Guy Boivin

Impact of Frailty on Influenza Vaccine Effectiveness and Clinical Outcomes: Experience From the Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) Network 2011/12 Season, Shelly A. McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Geoffrey Taylor, Grant Stiver, Daniel Smyth, Stephanie Smith, Vivek Shinde, Makeda Semret, David Richardson, Jeff Powis, Andre Poirier, Allison Mcgeer, Janet E. Mcelhaney, Anne E. Mccarthy, Donna Mackinnon-Cameron, Mark Loeb, Bruce Light, Jason Leblanc, Joanne M. Langley, Philippe Lagace-Wiens, Kevin Katz, Jennie Johnstone, Barbara Ibarguchi, Scott A. Halperin, Francois Haguinet, Todd Hatchette, Karen Green, May Elsherif, Gael Dos Santos, Ayman Chit, William Bowie, Francisco Diaz-Mitoma, Guy Boivin, Ardith Ambrose, Lingyun Ye, Sarah MacDonald, Melissa K. Andrew, Open Forum Infectious Diseases, 2016, 10.1093/ofid/ofw172.573

Cytomegalovirus (CMV) glycoprotein B genotypes and response to antiviral therapy, in solid-organ-transplant recipients with CMV disease., Boivin G, Gilbert C, Kumar D, Humar A, The Journal of infectious diseases, 2003, 10.1086/377002

Influenza drug resistance., Boivin G, Abed Y, Pizzorno A, Seminars in respiratory and critical care medicine, 2011, 10.1055/s-0031-1283281

Antiviral Drugs Against Herpesviruses, Guy Boivin, Jocelyne Piret, Antiviral Drug Discovery and Development, 2021, 10.1007/978-981-16-0267-2_1

Virological features and clinical manifestations associated with human metapneumovirus: a new paramyxovirus responsible for acute respiratory-tract infections in all age groups., Anderson LJ, Erdman DD, Peret TC, Côté S, Moisan D, Ruel L, Pelletier G, Abed Y, Boivin G, The Journal of infectious diseases, 2002, 10.1086/344319

Novel antiviral compounds and combination therapy for influenza viruses,Nouveaux composés antiviraux et thérapie combinée contre les virus influenza, Lina, B., Rosa-Calatrava, M., Boivin, G., Virologie, 2019, 10.1684/vir.2019.0802

International consensus guidelines on the management of cytomegalovirus in solid organ transplantation., Transplantation Society International CMV Consensus Group, Humar A, Allen U, Snydman DR, Chou S, Asberg A, Caliendo AM, Kumar D, Kotton CN, Transplantation, 2010, 10.1097/tp.0b013e3181cee42f

Multi-year study of human metapneumovirus infection at a large US Midwestern Medical Referral Center, Guy Boivin, Sarah E. Starks, Gary V. Doern, Yacine Abed, Newell D. Nobbs, Dean D. Erdman, Sharon F. Setterquist, Ana W. Capuano, Gregory C. Gray, Journal of Clinical Virology, 2006, 10.1016/j.jcv.2006.08.016

Molecular characterization of viruses from clinical respiratory samples producing unidentified cytopathic effects in cell culture., Boivin G, Abed Y, Viruses, 2009, 10.3390/v1020084

Effect of ribavirin and glucocorticoid treatment in a mouse model of human metapneumovirus infection., Boivin G, Prince GA, Hamelin ME, Antimicrobial agents and chemotherapy, 2006, 10.1128/aac.50.2.774-777.2006

Effect of in vitro syncytium formation on the severity of human metapneumovirus disease in a murine model, Boivin, G., Hamelin, M.-È., Couture, C., Lavigne, S., Rhéaume, C., Carbonneau, J., Dubois, J., Cavanagh, M.-H., Aerts, L., PLoS ONE, 2015, 10.1371/journal.pone.0120283

Protective role of CX3CR1 signalling in resident cells of the central nervous system during experimental herpes simplex virus encephalitis, Boivin, G., Gosselin, J., Piret, J., Canivet, C., Menasria, R., Journal of General Virology, 2017, 10.1099/jgv.0.000667

Contagious period for pandemic (H1N1) 2009., Boivin G, Charest H, Couillard M, Bourgault A, Carbonneau J, Li Y, Boulianne N, Flamand L, Skowronski D, Quach C, Hamelin ME, Rouleau I, De Serres G, Emerging infectious diseases, 2010, 10.3201/eid1605.091894

Longitudinal evaluation of herpes simplex virus DNA load during episodes of herpes labialis., Booth T, Keays S, Sergerie Y, Goyette N, Boivin G, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2006, 10.1016/j.jcv.2006.09.006

A collaborative study to establish the 1st WHO International Standard for human cytomegalovirus for nucleic acid amplification technology., Collaborative Study Group, Minor PD, Heath AB, Fryer JF, Biologicals : journal of the International Association of Biological Standardization, 2016, 10.1016/j.biologicals.2016.04.005

Effects of different adjuvants in the context of intramuscular and intranasal routes on humoral and cellular immune responses induced by detergent-split A/H3N2 influenza vaccines in mice, Boivin, G., Papadopoulou, B., Mallett, C., Hamelin, M.-E., Lanteigne, A.-M., Plante, M., Tribout-Jover, P., Zekki, H., Samant, M., Baz, M., Clinical and Vaccine Immunology, 2012, 10.1128/CVI.05441-11

Emergence of an oseltamivir-resistant influenza A/H3N2 Virus in an elderly patient receiving a suboptimal dose of antiviral prophylaxis, Boivin, G., Bouhy, X., Abed, Y., Roussy, J.-F., Journal of Clinical Microbiology, 2013, 10.1128/JCM.02659-13

A trial of valganciclovir prophylaxis for cytomegalovirus prevention in lung transplant recipients., Lien D, Nia S, Jackson K, Fenton J, Siegal D, Boivin G, Kumar D, Preiksaitis J, Humar A, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2005, 10.1111/j.1600-6143.2005.00866.x

Human parainfluenza 2 related illness and a death in a group of captive western lowland gorillas (gorilla gorilla gorilla), Lair, S., Boivin, G., Abrahamyan, L., Carbonneau, J., Sánchez Mendoza, L.J., Hamelin, M.-E., Desmarchelier, M., Ferrell, S.T., Couture, É.L., Journal of Zoo and Wildlife Medicine, 2019, 10.1638/2018-0237

Recent advances in management of genital herpes., Boivin G, Tétrault I, Canadian family physician Medecin de famille canadien, 2000

Discordant phenotypes and genotypes of cytomegalovirus (CMV) in patients with AIDS and relapsing CMV retinitis., Boivin G, Gilbert C, AIDS (London, England), 2003, 10.1097/00002030-200302140-00007

Pre-Omicron seroprevalence, seroconversion, and seroreversion of infection-induced SARS-CoV-2 antibodies among a cohort of children and teenagers in Montréal, Canada, Caroline Quach, Guy Boivin, Jesse Papenburg, Gaston De Serres, Cat Tuong Nguyen, Julie Carbonneau, Margot Barbosa Da Torre, Islem Cheriet, Marie-Ève Hamelin, Britt McKinnon, Adrien Saucier, Laura Pierce, Katia Charland, Kate Zinszer, International Journal of Infectious Diseases, 2023, 10.1016/j.ijid.2023.03.036

Analysis of HHV-6 mutations in solid organ transplant recipients at the onset of cytomegalovirus disease and following treatment with intravenous ganciclovir or oral valganciclovir., Boivin G, Goyette N, Piret J, Bounaadja L, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2013, 10.1016/j.jcv.2013.06.024

Comparison of pandemic and seasonal influenza in the pediatric emergency department., Boivin G, De Serres G, Guimont C, Fontela PS, Ouakki M, Papenburg J, Aguirre E, The Pediatric infectious disease journal, 2011, 10.1097/inf.0b013e3182103d54

Quantitation of cytomegalovirus (CMV) DNA in leukocytes of human immunodeficiency virus-infected subjects with and without CMV disease by using PCR and the SHARP Signal Detection System., Bergeron MG, Lazar JG, Lalonde R, Toma E, Murray G, Handfield J, Boivin G, Journal of clinical microbiology, 1997, 10.1128/jcm.35.2.525-526.1997

Engineering of live chimeric vaccines against human metapneumovirus, Boivin, G., Hamelin, M.-È., Makowska, D.O., Pathogens, 2020, 10.3390/pathogens9020135

Effect of foscarnet on quantities of cytomegalovirus and human immunodeficiency virus in blood of persons with AIDS., Martin-Munley SS, Eaton CA, Crumpacker CS, Shepp DH, Boivin G, Holm MA, Smith SA, Acosta EP, Henry WK, Erice A, Fletcher CV, Balfour HH, Antimicrobial agents and chemotherapy, 1996, 10.1128/aac.40.12.2721

Influenza A(H1N1)pdm09 Virus but Not Respiratory Syncytial Virus Interferes with SARS-CoV-2 Replication during Sequential Infections in Human Nasal Epithelial Cells, Guy Boivin, Jocelyne Piret, Julie Carbonneau, Mathilde Hénaut, Clément Fage, Viruses, 2022, 10.3390/v14020395

Inhibition of the 3CL Protease and SARS-CoV-2 Replication by Dalcetrapib, Jean-Claude Tardif, Fouzia Laghrissi-Thode, Anne Perez, Marie-Eve Picard, Nathalie Goyette, Véronique Lavoie, Rong Shi, Eric Rhéaume, Guy Boivin, Eric Niesor, ACS Omega, 2021, 10.1021/acsomega.1c01797

Characterization of human cytomegalovirus (HCMV) UL97 mutations found in a valganciclovir/oral ganciclovir prophylactic trial by use of a bacterial artificial chromosome containing the HCMV genome., Boivin G, Covington E, Gilbert C, Martin M, The Journal of infectious diseases, 2006, 10.1086/505882

Influenza virus resistance to neuraminidase inhibitors., Boivin G, Abed Y, Pizzorno A, Samson M, Antiviral research, 2013, 10.1016/j.antiviral.2013.03.014

Design considerations in building in silico equivalents of common experimental influenza virus assays., Beauchemin CA, Boivin G, Simon P, Liao LE, Holder BP, Autoimmunity, 2011, 10.3109/08916934.2011.523267

Characterization of drug-resistant influenza virus A(H1N1) and A(H3N2) variants selected in vitro with laninamivir, Boivin, G., Pryor, M.J., Tucker, S.P., Luttick, A., Hamilton, S., Desrochers, F.-M., Abed, Y., Samson, M., Antimicrobial Agents and Chemotherapy, 2014, 10.1128/AAC.03313-14

Delayed but not early glucocorticoid treatment protects the host during experimental herpes simplex virus encephalitis in mice., Rivest S, Gosselin D, Boivin G, Sergerie Y, The Journal of infectious diseases, 2007, 10.1086/511987

Oseltamivir-zanamivir combination therapy is not superior to zanamivir monotherapy in mice infected with influenza A(H3N2) and A(H1N1)pdm09 viruses, Boivin, G., Rhéaume, C., Abed, Y., Pizzorno, A., Antiviral Research, 2014, 10.1016/j.antiviral.2014.02.017

Evaluation of susceptibility of human herpesvirus 8 to antiviral drugs by quantitative real-time PCR., Boivin G, Sergerie Y, Journal of clinical microbiology, 2003, 10.1128/jcm.41.8.3897-3900.2003

Impact of deficiency in CCR2 and CX3CR1 receptors on monocytes trafficking in herpes simplex virus encephalitis., Boivin G, Rivest S, Gosselin D, Menasria R, Boivin N, The Journal of general virology, 2012, 10.1099/vir.0.041046-0

Modified cyclodextrins as broad-spectrum antivirals, Tapparel, C., Stellacci, F., Boivin, G., Kirkegaard, K., Constant, S., Huang, S., Kaiser, L., Král, P., Vuković, L., Han, Y., Constant, D.A., Gasbarri, M., Piret, J., Gasilova, N., Ortiz, D., Janeček, M., Cagno, V., Jones, S.T., Science Advances, 2020, 10.1126/sciadv.aax9318

The Burden of Pneumococcal Community-Acquired Pneumonia and Invasive Pneumococcal Disease in Hospitalized Adults: A Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) Network Study, Shelly A. McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Grant Stiver, Makeda Semret, Sanela Moraca, Allison McGeer, Anne E. McCarthy, Mark Loeb, Jennie Johnstone, Todd Hatchette, Karen Green, William Bowie, Guy Boivin, Melissa K. Andrew, Amanda Lang, Haley Gillis, Irene Martin, Ardith Ambrose, Lingyun Ye, Donna Mackinnon-Cameron, May Elsherif, Jason Leblanc, Open Forum Infectious Diseases, 2016, 10.1093/ofid/ofw194.74

Droplet digital PCR to investigate quasi-species at codons 119 and 275 of the A(H1N1)pdm09 neuraminidase during zanamivir and oseltamivir therapies, Boivin, G., Kaiser, L., L'Huillier, A.G., Abed, Y., Carbonneau, J., Journal of Medical Virology, 2017, 10.1002/jmv.24680

Single-cell transcriptomics of the ventral posterolateral nucleus-enriched thalamic regions from HSV-1-infected mice reveal a novel microglia/microglia-like transcriptional response, Guy Boivin, Jacques Corbeil, Marie-Eve Tremblay, Luc Vallières, Fernando González Ibáñez, Lina Lapeyre, Maude Bordeleau, Juan Manuel Dominguez, Olus Uyar, Journal of Neuroinflammation, 2022, 10.1186/s12974-022-02437-7

Incidence and characterization of cytomegalovirus resistance mutations among pediatric solid organ transplant patients who received valganciclovir prophylaxis., Boivin G, Ives J, Goyette N, Martin M, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2010, 10.1016/j.jcv.2010.01.009

In vitro susceptibility of geographically and temporally distinct Zika viruses to favipiravir and ribavirin, Boivin, G., Kobinger, G.P., Griffin, B.D., Goyette, N., Baz, M., Antiviral Therapy, 2017, 10.3851/IMP3180

Rapid and Technically Simple Detection of SARS-CoV-2 Variants Using CRISPR Cas12 and Cas13, Jacques P. Tremblay, Nathalie Turgeon, Arnaud Droit, Guy Boivin, Jean-Francois Lemay, Gary Kobinger, Anthony Guedon, Patrik Quessy, Thierry Vincent, Charles Joly Beauparlant, Julie Carbonneau, Gabriel Lamothe, The CRISPR Journal, 2023, 10.1089/crispr.2023.0007

Distribution and clinical impact of human respiratory syncytial virus genotypes in hospitalized children over 2 winter seasons., Boivin G, Dery P, Bergeron MG, Leblanc E, Vachon ML, Tremblay M, De Serres G, Gilca R, The Journal of infectious diseases, 2005, 10.1086/498526

Avian Cell Line DuckCelt®-T17 Is an Efficient Production System for Live-Attenuated Human Metapneumovirus Vaccine Candidate Metavac®, Manuel Rosa-calatrava, Julia Dubois, Guy Boivin, Olivier Terrier, Marie-Eve Hamelin, karen moreau, Jean-François ELéouët, Bruno Lina, Marie Galloux, Thomas Julien, Emilie Laurent, Victoria Dulière, Cédrine Milesi, Blandine PADEY, Daniela Ogonczyk-Makowska, Pauline Brun, Aurelien Traversier, Andrés Pizzorno, Caroline Chupin, Vaccines, 2021, 10.3390/vaccines9101190

The prophylactic administration of a monoclonal antibody against human metapneumovirus attenuates viral disease and airways hyperresponsiveness in mice., Boivin G, Ulbrandt N, Suzich J, Kiener P, Sackett M, Couture C, Hamelin ME, Antiviral therapy, 2008

Influenza virus epidemiology: A permanent vaccine challenge,Épidémiologie des virus influenza: Le défi vaccinal permanent, Lina, B., Boivin, G., Virologie, 2019, 10.1684/vir.2019.0788

Predicting major clinical events among Canadian adults with laboratory-confirmed influenza infection using the influenza severity scale, Duncan Webster, Louis Valiquette, Daniel Smyth, Geoff Taylor, Stephanie Smith, Makeda Semret, David Richardson, Jeff Powis, Andre Poirier, Anne McCarthy, Bruce Light, Phillipe Lagacé-Wiens, Kevin Katz, Mark Loeb, Jennie Johnstone, Allison McGeer, Karen Green, William Bowie, Grant Stiver, Chris Verschoor, Francisco Diaz-Mitoma, Sylvie Trottier, Guy Boivin, the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN), Melissa K. Andrew, Shelly A. McNeil, Todd F. Hatchette, May ElSherif, Jason J. LeBlanc, Henrique Pott, Scientific Reports, 2024, 10.1038/s41598-024-67931-9

Treatment with a novel topical nanoemulsion (NB-001) speeds time to healing of recurrent cold sores, Baker, J.R., Stanberry, L.R., Boivin, G., Sutcliffe, J., Ciotti, S., Ijzerman, M., Flack, M.R., Jarratt, M., Jones, T.M., Kircik, L., Journal of Drugs in Dermatology, 2012

The need for validation of statistical methods for estimating respiratory virus-attributable hospitalization., Buckeridge DL, Boivin G, Skowronski D, De Serres G, Gilca R, American journal of epidemiology, 2009, 10.1093/aje/kwp195

Older Age and Frailty Are Associated With Higher Mortality but Lower Intensive Care Unit Admission Among Adults Admitted to Canadian Hospitals With COVID-19: A Report From the Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance Network, McNeil S, Loeb M, Trottier S, Ambrose A, MacKinnon-Cameron D, ElSherif M, Hatchette TF, McElhaney JE, Valiquette L, Boivin G, LeBlanc J, Godin J, Andrew M, 2021, 10.2139/ssrn.3844895

Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and management., Boivin G, Piret J, Antimicrobial agents and chemotherapy, 2010, 10.1128/aac.00615-10

Influenza virus shedding: excretion patterns and effects of antiviral treatment., Boivin G, Aoki FY, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2009, 10.1016/j.jcv.2009.01.010

