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Dimcho Bachvarov

Professeur titulaire

Dimcho Bachvarov
dimcho.bachvarov@fmed.ulaval.ca
Centre de recherche sur le cancer
Centre de recherche du CHU de Québec - Université Laval
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Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Médecine régénératrice et moléculaire
Oncologie

Domaines et intérêts de recherche du (de la) professeur(e) :

Cancer
  • Cancer de l'appareil reproducteur
  • Cancer héréditaire
  • Carcinogénèse
  • Chimiothérapie
  • Gène suppresseur
  • Oncogènes
  • Signalisation cellulaire et cancer
  • Thérapie cellulaire du cancer
Génomique et protéomique
  • Génotype et phénotype
  • Mécanismes biologiques et biochimiques
  • Protéomique fonctionnelle et structurale

Projets de recherche

  • (FRSQ 67140-CHUM) Axe banque de tissus et de données BTD / Réseau de recherche sur le cancer / projet "Tumeurs sein / ovaire 26380 - Fonds de recherche du Québec - Santé - Réseaux thématiques de recherche, chercheur principal - 2007-04-01 au 2021-09-30

Publications

  • Development of a 3D functional assay and identification of biomarkers, predictive for response of high-grade serous ovarian cancer (HGSOC) patients to poly-ADP ribose polymerase inhibitors (PARPis): targeted therapy, Razan Sheta, Magdalena Bachvarova, Marie Plante, Marie-Claude Renaud, Alexandra Sebastianelli, Jean Gregoire, Jamilet Miranda Navarro, Ricardo Bringas Perez, Jean-Yves Masson, Dimcho Bachvarov, Journal of Translational Medicine, 2020, 10.1186/s12967-020-02613-4
  • LY75 Ablation Mediates Mesenchymal-Epithelial Transition (MET) in Epithelial Ovarian Cancer (EOC) Cells Associated with DNA Methylation Alterations and Suppression of the Wnt/β-Catenin Pathway, Sadia Mehdi, Magdalena Bachvarova, Marie-Pier Scott-Boyer, Arnaud Droit, Dimcho Bachvarov, International Journal of Molecular Sciences, 2020, 10.3390/ijms21051848
  • Performance of preoperative plasma tumor markers HE4 and CA125 in predicting ovarian cancer mortality in women with epithelial ovarian cancer., Furrer D, Grégoire J, Turcotte S, Plante M, Bachvarov D, Trudel D, Têtu B, Douville P, Bairati I, PloS one, 2019, 10.1371/journal.pone.0218621
  • The polypeptide GALNT6 Displays Redundant Functions upon Suppression of its Closest Homolog GALNT3 in Mediating Aberrant O-Glycosylation, Associated with Ovarian Cancer Progression., Sheta R, Bachvarova M, Macdonald E, Gobeil S, Vanderhyden B, Bachvarov D, International journal of molecular sciences, 2019, 10.3390/ijms20092264
  • Proteases and their inhibitors as prognostic factors for high-grade serous ovarian cancer., Trudel D, Avarvarei LM, Orain M, Turcotte S, Plante M, Grégoire J, Kappelhoff R, Labbé DP, Bachvarov D, Têtu B, Overall CM, Bairati I, Pathology, research and practice, 2019, 10.1016/j.prp.2019.02.019
  • Proffered papers and posters presented at the Seventh International Symposium on Hereditary Breast and Ovarian Cancer—BRCA: From the Personal to the Population: Presented by the Hereditary Breast and Ovarian Cancer Foundation in collaboration with the Program in Cancer Genetics, McGill University; Centre Mont-Royal, Montreal, QC; 8–11 May 2018., , Current oncology (Toronto, Ont.), 2018, 10.3747/co.25.4243
  • Characteristics and outcome of the COEUR Canadian validation cohort for ovarian cancer biomarkers., Le Page C, Rahimi K, Köbel M, Tonin PN, Meunier L, Portelance L, Bernard M, Nelson BH, Bernardini MQ, Bartlett JMS, Bachvarov D, Gotlieb WH, Gilks B, Mes-Masson AM, BMC cancer, 2018, 10.1186/s12885-018-4242-8
