Découvrez nos professeurs et professeures!

Guy Boivin

Médecin clinicien enseignant titulaire

guy.boivin@fmed.ulaval.ca

Site personnel

Département de pédiatrie

Centre de recherche en infectiologie

Centre de recherche du CHU de Québec - Université Laval

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Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Immunologie-infectiologie

Domaines et intérêts de recherche du (de la) professeur(e) :

Maladies infectieuses et immunitaires

Virus
Infections virales
Antiviraux
Développement de vaccins
Anticorps
Santé internationale et pathologies émergentes
Immunothérapie

Projets de recherche

Identification of innate immune pathways as targets for immunomodulatory therapy in herpes simplex virus encephalitis - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2023-10-01 au 2028-09-30
Laboratoire international associé (LIA) sur la pathogenèse, le traitement et la prévention des infections virales respiratoires (LIA RespiVIR) - Université Laval - Fonds internes - Laboratoire international associé (LIA), chercheur principal - 2021-07-27 au 2026-07-26
Mise au point d'un modèle animal pour l'infection avec le virus parainfluenza-3 - CHU de Québec – Université Laval – CHUL - Développement de la recherche (FC), chercheur principal - 2024-01-10 au 2026-01-10
Plateforme de laboratoire de niveau de confinement 3 pour la recherche sur les virus émergents - CHU de Québec – Université Laval – CHUL, Ministère de l'Économie et de l'Innovation - Appel de projets en appui aux plateformes technologiques stratégiques, chercheur principal - 2023-01-31 au 2025-03-31
Fonds institutionnel d'exploitation des infrastructures pour l'Université Laval - Fondation Canadienne pour l'innovation (La) - Fonds d'exploitation des infrastructures (FEI), co-chercheur - 2002-04-01 au 2025-03-31
Évaluation des interactions entre des virus respiratoires - CHU de Québec – Université Laval – CHUL - Développement de la recherche (FC), chercheur principal - 2022-02-01 au 2025-01-31
Changement de paradigme dans la conduite d'essais cliniques - Ministère de l'Économie et de l'Innovation, Université de Montréal, co-chercheur - 2021-04-01 au 2024-03-31
Antiviral Resistance and Benefits of Combination Therapy for Influenza Viruses - Instituts de recherche en santé du Canada - Subvention Projet, chercheur principal - 2023-03-01 au 2024-02-29
Relationship between COVID-19 and Parkinson’s disease in a mouse model - Parkinson Canada - Pilot Project Grant, co-chercheur - 2022-10-01 au 2023-09-30
A research program on the pathogenesis, treatment and prevention of respiratory and herpes viruses - Instituts de recherche en santé du Canada - Subventions Fondation, chercheur principal - 2016-07-01 au 2023-06-30
Sentinel Surveillance for Severe Outcomes of Laboratory-Confirmed Influenza in Adults for the Annual Influenza Season and for Confirmed and Suspected Cases Of Covid-19/Sars-Cov-2 Acute Respiratory Disease, Covid-19 Vaccine Effectiveness and - Instituts de recherche en santé du Canada - Réseau canadien de recherche sur l’immunisation, Dalhousie University, co-chercheur - 2022-04-01 au 2023-03-31
SO05 QC07, Sentinel surveillance for confirmed and suspected cases of covid-19/covsars-2 acute respiratory disease, covid-19 vaccine effectiveness and adverse events following sars-cv-2 vaccines: A study of the Serious Outcomes Surveillance - Instituts de recherche en santé du Canada - Réseau canadien de recherche sur l’immunisation, co-chercheur - 2021-04-01 au 2023-03-31
COVIGRO : Impact de la COVID-19 et du vaccin contre SARS-CoV-2 sur le développement placentaire et foetal - Instituts de recherche en santé du Canada - Subvention de fonctionnement:Nouveaux besoins prioritaires en recherche sur la COVID-19, co-chercheur - 2021-12-01 au 2022-11-30
CHOIR study: Children and Older Teens Immune Response to SARS-CoV-2 in Montreal - Instituts de recherche en santé du Canada - Subvention de fonctionnement:Nouveaux besoins prioritaires en recherche sur la COVID-19, Université de Montréal, co-chercheur - 2021-12-01 au 2022-11-30
How to better manage infectious diseases in ER by triage with molecular mini-panels for the rapid detection of highly transmissible pathogens - Consortium québécois sur la découverte du médicament, co-chercheur - 2018-10-01 au 2022-09-30
Hospital-based surveillance of influenza and routine monitoring of seasonal influenza vaccine effectiveness (VE) - Services publics et Approvisionnement Canada, Dalhousie University, co-chercheur - 2020-11-01 au 2022-09-30
Manufacturing of antigens and adjuvants for development of vaccines (MAAV) - Fondation Canadienne pour l'innovation (La), Ministère de la Santé et des Services sociaux, Fondation du CHU de Québec - Fonds d'innovation (FI), co-chercheur - 2020-11-01 au 2022-03-31
Innovative therapeutic approaches for the 2019-novel coronavirus - Instituts de recherche en santé du Canada, Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC) - Subvention de fonctionnement : Possibilité de financement canadienne pour une intervention de recherche rapide contre la maladie à coronavirus 2019 (COVID-19), chercheur principal - 2021-03-01 au 2022-02-28
Children, school personnel, and COVID-19 : seroprevalence study in Montréal - Agence de la santé publique du Canada - Groupe de travail sur l'immunité face à la COVID 19, chercheur principal - 2020-12-01 au 2021-12-31

