Guy Poirier

Poly(ADP-ribose) polymerase activity in mouse cells which exhibit temperature-sensitive DNA synthesis., , Biochimica et biophysica acta, 1981, 10.1016/0005-2787(81)90162-3

Comparative inhibitory effects of 3-quinuclidinyl benzilate (QNB) and atropine on amylase release from rat pancreas., , British journal of pharmacology, 1977, 10.1111/j.1476-5381.1977.tb09745.x

Nonisotopic methods for determination of poly(ADP-ribose) levels and detection of poly(ADP-ribose) polymerase., , Current protocols in cell biology, 2004, 10.1002/0471143030.cb1807s21

ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion., , Cell reports, 2014, 10.1016/j.celrep.2014.08.036

Adenosine diphosphoribosylation of certain basic chromosomal proteins in isolated trout testis nuclei., , European journal of biochemistry, 1977, 10.1111/j.1432-1033.1977.tb11635.x

Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death., , Nature medicine, 2011, 10.1038/nm.2387

Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis., , Proceedings of the National Academy of Sciences of the United States of America, 1996, 10.1073/pnas.93.16.8395

Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats., , The Journal of nutrition, 2002, 10.1093/jn/132.1.115

Determination of Poly(ADP-Ribose) polymerase activation and cleavage during cell death, , Cell death. The role of PARP, 2000

Effect of early weaning of the neonatal rat on pancreatic acinar cell responsiveness to urecholine., , Digestion, 1978, 10.1159/000198126

Genomic location of the human RNA polymerase II general machinery: evidence for a role of TFIIF and Rpb7 at both early and late stages of transcription., , The Biochemical journal, 2008, 10.1042/BJ20070751

Immunological determination and size characterization of poly(ADP-ribose) synthesized in vitro and in vivo., , Biochimica et biophysica acta, 1999, 10.1016/s0304-4165(99)00054-9

Expression in E. coli of the catalytic domain of rat poly(ADP-ribose)polymerase., , FEBS letters, 1990, 10.1016/0014-5793(90)80770-j

Temporal changes in chromatin, intracellular calcium, and poly(ADP-ribose) polymerase during Sindbis virus-induced apoptosis of neuroblastoma cells., , Journal of virology, 1996, 10.1128/JVI.70.4.2215-2220.1996

Liver poly(ADP-ribose)polymerase is resistant to cleavage by caspases., , Biochemical and biophysical research communications, 1999, 10.1006/bbrc.1999.0313

Identification of mitofusin 1 and complement component 1q subcomponent-binding protein as mitochondrial targets in systemic lupus erythematosus., , Arthritis & rheumatology (Hoboken, N.J.), 2022, 10.1002/art.42082

Comparative proteome analysis of human epithelial ovarian cancer., , Proteome science, 2007, 10.1186/1477-5956-5-16

The effect of poly(ADP-ribosyl)ation on native and H1-depleted chromatin. A role of poly(ADP-ribosyl)ation on core nucleosome structure., , The Journal of biological chemistry, 1989

Specific cleavage of the large subunit of replication factor C in apoptosis is mediated by CPP32-like protease., , Biochemical and biophysical research communications, 1997, 10.1006/bbrc.1997.6456

Cloning of rodent cDNA coding the poly(ADP-ribose) polymerase catalytic domain and analysis of mRNA levels during the cell cycle., , Biochemistry and cell biology = Biochimie et biologie cellulaire, 1989, 10.1139/o89-097

Hydrofluoric Acid-Based Derivatization Strategy To Profile PARP-1 ADP-Ribosylation by LC-MS/MS., , Journal of proteome research, 2018, 10.1021/acs.jproteome.8b00146

Bioinformatics standards for mass spectrometry, , Current Proteomics: the journal for current and in-depth reviews on proteomics, 2006

Modulation of pancreatic muscarinic receptors by weaning., , Life sciences, 1982, 10.1016/0024-3205(82)90506-9

Quantitative proteomics and dynamic imaging reveal that G3BP-mediated stress granule assembly is poly(ADP-ribose)-dependent following exposure to MNNG-induced DNA alkylation., , Journal of cell science, 2012, 10.1242/jcs.106963

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor., , Science (New York, N.Y.), 2002, 10.1126/science.1072221

Overexpression of bcl-2 or bcl-XL fails to inhibit apoptosis mediated by a novel retinoid., , Oncology research, 1998

Poly(ADP-ribosyl)ation of chromatin: kinetics of relaxation and its effect on chromatin solubility., , Canadian journal of biochemistry and cell biology = Revue canadienne de biochimie et biologie cellulaire, 1985, 10.1139/o85-096

Association of poly(ADP-ribose) polymerase with the nuclear matrix: the role of intermolecular disulfide bond formation, RNA retention, and cell type., , Experimental cell research, 1991, 10.1016/0014-4827(91)90072-3

Rapid assay of poly(ADP-ribose) glycohydrolase., , Biochemistry and cell biology = Biochimie et biologie cellulaire, 1987, 10.1139/o87-088

High-performance electrophoresis chromatography., , Methods in molecular biology (Clifton, N.J.), 1996, 10.1385/0-89603-336-8:371

NAD(+)-dependent repair of damaged DNA by human cell extracts., , The Journal of biological chemistry, 1993

Polycomb repressive complex 2 contributes to DNA double-strand break repair., , Cell cycle (Georgetown, Tex.), 2013, 10.4161/cc.25795

Poly(ADP-ribosyl)ated chromatin domains: access granted., , Journal of cell science, 2004, 10.1242/jcs.01080

Tumor promoter phorbol-12-myristate-13-acetate induces poly ADP-ribosylation in human monocytes., , Biochemical and biophysical research communications, 1985, 10.1016/0006-291x(85)90314-6

Modulation of caspase-3 activity by zinc ions and by the cell redox state., , Experimental cell research, 2001, 10.1006/excr.2001.5222

Characterization of antibodies specific for the caspase cleavage site on poly(ADP-ribose) polymerase: specific detection of apoptotic fragments and mapping of the necrotic fragments of poly(ADP-ribose) polymerase., , Biochemistry and cell biology = Biochimie et biologie cellulaire, 1997

ADP-ribosylation Reactions, , 1992

Isolation of genomic DNA from the earthworm species Eisenia fetida., , Molecular and cellular biochemistry, 1995, 10.1007/BF00928909

Platelets release pathogenic serotonin and return to circulation after immune complex-mediated sequestration., , Proceedings of the National Academy of Sciences of the United States of America, 2018, 10.1073/pnas.1720553115

Poly(ADP-ribosylation) and apoptosis., , Molecular and cellular biochemistry, 1999, 10.1023/a:1006962716377

Transcription. Gene expression needs a break to unwind before carrying on., , Science (New York, N.Y.), 2006, 10.1126/science.1129808

Human papillomavirus E1 helicase interacts with the WD repeat protein p80 to promote maintenance of the viral genome in keratinocytes., , Journal of virology, 2008, 10.1128/JVI.01405-07

Proteomic characterization of mouse cytosolic and membrane prostate fractions: high levels of free SUMO peptides are androgen-regulated., , Journal of proteome research, 2008, 10.1021/pr8002497