  • Altered expression of different GalNAc‑transferases is associated with disease progression and poor prognosis in women with high-grade serous ovarian cancer., Sheta R, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Popa I, Bachvarov D, International journal of oncology, 2017, 10.3892/ijo.2017.4147
  • Hic-5 regulates epithelial to mesenchymal transition in ovarian cancer cells in a TGFβ1-independent manner., Sheta R, Wang ZQ, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Gobeil S, Morin C, Macdonald E, Vanderhyden B, Bachvarov D, Oncotarget, 2017, 10.18632/oncotarget.19714
  • Systems biology combining human- and animal-data miRNA and mRNA data identifies new targets in ureteropelvic junction obstruction., Papadopoulos T, Casemayou A, Neau E, Breuil B, Caubet C, Calise D, Thornhill BA, Bachvarova M, Belliere J, Chevalier RL, Moulos P, Bachvarov D, Klein J, BMC systems biology, 2017, 10.1186/s12918-017-0411-7
  • Biocompatible Lipid Nanoparticles as Carriers To Improve Curcumin Efficacy in Ovarian Cancer Treatment., Bondì ML, Emma MR, Botto C, Augello G, Azzolina A, Di Gaudio F, Craparo EF, Cavallaro G, Bachvarov D, Cervello M, Journal of agricultural and food chemistry, 2017, 10.1021/acs.jafc.6b04409
  • Suppression of the grainyhead transcription factor 2 gene (GRHL2) inhibits the proliferation, migration, invasion and mediates cell cycle arrest of ovarian cancer cells., Faddaoui A, Sheta R, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Gobeil S, Morin C, Ghani K, Bachvarov D, Cell cycle (Georgetown, Tex.), 2017, 10.1080/15384101.2017.1295181
  • NUPR1, a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance., Emma MR, Iovanna JL, Bachvarov D, Puleio R, Loria GR, Augello G, Candido S, Libra M, Gulino A, Cancila V, McCubrey JA, Montalto G, Cervello M, Cell Death & Disease, 2016, 10.1038/cddis.2016.175
  • Proteomic dataset for altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells., Sheta R, Roux-Dalvai F, Woo CM, Fournier F, Bourassa S, Bertozzi CR, Droit A, Bachvarov D, Data in Brief, 2016, 10.1016/j.dib.2016.05.060
  • A metabolic labeling approach for glycoproteomic analysis reveals altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells., Sheta R, Woo CM, Roux-Dalvai F, Fournier F, Bourassa S, Droit A, Bertozzi CR, Bachvarov D, Journal of proteomics, 2016, 10.1016/j.jprot.2016.04.009
  • The mannose receptor LY75 (DEC205/CD205) modulates cellular phenotype and metastatic potential of ovarian cancer cells., Faddaoui A, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Gobeil S, Morin C, Macdonald E, Vanderhyden B, Bachvarov D, Oncotarget, 2016, 10.18632/oncotarget.7288
  • BCAT1 expression associates with ovarian cancer progression: possible implications in altered disease metabolism., Wang ZQ, Faddaoui A, Bachvarova M, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Guillemette C, Gobeil S, Macdonald E, Vanderhyden B, Bachvarov D, Oncotarget, 2015, 10.18632/oncotarget.5159
  • Histone deacetylase 1 and 2 regulate Wnt and p53 pathways in the ureteric bud epithelium., Chen S, Yao X, Li Y, Saifudeen Z, Bachvarov D, El-Dahr SS, Development (Cambridge, England), 2015, 10.1242/dev.113506
  • Akt confers cisplatin chemoresistance in human gynecological carcinoma cells by modulating PPM1D stability., Ali AY, Kim JY, Pelletier JF, Vanderhyden BC, Bachvarov DR, Tsang BK, Molecular carcinogenesis, 2014, 10.1002/mc.22205
