology, 2004, 10.1152/jn.00523.2003
Membrane bistability in thalamic reticular neurons during spindle oscillations, Steriade, M., Sejnowski, T.J., Bazhenov, M., Timofeev, I., Fuentealba, P., Journal of Neurophysiology, 2005, 10.1152/jn.00552.2004
Natural waking and sleep states: A view from inside neocortical neurons, Grenier, F., Timofeev, I., Steriade, M., Journal of Neurophysiology, 2001
Homeostatic Plasticity and Post-Traumatic Epileptogenesis, Sejnowski, T.J., Timofeev, I., Houweling, A.R., Bazhenov, M., Computational Neuroscience in Epilepsy, 2008, 10.1016/B978-012373649-9.50020-X
Brain states in freely behaving marmosets, Igor Timofeev, Josée Seigneur, Sylvain Chauvette, Olga Bukhtiyarova, Sleep, 2022, 10.1093/sleep/zsac106
EPSP depression following neocortical seizures in cat, Timofeev, I., Cissé, Y., Nita, D.A., Epilepsia, 2008, 10.1111/j.1528-1167.2007.01431.x
Synchronization of fast (30-40 Hz) spontaneous oscillations in intrathalamic and thalamocortical networks, Timofeev, I., Amzica, F., Contreras, D., Steriade, M., Journal of Neuroscience, 1996
Origin of slow cortical oscillations in deafferented cortical slabs, Steriade, M., Sejnowski, T.J., Bazhenov, M., Grenier, F., Timofeev, I., Cerebral Cortex, 2000
Properties of slow oscillation during slow-wave sleep and anesthesia in cats, Timofeev, I., Volgushev, M., Crochet, S., Chauvette, S., Journal of Neuroscience, 2011, 10.1523/JNEUROSCI.2339-11.2011
Synaptic plasticity in local cortical network in vivo and its modulation by the level of neuronal activity, Steriade, M., Timofeev, I., Cissé, Y., Fuentealba, P., Crochet, S., Cerebral Cortex, 2006, 10.1093/cercor/bhj008
Methodological standards and functional correlates of depth in vivo electrophysiological recordings in control rodents. A TASK1-WG3 report of the AES/ILAE Translational Task Force of the ILAE, Timofeev, I., Scott, R.C., Garcia-Cairasco, N., Williamson, A., Quilichini, P., Ikeda, A., de Curtis, M., Kahane, P., Galanopoulou, A.S., Worrell, G.A., Schevon, C.A., Hernan, A.E., Epilepsia, 2017, 10.1111/epi.13905
Fast (mainly 30-100 Hz) oscillations in the cat cerebellothalamic pathway and their synchronization with cortical potentials, Steriade, M., Timofeev, I., Journal of Physiology, 1997, 10.1111/j.1469-7793.1997.153bf.x
Projections from the nucleus accumbens shell to the ventral pallidum are involved in the control of sucrose intake in adult female rats, Igor Timofeev, Elena Timofeeva, Josée Seigneur, Geneviève Guèvremont, Sandrine Chometton, Brain Structure and Function, 2020, 10.1007/s00429-020-02161-z
Effect of synaptic connectivity on long-range synchronization of fast cortical oscillations (Journal of Neurophysiology (2008) 100, (1562-1575) DOI: 10.1152/jn.90613.2008), Timofeev, I., Rulkov, N.F., Bazhenov, M., Journal of Neurophysiology, 2008, 10.1152/jn.z9k-9187-corr.2008
The role of chloride-dependent inhibition and the activity of fast-spiking neurons during cortical spike-wave electrographic seizures, Steriade, M., Grenier, F., Timofeev, I., Neuroscience, 2002, 10.1016/S0306-4522(02)00300-7
Spike-wave complexes and fast components of cortically generated seizures. II. Extra- and intracellular patterns, Timofeev, I., Neckelmann, D., Amzica, F., Steriade, M., Journal of Neurophysiology, 1998, 10.1152/jn.1998.80.3.1456
Long-term synchronized electrophysiological and behavioral wireless monitoring of freely moving animals, Timofeev, I., Ftomov, S., Grand, L., Journal of Neuroscience Methods, 2013, 10.1016/j.jneumeth.2012.10.008
Sleep slow oscillation and plasticity, Chauvette, S., Timofeev, I., Current Opinion in Neurobiology, 2017, 10.1016/j.conb.2017.03.019
Synaptic responsiveness of cortical and thalamic neurones during various phases of slow sleep oscillation in cat, Steriade, M., Contreras, D., Timofeev, I., Journal of Physiology, 1996, 10.1113/jphysiol.1996.sp021489
Disfacilitation and active inhibition in the neocortex during the natural sleep-wake cycle: An intracellular study, Steriade, M., Grenier, F., Timofeev, I., Proceedings of the National Academy of Sciences of the United States of America, 2001, 10.1073/pnas.98.4.1924