Reinfection with SARS-CoV-2 in a patient undergoing chemotherapy for lymphoma: Case report, Guy Boivin, Martin A Smith, Marieke Rozendaal, Antoine Chiasson, Julie Carbonneau, Marie-Ève Hamelin, Shawn M Simpson, Marie Gourdeau, Julie Bestman-Smith, Florence Côté, Official Journal of the Association of Medical Microbiology and Infectious Disease Canada, 2022, 10.3138/jammi-2021-0036

Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy., Boivin G, Bestman-Smith J, Journal of medical virology, 2002, 10.1002/jmv.2195

Emergence and prevalence of cytomegalovirus UL97 mutations associated with ganciclovir resistance in AIDS patients., Boivin G, Bergeron MG, Lalonde R, Toma E, Handfield J, Gilbert C, AIDS (London, England), 1998, 10.1097/00002030-199802000-00001

Human metapneumovirus, Peru., Boivin G, Abed Y, McCarthy T, Lebeck MG, Olson J, Neville JS, Sanchez JL, Setterquist SF, Capuano AW, Gray GC, Emerging infectious diseases, 2006, 10.3201/eid1202.051133

Targeted Proteomics of Human Metapneumovirus in Clinical Samples and Viral Cultures, Moseley, M.A., Corbeil, J., Boivin, G., Plante, P.-L., Robitaille, L., Gerhardt, G., Foster, M.W., Analytical Chemistry, 2015, 10.1021/acs.analchem.5b01544

A Candidate Therapeutic Monoclonal Antibody Inhibits Both HRSV and HMPV Replication in Mice, Gary P. Kobinger, Marc-André D’Aoust, Guy Boivin, Marie-Ève Ouellet, Pierre-Olivier Lavoie, Liva Checkmahomed, Marie-Christine Venable, Julie Carbonneau, Marie-Eve Hamelin, Hugues Fausther-Bovendo, Biomedicines, 2022, 10.3390/biomedicines10102516

Intrahost dynamics of antiviral resistance in influenza a virus reflect complex patterns of segment linkage, reassortment, and natural selection, Ghedina, E., Boivin, G., Holmes, E.C., Cui, L., Twaddle, A., Fitch, A., Hamelin, M.-E., Greenbaum, B.D., Sebra, R., Song, T., Rogers, M.B., mBio, 2015, 10.1128/mBio.02464-14

Management of Cytomegalovirus Infections in the Era of the Novel Antiviral Players, Letermovir and Maribavir, Guy Boivin, Jocelyne Piret, Infectious Disease Reports, 2024, 10.3390/idr16010005

Human metapneumovirus: enhanced pulmonary disease in cotton rats immunized with formalin-inactivated virus vaccine and challenged., Prince GA, Porter DD, Boivin G, Hamlin ME, Blanco JC, Boukhvalova MS, Cragin RP, Yim KC, Vaccine, 2007, 10.1016/j.vaccine.2007.04.075

Influenza A Virus Interferes With Respiratory Syncytial Virus in Mice and Reconstituted Human Airway Epithelium, Guy Boivin, Christian Couture, Nathalie Goyette, Julie Carbonneau, Chantal Rhéaume, Jocelyne Piret, Shella Gilbert-Girard, 1911, 10.1101/2025.02.19.639117

Treatment of COVID-19 symptoms with over the counter (OTC) medicines used for treatment of common cold and flu, Rangaraj Selvarangan, Andrew Pavia, Benjamin J Cowling, Guy Boivin, Ronald Eccles, Clinical Infection in Practice, 2023, 10.1016/j.clinpr.2023.100230

Rate of emergence of cytomegalovirus (CMV) mutations in leukocytes of patients with acquired immunodeficiency syndrome who are receiving valganciclovir as induction and maintenance therapy for CMV retinitis., Roberts NA, Sudlow R, Greenfield I, Gaudreau A, Gilbert C, Boivin G, The Journal of infectious diseases, 2001, 10.1086/324672

Zika-Induced Male Infertility in Mice Is Potentially Reversible and Preventable by Deoxyribonucleic Acid Immunization, Boivin, G., Kobinger, G.P., Weiner, D.B., Muthumani, K., Kim, J.J., Sardesai, N.Y., Maslow, J.N., Roberts, C.C., Park, Y.K., Magalhães, K.G., Tremblay, R.R., Das Neves Almeida, R., Couture, C., Carbonneau, J., Venable, M.-C., Rhéaume, C., Griffin, B.D., Piret, J., De La Vega, M.-A., Journal of Infectious Diseases, 2019, 10.1093/infdis/jiy336

Human Respiratory Syncytial Virus-Induced Immune Signature of Infection Revealed by Transcriptome Analysis of Clinical Pediatric Nasopharyngeal Swab Samples, Rosa-Calatrava, M., Terrier, O., Legras-Lachuer, C., Boivin, G., Textoris, J., Roche, M., Hamelin, M.-E., Lina, B., Orcel, E., Carbonneau, J., Traversier, A., Julien, T., Padey, B., Dubois, J., Pizzorno, A., Nicolas De Lamballerie, C., Journal of Infectious Diseases, 2021, 10.1093/infdis/jiaa468

Diagnosis of viral infections, Petric, M., Mazzulli, T., Boivin, G., Clinical Virology, 2016, 10.1128/9781555819439.ch15

Prophylactic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H274Y neuraminidase mutation., Boivin G, Simon P, Abed Y, Antimicrobial agents and chemotherapy, 2010, 10.1128/aac.01681-09

Infiltration pattern of blood monocytes into the central nervous system during experimental herpes simplex virus encephalitis, Boivin, G., Piret, J., Canivet, C., Menasria, R., PLoS ONE, 2015, 10.1371/journal.pone.0145773

The REinfection in COVID-19 Estimation of Risk (RECOVER) study: Reinfection and serology dynamics in a cohort of Canadian healthcare workers, Caroline Quach, Gaston De Serres, Jacques Corbeil, Vladimir Gilca, Sabryna Nantel, Benoîte Bourdin, Kelsey Adams, Fazia Tadount, Marie-Ève Hamelin, Matthew P. Cheng, Patrice Savard, Hélène Decaluwe, Deirde McCormack, Yves Longtin, Guy Boivin, Étienne Racine, 2022, 10.1101/2022.02.10.22269967

Detection and management of antiviral resistance for influenza viruses, Boivin, G., Influenza and other Respiratory Viruses, 2013, 10.1111/irv.12176

DNA vaccination protects mice against Zika virus-induced damage to the testes, Kobinger, G.P., Weiner, D.B., Safronetz, D., Embury-Hyatt, C., Kobasa, D., Booth, S.A., Boivin, G., Lindsay, R., Bello, A., Yao, X.-J., Kim, J.J., Sardesai, N.Y., Maslow, J.N., Park, Y.K., Smid, V., McTavish, G., Scott, J., Scharikow, L., Soule, G., De Graff, C., Frost, K.L., Tran, K.N., Kucas, S., Piret, J., De La Vega, M.-A., Racine, T., Ranadheera, C., Stein, D.R., Majer, A., Hagan, M., Audet, J., Warner, B.M., Muthumani, K., Griffin, B.D., Nature Communications, 2017, 10.1038/ncomms15743

Reduced susceptibility to neuraminidase inhibitors in influenza b isolate, Canada, Boivin, G., Vinh, D.C., Papenburg, J., Carbonneau, J., Lagüe, P., Fage, C., Abed, Y., Emerging Infectious Diseases, 2019, 10.3201/EID2504.181554

An Early Microglial Response Is Needed to Efficiently Control Herpes Simplex Virus Encephalitis, Boivin, G., Rivest, S., Zarrouk, K., Carbonneau, J., Venable, M.-C., Piret, J., Laflamme, N., Uyar, O., Journal of Virology, 2020, 10.1128/JVI.01428-20

Characterization of multidrug-resistant influenza A/H3N2 viruses shed during 1 year by an immunocompromised child., Boivin G, McDonald J, Abed Y, Baz M, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, 10.1086/508777

Cross-reactive antibody to swine influenza A(H3N2) subtype virus in children and adults before and after immunisation with 2010/11 trivalent inactivated influenza vaccine in Canada, August to November 2010., Boivin G, Rhéaume C, Hamelin ME, Dionne M, Gilca V, Gardy JL, Janjua NZ, De Serres G, Skowronski DM, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2012, 10.2807/ese.17.04.20066-en

Viral interference between severe acute respiratory syndrome coronavirus 2 and influenza A viruses, Guy Boivin, Nathalie Goyette, Mathilde Hénaut, Julie Carbonneau, Jocelyne Piret, Shella Gilbert-Girard, PLOS Pathogens, 2024, 10.1371/journal.ppat.1012017

Influenza vaccine effectiveness against influenza-related hospitalization during a season with mixed outbreaks of four influenza viruses: A test-negative case-control study in adults in Canada, McNeil, S.A., Ye, L., Webster, D., Valiquette, L., Trottier, S., Stiver, G., Semret, M., Richardson, D., Powis, J., Nichols, M.K., McGeer, A., McElhaney, J., McCarthy, A., MacKinnon-Cameron, D., Loeb, M., LeBlanc, J., Langley, J.M., Katz, K., Johnstone, J., Ibarguchi, B., Halperin, S.A., Haguinet, F., Green, K., ElSherif, M., Dos Santos, G., Chit, A., Bowie, W., Boivin, G., Ambrose, A., Hatchette, T., Shinde, V., Andrew, M.K., BMC Infectious Diseases, 2017, 10.1186/s12879-017-2905-8

Impact of Amino Acid Substitutions in Region II and Helix K of HSV-1 and HCMV DNA Polymerases on Resistance to Foscarnet., Boivin G, Shi R, Piret J, Goyette N, Pham VD, Zhu X, Zarrouk K, Antimicrobial agents and chemotherapy, 2021, 10.1128/aac.00390-21

Effect of pretreatment with toll-like receptor agonists in a mouse model of herpes simplex virus type 1 encephalitis., Boivin G, Rivest S, Sergerie Y, Boivin N, The Journal of infectious diseases, 2008, 10.1086/590671

Role of helix P of the human cytomegalovirus DNA polymerase in resistance and hypersusceptibility to the antiviral drug foscarnet., Götte M, Boivin G, Gilbert C, Tchesnokov EP, Journal of virology, 2006, 10.1128/jvi.80.3.1440-1450.2006

Molecular and epidemiologic investigation of a rhinovirus outbreak in a neonatal intensive care unit, Papenburg, J., Lefebvre, M.-A., Boivin, G., Beltempo, M., Fontela, P.S., Caya, C., Quach, C., Lafond, M., Carbonneau, J., Isabel, S., El Idrissi, K.R., Infection Control and Hospital Epidemiology, 2019, 10.1017/ice.2018.311

Clinical impact of ganciclovir-resistant cytomegalovirus infections in solid organ transplant patients., Covington E, Humar A, Gilbert C, Goyette N, Boivin G, Transplant infectious disease : an official journal of the Transplantation Society, 2005, 10.1111/j.1399-3062.2005.00112.x

Characterization of human metapneumoviruses isolated from patients in North America., Anderson LJ, Erdman DD, Osterhaus AD, Humphrey C, Couillard M, Li Y, Boivin G, Peret TC, The Journal of infectious diseases, 2002, 10.1086/340518

Syncytium formation and HIV-1 replication are both accentuated by purified influenza and virus-associated neuraminidase., Tremblay MJ, Goyette N, Boivin G, Sato S, Barbeau B, Sun J, The Journal of biological chemistry, 2002, 10.1074/jbc.m110764200

Norwalk-like gastroenteritis epidemic in a teaching hospital--Quebec., Courtinat Y, Murray G, Boivin G, Canada diseases weekly report = Rapport hebdomadaire des maladies au Canada, 1990

Droplet Digital PCR and Immunohistochemistry Techniques to Detect Zika Virus in the Central Nervous System of Mice, Boivin, G., Piret, J., Enlow, W., Methods in Molecular Biology, 2020, 10.1007/978-1-0716-0581-3_4

Expression of the late cytomegalovirus (CMV) pp150 transcript in leukocytes of AIDS patients is associated with a high viral DNA load in leukocytes and presence of CMV DNA in plasma., Bergeron MG, Lalonde R, Toma E, Handfield J, Boivin G, The Journal of infectious diseases, 1999, 10.1086/314721

Effects of different drug combinations in immunodeficient mice infected with an influenza a/h3n2 virus, Baz, M., Boivin, G., Kobinger, G., Abed, Y., Venable, M.-C., Carbonneau, J., Uyar, O., Fausther-Bovendo, H., Mhamdi, Z., Microorganisms, 2020, 10.3390/microorganisms8121968

Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its smallhydrophobic protein which plays adetrimental role during infection in mice, Boivin, G., Hamelin, M.E., Rosa-Calatrava, M., Pizzorno, A., Uyar, O., Cavanagh, M.H., Couture, C., Dubois, J., Le, V.B., PLoS Pathogens, 2019, 10.1371/journal.ppat.1007689

The I222V neuraminidase mutation has a compensatory role in replication of an oseltamivir-resistant influenza virus A/H3N2 E119V mutant., Boivin G, Beauchemin CA, Abed Y, Bouhy X, Holder BP, Simon P, Journal of clinical microbiology, 2010, 10.1128/jcm.01732-10

Molecular evolution of influenza A/H3N2 viruses in the province of Québec (Canada) during the 1997-2000 period., Boivin G, Goyette N, Coulthart MB, Hardy I, Li Y, Virus research, 2001, 10.1016/s0168-1702(01)00269-6

Influenza virus susceptibility and resistance to oseltamivir., Roberts N, Boivin G, Aoki FY, Antiviral therapy, 2007

Emergence of oseltamivir-resistant pandemic H1N1 virus during prophylaxis., Boivin G, Hamelin ME, Bouhy X, Papenburg J, Abed Y, Baz M, The New England journal of medicine, 2009, 10.1056/nejmc0910060

Clinical development of letermovir and maribavir: Overview of human cytomegalovirus drug resistance, Boivin, G., Piret, J., Antiviral Research, 2019, 10.1016/j.antiviral.2019.01.011

Immunomodulatory strategies in herpes simplex virus encephalitis, Boivin, G., Piret, J., Clinical Microbiology Reviews, 2020, 10.1128/CMR.00105-19

Antiviral agents in development for zika virus infections, Boivin, G., Baz, M., Pharmaceuticals, 2019, 10.3390/ph12030101

Novel method based on real-time cell analysis for drug susceptibility testing of herpes simplex virus and human cytomegalovirus, Boivin, G., Goyette, N., Piret, J., Journal of Clinical Microbiology, 2016, 10.1128/JCM.03274-15

Drug-resistant herpesviruses: should we look for them?, Boivin G, European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1998, 10.1007/bf01708615

The I427T neuraminidase (NA) substitution, located outside the NA active site of an influenza A(H1N1)pdm09 variant with reduced susceptibility to NA inhibitors, alters NA properties and impairs viral fitness, Boivin, G., Lagüe, P., Fage, C., Carbonneau, J., Barbeau, X., Tu, V., Abed, Y., Antiviral Research, 2017, 10.1016/j.antiviral.2016.11.007

Assessing the diagnostic accuracy of PCR-based detection of Streptococcus pneumoniae from nasopharyngeal swabs collected for viral studies in Canadian adults hospitalised with community-acquired pneumonia: A Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research (CIRN) study, Stiver, G., Bowie, W., Johnstone, J., Loeb, M., McGeer, A., McCarthy, A., Semret, M., Valiquette, L., Boivin, G., Trottier, S., Webster, D., Andrew, M., LeBlanc, J.J., McNeil, S.A., Hatchette, T.F., Martin, I., Elsherif, M., Lang, A.L.S., Gillis, H.D., BMJ Open, 2017, 10.1136/bmjopen-2016-015008

A review of influenza vaccine immunogenicity and efficacy in HIV-infected adults., Halperin S, Boivin G, Klein MB, Mills E, Fergusson D, Hutton B, Cooper C, The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2008, 10.1155/2008/419710

Resistance of Herpesviruses to Antiviral Agents, W. L. Drew, G. Boivin, Antimicrobial Resistance and Implications for the Twenty-First Century, 1911, 10.1007/978-0-387-72418-8_8

Infectivity of healthcare workers diagnosed with SARS-CoV-2 infection approximately 2 weeks after onset of symptoms: A cross-sectional study, de Serres, G., Roger, M., Villeneuve, J., Farfard, J., Boivin, G., Baz, M., Savard, P., Quach, C., Charest, H., Longtin, Y., Infection Control and Hospital Epidemiology, 2020, 10.1017/ice.2020.1420

Management and prevention of herpes zoster: A Canadian perspective., Patrick DM, Elliott CT, Jovey R, Boivin G, The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2010, 10.1155/2010/178036

Activity of the oral neuraminidase inhibitor A-322278 against the oseltamivir-resistant H274Y (A/H1N1) influenza virus mutant in mice., Boivin G, Nehmé B, Abed Y, Baz M, Antimicrobial agents and chemotherapy, 2008, 10.1128/aac.01276-08

Pandemics Throughout History, Boivin, G., Piret, J., Frontiers in Microbiology, 2021, 10.3389/fmicb.2020.631736

Human respiratory syncytial virus and other viral infections in infants receiving palivizumab., De Serres G, Ouakki M, Carbonneau J, Frenette L, Caouette G, Boivin G, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2008, 10.1016/j.jcv.2007.11.012

Acyclovir susceptibilities of herpes simplex virus strains isolated from solid organ transplant recipients after acyclovir or ganciclovir prophylaxis., Balfour HH, Dunn DL, Crane DD, Erice A, Boivin G, Antimicrobial agents and chemotherapy, 1993, 10.1128/aac.37.2.357

Characterization of cellular transcriptomic signatures induced by different respiratory viruses in human reconstituted airway epithelia, Rosa-Calatrava, M., Terrier, O., Boivin, G., Lina, B., Legras-Lachuer, C., Traversier, A., Bouveret, M., Padey, B., Julien, T., Dubois, J., Pizzorno, A., Nicolas de Lamballerie, C., Scientific Reports, 2019, 10.1038/s41598-019-48013-7