A conserved initiator element on the mammalian poly(ADP-ribose) polymerase-1 promoters, in combination with flanking core elements, is necessary to obtain high transcriptional activity., , Biochimica et biophysica acta, 2004, 10.1016/j.bbaexp.2004.04.003

Involvement of caspase-dependent activation of cytosolic phospholipase A2 in tumor necrosis factor-induced apoptosis., , Proceedings of the National Academy of Sciences of the United States of America, 1997, 10.1073/pnas.94.10.5073

Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis., , The Journal of biological chemistry, 1999, 10.1074/jbc.274.7.4335

Nuclear factor 1 interferes with Sp1 binding through a composite element on the rat poly(ADP-ribose) polymerase promoter to modulate its activity in vitro., , The Journal of biological chemistry, 2001, 10.1074/jbc.M010360200

Non-histone chromosomal protein acceptors for poly(ADP)-ribose in phorbol-12-myristate-13-acetate treated mouse embryo fibroblasts (C3H10T1/2)., , Carcinogenesis, 1985, 10.1093/carcin/6.10.1489

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase., , Cell, 1995, 10.1016/0092-8674(95)90541-3

Poly(ADP-ribose) accessibility to poly(ADP-ribose) glycohydrolase activity on poly(ADP-ribosyl)ated nucleosomal proteins., , Biochemistry and cell biology = Biochimie et biologie cellulaire, 1986, 10.1139/o86-023

Experimental and bioinformatic approaches for interrogating protein-protein interactions to determine protein function., , Journal of molecular endocrinology, 2005, 10.1677/jme.1.01693

Selective and sensitive quantification of the cytochrome P450 3A4 protein in human liver homogenates through multiple reaction monitoring mass spectrometry., , Proteomics, 2016, 10.1002/pmic.201500386

Poly(ADP-ribosyl)ation of polynucleosomes causes relaxation of chromatin structure., , Proceedings of the National Academy of Sciences of the United States of America, 1982, 10.1073/pnas.79.11.3423

Proteomic and genomic analyses of antimony resistant Leishmania infantum mutant., , PloS one, 2013, 10.1371/journal.pone.0081899

Emerging roles of eraser enzymes in the dynamic control of protein ADP-ribosylation., , Nature communications, 2019, 10.1038/s41467-019-08859-x

The human UGT1A3 enzyme conjugates norursodeoxycholic acid into a C23-ester glucuronide in the liver., , The Journal of biological chemistry, 2010, 10.1074/jbc.M109.073908

Characterization and purification of a calcium-sensitive ATP diphosphohydrolase from pig pancreas., , The Journal of biological chemistry, 1980

Comparative study of DNA adducts levels in white sucker fish (Catostomus commersoni) from the basin of the St. Lawrence River (Canada)., , Molecular and cellular biochemistry, 1995, 10.1007/BF00928150

Expression in Escherichia coli of the 36 kDa domain of poly(ADP-ribose) polymerase and investigation of its DNA binding properties., , Biochimica et biophysica acta, 1993, 10.1016/0167-4838(93)90277-x

PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery., , Journal of cellular biochemistry, 2007, 10.1002/jcb.21051

Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis., , Cancer research, 1993

Aurora-A phosphorylates splicing factors and regulates alternative splicing, Claude Prigent, Erwan Watrin, Juan Valcárcel, Guy G. Poirier, Agnès Mereau, Justine Cailloce, Thibault Courtheoux, Estefania Mancini, Malgorzata Ewa Rogalska, Jean-Philippe Gagné, Olivia Gavard, Arun Prasath Damodaran, 2020, 10.1101/2020.11.04.368498

A novel approach to denoising ion trap tandem mass spectra., , Proteome science, 2009, 10.1186/1477-5956-7-9

DNA base excision repair of 5-hydroxymethyl-2'-deoxyuridine stimulates poly(ADP-ribose) synthesis in Chinese hamster cells., , Carcinogenesis, 1995, 10.1093/carcin/16.5.1173

Affinity-based assays for the identification and quantitative evaluation of noncovalent poly(ADP-ribose)-binding proteins., , Methods in molecular biology (Clifton, N.J.), 2011, 10.1007/978-1-61779-270-0_7

DrosophiladTBCE recruits tubulin around chromatin to promote mitotic spindle assembly, Régis Giet, Christelle Benaud, Laurent Richard-Parpaillon, Romain Gibeaux, Denis Chrétien, Guy G. Poirier, Jean-Philippe Gagné, Aude Pascal, Emmanuel Gallaud, Mathieu Métivier, 2020, 10.1101/2020.01.21.912428

Alteration of the nucleolar localization of poly(ADP-ribose) polymerase upon treatment with transcription inhibitors., , Experimental cell research, 1996, 10.1006/excr.1996.0259

Quantitative proteomics profiling of the poly(ADP-ribose)-related response to genotoxic stress., , Nucleic acids research, 2012, 10.1093/nar/gks486

Characterization of the necrotic cleavage of poly(ADP-ribose) polymerase (PARP-1): implication of lysosomal proteases., , Cell death and differentiation, 2001, 10.1038/sj.cdd.4400851

Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples., , Journal of proteome research, 2011, 10.1021/pr100990s

Immunodot blot method for the detection of poly(ADP-ribose) synthesized in vitro and in vivo., , Analytical biochemistry, 1998, 10.1006/abio.1998.2664

Relative affinities of poly(ADP-ribose) polymerase and DNA-dependent protein kinase for DNA strand interruptions., , Biochimica et biophysica acta, 1999, 10.1016/s0167-4838(98)00278-7

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage., , Proceedings of the National Academy of Sciences of the United States of America, 2011, 10.1073/pnas.1108799108

Rearrangements of the nucleosome structure in chromatin by poly(ADP-ribose)., , Biochimica et biophysica acta, 1992, 10.1016/0167-4838(92)90163-8

Analysis of poly(ADP-ribose) glycohydrolase activity in nuclear extracts from mammalian cells., , Biochimica et biophysica acta, 1997, 10.1016/s0167-4838(96)00188-4

Binding capacity of various fibre to pesticide residues under simulated gastrointestinal conditions., , Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1999, 10.1016/s0278-6915(99)00110-6

Enzymological properties of poly(ADP-ribose)polymerase: characterization of automodification sites and NADase activity., , Biochimica et biophysica acta, 1991, 10.1016/0167-4838(91)99007-f

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death., , Proceedings of the National Academy of Sciences of the United States of America, 2006, 10.1073/pnas.0606528103

A nuclear factor other than Sp1 binds the GC-rich promoter of the gene encoding rat poly(ADP-ribose) polymerase in vitro., , Biochemistry and cell biology = Biochimie et biologie cellulaire, 1997

LUCA-15-encoded sequence variants regulate CD95-mediated apoptosis., , Oncogene, 2000, 10.1038/sj.onc.1203720

6-Aminonicotinamide sensitizes human tumor cell lines to cisplatin., , Clinical cancer research : an official journal of the American Association for Cancer Research, 1998