  • Genome-wide analysis of gestational gene-environment interactions in the developing kidney., Yan L, Yao X, Bachvarov D, Saifudeen Z, El-Dahr SS, Physiological genomics, 2014, 10.1152/physiolgenomics.00035.2014
  • Role of malignant ascites on human mesothelial cells and their gene expression profiles., Matte I, Lane D, Bachvarov D, Rancourt C, Piché A, BMC cancer, 2014, 10.1186/1471-2407-14-288
  • A 2-stage, single-arm, phase 2 study of epigallocatechin gallate-enriched green tea drink as a maintenance therapy in women with advanced-stage ovarian cancer, Trudel, D., Labbé, D.P., Araya-Farias, M., Doyen, A., Bazinet, L., Duchesne, T., Plante, M., Grégoire, J., Renaud, M.-C., Bachvarov, D., Têtu, B., Bairati, I., Obstetrical and Gynecological Survey, 2014, 10.1097/01.ogx.0000446909.04052.1e
  • A new paradigm for transcription factor TFIIB functionality., Gelev V, Zabolotny JM, Lange M, Hiromura M, Yoo SW, Orlando JS, Kushnir A, Horikoshi N, Paquet E, Bachvarov D, Schaffer PA, Usheva A, Scientific reports, 2014, 10.1038/srep03664
  • Role of aberrant glycosylation in ovarian cancer dissemination, Sheta, R., Bachvarov, D., Biomedical Reviews, 2014, 10.14748/bmr.v25.1050
  • Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation., Wang ZQ, Bachvarova M, Morin C, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Bachvarov D, Oncotarget, 2014, 10.18632/oncotarget.1652
  • Inhibition of RUNX2 transcriptional activity blocks the proliferation, migration and invasion of epithelial ovarian carcinoma cells., Wang ZQ, Keita M, Bachvarova M, Gobeil S, Morin C, Plante M, Gregoire J, Renaud MC, Sebastianelli A, Trinh XB, Bachvarov D, PloS one, 2013, 10.1371/journal.pone.0074384
  • Genome-wide analysis of the p53 gene regulatory network in the developing mouse kidney., Li Y, Liu J, McLaughlin N, Bachvarov D, Saifudeen Z, El-Dahr SS, Physiological genomics, 2013, 10.1152/physiolgenomics.00113.2013
  • A two-stage, single-arm, phase II study of EGCG-enriched green tea drink as a maintenance therapy in women with advanced stage ovarian cancer., Trudel D, Labbé DP, Araya-Farias M, Doyen A, Bazinet L, Duchesne T, Plante M, Grégoire J, Renaud MC, Bachvarov D, Têtu B, Bairati I, Gynecologic oncology, 2013, 10.1016/j.ygyno.2013.08.019
  • Novel combination of sorafenib and celecoxib provides synergistic anti-proliferative and pro-apoptotic effects in human liver cancer cells., Cervello M, Bachvarov D, Lampiasi N, Cusimano A, Azzolina A, McCubrey JA, Montalto G, PloS one, 2013, 10.1371/journal.pone.0065569
  • Erratum: Biopreserv Biobank 11:83-93 (Biopreservation and Biobanking (2013) 11 (83-93)), Le Page, C., Köbel, M., De Ladurantaye, M., Rahimi, K., Madore, J., Babinszky, S., Bachvarov, D.R., Bachvarova, M., Beauchamp, M.-C., Cass, C.E., Chadwick, D., Colleen, C., Damaraju, S., Dufour, J., Gotlieb, W.H., Kalloger, S.E., Portelance, L., McAlpine, J.N., Matte, I., Piché, A., Shaw, P., Roehrl, M.H.A., Vanderhyden, B.C., Watson, P.H., Huntsman, D.G., Provencher, D.M., Mes-Masson, A.-M., Biopreservation and Biobanking, 2013, 10.1089/bio.2013.1149
  • Global methylation profiling in serous ovarian cancer is indicative for distinct aberrant DNA methylation signatures associated with tumor aggressiveness and disease progression, Keita, M., Wang, Z.-Q., Pelletier, J.-F., Bachvarova, M., Plante, M., Gregoire, J., Renaud, M.-C., Mes-Masson, A.-M., Paquet, É.R., Bachvarov, D., Gynecologic Oncology, 2013, 10.1016/j.ygyno.2012.11.036