Neurovirulence and latency of drug-resistant clinical herpes simplex viruses in animal models., Boivin G, Sergerie Y, Canas J, Miles B, Yim K, Martin M, Dambrosi S, Journal of medical virology, 2010, 10.1002/jmv.21773

Neuraminidase-inhibitor resistance testing for pandemic influenza A (H1N1) 2009 in Ontario, Canada., Gubbay J, Boivin G, Low D, Li Y, Bastien N, Lee C, Sarabia A, Tran D, Doyle J, Olsha R, Alexander D, Higgins R, Lombos E, Eshaghi A, Patel S, Longtin J, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2011, 10.1016/j.jcv.2010.12.007

Impact of Prior Season Influenza Vaccination on Seasonal Influenza Vaccine Effectiveness: An Analysis over Four Consecutive Seasons from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN), Shelly McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Daniel Smyth, Vivek Shinde, Rohita Sharma, Makeda Semret, David Richardson, Jeff Powis, Allison Mcgeer, Janet Mcelhaney, Anne Mccarthy, Donna Mackinnon-Cameron, Mark Loeb, Jason Leblanc, Kevin Katz, Francois Haguinet, Karen Green, May Elsherif, Gael Dos Santos, William R Bowie, Guy Boivin, Ardith Ambrose, Todd Hatchette, Melissa K Andrew, Lingyun Ye, Michaela Nichols, Open Forum Infectious Diseases, 2017, 10.1093/ofid/ofx163.1152

Molecular pathway of influenza pan-neuraminidase inhibitor resistance in an immunocompromised patient, Boivin, G., Kaiser, L., Goncalves, A.R., Giannotti, F., Fage, C., Venable, M.-C., Carbonneau, J., Checkmahomed, L., Schibler, M., Abed, Y., Antiviral Therapy, 2020, 10.3851/imp3344

The 2009 pandemic H1N1 D222G hemagglutinin mutation alters receptor specificity and increases virulence in mice but not in ferrets, Boivin, G., Kobasa, D., Couture, C., Joubert, P., Leung, A., Hamelin, M.-E., Pizzorno, A., Abed, Y., Journal of Infectious Diseases, 2011, 10.1093/infdis/jir483

Burden of vaccine-preventable pneumococcal disease in hospitalized adults: A Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) network study, McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Stiver, G., Semret, M., Moraca, S., McGeer, A., McCarthy, A., Loeb, M., Johnstone, J., Green, K., Bowie, W., Boivin, G., Andrew, M.K., Martin, I., Gillis, H., Lang, A.L., Hatchette, T.F., Ambrose, A., Li, L., MacKinnon-Cameron, D., Ye, L., ElSherif, M., LeBlanc, J.J., Vaccine, 2017, 10.1016/j.vaccine.2017.05.049

Sequence analysis of the N, P, M and F genes of Canadian human metapneumovirus strains., Li Y, Anderson LJ, Boivin G, Peret TC, Ward D, Taylor T, Normand S, Bastien N, Virus research, 2003, 10.1016/s0168-1702(03)00065-0

Both TRIF and IPS-1 adaptor proteins contribute to the cerebral innate immune response against herpes simplex virus 1 infection., Boivin G, Gosselin J, Piret J, Lebel M, Boivin N, Menasria R, Journal of virology, 2013, 10.1128/jvi.00591-13

A nasally administered trivalent inactivated influenza vaccine is well tolerated, stimulates both mucosal and systemic immunity, and potentially protects against influenza illness., Fries L, Boivin G, Alexander M, Papp K, Dzongowski P, Lasko B, White L, Shu D, Gorfinkel I, Stiver G, Angel JB, McGeer A, Ward BJ, Aoki F, Langley JM, Vaccine, 2011, 10.1016/j.vaccine.2010.12.100

Diagnosis of Viral Infections*, , Clinical Virology, Third Edition, 2009, 10.1128/9781555815981.ch13

Evolution of surface and nonstructural-1 genes of influenza B viruses isolated in the Province of Québec, Canada, during the 1998-2001 period., Boivin G, Li Y, Coulthart MB, Abed Y, Virus genes, 2003, 10.1023/a:1025768308631

Systematic review of influenza resistance to the neuraminidase inhibitors., Thabane L, Boivin G, Awad T, Thorlund K, BMC infectious diseases, 2011, 10.1186/1471-2334-11-134

Evaluation of Epstein-Barr virus, human herpesvirus 6 (HHV-6), and HHV-8 antiviral drug susceptibilities by use of real-time-PCR-based assays., Boivin G, Goyette N, Piret J, Bounaadja L, Journal of clinical microbiology, 2013, 10.1128/jcm.03234-12

Inhibition of human metapneumovirus replication by small interfering RNA., Boivin G, Johnson PH, Quay SC, Templin MV, Seth S, Ge Q, Cui K, Goyette N, Cavanagh MH, Deffrasnes C, Antiviral therapy, 2008

Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade, Boivin, G., Hamelin, M.-T., De Serres, G., Williams, J.V., Bergeron, M.G., Isabel, S., Carbonneau, J., Papenburg, J., Journal of Clinical Virology, 2013, 10.1016/j.jcv.2013.08.029

Heterosubtypic protection conferred by the human monoclonal antibody PN-SIA28 against influenza A virus lethal infections in mice., Boivin G, Burioni R, Clementi M, Mancini N, Clementi N, Cappelletti F, Rhéaume C, Abed Y, Retamal M, Antimicrobial agents and chemotherapy, 2015, 10.1128/aac.00118-15

A novel effective live-attenuated human metapneumovirus vaccine candidate produced in the serum-free suspension DuckCelt®-T17 cell platform, Manuel Rosa-calatrava, Julia Dubois, Guy Boivin, Olivier Terrier, Marie-Eve Hamelin, karen moreau, Jean-François ELéouët, Bruno Lina, Marie Galloux, Thomas Julien, Emilie Laurent, Victoria Dulière, Cédrine Milesi, Blandine PADEY, Daniela Ogonczyk-Makowska, pauline brun, Aurelien Traversier, Andrés Pizzorno, Caroline Chupin, 1911, 10.1101/2021.08.30.458186

Multiplex real-time PCR assay for detection of influenza and human respiratory syncytial viruses., Bergeron MG, De Serres G, Déry P, Côté S, Boivin G, Journal of clinical microbiology, 2004, 10.1128/jcm.42.1.45-51.2004

Comparative evaluation of the cytomegalovirus DNA load in polymorphonuclear leukocytes and plasma of human immunodeficiency virus-infected subjects., Bergeron MG, Lalonde R, Murray G, Toma E, Handfield J, Boivin G, The Journal of infectious diseases, 1998, 10.1086/514190

Influenza vaccine effectiveness to prevent influenza-related hospitalizations and serious outcomes in Canadian adults over the 2011/12 through 2013/14 influenza seasons: A pooled analysis from the Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS Network), McNeil, S.A., Ye, L., Webster, D., Valiquette, L., Trottier, S., Taylor, G., Stiver, G., Smyth, D., Smith, S., Shinde, V., Semret, M., Schuind, A., Richardson, D., Powis, J., Poirier, A., McGeer, A., McElhaney, J.E., McCarthy, A., MacKinnon-Cameron, D., Loeb, M., LeBlanc, J., Langley, J.M., Lagacé-Wiens, P., Katz, K., Johnstone, J., Ibarguchi, B., Halperin, S.A., Haguinet, F., Green, K., ElSherif, M., Dos Santos, G., Chit, A., Bowie, W., Boivin, G., Ambrose, A., Hatchette, T.F., Andrew, M.K., Nichols, M.K., Vaccine, 2018, 10.1016/j.vaccine.2018.02.093

Comprehensive Herpesviruses Antiviral drug Resistance Mutation Database (CHARMD), sophie Alain, Sébastien Hantz, Detlef Michel, María Ángeles Marcos, Hans H. Hirsch, Graciela Andrei, Tiziana Lazzarotto, Fausto Baldanti, Guy Boivin, William D. Rawlinson, Sunwen Chou, Emilien Bisserier, Lisa Laplace, Daniel Diaz Gonzalez, Valentin Tilloy, Antiviral Research, 2024, 10.1016/j.antiviral.2024.106016

Absence of cytomegalovirus-resistance mutations after valganciclovir prophylaxis, in a prospective multicenter study of solid-organ transplant recipients., Covington E, Freeman R, Alexander B, Blumberg E, Washburn K, Dominguez E, Humar A, Pescovitz MD, Paya C, Macey K, Roberts N, Gilbert C, Goyette N, Boivin G, The Journal of infectious diseases, 2004, 10.1086/382753

Reduced airborne transmission of oseltamivir-resistant pandemic A/H1N1 virus in ferrets., Boivin G, Dubé K, Mallett C, Beaulieu E, Bouhy X, Baz M, Hamelin ME, Antiviral therapy, 2011, 10.3851/imp1794

Herpesvirus DNA polymerases: Structures, functions and inhibitors, Boivin, G., Piret, J., Zarrouk, K., Virus Research, 2017, 10.1016/j.virusres.2017.01.019

The H275Y neuraminidase mutation of the pandemic A/H1N1 influenza virus lengthens the eclipse phase and reduces viral output of infected cells, potentially compromising fitness in ferrets., Beauchemin CA, Boivin G, Abed Y, Holder BP, Pinilla LT, Journal of virology, 2012, 10.1128/jvi.07244-11

Characterization of the DNA polymerase and thymidine kinase genesof herpes simplex virus isolates from AIDS patients in whom acyclovirand foscarnet therapy sequentially failed., Boivin G, Schmit I, The Journal of infectious diseases, 1999, 10.1086/314900

Molecular and antigenic evolution of human influenza A/H3N2 viruses in Quebec, Canada, 2009-2011, Boivin, G., Hamelin, M.-T., Rhéaume, C., Bouhy, X., Papenburg, J., Ann, J., Journal of Clinical Virology, 2012, 10.1016/j.jcv.2011.09.016

Valacyclovir combined with artesunate or rapamycin improves the outcome of herpes simplex virus encephalitis in mice compared to antiviral therapy alone, Boivin, G., Piret, J., Rhéaume, C., Menasria, R., Canivet, C., Antiviral Research, 2015, 10.1016/j.antiviral.2015.09.007

Artesunate demonstrates in vitro synergism with several antiviral agents against human cytomegalovirus., Boivin G, Piret J, Drouot E, Antiviral therapy, 2016, 10.3851/imp3028

Repurposing of drugs as novel influenza inhibitors from clinical gene expression infection signatures, Rosa-Calatrava, M., Boivin, G., Textoris, J., Legras-Lachuer, C., Lina, B., Poissy, J., Escuret, V., Croze, S., Rhéaume, C., Hamelin, M.-E., Roche, M., Traversier, A., Padey, B., Julien, T., de Lamballerie, C.N., Terrier, O., Pizzorno, A., Frontiers in Immunology, 2019, 10.3389/fimmu.2019.00060

Microglia are involved in phagocytosis and extracellular digestion during Zika virus encephalitis in young adult immunodeficient mice, Guy Boivin, Marie-Eve Tremblay, Julie Carbonneau, Nathalie Goyette, Marie-Christine Venable, Olus Uyar, Fernando González Ibáñez, Jocelyne Piret, Maude Bordeleau, William Enlow, Journal of Neuroinflammation, 2021, 10.1186/s12974-021-02221-z

Impact of the Baloxavir-Resistant Polymerase Acid I38T Substitution on the Fitness of Contemporary Influenza A(H1N1)pdm09 and A(H3N2) Strains, Boivin, G., Abed, Y., Baz, M., Venable, M.-C., Carbonneau, J., M'hamdi, Z., Checkmahomed, L., The Journal of infectious diseases, 2020, 10.1093/infdis/jiz418

Clearance of cytomegalovirus viremia after initiation of highly active antiretroviral therapy., LeBlanc RP, Boivin G, The Journal of infectious diseases, 2000, 10.1086/315358

[The emergence of viruses resistant to antiviral agents: a new challenge]., Boivin G, L'union medicale du Canada, 1993

Intranasal herpes simplex virus type 2 inoculation causes a profound thymidine kinase dependent cerebral inflammatory response in the mouse hindbrain., Rivest S, Coulombe Z, Boivin G, The European journal of neuroscience, 2002, 10.1046/j.1460-9568.2002.02057.x

Resistance of Herpesviruses to Antiviral Agents, Guy Boivin, Jocelyne Piret, William L. Drew, Antimicrobial Resistance in the 21st Century, 2018, 10.1007/978-3-319-78538-7_8

Antiviral susceptibilities and analysis of UL97 and DNA polymerase sequences of clinical cytomegalovirus isolates from immunocompromised patients., Chou S, Boivin G, Hanson MN, Sannerud KJ, Balfour HH, Pérez JL, Gil-Roda C, Erice A, The Journal of infectious diseases, 1997, 10.1086/516446

Characterization of drug-resistant recombinant influenza A/H1N1 viruses selected in vitro with peramivir and zanamivir., Boivin G, Abed Y, Baz M, Antiviral research, 2006, 10.1016/j.antiviral.2006.10.012

Long-term impairment of Streptococcus pneumoniae lung clearance is observed after initial infection with influenza A virus but not human metapneumovirus in mice, Boivin, G., Hamelin, M.E., Aerts, L., Ludewick, H.P., Journal of General Virology, 2011, 10.1099/vir.0.030825-0

Contrasting effects on ganciclovir susceptibility and replicative capacity of two mutations at codon 466 of the human cytomegalovirus UL97 gene., Boivin G, Goyette N, Martin M, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2010, 10.1016/j.jcv.2010.08.008

The REinfection in COVID‐19 Estimation of Risk (RECOVER) study: Reinfection and serology dynamics in a cohort of Canadian healthcare workers, Caroline Quach‐Thanh, Gaston De Serres, Jacques Corbeil, Vladimir Gilca, Sabryna Nantel, Benoîte Bourdin, Kelsey Adams, Fazia Tadount, Julie Carbonneau, Marie‐Ève Hamelin, Matthew P. Cheng, Patrice Savard, Hélène Decaluwe, Deirdre McCormack, Yves Longtin, Guy Boivin, Étienne Racine, Influenza and Other Respiratory Viruses, 2022, 10.1111/irv.12997

Mapping and characterization of the primary and anamnestic H-2(d)-restricted cytotoxic T-lymphocyte response in mice against human metapneumovirus., Polack FP, Kleeberger SR, Collins PL, Boivin G, Buchholz UJ, Zavala F, Melendi GA, Journal of virology, 2007, 10.1128/jvi.02423-06

Human herpesvirus 8 infection of the genital tract of HIV-seropositive and HIV-seronegative women at risk of sexually transmitted diseases. Canadian Women's HIV Study Group., Coutlée F, Forest P, Gaudreau A, Walmsley S, Lapointe N, Hankins C, Boivin G, AIDS (London, England), 2000, 10.1097/00002030-200005260-00028

Treatment with a novel topical nanoemulsion (NB-001) speeds time to healing of recurrent cold sores., NB-001 Study Group, Baker JR, Stanberry LR, Boivin G, Sutcliffe J, Ciotti S, Ijzerman M, Flack MR, Jarratt M, Jones TM, Kircik L, Journal of drugs in dermatology : JDD, 2012

Human metapneumovirus: a ubiquitous and long-standing respiratory pathogen., Boivin G, Hamelin ME, The Pediatric infectious disease journal, 2005, 10.1097/01.inf.0000188158.27840.7c

Respiratory Syncytial Virus, Human Metapneumovirus, and the Parainfluenza Viruses, , Manual of Molecular and Clinical Laboratory Immunology, 7th Edition, 2006, 10.1128/9781555815905.ch79

Innate immune response during herpes simplex virus encephalitis and development of immunomodulatory strategies, Boivin, G., Piret, J., Reviews in Medical Virology, 2015, 10.1002/rmv.1848

Antibiotic use in children is not influenced by the result of rapid antigen detection test for the respiratory syncytial virus., Déry P, Boivin G, De Serres G, Côté S, Gilca R, Thibeault R, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2007, 10.1016/j.jcv.2007.04.013

Antiviral Drug Resistance in Herpesviruses, Guy Boivin, Emilien Drouot, Jocelyne Piret, Handbook of Antimicrobial Resistance, 2017, 10.1007/978-1-4939-0694-9_7

Virus-like particle vaccine induces cross-protection against human metapneumovirus infections in mice., Cosset FL, Boivin G, Lavillette D, Szécsi J, Granier C, Hamelin MÈ, Aerts L, Lévy C, Vaccine, 2013, 10.1016/j.vaccine.2013.03.051

97. Competition Experiments for the Baloxavir-Resistant I38T Influenza A Mutant, Guy Boivin, Yacine Abed, Mariana Baz, Julie Carbonneau, Zeineb Mhamdi, Liva Checkmahomed, Open Forum Infectious Diseases, 2019, 10.1093/ofid/ofz359.021

Single Dose IV Peramivir Treatment in Pediatric Influenza: Lack of Development of Influenza Virus Variants with Reduced Susceptibility to Peramivir, Guy Boivin, Phil Collis, Ray Taylor, Katyna Borroto-Esoda, Smail Kulenovic, Saskia Smits, Rienk Jeeninga, Julie Carbonneau, Yacine Abed, Marie-Ève Hamelin, Open Forum Infectious Diseases, 2017, 10.1093/ofid/ofx163.1353

Differential impact of various substitutions at codon 715 in region II of HSV-1 and HCMV DNA polymerases, Boivin, G., Shi, R., Piret, J., Goyette, N., Zhu, X., Zarrouk, K., Antiviral Research, 2021, 10.1016/j.antiviral.2021.105046

Predictive risk factors for hospitalization and response to colchicine in patients with COVID-19, Guy Boivin, Marie-Pierre Dubé, Nadia Bouabdallaoui, Marie-Claude Guertin, Mariève Cossette, Jean-Claude Tardif, International Journal of Infectious Diseases, 2022, 10.1016/j.ijid.2022.01.020

Peramivir susceptibilities of recombinant influenza A and B variants selected with various neuraminidase inhibitors, Boivin, G., Abed, Y., Carbonneau, J., Tu, V., Fage, C., Antiviral Therapy, 2017, 10.3851/IMP3158