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Publications

Influenza virus activates human immunodeficiency virus type-1 gene expression in human CD4-expressing T cells through an NF-kappaB-dependent pathway., Tremblay MJ, Boivin G, Barbeau B, Bergeron M, Sun J, Clinical immunology (Orlando, Fla.), 2005, 10.1016/j.clim.2004.10.002
Three-dimensional modeling of cytomegalovirus DNA polymerase and preliminary analysis of drug resistance., Lin SX, Boivin G, Gilbert C, Azzi A, Shi R, Proteins, 2006, 10.1002/prot.21005
Influenza vaccine effectiveness to prevent influenza-related hospitalizations and serious outcomes in Canadian adults over the 2011/12 through 2013/14 influenza seasons: A pooled analysis from the Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS Network), McNeil, S.A., Ye, L., Webster, D., Valiquette, L., Trottier, S., Taylor, G., Stiver, G., Smyth, D., Smith, S., Shinde, V., Semret, M., Schuind, A., Richardson, D., Powis, J., Poirier, A., McGeer, A., McElhaney, J.E., McCarthy, A., MacKinnon-Cameron, D., Loeb, M., LeBlanc, J., Langley, J.M., Lagacé-Wiens, P., Katz, K., Johnstone, J., Ibarguchi, B., Halperin, S.A., Haguinet, F., Green, K., ElSherif, M., Dos Santos, G., Chit, A., Bowie, W., Boivin, G., Ambrose, A., Hatchette, T.F., Andrew, M.K., Nichols, M.K., Vaccine, 2018, 10.1016/j.vaccine.2018.02.093
Impact of the H275Y and I223V mutations in the neuraminidase of the 2009 pandemic influenza virus in vitro and evaluating experimental reproducibility, Beauchemin, C.A.A., Boivin, G., Abed, Y., Holder, B.P., Pinilla, L.T., Paradis, E.G., PLoS ONE, 2015, 10.1371/journal.pone.0126115
The REinfection in COVID‐19 Estimation of Risk (RECOVER) study: Reinfection and serology dynamics in a cohort of Canadian healthcare workers, Caroline Quach‐Thanh, Gaston De Serres, Jacques Corbeil, Vladimir Gilca, Sabryna Nantel, Benoîte Bourdin, Kelsey Adams, Fazia Tadount, Julie Carbonneau, Marie‐Ève Hamelin, Matthew P. Cheng, Patrice Savard, Hélène Decaluwe, Deirdre McCormack, Yves Longtin, Guy Boivin, Étienne Racine, Influenza and Other Respiratory Viruses, 2022, 10.1111/irv.12997
An outbreak of severe respiratory tract infection due to human metapneumovirus in a long-term care facility., Couture C, Boulianne N, Ouakki M, Sauvageau C, Maranda-Aubut R, Tremblay G, Argouin M, Côté S, Hamelin ME, De Serres G, Boivin G, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, 10.1086/513204
Herpesvirus Resistance, W.L. Drew, G. Boivin, Antimicrobial Drug Resistance, 2009, 10.1007/978-1-60327-595-8_24
Recent advances in management of genital herpes., Boivin G, Tétrault I, Canadian family physician Medecin de famille canadien, 2000
Prophylactic and therapeutic benefits of a monoclonal antibody against the fusion protein of human metapneumovirus in a mouse model., Boivin G, Ulbrandt N, Suzich J, Kiener P, Prince GA, Gagnon C, Hamelin ME, Antiviral research, 2010, 10.1016/j.antiviral.2010.07.001
Fluorescent polymeric transducer for the rapid, simple, and specific detection of nucleic acids at the zeptomole level., Leclerc M, Boudreau D, Bergeron MG, Boivin G, Boissinot M, Corbeil G, Brunette M, Lévesque I, Ho HA, Dubus S, Doré K, Journal of the American Chemical Society, 2004, 10.1021/ja038900d
Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility., Boivin G, Götte M, Drouot E, Eckenroth BE, Goyette N, Piret J, Journal of virology, 2015, 10.1128/jvi.03360-14
Reply , Boivin G, The Journal of infectious diseases, 1998, 10.1086/314472
DNA vaccination protects mice against Zika virus-induced damage to the testes, Kobinger, G.P., Weiner, D.B., Safronetz, D., Embury-Hyatt, C., Kobasa, D., Booth, S.A., Boivin, G., Lindsay, R., Bello, A., Yao, X.-J., Kim, J.J., Sardesai, N.Y., Maslow, J.N., Park, Y.K., Smid, V., McTavish, G., Scott, J., Scharikow, L., Soule, G., De Graff, C., Frost, K.L., Tran, K.N., Kucas, S., Piret, J., De La Vega, M.-A., Racine, T., Ranadheera, C., Stein, D.R., Audet, J., Hagan, M., Majer, A., Warner, B.M., Muthumani, K., Griffin, B.D., Nature Communications, 2017, 10.1038/ncomms15743
Cytomegalovirus ventriculoencephalitis in a peripheral blood stem cell transplant recipient., Tang YW, Kassim A, Becher MW, McConnell T, Dummer JS, Boivin G, Miller GG, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, 10.1086/499366
Human metapneumovirus., Boivin G, Hamelin ME, Deffrasnes C, Seminars in respiratory and critical care medicine, 2007, 10.1055/s-2007-976493
Characterization of 2 influenza A(H3N2) clinical isolates with reduced susceptibility to neuraminidase inhibitors due to mutations in the hemagglutinin gene., Boivin G, Tisdale M, Owens IJ, Gower D, Morley PJ, Fenton RJ, Bourgault AM, Abed Y, The Journal of infectious diseases, 2002, 10.1086/344237
Validation of the Seegene RV15 multiplex PCR for the detection of influenza A subtypes and influenza B lineages during national influenza surveillance in hospitalized adults, McNeil, S.A., Ye, L., Webster, D., Valiquette, L., Trottier, S., Smyth, D., Shinde, V., Semret, M., Richardson, D., Powis, J., Poirier, A., McGeer, A., McElhaney, J.E., McCarthy, A., MacKinnon-Cameron, D., Lund, A., Loeb, M., Lagacé-Wiens, P., Langley, J.M., Katz, K., Johnstone, J., Ibarguchi, B., Hatchette, T.F., Halperin, S.A., Green, K., Dos Santos, G., Chit, A., Bowie, W., Boivin, G., Andrew, M., Ambrose, A., Warhuus, M., Mulpuru, S., ElSherif, M., LeBlanc, J.J., Journal of Medical Microbiology, 2020, 10.1099/jmm.0.001032
Immunomodulatory strategies in herpes simplex virus encephalitis, Boivin, G., Piret, J., Clinical Microbiology Reviews, 2020, 10.1128/CMR.00105-19
Molecular evolution of influenza A/H3N2 viruses in the province of Québec (Canada) during the 1997-2000 period., Boivin G, Goyette N, Coulthart MB, Li Y, Hardy I, Virus research, 2001, 10.1016/s0168-1702(01)00269-6
Analysis of cytomegalovirus DNA polymerase (UL54) mutations in solid organ transplant patients receiving valganciclovir or ganciclovir prophylaxis., Covington E, Gilbert C, Goyette N, Boivin G, Journal of medical virology, 2005, 10.1002/jmv.20471
Discordant phenotypes and genotypes of cytomegalovirus (CMV) in patients with AIDS and relapsing CMV retinitis., Boivin G, Gilbert C, AIDS (London, England), 2003, 10.1097/00002030-200302140-00007
Human metapneumovirus viral load is an important risk factor for disease severity in young children, Boivin, G., De Serres, G., Hamelin, M.-T., Papenburg, J., Ouakki, M., Carbonneau, J., Roussy, J.-F., Journal of Clinical Virology, 2014, 10.1016/j.jcv.2014.03.001
RSV and HMPV Infections in 3D Tissue Cultures: Mechanisms Involved in Virus-Host and Virus-Virus Interactions, Essaidi-Laziosi, M., Tapparel, C., Kaiser, L., Constant, S., Huang, S., Boivin, G., Geiser, J., Viruses, 2021, 10.3390/v13010139
Long-term impairment of Streptococcus pneumoniae lung clearance is observed after initial infection with influenza A virus but not human metapneumovirus in mice, Boivin, G., Hamelin, M.E., Aerts, L., Ludewick, H.P., Journal of General Virology, 2011, 10.1099/vir.0.030825-0
Comparative evaluation of the cytomegalovirus DNA load in polymorphonuclear leukocytes and plasma of human immunodeficiency virus-infected subjects., Bergeron MG, Lalonde R, Murray G, Toma E, Handfield J, Boivin G, The Journal of infectious diseases, 1998, 10.1086/514190
Comparison of risk factors for human metapneumovirus and respiratory syncytial virus disease severity in young children., Boivin G, De Serres G, Frenette L, Caouette G, Corbeil J, Robitaille L, Raymond F, Ouakki M, Carbonneau J, Ouhoummane N, Hamelin MÈ, Papenburg J, The Journal of infectious diseases, 2012, 10.1093/infdis/jis333
Activity of the oral neuraminidase inhibitor A-322278 against the oseltamivir-resistant H274Y (A/H1N1) influenza virus mutant in mice., Boivin G, Nehmé B, Abed Y, Baz M, Antimicrobial agents and chemotherapy, 2008, 10.1128/aac.01276-08
Therapeutic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H275Y neuraminidase mutation., Boivin G, Pizzorno A, Abed Y, Antimicrobial agents and chemotherapy, 2012, 10.1128/aac.00753-12
Role of permissive neuraminidase mutations in influenza A/Brisbane/59/2007-like (H1N1) viruses, Boivin, G., Bouhy, X., Pizzorno, A., Abed, Y., PLoS Pathogens, 2011, 10.1371/journal.ppat.1002431
Antiviral agents in development for zika virus infections, Boivin, G., Baz, M., Pharmaceuticals, 2019, 10.3390/ph12030101
The need for validation of statistical methods for estimating respiratory virus-attributable hospitalization., Buckeridge DL, Boivin G, Skowronski D, De Serres G, Gilca R, American journal of epidemiology, 2009, 10.1093/aje/kwp195
Absence of cytomegalovirus-resistance mutations after valganciclovir prophylaxis, in a prospective multicenter study of solid-organ transplant recipients., Covington E, Freeman R, Alexander B, Blumberg E, Washburn K, Dominguez E, Humar A, Paya C, Pescovitz MD, Macey K, Roberts N, Gilbert C, Boivin G, Goyette N, The Journal of infectious diseases, 2004, 10.1086/382753
Amphipathic DNA polymers exhibit antiherpetic activity in vitro and in vivo., Vaillant A, Juteau JM, Ireland J, Boivin G, Kern ER, Cardin R, Goyette N, Bernstein DI, Antimicrobial agents and chemotherapy, 2008, 10.1128/aac.00279-08
Impact of mutations at residue I223 of the neuraminidase protein on the resistance profile, replication level, and virulence of the 2009 pandemic influenza virus, Boivin, G., Russell, R., Mallett, C., Beaulieu, É., Bouhy, X., Abed, Y., Pizzorno, A., Antimicrobial Agents and Chemotherapy, 2012, 10.1128/AAC.05994-11
Modulation of TLR9 response in a mouse model of herpes simplex virus encephalitis., Boivin G, Piret J, Menasria R, Boivin N, Antiviral research, 2012, 10.1016/j.antiviral.2012.09.022
Impact of deficiency in CCR2 and CX3CR1 receptors on monocytes trafficking in herpes simplex virus encephalitis., Rivest S, Boivin G, Gosselin D, Menasria R, Boivin N, The Journal of general virology, 2012, 10.1099/vir.0.041046-0
Effects of different drug combinations in immunodeficient mice infected with an influenza a/h3n2 virus, Baz, M., Boivin, G., Kobinger, G., Abed, Y., Venable, M.-C., Carbonneau, J., Uyar, O., Fausther-Bovendo, H., Mhamdi, Z., Microorganisms, 2020, 10.3390/microorganisms8121968
Quantitation of cytomegalovirus: methodologic aspects and clinical applications., Boivin G, Boeckh M, Clinical microbiology reviews, 1998, 10.1128/cmr.11.3.533
Detection and management of antiviral resistance for influenza viruses, Boivin, G., Influenza and other Respiratory Viruses, 2013, 10.1111/irv.12176
Human herpesvirus 8 DNA load in leukocytes of human immunodeficiency virus-infected subjects: correlation with the presence of Kaposi's sarcoma and response to anticytomegalovirus therapy., Bergeron MG, Handfield J, Murray G, Routy JP, Lalonde R, Toma E, Gaudreau A, Boivin G, Antimicrobial agents and chemotherapy, 1999, 10.1128/aac.43.2.377
Divergent evolution of hemagglutinin and neuraminidase genes in recent influenza A:H3N2 viruses isolated in Canada., Boivin G, Li Y, Hardy I, Abed Y, Journal of medical virology, 2002, 10.1002/jmv.10143
Amphipathic DNA polymers are candidate vaginal microbicides and block herpes simplex virus binding, entry and viral gene expression., Herold BC, Boivin G, Vaillant A, Juteau JM, Goyette N, Keller MJ, Shende V, Cheshenko N, Guzman EM, Antiviral therapy, 2007
Heterosubtypic protection conferred by the human monoclonal antibody PN-SIA28 against influenza A virus lethal infections in mice., Boivin G, Burioni R, Clementi M, Mancini N, Clementi N, Cappelletti F, Rhéaume C, Abed Y, Retamal M, Antimicrobial agents and chemotherapy, 2015, 10.1128/aac.00118-15
Resistance of Herpesviruses to Antiviral Agents, W. L. Drew, G. Boivin, Antimicrobial Resistance and Implications for the Twenty-First Century, 1911, 10.1007/978-0-387-72418-8_8
Development and validation of an enzyme-linked immunosorbent assay for human metapneumovirus serology based on a recombinant viral protein., Boivin G, Hamelin ME, Clinical and diagnostic laboratory immunology, 2005, 10.1128/cdli.12.2.249-253.2005
Cytomegalovirus (CMV) virus load kinetics to predict recurrent disease in solid-organ transplant patients with CMV disease., Caliendo AM, Boivin G, Kumar D, Humar A, The Journal of infectious diseases, 2002, 10.1086/342601
Seroprevalence of anti-SARS-CoV-2 antibodies among school and daycare children and personnel: Protocol for a cohort study in Montreal, Canada, Quach C, Savard-Lamothe A, Pierce L, Apostolatos A, Saucier A, Hamelin M, Fortin G, Papenburg J, Charland K, Zahreddine M, Bourque N, McKinnon B, Zinszer K, 2021, 10.1101/2021.04.14.21255499
Human metapneumovirus infection in adults with community-acquired pneumonia and exacerbation of chronic obstructive pulmonary disease., Boivin G, DeSerres G, Gilca R, Weiss K, Bourbeau J, Lampron N, Laforge J, Côté S, Hamelin ME, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, 10.1086/431981
Antiviral drug resistance in herpesviruses, Boivin, G., Drouot, E., Piret, J., Handbook of Antimicrobial Resistance, 2017, 10.1007/978-1-4939-0694-9_7
E119D Neuraminidase Mutation Conferring Pan-Resistance to Neuraminidase Inhibitors in an A(H1N1)pdm09 Isolate from a Stem-Cell Transplant Recipient, Kaiser, L., Boivin, G., Boquete-Suter, P., Zdobnov, E., Van Delden, C., Chalandon, Y., Simon, A., Schibler, M., Bouhy, X., Thomas, Y., Cordey, S., Petty, T.J., Abed, Y., L'Huillier, A.G., Journal of Infectious Diseases, 2015, 10.1093/infdis/jiv288
Influenza virus epidemiology: A permanent vaccine challenge,Épidémiologie des virus influenza: Le défi vaccinal permanent, Lina, B., Boivin, G., Virologie, 2019, 10.1684/vir.2019.0788
Treatment with a novel topical nanoemulsion (NB-001) speeds time to healing of recurrent cold sores., NB-001 Study Group, Baker JR, Stanberry LR, Boivin G, Sutcliffe J, Ciotti S, Ijzerman M, Flack MR, Jarratt M, Jones TM, Kircik L, Journal of drugs in dermatology : JDD, 2012
New Saffold cardioviruses in 3 children, Canada., Boivin G, Abed Y, Emerging infectious diseases, 2008, 10.3201/eid1405.071675
Hydroxyurea enhances the activity of acyclovir and cidofovir against herpes simplex virus type 1 resistant strains harboring mutations in the thymidine kinase and/or the DNA polymerase genes., Boivin G, Sergerie Y, Antiviral research, 2007, 10.1016/j.antiviral.2007.08.009
Assessing the diagnostic accuracy of PCR-based detection of Streptococcus pneumoniae from nasopharyngeal swabs collected for viral studies in Canadian adults hospitalised with community-acquired pneumonia: A Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research (CIRN) study, Stiver, G., Bowie, W., Johnstone, J., Loeb, M., McGeer, A., McCarthy, A., Semret, M., Valiquette, L., Boivin, G., Trottier, S., Webster, D., Andrew, M., LeBlanc, J.J., McNeil, S.A., Hatchette, T.F., Martin, I., Elsherif, M., Lang, A.L.S., Gillis, H.D., BMJ Open, 2017, 10.1136/bmjopen-2016-015008
Viral pathogens including human metapneumovirus are the primary cause of febrile respiratory illness in HIV-infected adults receiving antiretroviral therapy., Boivin G, Frost E, Carbonneau J, DelBalso L, Yang H, Klein MB, The Journal of infectious diseases, 2010, 10.1086/649587
Molecular and epidemiologic investigation of a rhinovirus outbreak in a neonatal intensive care unit, Papenburg, J., Lefebvre, M.-A., Boivin, G., Beltempo, M., Fontela, P.S., Caya, C., Quach, C., Lafond, M., Carbonneau, J., Isabel, S., El Idrissi, K.R., Infection Control and Hospital Epidemiology, 2019, 10.1017/ice.2018.311
Modified cyclodextrins as broad-spectrum antivirals, Tapparel, C., Stellacci, F., Boivin, G., Kirkegaard, K., Constant, S., Huang, S., Kaiser, L., Král, P., Vuković, L., Han, Y., Constant, D.A., Gasbarri, M., Piret, J., Gasilova, N., Ortiz, D., Janeček, M., Cagno, V., Jones, S.T., Science Advances, 2020, 10.1126/sciadv.aax9318
Reduced airborne transmission of oseltamivir-resistant pandemic A/H1N1 virus in ferrets., Boivin G, Mallett C, Dubé K, Beaulieu E, Bouhy X, Baz M, Hamelin ME, Antiviral therapy, 2011, 10.3851/imp1794
Influenza virus shedding: excretion patterns and effects of antiviral treatment., Boivin G, Aoki FY, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2009, 10.1016/j.jcv.2009.01.010