  • Next-generation biobanking of metastases to enable multidimensional molecular profiling in personalized medicine, Diaz, Z., Aguilar-Mahecha, A., Paquet, E.R., Basik, M., Orain, M., Camlioglu, E., Constantin, A., Benlimame, N., Bachvarov, D., Jannot, G., Simard, M.J., Chabot, B., Gologan, A., Klinck, R., Gagnon-Kugler, T., Lespérance, B., Samson, B., Kavan, P., Alcindor, T., Dalfen, R., Lan, C., Chabot, C., Buchanan, M., Przybytkowrski, E., Qureshi, S., Rousseau, C., Spatz, A., Têtu, B., Batist, G., Modern Pathology, 2013, 10.1038/modpathol.2013.81
  • Specimen quality evaluation in canadian biobanks participating in the COEUR repository, Le Page, C., Köbel, M., De Ladurantaye, M., Rahimi, K., Madore, J., Babinszky, S., Bachvarov, D.R., Bachvarova, M., Beauchamp, M.-C., Cass, C.E., Chadwick, D., Colleen, C., Damaraju, S., Dufour, J., Gotlieb, W.H., Kalloger, S.E., Portelance, L., McAlpine, J.N., Matte, I., Piché, A., Shaw, P., Vanderhyden, B.C., Watson, P.H., Huntsman, D.G., Provencher, D.M., Mes-Masson, A.-M., Biopreservation and Biobanking, 2013, 10.1089/bio.2012.0044
  • The RUNX1 transcription factor is expressed in serous epithelial ovarian carcinoma and contributes to cell proliferation, migration and invasion, Keita, M., Bachvarova, M., Morin, C., Plante, M., Gregoire, J., Renaud, M.-C., Sebastianelli, A., Trinh, X.B., Bachvarov, D., Cell Cycle, 2013, 10.4161/cc.23963
  • A novel genome-based approach correlates TMPRSS3 overexpression in ovarian cancer with DNA hypomethylation, Guerrero, K., Wang, Z., Bachvarova, M., Gregoire, J., Renaud, M.-C., Plante, M., Bachvarov, D., Gynecologic Oncology, 2012, 10.1016/j.ygyno.2012.03.026
  • Human epididymis protein 4 (HE4) and ovarian cancer prognosis, Trudel, D., Têtu, B., Grégoire, J., Plante, M., Renaud, M.-C., Bachvarov, D., Douville, P., Bairati, I., Gynecologic Oncology, 2012, 10.1016/j.ygyno.2012.09.003
  • Molecular mechanisms of sorafenib action in liver cancer cells, Cervello, M., Bachvarov, D., Lampiasi, N., Cusimano, A., Azzolina, A., McCubrey, J.A., Montalto, G., Cell Cycle, 2012, 10.4161/cc.21193
  • Characterization of DOK1, a candidate tumor suppressor gene, in epithelial ovarian cancer, Mercier, P.-L., Bachvarova, M., Plante, M., Gregoire, J., Renaud, M.-C., Ghani, K., Têtu, B., Bairati, I., Bachvarov, D., Molecular Oncology, 2011, 10.1016/j.molonc.2011.07.003
  • COX-2-dependent and COX-2-independent mode of action of celecoxib in human liver cancer cells, Cervello, M., Bachvarov, D., Cusimano, A., Sardina, F., Azzolina, A., Lampiasi, N., Giannitrapani, L., McCubrey, J.A., Montalto, G., OMICS A Journal of Integrative Biology, 2011, 10.1089/omi.2010.0092
  • Erratum: Cytotoxic effect of the bradykinin antagonist BKM570 in ovarian cancer cells: Analysis of the molecular mechanisms of its anti-proliferative action (FEBS Journal (2010) 277 (5146-5160)), Jutras, S., Bachvarova, M., Keita, M., Bascands, J.-L., Mes-Masson, A.M., Stewart, J.M., Bachvarov, D., FEBS Journal, 2011, 10.1111/j.1742-4658.2011.08024.x
  • Histone deacetylase (HDAC) activity is critical for embryonic kidney gene expression, growth, and differentiation, Chen, S., Bellew, C., Yao, X., Stefkova, J., Dipp, S., Saifudeen, Z., Bachvarov, D., El-Dahr, S.S., Journal of Biological Chemistry, 2011, 10.1074/jbc.M111.248278