A protectin DX (PDX) analog with in vitro activity against influenza A(H1N1) viruses, Guy Boivin, Yacine Abed, Donald Poirier, André Marette, Jean‐Yves Sancéau, René Maltais, Nathalie Goyette, Mathilde Hénaut, Nicolas Fortin, Journal of Medical Virology, 2024, 10.1002/jmv.29484

1468. PCV13 Serotype Trends Over Time in Pneumococcal Community Acquired Pneumonia: Which Method(s) Work Best?, Shelly A McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Makeda Semret, Allison McGeer, Anne Mccarthy, Mark Loeb, Jennie Johnstone, Karen Green, William R Bowie, Guy Boivin, Melissa K Andrew, Irene Martin, Todd Hatchette, Ardith Ambrose, Donna Mackinnon-Cameron, Lingyun Ye, May Elsherif, Jason Leblanc, Open Forum Infectious Diseases, 2018, 10.1093/ofid/ofy210.1298

Disseminated herpes simplex virus type 1 primary infection in a healthy individual., Goyette N, Malette B, Boivin G, The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2009, 10.1155/2009/482407

Immunogenicity is not improved by increased antigen dose or booster dosing of seasonal influenza vaccine in a randomized trial of HIV infected adults., CIHR Canadian HIV Trials Network Influenza Vaccine Research Group, Walmsley S, Halperin S, Singer J, Zubyk W, Shafran S, Haase D, Boivin G, Conway B, Klein M, Thorne A, Cooper C, PloS one, 2011, 10.1371/journal.pone.0017758

New Saffold cardioviruses in 3 children, Canada., Boivin G, Abed Y, Emerging infectious diseases, 2008, 10.3201/eid1405.071675

Seroprevalence of anti-SARS-CoV-2 antibodies among school and daycare children and personnel: Protocol for a cohort study in Montreal, Canada, Quach C, Savard-Lamothe A, Pierce L, Apostolatos A, Saucier A, Hamelin M, Fortin G, Papenburg J, Charland K, Zahreddine M, Bourque N, McKinnon B, Zinszer K, 2021, 10.1101/2021.04.14.21255499

Immunogenicity and tolerability of an inactivated and adjuvanted pandemic H1N1 influenza vaccine, in HIV-1-infected patients., Boivin G, Sékaly RP, Trautman L, Sampalis J, Baz M, Cote S, Cyr L, Sylla M, Toma E, Fortin C, Rouleau D, Tremblay CL, Vaccine, 2010, 10.1016/j.vaccine.2010.12.023

Human parechovirus causes encephalitis with white matter injury in neonates., de Vries LS, Boivin G, van Loon AM, Hellmann J, Hahn CD, Groenendaal F, Verboon-Maciolek MA, Annals of neurology, 2008, 10.1002/ana.21445

Herpes Simplex Virus 1 Infection Does Not Increase Amyloid-β Pathology in APP/PS1 Mice, Guy Boivin, Serge Rivest, Paul Préfontaine, Olus Uyar, Vincent Pons, Chantal Rhéaume, Jocelyne Piret, Lina Lapeyre, Journal of Alzheimer's Disease, 2024, 10.3233/jad-230746

2715. Pneumococcal Community-Acquired Pneumonia Attributed to PCV13 Serotypes in Hospitalized Adults: Comparison of the 50–64 and 65+ Age Groups, Shelly McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Makeda Semret, Allison McGeer, Anne McCarthy, Mark Loeb, Jennie Johnstone, Karen Green, William Bowie, Guy Boivin, Melissa K Andrew, Walter Demczuk, Irene Martin, Hayley D Gillis, Amanda L S Lang, Todd F Hatchette, Ardith Ambrose, Donna MacKinnon-Cameron, Lingyun Ye, May ElSherif, Jason J LeBlanc, Open Forum Infectious Diseases, 2019, 10.1093/ofid/ofz360.2392

Antiviral Drug Resistance in Herpesviruses, Guy Boivin, Emilien Drouot, Jocelyne Piret, Handbook of Antimicrobial Resistance, 2014, 10.1007/978-1-4939-0667-3_7-1

Cross-lineage influenza B and heterologous influenza A antibody responses in vaccinated mice: immunologic interactions and B/Yamagata dominance., Boivin G, Bouhy X, Rhéaume C, Gardy JL, De Serres G, Janjua NZ, Hamelin ME, Skowronski DM, PloS one, 2012, 10.1371/journal.pone.0038929

Role of picornaviruses in flu-like illnesses of adults enrolled in an oseltamivir treatment study who had no evidence of influenza virus infection., Ward P, Groen J, Jackson HC, Gaudreau A, Osterhaus AD, Boivin G, Journal of clinical microbiology, 2002, 10.1128/jcm.40.2.330-334.2002

Resource utilization and cost of influenza requiring hospitalization in Canadian adults: A study from the serious outcomes surveillance network of the Canadian Immunization Research Network, McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Stiver, G., Smyth, D., Smith, S., Semret, M., Sharma, R., Richardson, D., Powis, J., Poirier, A., McGeer, A., McElhaney, J., McCarthy, A., MacKinnon-Cameron, D., Loeb, M., Leblanc, J., Katz, K., Johnstone, J., Green, K., ElSherif, M., Bowie, W., Boivin, G., Hatchette, T., Andrew, M.K., Ambrose, A., Goeree, R., Thommes, E., Hux, M., Noorduyn, S.G., Ye, L., Ng, C., Influenza and other Respiratory Viruses, 2018, 10.1111/irv.12521

Assessing the in vitro fitness of an oseltamivir-resistant seasonal A/H1N1 influenza strain using a mathematical model., Boivin G, Beauchemin CA, Bouhy X, Abed Y, Liao LE, Simon P, Holder BP, PloS one, 2011, 10.1371/journal.pone.0014767

Characterization of multiple cytomegalovirus drug resistance mutations detected in a hematopoietic stem cell transplant recipient by recombinant phenotyping, Boivin, G., Lebel, M.H., Piret, J., Drouot, E., Journal of Clinical Microbiology, 2014, 10.1128/JCM.02205-14

Human metapneumovirus infections in hospitalized children., Déry P, Bergeron MG, Rochette L, Abed Y, Gilca R, Côté S, De Serres G, Boivin G, Emerging infectious diseases, 2003, 10.3201/eid0906.030017

Interim estimates of 2013/14 influenza clinical severity and vaccine effectiveness in the prevention of laboratory-confirmed influenza-related hospitalisation, Canada, February 2014, McGeer, A., Ye, L., Webster, D., Valiquette, L., Trottier, S., Stiver, G., Smyth, D., Smith, S., Semret, M., Richardson, D., Powis, J., Poirier, M., McCarthy, A.E., MacKinnon-Cameron, D., McElhaney, J., Loeb, M., Light, B., Lagacã-Wiens, P., Langley, J.M., Katz, K., Ibarguchi, B., Halperin, S., Haguinet, F., Green, K., ElSherif, M., Diaz-Mitoma, F., Bowie, W.R., Boivin, G., Ambrose, A., Leblanc, J., Hatchette, T.F., Andrew, M., Shinde, V., McNeil, S.A., Eurosurveillance, 2014, 10.2807/1560-7917.ES2014.19.9.20729

Host and viral factors affecting clinical performance of a rapid diagnostic test for respiratory syncytial virus in hospitalized children., Boivin G, De Serres G, Buckeridge DL, Papenburg J, The Journal of pediatrics, 2013, 10.1016/j.jpeds.2013.03.067

The E119D neuraminidase mutation identified in a multidrug-resistant influenza A(H1N1)pdm09 isolate severely alters viral fitness in vitro and in animal models, Boivin, G., Kaiser, L., Mallett, C., Beaulieu, E., Joly, M.-H., Dubé, K., Fage, C., Retamal, M., Pizzorno, A., Rhéaume, C., L'Huillier, A.G., Bouhy, X., Abed, Y., Antiviral Research, 2016, 10.1016/j.antiviral.2016.05.006

In vitro activity of letermovir against human cytomegalovirus isolates with different drug susceptibility phenotypes, Guy Boivin, Nathalie Goyette, Jocelyne Piret, Antiviral Research, 2022, 10.1016/j.antiviral.2022.105328

Herpesvirus Resistance to Antiviral Drugs, Guy Boivin, Jocelyne Piret, Antimicrobial Drug Resistance, 2017, 10.1007/978-3-319-47266-9_24

Fluorescent polymeric transducer for the rapid, simple, and specific detection of nucleic acids at the zeptomole level., Leclerc M, Boudreau D, Bergeron MG, Boivin G, Boissinot M, Corbeil G, Brunette M, Lévesque I, Ho HA, Dubus S, Doré K, Journal of the American Chemical Society, 2004, 10.1021/ja038900d

The Changing Landscape of Respiratory Viruses Contributing to Hospitalizations in Quebec, Canada: Results From an Active Hospital-Based Surveillance Study (Preprint), Jeannot Dumaresq, Hugues Charest, Guy Boivin, Charles Frenette, Radhouene Doggui, Sara Carazo, Rachid Amini, Rodica Gilca, 2022, 10.2196/preprints.40792

Epitope mapping of the 2009 pandemic and the A/brisbane/59/2007 seasonal (H1N1) influenza virus haemagglutinins using mabs and escape mutants, Boivin, G., Corbeil, J., Abed, Y., Retamal, M., Journal of General Virology, 2014, 10.1099/vir.0.067819-0

Influenza virus activates human immunodeficiency virus type-1 gene expression in human CD4-expressing T cells through an NF-kappaB-dependent pathway., Tremblay MJ, Boivin G, Barbeau B, Bergeron M, Sun J, Clinical immunology (Orlando, Fla.), 2005, 10.1016/j.clim.2004.10.002

Evaluation of the AMPLICOR cytomegalovirus test with specimens from human immunodeficiency virus-infected subjects., Bergeron MG, Sun R, Tevere VJ, Lalonde R, Murray G, Toma E, Handfield J, Boivin G, Journal of clinical microbiology, 1998, 10.1128/jcm.36.9.2509-2513.1998

Identification and evaluation of a highly effective fusion inhibitor for human metapneumovirus., Boivin G, Prince GA, Hamelin ME, Deffrasnes C, Antimicrobial agents and chemotherapy, 2007, 10.1128/aac.00793-07

In-vivo and human evidence for potential efficacy of therapeutic polyclonal RSV neutralizing antibodies for palivizumab-resistant RSV infections, John P. DeVincenzo, Bindiya Bagga, Ann R. Falsey, Brian E. Gilbert, Guy Boivin, Jesse Papenburg, James Mond, Kacy Ramirez, Virology, 2023, 10.1016/j.virol.2023.07.007

Whole-genome characterization and genotyping of global WU polyomavirus strains., Sloots TP, Lindau C, Leach AJ, Gilroy NM, Ferguson PE, Chung JY, Cheng AC, Boivin G, Binks M, Allander T, Abed Y, Whiley DW, Rockett R, Bialasiewicz S, Journal of virology, 2010, 10.1128/jvi.02658-09

The impact of prior season vaccination on subsequent influenza vaccine effectiveness to prevent influenza-related hospitalizations over 4 influenza seasons in Canada, McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Smyth, D., Shinde, V., Sharma, R., Semret, M., Richardson, D., Powis, J., McGeer, A., McElhaney, J.E., McCarthy, A., Mackinnon-Cameron, D., Loeb, M., Leblanc, J., Katz, K., Haguinet, F., Green, K., Elsherif, M., Dos Santos, G., Bowie, W., Boivin, G., Ambrose, A., Hatchette, T.F., Ye, L., Andrew, M.K., Nichols, M.K., Clinical Infectious Diseases, 2019, 10.1093/cid/ciy1009

The possibility of spreading herpes simplex virus type 1 via food handling and sharing, Julie Jean, Guy Boivin, Valérie Goulet-Beaulieu, Eric Jubinville, Teresa Paniconi, Marianne Levasseur, Gabrielle Pageau, Journal of Applied Microbiology, 2023, 10.1093/jambio/lxad224

Decrease in PCV13 Serotypes in Adults Hospitalized with Pneumococcal Pneumonia Over Time: Evidence of Herd Immunity Effects from Childhood Vaccination, Shelly McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Makeda Semret, Allison Mcgeer, Anne Mccarthy, Mark Loeb, Jennie Johnstone, Karen Green, William R Bowie, Guy Boivin, Melissa K Andrew, Ardith Ambrose, Irene Martin, Haley Gillis, Amanda Lang, Todd Hatchette, Donna Mackinnon-Cameron, Lingyun Ye, May Elsherif, Jason Leblanc, Open Forum Infectious Diseases, 2017, 10.1093/ofid/ofx163.1485

Case study: rapid emergence of a cytomegalovirus UL97 mutant in a heart-transplant recipient on pre-emptive ganciclovir therapy., Boivin G, LeBlanc MH, Gilbert C, Herpes : the journal of the IHMF, 2001

Herpes simplex encephalitis in adult patients with MASP-2 deficiency, Bochud, P.-Y., Boivin, G., Rivolta, C., Fellmann, F., Erard, V., Bihl, T., Meylan, P., Menasria, R., Michielin, O., Zoete, V., Collinet, E., Quinodoz, M., Piret, J., Bibert, S., PLoS Pathogens, 2019, 10.1371/journal.ppat.1008168

Impact of mutations at residue I223 of the neuraminidase protein on the resistance profile, replication level, and virulence of the 2009 pandemic influenza virus, Boivin, G., Russell, R., Mallett, C., Beaulieu, É., Bouhy, X., Abed, Y., Pizzorno, A., Antimicrobial Agents and Chemotherapy, 2012, 10.1128/AAC.05994-11

2714. Streptococcus pneumoniae Nasopharyngeal Carriage in Canadian Adults Hospitalized with Community-Acquired Pneumonia from 2010 to 2017, Shelly McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Makeda Semret, Allison McGeer, Anne McCarthy, Mark Loeb, Jennie Johnstone, Karen Green, William Bowie, Guy Boivin, Melissa K Andrew, Walter Demczuk, Irene Martin, Todd F Hatchette, Ardith Ambrose, Donna MacKinnon-Cameron, Lingyun Ye, Hayley D Gillis, Amanda L S Lang, May ElSherif, Jason J LeBlanc, Open Forum Infectious Diseases, 2019, 10.1093/ofid/ofz360.2391

Duration of isolation and contagiousness in coronavirus disease 2019 (COVID-19) patients receiving tocilizumab and dexamethasone: A case series, Marie-Claude Roy, Marie-Ève Hamelin, Julie Carbonneau, Julie Bestman-Smith, Annie Ruest, Vilayvong Loungnarath, Guy Boivin, Florence Côté, Infection Control & Hospital Epidemiology, 2023, 10.1017/ice.2022.14

Diagnosis of herpesvirus infections of the central nervous system., Boivin G, Herpes : the journal of the IHMF, 2004

A Cluster of Three Cases of Hantavirus Pulmonary Syndrome among Canadian Military Personnel., Loo VG, Boivin G, Vinh DC, Bestman-Smith J, Beaudoin MC, Longtin J, Nguyen TT, Parkes LO, The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2016, 10.1155/2016/2757969

Human metapneumovirus infection in adults with community-acquired pneumonia and exacerbation of chronic obstructive pulmonary disease., Boivin G, DeSerres G, Gilca R, Weiss K, Bourbeau J, Lampron N, Laforge J, Côté S, Hamelin ME, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2005, 10.1086/431981

Human metapneumovirus genetic variability, South Africa., Madhi SA, Klugman KP, Boivin G, van Niekerk N, Abed Y, Ludewick HP, Emerging infectious diseases, 2005, 10.3201/eid1107.050050

Cytomegalovirus (CMV) virus load kinetics to predict recurrent disease in solid-organ transplant patients with CMV disease., Caliendo AM, Boivin G, Kumar D, Humar A, The Journal of infectious diseases, 2002, 10.1086/342601

Influence of letermovir treatment on gut inflammation in people living with HIV on antiretroviral therapy: protocol of the open-label controlled randomised CIAO study, Jean-Pierre Routy, Guy Boivin, Cécile Tremblay, Rejean Thomas, Cecilia T. Costiniuk, Nadine Kronfli, Alexandra de Pokomandy, Bertrand Lebouché, Marina Klein, Nicolas Chomont, Talat Bessissow, Peter L. Lakatos, Simeng Bu, Carolina A. Berini, Stéphane Isnard, Léna Royston, BMJ Open, 2023, 10.1136/bmjopen-2022-067640

WU polyomavirus in children, Canada., Boivin G, Wang D, Abed Y, Emerging infectious diseases, 2007, 10.3201/eid1312.070909

A case of ganciclovir-resistant cytomegalovirus (CMV) retinitis in a patient with AIDS: longitudinal molecular analysis of the CMV viral load and viral mutations in blood compartments., Bergeron MG, Morissette M, Handfield J, Goyette N, Gilbert C, Boivin G, AIDS (London, England), 1997, 10.1097/00002030-199707000-00005

Drug susceptibility and replicative capacity of multidrug-resistant recombinant human cytomegalovirus harboring mutations in UL56 and UL54 genes, Boivin, G., Goyette, N., Piret, J., Antimicrobial Agents and Chemotherapy, 2017, 10.1128/AAC.01044-17

Cytomegalovirus quantification in plasma with Abbott RealTime CMV and Roche Cobas Amplicor CMV assays, Longtin, J., Boivin, G., Deschênes, L., Rodrigue, M.-A., Tremblay, M.-A., Journal of Virological Methods, 2015, 10.1016/j.jviromet.2015.08.010

Therapeutic activity of intramuscular peramivir in mice infected with a recombinant influenza A/WSN/33 (H1N1) virus containing the H275Y neuraminidase mutation., Boivin G, Pizzorno A, Abed Y, Antimicrobial agents and chemotherapy, 2012, 10.1128/aac.00753-12

Quantitation of cytomegalovirus: methodologic aspects and clinical applications., Boivin G, Boeckh M, Clinical microbiology reviews, 1998, 10.1128/cmr.11.3.533