Ten years of human metapneumovirus research, Boivin, G., Rosa-Calatrava, M., Lina, B., Feuillet, F., Journal of Clinical Virology, 2012, 10.1016/j.jcv.2011.10.002
Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and management., Boivin G, Piret J, Antimicrobial agents and chemotherapy, 2010, 10.1128/aac.00615-10
Drug-resistant herpesviruses: should we look for them?, Boivin G, European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1998, 10.1007/bf01708615
Épidémiologie et impact clinique des nouveaux virus respiratoires., Boivin G, Hamelin ME, Revue des maladies respiratoires actualites, 2009, 10.1016/s1877-1203(09)75275-9
Protective role of CX3CR1 signalling in resident cells of the central nervous system during experimental herpes simplex virus encephalitis, Boivin, G., Gosselin, J., Piret, J., Canivet, C., Menasria, R., Journal of General Virology, 2017, 10.1099/jgv.0.000667
Longitudinal evaluation of herpes simplex virus DNA load during episodes of herpes labialis., Keays S, Booth T, Sergerie Y, Goyette N, Boivin G, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2006, 10.1016/j.jcv.2006.09.006
Quantification of human herpesvirus 8 by real-time PCR in blood fractions of AIDS patients with Kaposi's sarcoma and multicentric Castleman's disease., Routy JP, Maguigad M, Abed Y, Cloutier N, Côté S, Boivin G, Journal of medical virology, 2002, 10.1002/jmv.10217
Comparative evaluation of real-time PCR assays for detection of the human metapneumovirus., Boivin G, Abed Y, Côté S, Journal of clinical microbiology, 2003, 10.1128/jcm.41.8.3631-3635.2003
Both cerebral and hematopoietic deficiencies in CCR2 result in uncontrolled herpes simplex virus infection of the central nervous system in Mice, Boivin, G., Gosselin, J., Piret, J., Canivet, C., Menasria, R., PLoS ONE, 2016, 10.1371/journal.pone.0168034
A Review of Clinical Influenza A and B Infections With Reduced Susceptibility to Both Oseltamivir and Zanamivir., Boivin G, Abed Y, Open forum infectious diseases, 2017, 10.1093/ofid/ofx105
Disseminated herpes simplex virus type 1 primary infection in a healthy individual., Goyette N, Malette B, Boivin G, The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2009, 10.1155/2009/482407
Diagnosis of Viral Infections*, , Clinical Virology, Third Edition, 2009, 10.1128/9781555815981.ch13
International consensus guidelines on the management of cytomegalovirus in solid organ transplantation., Transplantation Society International CMV Consensus Group, Humar A, Allen U, Snydman DR, Chou S, Asberg A, Caliendo AM, Kumar D, Kotton CN, Transplantation, 2010, 10.1097/tp.0b013e3181cee42f
In vitro combinations of baloxavir acid and other inhibitors against seasonal influenza a viruses, Boivin, G., Baz, M., Abed, Y., Rosa-Calatrava, M., Terrier, O., Pizzorno, A., Padey, B., Checkmahomed, L., Viruses, 2020, 10.3390/v12101139
Development of a serological assay based on a synthetic peptide selected from the VP0 capsid protein for detection of human parechoviruses., Boivin G, Dagan R, Wolf D, Abed Y, Journal of clinical microbiology, 2007, 10.1128/jcm.02432-06
Importance of viral and bacterial infections in chronic obstructive pulmonary disease exacerbations., Boivin G, Barret B, Weiss K, Bourbeau J, Rouleau I, La Forge J, Lampron N, De Serres G, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2009, 10.1016/j.jcv.2009.07.010
Impact of the Baloxavir-Resistant Polymerase Acid I38T Substitution on the Fitness of Contemporary Influenza A(H1N1)pdm09 and A(H3N2) Strains, Boivin, G., Abed, Y., Baz, M., Venable, M.-C., Carbonneau, J., M'hamdi, Z., Checkmahomed, L., The Journal of infectious diseases, 2020, 10.1093/infdis/jiz418
Respiratory Syncytial Virus, Human Metapneumovirus, and the Parainfluenza Viruses, , Manual of Molecular and Clinical Laboratory Immunology, 7th Edition, 2006, 10.1128/9781555815905.ch79
In vitro susceptibility of geographically and temporally distinct Zika viruses to favipiravir and ribavirin, Boivin, G., Kobinger, G.P., Griffin, B.D., Goyette, N., Baz, M., Antiviral Therapy, 2017, 10.3851/IMP3180
Lack of emergence of cytomegalovirus UL97 mutations conferring ganciclovir (GCV) resistance following preemptive GCV therapy in allogeneic stem cell transplant recipients., Boivin G, Demers C, Beliveau C, Delage R, Belanger R, Roy J, Gilbert C, Antimicrobial agents and chemotherapy, 2001, 10.1128/aac.45.12.3669-3671.2001
Cytomegalovirus resistance in solid organ transplant recipients treated with intravenous ganciclovir or oral valganciclovir., Humar A, Hartmann A, Ives J, Asberg A, Pescovitz MD, Jardine AG, Rollag H, Goyette N, Boivin G, Antiviral therapy, 2009
Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its smallhydrophobic protein which plays adetrimental role during infection in mice, Boivin, G., Hamelin, M.E., Rosa-Calatrava, M., Pizzorno, A., Uyar, O., Cavanagh, M.H., Couture, C., Dubois, J., Le, V.B., PLoS Pathogens, 2019, 10.1371/journal.ppat.1007689
Optimization of Droplet Digital PCR from RNA and DNA extracts with direct comparison to RT-qPCR: Clinical implications for quantification of Oseltamivir-resistant subpopulations, Boivin, G., Shelton, D.N., Carbonneau, J., Taylor, S.C., Journal of Virological Methods, 2015, 10.1016/j.jviromet.2015.08.014
Human metapneumovirus infection in immunocompromised child., Boivin G, Abed Y, Emerging infectious diseases, 2008, 10.3201/eid1405.071459
The changing landscape of respiratory viruses contributing to respiratory hospitalizations: results from a hospital-based surveillance in Quebec, Canada, 2012-13 to 2021-22 (Preprint), Jeannot Dumaresq, Hugues Charest, Guy Boivin, Charles Frenette, Sara Carazo, Rachid Amini, Rodica Gilca, 2022, 10.2196/preprints.40792
Older Age and Frailty Are Associated With Higher Mortality but Lower Intensive Care Unit Admission Among Adults Admitted to Canadian Hospitals With COVID-19: A Report From the Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance Network, McNeil S, Loeb M, Trottier S, Ambrose A, MacKinnon-Cameron D, ElSherif M, Hatchette TF, McElhaney JE, Valiquette L, Boivin G, LeBlanc J, Godin J, Andrew M, 2021, 10.2139/ssrn.3844895
The distinguishing features of human metapneumovirus and respiratory syncytial virus., Boivin G, Papenburg J, Reviews in medical virology, 2010, 10.1002/rmv.651
Human metapneumovirus infections in hospitalized children., Déry P, Bergeron MG, Rochette L, Abed Y, Gilca R, Côté S, De Serres G, Boivin G, Emerging infectious diseases, 2003, 10.3201/eid0906.030017
The quest for a nanoparticle-based vaccine inducing broad protection to influenza viruses, Leclerc, D., Savard, P., Boivin, G., Russel, A., Garneau, C., Carignan, D., Laliberté-Gagné, M.-È., Baz, M., Bolduc, M., Nanomedicine: Nanotechnology, Biology, and Medicine, 2018, 10.1016/j.nano.2018.08.010
Strain-dependent impact of G and SH deletions provide new insights for live-attenuated HMPV vaccine development, Boivin, G., Rosa-Calatrava, M., Terrier, O., Hamelin, M.-È., Lina, B., Couture, C., Lavigne, S., Julien, T., Traversier, A., Carbonneau, J., Venable, M.-C., Uyar, O., De Lamballerie, C.N., Padey, B., Cavanagh, M.-H., Pizzorno, A., Dubois, J., Vaccines, 2019, 10.3390/vaccines7040164
Impact of potential permissive neuraminidase mutations on viral fitness of the H275Y oseltamivir-resistant influenza A(H1N1)pdm09 virus in vitro, in mice and in ferrets, Boivin, G., Rhéaume, C., Bouhy, X., Pizzorno, A., Abed, Y., Journal of Virology, 2014, 10.1128/JVI.02681-13
Novel method based on "en passant" mutagenesis coupled with a gaussia luciferase reporter assay for studying the combined effects of human cytomegalovirus mutations., Boivin G, Piret J, Drouot E, Journal of clinical microbiology, 2013, 10.1128/jcm.01275-13
Zika virus and impact on male fertility, Guy Boivin, Jocelyne Piret, Zika Virus Biology, Transmission, and Pathology, 2021, 10.1016/b978-0-12-820268-5.00026-2
Microglia are involved in phagocytosis and extracellular digestion during Zika virus encephalitis in young adult immunodeficient mice, Guy Boivin, Marie-Eve Tremblay, Julie Carbonneau, Nathalie Goyette, Marie-Christine Venable, Olus Uyar, Fernando González Ibáñez, Jocelyne Piret, Maude Bordeleau, William Enlow, Journal of Neuroinflammation, 2021, 10.1186/s12974-021-02221-z
Clinical development of letermovir and maribavir: Overview of human cytomegalovirus drug resistance, Boivin, G., Piret, J., Antiviral Research, 2019, 10.1016/j.antiviral.2019.01.011
Diagnosis of viral infections, Petric, M., Mazzulli, T., Boivin, G., Clinical Virology, 2016, 10.1128/9781555819439.ch15
Effect of foscarnet on quantities of cytomegalovirus and human immunodeficiency virus in blood of persons with AIDS., Martin-Munley SS, Eaton CA, Crumpacker CS, Shepp DH, Boivin G, Holm MA, Smith SA, Acosta EP, Henry WK, Erice A, Fletcher CV, Balfour HH, Antimicrobial agents and chemotherapy, 1996, 10.1128/aac.40.12.2721
Characterization of human cytomegalovirus (HCMV) UL97 mutations found in a valganciclovir/oral ganciclovir prophylactic trial by use of a bacterial artificial chromosome containing the HCMV genome., Boivin G, Covington E, Gilbert C, Martin M, The Journal of infectious diseases, 2006, 10.1086/505882
Both IRF3 and especially IRF7 play a key role to orchestrate an effective cerebral inflammatory response in a mouse model of herpes simplex virus encephalitis, Boivin, G., Gosselin, J., Piret, J., Lebel, M., Rhéaume, C., Canivet, C., Journal of NeuroVirology, 2018, 10.1007/s13365-018-0666-9
Emergence and prevalence of cytomegalovirus UL97 mutations associated with ganciclovir resistance in AIDS patients., Boivin G, Bergeron MG, Lalonde R, Toma E, Handfield J, Gilbert C, AIDS (London, England), 1998, 10.1097/00002030-199802000-00001
Highly reliable heterologous system for evaluating resistance of clinical herpes simplex virus isolates to nucleoside analogues., Boivin G, Papadopoulou B, Schmit I, Bestman-Smith J, Journal of virology, 2001, 10.1128/jvi.75.7.3105-3110.2001
Human respiratory syncytial virus and other viral infections in infants receiving palivizumab., De Serres G, Ouakki M, Carbonneau J, Frenette L, Caouette G, Boivin G, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2008, 10.1016/j.jcv.2007.11.012
Impact of R152K and R368K neuraminidase catalytic substitutions on in vitro properties and virulence of recombinant A(H1N1)pdm09 viruses, Boivin, G., Baz, M., Fage, C., Abed, Y., Tu, V., Antiviral Research, 2018, 10.1016/j.antiviral.2018.04.009
Human Respiratory Syncytial Virus-Induced Immune Signature of Infection Revealed by Transcriptome Analysis of Clinical Pediatric Nasopharyngeal Swab Samples, Rosa-Calatrava, M., Terrier, O., Legras-Lachuer, C., Boivin, G., Textoris, J., Roche, M., Hamelin, M.-E., Lina, B., Orcel, E., Carbonneau, J., Traversier, A., Julien, T., Padey, B., Dubois, J., Pizzorno, A., Nicolas De Lamballerie, C., Journal of Infectious Diseases, 2021, 10.1093/infdis/jiaa468
Differential impact of various substitutions at codon 715 in region II of HSV-1 and HCMV DNA polymerases, Boivin, G., Shi, R., Piret, J., Goyette, N., Zhu, X., Zarrouk, K., Antiviral Research, 2021, 10.1016/j.antiviral.2021.105046
Infection with human metapneumovirus predisposes mice to severe pneumococcal pneumonia., Boivin G, Bergeron MG, Bergeron Y, Gagnon C, Prince GA, Hamelin ME, Kukavica-Ibrulj I, Journal of virology, 2008, 10.1128/jvi.01123-08
Viral Interference between Respiratory Viruses., Boivin G, Piret J, Emerging infectious diseases, 2022, 10.3201/eid2802.211727
Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses., Boivin G, Hamelin ME, Simon P, Abed Y, Baz M, The Journal of infectious diseases, 2010, 10.1086/650464
Parenteral peramivir treatment for oseltamivir-resistant 2009 pandemic influenza a H1N1 viruses, Hernandez, J.E., Kodama, M., Yoshida, R., Boivin, G., Abed, Y., Journal of Infectious Diseases, 2011, 10.1093/infdis/jir610
A Candidate Therapeutic Monoclonal Antibody Inhibits Both HRSV and HMPV Replication in Mice, Gary P. Kobinger, Marc-André D’Aoust, Guy Boivin, Marie-Ève Ouellet, Pierre-Olivier Lavoie, Liva Checkmahomed, Marie-Christine Venable, Julie Carbonneau, Marie-Eve Hamelin, Hugues Fausther-Bovendo, Biomedicines, 2022, 10.3390/biomedicines10102516
The REinfection in COVID-19 Estimation of Risk (RECOVER) study: Reinfection and serology dynamics in a cohort of Canadian healthcare workers, Caroline Quach, Gaston De Serres, Jacques Corbeil, Vladimir Gilca, Sabryna Nantel, Benoîte Bourdin, Kelsey Adams, Fazia Tadount, Marie-Ève Hamelin, Matthew P. Cheng, Patrice Savard, Hélène Decaluwe, Deirde McCormack, Yves Longtin, Guy Boivin, Étienne Racine, 2022, 10.1101/2022.02.10.22269967
Phenotypic and genotypic characterization of acyclovir-resistant varicella-zoster viruses isolated from persons with AIDS., Balfour HH, Biron KK, Talarico CL, Pedneault L, Edelman CK, Boivin G, The Journal of infectious diseases, 1994, 10.1093/infdis/170.1.68
Effects of different adjuvants in the context of intramuscular and intranasal routes on humoral and cellular immune responses induced by detergent-split A/H3N2 influenza vaccines in mice, Boivin, G., Papadopoulou, B., Mallett, C., Hamelin, M.-E., Lanteigne, A.-M., Plante, M., Tribout-Jover, P., Zekki, H., Samant, M., Baz, M., Clinical and Vaccine Immunology, 2012, 10.1128/CVI.05441-11
Influenza vaccine oculorespiratory syndrome incidence is reduced in HIV., Canadian Institutes of Health Research-Canadian HIV Trials Network (CTN) Influenza Vaccine Research Group, Thorne A, Cooper C, Vaccine, 2011, 10.1016/j.vaccine.2011.08.066
Standardization of Hemagglutination Inhibition Assay for Influenza Serology Allows for High Reproducibility between Laboratories, Hatchette, T.F., LeBlanc, J.J., McNeil, S.A., Warhuus, M., Li, Y., Boivin, G., Tang, P., Brewer, A., Ward, B.J., Zacour, M., Clinical and Vaccine Immunology, 2016, 10.1128/CVI.00613-15
Effect of pretreatment with toll-like receptor agonists in a mouse model of herpes simplex virus type 1 encephalitis., Boivin G, Rivest S, Sergerie Y, Boivin N, The Journal of infectious diseases, 2008, 10.1086/590671
Droplet Digital PCR and Immunohistochemistry Techniques to Detect Zika Virus in the Central Nervous System of Mice, Boivin, G., Piret, J., Enlow, W., Methods in Molecular Biology, 2020, 10.1007/978-1-0716-0581-3_4
Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice., Boivin G, Kinkead R, Gomez AM, Prince GA, Hamelin ME, The Journal of infectious diseases, 2006, 10.1086/504262
Contrasting effects on ganciclovir susceptibility and replicative capacity of two mutations at codon 466 of the human cytomegalovirus UL97 gene., Boivin G, Goyette N, Martin M, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2010, 10.1016/j.jcv.2010.08.008
Canadian consensus guidelines for the management of cytomegalovirus disease in HIV/AIDS., Walmsley S, Shafran SD, Phillips P, Lindley JI, Klein AH, Hopkins JJ, Hodge WG, Deschênes J, Boivin G, Lalonde RG, The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2004, 10.1155/2004/369390
The nonstructural NS1 protein of influenza viruses modulates TP53 splicing through host factor CPSF4, Terrier, O., Rosa-Calatrava, M., Boivin, G., Marcel, V., Bourdon, J.-C., Lina, B., Padey, B., Julien, T., Traversier, A., Dubois, J., Journal of Virology, 2019, 10.1128/JVI.02168-18
The Val430Ile neuraminidase (NA) substitution, identified in influenza B virus isolates, impacts the catalytic 116Arg residue causing reduced susceptibility to NA inhibitors, Boivin, G., Lague, P., Carbonneau, J., Begin, G., Checkmahomed, L., Fage, C., Abed, Y., Antiviral Research, 2019, 10.1016/j.antiviral.2019.104561
Cross-reactive and vaccine-induced antibody to an emerging swine-origin variant of influenza A virus subtype H3N2 (H3N2v)., Li Y, Boivin G, Petric M, Bastien N, Li G, Gardy JL, Sabaiduc S, Dionne M, Scheifele DW, Gilca V, Purych D, De Serres G, Janjua NZ, Skowronski DM, The Journal of infectious diseases, 2012, 10.1093/infdis/jis500
Intravenous ciprofloxacin disposition in obesity., LeBel M, Sörgel F, Boivin G, Kinzig M, Allard S, Clinical pharmacology and therapeutics, 1993, 10.1038/clpt.1993.162