Dynamic relocation of poly(ADP-ribose) glycohydrolase isoforms during radiation-induced DNA damage., , Biochimica et biophysica acta, 2006, 10.1016/j.bbamcr.2005.11.015

Stimulation of adenosine 3',5'-cyclic monophosphate accumulation in anterior pituitary gland in vitro by purified growth hormone-releasing hormone., , Transactions of the Association of American Physicians, 1973

Preferential perinuclear localization of poly(ADP-ribose) glycohydrolase., , Experimental cell research, 1999, 10.1006/excr.1999.4594

Poly(ADP-ribosyl)ation reactions and modulation of chromatin structure, , DNA repair mechanisms and their biological implications in mammalian cells, 1990

Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7., , The Journal of biological chemistry, 1999, 10.1074/jbc.274.40.28379

Failure to degrade poly(ADP-ribose) causes increased sensitivity to cytotoxicity and early embryonic lethality., , Proceedings of the National Academy of Sciences of the United States of America, 2004, 10.1073/pnas.0406182101

Low hepatic ethoxyresorufin-O-deethylase activity correlates with high organochlorine concentrations in Atlantic tomcod from the Canadian east coast., , Environmental toxicology and chemistry, 2005, 10.1897/05-048r.1

The role of poly(ADP-ribose) metabolism in response to active oxygen cytotoxicity., , Biochimica et biophysica acta, 1994, 10.1016/0167-4889(94)90243-7

Delayed weaning and denial of solid food nibbling upon pancreatic acinar cell responsiveness to urecholine in neonatal rats., , Digestion, 1978, 10.1159/000198188

Germline mutations in BAP1 impair its function in DNA double-strand break repair., , Cancer research, 2014, 10.1158/0008-5472.CAN-13-3109

Rapid removal of nonspecific background in silver-stained polyacrylamide gel., , Analytical biochemistry, 1995, 10.1006/abio.1995.9947

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes., , Nucleic acids research, 2008, 10.1093/nar/gkn771

Modulation of chromatin structure by poly(ADP-ribosyl)ation, , ADP-ribose transfer reactions: mechanisms and biological significance, 1989

A Phase I Clinical Trial of the Poly(ADP-ribose) Polymerase Inhibitor Veliparib and Weekly Topotecan in Patients with Solid Tumors., , Clinical cancer research : an official journal of the American Association for Cancer Research, 2018, 10.1158/1078-0432.CCR-17-1590

Glycol ethers induce death and necrosis in human leukemia cells., , Biochemistry and cell biology = Biochimie et biologie cellulaire, 1997

Tumor promoter phorbol-12-myristate-13-acetate induces poly(ADP)-ribosylation in fibroblasts., , The EMBO journal, 1985

Identification of Streptomyces coelicolor proteins that are differentially expressed in the presence of plant material., , Applied and environmental microbiology, 2003, 10.1128/AEM.69.4.1884-1889.2003

Inhibition of ICE-related proteases (caspases) and nuclear apoptosis by phenylarsine oxide., , Experimental cell research, 1997, 10.1006/excr.1996.3459

An SNP in an ultraconserved regulatory element affects Dlx5/Dlx6 regulation in the forebrain., , Development (Cambridge, England), 2010, 10.1242/dev.051052

Reconstitution of an in vitro poly(ADP)-ribose turnover system, , ADP-ribose transfer reactions: mechanisms and biological significance, 1989

Poly(ADP-ribose) turnover in quail myoblast cells: relation between the polymer level and its catabolism by glycohydrolase., , Molecular and cellular biochemistry, 1999

Identification of sequence-specific DNA-binding proteins by southwestern blotting., , Methods in molecular biology (Clifton, N.J.), 2001, 10.1385/1-59259-208-2:255

A key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest development., , PloS one, 2011, 10.1371/journal.pone.0015834

Gain-of-function of poly(ADP-ribose) polymerase-1 upon cleavage by apoptotic proteases: implications for apoptosis., , Journal of cell science, 2001

Visualization of poly(ADP-ribose) synthetase associated with polynucleosomes by immunoelectron microscopy., , Biochimica et biophysica acta, 1986, 10.1016/0167-4889(86)90239-9

In-situ analysis of cellular poly(ADP-ribose) production in scrapie-infected mouse neuroblastoma cells., , The Histochemical journal, 2002, 10.1023/a:1023398130945

Muscarinic receptors of the pancreas: a correlation between displacement of (3 H)-quinuclidinyl benzilate binding and amylase secretion., , Pharmacology, 1979, 10.1159/000137262

Effect of hyperthermia on poly(adenosine diphosphate-ribose) glycohydrolase., , Cancer research, 1988

Interaction of DNA-dependent protein kinase and poly(ADP-ribose) polymerase with radiation-induced DNA strand breaks., , Radiation research, 1997

Hyper(ADP-ribosyl)ation of histone H1., , Canadian journal of biochemistry, 1982, 10.1139/o82-139

Poly(ADP-ribose) polymerase-1 antagonizes DNA resection at double-strand breaks., , Nature communications, 2019, 10.1038/s41467-019-10741-9

Crystallographic and biochemical analysis of the mouse poly(ADP-ribose) glycohydrolase., , PloS one, 2014, 10.1371/journal.pone.0086010

Molecular Cloning of the rat poly(ADP-ribose)polymerase gene and preliminary characterization of its promoter and 5'-flanking region, , ADP-ribosylation Reactions, 1992

Purification of poly(ADP-ribose) glycohydrolase and detection of its isoforms by a zymogram following one- or two-dimensional electrophoresis., , Analytical biochemistry, 1994, 10.1006/abio.1994.1177

Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination., , Genes & development, 2019, 10.1101/gad.315978.118

Correlation between endogenous nucleosomal hyper(ADP-ribosyl)ation of histone H1 and the induction of chromatin relaxation., , The EMBO journal, 1983

Transcriptional regulation of the rat poly(ADP-ribose) polymerase gene by Sp1., , European journal of biochemistry, 1997, 10.1111/j.1432-1033.1997.0342a.x

Proteomic analysis of enriched lysosomes at early phase of camptothecin-induced apoptosis in human U-937 cells., , Journal of proteomics, 2009, 10.1016/j.jprot.2009.04.003

Stimulation of poly(ADP-ribose) synthesis by free radicals in C3H10T1/2 cells: relationship with NAD metabolism and DNA breakage., , Biochemistry and cell biology = Biochimie et biologie cellulaire, 1990, 10.1139/o90-085

Roles of Rad51 paralogs for promoting homologous recombination in Leishmania infantum., , Nucleic acids research, 2015, 10.1093/nar/gkv118

PARP-3 and APLF function together to accelerate nonhomologous end-joining., , Molecular cell, 2011, 10.1016/j.molcel.2010.12.006

Monoclonal antibodies against poly(ADP- ribose) polymerase. Epitope mapping, inhibition of activity and interspecies immunoreactivity, , ADP-ribose transfer reactions: mechanisms and biological significance, 1989

Purification of the death substrate poly(ADP-ribose) polymerase., , Analytical biochemistry, 1997, 10.1006/abio.1997.2153

