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Fernando Forato Anhe

Professeur sous octroi adjoint

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Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Santé cardiovasculaire, respiratoire et métabolisme

Domaines et intérêts de recherche du (de la) professeur(e) :

Nutrition et métabolisme
  • Diabète
  • Métabolisme
  • Métabolisme énergétique
  • Nutrition
  • Obésité
Microbiologie
  • Micro-organismes

Projets de recherche

  • Salaire professeur sous-octroi - Institut universitaire de cardiologie et de pneumologie de Québec, chercheur principal - 2022-07-01 au 2026-06-30
  • Étude de l'interaction microbe-hôte dans le contrôle du métabolisme de l'hôte - Fonds de recherche du Québec - Santé - Chercheur-boursier Juniors 1 et 2, Seniors, chercheur principal - 2022-07-01 au 2026-06-30
  • Étude de l'interaction microbe-hôte dans le contrôle du métabolisme de l'hôte - Subvention établissement de jeune chercheur - Fonds de recherche du Québec - Santé - Établissement de jeunes chercheurs - Juniors 1, chercheur principal - 2022-07-01 au 2026-06-30
  • Programme de soutien aux nouveaux chercheurs - Université Laval - Fonds internes - Soutien facultaire aux jeunes chercheurs de la Faculté de médecine, chercheur principal - 2022-07-01 au 2025-06-30
  • Testing the efficacy of ultrafiltration processes to lower postbiotic charge in chemically defined liquid diets - Fonds de recherche du Québec - Nature et technologies - Projet subsidiaire d'un regroupement stratégique (pour fins de gestion au VRRCI), chercheur principal - 2022-12-19 au 2024-03-31
  • Institut sur la nutrition et les aliments fonctionnels (INAF) - Institut national de recherche scientifique (INRS), Fonds de recherche du Québec - Nature et technologies, Université Laval - Fonds internes, Université McGill, Université du Québec à Rimouski, Université de Sherbrooke - Regroupements stratégiques NT, co-chercheur - 2017-04-01 au 2024-03-31
  • Demonstration of the prebiotic-like effects of camu-camu consumption against obesity-related disorders in humans - The W. Garfield Weston Foundation, co-chercheur - 2019-07-01 au 2022-06-30