Evaluation of recombinant 2009 pandemic influenza A (H1N1) viruses harboring zanamivir resistance mutations in mice and ferrets., Boivin G, Bouhy X, Rhéaume C, Abed Y, Pizzorno A, Antimicrobial agents and chemotherapy, 2013, 10.1128/aac.02269-12
Identification and evaluation of a highly effective fusion inhibitor for human metapneumovirus., Boivin G, Prince GA, Hamelin ME, Deffrasnes C, Antimicrobial agents and chemotherapy, 2007, 10.1128/aac.00793-07
Mutations in the fusion protein heptad repeat domains of human metapneumovirus impact on the formation of syncytia, Boivin, G., Rosa-Calatrava, M., Shi, R., Lina, B., Hamelin, M.È., Terrier, O., Cavanagh, M.-H., Dubois, J., Journal of General Virology, 2017, 10.1099/jgv.0.000796
Streptococcus pneumoniae serotype 3 is masking PCV13-mediated herd immunity in Canadian adults hospitalized with community acquired pneumonia: A study from the Serious Outcomes Surveillance (SOS) Network of the Canadian immunization research Network (CIRN), McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Semret, M., McGeer, A., McCarthy, A.E., Loeb, M., Johnstone, J., Green, K., Bowie, W., Boivin, G., Andrew, M.K., Demczuk, W., Martin, I., Gillis, H.D., Lang, A.L.S., Hatchette, T.F., Ambrose, A., MacKinnon-Cameron, D., Ye, L., ElSherif, M., LeBlanc, J.J., Vaccine, 2019, 10.1016/j.vaccine.2019.05.003
Role of picornaviruses in flu-like illnesses of adults enrolled in an oseltamivir treatment study who had no evidence of influenza virus infection., Ward P, Groen J, Jackson HC, Gaudreau A, Osterhaus AD, Boivin G, Journal of clinical microbiology, 2002, 10.1128/jcm.40.2.330-334.2002
Detection of human metapneumovirus antigens in nasopharyngeal aspirates using an enzyme immunoassay., Boivin G, Kukavica-Ibrulj I, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2008, 10.1016/j.jcv.2008.09.011
Predictive risk factors for hospitalization and response to colchicine in patients with COVID-19, Guy Boivin, Marie-Pierre Dubé, Nadia Bouabdallaoui, Marie-Claude Guertin, Mariève Cossette, Jean-Claude Tardif, International Journal of Infectious Diseases, 2022, 10.1016/j.ijid.2022.01.020
Oseltamivir-resistant pandemic A/H1N1 virus is as virulent as its wild-type counterpart in mice and ferrets., Boivin G, Kobinger GP, Schumer G, Mallett C, Plante M, Bellerose N, Beaulieu E, Joubert P, Couture C, Abed Y, Baz M, Hamelin ME, PLoS pathogens, 2010, 10.1371/journal.ppat.1001015
Human metapneumovirus: a ubiquitous and long-standing respiratory pathogen., Boivin G, Hamelin ME, The Pediatric infectious disease journal, 2005, 10.1097/01.inf.0000188158.27840.7c
Susceptibility of recent Canadian influenza A and B virus isolates to different neuraminidase inhibitors., Goyette N, Boivin G, Antiviral research, 2002, 10.1016/s0166-3542(01)00219-4
The I222V neuraminidase mutation has a compensatory role in replication of an oseltamivir-resistant influenza virus A/H3N2 E119V mutant., Boivin G, Beauchemin CA, Abed Y, Bouhy X, Holder BP, Simon P, Journal of clinical microbiology, 2010, 10.1128/jcm.01732-10
Human metapneumovirus: a new player among respiratory viruses., Boivin G, Abed Y, Hamelin ME, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, 10.1086/382536
Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model., Boivin G, Riteau B, Vergnolle N, Seidah NG, Prat A, Susan-Resiga D, Kim W, Couture C, Lavigne S, Rhéaume C, Hamelin MÈ, Aerts L, PloS one, 2013, 10.1371/journal.pone.0072529
Opposite effect of two cytomegalovirus DNA polymerase mutations on replicative capacity and polymerase activity., Boivin G, Lin SX, Azzi A, Martin M, Antiviral therapy, 2010, 10.3851/imp1565
Reply, Boivin G, The Journal of infectious diseases, 2000, 10.1086/315668
Syncytium formation and HIV-1 replication are both accentuated by purified influenza and virus-associated neuraminidase., Tremblay MJ, Goyette N, Boivin G, Sato S, Barbeau B, Sun J, The Journal of biological chemistry, 2002, 10.1074/jbc.m110764200
Compartmentalization of a Multidrug-Resistant Cytomegalovirus UL54 Mutant in a Stem Cell Transplant Recipient with Encephalitis, Boivin, G., Shi, R., Alain, S., Goyette, N., Kaiser, L., Masouridi-Levrat, S., Giannotti, F., Hantz, S., Pham, V.D., Schibler, M., Piret, J., Journal of Infectious Diseases, 2019, 10.1093/infdis/jiz298
Human parainfluenza type 4 infections, Canada., Boivin G, Bergeron MG, Moisan D, Leblanc E, Dionne N, Vachon ML, Emerging infectious diseases, 2006, 10.3201/eid1211.060196
Human parechovirus 3 and neonatal infections., Boucher FD, Abed Y, Boivin G, Emerging infectious diseases, 2005, 10.3201/eid1101.040606
Influenzavirus infection is a primary cause of febrile respiratory illness in HIV-infected adults, despite vaccination., Boivin G, Coté S, DelBalso L, Lu Y, Klein MB, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, 10.1086/518986
Prophylactic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H274Y neuraminidase mutation., Boivin G, Simon P, Abed Y, Antimicrobial agents and chemotherapy, 2010, 10.1128/aac.01681-09
WU polyomavirus in children, Canada., Boivin G, Wang D, Abed Y, Emerging infectious diseases, 2007, 10.3201/eid1312.070909
Frailty hinders recovery from influenza and acute respiratory illness in older adults, Andrew, M.K., Webster, D., Semret, M., Powis, J., Poirier, A., McGeer, A., Boivin, G., Bowie, W., LeBlanc, J., Hatchette, T.F., Loeb, M., McNeil, S.A., McElhaney, J.E., Godin, J., Lees, C., Journal of Infectious Diseases, 2020, 10.1093/infdis/jiaa092
Viral interference between severe acute respiratory syndrome coronavirus 2 and influenza A viruses, Guy Boivin, Nathalie Goyette, Mathilde Hénaut, Julie Carbonneau, Jocelyne Piret, Shella Gilbert-Girard, 2024, 10.1101/2024.02.02.578538
Interim estimates of 2013/14 influenza clinical severity and vaccine effectiveness in the prevention of laboratory-confirmed influenza-related hospitalisation, Canada, February 2014, McGeer, A., Ye, L., Webster, D., Valiquette, L., Trottier, S., Stiver, G., Smyth, D., Smith, S., Semret, M., Richardson, D., Powis, J., Poirier, M., McCarthy, A.E., MacKinnon-Cameron, D., McElhaney, J., Loeb, M., Light, B., Lagacã-Wiens, P., Langley, J.M., Katz, K., Ibarguchi, B., Halperin, S., Haguinet, F., Green, K., ElSherif, M., Diaz-Mitoma, F., Bowie, W.R., Boivin, G., Ambrose, A., Leblanc, J., Hatchette, T.F., Andrew, M., Shinde, V., McNeil, S.A., Eurosurveillance, 2014, 10.2807/1560-7917.ES2014.19.9.20729
Influenza drug resistance., Boivin G, Abed Y, Pizzorno A, Seminars in respiratory and critical care medicine, 2011, 10.1055/s-0031-1283281
The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-organ Transplantation., The Transplantation Society International CMV Consensus Group, Humar A, Danziger-Isakov L, Chou S, Huprikar S, Caliendo AM, Kumar D, Kotton CN, Transplantation, 2018, 10.1097/tp.0000000000002191
Human metapneumovirus genetic variability, South Africa., Madhi SA, Klugman KP, Boivin G, van Niekerk N, Abed Y, Ludewick HP, Emerging infectious diseases, 2005, 10.3201/eid1107.050050
Clinical impact of ganciclovir-resistant cytomegalovirus infections in solid organ transplant patients., Covington E, Humar A, Gilbert C, Goyette N, Boivin G, Transplant infectious disease : an official journal of the Transplantation Society, 2005, 10.1111/j.1399-3062.2005.00112.x
Antiviral susceptibilities and analysis of UL97 and DNA polymerase sequences of clinical cytomegalovirus isolates from immunocompromised patients., Chou S, Boivin G, Hanson MN, Sannerud KJ, Balfour HH, Pérez JL, Gil-Roda C, Erice A, The Journal of infectious diseases, 1997, 10.1086/516446
OVX836 a recombinant nucleoprotein vaccine inducing cellular responses and protective efficacy against multiple influenza A subtypes, Hill, F., Marvel, J., Rosa-Calatrava, M., Leverrier, Y., Le Vert, A., Nicolas, F., Hamelin, M.-E., Boivin, G., Lina, B., Pérez-Vargas, J., Haller, M., Bouley, J., Djebali, S., Pizzorno, A., Del Campo, J., npj Vaccines, 2019, 10.1038/s41541-019-0098-4
Emergence of oseltamivir-resistant pandemic H1N1 virus during prophylaxis., Boivin G, Hamelin ME, Bouhy X, Papenburg J, Abed Y, Baz M, The New England journal of medicine, 2009, 10.1056/nejmc0910060
[The emergence of viruses resistant to antiviral agents: a new challenge]., Boivin G, L'union medicale du Canada, 1993
Detection of ganciclovir resistance mutations quantitation of cytomegalovirus (CMV) DNA in leukocytes of patients with fatal disseminated CMV disease., Jordan MC, Erice A, Quirk MR, Chou S, Boivin G, The Journal of infectious diseases, 1996, 10.1093/infdis/173.3.523
Quantitation of human cytomegalovirus glycoprotein H gene in cells using competitive PCR and a rapid fluorescence-based detection system., Jordan MC, St-Cyr SM, Quirk MR, Olson CA, Boivin G, Journal of virological methods, 1995, 10.1016/0166-0934(94)00128-4
Oseltamivir-zanamivir combination therapy is not superior to zanamivir monotherapy in mice infected with influenza A(H3N2) and A(H1N1)pdm09 viruses, Boivin, G., Rhéaume, C., Abed, Y., Pizzorno, A., Antiviral Research, 2014, 10.1016/j.antiviral.2014.02.017
Protease-activated receptor 1 inhibition protects mice against thrombin-dependent respiratory syncytial virus and human metapneumovirus infections, Boivin, G., Hamelin, M.-È., Rhéaume, C., Jandrot-Perrus, M., Couture, C., Alessi, M.-C., Riteau, B., Lê, V.B., British Journal of Pharmacology, 2018, 10.1111/bph.14084
Artesunate demonstrates in vitro synergism with several antiviral agents against human cytomegalovirus., Boivin G, Piret J, Drouot E, Antiviral therapy, 2016, 10.3851/imp3028
Engineering of live chimeric vaccines against human metapneumovirus, Boivin, G., Hamelin, M.-È., Makowska, D.O., Pathogens, 2020, 10.3390/pathogens9020135
The cost-effectiveness and value of information of three influenza vaccination dosing strategies for individuals with human immunodeficiency virus., CIHR Canadian HIV Trials Network Influenza Vaccine Research Group, Cooper C, Anis AH, Sun H, Sharif B, Nosyk B, PloS one, 2011, 10.1371/journal.pone.0027059
The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness, Boivin, G., Lagüe, P., Fage, C., Carbonneau, J., Barbeau, X., Abed, Y., Tu, V., Antiviral Research, 2017, 10.1016/j.antiviral.2016.11.007
Drug susceptibility and replicative capacity of multidrug-resistant recombinant human cytomegalovirus harboring mutations in UL56 and UL54 genes, Boivin, G., Goyette, N., Piret, J., Antimicrobial Agents and Chemotherapy, 2017, 10.1128/AAC.01044-17
Antiviral Drugs Against Herpesviruses, Guy Boivin, Jocelyne Piret, Antiviral Drug Discovery and Development, 2021, 10.1007/978-981-16-0267-2_1
Permissive changes in the neuraminidase play a dominant role in improving the viral fitness of oseltamivir-resistant seasonal influenza A(H1N1) strains, Boivin, G., Bouhy, X., Pizzorno, A., Abed, Y., Antiviral Research, 2015, 10.1016/j.antiviral.2014.12.006
Human cytomegalovirus resistance to antiviral drugs., Boivin G, Gilbert C, Antimicrobial agents and chemotherapy, 2005, 10.1128/aac.49.3.873-883.2005
Management and prevention of herpes zoster: A Canadian perspective., Patrick DM, Elliott CT, Jovey R, Boivin G, The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2010, 10.1155/2010/178036
Human metapneumovirus, the point ten years after its discovery. Genomic characteristics, virological and therapeutic advances,Le métapneumovirus humain, le point dix années après sa découverte. Caractéristiques génomiques, virologiques et avancées thérapeutiques, Boivin, G., Rosa-Calatrava, M., Feuillet, F., Virologie, 2011, 10.1684/vir.2011.0411
Fitness of influenza A and B viruses with reduced susceptibility to baloxavir: A mini-review, Boivin, G., Saim-Mamoun, A., Abed, Y., Reviews in Medical Virology, 2021, 10.1002/rmv.2175
Prolonged excretion of amantadine-resistant influenza a virus quasi species after cessation of antiviral therapy in an immunocompromised patient., Bernatchez H, Goyette N, Boivin G, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, 10.1086/338870
Immunogenicity is not improved by increased antigen dose or booster dosing of seasonal influenza vaccine in a randomized trial of HIV infected adults., CIHR Canadian HIV Trials Network Influenza Vaccine Research Group, Walmsley S, Singer J, Halperin S, Zubyk W, Shafran S, Haase D, Boivin G, Conway B, Klein M, Thorne A, Cooper C, PloS one, 2011, 10.1371/journal.pone.0017758
Antibiotic use in children is not influenced by the result of rapid antigen detection test for the respiratory syncytial virus., Déry P, Boivin G, De Serres G, Côté S, Gilca R, Thibeault R, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2007, 10.1016/j.jcv.2007.04.013
Host and viral factors affecting clinical performance of a rapid diagnostic test for respiratory syncytial virus in hospitalized children., Boivin G, De Serres G, Buckeridge DL, Papenburg J, The Journal of pediatrics, 2013, 10.1016/j.jpeds.2013.03.067
Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade, Boivin, G., Hamelin, M.-T., De Serres, G., Williams, J.V., Bergeron, M.G., Isabel, S., Carbonneau, J., Papenburg, J., Journal of Clinical Virology, 2013, 10.1016/j.jcv.2013.08.029
Effectiveness of Influenza Vaccination on Hospitalizations and Risk Factors for Severe Outcomes in Hospitalized Patients With COPD, Taylor, G., Smith, S., Poirier, A., Light, B., Lagace-Wiens, P., McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Smyth, D., Shinde, V., Semret, M., Richardson, D., Powis, J., McGeer, A., McElhaney, J.E., McCarthy, A., MacKinnon-Cameron, D., Loeb, M., LeBlanc, J., Langley, J.M., Katz, K., Johnstone, J., Ibarguchi, B., Halperin, S.A., Haguinet, F., Green, K., ElSherif, M., Dos Santos, G., Chit, A., Bowie, W., Boivin, G., Ambrose, A., Andrew, M.K., Hatchette, T., Ye, L., Li, L., Mulpuru, S., Chest, 2019, 10.1016/j.chest.2018.10.044
A reverse genetics study of resistance to neuraminidase inhibitors in an influenza A/H1N1 virus., Boivin G, Goyette N, Abed Y, Antiviral therapy, 2004
Molecular evolution of respiratory syncytial virus fusion gene, Canada, 2006-2010., Boivin G, De Serres G, Bergeron MG, Corbeil J, Déry P, Paes BA, Ohoumanne N, Bouhy X, Isabel S, Hamelin MÈ, Carbonneau J, Papenburg J, Emerging infectious diseases, 2012, 10.3201/eid1801.110515
The impact of prior season vaccination on subsequent influenza vaccine effectiveness to prevent influenza-related hospitalizations over 4 influenza seasons in Canada, McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Smyth, D., Shinde, V., Sharma, R., Semret, M., Richardson, D., Powis, J., McGeer, A., McElhaney, J.E., McCarthy, A., Mackinnon-Cameron, D., Loeb, M., Leblanc, J., Katz, K., Haguinet, F., Green, K., Elsherif, M., Dos Santos, G., Bowie, W., Boivin, G., Ambrose, A., Hatchette, T.F., Ye, L., Andrew, M.K., Nichols, M.K., Clinical Infectious Diseases, 2019, 10.1093/cid/ciy1009
Age-stratified burden of pneumococcal community acquired pneumonia in hospitalised Canadian adults from 2010 to 2015, McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Semret, M., McGeer, A., McCarthy, A., Loeb, M., Johnstone, J., Green, K., Bowie, W., Boivin, G., Andrew, M.K., Laferriere, C., Demczuk, W.H., Martin, I., Gillis, H.D., Lang, A.L.S., Hatchette, T.F., Ambrose, A., Mackinnon-Cameron, D., Ye, L., Elsherif, M., Leblanc, J., BMJ Open Respiratory Research, 2020, 10.1136/bmjresp-2019-000550
Combination therapy with oseltamivir and favipiravir delays mortality but does not prevent oseltamivir resistance in immunodeficient mice infected with pandemic A(H1N1) influenza virus, Boivin, G., Cavanagh, M.-H., Rhéaume, C., Carbonneau, J., Baz, M., Viruses, 2018, 10.3390/v10110610
Delayed but not early glucocorticoid treatment protects the host during experimental herpes simplex virus encephalitis in mice., Rivest S, Gosselin D, Boivin G, Sergerie Y, The Journal of infectious diseases, 2007, 10.1086/511987
Multiplex real-time PCR assay for detection of influenza and human respiratory syncytial viruses., Bergeron MG, De Serres G, Déry P, Côté S, Boivin G, Journal of clinical microbiology, 2004, 10.1128/jcm.42.1.45-51.2004
Diagnosis of herpesvirus infections of the central nervous system., Boivin G, Herpes : the journal of the IHMF, 2004