  • Microarray-Based oncogenic pathway profiling in advanced serous papillary ovarian carcinoma, Trinh, X.B., Tjalma, W.A.A., Dirix, L.Y., Vermeulen, P.B., Peeters, D.J., Bachvarov, D., Plante, M., Berns, E.M., Helleman, J., van Laere, S.J., van Dam, P.A., PLoS ONE, 2011, 10.1371/journal.pone.0022469
  • Novel combination of celecoxib and proteasome inhibitor MG132 provides synergistic antiproliferative and proapoptotic effects in human liver tumor cells, Cusimano, A., Azzolina, A., Iovanna, J.L., Bachvarov, D., McCubrey, J.A., D'Alessandro, N., Montalto, G., Cervello, M., Cell Cycle, 2010, 10.4161/cc.9.7.11254
  • Strong cytotoxic effect of the bradykinin antagonist BKM-570 in ovarian cancer cells - Analysis of the molecular mechanisms of its antiproliferative action, Jutras, S., Bachvarova, M., Keita, M., Bascands, J.-L., Mes-Masson, A.-M., Stewart, J.M., Bachvarov, D., FEBS Journal, 2010, 10.1111/j.1742-4658.2010.07928.x
  • Molecular determinants of LPS-induced acute renal inflammation: Implication of the kinin B1 receptor, Bascands, J.-L., Bachvarova, M., Neau, E., Schanstra, J.P., Bachvarov, D., Biochemical and Biophysical Research Communications, 2009, 10.1016/j.bbrc.2009.06.063
  • Novel nanostructured carbon materials for supercapacitors in integrated energy storage systems, Mladenov, M., Raicheff, R., Petrov, N., Kovacheva, D., Nickolov, R., Trenev, V., Bachvarov, D., Belov, K., International Conferences on Multi-Material Micro Manufacture, 4M/International Conferences on Micro Manufacturing, ICOMM, 2009, 10.1243/17547164C0012009043
  • Global gene expression analysis of early response to chemotherapy treatment in ovarian cancer spheroids, L'Espérance, S., Bachvarova, M., Tetu, B., Mes-Masson, A.-M., Bachvarov, D., BMC Genomics, 2008, 10.1186/1471-2164-9-99
  • Immunohistochemical analysis of possible chemoresistance markers identified by micro-arrays on serous ovarian carcinomas, Têtu, B., Popa, I., Bairati, I., L'Esperance, S., Bachvarova, M., Plante, M., Harel, F., Bachvarov, D., Modern Pathology, 2008, 10.1038/modpathol.2008.80
  • Immunohistochemical profiling of benign, low malignant potential and low grade serous epithelial ovarian tumors, Ouellet, V., Ling, T.H., Normandin, K., Madore, J., Lussier, C., Barrès, V., Bachvarov, D., Rancourt, C., Tonin, P.N., Provencher, D.M., Mes-Masson, A.-M., BMC Cancer, 2008, 10.1186/1471-2407-8-346
  • The strand separation and nuclease activities associated with YB-1 are dispensable for cisplatin resistance but overexpression of YB-1 in MCF7 and MDA-MB-231 breast tumor cells generates several chemoresistance signatures, Guay, D., Evoy, A.-A., Paquet, E., Garand, C., Bachvarova, M., Bachvarov, D., Lebel, M., International Journal of Biochemistry and Cell Biology, 2008, 10.1016/j.biocel.2008.04.011
  • Gene expression profiling in the remnant kidney model of wild type and kinin B1 and B2 receptor knockout mice, Schanstra, J.P., Bachvarova, M., Neau, E., Bascands, J.L., Bachvarov, D., Kidney International, 2007, 10.1038/sj.ki.5002172
  • Gene expression patterns of chemoresistant and chemosensitive serous epithelial ovarian tumors with possible predictive value in response to initial chemotherapy, Bachvarov, D., L'Esperance, S., Popa, I., Bachvarova, M., Plante, M., Têtu, B., International Journal of Oncology, 2006
  • Gene expression profiling of paired ovarian tumors obtained prior to and following adjuvant chemotherapy: Molecular signatures of chemoresistant tumors, L'Espérance, S., Popa, I., Bachvarova, M., Plante, M., Patten, N., Wu, L., Têtu, B., Bachvarov, D., International Journal of Oncology, 2006