Publications

  • Dietary sugar lowers immunity and microbiota that protect against metabolic disease. , Fernando Forato Anhê, Cell metabolism, 2022, 10.1016/j.cmet.2022.09.006
  • Gnotobiotic mice housing conditions critically influence the phenotype associated with transfer of faecal microbiota in a context of obesity, Fernando Forato Anhê, Gut, 2022, 10.1136/gutjnl-2021-326475
  • Human gut microbiota after bariatric surgery alters intestinal morphology and glucose absorption in mice independently of obesity., Fernando Forato Anhê, Gut, 2022, 10.1136/gutjnl-2022-328185
  • Life-long exercise training and inherited aerobic endurance capacity produce converging gut microbiome signatures in rodents., Anhê FF, Zlitni S, Barra NG, Foley KP, Nilsson MI, Nederveen JP, Koch LG, Britton SL, Tarnopolsky MA, Schertzer JD, Physiological reports, 2022, 10.14814/phy2.15215
  • Determining the metabolic impact of postbiotics in mice., Anhê FF, Bhatwa A, Schertzer JD, STAR protocols, 2022, 10.1016/j.xpro.2021.101098
  • Gut microbiota-based vaccination engages innate immunity to improve blood glucose control in obese mice., Duggan BM, Tamrakar AK, Barra NG, Anhê FF, Paniccia G, Wallace JG, Stacey HD, Surette MG, Miller MS, Sloboda DM, Schertzer JD, Molecular metabolism, 2021, 10.1016/j.molmet.2021.101404
  • Consistent gut bacterial and short-chain fatty acid signatures in hypoabsorptive bariatric surgeries correlate with metabolic benefits in rats., Mukorako P, Lemoine N, Biertho L, Lebel S, Roy MC, Plamondon J, Tchernof A, Varin TV, Anhê FF, St-Pierre DH, Marette A, Richard D, International journal of obesity (2005), 2021, 10.1038/s41366-021-00973-5
  • Lower brown adipose tissue activity is associated with non-alcoholic fatty liver disease but not changes in the gut microbiota., Ahmed BA, Ong FJ, Barra NG, Blondin DP, Gunn E, Oreskovich SM, Szamosi JC, Syed SA, Hutchings EK, Konyer NB, Singh NP, Yabut JM, Desjardins EM, Morrison KM, Cell reports. Medicine, 2021, 10.1016/j.xcrm.2021.100397
  • Metabolic endotoxemia is dictated by the type of lipopolysaccharide., Anhê FF, Barra NG, Cavallari JF, Henriksbo BD, Schertzer JD, Cell reports, 2021, 10.1016/j.celrep.2021.109691
  • Gut microbiota-based vaccination engages innate immunity to improve blood glucose control in obese mice, Duggan BM, Tamrakar AK, Barra NG, Anhê FF, Paniccia G, Wallace JG, Stacey HD, Miller MS, Sloboda DM, Schertzer JD, 2021, 10.1101/2021.07.15.452537
  • Metabolic endotoxemia is dictated by the type of lipopolysaccharide, Anhê FF, Barra NG, Cavallari JF, Henriksbo BD, Schertzer JD, 2021, 10.1101/2021.07.13.452270
  • Micronutrients impact the gut microbiota and blood glucose., Barra NG, Anhê FF, Cavallari JF, Singh AM, Chan DY, Schertzer JD, The Journal of endocrinology, 2021, 10.1530/joe-21-0081
  • Bacterial Postbiotics as Promising Tools to Mitigate Cardiometabolic Diseases., Anhê FF, Jensen BAH, Perazza LR, Tchernof A, Schertzer JD, Marette A, Journal of lipid and atherosclerosis, 2021, 10.12997/jla.2021.10.2.123
  • Gut microbiota impairs insulin clearance in obese mice., Foley KP, Zlitni S, Duggan BM, Barra NG, Anhê FF, Cavallari JF, Henriksbo BD, Chen CY, Huang M, Lau TC, Plante R, Schwab M, Marette A, Schertzer JD, Molecular metabolism, 2020, 10.1016/j.molmet.2020.101067
  • The NLRP3 inflammasome regulates adipose tissue metabolism., Barra NG, Henriksbo BD, Anhê FF, Schertzer JD, The Biochemical journal, 2020, 10.1042/bcj20190472
  • Type 2 diabetes influences bacterial tissue compartmentalisation in human obesity., Anhê FF, Jensen BAH, Varin TV, Servant F, Van Blerk S, Richard D, Marceau S, Surette M, Biertho L, Lelouvier B, Schertzer JD, Tchernof A, Marette A, Nature metabolism, 2020, 10.1038/s42255-020-0178-9
  • Postbiotics for NOD2 require nonhematopoietic RIPK2 to improve blood glucose and metabolic inflammation in mice., Cavallari JF, Barra NG, Foley KP, Lee A, Duggan BM, Henriksbo BD, Anhê FF, Ashkar AA, Schertzer JD, American journal of physiology. Endocrinology and metabolism, 2020, 10.1152/ajpendo.00033.2020
  • Glucose alters the symbiotic relationships between gut microbiota and host physiology., Anhê FF, Barra NG, Schertzer JD, American journal of physiology. Endocrinology and metabolism, 2019, 10.1152/ajpendo.00485.2019
  • Bacteria to alleviate metabolic syndrome., Anhê FF, Schertzer JD, Marette A, Nature medicine, 2019, 10.1038/s41591-019-0516-1