The Changing Landscape of Respiratory Viruses Contributing to Hospitalizations: Results from an active Hospital-based Surveillance in Quebec, Canada, 2012-13 to 2022-23 (Preprint), Jeannot Dumaresq, Hugues Charest, Guy Boivin, Charles Frenette, Radhouene Doggui, Sara Carazo, Rachid Amini, Rodica Gilca, JMIR Public Health and Surveillance, 2022, 10.2196/40792
The H275Y neuraminidase mutation of the pandemic A/H1N1 influenza virus lengthens the eclipse phase and reduces viral output of infected cells, potentially compromising fitness in ferrets., Beauchemin CA, Boivin G, Abed Y, Holder BP, Pinilla LT, Journal of virology, 2012, 10.1128/jvi.07244-11
Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial., COLCORONA Investigators, Denault A, Dupuis J, Audet S, Verret L, da Luz P, Lopez-Sendon J, Pillinger MH, Shah B, L'Allier PL, Gaudet D, Bouabdallaoui N, Tardif JC, The Lancet. Respiratory medicine, 2021, 10.1016/s2213-2600(21)00222-8
The combination of valacyclovir with an anti-TNF alpha antibody increases survival rate compared to antiviral therapy alone in a murine model of herpes simplex virus encephalitis, Boivin, G., Rivest, S., Piret, J., Menasria, R., Boivin, N., Antiviral Research, 2013, 10.1016/j.antiviral.2013.10.007
Resource utilization and cost of influenza requiring hospitalization in Canadian adults: A study from the serious outcomes surveillance network of the Canadian Immunization Research Network, McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Stiver, G., Smyth, D., Smith, S., Semret, M., Sharma, R., Richardson, D., Powis, J., Poirier, A., McGeer, A., McElhaney, J., McCarthy, A., MacKinnon-Cameron, D., Loeb, M., Leblanc, J., Katz, K., Johnstone, J., Green, K., ElSherif, M., Bowie, W., Boivin, G., Hatchette, T., Andrew, M.K., Ambrose, A., Goeree, R., Thommes, E., Hux, M., Noorduyn, S.G., Ye, L., Ng, C., Influenza and other Respiratory Viruses, 2018, 10.1111/irv.12521
Incidence of cytomegalovirus UL97 and UL54 amino acid substitutions detected after 100 or 200 days of valganciclovir prophylaxis., Elston R, Farhan M, Ives J, Goyette N, Boivin G, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2012, 10.1016/j.jcv.2011.12.019
Human metapneumovirus, Peru., Boivin G, Abed Y, McCarthy T, Lebeck MG, Olson J, Neville JS, Sanchez JL, Setterquist SF, Capuano AW, Gray GC, Emerging infectious diseases, 2006, 10.3201/eid1202.051133
Acyclovir susceptibilities of herpes simplex virus strains isolated from solid organ transplant recipients after acyclovir or ganciclovir prophylaxis., Balfour HH, Dunn DL, Crane DD, Erice A, Boivin G, Antimicrobial agents and chemotherapy, 1993, 10.1128/aac.37.2.357
Impact of Amino Acid Substitutions in Region II and Helix K of HSV-1 and HCMV DNA Polymerases on Resistance to Foscarnet., Boivin G, Shi R, Piret J, Goyette N, Pham VD, Zhu X, Zarrouk K, Antimicrobial agents and chemotherapy, 2021, 10.1128/aac.00390-21
Hypersusceptibility of human cytomegalovirus to foscarnet induced by mutations in helices K and P of the viral DNA polymerase, Boivin, G., Shi, R., Piret, J., Pham, V.D., Zarrouk, K., Antimicrobial Agents and Chemotherapy, 2020, 10.1128/AAC.01910-19
Assessing the in vitro fitness of an oseltamivir-resistant seasonal A/H1N1 influenza strain using a mathematical model., Boivin G, Beauchemin CA, Bouhy X, Abed Y, Liao LE, Simon P, Holder BP, PloS one, 2011, 10.1371/journal.pone.0014767
Comparative evaluation of three serological methods for detection of human herpesvirus 8-specific antibodies in Canadian allogeneic stem cell transplant recipients., Boivin G, Roy J, Abed Y, Sergerie Y, Journal of clinical microbiology, 2004, 10.1128/jcm.42.6.2663-2667.2004
Evaluation of pre- and post-fusion Human metapneumovirus F proteins as subunit vaccine candidates in mice, Boivin, G., Hamelin, M.-È., Guarné, A., Couture, C., Lavigne, S., Rhéaume, C., Venable, M.-C., Carbonneau, J., Shen, Y., Pilaev, M., Vaccine, 2020, 10.1016/j.vaccine.2020.01.047
Rapid antiviral effect of inhaled zanamivir in the treatment of naturally occurring influenza in otherwise healthy adults., Trottier S, Wagner A, Aoki F, Hardy I, Goyette N, Boivin G, The Journal of infectious diseases, 2000, 10.1086/315392
Characterization of the DNA polymerase and thymidine kinase genesof herpes simplex virus isolates from AIDS patients in whom acyclovirand foscarnet therapy sequentially failed., Boivin G, Schmit I, The Journal of infectious diseases, 1999, 10.1086/314900
The recruitment of peripheral blood leukocytes to the brain is delayed in susceptible BALB/c compared to resistant C57BL/6 mice during herpes simplex virus encephalitis, Boivin, G., Piret, J., Rhéaume, C., Uyar, O., Canivet, C., Journal of NeuroVirology, 2019, 10.1007/s13365-019-00730-5
Contagious period for pandemic (H1N1) 2009., Boivin G, Charest H, Couillard M, Bourgault A, Li Y, Carbonneau J, Boulianne N, Flamand L, Skowronski D, Quach C, Hamelin ME, Rouleau I, De Serres G, Emerging infectious diseases, 2010, 10.3201/eid1605.091894
Novel antiviral compounds and combination therapy for influenza viruses,Nouveaux composés antiviraux et thérapie combinée contre les virus influenza, Lina, B., Rosa-Calatrava, M., Boivin, G., Virologie, 2019, 10.1684/vir.2019.0802
Quantitation of cytomegalovirus (CMV) DNA in leukocytes of human immunodeficiency virus-infected subjects with and without CMV disease by using PCR and the SHARP Signal Detection System., Bergeron MG, Lazar JG, Lalonde R, Toma E, Murray G, Handfield J, Boivin G, Journal of clinical microbiology, 1997, 10.1128/jcm.35.2.525-526.1997
Genetics of symptom remission in outpatients with COVID-19, Tardif, J.-C., Busseuil, D., Boivin, G., Hussin, J., L’Allier, P.L., Gaudet, D., Nozza, A., Bassevitch, Z., Marchand, R., Bouabdallaoui, N., de Denus, S., Guertin, M.-C., Chabot-Blanchet, M., Cossette, M., Chicoine, L.-M., Savard, C., Goulet, E., Choi, J., Lousky, J., Dedelis, E., Valois, D., Dubois, A., Mongrain, I., Legault, M.-A., Sandoval, J., Sun, M., Provost, S., Asselin, G., Oussaïd, E., Lemieux Perreault, L.-P., Barhdadi, A., Lemaçon, A., Dubé, M.-P., Scientific Reports, 2021, 10.1038/s41598-021-90365-6
Structural Insight into NS5 of Zika Virus Leading to the Discovery of MTase Inhibitors, Lin, S.-X., Boivin, G., Baz, M., Stephen, P., Journal of the American Chemical Society, 2016, 10.1021/jacs.6b10399
Risk factors for hospitalization and severe outcomes of 2009 pandemic H1N1 influenza in Quebec, Canada, Skowronski, D.M., Boivin, G., Dionne, M., Fortin, E., Douville-Fradet, M., Papenburg, J., Ouhoummane, N., Boulianne, N., de Serres, G., Gilca, R., Influenza and other Respiratory Viruses, 2011, 10.1111/j.1750-2659.2011.00204.x
Clearance of cytomegalovirus viremia after initiation of highly active antiretroviral therapy., LeBlanc RP, Boivin G, The Journal of infectious diseases, 2000, 10.1086/315358
Reinfection with SARS-CoV-2 in a patient undergoing chemotherapy for lymphoma: Case report, Guy Boivin, Martin A Smith, Marieke Rozendaal, Antoine Chiasson, Julie Carbonneau, Marie-Ève Hamelin, Shawn M Simpson, Marie Gourdeau, Julie Bestman-Smith, Florence Côté, Official Journal of the Association of Medical Microbiology and Infectious Disease Canada, 2022, 10.3138/jammi-2021-0036
Resistance of Herpesviruses to Antiviral Agents, Guy Boivin, Jocelyne Piret, William L. Drew, Antimicrobial Resistance in the 21st Century, 2018, 10.1007/978-3-319-78538-7_8
Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets, Boivin, G., Mallett, C., Hamelin, M.-E., Carbonneau, J., Dubé, K., Joly, M.-H., Bouhy, X., Beaulieu, E., Abed, Y., Ann, J., Influenza and other Respiratory Viruses, 2016, 10.1111/irv.12356
Human cytomegalovirus glycoprotein B genotypes in blood of AIDS patients: lack of association with either the viral DNA load in leukocytes or presence of retinitis., Boivin G, Bergeron MG, Lalonde R, Toma E, Handfield J, Gilbert C, Journal of medical virology, 1999, 10.1002/(sici)1096-9071(199909)59:1<98::aid-jmv16>3.0.co;2-a
A Cluster of Three Cases of Hantavirus Pulmonary Syndrome among Canadian Military Personnel., Loo VG, Boivin G, Vinh DC, Bestman-Smith J, Beaudoin MC, Longtin J, Nguyen TT, Parkes LO, The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2016, 10.1155/2016/2757969
Reduced susceptibility to neuraminidase inhibitors in influenza b isolate, Canada, Boivin, G., Vinh, D.C., Papenburg, J., Carbonneau, J., Lagüe, P., Fage, C., Abed, Y., Emerging Infectious Diseases, 2019, 10.3201/EID2504.181554
Treatment of respiratory virus infections., Boivin G, Abed Y, Antiviral research, 2006, 10.1016/j.antiviral.2006.01.006
Characterization of cellular transcriptomic signatures induced by different respiratory viruses in human reconstituted airway epithelia, Rosa-Calatrava, M., Terrier, O., Boivin, G., Lina, B., Legras-Lachuer, C., Traversier, A., Bouveret, M., Padey, B., Julien, T., Dubois, J., Pizzorno, A., Nicolas de Lamballerie, C., Scientific Reports, 2019, 10.1038/s41598-019-48013-7
Herpes simplex encephalitis in adult patients with MASP-2 deficiency, Bochud, P.-Y., Boivin, G., Rivolta, C., Fellmann, F., Erard, V., Bihl, T., Meylan, P., Menasria, R., Michielin, O., Zoete, V., Collinet, E., Quinodoz, M., Piret, J., Bibert, S., PLoS Pathogens, 2019, 10.1371/journal.ppat.1008168
Evaluation of serological diagnostic methods for the 2009 pandemic influenza A (H1N1) virus., Boivin G, De Serres G, Rouleau I, Ouakki M, Carbonneau J, Rhéaume C, Hamelin MÈ, Baz M, Papenburg J, Clinical and vaccine immunology : CVI, 2011, 10.1128/cvi.00449-10
Adjuvanted inactivated influenza A(H3N2) vaccines induce stronger immunogenicity in mice and confer higher protection in ferrets than unadjuvanted inactivated vaccines, Boivin, G., Papadopoulou, B., Hamelin, M.-E., Mallett, C., Morasse, A., Beaulieu, E., Dumas, C., Rheaume, C., Samant, M., Ann, J., Vaccine, 2014, 10.1016/j.vaccine.2014.08.029
Design and validation with influenza a virus of an aerosol transmission chamber for ferrets, Duchaine, C., Boivin, G., Girard, M., Checkmahomed, L., Carbonneau, J., Rhéaume, C., Lévesque, A., Verreault, D., Hamelin, M.-È., Turgeon, N., International Journal of Environmental Research and Public Health, 2019, 10.3390/ijerph16040609
Cell culture systems to study human herpesvirus 6A/B chromosomal integration, Flamand, L., Kaufer, B.B., Boivin, G., Carbonneau, J., Mori, Y., Jerome, K.R., Hall-Sedlak, R., Collin, V., Gilbert-Girard, S., Wallaschek, N., Dubuc, I., Gravel, A., Journal of Virology, 2017, 10.1128/JVI.00437-17
Case study: rapid emergence of a cytomegalovirus UL97 mutant in a heart-transplant recipient on pre-emptive ganciclovir therapy., Boivin G, LeBlanc MH, Gilbert C, Herpes : the journal of the IHMF, 2001
A case of ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with AIDS: longitudinal molecular analysis of the CMV viral load and viral mutations in blood compartments., Bergeron MG, Goyette N, Handfield J, Morissette M, Gilbert C, Boivin G, AIDS (London, England), 1997, 10.1097/00002030-199707000-00005
Burden of vaccine-preventable pneumococcal disease in hospitalized adults: A Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) network study, McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Stiver, G., Semret, M., Moraca, S., McGeer, A., McCarthy, A., Loeb, M., Johnstone, J., Green, K., Bowie, W., Boivin, G., Andrew, M.K., Martin, I., Gillis, H., Lang, A.L., Hatchette, T.F., Ambrose, A., Li, L., MacKinnon-Cameron, D., Ye, L., ElSherif, M., LeBlanc, J.J., Vaccine, 2017, 10.1016/j.vaccine.2017.05.049
Inhibition of human metapneumovirus replication by small interfering RNA., Boivin G, Johnson PH, Quay SC, Templin MV, Seth S, Ge Q, Cui K, Goyette N, Cavanagh MH, Deffrasnes C, Antiviral therapy, 2008
Peramivir susceptibilities of recombinant influenza A and B variants selected with various neuraminidase inhibitors, Boivin, G., Abed, Y., Carbonneau, J., Tu, V., Fage, C., Antiviral Therapy, 2017, 10.3851/IMP3158
The importance of frailty in the assessment of influenza vaccine effectiveness against influenza-related hospitalization in elderly people, McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Stiver, G., Semret, M., Richardson, D., Powis, J., Mcgeer, A., McCarthy, A., Mackinnon-Cameron, D., Loeb, M., Leblanc, J., Langley, J., Katz, K., Johnstone, J., Ibarguchi, B., Halperin, S., Green, K., Elsherif, M., Chit, A., Bowie, W., Boivin, G., Ambrose, A., Mcelhaney, B.J.E., Santos, G.D., Haguinet, F., Hatchette, T., Ye, L., Shinde, V., Andrew, M.K., Journal of Infectious Diseases, 2017, 10.1093/infdis/jix282
Characterization of contemporary influenza B recombinant viruses harboring mutations of reduced susceptibility to baloxavir marboxil, in vitro and in mice, Boivin, G., Venable, M.-C., Checkmahomed, L., Fage, C., Abed, Y., Antiviral Research, 2020, 10.1016/j.antiviral.2020.104807
Whole-genome characterization and genotyping of global WU polyomavirus strains., Sloots TP, Lindau C, Leach AJ, Gilroy NM, Ferguson PE, Chung JY, Cheng AC, Boivin G, Binks M, Allander T, Abed Y, Whiley DW, Rockett R, Bialasiewicz S, Journal of virology, 2010, 10.1128/jvi.02658-09
Antibody persistence and response to 2010-2011 trivalent influenza vaccine one year after a single dose of 2009 AS03-adjuvanted pandemic H1N1 vaccine in children, Skowronski, D., Gilca, R., Dionne, M., Sauvageau, C., Boulianne, N., Ouakki, M., Boivin, G., Hamelin, M.-E., De Serres, G., Gilca, V., Vaccine, 2011, 10.1016/j.vaccine.2011.10.062
The impact of trained immunity in respiratory viral infections, Guy Boivin, Jocelyne Piret, Reviews in Medical Virology, 2024, 10.1002/rmv.2510
Infiltration pattern of blood monocytes into the central nervous system during experimental herpes simplex virus encephalitis, Boivin, G., Piret, J., Canivet, C., Menasria, R., PLoS ONE, 2015, 10.1371/journal.pone.0145773
Evaluation of the AMPLICOR cytomegalovirus test with specimens from human immunodeficiency virus-infected subjects., Bergeron MG, Sun R, Tevere VJ, Lalonde R, Murray G, Toma E, Handfield J, Boivin G, Journal of clinical microbiology, 1998, 10.1128/jcm.36.9.2509-2513.1998
Sequence analysis of the N, P, M and F genes of Canadian human metapneumovirus strains., Li Y, Anderson LJ, Boivin G, Peret TC, Ward D, Taylor T, Normand S, Bastien N, Virus research, 2003, 10.1016/s0168-1702(03)00065-0
Development of a universal influenza A vaccine based on the M2e peptide fused to the papaya mosaic virus (PapMV) vaccine platform., Leclerc D, Boivin G, Lopez Macias C, Lopez Macias C, Pare C, Savard C, Abed Y, Baz M, Koukavica I, Hamelin ME, Zhao Y, Acosta-Ramirez E, Denis J, Vaccine, 2008, 10.1016/j.vaccine.2008.04.052
Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations., Boivin G, Goyette N, Abed Y, Antimicrobial agents and chemotherapy, 2005, 10.1128/aac.49.2.556-559.2005
Genetic diversity between human metapneumovirus subgroups., Buchholz UJ, Collins PL, Murphy BR, Hanson CT, Boivin G, Skiadopoulos MH, Biacchesi S, Virology, 2003, 10.1016/s0042-6822(03)00528-2
Tumor necrosis factor-alpha and interleukin-1 beta play a critical role in the resistance against lethal herpes simplex virus encephalitis., Boivin G, Rivest S, Sergerie Y, The Journal of infectious diseases, 2007, 10.1086/520094
Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir., Boivin G, Abed Y, Baz M, Antiviral research, 2006, 10.1016/j.antiviral.2006.10.012
A trial of valganciclovir prophylaxis for cytomegalovirus prevention in lung transplant recipients., Lien D, Nia S, Jackson K, Fenton J, Siegal D, Boivin G, Preiksaitis J, Kumar D, Humar A, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2005, 10.1111/j.1600-6143.2005.00866.x
Generation and Characterization of Drug-Resistant Influenza B Viruses Selected In Vitro with Baloxavir Acid, Guy Boivin, Julie Carbonneau, Yacine Abed, Amel Saim-Mamoun, Pathogens, 2022, 10.3390/pathogens11091048
Quantitative analysis of cytomegalovirus (CMV) viremia using the pp65 antigenemia assay and the COBAS AMPLICOR CMV MONITOR PCR test after blood and marrow allogeneic transplantation., Roy J, Goyette N, Demers C, Béliveau C, Delage R, Bélanger R, Boivin G, Journal of clinical microbiology, 2000, 10.1128/jcm.38.12.4356-4360.2000
Activity of the neuraminidase inhibitor A-315675 against oseltamivir-resistant influenza neuraminidases of N1 and N2 subtypes., Boivin G, Baz M, Nehmé B, Abed Y, Antiviral research, 2007, 10.1016/j.antiviral.2007.08.008