  • Genes invoked in the ovarian transition to menopause, Zimon, A., Erat, A., Von Wald, T., Bissell, B., Koulova, A., Choi, C.H., Bachvarov, D., Reindollar, R.H., Usheva, A., Nucleic Acids Research, 2006, 10.1093/nar/gkl387
  • Renal gene expression profiling using kinin B1 and B2 receptor knockout mice reveals comparable modulation of functionally related genes, Bachvarov, D., Bachvarova, M., Koumangaye, R., Klein, J., Pesquero, J.B., Neau, E., Bader, M., Schanstra, J.P., Bascands, J.L., Biological Chemistry, 2006, 10.1515/BC.2006.004
  • In vivo DNase I-mediated footprinting analysis along the human bradykinin B1 receptor (BDKRB1) gene promoter: Evidence for cell-specific regulation, Angers, M., Drouin, R., Bachvarova, M., Paradis, I., Bissell, B., Hiromura, M., Usheva, A., Bachvarov, D., Biochemical Journal, 2005, 10.1042/BJ20042104
  • Characterization of a fluorescent conjugate of the rabbit angiotensin AT 1 receptor, Fortin, J.-P., Bouthillier, J., Bastien, L., Bachvarov, D.R., Marceau, F., British Journal of Pharmacology, 2003, 10.1038/sj.bjp.0705176
  • YY1 is regulated by O-linked N-acetylglucosaminylation (O-GlcNAcylation), Hiromura, M., Choi, C.H., Sabourin, N.A., Jones, H., Bachvarov, D., Usheva, A., Journal of Biological Chemistry, 2003, 10.1074/jbc.M300789200
  • Agonist-induced translocation of the kinin B1 receptor to caveolae-related rafts, Sabourin, T., Bastien, L., Bachvarov, D.R., Marceau, F., Molecular Pharmacology, 2002, 10.1124/mol.61.3.546
  • Bradykinin B 2 receptor gene polymorphism is associated with altered urinary albumin/creatinine values in diabetic patients 1, Maltais, I., Bachvarova, M., Maheux, P., Perron, P., Marceau, F., Bachvarov, D., Canadian Journal of Physiology and Pharmacology, 2002, 10.1139/y02-036
  • Effects of captopril and omapatrilat on early post-myocardial infarction survival and cardiac hemodynamics in rats: Interaction with cardiac cytokine expression, Blais Jr., C., Lapointe, N., Rouleau, J.-L., Clément, R., Bachvarov, D.R., Adam, A., Canadian Journal of Physiology and Pharmacology, 2002, 10.1139/y01-096
  • Identification of two genes differentially expressed upon different spatial configuration of the MGH-U3 human bladder cancer cells, Champetier, S., Fradet, Y., Bachvarov, D., Urologic Oncology, 2002, 10.1016/S1078-1439(01)00130-2
  • Absence of ligand-induced regulation of kinin receptor expression in the rabbit, Sabourin, T., Guay, K., Houle, S., Bouthillier, J., Bachvarov, D.R., Adam, A., Marceau, F., British Journal of Pharmacology, 2001, 10.1038/sj.bjp.0704158
  • Bradykinin B2 receptor endocytosis, recycling, and down-regulation assessed using green fluorescent protein conjugates, Bachvarov, D.R., Houle, S., Bachvarova, M., Bouthillier, J., Adam, A., Marceau, F., Journal of Pharmacology and Experimental Therapeutics, 2001
  • Ligand-mediated regulation of kinin receptors in the rabbit, Marceau, F., Adam, A., Houle, S., Bouthillier, J., Bachvarova, M., Bachvarov, D.R., Biological Chemistry, 2001, 10.1515/BC.2001.019
  • Altered frequency of a promoter polymorphism of the kinin B2 receptor gene in hypertensive African-Americans, Gainer, J.V., Brown, N.J., Bachvarova, M., Bastien, L., Maltais, I., Marceau, F., Bachvarov, D.R., American Journal of Hypertension, 2000, 10.1016/S0895-7061(00)01215-2