  • Host-Microbe Interplay in the Cardiometabolic Benefits of Dietary Polyphenols., Anhê FF, Choi BSY, Dyck JRB, Schertzer JD, Marette A, Trends in endocrinology and metabolism: TEM, 2019, 10.1016/j.tem.2019.04.002
  • Immunometabolism Sentinels: Gut Surface T-Cells Regulate GLP-1 Availability., Barra NG, Anhê FF, Schertzer JD, Endocrinology, 2019, 10.1210/en.2019-00215
  • Targeting macrophage scavenger receptor 1 promotes insulin resistance in obese male mice., Cavallari JF, Anhê FF, Foley KP, Denou E, Chan RW, Bowdish DME, Schertzer JD, Physiological reports, 2018, 10.14814/phy2.13930
  • Treatment with camu camu (Myrciaria dubia) prevents obesity by altering the gut microbiota and increasing energy expenditure in diet-induced obese mice., Anhê FF, Nachbar RT, Varin TV, Trottier J, Dudonné S, Le Barz M, Feutry P, Pilon G, Barbier O, Desjardins Y, Roy D, Marette A, Gut, 2018, 10.1136/gutjnl-2017-315565
  • Loss of OcaB Prevents Age-Induced Fat Accretion and Insulin Resistance by Altering B-Lymphocyte Transition and Promoting Energy Expenditure., Carter S, Miard S, Caron A, Sallé-Lefort S, St-Pierre P, Anhê FF, Lavoie-Charland E, Blais-Lecours P, Drolet MC, Lefebvre JS, Lacombe J, Deshaies Y, Picard F, Diabetes, 2018, 10.2337/db17-0558
  • Arctic berry extracts target the gut-liver axis to alleviate metabolic endotoxaemia, insulin resistance and hepatic steatosis in diet-induced obese mice., Anhê FF, Varin TV, Le Barz M, Pilon G, Dudonné S, Trottier J, St-Pierre P, Harris CS, Lucas M, Lemire M, Dewailly É, Barbier O, Desjardins Y, Roy D, Marette A, Diabetologia, 2017, 10.1007/s00125-017-4520-z
  • A polyphenol-rich cranberry extract reverses insulin resistance and hepatic steatosis independently of body weight loss., Anhê FF, Nachbar RT, Varin TV, Vilela V, Dudonné S, Pilon G, Fournier M, Lecours MA, Desjardins Y, Roy D, Levy E, Marette A, Molecular metabolism, 2017, 10.1016/j.molmet.2017.10.003
  • The Gut Microbiota as a Mediator of Metabolic Benefits after Bariatric Surgery., Anhê FF, Varin TV, Schertzer JD, Marette A, Canadian journal of diabetes, 2017, 10.1016/j.jcjd.2017.02.002
  • A microbial protein that alleviates metabolic syndrome., Anhê FF, Marette A, Nature medicine, 2017, 10.1038/nm.4261
  • Triggering Akkermansia with dietary polyphenols: A new weapon to combat the metabolic syndrome?, Anhê FF, Pilon G, Roy D, Desjardins Y, Levy E, Marette A, Gut microbes, 2016, 10.1080/19490976.2016.1142036
  • Comprehensive analysis of phenolic compounds and abscisic acid profiles of twelve native Canadian berries, Dudonné S, Dubé P, Anhê FF, Pilon G, Marette A, Lemire M, Harris C, Dewailly E, Desjardins Y, Journal of food composition and analysis : an official publication of the United Nations University, International Network of Food Data Systems, 2015, 10.1016/j.jfca.2015.09.003
  • Gut Microbiota Dysbiosis in Obesity-Linked Metabolic Diseases and Prebiotic Potential of Polyphenol-Rich Extracts., Anhê FF, Varin TV, Le Barz M, Desjardins Y, Levy E, Roy D, Marette A, Current obesity reports, 2015, 10.1007/s13679-015-0172-9
  • Probiotics as Complementary Treatment for Metabolic Disorders., Le Barz M, Anhê FF, Varin TV, Desjardins Y, Levy E, Roy D, Urdaci MC, Marette A, Diabetes & metabolism journal, 2015, 10.4093/dmj.2015.39.4.291
  • A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice., Anhê FF, Roy D, Pilon G, Dudonné S, Matamoros S, Varin TV, Garofalo C, Moine Q, Desjardins Y, Levy E, Marette A, Gut, 2014, 10.1136/gutjnl-2014-307142
  • Quercetin decreases inflammatory response and increases insulin action in skeletal muscle of ob/ob mice and in L6 myotubes., Anhê GF, Okamoto MM, Kinote A, Sollon C, Lellis-Santos C, Anhê FF, Lima GA, Hirabara SM, Velloso LA, Bordin S, Machado UF, European journal of pharmacology, 2012, 10.1016/j.ejphar.2012.06.007
  • Smad5 regulates Akt2 expression and insulin-induced glucose uptake in L6 myotubes., Anhê FF, Lellis-Santos C, Leite AR, Hirabara SM, Boschero AC, Curi R, Anhê GF, Bordin S, Molecular and cellular endocrinology, 2010, 10.1016/j.mce.2010.01.003
  • Postpartum glycemic homeostasis in early lactating rats is accompanied by transient and specific increase of soleus insulin response through IRS2/AKT pathway., Anhê GF, Hirabara SM, Turrer TC, Caperuto LC, Anhê FF, Ribeiro LM, Marçal AC, Carvalho CR, Curi R, Machado UF, Bordin S, American journal of physiology. Regulatory, integrative and comparative physiology, 2007, 10.1152/ajpregu.00902.2006

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