Evaluation of Epstein-Barr virus, human herpesvirus 6 (HHV-6), and HHV-8 antiviral drug susceptibilities by use of real-time-PCR-based assays., Boivin G, Goyette N, Piret J, Bounaadja L, Journal of clinical microbiology, 2013, 10.1128/jcm.03234-12
In vitro and in vivo evidence of a potential A(H1N1)pdm09 antigenic drift mediated by escape mutations in the haemagglutinin Sa antigenic site, Boivin, G., Baz, M., Rhéaume, C., Abed, Y., Retama, M., Journal of General Virology, 2017, 10.1099/jgv.0.000800
Human bocavirus infections in hospitalized children and adults., Boivin G, Bergeron MG, Leblanc E, de Serres G, Gilca R, Bastien M, Longtin J, Emerging infectious diseases, 2008, 10.3201/eid1402.070851
Innate immune response during herpes simplex virus encephalitis and development of immunomodulatory strategies, Boivin, G., Piret, J., Reviews in Medical Virology, 2015, 10.1002/rmv.1848
Herpesvirus DNA polymerases: Structures, functions and inhibitors, Boivin, G., Piret, J., Zarrouk, K., Virus Research, 2017, 10.1016/j.virusres.2017.01.019
Evaluation of a rapid optical immunoassay for influenza viruses (FLU OIA test) in comparison with cell culture and reverse transcription-PCR., Kress A, Hardy I, Boivin G, Journal of clinical microbiology, 2001, 10.1128/jcm.39.2.730-732.2001
Molecular and antigenic evolution of human influenza A/H3N2 viruses in Quebec, Canada, 2009-2011, Boivin, G., Hamelin, M.-T., Rhéaume, C., Bouhy, X., Papenburg, J., Ann, J., Journal of Clinical Virology, 2012, 10.1016/j.jcv.2011.09.016
Distribution and clinical impact of human respiratory syncytial virus genotypes in hospitalized children over 2 winter seasons., Boivin G, Dery P, Bergeron MG, Leblanc E, Vachon ML, Tremblay M, De Serres G, Gilca R, The Journal of infectious diseases, 2005, 10.1086/498526
Cross-lineage influenza B and heterologous influenza A antibody responses in vaccinated mice: immunologic interactions and B/Yamagata dominance., Boivin G, Bouhy X, Rhéaume C, Gardy JL, De Serres G, Hamelin ME, Janjua NZ, Skowronski DM, PloS one, 2012, 10.1371/journal.pone.0038929
Phenotypic and genotypic characterization of acyclovir-resistant herpes simplex viruses from immunocompromised patients., Boivin G, Erice A, Balfour HH, Hill E, Gaudreau A, The Journal of infectious diseases, 1998, 10.1086/515626
Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy., Boivin G, Bestman-Smith J, Journal of medical virology, 2002, 10.1002/jmv.2195
Effect of ribavirin and glucocorticoid treatment in a mouse model of human metapneumovirus infection., Boivin G, Prince GA, Hamelin ME, Antimicrobial agents and chemotherapy, 2006, 10.1128/aac.50.2.774-777.2006
Synergistic PA and HA mutations confer mouse adaptation of a contemporary A/H3N2 influenza virus, Boivin, G., Abed, Y., Couture, C., Lavigne, S., Carbonneau, J., M’hamdi, Z., Baz, M., Scientific Reports, 2019, 10.1038/s41598-019-51877-4
Novel antiviral compounds and combination therapy for influenza viruses,Nouveaux composés antiviraux et thérapie combinée contre les virus influenza, Lina, B., Rosa-Calatrava, M., Boivin, G., Virologie, 2019, 10.1684/vir.2019.0803
The combination of oseltamivir with azithromycin does not show additional benefits over oseltamivir monotherapy in mice infected with influenza A(H1N1)pdm2009 virus, Boivin, G., Abed, Y., Rhéaume, C., Pizzorno, A., Fage, C., Journal of Medical Virology, 2017, 10.1002/jmv.24911
Thymidine kinase mutations conferring acyclovir resistance in herpes simplex type 1 recombinant viruses., Boivin G, Sergerie Y, Antimicrobial agents and chemotherapy, 2006, 10.1128/aac.00889-06
Impact of neuraminidase mutations conferring influenza resistance to neuraminidase inhibitors in the N1 and N2 genetic backgrounds., Boivin G, Baz M, Abed Y, Antiviral therapy, 2006
Predominant role of IPS-1 over TRIF adaptor proteins in early innate immune response against Zika virus in mice, Boivin, G., Baz, M., Rhéaume, C., Carbonneau, J., Piret, J., Journal of General Virology, 2018, 10.1099/jgv.0.000992
Antiviral Drug Resistance in Herpesviruses, Guy Boivin, Emilien Drouot, Jocelyne Piret, Handbook of Antimicrobial Resistance, 2014, 10.1007/978-1-4939-0667-3_7-1
Phenotypic evaluation of previously uncharacterized cytomegalovirus DNA polymerase sequence variants detected in a valganciclovir treatment trial, Elston, R., Ives, J., Boivin, G., Chou, S., Journal of Infectious Diseases, 2014, 10.1093/infdis/jit654
Resistance of herpesviruses to antiviral drugs: clinical impacts and molecular mechanisms., Boivin G, Bestman-Smith J, Gilbert C, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 2002, 10.1016/s1368-7646(02)00021-3
Analysis of replication kinetics of the human metapneumovirus in different cell lines by real-time PCR., Boivin G, Côté S, Deffrasnes C, Journal of clinical microbiology, 2005, 10.1128/jcm.43.1.488-490.2005
Role of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug foscarnet., Götte M, Boivin G, Gilbert C, Tchesnokov EP, Journal of virology, 2006, 10.1128/jvi.80.3.1440-1450.2006
Human parechovirus causes encephalitis with white matter injury in neonates., de Vries LS, Boivin G, van Loon AM, Hellmann J, Hahn CD, Groenendaal F, Verboon-Maciolek MA, Annals of neurology, 2008, 10.1002/ana.21445
Evolution of oseltamivir resistance mutations in influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice, Boivin, G., Corbeil, J., Hamelin, M.-È., Carbonneau, J., Baz, M., Plante, P.-L., Abed, Y., Pizzorno, A., Antimicrobial Agents and Chemotherapy, 2014, 10.1128/AAC.02956-14
Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period., Boivin G, Li Y, Coulthart MB, Abed Y, Virus genes, 2003, 10.1023/a:1025768308631
Characterization of multiple cytomegalovirus drug resistance mutations detected in a hematopoietic stem cell transplant recipient by recombinant phenotyping, Boivin, G., Lebel, M.H., Piret, J., Drouot, E., Journal of Clinical Microbiology, 2014, 10.1128/JCM.02205-14
Zika-Induced Male Infertility in Mice Is Potentially Reversible and Preventable by Deoxyribonucleic Acid Immunization, Boivin, G., Kobinger, G.P., Weiner, D.B., Muthumani, K., Kim, J.J., Sardesai, N.Y., Maslow, J.N., Roberts, C.C., Park, Y.K., Magalhães, K.G., Tremblay, R.R., Das Neves Almeida, R., Couture, C., Carbonneau, J., Venable, M.-C., Rhéaume, C., Griffin, B.D., Piret, J., De La Vega, M.-A., Journal of Infectious Diseases, 2019, 10.1093/infdis/jiy336
Early effects of ganciclovir therapy on the quantity of cytomegalovirus DNA in leukocytes of immunocompromised patients., Jordan MC, Germain M, Kringstad BA, Quirk MR, Boivin G, Antimicrobial agents and chemotherapy, 1997, 10.1128/aac.41.4.860
Analysis of HHV-6 mutations in solid organ transplant recipients at the onset of cytomegalovirus disease and following treatment with intravenous ganciclovir or oral valganciclovir., Boivin G, Goyette N, Piret J, Bounaadja L, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2013, 10.1016/j.jcv.2013.06.024
Comparison of Automated Microarray Detection with Real-Time PCR Assays for Detection of Respiratory Viruses in Specimens Obtained from Children, Corbeil J, Boivin G, De Serres G, Wu W, Boisvert S, Robitaille L, Boucher N, Carbonneau J, Raymond F, Journal of clinical microbiology, 2010
Sequence polymorphism of the predicted human metapneumovirus G glycoprotein., Boivin G, Erdman DD, Anderson LJ, Abed Y, Peret TCT, The Journal of general virology, 2004, 10.1099/vir.0.19504-0
Repurposing of drugs as novel influenza inhibitors from clinical gene expression infection signatures, Rosa-Calatrava, M., Boivin, G., Textoris, J., Legras-Lachuer, C., Lina, B., Poissy, J., Escuret, V., Croze, S., Rhéaume, C., Hamelin, M.-E., Roche, M., Traversier, A., Padey, B., Julien, T., de Lamballerie, C.N., Terrier, O., Pizzorno, A., Frontiers in Immunology, 2019, 10.3389/fimmu.2019.00060
A collaborative study to establish the 1st WHO International Standard for human cytomegalovirus for nucleic acid amplification technology., Collaborative Study Group, Minor PD, Heath AB, Fryer JF, Biologicals : journal of the International Association of Biological Standardization, 2016, 10.1016/j.biologicals.2016.04.005
Duration of isolation and contagiousness in coronavirus disease 2019 (COVID-19) patients receiving tocilizumab and dexamethasone: A case series, Marie-Claude Roy, Marie-Ève Hamelin, Julie Carbonneau, Julie Bestman-Smith, Annie Ruest, Vilayvong Loungnarath, Guy Boivin, Florence Côté, Infection Control & Hospital Epidemiology, 2023, 10.1017/ice.2022.14
Human metapneumovirus-associated lower respiratory tract infections among hospitalized human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants., Boivin G, Klugman KP, Abed Y, Ludewick H, Madhi SA, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, 10.1086/379771
The changing landscape of respiratory viruses contributing to respiratory hospitalisations: results from a hospital-based surveillance in Quebec, Canada, 2012-13 to 2021-22, Jeannot Dumaresq, Hugues Charest, Guy Boivin, Charles Frenette, Sara Carazo, Rachid Amini, Rodica Gilca, 2022, 10.1101/2022.07.01.22277061
Molecular characterization of viruses from clinical respiratory samples producing unidentified cytopathic effects in cell culture., Boivin G, Abed Y, Viruses, 2009, 10.3390/v1020084
Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton rats., Boivin G, Prince GA, Blanco JC, Boukhvalova M, Cragin RP, Kuhn KH, Yim K, Hamelin ME, Journal of virology, 2005, 10.1128/jvi.79.14.8894-8903.2005
Seroconversion to seasonal influenza viruses after A(H1N1)pdm09 virus infection, Quebec, Canada., Boivin G, De Serres G, Skowronski DM, Ouakki M, Papenburg J, Hamelin ME, Baz M, Emerging infectious diseases, 2012, 10.3201/eid1807.111680
A nasally administered trivalent inactivated influenza vaccine is well tolerated, stimulates both mucosal and systemic immunity, and potentially protects against influenza illness., Fries L, Boivin G, Alexander M, Papp K, Dzongowski P, Lasko B, White L, Shu D, Gorfinkel I, Stiver G, Angel JB, McGeer A, Ward BJ, Aoki F, Langley JM, Vaccine, 2011, 10.1016/j.vaccine.2010.12.100
Herpesvirus Resistance to Antiviral Drugs, Guy Boivin, Jocelyne Piret, Antimicrobial Drug Resistance, 2017, 10.1007/978-3-319-47266-9_24
Infectivity of healthcare workers diagnosed with SARS-CoV-2 infection approximately 2 weeks after onset of symptoms: A cross-sectional study, de Serres, G., Roger, M., Villeneuve, J., Farfard, J., Boivin, G., Baz, M., Savard, P., Quach, C., Charest, H., Longtin, Y., Infection Control and Hospital Epidemiology, 2020, 10.1017/ice.2020.1420
Neuraminidase-inhibitor resistance testing for pandemic influenza A (H1N1) 2009 in Ontario, Canada., Gubbay J, Boivin G, Low D, Li Y, Bastien N, Lee C, Sarabia A, Tran D, Doyle J, Olsha R, Alexander D, Higgins R, Lombos E, Eshaghi A, Patel S, Longtin J, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2011, 10.1016/j.jcv.2010.12.007
Molecular characterization of a Canadian human parechovirus (HPeV)-3 isolate and its relationship to other HPeVs., Boivin G, Abed Y, Journal of medical virology, 2005, 10.1002/jmv.20493
DNA polymerases of herpesviruses and their inhibitors, Guy Boivin, Jocelyne Piret, Viral Replication Enzymes and their Inhibitors Part B, 2021, 10.1016/bs.enz.2021.07.003
Cytomegalovirus seropositivity is associated with increased microbial translocation in people living with human immunodeficiency virus and uninfected controls, Routy, J.-P., Boivin, G., Ancuta, P., Tremblay, C., Durand, M., Chartrand-Lefebvre, C., Lebouché, B., Costiniuk, C., Finkelman, M., Zhang, Y., Mehraj, V., Ouyang, J., Fombuena, B., Lin, J., Isnard, S., Ramendra, R., Clinical Infectious Diseases, 2020, 10.1093/cid/ciz1001
A novel neuraminidase deletion mutation conferring resistance to oseltamivir in clinical influenza A/H3N2 virus., Boivin G, Baz M, Abed Y, The Journal of infectious diseases, 2009, 10.1086/595736
Antiviral drug resistance in herpesviruses other than cytomegalovirus, Boivin, G., Piret, J., Reviews in Medical Virology, 2014, 10.1002/rmv.1787
In vitro activity of letermovir against human cytomegalovirus isolates with different drug susceptibility phenotypes, Guy Boivin, Nathalie Goyette, Jocelyne Piret, Antiviral Research, 2022, 10.1016/j.antiviral.2022.105328
Quantitation of cytomegalovirus DNA and characterization of viral gene expression in bronchoalveolar cells of infected patients with and without pneumonitis., Jordan MC, Hertz MI, Kringstad B, Quirk MR, Olson CA, Boivin G, The Journal of infectious diseases, 1996, 10.1093/infdis/173.6.1304
Antiviral resistance in herpes simplex virus and varicella-zoster virus infections: Diagnosis and management, Boivin, G., Piret, J., Current Opinion in Infectious Diseases, 2016, 10.1097/QCO.0000000000000288
Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups., Anderson LJ, Erdman DD, Peret TC, Côté S, Moisan D, Ruel L, Pelletier G, Abed Y, Boivin G, The Journal of infectious diseases, 2002, 10.1086/344319
Neurovirulence and latency of drug-resistant clinical herpes simplex viruses in animal models., Boivin G, Sergerie Y, Canas J, Miles B, Yim K, Martin M, Dambrosi S, Journal of medical virology, 2010, 10.1002/jmv.21773
Comparison of automated microarray detection with real-time PCR assays for detection of respiratory viruses in specimens obtained from children., Corbeil J, Boivin G, De Serres G, Wu WK, Boisvert S, Robitaille L, Boucher N, Carbonneau J, Raymond F, Journal of clinical microbiology, 2009, 10.1128/jcm.01297-08
Incidence and characterization of cytomegalovirus resistance mutations among pediatric solid organ transplant patients who received valganciclovir prophylaxis., Boivin G, Ives J, Goyette N, Martin M, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2010, 10.1016/j.jcv.2010.01.009
Characterization of human metapneumoviruses isolated from patients in North America., Anderson LJ, Erdman DD, Osterhaus AD, Humphrey C, Couillard M, Li Y, Boivin G, Peret TC, The Journal of infectious diseases, 2002, 10.1086/340518
Design considerations in building in silico equivalents of common experimental influenza virus assays., Beauchemin CA, Boivin G, Simon P, Liao LE, Holder BP, Autoimmunity, 2011, 10.3109/08916934.2011.523267
Cytomegalovirus quantification in plasma with Abbott RealTime CMV and Roche Cobas Amplicor CMV assays, Longtin, J., Boivin, G., Deschênes, L., Rodrigue, M.-A., Tremblay, M.-A., Journal of Virological Methods, 2015, 10.1016/j.jviromet.2015.08.010
New reporter cell line to evaluate the sequential emergence of multiple human cytomegalovirus mutations during in vitro drug exposure., Boivin G, Gilbert C, Antimicrobial agents and chemotherapy, 2005, 10.1128/aac.49.12.4860-4866.2005
Characterization of drug-resistant influenza virus A(H1N1) and A(H3N2) variants selected in vitro with laninamivir, Boivin, G., Pryor, M.J., Tucker, S.P., Luttick, A., Hamilton, S., Desrochers, F.-M., Abed, Y., Samson, M., Antimicrobial Agents and Chemotherapy, 2014, 10.1128/AAC.03313-14
Human herpesvirus 8 infection of the genital tract of HIV-seropositive and HIV-seronegative women at risk of sexually transmitted diseases. Canadian Women's HIV Study Group., Coutlée F, Forest P, Gaudreau A, Walmsley S, Lapointe N, Hankins C, Boivin G, AIDS (London, England), 2000, 10.1097/00002030-200005260-00028
Both TRIF and IPS-1 adaptor proteins contribute to the cerebral innate immune response against herpes simplex virus 1 infection., Boivin G, Gosselin J, Piret J, Lebel M, Boivin N, Menasria R, Journal of virology, 2013, 10.1128/jvi.00591-13
Reply to "Calibration technologies for correct determination of Epstein-Barr Virus, human herpesvirus 6 (HHV-6), and HHV-8 antiviral drug susceptibilities by use of real-time-PCR-based assays"., Boivin G, Goyette N, Piret J, Bounaadja L, Journal of clinical microbiology, 2013, 10.1128/jcm.00545-13
Recent developments with live-attenuated recombinant paramyxovirus vaccines., Boivin G, Rosa-Calatrava M, Lina B, Le Bayon JC, Reviews in medical virology, 2012, 10.1002/rmv.1717
Treatment with a novel topical nanoemulsion (NB-001) speeds time to healing of recurrent cold sores, Baker, J.R., Stanberry, L.R., Boivin, G., Sutcliffe, J., Ijzerman, M., Ciotti, S., Flack, M.R., Jarratt, M., Jones, T.M., Kircik, L., Journal of Drugs in Dermatology, 2012