Cellular and network models for intrathalamic augmenting responses during 10-Hz stimulation, Sejnowski, T.J., Steriade, M., Timofeev, I., Bazhenov, M., Journal of Neurophysiology, 1998, 10.1152/jn.1998.79.5.2730
Mechanisms of physiological and epileptic HFO generation, Lopes da Silva, F.H., Timofeev, I., Avoli, M., Bragin, A., Wendling, F., Menendez de la Prida, L., Jefferys, J.G.R., Progress in Neurobiology, 2012, 10.1016/j.pneurobio.2012.02.005
Experimental evidence and modeling studies support a synchronizing role for electrical coupling in the cat thalamic reticular neurons in vivo, Steriade, M., Sejnowski, T.J., Bazhenov, M., Timofeev, I., Crochet, S., Fuentealba, P., European Journal of Neuroscience, 2004, 10.1111/j.1460-9568.2004.03462.x
Oscillations in large-scale cortical networks: Map-based model, Bazhenov, M., Timofeev, I., Rulkov, N.F., Journal of Computational Neuroscience, 2004, 10.1023/B:JCNS.0000037683.55688.7e
Homeostatic synaptic plasticity can explain post-traumatic epileptogenesis in chronically isolated neocortex, Sejnowski, T.J., Steriade, M., Timofeev, I., Bazhenov, M., Houweling, A.R., Cerebral Cortex, 2005, 10.1093/cercor/bhh184
Differential Expression of DeltaFosB in Reward Processing Regions Between Binge Eating Prone and Resistant Female Rats, , Frontiers in Systems Neuroscience, 2020, 10.3389/fnsys.2020.562154
Sleep Oscillations in the Thalamocortical System Induce Long-Term Neuronal Plasticity, Timofeev, I., Seigneur, J., Chauvette, S., Neuron, 2012, 10.1016/j.neuron.2012.08.034
Dynamic properties of corticothalamic neurons and local cortical interneurons generating fast rhythmic (30-40 Hz) spike bursts, Grenier, F., Dürmüller, N., Timofeev, I., Steriade, M., Journal of Neurophysiology, 1998, 10.1152/jn.1998.79.1.483
Global intracellular slow-wave dynamics of the thalamocortical system, Timofeev, I., Sheroziya, M., Journal of Neuroscience, 2014, 10.1523/JNEUROSCI.4460-13.2014
Slow Wave Sleep Is a Promising Intervention Target for Alzheimer's Disease., Kastanenka KV, Bacskai BJ, Timofeev I, Gerashchenko D, Lee YF, Frontiers in neuroscience, 2020, 10.3389/fnins.2020.00705
Slow state transitions of sustained neural oscillations by activity-dependent modulation of intrinsic excitability., Sejnowski, T.J., Steriade, M., Timofeev, I., Bazhenov, M., Fröhlich, F., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, 10.1523/JNEUROSCI.5509-05.2006
Ionic and synaptic mechanisms of seizure generation and epileptogenesis, Bazhenov, M., Timofeev, I., Krishnan, G.P., González, O.C., Neurobiology of Disease, 2019, 10.1016/j.nbd.2019.104485
Spontaneous field potentials influence the activity of neocortical neurons during paroxysmal activities in vivo, Steriade, M., Crochet, S., Timofeev, I., Grenier, F., Neuroscience, 2003, 10.1016/S0306-4522(03)00101-5
Hyperexcitability of intact neurons underlies acute development of trauma-related electrographic seizures in cats in vivo, Timofeev, I., Steriade, M., Topolnik, L., European Journal of Neuroscience, 2003, 10.1046/j.1460-9568.2003.02742.x
Regulation of AMPA and NMDA receptor-mediated EPSPs in dendritic trees of thalamocortical cells, Timofeev, I., Kröger, H., Lajeunesse, F., Journal of Neurophysiology, 2013, 10.1152/jn.01090.2011
Synaptic strength modulation after cortical trauma: A role in epileptogenesis, Timofeev, I., Avramescu, S., Journal of Neuroscience, 2008, 10.1523/JNEUROSCI.0643-08.2008
Subcellular distribution of low-voltage activated T-Type Ca²⁺ channel subunits (Cav3.1 and Cav3.3) in reticular thalamic neurons of the cat, Timofeev, I., Ricketts, C., Sík, A., Kovács, K., Journal of Neuroscience Research, 2010, 10.1002/jnr.22200
In vivo models of cortical acquired epilepsy, Timofeev, I., Seigneur, J., Soltani, S., Chauvette, S., Journal of Neuroscience Methods, 2016, 10.1016/j.jneumeth.2015.08.030
Role of Spindle Oscillations across Lifespan in Health and Disease, Peyrache, A., Carrier, J., Timofeev, I., Seibt, J., Neural Plasticity, 2016, 10.1155/2016/8103439