Separation of poly(ADP-ribosylated) nuclear proteins by polyacrylamide gel electrophoresis at acidic pH and low temperature., , Analytical biochemistry, 1981, 10.1016/0003-2697(81)90489-9

Detection of poly(ADP-ribose) polymerase and its apoptosis-specific fragment by a nonisotopic activity-western blot technique., , Analytical biochemistry, 1995, 10.1006/abio.1995.0016

PARP-1 modulation of mTOR signaling in response to a DNA alkylating agent., , PloS one, 2012, 10.1371/journal.pone.0047978

The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase., , Journal of virology, 2021, 10.1128/JVI.01969-20

Aurora kinase A localises to mitochondria to control organelle dynamics and energy production., , eLife, 2018, 10.7554/eLife.38111

Poly(ADP-ribose) polymerase-dependent energy depletion occurs through inhibition of glycolysis., , Proceedings of the National Academy of Sciences of the United States of America, 2014, 10.1073/pnas.1405158111

Proteomic investigation of phosphorylation sites in poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase., , Journal of proteome research, 2009, 10.1021/pr800810n

An affinity matrix for the purification of poly(ADP-ribose) glycohydrolase., , Nucleic acids research, 1990, 10.1093/nar/18.16.4691

Ethoxyresorufin O-deethylase (EROD) activity in placental tissue from Inuit women exposed to organochlorines through the arctic food chain, , Organohalogen Compounds, 1996

High Performance Electrophoresis Chromatography, , The protein protocols handbook, 1996

PARP-1, a determinant of cell survival in response to DNA damage., , Experimental hematology, 2003, 10.1016/s0301-472x(03)00083-3

Assessment of PARP-3 distribution in tissues of cynomolgous monkeys., , The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2009, 10.1369/jhc.2009.953380

Proteolysis of poly(ADP-ribose) polymerase by caspase 3: kinetics of cleavage of mono(ADP-ribosyl)ated and DNA-bound substrates., , Radiation research, 1998

Identification of a 116 kDa protein able to bind 1,3-bis(2-chloroethyl)-1-nitrosourea-damaged DNA as poly(ADP-ribose) polymerase., , Mutation research, 1996, 10.1016/0921-8777(95)00030-5

Overexpression of human poly(ADP-ribose) polymerase in transfected hamster cells leads to increased poly(ADP-ribosyl)ation and cellular sensitization to gamma irradiation., , European journal of biochemistry, 1997, 10.1111/j.1432-1033.1997.00015.x

Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution., , Proceedings of the National Academy of Sciences of the United States of America, 1995, 10.1073/pnas.92.20.9042

PARP degradation in apoptotic Syrian hamster embryo (SHE) cells compared to HL60 cell line., , Biochimie, 2000, 10.1016/s0300-9084(00)01194-9

Cytochrome P450 CYP1A1 enzyme activity and DNA adducts in placenta of women environmentally exposed to organochlorines., , Environmental research, 1999, 10.1006/enrs.1998.3920

Proteomics reveals a switch in CDK1-associated proteins upon M-phase exit during the Xenopus laevis oocyte to embryo transition., , The international journal of biochemistry & cell biology, 2012, 10.1016/j.biocel.2011.09.003

Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases., , The Journal of biological chemistry, 1996, 10.1074/jbc.271.9.4573

Excretion of volatile nitrosamines in a rural population in relation to food and drinking water consumption., , Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2000, 10.1016/s0278-6915(00)00089-2

32P-postlabeling determination of DNA adducts in the earthworm Lumbricus terrestris exposed to PAH-contaminated soils., , Bulletin of environmental contamination and toxicology, 1995, 10.1007/BF00206095

Nucleosomal poly(ADP-ribose) polymerase: properties and relaxation of the chromatin structure., , Princess Takamatsu symposia., 1983

ADP-ribosyltransferases, an update on function and nomenclature., , The FEBS journal, 2021, 10.1111/febs.16142

Isolation, purification and partial characterization of chloragocytes from the earthworm species Lumbricus terrestris., , Molecular and cellular biochemistry, 1998, 10.1023/a:1006882207581

Alteration of poly(ADP-ribose) glycohydrolase nucleocytoplasmic shuttling characteristics upon cleavage by apoptotic proteases., , Biology of the cell, 2003, 10.1016/j.biolcel.2003.10.003

Poly(ADP-ribose) drives pathologic α-synuclein neurodegeneration in Parkinson's disease., , Science (New York, N.Y.), 2018, 10.1126/science.aat8407

Quality assessment of peptide tandem mass spectra., , BMC bioinformatics, 2008, 10.1186/1471-2105-9-S6-S13

Targeting poly(ADP-ribosyl)ation: a promising approach in cancer therapy., , Trends in molecular medicine, 2005, 10.1016/j.molmed.2005.08.003

Maturation of muscarinic agonist receptors in rat developing pancreas and its relation to maximal enzyme secretion., , Life sciences, 1981, 10.1016/0024-3205(81)90537-3

Role of an acidic compartment in tumor-necrosis-factor-alpha-induced production of ceramide, activation of caspase-3 and apoptosis., , European journal of biochemistry, 1998, 10.1046/j.1432-1327.1998.2510295.x

Assessment of PARP-1 Distribution in Tissues of Cynomolgus Monkeys., , The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2020, 10.1369/0022155420926022

Fanconi anemia C protein acts at a switch between apoptosis and necrosis in mitomycin C-induced cell death., , Experimental cell research, 1999, 10.1006/excr.1998.4316

Adenohypophyseal secretory granules. I. Their phosphorylation and association with protein kinase., , The Journal of biological chemistry, 1971

Purification of plasma membranes from rat pancreas: a rapid method., , Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1977, 10.3181/00379727-155-39799

A proteomic approach to the identification of heterogeneous nuclear ribonucleoproteins as a new family of poly(ADP-ribose)-binding proteins., , The Biochemical journal, 2003, 10.1042/BJ20021675

Bcl-2 and adenovirus E1B 19 kDA protein prevent E1A-induced processing of CPP32 and cleavage of poly(ADP-ribose) polymerase., , Oncogene, 1996

Poly(ADP-ribose)polymerase: a novel finger protein., , Nucleic acids research, 1989, 10.1093/nar/17.12.4689

CARM1 regulates replication fork speed and stress response by stimulating PARP1., , Molecular cell, 2021, 10.1016/j.molcel.2020.12.010

Modulation of rat pancreatic muscarinic cholinergic receptors by caerulein., , Biochemical pharmacology, 1985, 10.1016/0006-2952(85)90609-4

Amino acid substitutions that specifically impair the transcriptional activity of papillomavirus E2 affect binding to the long isoform of Brd4., , Virology, 2007, 10.1016/j.virol.2006.08.035

Complete inhibition of poly(ADP-ribose) polymerase activity prevents the recovery of C3H10T1/2 cells from oxidative stress., , Biochimica et biophysica acta, 1996, 10.1016/0167-4889(96)00004-3

Direct Phosphorylation of SRC Homology 3 Domains by Tyrosine Kinase Receptors Disassembles Ligand-Induced Signaling Networks., , Molecular cell, 2018, 10.1016/j.molcel.2018.05.013

