Denis R. Joanisse
Directeur de département
Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec
Contribution à la recherche
Axe de recherche de l'Université Laval :
Santé et bien-être durables
Thématiques de recherche de la Faculté de médecine :
Santé cardiovasculaire, respiratoire et métabolisme
Santé des populations et pratiques optimales en santé
Domaines et intérêts de recherche du (de la) professeur(e) :
Nutrition et métabolisme
- Désordres métaboliques
- Diabète
- Maladies lipidiques
- Maladies métaboliques
- Métabolisme
- Obésité
Génomique et protéomique
- Mécanismes biologiques et biochimiques
Projets de recherche
- 26ème congrès de l’Association québécoise des sciences de l’activité physique (AQSAP 2021) - Fonds de recherche du Québec - Santé - Réseaux thématiques de recherche, chercheur principal - 2021-04-01 au 2022-03-31
- Conférence grand public du Dr Claude Bouchard – L’histoire de la recherche au PEPS de l’Université Laval - Fonds de recherche du Québec - Santé - Réseaux thématiques de recherche, chercheur principal - 2021-04-01 au 2022-03-31
- Le préconditionnement ischémique pour optimiser la récupération de l’athlète - Institut national du sport du Québec, co-chercheur - 2018-09-01 au 2021-03-31
...
Publications
- Fitness, adiposopathy, and adiposity are independent predictors of insulin sensitivity in middle-aged men without diabetes, Huth, C., Pigeon, É., Riou, M.-È., St-Onge, J., Arguin, H., Couillard, E., Dubois, M.-J., Marette, A., Tremblay, A., Weisnagel, S.J., Lacaille, M., Mauriège, P., Joanisse, D.R., Journal of Physiology and Biochemistry, 2016, 10.1007/s13105-016-0488-2
- G0/G1 Switch Gene 2 controls adipose triglyceride lipase activity and lipid metabolism in skeletal muscle, Laurens, C., Badin, P.-M., Louche, K., Mairal, A., Tavernier, G., Marette, A., Tremblay, A., Weisnagel, S.J., Joanisse, D.R., Langin, D., Bourlier, V., Moro, C., Molecular Metabolism, 2016, 10.1016/j.molmet.2016.04.004
- [Statin intolerance and associated muscular dysfunctions]., Boulanger-Piette A, Bergeron J, Desgreniers J, Côté-Levesque M, Brassard D, Joanisse DR, Frenette J, 2015, 10.1051/medsci/20153112014
- Defective Natriuretic Peptide Receptor Signaling in Skeletal Muscle Links Obesity to Type 2 Diabetes., Coué M, Badin PM, Vila IK, Laurens C, Louche K, Marquès MA, Bourlier V, Mouisel E, Tavernier G, Rustan AC, Galgani JE, Joanisse DR, Smith SR, Langin D, Moro C, 2015, 10.2337/db15-0305
- Gene expression of different adipose tissues of severely obese women with or without a dysmetabolic profile., Mauriège P, Joanisse DR, CasparBauguil S, Cartier A, Lemieux I, Bergeron J, Biron S, Marceau P, Richard D, 2015, 10.1007/s13105-015-0436-6
- Irisin is more strongly predicted by muscle oxidative potential than adiposity in non-diabetic men., Huth C, Dubois MJ, Marette A, Tremblay A, Weisnagel SJ, Lacaille M, Mauriège P, Joanisse DR, 2015, 10.1007/s13105-015-0402-3
- Anthropometric characteristics account for time to exhaustion in cycling., Basset FA, Billaut F, Joanisse DR, 2014, 10.1055/s-0034-1375694
- Mitochondrial dysregulation in the pathogenesis of diabetes: potential for mitochondrial biogenesis-mediated interventions., Joseph AM, Joanisse DR, Baillot RG, Hood DA, 2012, 10.1155/2012/642038
- Effects of weight loss and leptin on skeletal muscle in human subjects., Baldwin KM, Joanisse DR, Haddad F, Goldsmith RL, Gallagher D, Pavlovich KH, Shamoon EL, Leibel RL, Rosenbaum M, 2011, 10.1152/ajpregu.00397.2011