Seroprevalence of anti-SARS-CoV-2 antibodies among school and daycare children and personnel: protocol for a cohort study in Montreal, Canada, Caroline Quach, Gaston De Serres, Guy Boivin, Isabelle Laurin, Patricia Conrod, Nancy Haley, Julie Carbonneau, Ashley Savard-Lamothe, Laura Pierce, Alex Apostolatos, Marie-Ève Hamelin, Adrien Saucier, Geneviève Fortin, Jesse Papenburg, Katia Charland, Monica Zahreddine, Noémie Bourque, Britt McKinnon, Kate Zinszer, BMJ Open, 2021, 10.1136/bmjopen-2021-053245

Impact of temperature on the affinity of SARS-CoV-2 Spike for ACE2, Andrés Finzi, Arne Schön, Cameron F. Abrams, Guy Boivin, Emmanuelle Brochiero, Marzena Pazgier, Walther Mothes, Michel Roger, Hugues Charest, Sandrine Moreira, Anik Privé, Guillaume Goyette, Shang Yu Gong, Mehdi Benlarbi, Alexandra Tauzin, Natasha Gupta Vergara, Damien Adam, Sai Priya Anand, Clément Fage, Shilei Ding, Romain Gasser, Jonathan Richard, Jérémie Prévost, 1911, 10.1101/2021.07.09.451812

Compartmentalization of a Multidrug-Resistant Cytomegalovirus UL54 Mutant in a Stem Cell Transplant Recipient with Encephalitis, Boivin, G., Shi, R., Alain, S., Goyette, N., Kaiser, L., Masouridi-Levrat, S., Giannotti, F., Hantz, S., Pham, V.D., Schibler, M., Piret, J., Journal of Infectious Diseases, 2019, 10.1093/infdis/jiz298

Recent developments with live-attenuated recombinant paramyxovirus vaccines., Boivin G, Rosa-Calatrava M, Lina B, Le Bayon JC, Reviews in medical virology, 2012, 10.1002/rmv.1717

Household transmission of the 2009 pandemic A/H1N1 influenza virus: elevated laboratory‐confirmed secondary attack rates and evidence of asymptomatic infections., Boivin G, De Serres G, Charest H, Roger M, Skowronski D, Hardy I, Rouleau I, Ouakki M, Carbonneau J, Rhéaume C, Hamelin MÈ, Baz M, Papenburg J, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2010, 10.1086/656582

Evaluation of recombinant 2009 pandemic influenza A (H1N1) viruses harboring zanamivir resistance mutations in mice and ferrets., Boivin G, Bouhy X, Rhéaume C, Abed Y, Pizzorno A, Antimicrobial agents and chemotherapy, 2013, 10.1128/aac.02269-12

The Val430Ile neuraminidase (NA) substitution, identified in influenza B virus isolates, impacts the catalytic 116Arg residue causing reduced susceptibility to NA inhibitors, Boivin, G., Lague, P., Carbonneau, J., Begin, G., Checkmahomed, L., Fage, C., Abed, Y., Antiviral Research, 2019, 10.1016/j.antiviral.2019.104561

Impact of potential permissive neuraminidase mutations on viral fitness of the H275Y oseltamivir-resistant influenza A(H1N1)pdm09 virus in vitro, in mice and in ferrets, Boivin, G., Rhéaume, C., Bouhy, X., Pizzorno, A., Abed, Y., Journal of Virology, 2014, 10.1128/JVI.02681-13

A novel neuraminidase deletion mutation conferring resistance to oseltamivir in clinical influenza A/H3N2 virus., Boivin G, Baz M, Abed Y, The Journal of infectious diseases, 2009, 10.1086/595736

Human parainfluenza type 4 infections, Canada., Boivin G, Bergeron MG, Moisan D, Leblanc E, Dionne N, Vachon ML, Emerging infectious diseases, 2006, 10.3201/eid1211.060196

The quest for a nanoparticle-based vaccine inducing broad protection to influenza viruses, Leclerc, D., Savard, P., Boivin, G., Russel, A., Garneau, C., Carignan, D., Laliberté-Gagné, M.-È., Baz, M., Bolduc, M., Nanomedicine: Nanotechnology, Biology, and Medicine, 2018, 10.1016/j.nano.2018.08.010

Both IRF3 and especially IRF7 play a key role to orchestrate an effective cerebral inflammatory response in a mouse model of herpes simplex virus encephalitis, Boivin, G., Gosselin, J., Piret, J., Lebel, M., Rhéaume, C., Canivet, C., Journal of NeuroVirology, 2018, 10.1007/s13365-018-0666-9

Comparative evaluation of three serological methods for detection of human herpesvirus 8-specific antibodies in Canadian allogeneic stem cell transplant recipients., Boivin G, Roy J, Abed Y, Sergerie Y, Journal of clinical microbiology, 2004, 10.1128/jcm.42.6.2663-2667.2004

E119D Neuraminidase Mutation Conferring Pan-Resistance to Neuraminidase Inhibitors in an A(H1N1)pdm09 Isolate from a Stem-Cell Transplant Recipient, Kaiser, L., Boivin, G., Boquete-Suter, P., Zdobnov, E., Van Delden, C., Chalandon, Y., Simon, A., Schibler, M., Bouhy, X., Thomas, Y., Cordey, S., Petty, T.J., Abed, Y., L'Huillier, A.G., Journal of Infectious Diseases, 2015, 10.1093/infdis/jiv288

Omicron incidence and seroprevalence among children in Montreal, Canada, in early 2023: final results from the longitudinal EnCORE serology study, Kate Zinszer, Caroline Quach, Guy Boivin, Jesse Papenburg, Gaston De Serres, Cat Tuong Nguyen, Julie Carbonneau, Margot Barbosa Da Torre, Marie-Ève Hamelin, Adrien Saucier, Laura Pierce, Katia Charland, Epidemiology and Infection, 2024, 10.1017/s0950268824000797

Comparison of risk factors for human metapneumovirus and respiratory syncytial virus disease severity in young children., Boivin G, De Serres G, Frenette L, Caouette G, Corbeil J, Robitaille L, Raymond F, Ouakki M, Carbonneau J, Ouhoummane N, Hamelin MÈ, Papenburg J, The Journal of infectious diseases, 2012, 10.1093/infdis/jis333

Amphipathic DNA polymers are candidate vaginal microbicides and block herpes simplex virus binding, entry and viral gene expression., Herold BC, Vaillant A, Boivin G, Juteau JM, Goyette N, Keller MJ, Shende V, Cheshenko N, Guzman EM, Antiviral therapy, 2007

Evaluation of serological diagnostic methods for the 2009 pandemic influenza A (H1N1) virus., Boivin G, De Serres G, Rouleau I, Ouakki M, Carbonneau J, Rhéaume C, Hamelin MÈ, Baz M, Papenburg J, Clinical and vaccine immunology : CVI, 2011, 10.1128/cvi.00449-10

Oseltamivir Reduces 30-Day Mortality in Older Adults With Influenza: A Pooled Analysis From the 2012–2019 Serious Outcomes Surveillance Network of the Canadian Immunization Research Network, Shelly A McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Grant Stiver, Daniel Smyth, Stephanie Smith, Makeda Semret, David Richardson, Jeff Powis, Andre Poirier, Allison McGeer, Anne McCarthy, Mark Loeb, Phillipe Lagacé-Wiens, Kevin Katz, Jennie Johnstone, William Bowie, Guy Boivin, Ardith Ambrose, Jason J LeBlanc, Todd F Hatchette, May ElSherif, Lingyun Ye, Michaela K Nichols, Zachary Shaffelburg, Melissa K Andrew, Henrique Pott, Open Forum Infectious Diseases, 2025, 10.1093/ofid/ofaf058

Influenza vaccine oculorespiratory syndrome incidence is reduced in HIV., Canadian Institutes of Health Research-Canadian HIV Trials Network (CTN) Influenza Vaccine Research Group, Thorne A, Cooper C, Vaccine, 2011, 10.1016/j.vaccine.2011.08.066

Standardization of Hemagglutination Inhibition Assay for Influenza Serology Allows for High Reproducibility between Laboratories, Hatchette, T.F., LeBlanc, J.J., McNeil, S.A., Warhuus, M., Li, Y., Boivin, G., Tang, P., Brewer, A., Ward, B.J., Zacour, M., Clinical and Vaccine Immunology, 2016, 10.1128/CVI.00613-15

Enhanced lung disease and Th2 response following human metapneumovirus infection in mice immunized with the inactivated virus., Boivin G, Sackett MK, Couture C, Hamelin MÈ, The Journal of general virology, 2007, 10.1099/vir.0.83250-0

The Changing Landscape of Respiratory Viruses Contributing to Hospitalizations in Quebec, Canada: Results From an Active Hospital-Based Surveillance Study, Jeannot Dumaresq, Hugues Charest, Guy Boivin, Charles Frenette, Radhouene Doggui, Sara Carazo, Rachid Amini, Rodica Gilca, JMIR Public Health and Surveillance, 2024, 10.2196/40792

Phenotypic and genotypic characterization of acyclovir-resistant herpes simplex viruses from immunocompromised patients., Boivin G, Erice A, Balfour HH, Hill E, Gaudreau A, The Journal of infectious diseases, 1998, 10.1086/515626

New reporter cell line to evaluate the sequential emergence of multiple human cytomegalovirus mutations during in vitro drug exposure., Boivin G, Gilbert C, Antimicrobial agents and chemotherapy, 2005, 10.1128/aac.49.12.4860-4866.2005

Infection‐induced seroconversion and seroprevalence of SARS‐CoV‐2 among a cohort of children and youth in Montreal, Canada, Caroline Quach, Guy Boivin, Jesse Papenburg, Gaston De Serres, Cat Tuong Nguyen, Julie Carbonneau, Margot Barbosa Da Torre, Marie‐Ève Hamelin, Adrien Saucier, Laura Pierce, Katia Charland, Kate Zinszer, Influenza and Other Respiratory Viruses, 2023, 10.1111/irv.13186

Evaluation of anticoagulant agents for the treatment of human metapneumovirus infection in mice, Boivin, G., Hamelin, M.-È., Venable, M.-C., Checkmahomed, L., Couture, C., Jandrot-Perrus, M., Lê, B.V., Journal of General Virology, 2018, 10.1099/jgv.0.001135

Susceptibility of recent Canadian influenza A and B virus isolates to different neuraminidase inhibitors., Goyette N, Boivin G, Antiviral research, 2002, 10.1016/s0166-3542(01)00219-4

Recalibrated estimates of non-bacteremic and bacteremic pneumococcal community acquired pneumonia in hospitalized Canadian adults from 2010 to 2017 with addition of an extended spectrum serotype-specific urine antigen detection assay, Shelly A. McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Makeda Semret, Allison McGeer, Anne E. McCarthy, Mark Loeb, Jennie Johnstone, Karen Green, William Bowie, Guy Boivin, Melissa K. Andrew, Walter H.B. Demczuk, Irene Martin, Hayley D. Gillis, Amanda L.S. Lang, Todd F. Hatchette, Ardith Ambrose, Donna MacKinnon-Cameron, Lingyun Ye, May ElSherif, Jason J. LeBlanc, Vaccine, 2022, 10.1016/j.vaccine.2022.02.081

Lack of emergence of cytomegalovirus UL97 mutations conferring ganciclovir (GCV) resistance following preemptive GCV therapy in allogeneic stem cell transplant recipients., Boivin G, Demers C, Beliveau C, Delage R, Belanger R, Roy J, Gilbert C, Antimicrobial agents and chemotherapy, 2001, 10.1128/aac.45.12.3669-3671.2001

Evaluation of the human herpesvirus 8 DNA load in blood and Kaposi's sarcoma skin lesions from AIDS patients on highly active antiretroviral therapy., Routy JP, Gaudreau A, Boivin G, AIDS (London, England), 2000, 10.1097/00002030-200009080-00004

Molecular evolution of respiratory syncytial virus fusion gene, Canada, 2006-2010., Boivin G, De Serres G, Bergeron MG, Corbeil J, Paes BA, Déry P, Ohoumanne N, Bouhy X, Isabel S, Hamelin MÈ, Carbonneau J, Papenburg J, Emerging infectious diseases, 2012, 10.3201/eid1801.110515

The combination of valacyclovir with an anti-TNF alpha antibody increases survival rate compared to antiviral therapy alone in a murine model of herpes simplex virus encephalitis, Boivin, G., Rivest, S., Piret, J., Menasria, R., Boivin, N., Antiviral Research, 2013, 10.1016/j.antiviral.2013.10.007

Pathogenesis of human metapneumovirus lung infection in BALB/c mice and cotton rats., Boivin G, Prince GA, Blanco JC, Boukhvalova M, Cragin RP, Kuhn KH, Yim K, Hamelin ME, Journal of virology, 2005, 10.1128/jvi.79.14.8894-8903.2005

Analysis of replication kinetics of the human metapneumovirus in different cell lines by real-time PCR., Boivin G, Côté S, Deffrasnes C, Journal of clinical microbiology, 2005, 10.1128/jcm.43.1.488-490.2005

Novel antiviral compounds and combination therapy for influenza viruses,Nouveaux composés antiviraux et thérapie combinée contre les virus influenza, Lina, B., Rosa-Calatrava, M., Boivin, G., Virologie, 2019, 10.1684/vir.2019.0803

Treatment of respiratory virus infections., Boivin G, Abed Y, Antiviral research, 2006, 10.1016/j.antiviral.2006.01.006

RSV and HMPV Infections in 3D Tissue Cultures: Mechanisms Involved in Virus-Host and Virus-Virus Interactions, Essaidi-Laziosi, M., Tapparel, C., Kaiser, L., Constant, S., Huang, S., Boivin, G., Geiser, J., Viruses, 2021, 10.3390/v13010139

Colchicine for community-treated patients with COVID-19 (COLCORONA): a phase 3, randomised, double-blinded, adaptive, placebo-controlled, multicentre trial., COLCORONA Investigators, Denault A, Dupuis J, Audet S, Verret L, da Luz P, Lopez-Sendon J, Pillinger MH, Shah B, Gaudet D, L'Allier PL, Bouabdallaoui N, Tardif JC, The Lancet. Respiratory medicine, 2021, 10.1016/s2213-2600(21)00222-8

Reply to "Calibration technologies for correct determination of Epstein-Barr Virus, human herpesvirus 6 (HHV-6), and HHV-8 antiviral drug susceptibilities by use of real-time-PCR-based assays"., Boivin G, Goyette N, Piret J, Bounaadja L, Journal of clinical microbiology, 2013, 10.1128/jcm.00545-13

Thymidine kinase mutations conferring acyclovir resistance in herpes simplex type 1 recombinant viruses., Boivin G, Sergerie Y, Antimicrobial agents and chemotherapy, 2006, 10.1128/aac.00889-06

Ganciclovir susceptibilities of cytomegalovirus (CMV) isolates from solid organ transplant recipients with CMV viremia after antiviral prophylaxis., Balfour HH, Dunn DL, Crane DD, Erice A, Boivin G, The Journal of infectious diseases, 1993, 10.1093/infdis/168.2.332

A Reverse Genetics Study of Resistance to Neuraminidase Inhibitors in An Influenza A/H1N1 Virus, Guy Boivin, Nathalie Goyette, Yacine Abed, Antiviral Therapy, 2004, 10.1177/135965350400900404

Human metapneumovirus-associated lower respiratory tract infections among hospitalized human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants., Boivin G, Klugman KP, Abed Y, Ludewick H, Madhi SA, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2003, 10.1086/379771

Zika virus and impact on male fertility, Guy Boivin, Jocelyne Piret, Zika Virus Biology, Transmission, and Pathology, 2021, 10.1016/b978-0-12-820268-5.00026-2

Ozone inactivation of airborne influenza and lack of resistance of respiratory syncytial virus to aerosolization and sampling processes, Caroline Duchaine, Nathalie Grandvaux, Guy Boivin, Espérance Mukawera, Christophe Tremblay, Nathalie Turgeon, Jonathan M. Vyskocil, Étienne Racine, Marie-Eve Dubuis, PLOS ONE, 2021, 10.1371/journal.pone.0253022

Phenotypic and genotypic characterization of acyclovir-resistant varicella-zoster viruses isolated from persons with AIDS., Balfour HH, Biron KK, Talarico CL, Pedneault L, Edelman CK, Boivin G, The Journal of infectious diseases, 1994, 10.1093/infdis/170.1.68

The recruitment of peripheral blood leukocytes to the brain is delayed in susceptible BALB/c compared to resistant C57BL/6 mice during herpes simplex virus encephalitis, Boivin, G., Piret, J., Rhéaume, C., Uyar, O., Canivet, C., Journal of NeuroVirology, 2019, 10.1007/s13365-019-00730-5

Novel method based on "en passant" mutagenesis coupled with a gaussia luciferase reporter assay for studying the combined effects of human cytomegalovirus mutations., Boivin G, Piret J, Drouot E, Journal of clinical microbiology, 2013, 10.1128/jcm.01275-13

In vitro fitness of SARS-CoV-2 variants as assessed by competition experiments followed by ddRT-PCR and whole genome sequencing, Guy Boivin, Ines Levade, Chantal Rhéaume, Julie Carbonneau, Mathilde Hénaut, Journal of Clinical Virology, 2023, 10.1016/j.jcv.2023.105517

Modulation of TLR9 response in a mouse model of herpes simplex virus encephalitis., Boivin G, Piret J, Menasria R, Boivin N, Antiviral research, 2012, 10.1016/j.antiviral.2012.09.022

Early effects of ganciclovir therapy on the quantity of cytomegalovirus DNA in leukocytes of immunocompromised patients., Jordan MC, Germain M, Kringstad BA, Quirk MR, Boivin G, Antimicrobial agents and chemotherapy, 1997, 10.1128/aac.41.4.860

The changing landscape of respiratory viruses contributing to respiratory hospitalisations: results from a hospital-based surveillance in Quebec, Canada, 2012-13 to 2021-22, Jeannot Dumaresq, Hugues Charest, Guy Boivin, Charles Frenette, Sara Carazo, Rachid Amini, Rodica Gilca, 2022, 10.1101/2022.07.01.22277061