A convenient method for the ATPase assay., , Analytical biochemistry, 1978, 10.1016/0003-2697(78)90277-4

Comparative proteomics analyses reveal a potential biomarker for the detection of vancomycin-intermediate Staphylococcus aureus strains., , Journal of proteome research, 2007, 10.1021/pr070521m

The baculovirus p35 protein inhibits Fas- and tumor necrosis factor-induced apoptosis., , The Journal of biological chemistry, 1995, 10.1074/jbc.270.28.16526

Environmental exposure to polychlorinated biphenyls and placental CYP1A1 activity in Inuit women from northern Québec., , Environmental health perspectives, 2002, 10.1289/ehp.02110607

Modulation of chromatin superstructure induced by poly(ADP-ribose) synthesis and degradation., , The Journal of biological chemistry, 1986

ADP-ribosylation of rye histones., , Canadian journal of biochemistry, 1980, 10.1139/o80-097

Stimulation of adenohypophyseal adenylate cyclase activity by synthetic luteinizing hormone-releasing hormone (LHRH) and purified growth hormone (GH-RH), , Hypothalamic hypophysiotropic hormones; physiological and clinical studies. Proceedings of the conference held at Acapulco, Gro., Mexico, June 29-July 1, 1972, 1973

Fibroblast growth factor-2 inhibits endothelial cell apoptosis by Bcl-2-dependent and independent mechanisms., , The American journal of pathology, 1997

Poly(ADP-ribose) glycohydrolase is present and active in mammalian cells as a 110-kDa protein., , Experimental cell research, 1999, 10.1006/excr.1998.4321

Association of poly(ADP-ribose) polymerase with nuclear subfractions catalyzed with sodium tetrathionate and hydrogene peroxide crosslinks., , Molecular and cellular biochemistry, 1996, 10.1007/BF00420918

Resistance of ADP-ribosylated histones and HMG proteins to proteases., , Biochemistry and cell biology = Biochimie et biologie cellulaire, 1992, 10.1139/o92-172

Ensconsin/Map7 promotes microtubule growth and centrosome separation in Drosophila neural stem cells., , The Journal of cell biology, 2014, 10.1083/jcb.201311094

Autoantibodies reacting with poly(ADP-ribose) and with a zinc-finger functional domain of poly(ADP-ribose) polymerase involved in the recognition of damaged DNA., , Clinical immunology and immunopathology, 1994, 10.1006/clin.1994.1187

A novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistance., , Cell death and differentiation, 2007, 10.1038/sj.cdd.4402116

Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death., , The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, 10.1523/JNEUROSCI.3461-04.2004

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions., , The Biochemical journal, 1999

Poly(ADP‐ribose) mediates bioenergetic defects and redox imbalance in neurons following oxygen and glucose deprivation, Shaida A. Andrabi, Ted M. Dawson, Valina L. Dawson, Peter H. King, Guy G. Poirier, Junaid Khan, Jean‐Philippe Gagné, Jun Hee Lee, M. Iqbal Hossain, The FASEB Journal, 2024, 10.1096/fj.202302559R

Differential proteomic screen to evidence proteins ubiquitinated upon mitotic exit in cell-free extract of Xenopus laevis embryos., , Journal of proteome research, 2008, 10.1021/pr800250x

Proteolytic degradation of poly(ADP-ribose) polymerase by contaminating proteases in commercial preparations of DNAse I, , ADP-ribosylation Reactions, 1992

Bcl-2 overexpression blocks activation of the death protease CPP32/Yama/apopain., , Biochemical and biophysical research communications, 1996, 10.1006/bbrc.1996.0597

ADP-ribosylation of pancreatic histone H1 and of other histones., , Canadian journal of biochemistry, 1980, 10.1139/o80-069

Proteasomes play an essential role in thymocyte apoptosis., , The EMBO journal, 1996

Distribution of muscarinic receptors in the digestive tract organs., , Pharmacology, 1981, 10.1159/000137489

Identification and analysis of caspase substrates: proteolytic cleavage of poly(ADP-ribose)polymerase and DNA fragmentation factor 45., , Methods in cell biology, 2001, 10.1016/s0091-679x(01)66013-8

Modulation of chromatin structure by poly(ADP-ribosyl)ation., , Biochemistry and cell biology = Biochimie et biologie cellulaire, 1988, 10.1139/o88-072

Retinoid induced apoptosis in leukemia cells through a retinoic acid nuclear receptor-independent pathway., , Blood, 1997

Muscarinic cholinergic receptors in pancreatic acinar carcinoma of rat., , International journal of cancer, 1985, 10.1002/ijc.2910350412

Poly ADP-ribosylation and DNA strand breakage in SV40 minichromosomes., , Carcinogenesis, 1985, 10.1093/carcin/6.2.283

Possible role of ADP-ribosylation of adenovirus core proteins in virus infection., , Virus research, 1986, 10.1016/0168-1702(86)90078-x

PARP inhibition: PARP1 and beyond., , Nature reviews. Cancer, 2010, 10.1038/nrc2812

The US-1 element from the gene encoding rat poly(ADP-ribose) polymerase binds the transcription factor Sp1., , European journal of biochemistry, 1993, 10.1111/j.1432-1033.1993.tb18008.x

PARPs database: a LIMS systems for protein-protein interaction data mining or laboratory information management system., , BMC bioinformatics, 2007, 10.1186/1471-2105-8-483

Dual function for poly(ADP-ribose) synthesis in response to DNA strand breakage., , Biochemistry, 1994, 10.1021/bi00189a012

Modulation of rat pancreatic amylase secretion and muscarinic receptor populations by chronic bethanechol treatment., , European journal of pharmacology, 1983, 10.1016/0014-2999(83)90637-4

prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2., , The Biochemical journal, 1996, 10.1042/bj3160025

The expanding role of poly(ADP-ribose) metabolism: current challenges and new perspectives., , Current opinion in cell biology, 2006, 10.1016/j.ceb.2006.02.013

Quality assessment of tandem mass spectra using support vector machine (SVM)., , BMC bioinformatics, 2009, 10.1186/1471-2105-10-S1-S49

Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks., , Trends in biochemical sciences, 1995, 10.1016/s0968-0004(00)89089-1

Determination of genotoxicity of the metabolites of the pesticides Guthion, Sencor, Lorox, Reglone, Daconil and Admire by 32P-postlabeling., , Molecular and cellular biochemistry, 1997, 10.1023/a:1006861621031

Hyperthermia and poly(ADP-ribose) metabolism, , ADP-ribose transfer reactions: mechanisms and biological significance, 1989

Automodification and NADase activity of poly(ADP-ribose) polymerase, , ADP-ribosylation Reactions, 1992

DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair., , Nucleic acids research, 2015, 10.1093/nar/gku1307

Different non-synonymous polymorphisms modulate the interaction of the WRN protein to its protein partners and its enzymatic activities., , Oncotarget, 2016, 10.18632/oncotarget.13341

Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B., , Proceedings of the National Academy of Sciences of the United States of America, 1996, 10.1073/pnas.93.5.1972