Evaluation of susceptibility of human herpesvirus 8 to antiviral drugs by quantitative real-time PCR., Boivin G, Sergerie Y, Journal of clinical microbiology, 2003, 10.1128/jcm.41.8.3897-3900.2003
Influenza A(H1N1)pdm09 Virus but Not Respiratory Syncytial Virus Interferes with SARS-CoV-2 Replication during Sequential Infections in Human Nasal Epithelial Cells, Guy Boivin, Jocelyne Piret, Julie Carbonneau, Mathilde Hénaut, Clément Fage, Viruses, 2022, 10.3390/v14020395
In vitro properties and virulence of contemporary recombinant influenza b viruses harboring mutations of cross-resistance to neuraminidase inhibitors, Boivin, G., Venable, M.-C., Checkmahomed, L., Abed, Y., Fage, C., Viruses, 2019, 10.3390/v11010006
Characterization of multidrug-resistant influenza A/H3N2 viruses shed during 1 year by an immunocompromised child., Boivin G, McDonald J, Abed Y, Baz M, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, 10.1086/508777
Norwalk-like gastroenteritis epidemic in a teaching hospital--Quebec., Courtinat Y, Murray G, Boivin G, Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada, 1990
Pandemics Throughout History, Boivin, G., Piret, J., Frontiers in Microbiology, 2021, 10.3389/fmicb.2020.631736
Expression of the late cytomegalovirus (CMV) pp150 transcript in leukocytes of AIDS patients is associated with a high viral DNA load in leukocytes and presence of CMV DNA in plasma., Bergeron MG, Lalonde R, Toma E, Handfield J, Boivin G, The Journal of infectious diseases, 1999, 10.1086/314721
In Vitro Selection of Remdesivir-Resistant SARS-CoV-2 Demonstrates High Barrier to Resistance, Guy Boivin, Danielle P. Porter, Jiani Li, Jason K. Perry, Nicholas C. Riola, Venice Du Pont, Liva Checkmahomed, 2022, 10.1101/2022.02.07.479493
Novel calixarene-based surfactant enables low dose split inactivated vaccine protection against influenza infection, Jawhari, A., Rosa-Calatrava, M., Dejean, E., Boivin, G., Lina, B., Hamelin, M.E., Champagne, A., Traversier, A., Pizzorno, A., Mandon, E.D., Vaccine, 2020, 10.1016/j.vaccine.2019.10.018
Influenza virus susceptibility and resistance to oseltamivir., Roberts N, Boivin G, Aoki FY, Antiviral therapy, 2007
A review of influenza vaccine immunogenicity and efficacy in HIV-infected adults., Halperin S, Boivin G, Klein MB, Mills E, Fergusson D, Hutton B, Cooper C, The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2008, 10.1155/2008/419710
Human metapneumovirus: enhanced pulmonary disease in cotton rats immunized with formalin-inactivated virus vaccine and challenged., Prince GA, Porter DD, Boivin G, Hamlin ME, Blanco JC, Boukhvalova MS, Cragin RP, Yim KC, Vaccine, 2007, 10.1016/j.vaccine.2007.04.075
Novel method based on real-time cell analysis for drug susceptibility testing of herpes simplex virus and human cytomegalovirus, Boivin, G., Goyette, N., Piret, J., Journal of Clinical Microbiology, 2016, 10.1128/JCM.03274-15
Epitope mapping of the 2009 pandemic and the A/brisbane/59/2007 seasonal (H1N1) influenza virus haemagglutinins using mabs and escape mutants, Boivin, G., Corbeil, J., Abed, Y., Retamal, M., Journal of General Virology, 2014, 10.1099/vir.0.067819-0
Influenza virus resistance to neuraminidase inhibitors., Boivin G, Abed Y, Pizzorno A, Samson M, Antiviral research, 2013, 10.1016/j.antiviral.2013.03.014
Immunogenicity and tolerability of an inactivated and adjuvanted pandemic H1N1 influenza vaccine, in HIV-1-infected patients., Boivin G, Sékaly RP, Trautman L, Sampalis J, Baz M, Cote S, Cyr L, Sylla M, Toma E, Fortin C, Rouleau D, Tremblay CL, Vaccine, 2010, 10.1016/j.vaccine.2010.12.023
Management of Cytomegalovirus Infections in the Era of the Novel Antiviral Players, Letermovir and Maribavir, Guy Boivin, Jocelyne Piret, Infectious Disease Reports, 2024, 10.3390/idr16010005
The E119D neuraminidase mutation identified in a multidrug-resistant influenza A(H1N1)pdm09 isolate severely alters viral fitness in vitro and in animal models, Boivin, G., Kaiser, L., Mallett, C., Beaulieu, E., Joly, M.-H., Dubé, K., Fage, C., Retamal, M., Pizzorno, A., Rhéaume, C., L'Huillier, A.G., Bouhy, X., Abed, Y., Antiviral Research, 2016, 10.1016/j.antiviral.2016.05.006
Intrahost dynamics of antiviral resistance in influenza a virus reflect complex patterns of segment linkage, reassortment, and natural selection, Ghedina, E., Boivin, G., Holmes, E.C., Cui, L., Twaddle, A., Fitch, A., Hamelin, M.-E., Greenbaum, B.D., Sebra, R., Song, T., Rogers, M.B., mBio, 2015, 10.1128/mBio.02464-14
Ganciclovir susceptibilities of cytomegalovirus (CMV) isolates from solid organ transplant recipients with CMV viremia after antiviral prophylaxis., Balfour HH, Dunn DL, Crane DD, Erice A, Boivin G, The Journal of infectious diseases, 1993, 10.1093/infdis/168.2.332
Efficacy of Colchicine in Non-Hospitalized Patients with COVID-19, for the COLCORONA Investigators, Denault A, Dupuis J, Audet S, Verret L, da Luz P, Lopez-Sendon J, Shah B, Pillinger MH, Gaudet D, L’Allier PL, Bouabdallaoui N, Tardif J, 2021, 10.1101/2021.01.26.21250494
Emergence of an oseltamivir-resistant influenza A/H3N2 Virus in an elderly patient receiving a suboptimal dose of antiviral prophylaxis, Boivin, G., Bouhy, X., Abed, Y., Roussy, J.-F., Journal of Clinical Microbiology, 2013, 10.1128/JCM.02659-13
Randomized controlled ferret study to assess the direct impact of 2008-09 trivalent inactivated influenza vaccine on A(H1N1)pdm09 disease risk, Boivin, G., Koopmans, M., Petric, M., Lavigne, S., Balshaw, R., De Bruin, E., Embury-Hyatt, C., Kobasa, D., Couture, C., Leung, A., Bouhy, X., Sabaiduc, S., Li, G., Janjua, N.Z., De Serres, G., Hamelin, M.-E., Skowronski, D.M., PLoS ONE, 2014, 10.1371/journal.pone.0086555
Molecular pathway of influenza pan-neuraminidase inhibitor resistance in an immunocompromised patient, Boivin, G., Kaiser, L., Goncalves, A.R., Giannotti, F., Fage, C., Venable, M.-C., Carbonneau, J., Checkmahomed, L., Schibler, M., Abed, Y., Antiviral Therapy, 2020, 10.3851/imp3344
Virus-like particle vaccine induces cross-protection against human metapneumovirus infections in mice., Cosset FL, Boivin G, Lavillette D, Szécsi J, Granier C, Hamelin MÈ, Aerts L, Lévy C, Vaccine, 2013, 10.1016/j.vaccine.2013.03.051
Comparison of pandemic and seasonal influenza in the pediatric emergency department., Boivin G, De Serres G, Guimont C, Fontela PS, Ouakki M, Papenburg J, Aguirre E, The Pediatric infectious disease journal, 2011, 10.1097/inf.0b013e3182103d54
Global genetic diversity of human metapneumovirus fusion gene., LeBlanc E, Gray GC, Ludewick H, Shemer-Avni Y, Wolf D, Freymuth F, Madhi S, Sloots TP, Mackay I, Boivin G, Emerging infectious diseases, 2004, 10.3201/eid1006.031097
Systematic review of influenza resistance to the neuraminidase inhibitors., Thabane L, Boivin G, Awad T, Thorlund K, BMC infectious diseases, 2011, 10.1186/1471-2334-11-134
The prophylactic administration of a monoclonal antibody against human metapneumovirus attenuates viral disease and airways hyperresponsiveness in mice., Boivin G, Ulbrandt N, Suzich J, Kiener P, Sackett M, Couture C, Hamelin ME, Antiviral therapy, 2008
Droplet digital PCR to investigate quasi-species at codons 119 and 275 of the A(H1N1)pdm09 neuraminidase during zanamivir and oseltamivir therapies, Boivin, G., Kaiser, L., L'Huillier, A.G., Carbonneau, J., Abed, Y., Journal of Medical Virology, 2017, 10.1002/jmv.24680
Respiratory tract reinfections by the new human Metapneumovirus in an immunocompromised child., Boivin G, Abed Y, Déry P, Pelletier G, Emerging infectious diseases, 2002, 10.3201/eid0809.020238
Rate of emergence of cytomegalovirus (CMV) mutations in leukocytes of patients with acquired immunodeficiency syndrome who are receiving valganciclovir as induction and maintenance therapy for CMV retinitis., Roberts NA, Sudlow R, Greenfield I, Gaudreau A, Gilbert C, Boivin G, The Journal of infectious diseases, 2001, 10.1086/324672
Mapping and characterization of the primary and anamnestic H-2(d)-restricted cytotoxic T-lymphocyte response in mice against human metapneumovirus., Polack FP, Kleeberger SR, Collins PL, Boivin G, Buchholz UJ, Zavala F, Melendi GA, Journal of virology, 2007, 10.1128/jvi.02423-06
Adjuvant effect of the human metapneumovirus (HMPV) matrix protein in HMPV subunit vaccines, Boivin, G., Hamelin, M.-É.V., Couture, C., Lavigne, S., Carbonneau, J., Aume, C.R., Aerts, L., Journal of General Virology, 2015, 10.1099/vir.0.000031
The 2009 pandemic H1N1 D222G hemagglutinin mutation alters receptor specificity and increases virulence in mice but not in ferrets, Boivin, G., Kobasa, D., Couture, C., Joubert, P., Leung, A., Hamelin, M.-E., Pizzorno, A., Abed, Y., Journal of Infectious Diseases, 2011, 10.1093/infdis/jir483
Infections by human coronavirus-NL in hospitalized children., De Serres G, Déry P, Bergeron MG, Leblanc E, Deffrasnes C, Gilca R, Côté S, Baz M, Boivin G, The Pediatric infectious disease journal, 2005, 10.1097/01.inf.0000183743.68569.c7
Influenza vaccine effectiveness against influenza-related hospitalization during a season with mixed outbreaks of four influenza viruses: A test-negative case-control study in adults in Canada, McNeil, S.A., Ye, L., Webster, D., Valiquette, L., Trottier, S., Stiver, G., Semret, M., Richardson, D., Powis, J., Nichols, M.K., McGeer, A., McElhaney, J., McCarthy, A., MacKinnon-Cameron, D., Loeb, M., LeBlanc, J., Langley, J.M., Katz, K., Johnstone, J., Ibarguchi, B., Halperin, S.A., Haguinet, F., Green, K., ElSherif, M., Dos Santos, G., Chit, A., Bowie, W., Boivin, G., Ambrose, A., Hatchette, T., Shinde, V., Andrew, M.K., BMC Infectious Diseases, 2017, 10.1186/s12879-017-2905-8
Evaluation of anticoagulant agents for the treatment of human metapneumovirus infection in mice, Boivin, G., Hamelin, M.-È., Venable, M.-C., Checkmahomed, L., Couture, C., Jandrot-Perrus, M., Lê, B.V., Journal of General Virology, 2018, 10.1099/jgv.0.001135
Effect of in vitro syncytium formation on the severity of human metapneumovirus disease in a murine model, Boivin, G., Hamelin, M.-È., Couture, C., Lavigne, S., Rhéaume, C., Carbonneau, J., Dubois, J., Cavanagh, M.-H., Aerts, L., PLoS ONE, 2015, 10.1371/journal.pone.0120283
Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet., Boivin G, Lin SX, Goyette N, Azzi A, Gilbert C, Antimicrobial agents and chemotherapy, 2011, 10.1128/aac.00334-11
Evaluation of the human herpesvirus 8 DNA load in blood and Kaposi's sarcoma skin lesions from AIDS patients on highly active antiretroviral therapy., Routy JP, Gaudreau A, Boivin G, AIDS (London, England), 2000, 10.1097/00002030-200009080-00004
Valacyclovir combined with artesunate or rapamycin improves the outcome of herpes simplex virus encephalitis in mice compared to antiviral therapy alone, Boivin, G., Piret, J., Rhéaume, C., Menasria, R., Canivet, C., Antiviral Research, 2015, 10.1016/j.antiviral.2015.09.007
Targeted Proteomics of Human Metapneumovirus in Clinical Samples and Viral Cultures, Moseley, M.A., Corbeil, J., Boivin, G., Plante, P.-L., Robitaille, L., Gerhardt, G., Foster, M.W., Analytical Chemistry, 2015, 10.1021/acs.analchem.5b01544
Cross-reactive antibody to swine influenza A(H3N2) subtype virus in children and adults before and after immunisation with 2010/11 trivalent inactivated influenza vaccine in Canada, August to November 2010., Boivin G, Rhéaume C, Hamelin ME, Dionne M, Gilca V, Gardy JL, Janjua NZ, De Serres G, Skowronski DM, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2012, 10.2807/ese.17.04.20066-en
Recombinant phenotyping of cytomegalovirus sequence variants detected after 200 or 100 days of valganciclovir prophylaxis., Elston R, Ives JA, Farhan M, Goyette N, Boivin G, Marousek G, Chou S, Transplantation, 2010, 10.1097/tp.0b013e3181fdd9d2
Predicting influenza infections during epidemics with use of a clinical case definition., Maziade J, Tellier G, Hardy I, Boivin G, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, 10.1086/317425
Enhanced lung disease and Th2 response following human metapneumovirus infection in mice immunized with the inactivated virus., Boivin G, Sackett MK, Couture C, Hamelin MÈ, The Journal of general virology, 2007, 10.1099/vir.0.83250-0
Human parechovirus types 1, 2 and 3 infections in Canada., Boivin G, Abed Y, Emerging infectious diseases, 2006, 10.3201/eid1206.051675
Viral Fitness of Baloxavir-Resistant Recombinant Influenza B/Victoria- and B/Yamagata-like Viruses Harboring the I38T PA Change, In Vitro, Ex Vivo and in Guinea Pigs, Guy Boivin, Yacine Abed, Chantal Rhéaume, Julie Carbonneau, Amel Saim-Mamoun, Microorganisms, 2023, 10.3390/microorganisms11051095
Generation and characterization of recombinant pandemic influenza A(H1N1) viruses resistant to neuraminidase inhibitors., Boivin G, Abed Y, Bouhy X, Pizzorno A, The Journal of infectious diseases, 2011, 10.1093/infdis/jiq010
An Early Microglial Response Is Needed to Efficiently Control Herpes Simplex Virus Encephalitis, Boivin, G., Rivest, S., Zarrouk, K., Carbonneau, J., Venable, M.-C., Piret, J., Laflamme, N., Uyar, O., Journal of Virology, 2020, 10.1128/JVI.01428-20
Cytomegalovirus (CMV) glycoprotein B genotypes and response to antiviral therapy, in solid-organ-transplant recipients with CMV disease., Boivin G, Gilbert C, Kumar D, Humar A, The Journal of infectious diseases, 2003, 10.1086/377002
Pathogenicity and response to topical antiviral therapy in a murine model of acyclovir-sensitive and acyclovir-resistant herpes simplex viruses isolated from the same patient., Boivin G, Lebel A, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2006, 10.1016/j.jcv.2006.05.003
Comparison of early and recent influenza A(H1N1)pdm09 isolates harboring or not the H275Y neuraminidase mutation, in vitro and in animal models, Boivin, G., Kobinger, G., Dufresne, S.F., Marie-Ève-Hamelin, Fage, C., Venable, M.-C., Checkmahomed, L., Carbonneau, J., Tu, V., Abed, Y., Antiviral Research, 2018, 10.1016/j.antiviral.2018.09.007
Intranasal herpes simplex virus type 2 inoculation causes a profound thymidine kinase dependent cerebral inflammatory response in the mouse hindbrain., Rivest S, Coulombe Z, Boivin G, The European journal of neuroscience, 2002, 10.1046/j.1460-9568.2002.02057.x
Drug resistance patterns of recombinant herpes simplex virus DNA polymerase mutants generated with a set of overlapping cosmids and plasmids., Boivin G, Bestman-Smith J, Journal of virology, 2003, 10.1128/jvi.77.14.7820-7829.2003
Presence of oseltamivir-resistant pandemic A/H1N1 minor variants before drug therapy with subsequent selection and transmission., Boivin G, Papenburg J, Hamelin ME, Fitch A, Pinilla LT, DePasse JV, Holmes EC, Ghedin E, The Journal of infectious diseases, 2012, 10.1093/infdis/jis571
Human parainfluenza 2 related illness and a death in a group of captive western lowland gorillas (gorilla gorilla gorilla), Lair, S., Boivin, G., Abrahamyan, L., Carbonneau, J., Sánchez Mendoza, L.J., Hamelin, M.-E., Desmarchelier, M., Ferrell, S.T., Couture, É.L., Journal of Zoo and Wildlife Medicine, 2019, 10.1638/2018-0237
Low systemic ganciclovir exposure and preemptive treatment failure of cytomegalovirus reactivation in a transplanted child., Ovetchkine P, Boivin G, Tapiéro B, Rousseau C, Duval M, Launay E, Théôret Y, Autmizguine J, Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique, 2011
Household transmission of the 2009 pandemic A/H1N1 influenza virus: elevated laboratory‐confirmed secondary attack rates and evidence of asymptomatic infections., Boivin G, De Serres G, Charest H, Roger M, Hardy I, Skowronski D, Rouleau I, Ouakki M, Carbonneau J, Rhéaume C, Hamelin MÈ, Baz M, Papenburg J, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, 10.1086/656582
Quantification of the influenza virus load by real-time polymerase chain reaction in nasopharyngeal swabs of patients treated with oseltamivir., Wat C, Coulombe Z, Boivin G, The Journal of infectious diseases, 2003, 10.1086/377046
Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by ribavirin and immune serum globulin in vitro., Piedra PA, Boivin G, Jewell AM, Chetty SN, Wyde PR, Antiviral research, 2003, 10.1016/s0166-3542(03)00153-0