Thalamocortical oscillations: Local control of EEG slow waves, Chauvette, S., Timofeev, I., Current Topics in Medicinal Chemistry, 2011, 10.2174/156802611797470376
Long-range correlation of the membrane potential in neocortical neurons during slow oscillation, Timofeev, I., Chauvette, S., Volgushev, M., Progress in Brain Research, 2011, 10.1016/B978-0-444-53839-0.00012-0
Neuronal plasticity in thalamocortical networks during sleep and waking oscillations, Timofeev, I., Steriade, M., Neuron, 2003, 10.1016/S0896-6273(03)00065-5
Low-frequency rhythms in the thalamus of intact-cortex and decorticated cats, Steriade, M., Timofeev, I., Journal of Neurophysiology, 1996, 10.1152/jn.1996.76.6.4152
Cellular mechanisms underlying intrathalamic augmenting responses of reticular and relay neurons, Steriade, M., Timofeev, I., Journal of Neurophysiology, 1998, 10.1152/jn.1998.79.5.2716
Synaptic responsiveness of neocortical neurons to callosal volleys during paroxysmal depolarizing shifts, Timofeev, I., Steriade, M., Crochet, S., Cissé, Y., Neuroscience, 2004, 10.1016/j.neuroscience.2003.11.003
Cellular Mechanisms of Thalamocortical Oscillations in the Sleeping Brain, , Neuronal Oscillations of Wakefulness and Sleep, 2020, 10.1007/978-1-0716-0653-7_5
Neocortical seizures: Initiation, development and cessation, Steriade, M., Timofeev, I., Neuroscience, 2004, 10.1016/j.neuroscience.2003.08.051
Leading role of thalamic over cortical neurons during postinhibitory rebound excitation, Steriade, M., Timofeev, I., Grenier, F., Proceedings of the National Academy of Sciences of the United States of America, 1998, 10.1073/pnas.95.23.13929
Injury induced epileptogenesis: Contribution of active inhibition, disfacilitation and deafferentation to seizure induction in thalamocortical system, Timofeev, I., Inhibitory Synaptic Plasticity, 2011, 10.1007/978-1-4419-6978-1_8
Changes in long-range connectivity and neuronal reorganization in partial cortical deafferentation model of epileptogenesis, Timofeev, I., Grand, L., Lajeunesse, F., Kuśmierczak, M., Neuroscience, 2015, 10.1016/j.neuroscience.2014.09.079
Maintenance and termination of neocortical oscillations by dynamic modulation of intrinsic and synaptic excitability, Sejnowski, T.J., Timofeev, I., Bazhenov, M., Fröhlich, F., Thalamus and Related Systems, 2005, 10.1017/S1472928807000155
Prolonged hyperpolarizing potentials precede spindle oscillations in the thalamic reticular nucleus, Steriade, M., Timofeev, I., Fuentealba, P., Proceedings of the National Academy of Sciences of the United States of America, 2004, 10.1073/pnas.0402761101
Sleep–Wake Cycle in Young and Older Mice, Timofeev, I., Carrier, J., Seigneur, J., Dubé, J., Lina, J.-M., Bukhtiyarova, O., Chauvette, S., Soltani, S., Frontiers in Systems Neuroscience, 2019, 10.3389/fnsys.2019.00051
The impact of cortical deafferentation on the neocortical slow oscillation, Timofeev, I., Bazhenov, M., Lonjers, P., Chen, J.-Y., Lemieux, M., Journal of Neuroscience, 2014, 10.1523/JNEUROSCI.1156-13.2014
Sleep-Wake and Cortical Synaptic Plasticity, Chauvette, S., Timofeev, I., Handbook of Behavioral Neuroscience, 2019, 10.1016/B978-0-12-813743-7.00029-3
Modeling of age-dependent epileptogenesis by differential homeostatic synaptic scaling, Bazhenov, M., Sejnowski, T., Timofeev, I., Chauvette, S., Krishnan, G.P., González, O.C., Journal of Neuroscience, 2015, 10.1523/JNEUROSCI.5038-14.2015
Neuronal mechanisms mediating the variability of somatosensory evoked potentials during sleep oscillations in cats, Timofeev, I., Rosanova, M., Journal of Physiology, 2005, 10.1113/jphysiol.2004.071381
Analysis of morphological features of thalamocortical neurons from the ventroposterolateral nucleus of the cat, Timofeev, I., Kröger, H., Kovács, K., Ferecskó, A.S., Zomorrodi, R., Journal of Comparative Neurology, 2010, 10.1002/cne.22413
Moderate cortical cooling eliminates thalamocortical silent states during slow oscillation, Timofeev, I., Sheroziya, M., Journal of Neuroscience, 2015, 10.1523/JNEUROSCI.1359-15.2015