Cell cycle regulation of poly(ADP-ribose) synthetase in FR3T3 cells., , Biochimica et biophysica acta, 1988, 10.1016/0167-4889(88)90018-3

Analysis of the activation of poly(ADP-ribose) polymerase by various types of DNA., , Biochemistry and cell biology = Biochimie et biologie cellulaire, 1991, 10.1139/o91-086

Potential role of PARP inhibitors in cancer treatment and cell death, , DNA repair in cancer therapy, 2004

The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase, Anthony R. Fehr, Scott Lovell, Guy G. Poirier, Erik D. Holmstrom, David K. Johnson, Kevin P. Battaile, Louis Nonfoux, Philip Gao, Peter McDonald, Jean-Philippe Gagné, Anuradha Roy, Maithri M. Kashipathy, Yousef M.O. Alhammad, 2020, 10.1101/2020.05.11.089375

Expression of poly(ADP-ribose) polymerase in differentiating HL-60 cells, , ADP-ribosylation Reactions, 1992

Proteome profiling of human epithelial ovarian cancer cell line TOV-112D., , Molecular and cellular biochemistry, 2005, 10.1007/s11010-005-7556-1

Poly(ADP-ribose) glycohydrolase is a component of the FMRP-associated messenger ribonucleoparticles., , The Biochemical journal, 2005, 10.1042/BJ20050792

Parallel maturation of the pancreatic secretory response to cholinergic stimulation and the muscarinic receptor population., , British journal of pharmacology, 1981, 10.1111/j.1476-5381.1981.tb10428.x

Characterization of sPARP-1. An alternative product of PARP-1 gene with poly(ADP-ribose) polymerase activity independent of DNA strand breaks., , The Journal of biological chemistry, 2000, 10.1074/jbc.275.20.15504

Platelets release mitochondrial antigens in systemic lupus erythematosus., , Science translational medicine, 2021, 10.1126/scitranslmed.aav5928

Polypeptide receptor mechanisms in anterior pituitary gland, , Anatomical neuroendocrinology: based on the International Conference on Neurobiology of CNS-Hormone Interactions, Chapel Hill, N. C., May 14-16, 1974, 1975

Urinary Elimination of Bile Acid Glucuronides under Severe Cholestatic Situations: Contribution of Hepatic and Renal Glucuronidation Reactions., , Canadian journal of gastroenterology & hepatology, 2018, 10.1155/2018/8096314

Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor (TNF)-alpha: CrmA and Bcl-2 target distinct components in the apoptotic pathway., , The Journal of experimental medicine, 1997, 10.1084/jem.185.3.481

Different cleavage pattern for poly(ADP-ribose) polymerase during necrosis and apoptosis in HL-60 cells., , Biochemical and biophysical research communications, 1996, 10.1006/bbrc.1996.1889

Proteolytic cleavage of poly(ADP-ribose) polymerase in human leukemia cells treated with etoposide and other cytotoxic agents, , ADP-ribosylation Reactions, 1992

Poly(ADP-ribosyl)ation of chromatin in an in-vitro poly(ADP-ribose)-turnover system., , Biochimica et biophysica acta, 1992, 10.1016/0167-4889(92)90199-l

Characterization of the execution phase of apoptosis in vitro using extracts from condemned-phase cells., , Journal of cell science. Supplement, 1995, 10.1242/jcs.1995.supplement_19.6

NMDA but not non-NMDA excitotoxicity is mediated by Poly(ADP-ribose) polymerase., , The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000

Human Proteinpedia enables sharing of human protein data., , Nature biotechnology, 2008, 10.1038/nbt0208-164

Biochemical properties and function of poly(ADP-ribose) glycohydrolase., , Biochimie, 1995, 10.1016/0300-9084(96)88156-9

Properties of poly(ADP-ribose) synthetase from rat pancreas and poly(ADP-ribosylation) of basic nuclear proteins., , Canadian journal of biochemistry, 1978, 10.1139/o78-119

The effect of niacin deficiency on diethylnitrosamine-induced hepatic poly(ADP-ribose) levels and altered hepatic foci in the Fischer-344 rat., , Nutrition and cancer, 1995, 10.1080/01635589509514399

Failure of iniparib to inhibit poly(ADP-Ribose) polymerase in vitro., , Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, 10.1158/1078-0432.CCR-11-2890

Erasable blot of poly(ADP-ribose) polymerase., , Analytical biochemistry, 1994, 10.1006/abio.1994.1212

Reconstitution of an in vitro poly(ADP-ribose) turnover system., , Biochimica et biophysica acta, 1990, 10.1016/0167-4781(90)90083-e

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE., , Nature, 1994, 10.1038/371346a0

Poly(ADP-ribose) polymerase can bind melphalan damaged DNA., , Cancer research, 1993

Poly(ADP-ribose) (PAR) binding to apoptosis-inducing factor is critical for PAR polymerase-1-dependent cell death (parthanatos)., , Science signaling, 2011, 10.1126/scisignal.2000902

Activation of the p38 and JNK/SAPK mitogen-activated protein kinase pathways during apoptosis is mediated by a novel retinoid., , Experimental cell research, 1999, 10.1006/excr.1998.4350

Structural analysis of the putative regulatory region of the rat gene encoding poly(ADP-ribose) polymerase., , FEBS letters, 1992, 10.1016/0014-5793(92)80457-r

Erratum: Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination., , Genes & development, 2019, 10.1101/gad.324053.119

Poly(ADP) Ribose Polymerase at the Interface of DNA Damage Signaling and DNA Repair, , Advances in DNA Repair in Cancer Therapy, 2012

Mass spectrometry-based functional proteomics of poly(ADP-ribose) polymerase-1., , Expert review of proteomics, 2011, 10.1586/epr.11.63

PARP activation regulates the RNA-binding protein NONO in the DNA damage response to DNA double-strand breaks., , Nucleic acids research, 2012, 10.1093/nar/gks798

CrmA/SPI-2 inhibition of an endogenous ICE-related protease responsible for lamin A cleavage and apoptotic nuclear fragmentation., , The Journal of biological chemistry, 1996, 10.1074/jbc.271.51.32487

Immunolocalization of CENP-A suggests a distinct nucleosome structure at the inner kinetochore plate of active centromeres., , Current biology : CB, 1997, 10.1016/s0960-9822(06)00382-4

A framework for mass spectral quality assessment without prior information, , 7th IEEE International Conference on Bioinformatics and Bioengineering. Boston, MA (14-17 October 2007), 2007

Reprogramming cellular events by poly(ADP-ribose)-binding proteins., , Molecular aspects of medicine, 2013, 10.1016/j.mam.2012.12.005

Ataxia telangiectasia mutated (ATM) signaling network is modulated by a novel poly(ADP-ribose)-dependent pathway in the early response to DNA-damaging agents., , The Journal of biological chemistry, 2007, 10.1074/jbc.M608406200

Mapping PARP-1 auto-ADP-ribosylation sites by liquid chromatography-tandem mass spectrometry., , Journal of proteome research, 2013, 10.1021/pr301219h

Structural biology. PARP-1 activation--bringing the pieces together., , Science (New York, N.Y.), 2012, 10.1126/science.1221870