Impact of R152K and R368K neuraminidase catalytic substitutions on in vitro properties and virulence of recombinant A(H1N1)pdm09 viruses, Boivin, G., Fage, C., Baz, M., Abed, Y., Tu, V., Antiviral Research, 2018, 10.1016/j.antiviral.2018.04.009

Recombinant phenotyping of cytomegalovirus sequence variants detected after 200 or 100 days of valganciclovir prophylaxis., Elston R, Ives JA, Farhan M, Goyette N, Boivin G, Marousek G, Chou S, Transplantation, 2010, 10.1097/tp.0b013e3181fdd9d2

Drug resistance patterns of recombinant herpes simplex virus DNA polymerase mutants generated with a set of overlapping cosmids and plasmids., Boivin G, Bestman-Smith J, Journal of virology, 2003, 10.1128/jvi.77.14.7820-7829.2003

Impact of Neuraminidase Mutations Conferring Influenza Resistance to Neuraminidase Inhibitors in the N1 and N2 Genetic Backgrounds, Guy Boivin, Mariana Baz, Yacine Abed, Antiviral Therapy, 2006, 10.1177/135965350601100804

Quantitation of human cytomegalovirus glycoprotein H gene in cells using competitive PCR and a rapid fluorescence-based detection system., Jordan MC, St-Cyr SM, Quirk MR, Olson CA, Boivin G, Journal of virological methods, 1995, 10.1016/0166-0934(94)00128-4

Randomized controlled ferret study to assess the direct impact of 2008-09 trivalent inactivated influenza vaccine on A(H1N1)pdm09 disease risk, Boivin, G., Koopmans, M., Petric, M., Lavigne, S., Balshaw, R., De Bruin, E., Embury-Hyatt, C., Kobasa, D., Leung, A., Couture, C., Bouhy, X., Sabaiduc, S., Li, G., Janjua, N.Z., De Serres, G., Hamelin, M.-E., Skowronski, D.M., PLoS ONE, 2014, 10.1371/journal.pone.0086555

Prolonged excretion of amantadine-resistant influenza a virus quasi species after cessation of antiviral therapy in an immunocompromised patient., Bernatchez H, Goyette N, Boivin G, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2002, 10.1086/338870

Impact of Antivirals in the Prevention of Serious Outcomes Associated with Influenza in Hospitalized Canadian Adults: A Pooled Analysis from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN), Shelly McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Geoffrey Taylor, Daniel Smyth, Stephanie Smith, Vivek Shinde, Makeda Semret, David Richardson, Jeff Powis, Allison Mcgeer, Janet Mcelhaney, Anne Mccarthy, Donna Mackinnon-Cameron, Mark Loeb, Philippe Lagace-Wiens, Jason Leblanc, Joanne M Langley, Kevin Katz, Jennie Johnstone, Barbara Ibarguchi, Todd Hatchette, Scott A Halperin, Francois Haguinet, Karen Green, May Elsherif, Gael Dos Santos, Ayman Chit, William R Bowie, Guy Boivin, Ardith Ambrose, Melissa K Andrew, Lingyun Ye, Michaela Nichols, Zach Shaffelburg, Open Forum Infectious Diseases, 2017, 10.1093/ofid/ofx162.046

Human Metapneumovirus Genetic Variability, South Africa, Shabir A. Madhi, Keith P. Klugman, Guy Boivin, Nadia van Niekerk, Yacine Abed, Herbert P. Ludewick, Emerging Infectious Diseases, 2005, 10.3201/eid1107.050500

Rapid antiviral effect of inhaled zanamivir in the treatment of naturally occurring influenza in otherwise healthy adults., Trottier S, Wagner A, Aoki F, Hardy I, Goyette N, Boivin G, The Journal of infectious diseases, 2000, 10.1086/315392

Evaluation of pre- and post-fusion Human metapneumovirus F proteins as subunit vaccine candidates in mice, Boivin, G., Hamelin, M.-È., Guarné, A., Couture, C., Lavigne, S., Rhéaume, C., Venable, M.-C., Carbonneau, J., Shen, Y., Pilaev, M., Vaccine, 2020, 10.1016/j.vaccine.2020.01.047

In vitro properties and virulence of contemporary recombinant influenza b viruses harboring mutations of cross-resistance to neuraminidase inhibitors, Boivin, G., Venable, M.-C., Checkmahomed, L., Abed, Y., Fage, C., Viruses, 2019, 10.3390/v11010006

Frailty Hinders Recovery From Acute Respiratory Illness in Older Adults, Shelly McNeil, Lingyun Ye, Duncan Webster, Louis Valiquette, Sylvie Trottier, Geoffrey Taylor, Daniel Smyth, Stephanie Smith, Makeda Semret, David Richardson, Jeff Powis, Allison Mcgeer, Anne Mccarthy, Donna Mackinnon-Cameron, Mark Loeb, Philippe Lagace-Wiens, Jason Leblanc, Joanne M Langley, Kevin Katz, Jennie Johnstone, Todd Hatchette, Scott A Halperin, Karen Green, May Elsherif, William R Bowie, Guy Boivin, Ardith Ambrose, Janet McElhaney, Karen Black, Judith Godin, Caitlin Lees, Melissa K Andrew, Open Forum Infectious Diseases, 2017, 10.1093/ofid/ofx163.1500

Parenteral peramivir treatment for oseltamivir-resistant 2009 pandemic influenza a H1N1 viruses, Hernandez, J.E., Kodama, M., Yoshida, R., Boivin, G., Abed, Y., Journal of Infectious Diseases, 2011, 10.1093/infdis/jir610

Cell culture systems to study human herpesvirus 6A/B chromosomal integration, Flamand, L., Kaufer, B.B., Boivin, G., Carbonneau, J., Mori, Y., Jerome, K.R., Hall-Sedlak, R., Collin, V., Gilbert-Girard, S., Wallaschek, N., Dubuc, I., Gravel, A., Journal of Virology, 2017, 10.1128/JVI.00437-17

Comparison of early and recent influenza A(H1N1)pdm09 isolates harboring or not the H275Y neuraminidase mutation, in vitro and in animal models, Boivin, G., Kobinger, G., Dufresne, S.F., Marie-Ève-Hamelin, Fage, C., Venable, M.-C., Checkmahomed, L., Carbonneau, J., Tu, V., Abed, Y., Antiviral Research, 2018, 10.1016/j.antiviral.2018.09.007

Design and validation with influenza a virus of an aerosol transmission chamber for ferrets, Duchaine, C., Boivin, G., Girard, M., Checkmahomed, L., Carbonneau, J., Rhéaume, C., Lévesque, A., Verreault, D., Hamelin, M.-È., Turgeon, N., International Journal of Environmental Research and Public Health, 2019, 10.3390/ijerph16040609

Validation of the Seegene RV15 multiplex PCR for the detection of influenza A subtypes and influenza B lineages during national influenza surveillance in hospitalized adults, McNeil, S.A., Ye, L., Webster, D., Valiquette, L., Trottier, S., Smyth, D., Shinde, V., Semret, M., Richardson, D., Powis, J., Poirier, A., McGeer, A., McElhaney, J.E., McCarthy, A., MacKinnon-Cameron, D., Lund, A., Loeb, M., Lagacé-Wiens, P., Langley, J.M., Katz, K., Johnstone, J., Ibarguchi, B., Hatchette, T.F., Halperin, S.A., Green, K., Dos Santos, G., Chit, A., Bowie, W., Boivin, G., Andrew, M., Ambrose, A., Warhuus, M., Mulpuru, S., ElSherif, M., LeBlanc, J.J., Journal of Medical Microbiology, 2020, 10.1099/jmm.0.001032

Tumor necrosis factor-alpha and interleukin-1 beta play a critical role in the resistance against lethal herpes simplex virus encephalitis., Boivin G, Rivest S, Sergerie Y, The Journal of infectious diseases, 2007, 10.1086/520094

The combination of oseltamivir with azithromycin does not show additional benefits over oseltamivir monotherapy in mice infected with influenza A(H1N1)pdm2009 virus, Boivin, G., Abed, Y., Rhéaume, C., Pizzorno, A., Fage, C., Journal of Medical Virology, 2017, 10.1002/jmv.24911

The impact of trained immunity in respiratory viral infections, Guy Boivin, Jocelyne Piret, Reviews in Medical Virology, 2024, 10.1002/rmv.2510

Antiviral resistance in herpes simplex virus and varicella-zoster virus infections: Diagnosis and management, Boivin, G., Piret, J., Current Opinion in Infectious Diseases, 2016, 10.1097/QCO.0000000000000288

Human parechovirus 3 and neonatal infections., Boucher FD, Abed Y, Boivin G, Emerging infectious diseases, 2005, 10.3201/eid1101.040606

Three-dimensional modeling of cytomegalovirus DNA polymerase and preliminary analysis of drug resistance., Lin SX, Boivin G, Gilbert C, Azzi A, Shi R, Proteins, 2006, 10.1002/prot.21005

Human metapneumovirus, the point ten years after its discovery. Genomic characteristics, virological and therapeutic advances,Le métapneumovirus humain, le point dix années après sa découverte. Caractéristiques génomiques, virologiques et avancées thérapeutiques, Boivin, G., Rosa-Calatrava, M., Feuillet, F., Virologie, 2011, 10.1684/vir.2011.0411

Comparison of Automated Microarray Detection with Real-Time PCR Assays for Detection of Respiratory Viruses in Specimens Obtained from Children, Corbeil J, Boivin G, De Serres G, Wu W, Boisvert S, Robitaille L, Boucher N, Carbonneau J, Raymond F, Journal of clinical microbiology, 2010

Effectiveness of Influenza Vaccination on Hospitalizations and Risk Factors for Severe Outcomes in Hospitalized Patients With COPD, Taylor, G., Smith, S., Poirier, A., Light, B., Lagace-Wiens, P., McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Smyth, D., Shinde, V., Semret, M., Richardson, D., Powis, J., McGeer, A., McElhaney, J.E., McCarthy, A., MacKinnon-Cameron, D., Loeb, M., LeBlanc, J., Langley, J.M., Katz, K., Johnstone, J., Ibarguchi, B., Halperin, S.A., Haguinet, F., Green, K., ElSherif, M., Dos Santos, G., Chit, A., Bowie, W., Boivin, G., Ambrose, A., Andrew, M.K., Hatchette, T., Ye, L., Li, L., Mulpuru, S., Chest, 2019, 10.1016/j.chest.2018.10.044

Incidence of cytomegalovirus UL97 and UL54 amino acid substitutions detected after 100 or 200 days of valganciclovir prophylaxis., Elston R, Ives J, Farhan M, Boivin G, Goyette N, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2012, 10.1016/j.jcv.2011.12.019

Generation and Characterization of Drug-Resistant Influenza B Viruses Selected In Vitro with Baloxavir Acid, Guy Boivin, Julie Carbonneau, Yacine Abed, Amel Saim-Mamoun, Pathogens, 2022, 10.3390/pathogens11091048

The importance of frailty in the assessment of influenza vaccine effectiveness against influenza-related hospitalization in elderly people, McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Stiver, G., Semret, M., Richardson, D., Powis, J., Mcgeer, A., McCarthy, A., Mackinnon-Cameron, D., Loeb, M., Leblanc, J., Langley, J., Katz, K., Johnstone, J., Ibarguchi, B., Halperin, S., Green, K., Elsherif, M., Chit, A., Bowie, W., Boivin, G., Ambrose, A., Mcelhaney, B.J.E., Santos, G.D., Haguinet, F., Hatchette, T., Ye, L., Shinde, V., Andrew, M.K., Journal of Infectious Diseases, 2017, 10.1093/infdis/jix282

Seroprevalence of SARS-CoV-2 Antibodies Among Children in School and Day Care in Montreal, Canada, Caroline Quach, Gaston De Serres, Guy Boivin, Patrica Conrod, Cat Tuong Nguyen, Isabel Laurin, Nathalie Ratté, Nancy Haley, Alexander Apostolatos, Geneviève Fortin, Ashley Savard, Monica Zahreddine, Julie Carbonneau, Katia Charland, Marie-Ève Hamelin, Jesse Papenburg, Islem Cheriet, Alexandra Otis, Adrien Saucier, Laura Pierce, Noémie Bourque, Britt McKinnon, Kate Zinszer, JAMA Network Open, 2021, 10.1001/jamanetworkopen.2021.35975

Divergent evolution of hemagglutinin and neuraminidase genes in recent influenza A:H3N2 viruses isolated in Canada., Boivin G, Li Y, Hardy I, Abed Y, Journal of medical virology, 2002, 10.1002/jmv.10143

Oseltamivir-resistant pandemic A/H1N1 virus is as virulent as its wild-type counterpart in mice and ferrets., Boivin G, Kobinger GP, Schumer G, Mallett C, Plante M, Bellerose N, Beaulieu E, Joubert P, Couture C, Abed Y, Baz M, Hamelin ME, PLoS pathogens, 2010, 10.1371/journal.ppat.1001015

SARS-CoV-2 seroprevalence and mental health of school staff: a cross-sectional study of schools from four areas of Montreal, Quebec in 2021, Kate Zinszer, Caroline Quach, Guy Boivin, Jesse Papenburg, Gaston De Serres, Cat Tuong Nguyen, Julie Carbonneau, Margot Barbosa Da Torre, Marie-Eve Hamelin, Laura Pierce, Adrien Saucier, Eleanor Greenspan-Ardman, Matteo Pannunzio, Katia Charland, BMJ Open, 2024, 10.1136/bmjopen-2023-081838

Phenotypic evaluation of previously uncharacterized cytomegalovirus DNA polymerase sequence variants detected in a valganciclovir treatment trial, Elston, R., Ives, J., Boivin, G., Chou, S., Journal of Infectious Diseases, 2014, 10.1093/infdis/jit654

Human metapneumovirus., Boivin G, Hamelin ME, Deffrasnes C, Seminars in respiratory and critical care medicine, 2007, 10.1055/s-2007-976493

Detection of ganciclovir resistance mutations quantitation of cytomegalovirus (CMV) DNA in leukocytes of patients with fatal disseminated CMV disease., Jordan MC, Erice A, Quirk MR, Chou S, Boivin G, The Journal of infectious diseases, 1996, 10.1093/infdis/173.3.523

Quantification of human herpesvirus 8 by real-time PCR in blood fractions of AIDS patients with Kaposi's sarcoma and multicentric Castleman's disease., Routy JP, Maguigad M, Abed Y, Cloutier N, Côté S, Boivin G, Journal of medical virology, 2002, 10.1002/jmv.10217

Predicting influenza infections during epidemics with use of a clinical case definition., Maziade J, Tellier G, Hardy I, Boivin G, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2000, 10.1086/317425

Viral Loads of Pneumoviruses: Correlation With Coinfection Rates and Disease Severity, Guy Boivin, Rodica Gilca, Marie‐Eve Hamelin, Julie Carbonneau, Sarah Talah, Journal of Medical Virology, 2024, 10.1002/jmv.70054

Viral Interference between Respiratory Viruses., Boivin G, Piret J, Emerging infectious diseases, 2022, 10.3201/eid2802.211727

Presence of oseltamivir-resistant pandemic A/H1N1 minor variants before drug therapy with subsequent selection and transmission., Boivin G, Papenburg J, Hamelin ME, Fitch A, Pinilla LT, DePasse JV, Holmes EC, Ghedin E, The Journal of infectious diseases, 2012, 10.1093/infdis/jis571

Viral Fitness of Baloxavir-Resistant Recombinant Influenza B/Victoria- and B/Yamagata-like Viruses Harboring the I38T PA Change, In Vitro, Ex Vivo and in Guinea Pigs, Guy Boivin, Yacine Abed, Chantal Rhéaume, Julie Carbonneau, Amel Saim-Mamoun, Microorganisms, 2023, 10.3390/microorganisms11051095

Infection with human metapneumovirus predisposes mice to severe pneumococcal pneumonia., Boivin G, Bergeron MG, Bergeron Y, Gagnon C, Prince GA, Hamelin ME, Kukavica-Ibrulj I, Journal of virology, 2008, 10.1128/jvi.01123-08

Strain-dependent impact of G and SH deletions provide new insights for live-attenuated HMPV vaccine development, Boivin, G., Rosa-Calatrava, M., Terrier, O., Hamelin, M.-È., Lina, B., Couture, C., Lavigne, S., Julien, T., Traversier, A., Carbonneau, J., Venable, M.-C., Uyar, O., De Lamballerie, C.N., Padey, B., Cavanagh, M.-H., Pizzorno, A., Dubois, J., Vaccines, 2019, 10.3390/vaccines7040164

Cytomegalovirus seropositivity is associated with increased microbial translocation in people living with human immunodeficiency virus and uninfected controls, Routy, J.-P., Boivin, G., Ancuta, P., Tremblay, C., Durand, M., Chartrand-Lefebvre, C., Lebouché, B., Costiniuk, C., Finkelman, M., Zhang, Y., Mehraj, V., Ouyang, J., Fombuena, B., Lin, J., Isnard, S., Ramendra, R., Clinical Infectious Diseases, 2020, 10.1093/cid/ciz1001

Development of a universal influenza A vaccine based on the M2e peptide fused to the papaya mosaic virus (PapMV) vaccine platform., Leclerc D, Boivin G, Lopez Macias C, Lopez Macias C, Pare C, Savard C, Abed Y, Baz M, Koukavica I, Hamelin ME, Zhao Y, Acosta-Ramirez E, Denis J, Vaccine, 2008, 10.1016/j.vaccine.2008.04.052

Evolution of oseltamivir resistance mutations in influenza A(H1N1) and A(H3N2) viruses during selection in experimentally infected mice, Boivin, G., Corbeil, J., Hamelin, M.-È., Baz, M., Carbonneau, J., Plante, P.-L., Abed, Y., Pizzorno, A., Antimicrobial Agents and Chemotherapy, 2014, 10.1128/AAC.02956-14