  • Antagonist-induced intracellular sequestration of rabbit bradykinin B2 receptor, Houle, S., Larrivée, J.-F., Bachvarova, M., Bouthillier, J., Bachvarov, D.R., Marceau, F., Hypertension, 2000, 10.1161/01.HYP.35.6.1319
  • Effect of allelic polymorphism of the B1 and B2 receptor genes on the contractile responses of the human umbilical vein to kinins, Houle, S., Landry, M., Audet, R., Bouthillier, J., Bachvarov, D.R., Marceau, F., Journal of Pharmacology and Experimental Therapeutics, 2000
  • In vivo protein-DNA interactions at the kinin B1 receptor gene promoter: No modification on interleukin-1 beta or lipopolysaccharide induction, Angers, M., Drouin, R., Bachvarova, M., Paradis, I., Marceau, F., Bachvarov, D.R., Journal of Cellular Biochemistry, 2000, 10.1002/(SICI)1097-4644(20000801)78:2<278::AID-JCB10>3.0.CO;2-F
  • Inflammatory hyperalgesia induced by zymosan in the plantar tissue of the rat: effect of kinin receptor antagonists, Bélichard, P., Landry, M., Faye, P., Bachvarov, D.R., Bouthillier, J., Pruneau, D., Marceau, F., Immunopharmacology, 2000, 10.1016/S0162-3109(99)00165-4
  • Non-competitive pharmacological antagonism at the rabbit B 1 receptor, Larrivée, J.-F., Gera, L., Houle, S., Bouthillier, J., Bachvarov, D.R., Stewart, J.M., Marceau, F., British Journal of Pharmacology, 2000, 10.1038/sj.bjp.0703656
  • Characterization of a polymorphism in the coding region of the human C5a anaphylatoxin receptor, Marceau, F., Bachvarova, M., Bergeron, J., Bachvarov, D.R., Immunogenetics, 1999, 10.1007/s002510050657
  • Cloning and preliminary pharmacological characterization of the anaphylatoxin C5a receptor in the rabbit, Bachvarov, D.R., Houle, S., Bachvarova, M., Bouthillier, J., St-Pierre, S.A., Fukuoka, Y., Ember, J.A., Marceau, F., British Journal of Pharmacology, 1999, 10.1038/sj.bjp.0702812
  • Effect of endogenous kinins, prostanoids, and NO on kinin B1 and B2 receptor expression in the rabbit, Marceau, F., Larrivée, J.-F., Bouthillier, J., Bachvarova, M., Houle, S., Bachvarov, D.R., American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 1999
  • Altered frequency of a promoter polymorphic allele of the kinin β 1 receptor gene in inflammatory bowel disease, Bachvarov, D.R., Landry, M., Houle, S., Pare, P., Marceau, F., Gastroenterology, 1998, 10.1016/S0016-5085(98)70071-X
  • Characterization of two polymorphic sites in the human kinin B1 receptor gene: Altered frequency of an allele in patients with a history of end-stage renal failure, Bachvarov, D.R., Landry, M., Pelletier, I., Chevrette, M., Betard, C., Houde, I., Bergeron, J., Lebel, M., Marceau, F., Journal of the American Society of Nephrology, 1998
  • Interleukin 8 (IL-8) induces the expression of kinin B1 receptor in human lung fibroblasts, Bastian, S., Paquet, J.-L., Robert, C., Cremers, B., Loillier, B., Larrivée, J.-F., Bachvarov, D.R., Marceau, F., Pruneau, D., Biochemical and Biophysical Research Communications, 1998, 10.1006/bbrc.1998.9848
  • Kinin receptors, Marceau, F., Bachvarov, D.R., Clinical Reviews in Allergy and Immunology, 1998, 10.1007/BF02737658
  • Role of the mitogen-activated protein kinases in the expression of the kinin B1receptors induced by tissue injury, Larrivée, J.-F., Bachvarov, D.R., Houle, F., Landry, J., Huot, J., Marceau, F., Journal of Immunology, 1998
  • The B1 receptors for kinins, Marceau, F., Hess, J.F., Bachvarov, D.R., Pharmacological Reviews, 1998
  • Structural and functional characterization of the human b1 kinin receptor promoter, Bachvarov, D., Larrivee, J.-F., Bachvaroya, M., Angers, M., Drouin, R., Marceau, F., FASEB Journal, 1997