PARP1 parylation promotes silent locus transmission in the nucleolus: the suspicion confirmed., , Molecular cell, 2012, 10.1016/j.molcel.2012.03.012

Inferring gene regulatory networks with time delays using a genetic algorithm., , Systems biology, 2005, 10.1049/ip-syb:20050006

Poly(ADP-ribose) catabolism in mammalian cells., , Molecular and cellular biochemistry, 1994, 10.1007/BF00928442

Effect of potato suberin on Streptomyces scabies proteome., , Molecular plant pathology, 2008, 10.1111/j.1364-3703.2008.00493.x

The prefoldin complex stabilizes the von Hippel-Lindau protein against aggregation and degradation., , PLoS genetics, 2020, 10.1371/journal.pgen.1009183

Immunoelectron microscopical distribution of poly(ADP-ribose)polymerase in the mammalian cell nucleus., , Experimental cell research, 1988, 10.1016/0014-4827(88)90289-3

An approach to assessing peptide mass spectral quality without prior information, , International Journal of Functional Informatics and Personalised Medicine IJFIPM, 2008

Sequential ADP-ribosylation pattern of nucleosomal histones. ADP-ribosylation of nucleosomal histones., , European journal of biochemistry, 1985, 10.1111/j.1432-1033.1985.tb08650.x

Methods for biochemical study of poly(ADP-ribose) metabolism in vitro and in vivo., , Analytical biochemistry, 1995, 10.1006/abio.1995.1245

Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry., , Proteome science, 2010, 10.1186/1477-5956-8-22

DNA Damage Signalling and Repair Inhibitors: The Long-Sought-After Achilles' Heel of Cancer., , Biomolecules, 2015, 10.3390/biom5043204

Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment., , Biochemical and biophysical research communications, 1996, 10.1006/bbrc.1996.1565

Quantitative site-specific ADP-ribosylation profiling of DNA-dependent PARPs., , DNA repair, 2015, 10.1016/j.dnarep.2015.02.004

Enzymatic properties of Poly(ADP-ribose) polymerase and poly(ADP-ribose) glycohydrolase on chromatin, , ADP-ribosylation Reactions, 1992

Analysis of ADP-ribose polymer sizes in intact cells., , Molecular and cellular biochemistry, 2001, 10.1023/a:1011910329010

Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin to Promote Mitotic Spindle Assembly., , Current biology : CB, 2021, 10.1016/j.cub.2020.11.009

tej defines a role for poly(ADP-ribosyl)ation in establishing period length of the arabidopsis circadian oscillator., , Developmental cell, 2002, 10.1016/s1534-5807(02)00200-9

Changes in acetylcholinesterase and cholinesterase activities in rat pancreas during postnatal development. Lack of relation with muscarinic receptor maturation., , Pharmacology, 1984, 10.1159/000137990

Caspase-3-mediated processing of poly(ADP-ribose) glycohydrolase during apoptosis., , The Journal of biological chemistry, 2001, 10.1074/jbc.M007269200

Poly(ADP-ribose) (PAR) polymer is a death signal., , Proceedings of the National Academy of Sciences of the United States of America, 2006, 10.1073/pnas.0606526103

SULT4A1 Protects Against Oxidative-Stress Induced Mitochondrial Dysfunction in Neuronal Cells., , Drug metabolism and disposition: the biological fate of chemicals, 2019, 10.1124/dmd.119.088047

DNA base excision repair stimulates poly(ADP-ribose synthesis, , ADP-ribosylation Reactions, 1992

CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage., , Nucleic acids research, 2012, 10.1093/nar/gks222

Adenosine diphosphate ribosylation of proteins in rat pancreas [proceedings]., , Biochemical Society transactions, 1980, 10.1042/bst0080192

PARP1-dependent kinetics of recruitment of MRE11 and NBS1 proteins to multiple DNA damage sites., , The Journal of biological chemistry, 2008, 10.1074/jbc.M706734200

Hypophysiotropic hormones, cyclic AMP and adenohypophyseal protein synthesis and release, , Hormones and brain function. [Proceedings of the second congress of the International Society of Psychoneuroendocrinology held in Budapest (Hungary) from July 1 to 3, 1971] Edited by K. Lissâak, 1973

Structural and functional analysis of poly(ADP ribose) polymerase: an immunological study., , Biochimica et biophysica acta, 1988, 10.1016/0167-4781(88)90007-3

One-step protein purification using micropreparative electrophoresis fully compatible with protein microsequencing., , Analytical biochemistry, 1994, 10.1006/abio.1994.1437

Poly(ADP-ribose) polymerase-1 is a positive regulator of the p53-mediated G1 arrest response following ionizing radiation., , The Journal of biological chemistry, 2003, 10.1074/jbc.M211641200

Muscarinic receptor of rat pancreatic acini: [3H]QNB binding and amylase., , European journal of pharmacology, 1981, 10.1016/0014-2999(81)90508-2

Extrusion of earthworm coelomocytes: comparison of the cell populations recovered from the species Lumbricus terrestris, Eisenia fetida and Octolasion tyrtaeum., , Laboratory animals, 1997, 10.1258/002367797780596068

Focus on computational proteomics., , Proteomics, 2011, 10.1002/pmic.201190099

Production and characterization of monoclonal antibodies specific for the functional domains of poly(ADP-ribose) polymerase., , Biochemistry and cell biology = Biochimie et biologie cellulaire, 1986, 10.1139/o86-051

Regulation of poly(ADP-ribose) metabolism by poly(ADP-ribose) glycohydrolase: where and when?, , Cellular and molecular life sciences : CMLS, 2005, 10.1007/s00018-004-4505-1

Rapid detection of poly(ADP-ribose) polymerase by enzyme-linked immunosorbent assay during its purification and improvement of its purification., , Molecular and cellular biochemistry, 1998, 10.1023/a:1006861015142

Effects of transient global ischemia and kainate on poly(ADP-ribose) polymerase (PARP) gene expression and proteolytic cleavage in gerbil and rat brains., , Brain research. Molecular brain research, 2000, 10.1016/s0169-328x(00)00122-4

Localization of the zinc-binding sites in the DNA-binding domain of the bovine poly(ADP-ribose) polymerase, , ADP-ribose transfer reactions: mechanisms and biological significance, 1989

Insulin-dependent phosphorylation of DPP IV in liver. Evidence for a role of compartmentalized c-Src., , The FEBS journal, 2006, 10.1111/j.1742-4658.2006.05125.x

A microassay for the detection of low levels of cytochrome P450 O-deethylation activities with alkoxyresorufin substrates., , Molecular and cellular biochemistry, 1997, 10.1023/a:1006835712436

Bcl-2 acts upstream of the PARP protease and prevents its activation., , Cell death and differentiation, 1997, 10.1038/sj.cdd.4400200

Enhanced killing of cancer cells by poly(ADP-ribose) polymerase inhibitors and topoisomerase I inhibitors reflects poisoning of both enzymes., , The Journal of biological chemistry, 2012, 10.1074/jbc.M111.296475

Base excision repair is efficient in cells lacking poly(ADP-ribose) polymerase 1., , Nucleic acids research, 2000, 10.1093/nar/28.20.3887