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Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2009

Amel Saim Mamoun - Doctorat - En cours
Clémence Vacher - Doctorat - En cours
Lina Lapeyre - Doctorat - En cours
Shella Gilbert-Girard - Post-doctorat - En cours
Philippe Simon - Maîtrise avec mémoire - 2010/09
Mario Andres Pizzorno - Maîtrise avec mémoire - 2011/05
Lady Tatiana Pinilla - Maîtrise avec mémoire - 2012/09
Rafik Menasria - Maîtrise avec mémoire - 2013/05
Julie Ann - Doctorat - 2015/01
Emilien Drouot - Doctorat - 2015/09
Miguel Retamal - Doctorat - 2016/09
Véronique Tu - Maîtrise avec mémoire - 2017/09
Julia Dubois - Doctorat - 2018/01
Martin Pilaev - Maîtrise avec mémoire - 2018/09
Coraline Canivet - Doctorat - 2019/09
Karima Zarrouk - Doctorat - 2021/05
Zeineb M'hamdi - Doctorat - 2021/09
William Enlow - Maîtrise avec mémoire - 2021/09
Olus Uyar - Doctorat - 2022/05
Gabrielle Pageau - Maîtrise avec mémoire - 2023/01
Daniela Alicja Ogonczyk-Makowska - Doctorat - 2024/01
Nicolas Fortin - Maîtrise avec mémoire - 2024/01

Encadrement d'étudiant(e)s pour les programmes suivants :

Microbiologie-immunologie

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*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.

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