  • The kinin B1 receptor: An inducible G protein coupled receptor, Marceau, F., Larrivée, J.-F., Saint-Jacques, E., Bachvarov, D.R., Canadian Journal of Physiology and Pharmacology, 1997, 10.1139/cjpp-75-6-725
  • Structure and genomic organization of the human B1 receptor gene for kinins (BDKRB1), Bachvarov, D.R., Hess, J.F., Menke, J.G., Larrivée, J.-F., Marceau, F., Genomics, 1996, 10.1006/geno.1996.0213
  • Cloning and pharmacological characterization of the rabbit bradykinin B 2 receptor, Bachvarov, D.R., Saint-Jacques, E., Larrivee, J.-F., Levesque, L., Rioux, F., Drapeau, G., Marceau, F., Journal of Pharmacology and Experimental Therapeutics, 1995
  • Regulation of kinin‐induced contraction and DNA synthesis by inflammatory cytokines in the smooth muscle of the rabbit aorta, Levesque, L., Larrivée, J.‐F., Bachvarov, D.R., Rioux, F., Drapeau, G., Marceau, F., British Journal of Pharmacology, 1995, 10.1111/j.1476-5381.1995.tb16390.x
  • Mapping of a Sequence Essential for the Nuclear Transport of the Xenopus Ribosomal Transcription Factor xUBF Using a Simple Coupled Translation-Transport and Acid Extraction Approach, Dimitrov, S.I., Bachvarov, D., Moss, T., DNA and Cell Biology, 1993, 10.1089/dna.1993.12.275
  • Structure of human type II 5 alpha-reductase gene., , Endocrinology, 1992, 10.1210/endo.131.3.1505484
  • Heterogeneity in the Xenopus ribosomal transcription factor xUBF has a molecular basis distinct from that in mammals., , FEBS letters, 1991, 10.1016/0014-5793(91)81002-p
  • Detection of human papillomavirus DNA in gynaecological swabs by filter in situ hybridization., , Acta virologica, 1991
  • The RNA polymerase I transcription factor xUBF contains 5 tandemly repeated HMG homology boxes., , Nucleic acids research, 1991, 10.1093/nar/19.9.2331
  • Detection of human papillomavirus DNA in gynaecological swabs by filter in situ hybridization., Mincheva, A., Shindarov, L., Karageosov, I., Slavchev, B., Bachvarov, D., Vasilev, N., Makaveeva, V., Acta virologica, 1991
  • Construction of a Co1E1 plasmid bearing inducible high-copy-number phenotype., , Folia microbiologica, 1990, 10.1007/bf02820482
  • Constitutive expression of a native human interferon-alpha 1 gene in Escherichia coli., , The International journal of biochemistry, 1989, 10.1016/0020-711x(89)90230-9
  • Determination of plasmid copy number by the "boiling" method., , Analytical biochemistry, 1987, 10.1016/0003-2697(87)90211-9
  • Sequence heterogeneity of the human alphoid satellite DNA and thermal stability of mismatched alphoid DNA duplexes., , The International journal of biochemistry, 1987, 10.1016/0020-711x(87)90179-0
  • Does the concentration of DNA (Co) and the time of incubation (t) as parameters of Cot influence the thermal stability of the DNA duplexes?, , Molecular biology reports, 1984, 10.1007/bf00775351
  • Large scale purification of plasmid DNA., , Preparative biochemistry, 1983, 10.1080/00327488308068745

Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2009
  • Sabina Cisa Wieczorek - Doctorat - En cours
  • Elias Acaf - Doctorat - En cours
  • Rosette Joseph - Maîtrise avec mémoire - 2013/05
  • Mamadou Keita - Doctorat - 2013/09
  • Jean-François Pelletier - Maîtrise avec mémoire - 2014/01
  • Zhi Qiang Wang - Doctorat - 2014/05
  • Razan Sheta - Doctorat - 2018/01
  • Sadia Mehdi - Doctorat - 2020/09

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