Alteration in methyl-methanesulfonate-induced poly(ADP-ribosyl)ation by 2-butoxyethanol in Syrian hamster embryo cells., , Carcinogenesis, 1997, 10.1093/carcin/18.12.2333

Equilibrium model in an in vitro poly(ADP-ribose) turnover system., , Biochimica et biophysica acta, 1995, 10.1016/0167-4781(95)00143-5

Cigarette smoking during pregnancy: comparison of biomarkers for inclusion in epidemiological studies, , Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2001

The RNF138 E3 ligase displaces Ku to promote DNA end resection and regulate DNA repair pathway choice., , Nature cell biology, 2015, 10.1038/ncb3259

The RAD51 paralogs ensure cellular protection against mitotic defects and aneuploidy., , Journal of cell science, 2013, 10.1242/jcs.114595

Poly(ADP-ribose) degradation by post-nuclear extracts from human cells., , Biochimie, 2002, 10.1016/s0300-9084(02)00017-2

Niacin deficiency decreases bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats., , The Journal of nutrition, 2002, 10.1093/jn/132.1.108

Spatial and functional relationship between poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase in the brain., , Neuroscience, 2007, 10.1016/j.neuroscience.2007.04.062

Enzymatic mechanisms for joining DNA strand interruptions in human cells, , DNA repair mechanisms: proceedings of the Alfred Benzon Symposium 35, held at the premises of the Royal Danish Academy of Sciences and Letters, Copenhagen, August 9-13, 1992, 1993

Adenosine diphosphate ribosylation of chicken-erythrocyte histones H1, H5 and high-mobility-group proteins by purified calf-thymus poly(adenosinediphosphate-ribose) polymerase., , European journal of biochemistry, 1982, 10.1111/j.1432-1033.1982.tb06891.x

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme., , Molecular cell, 2007, 10.1016/j.molcel.2007.06.027

Sources of nitrate exposure in residents of rural areas in Quebec, Canada., , Journal of exposure analysis and environmental epidemiology, 2000, 10.1038/sj.jea.7500079

Cytotoxic T-cell-derived granzyme B activates the apoptotic protease ICE-LAP3., , Current biology : CB, 1996, 10.1016/s0960-9822(02)00614-0

Characterization of anti-peptide antibodies directed towards the automodification domain and apoptotic fragment of poly (ADP-ribose) polymerase., , Biochimica et biophysica acta, 1997, 10.1016/s0304-4165(96)00077-3

The von Hippel-Lindau tumour suppressor gene: uncovering the expression of the pVHL172 isoform., , British journal of cancer, 2015, 10.1038/bjc.2015.189

Molecular and biochemical features of poly (ADP-ribose) metabolism., , Molecular and cellular biochemistry, 1993, 10.1007/BF01076101

Apparent cleavage of poly(ADP-ribose) polymerase in non-apoptotic mouse LTA cells: an artifact of cross-reactive secondary antibody., , Molecular and cellular biochemistry, 1998, 10.1023/a:1006808001462

Influence of duration of focal cerebral ischemia and neuronal nitric oxide synthase on translocation of apoptosis-inducing factor to the nucleus., , Neuroscience, 2007, 10.1016/j.neuroscience.2006.08.065

Cloning and expression of a rat brain interleukin-1beta-converting enzyme (ICE)-related protease (IRP) and its possible role in apoptosis of cultured cerebellar granule neurons., , The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997

RT-PSM, a real-time program for peptide-spectrum matching with statistical significance., , Rapid communications in mass spectrometry : RCM, 2006, 10.1002/rcm.2435

Niacin deficiency increases the sensitivity of rats to the short and long term effects of ethylnitrosourea treatment., , Molecular and cellular biochemistry, 1999

Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair., , Proceedings of the National Academy of Sciences of the United States of America, 2021, 10.1073/pnas.2019408118

Diethylnitrosamine administration in vivo increases hepatic poly(ADP-ribose) levels in rats: results of a modified technique for poly(ADP-ribose) measurement., , Carcinogenesis, 1993, 10.1093/carcin/14.12.2513

DNA replication and poly(ADP-ribosyl)ation of chromatin., , Cytobios, 1989

Activation of cysteine proteases in cowpea plants during the hypersensitive response--a form of programmed cell death., , Experimental cell research, 1998, 10.1006/excr.1998.4256

A HUPO test sample study reveals common problems in mass spectrometry-based proteomics., , Nature methods, 2009, 10.1038/nmeth.1333

ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B., , The Journal of biological chemistry, 1996, 10.1074/jbc.271.28.16720

Quantitative proteomic analysis of amphotericin B resistance in Leishmania infantum., , International journal for parasitology. Drugs and drug resistance., 2014, 10.1016/j.ijpddr.2014.05.002

Zinc is a potent inhibitor of the apoptotic protease, caspase-3. A novel target for zinc in the inhibition of apoptosis., , The Journal of biological chemistry, 1997, 10.1074/jbc.272.30.18530

Poly(adenosine diphosphoribose) polymerase activity and adenosine diphosphate ribosylation of proteins during pancreatic degeneration and regeneration., , Cancer research, 1981

Disruptor of telomeric silencing-1 is a chromatin-specific histone H3 methyltransferase., , The Journal of biological chemistry, 2002, 10.1074/jbc.C200366200

PARP-1-induced cell death through inhibition of the MEK/ERK pathway in MNNG-treated HeLa cells., , Apoptosis : an international journal on programmed cell death, 2007, 10.1007/s10495-007-0127-z

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase., , The EMBO journal, 1997, 10.1093/emboj/16.19.6018

Les réactions de poly(ADP-ribosyl)ation, , Regards sur la biochimie, 1988

A Context-Dependent Role for the RNF146 Ubiquitin Ligase in Wingless/Wnt Signaling in ., , Genetics, 2019, 10.1534/genetics.118.301393

Mode of action of poly(ADP-ribose) glycohydrolase., , Biochimica et biophysica acta, 1994, 10.1016/0167-4781(94)90058-2

Poly(ADP-ribosyl)ation-dependent Transient Chromatin Decondensation and Histone Displacement following Laser Microirradiation., , The Journal of biological chemistry, 2016, 10.1074/jbc.M115.694992

Chromosomal protein poly(ADP-ribosyl)ation in pancreatic nucleosomes., , Canadian journal of biochemistry, 1982, 10.1139/o82-036

Importance of poly(ADP-ribose) glycohydrolase in the control of poly(ADP-ribose) metabolism., , Experimental cell research, 2001, 10.1006/excr.2001.5263

PARP-1 activation leads to cytosolic accumulation of TDP-43 in neurons., , Neurochemistry international, 2021, 10.1016/j.neuint.2021.105077

Niacin deficiency in rats increases the severity of ethylnitrosourea-induced anemia and leukopenia., , The Journal of nutrition, 2000, 10.1093/jn/130.5.1102

Découvrez nos professeurs et professeures!

Guy Poirier

Projets de recherche en cours

Financements des 2 dernières années

Publications

Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Vice-décanat à la recherche et à l'innovation