Risk factors for hospitalization and severe outcomes of 2009 pandemic H1N1 influenza in Quebec, Canada, Skowronski, D.M., Boivin, G., Dionne, M., Fortin, E., Douville-Fradet, M., Ouhoummane, N., Papenburg, J., Boulianne, N., de Serres, G., Gilca, R., Influenza and other Respiratory Viruses, 2011, 10.1111/j.1750-2659.2011.00204.x

Canadian consensus guidelines for the management of cytomegalovirus disease in HIV/AIDS., Walmsley S, Shafran SD, Phillips P, Lindley JI, Klein AH, Hopkins JJ, Hodge WG, Deschênes J, Boivin G, Lalonde RG, The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2004, 10.1155/2004/369390

Older Age and Frailty are Associated with Higher Mortality but Lower ICU Admission with COVID-19, Shelly A. McNeil, Anne McCarthy, Kevin Katz, Stephanie W. Smith, Mark Loeb, Sylvie Trottier, Ardith Ambrose, Kevin Wilson, Donna MacKinnon-Cameron, May ElSherif, Todd F. Hatchette, Janet E. McElhaney, Allison McGeer, Louis Valiquette, Guy Boivin, Jason LeBlanc, Judith Godin, Melissa Andrew, Canadian Geriatrics Journal, 2022, 10.5770/cgj.25.546

Molecular characterization of a Canadian human parechovirus (HPeV)-3 isolate and its relationship to other HPeVs., Boivin G, Abed Y, Journal of medical virology, 2005, 10.1002/jmv.20493

A reverse genetics study of resistance to neuraminidase inhibitors in an influenza A/H1N1 virus., Boivin G, Goyette N, Abed Y, Antiviral therapy, 2004

Epidemiology of Influenza Viruses in Canada over the 2011–2012 to 2013–2014 Seasons: A Study from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN), Shelly McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Daniel Smyth, Makeda Semret, David Richardson, Jeff Powis, Michaela Nichols, Allison Mcgeer, Janet McElhaney, Anne Mccarthy, Donna Mackinnon-Cameron, Mark Loeb, Kevin Katz, Karen Green, William R Bowie, Guy Boivin, Ardith Ambrose, Melissa K Andrew, Lingyun Ye, Jason Leblanc, Todd Hatchette, May Elsherif, Open Forum Infectious Diseases, 2017, 10.1093/ofid/ofx163.735

Optimization of Droplet Digital PCR from RNA and DNA extracts with direct comparison to RT-qPCR: Clinical implications for quantification of Oseltamivir-resistant subpopulations, Boivin, G., Shelton, D.N., Carbonneau, J., Taylor, S.C., Journal of Virological Methods, 2015, 10.1016/j.jviromet.2015.08.014

Épidémiologie et impact clinique des nouveaux virus respiratoires., Boivin G, Hamelin ME, Revue des maladies respiratoires actualites, 2009, 10.1016/s1877-1203(09)75275-9

Fitness of influenza A and B viruses with reduced susceptibility to baloxavir: A mini-review, Boivin, G., Saim-Mamoun, A., Abed, Y., Reviews in Medical Virology, 2021, 10.1002/rmv.2175

Human herpesvirus 8 DNA load in leukocytes of human immunodeficiency virus-infected subjects: correlation with the presence of Kaposi's sarcoma and response to anticytomegalovirus therapy., Bergeron MG, Handfield J, Murray G, Routy JP, Lalonde R, Toma E, Gaudreau A, Boivin G, Antimicrobial agents and chemotherapy, 1999, 10.1128/aac.43.2.377

Development and validation of an enzyme-linked immunosorbent assay for human metapneumovirus serology based on a recombinant viral protein., Boivin G, Hamelin ME, Clinical and diagnostic laboratory immunology, 2005, 10.1128/cdli.12.2.249-253.2005

Adjuvanted inactivated influenza A(H3N2) vaccines induce stronger immunogenicity in mice and confer higher protection in ferrets than unadjuvanted inactivated vaccines, Boivin, G., Papadopoulou, B., Hamelin, M.-E., Mallett, C., Morasse, A., Beaulieu, E., Dumas, C., Rheaume, C., Samant, M., Ann, J., Vaccine, 2014, 10.1016/j.vaccine.2014.08.029

Structural Insight into NS5 of Zika Virus Leading to the Discovery of MTase Inhibitors, Lin, S.-X., Boivin, G., Baz, M., Stephen, P., Journal of the American Chemical Society, 2016, 10.1021/jacs.6b10399

Recombinant phenotyping of cytomegalovirus UL54 mutations that emerged during cell passages in the presence of either ganciclovir or foscarnet., Boivin G, Lin SX, Goyette N, Azzi A, Gilbert C, Antimicrobial agents and chemotherapy, 2011, 10.1128/aac.00334-11

Human cytomegalovirus resistance to antiviral drugs., Boivin G, Gilbert C, Antimicrobial agents and chemotherapy, 2005, 10.1128/aac.49.3.873-883.2005

Analysis of cytomegalovirus DNA polymerase (UL54) mutations in solid organ transplant patients receiving valganciclovir or ganciclovir prophylaxis., Covington E, Gilbert C, Goyette N, Boivin G, Journal of medical virology, 2005, 10.1002/jmv.20471

OVX836 a recombinant nucleoprotein vaccine inducing cellular responses and protective efficacy against multiple influenza A subtypes, Hill, F., Marvel, J., Rosa-Calatrava, M., Leverrier, Y., Le Vert, A., Nicolas, F., Hamelin, M.-E., Boivin, G., Lina, B., Pérez-Vargas, J., Haller, M., Bouley, J., Djebali, S., Pizzorno, A., Del Campo, J., npj Vaccines, 2019, 10.1038/s41541-019-0098-4

Influenzavirus infection is a primary cause of febrile respiratory illness in HIV-infected adults, despite vaccination., Boivin G, Coté S, DelBalso L, Lu Y, Klein MB, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, 10.1086/518986

Comparison of automated microarray detection with real-time PCR assays for detection of respiratory viruses in specimens obtained from children., Corbeil J, Boivin G, De Serres G, Wu WK, Boisvert S, Robitaille L, Boucher N, Carbonneau J, Raymond F, Journal of clinical microbiology, 2009, 10.1128/jcm.01297-08

Infections by human coronavirus-NL in hospitalized children., De Serres G, Déry P, Bergeron MG, Leblanc E, Deffrasnes C, Gilca R, Côté S, Baz M, Boivin G, The Pediatric infectious disease journal, 2005, 10.1097/01.inf.0000183743.68569.c7

Characterization of contemporary influenza B recombinant viruses harboring mutations of reduced susceptibility to baloxavir marboxil, in vitro and in mice, Boivin, G., Venable, M.-C., Checkmahomed, L., Fage, C., Abed, Y., Antiviral Research, 2020, 10.1016/j.antiviral.2020.104807

Human metapneumovirus: a new player among respiratory viruses., Boivin G, Abed Y, Hamelin ME, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2004, 10.1086/382536

Antiviral drug resistance in herpesviruses other than cytomegalovirus, Boivin, G., Piret, J., Reviews in Medical Virology, 2014, 10.1002/rmv.1787

The distinguishing features of human metapneumovirus and respiratory syncytial virus., Boivin G, Papenburg J, Reviews in medical virology, 2010, 10.1002/rmv.651

Human metapneumovirus infection in immunocompromised child., Boivin G, Abed Y, Emerging infectious diseases, 2008, 10.3201/eid1405.071459

Antiviral drug resistance in herpesviruses, Boivin, G., Drouot, E., Piret, J., Handbook of Antimicrobial Resistance, 2017, 10.1007/978-1-4939-0694-9_7

Quantitative analysis of cytomegalovirus (CMV) viremia using the pp65 antigenemia assay and the COBAS AMPLICOR CMV MONITOR PCR test after blood and marrow allogeneic transplantation., Roy J, Goyette N, Demers C, Béliveau C, Delage R, Bélanger R, Boivin G, Journal of clinical microbiology, 2000, 10.1128/jcm.38.12.4356-4360.2000

Global genetic diversity of human metapneumovirus fusion gene., LeBlanc E, Gray GC, Ludewick H, Shemer-Avni Y, Wolf D, Freymuth F, Madhi S, Sloots TP, Mackay I, Boivin G, Emerging infectious diseases, 2004, 10.3201/eid1006.031097

Parental decisions regarding the vaccination of children and adolescents against SARS-CoV-2 from 2020 to 2023: A descriptive longitudinal study of parents and children in Montreal, Canada, Kate Zinszer, Guy Boivin, Julie Carbonneau, Marie-Ève Hamelin, Margot Barbosa Da Torre, Adrien Saucier, Cat Tuong Nguyen, Laura Pierce, Jesse Papenburg, Caroline Quach, Katia Charland, Vaccine, 2025, 10.1016/j.vaccine.2024.126489

Vaccine Effectiveness of non-adjuvanted and adjuvanted trivalent inactivated influenza vaccines in the prevention of influenza-related hospitalization in older adults: A pooled analysis from the Serious Outcomes Surveillance (SOS) Network of the Canadian Immunization Research Network (CIRN), Shelly A. McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Grant Stiver, Daniel Smyth, Stephanie Smith, Makeda Semret, David Richardson, Jeff Powis, Andre Poirier, Allison McGeer, Anne McCarthy, Mark Loeb, Phillipe Lagacé-Wiens, Kevin Katz, Jennie Johnstone, William Bowie, Guy Boivin, Ardith Ambrose, Jason LeBlanc, Todd Hatchette, May ElSherif, Lingyun Ye, Michaela K. Nichols, Zachary Shaffelburg, Melissa Andrew, POTT, H, Vaccine, 2023, 10.1016/j.vaccine.2023.08.070

Influenza A virus interferes with respiratory syncytial virus in mice and reconstituted human airway epithelium, Guy Boivin, Christian Couture, Nathalie Goyette, Julie Carbonneau, Chantal Rhéaume, Jocelyne Piret, Shella Gilbert-Girard, Microbiology Spectrum, 2025, 10.1128/spectrum.03187-24

Evaluation of a rapid optical immunoassay for influenza viruses (FLU OIA test) in comparison with cell culture and reverse transcription-PCR., Kress A, Hardy I, Boivin G, Journal of clinical microbiology, 2001, 10.1128/jcm.39.2.730-732.2001

Sequence polymorphism of the predicted human metapneumovirus G glycoprotein., Boivin G, Erdman DD, Anderson LJ, Abed Y, Peret TCT, The Journal of general virology, 2004, 10.1099/vir.0.19504-0

Respiratory tract reinfections by the new human Metapneumovirus in an immunocompromised child., Boivin G, Abed Y, Déry P, Pelletier G, Emerging infectious diseases, 2002, 10.3201/eid0809.020238

An outbreak of severe respiratory tract infection due to human metapneumovirus in a long-term care facility., Couture C, Boulianne N, Ouakki M, Sauvageau C, Maranda-Aubut R, Tremblay G, Argouin M, Côté S, Hamelin ME, De Serres G, Boivin G, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2007, 10.1086/513204

Viral interference between severe acute respiratory syndrome coronavirus 2 and influenza A viruses, Guy Boivin, Nathalie Goyette, Mathilde Hénaut, Julie Carbonneau, Jocelyne Piret, Shella Gilbert-Girard, 2024, 10.1101/2024.02.02.578538

Quantification of the influenza virus load by real-time polymerase chain reaction in nasopharyngeal swabs of patients treated with oseltamivir., Wat C, Coulombe Z, Boivin G, The Journal of infectious diseases, 2003, 10.1086/377046

Streptococcus pneumoniae serotype 3 is masking PCV13-mediated herd immunity in Canadian adults hospitalized with community acquired pneumonia: A study from the Serious Outcomes Surveillance (SOS) Network of the Canadian immunization research Network (CIRN), McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Semret, M., McGeer, A., McCarthy, A.E., Loeb, M., Johnstone, J., Green, K., Bowie, W., Boivin, G., Andrew, M.K., Demczuk, W., Martin, I., Gillis, H.D., Lang, A.L.S., Hatchette, T.F., Ambrose, A., MacKinnon-Cameron, D., Ye, L., ElSherif, M., LeBlanc, J.J., Vaccine, 2019, 10.1016/j.vaccine.2019.05.003

Human cytomegalovirus glycoprotein B genotypes in blood of AIDS patients: lack of association with either the viral DNA load in leukocytes or presence of retinitis., Boivin G, Bergeron MG, Lalonde R, Toma E, Handfield J, Gilbert C, Journal of medical virology, 1999, 10.1002/(sici)1096-9071(199909)59:1<98::aid-jmv16>3.0.co;2-a

Cross-reactive and vaccine-induced antibody to an emerging swine-origin variant of influenza A virus subtype H3N2 (H3N2v)., Li Y, Boivin G, Petric M, Bastien N, Li G, Gardy JL, Sabaiduc S, Dionne M, Scheifele DW, Gilca V, Purych D, De Serres G, Janjua NZ, Skowronski DM, The Journal of infectious diseases, 2012, 10.1093/infdis/jis500

Resistance of herpesviruses to antiviral drugs: clinical impacts and molecular mechanisms., Boivin G, Bestman-Smith J, Gilbert C, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 2002, 10.1016/s1368-7646(02)00021-3

Novel calixarene-based surfactant enables low dose split inactivated vaccine protection against influenza infection, Jawhari, A., Rosa-Calatrava, M., Dejean, E., Boivin, G., Lina, B., Hamelin, M.E., Champagne, A., Traversier, A., Pizzorno, A., Mandon, E.D., Vaccine, 2020, 10.1016/j.vaccine.2019.10.018

Seroconversion to seasonal influenza viruses after A(H1N1)pdm09 virus infection, Quebec, Canada., Boivin G, De Serres G, Skowronski DM, Ouakki M, Hamelin ME, Papenburg J, Baz M, Emerging infectious diseases, 2012, 10.3201/eid1807.111680

Human metapneumovirus infection induces long-term pulmonary inflammation associated with airway obstruction and hyperresponsiveness in mice., Boivin G, Kinkead R, Gomez AM, Prince GA, Hamelin ME, The Journal of infectious diseases, 2006, 10.1086/504262

The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-organ Transplantation., The Transplantation Society International CMV Consensus Group, Humar A, Danziger-Isakov L, Chou S, Huprikar S, Caliendo AM, Kumar D, Kotton CN, Transplantation, 2018, 10.1097/tp.0000000000002191

Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model., Boivin G, Riteau B, Vergnolle N, Seidah NG, Prat A, Susan-Resiga D, Kim W, Couture C, Lavigne S, Rhéaume C, Hamelin MÈ, Aerts L, PloS one, 2013, 10.1371/journal.pone.0072529

The cost-effectiveness and value of information of three influenza vaccination dosing strategies for individuals with human immunodeficiency virus., CIHR Canadian HIV Trials Network Influenza Vaccine Research Group, Anis AH, Cooper C, Sun H, Sharif B, Nosyk B, PloS one, 2011, 10.1371/journal.pone.0027059

Prophylactic and therapeutic benefits of a monoclonal antibody against the fusion protein of human metapneumovirus in a mouse model., Boivin G, Ulbrandt N, Suzich J, Kiener P, Prince GA, Gagnon C, Hamelin ME, Antiviral research, 2010, 10.1016/j.antiviral.2010.07.001

A Review of Clinical Influenza A and B Infections With Reduced Susceptibility to Both Oseltamivir and Zanamivir., Boivin G, Abed Y, Open forum infectious diseases, 2017, 10.1093/ofid/ofx105

Human parechovirus types 1, 2 and 3 infections in Canada., Boivin G, Abed Y, Emerging infectious diseases, 2006, 10.3201/eid1206.051675

Synergistic PA and HA mutations confer mouse adaptation of a contemporary A/H3N2 influenza virus, Boivin, G., Abed, Y., Couture, C., Lavigne, S., Carbonneau, J., M’hamdi, Z., Baz, M., Scientific Reports, 2019, 10.1038/s41598-019-51877-4

Role of permissive neuraminidase mutations in influenza A/Brisbane/59/2007-like (H1N1) viruses, Boivin, G., Bouhy, X., Pizzorno, A., Abed, Y., PLoS Pathogens, 2011, 10.1371/journal.ppat.1002431

Opposite effect of two cytomegalovirus DNA polymerase mutations on replicative capacity and polymerase activity., Boivin G, Lin SX, Azzi A, Martin M, Antiviral therapy, 2010, 10.3851/imp1565

Symptomatology during previous SARS-CoV-2 infection and serostatus before vaccination influence the immunogenicity of BNT162b2 COVID-19 mRNA vaccine, Hélène Decaluwe, Caroline Quach, Guy Boivin, Mariana Baz, Vladimir Gilca, Jacques Corbeil, Gaston De Serres, Matthew P. Cheng, Yves Longtin, Patrice Savard, Deirdre McCormack, Marie-Ève Hamelin, Henintsoa Rabezanahary, Julie Carbonneau, Kelsey Adams, Benoîte Bourdin, Sabryna Nantel, Frontiers in Immunology, 2022, 10.3389/fimmu.2022.930252

Impact of COVID-19 and Vaccination During Pregnancy on Placenta-Mediated Complications (COVIGRO Study), Emmanuel Bujold, Julie Carbonneau, Gina Muckle, Marie-Eve Hamelin, Jean-Claude Forest, Yves Giguere, Brielle Demuth, Guy Boivin, Louise Ghesquiere, Journal of Obstetrics and Gynaecology Canada, 2024, 10.1016/j.jogc.2023.102291

1325. Recalibrating Estimates of Pneumococcal Disease in Hospitalized Canadian adults from 2010 to 2017 with Use of an Extended Spectrum Serotype-specific Urine Antigen Detection, Shelly McNeil, Duncan Webster, Louis Valiquette, Sylvie Trottier, Makeda Semret, Allison McGeer, Anne McCarthy, Mark Loeb, Jennie Johnstone, Karen Green, William Bowie, Guy Boivin, Melissa K Andrew, Walter Demczuk, Irene Martin, Hayley D Gillis, Amanda L S Lang, Todd F Hatchette, Ardith Ambrose, Donna MacKinnon-Cameron, Lingyun Ye, May ElSherif, Jason J LeBlanc, Open Forum Infectious Diseases, 2021, 10.1093/ofid/ofab466.1517