Waking-sleep modulation of paroxysmal activities induced by partial cortical deafferentation, Steriade, M., Timofeev, I., Cissé, Y., Nita, D.A., Cerebral Cortex, 2007, 10.1093/cercor/bhj145
Neocortical post-traumatic epileptogenesis is associated with loss of GABAergic neurons., Timofeev, I., Nita, D.A., Avramescu, S., Journal of neurotrauma, 2009, 10.1089/neu.2008.0739
Thalamic short-term plasticity and its impact on the neocortex, Steriade, M., Timofeev, I., Grenier, F., Thalamus and Related Systems, 2002, 10.1016/S1472-9288(02)00006-7
Sleep, Anesthesia, and Plasticity, Chauvette, S., Timofeev, I., Neuron, 2018, 10.1016/j.neuron.2018.03.013
Neuronal Oscillations in the Thalamocortical System During Sleeping and Waking States, Timofeev, I., Sleep and Brain Activity, 2012, 10.1016/B978-0-12-384995-3.00001-0
Self-sustained rhythmic activity in the thalamic reticular nucleus mediated by depolarizing GABA(A) receptor potentials, Sejnowski, T.J., Steriade, M., Timofeev, I., Bazhenov, M., Nature Neuroscience, 1999, 10.1038/5729
Erratum: Precise long-range synchronization of activity and silence in neocortical neurons during slow-wave sleep (Journal of Neuroscience (May 24, 2006) (5665-5672)), Timofeev, I., Mukovski, M., Chauvette, S., Volgushev, M., Journal of Neuroscience, 2006
Cellular and network mechanisms of electrographic seizures, Sejnowski, T.J., Fröhlich, F., Timofeev, I., Bazhenov, M., Drug Discovery Today: Disease Models, 2008, 10.1016/j.ddmod.2008.07.005
The reuniens nucleus of the thalamus facilitates hippocampo-cortical dialogue during sleep, Igor Timofeev, Maryam Ghorbani, Sylvain Chauvette, Elian Proulx, Amirmohammad Azarmehri, Diellor Basha, eLife, 2025, 10.7554/eLife.90826
Neuronal Activity During the Sleep-Wake Cycle, Chauvette, S., Timofeev, I., Handbook of Behavioral Neuroscience, 2019, 10.1016/B978-0-12-813743-7.00001-3
Electrophysiological properties and input-output organization of callosal neurons in cat association cortex, Steriade, M., Timofeev, I., Grenier, F., Cissé, Y., Journal of Neurophysiology, 2003, 10.1152/jn.0871.2002
Selective amplification of neocortical neuronal output by fast prepotentials in vivo, Steriade, M., Timofeev, I., Fuentealba, P., Crochet, S., Cerebral Cortex, 2004, 10.1093/cercor/bhh071
Sleep slow oscillation and inhibition, Igor Timofeev, The Journal of Physiology, 2020, 10.1113/JP280146
Spike-wave complexes and fast components of cortically generated seizures. IV. Paroxysmal fast runs cortical and thalamic neurons, Steriade, M., Grenier, F., Timofeev, I., Journal of Neurophysiology, 1998, 10.1152/jn.1998.80.3.1495
Synaptic enhancement induced through callosal pathways in cat association cortex, Steriade, M., Timofeev, I., Crochet, S., Cissé, Y., Journal of Neurophysiology, 2004, 10.1152/jn.00537.2004
Increased propensity to seizures after chronic cortical deafferentation in vivo, Steriade, M., Timofeev, I., Cissé, Y., Nita, D.A., Journal of Neurophysiology, 2006, 10.1152/jn.00742.2005
Differential expression of deltaFosB in reward processing regions between binge eating prone and resistant female rats, Igor Timofeev, Elena Timofeeva, Genevieve Guèvremont, Juliane Calvez, Sandrine Chometton, Richard Quansah Amissah, 2019, 10.1101/821355
Model of thalamocortical slow-wave sleep oscillations and transitions to activated states, Sejnowski, T.J., Steriade, M., Timofeev, I., Bazhenov, M., Journal of Neuroscience, 2002
Role of network dynamics in shaping spike timing reliability, Timofeev, I., Fellous, J.-M., Rulkov, N.F., Bazhenov, M., Physical Review E - Statistical, Nonlinear, and Soft Matter Physics, 2005, 10.1103/PhysRevE.72.041903

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Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2020/06

Rémi Pellegrinato - Doctorat - En cours
Ali Reza Danesh - Maîtrise avec mémoire - 2021/05
Diellor Basha - Doctorat - 2024/09

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Neurobiologie — Neurosciences

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