Low systemic ganciclovir exposure and preemptive treatment failure of cytomegalovirus reactivation in a transplanted child., Ovetchkine P, Boivin G, Tapiéro B, Rousseau C, Duval M, Launay E, Théôret Y, Autmizguine J, Journal of population therapeutics and clinical pharmacology = Journal de la therapeutique des populations et de la pharmacologie clinique, 2011

Hypersusceptibility of human cytomegalovirus to foscarnet induced by mutations in helices K and P of the viral DNA polymerase, Boivin, G., Shi, R., Piret, J., Pham, V.D., Zarrouk, K., Antimicrobial Agents and Chemotherapy, 2020, 10.1128/AAC.01910-19

Antibody persistence and response to 2010-2011 trivalent influenza vaccine one year after a single dose of 2009 AS03-adjuvanted pandemic H1N1 vaccine in children, Skowronski, D., Gilca, R., Dionne, M., Sauvageau, C., Boulianne, N., Ouakki, M., Boivin, G., Hamelin, M.-E., De Serres, G., Gilca, V., Vaccine, 2011, 10.1016/j.vaccine.2011.10.062

Quantitation of cytomegalovirus DNA and characterization of viral gene expression in bronchoalveolar cells of infected patients with and without pneumonitis., Jordan MC, Hertz MI, Kringstad B, Quirk MR, Olson CA, Boivin G, The Journal of infectious diseases, 1996, 10.1093/infdis/173.6.1304

Cytomegalovirus resistance in solid organ transplant recipients treated with intravenous ganciclovir or oral valganciclovir., Humar A, Hartmann A, Ives J, Asberg A, Pescovitz MD, Jardine AG, Rollag H, Goyette N, Boivin G, Antiviral therapy, 2009

Activity of the neuraminidase inhibitor A-315675 against oseltamivir-resistant influenza neuraminidases of N1 and N2 subtypes., Boivin G, Baz M, Nehmé B, Abed Y, Antiviral research, 2007, 10.1016/j.antiviral.2007.08.008

Pathogenicity and response to topical antiviral therapy in a murine model of acyclovir-sensitive and acyclovir-resistant herpes simplex viruses isolated from the same patient., Boivin G, Lebel A, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2006, 10.1016/j.jcv.2006.05.003

Both cerebral and hematopoietic deficiencies in CCR2 result in uncontrolled herpes simplex virus infection of the central nervous system in Mice, Boivin, G., Gosselin, J., Piret, J., Canivet, C., Menasria, R., PLoS ONE, 2016, 10.1371/journal.pone.0168034

In vitro and in vivo evidence of a potential A(H1N1)pdm09 antigenic drift mediated by escape mutations in the haemagglutinin Sa antigenic site, Boivin, G., Baz, M., Rhéaume, C., Abed, Y., Retama, M., Journal of General Virology, 2017, 10.1099/jgv.0.000800

High and low flowrate sampling of airborne influenza in hospital rooms during three outbreaks, Caroline Duchaine, Guy Boivin, Bianka Paquet-Bolduc, Nathalie Turgeon, Marc Veillette, Jodelle Degois, Marie-Eve Dubuis, Journal of Aerosol Science, 2021, 10.1016/j.jaerosci.2021.105824

Contrasting effects of W781V and W780V mutations in helix N of herpes simplex virus 1 and human cytomegalovirus DNA polymerases on antiviral drug susceptibility., Boivin G, Götte M, Drouot E, Eckenroth BE, Goyette N, Piret J, Journal of virology, 2015, 10.1128/jvi.03360-14

Ten years of human metapneumovirus research, Boivin, G., Rosa-Calatrava, M., Lina, B., Feuillet, F., Journal of Clinical Virology, 2012, 10.1016/j.jcv.2011.10.002

Generation and characterization of recombinant influenza A (H1N1) viruses harboring amantadine resistance mutations., Boivin G, Goyette N, Abed Y, Antimicrobial agents and chemotherapy, 2005, 10.1128/aac.49.2.556-559.2005

Development of a serological assay based on a synthetic peptide selected from the VP0 capsid protein for detection of human parechoviruses., Boivin G, Dagan R, Wolf D, Abed Y, Journal of clinical microbiology, 2007, 10.1128/jcm.02432-06

Human metapneumovirus viral load is an important risk factor for disease severity in young children, Boivin, G., De Serres, G., Hamelin, M.-T., Papenburg, J., Ouakki, M., Carbonneau, J., Roussy, J.-F., Journal of Clinical Virology, 2014, 10.1016/j.jcv.2014.03.001

Permissive changes in the neuraminidase play a dominant role in improving the viral fitness of oseltamivir-resistant seasonal influenza A(H1N1) strains, Boivin, G., Bouhy, X., Pizzorno, A., Abed, Y., Antiviral Research, 2015, 10.1016/j.antiviral.2014.12.006

In Vitro Selection of Remdesivir-Resistant SARS-CoV-2 Demonstrates High Barrier to Resistance, Guy Boivin, Danielle P. Porter, Jiani Li, Jason K. Perry, Nicholas C. Riola, Venice Du Pont, Liva Checkmahomed, 2022, 10.1101/2022.02.07.479493

Genetic diversity between human metapneumovirus subgroups., Buchholz UJ, Collins PL, Murphy BR, Hanson CT, Boivin G, Skiadopoulos MH, Biacchesi S, Virology, 2003, 10.1016/s0042-6822(03)00528-2

Viral pathogens including human metapneumovirus are the primary cause of febrile respiratory illness in HIV-infected adults receiving antiretroviral therapy., Boivin G, Frost E, Carbonneau J, DelBalso L, Yang H, Klein MB, The Journal of infectious diseases, 2010, 10.1086/649587

Frailty hinders recovery from influenza and acute respiratory illness in older adults, Andrew, M.K., Webster, D., Semret, M., Powis, J., Poirier, A., McGeer, A., Boivin, G., Bowie, W., LeBlanc, J., Hatchette, T.F., Loeb, M., McNeil, S.A., McElhaney, J.E., Godin, J., Lees, C., Journal of Infectious Diseases, 2020, 10.1093/infdis/jiaa092

Impact of neuraminidase mutations conferring influenza resistance to neuraminidase inhibitors in the N1 and N2 genetic backgrounds., Boivin G, Baz M, Abed Y, Antiviral therapy, 2006

Replication and transmission of an influenza A(H3N2) virus harboring the polymerase acidic I38T substitution, in guinea pigs., Guy Boivin, Yacine Abed, Mariana Baz, Marie-Christine Venable, Julie Carbonneau, Zeineb Mhamdi, Journal of General Virology, 2021, 10.1099/jgv.0.001659

Generation and characterization of recombinant pandemic influenza A(H1N1) viruses resistant to neuraminidase inhibitors., Boivin G, Abed Y, Bouhy X, Pizzorno A, The Journal of infectious diseases, 2011, 10.1093/infdis/jiq010

Reply, Boivin G, The Journal of infectious diseases, 2000, 10.1086/315668

992. 2016–2017 Influenza Burden of Disease and End-of-Season Influenza Vaccine Effectiveness (VE) Estimates for Preventing Influenza-Related Hospitalization Among Canadian Adults: An Analysis From the Canadian Immunization Research Network (CIRN) Serious Outcomes Surveillance (SOS) Network, Shelly A McNeil, Lingyun Ye, Duncan Webster, Louis Valiquette, Sylvie Trottier, Daniel Smyth, Makeda Semret, David Richardson, Jeff Powis, Andre Poirier, Allison McGeer, Janet McElhaney, Anne Mccarthy, Donna Mackinnon-Cameron, Mark Loeb, Jason Leblanc, Kevin Katz, Jennie Johnstone, Karen Green, May Elsherif, Guy Boivin, Ardith Ambrose, Todd F Hatchette, Melissa K Andrew, Michaela Nichols, Open Forum Infectious Diseases, 2018, 10.1093/ofid/ofy210.829

Importance of viral and bacterial infections in chronic obstructive pulmonary disease exacerbations., Boivin G, Barret B, Weiss K, Bourbeau J, Rouleau I, La Forge J, Lampron N, De Serres G, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2009, 10.1016/j.jcv.2009.07.010

Impact of the H275Y and I223V mutations in the neuraminidase of the 2009 pandemic influenza virus in vitro and evaluating experimental reproducibility, Beauchemin, C.A.A., Boivin, G., Abed, Y., Holder, B.P., Pinilla, L.T., Paradis, E.G., PLoS ONE, 2015, 10.1371/journal.pone.0126115

1365 The incidence of community acquired pneumonia by occupation, Shelly McNeil, Wanda Allen, Stephanie Carson, Anne McCarthy, Isabelle Chabot, Guy Boivin, Sylvie Trottier, Stefanie Materniak, Duncan Webster, Ardith Ambrose, Donna MacKinnon-Cameron, Anne Theriault, Anil Adisesh, Infectious Occupational Agents, 2018, 10.1136/oemed-2018-icohabstracts.596

Human bocavirus infections in hospitalized children and adults., Boivin G, Bergeron MG, de Serres G, Leblanc E, Gilca R, Bastien M, Longtin J, Emerging infectious diseases, 2008, 10.3201/eid1402.070851

Mucosal bivalent live attenuated vaccine protects against human metapneumovirus and respiratory syncytial virus in mice, Julia Dubois, Manuel Rosa-Calatrava, Guy Boivin, Andrés Pizzorno, Marie-Eve Hamelin, Julien Fouret, Jean-François Eléouët, stephane paul, Marie Galloux, Thomas Julien, Olivier Terrier, Aurélien Traversier, Victoria Dulière, Emilie Laurent, Julie Carbonneau, Clément Droillard, Caroline Chupin, Clémence Vacher, pauline brun, Daniela Ogonczyk-Makowska, npj Vaccines, 2024, 10.1038/s41541-024-00899-9

Age-stratified burden of pneumococcal community acquired pneumonia in hospitalised Canadian adults from 2010 to 2015, McNeil, S.A., Webster, D., Valiquette, L., Trottier, S., Semret, M., McGeer, A., McCarthy, A., Loeb, M., Johnstone, J., Green, K., Bowie, W., Boivin, G., Andrew, M.K., Laferriere, C., Demczuk, W.H., Martin, I., Gillis, H.D., Lang, A.L.S., Hatchette, T.F., Ambrose, A., Mackinnon-Cameron, D., Ye, L., Elsherif, M., Leblanc, J., BMJ Open Respiratory Research, 2020, 10.1136/bmjresp-2019-000550

Detection of human metapneumovirus antigens in nasopharyngeal aspirates using an enzyme immunoassay., Boivin G, Kukavica-Ibrulj I, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2008, 10.1016/j.jcv.2008.09.011

Herpesvirus Resistance, W.L. Drew, G. Boivin, Antimicrobial Drug Resistance, 2009, 10.1007/978-1-60327-595-8_24

Impact of a large deletion in the neuraminidase protein identified in a laninamivir-selected influenza A/Brisbane/10/2007 (H3N2) variant on viral fitness in vitro and in ferrets, Boivin, G., Mallett, C., Hamelin, M.-E., Carbonneau, J., Dubé, K., Joly, M.-H., Bouhy, X., Beaulieu, E., Abed, Y., Ann, J., Influenza and other Respiratory Viruses, 2016, 10.1111/irv.12356

Mutations in the fusion protein heptad repeat domains of human metapneumovirus impact on the formation of syncytia, Boivin, G., Rosa-Calatrava, M., Shi, R., Lina, B., Hamelin, M.È., Terrier, O., Cavanagh, M.-H., Dubois, J., Journal of General Virology, 2017, 10.1099/jgv.0.000796

A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis, Guy Boivin, Jacques Corbeil, Julie Carbonneau, Marie-Christine Venable, Jocelyne Piret, Pier-Luc Plante, Olus Uyar, Scientific Reports, 2021, 10.1038/s41598-021-98047-z

Adjuvant effect of the human metapneumovirus (HMPV) matrix protein in HMPV subunit vaccines, Boivin, G., Hamelin, M.-É.V., Couture, C., Lavigne, S., Carbonneau, J., Aume, C.R., Aerts, L., Journal of General Virology, 2015, 10.1099/vir.0.000031

Reply , Boivin G, The Journal of infectious diseases, 1998, 10.1086/314472

Comparison of the inhibition of human metapneumovirus and respiratory syncytial virus by ribavirin and immune serum globulin in vitro., Piedra PA, Boivin G, Jewell AM, Chetty SN, Wyde PR, Antiviral research, 2003, 10.1016/s0166-3542(03)00153-0

Combination therapy with oseltamivir and favipiravir delays mortality but does not prevent oseltamivir resistance in immunodeficient mice infected with pandemic A(H1N1) influenza virus, Boivin, G., Cavanagh, M.-H., Rhéaume, C., Carbonneau, J., Baz, M., Viruses, 2018, 10.3390/v10110610

Fitness of SARS-CoV-2 Omicron Subvariants in Respiratory and Gastrointestinal Cell Lines as Determined by Reverse-Transcription Droplet Digital PCR and Whole-Genome Sequencing, Guy Boivin, Inès Levade, Julie Carbonneau, Mathilde Hénaut, The Journal of Infectious Diseases, 2024, 10.1093/infdis/jiae554

DNA polymerases of herpesviruses and their inhibitors, Guy Boivin, Jocelyne Piret, Viral Replication Enzymes and their Inhibitors Part B, 2021, 10.1016/bs.enz.2021.07.003

In vitro combinations of baloxavir acid and other inhibitors against seasonal influenza a viruses, Boivin, G., Baz, M., Abed, Y., Rosa-Calatrava, M., Terrier, O., Pizzorno, A., Padey, B., Checkmahomed, L., Viruses, 2020, 10.3390/v12101139

Efficacy of Colchicine in Non-Hospitalized Patients with COVID-19, for the COLCORONA Investigators, Denault A, Dupuis J, Audet S, Verret L, da Luz P, Lopez-Sendon J, Pillinger MH, Shah B, Gaudet D, L’Allier PL, Bouabdallaoui N, Tardif J, 2021, 10.1101/2021.01.26.21250494

Protease-activated receptor 1 inhibition protects mice against thrombin-dependent respiratory syncytial virus and human metapneumovirus infections, Boivin, G., Hamelin, M.-È., Rhéaume, C., Jandrot-Perrus, M., Couture, C., Alessi, M.-C., Riteau, B., Lê, V.B., British Journal of Pharmacology, 2018, 10.1111/bph.14084

The nonstructural NS1 protein of influenza viruses modulates TP53 splicing through host factor CPSF4, Terrier, O., Rosa-Calatrava, M., Boivin, G., Marcel, V., Bourdon, J.-C., Lina, B., Padey, B., Julien, T., Traversier, A., Dubois, J., Journal of Virology, 2019, 10.1128/JVI.02168-18

Predominant role of IPS-1 over TRIF adaptor proteins in early innate immune response against Zika virus in mice, Boivin, G., Baz, M., Rhéaume, C., Carbonneau, J., Piret, J., Journal of General Virology, 2018, 10.1099/jgv.0.000992

Amphipathic DNA polymers exhibit antiherpetic activity in vitro and in vivo., Vaillant A, Juteau JM, Ireland J, Boivin G, Kern ER, Cardin R, Goyette N, Bernstein DI, Antimicrobial agents and chemotherapy, 2008, 10.1128/aac.00279-08

Comparative evaluation of real-time PCR assays for detection of the human metapneumovirus., Boivin G, Abed Y, Côté S, Journal of clinical microbiology, 2003, 10.1128/jcm.41.8.3631-3635.2003

Intravenous ciprofloxacin disposition in obesity., LeBel M, Sörgel F, Boivin G, Kinzig M, Allard S, Clinical pharmacology and therapeutics, 1993, 10.1038/clpt.1993.162

Highly reliable heterologous system for evaluating resistance of clinical herpes simplex virus isolates to nucleoside analogues., Boivin G, Papadopoulou B, Schmit I, Bestman-Smith J, Journal of virology, 2001, 10.1128/jvi.75.7.3105-3110.2001

Cytomegalovirus ventriculoencephalitis in a peripheral blood stem cell transplant recipient., Tang YW, Kassim A, Becher MW, McConnell T, Dummer JS, Boivin G, Miller GG, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2006, 10.1086/499366

Effect of the neuraminidase mutation H274Y conferring resistance to oseltamivir on the replicative capacity and virulence of old and recent human influenza A(H1N1) viruses., Boivin G, Hamelin ME, Simon P, Abed Y, Baz M, The Journal of infectious diseases, 2010, 10.1086/650464

Characterization of 2 influenza A(H3N2) clinical isolates with reduced susceptibility to neuraminidase inhibitors due to mutations in the hemagglutinin gene., Boivin G, Tisdale M, Owens IJ, Gower D, Morley PJ, Fenton RJ, Bourgault AM, Abed Y, The Journal of infectious diseases, 2002, 10.1086/344237

Hydroxyurea enhances the activity of acyclovir and cidofovir against herpes simplex virus type 1 resistant strains harboring mutations in the thymidine kinase and/or the DNA polymerase genes., Boivin G, Sergerie Y, Antiviral research, 2007, 10.1016/j.antiviral.2007.08.009

Genetics of symptom remission in outpatients with COVID-19, Tardif, J.-C., Busseuil, D., Boivin, G., Hussin, J., L’Allier, P.L., Gaudet, D., Nozza, A., Bassevitch, Z., Marchand, R., Bouabdallaoui, N., de Denus, S., Guertin, M.-C., Chabot-Blanchet, M., Cossette, M., Chicoine, L.-M., Savard, C., Goulet, E., Choi, J., Lousky, J., Dedelis, E., Valois, D., Dubois, A., Mongrain, I., Legault, M.-A., Sandoval, J., Sun, M., Provost, S., Asselin, G., Oussaïd, E., Lemieux Perreault, L.-P., Barhdadi, A., Lemaçon, A., Dubé, M.-P., Scientific Reports, 2021, 10.1038/s41598-021-90365-6

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Guy Boivin

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Thématiques de recherche de la Faculté de médecine

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