- Cardioprotective effects of glucose and insulin administration while maintaining normoglycemia (GIN therapy) in patients undergoing coronary artery bypass grafting., Carvalho G, Pelletier P, Albacker T, Lachapelle K, Joanisse DR, Hatzakorzian R, Lattermann R, Sato H, Marette A, Schricker T, 2011, 10.1210/jc.2010-1934
- Milk supplementation facilitates appetite control in obese women during weight loss: a randomised, single-blind, placebo-controlled trial., Gilbert JA, Joanisse DR, Chaput JP, Miegueu P, Cianflone K, Alméras N, Tremblay A, 2011, 10.1017/S0007114510003119
- Atrophy and hypertrophy signalling of the quadriceps and diaphragm in COPD., Doucet M, Dubé A, Joanisse DR, Debigaré R, Michaud A, Paré MÈ, Vaillancourt R, Fréchette E, Maltais F, 2010, 10.1136/thx.2009.133827
- Effects of experimental weight perturbation on skeletal muscle work efficiency, fuel utilization, and biochemistry in human subjects., Goldsmith R, Joanisse DR, Gallagher D, Pavlovich K, Shamoon E, Leibel RL, Rosenbaum M, 2010, 10.1152/ajpregu.00053.2009
- Validation of a simple index (SIisOGTT) of insulin sensitivity in a population of sedentary men., Pigeon E, Riou ME, St-Onge J, Couillard E, Tremblay A, Marette A, Weisnagel SJ, Joanisse DR, 2009, 10.1016/j.diabet.2009.04.007
- Recent evolution in demographic and clinical characteristics and in-hospital morbidity in patients undergoing coronary surgery., Baillot RG, Joanisse DR, Stevens LM, Doyle DP, Dionne B, Lellouche F, 2009
- Predictors of cardiovascular fitness in sedentary men., Riou ME, Pigeon E, St-Onge J, Tremblay A, Marette A, Weisnagel SJ, Joanisse DR, 2009, 10.1139/H08-144
- Reduction of type IIb myosin and IIB fibers in tibialis anterior muscle of mini-muscle mice from high-activity lines., Bilodeau GM, Guderley H, Joanisse DR, Garland T Jr, 2009, 10.1002/jez.518
- Cardiorespiratory fitness and components of the metabolic syndrome in sedentary men., Riou ME, Pigeon E, St-Onge J, Tremblay A, Marette A, Weisnagel J, Joanisse DR, 2009, 10.1159/000232586
- Recent evolution in demographic and clinical characteristics and in-hospital morbidity in patients undergoing coronary surgery, Baillot, R.G., Joanisse, D.R., Stevens, L.M., Doyle, D.P., Dionne, B., Lellouche, F., Canadian Journal of Surgery, 2009
- Shift in metabolic fuel in acylation-stimulating protein-deficient mice following a high-fat diet., Roy C, Paglialunga S, Fisette A, Schrauwen P, Moonen-Kornips E, St-Onge J, Hesselink MK, Richard D, Joanisse DR, Cianflone K, 2008, 10.1152/ajpendo.00689.2007
- Altered fibre types in gastrocnemius muscle of high wheel-running selected mice with mini-muscle phenotypes., Guderley H, Joanisse DR, Mokas S, Bilodeau GM, Garland T Jr, 2008, 10.1016/j.cbpb.2007.11.012
- Effect of weight loss on lactate transporter expression in skeletal muscle of obese subjects., Metz L, Mercier J, Tremblay A, Alméras N, Joanisse DR, 2008, 10.1152/japplphysiol.00681.2007
- Increased fat accumulation in liver may link insulin resistance with subcutaneous abdominal adipocyte enlargement, visceral adiposity, and hypoadiponectinemia in obese individuals., Koska J, Stefan N, Permana PA, Weyer C, Sonoda M, Bogardus C, Smith SR, Joanisse DR, Funahashi T, Krakoff J, Bunt JC, 2008
- From the authors [4], Doucet, M., Russell, A., Joanisse, D.R., Maltais, F., American Journal of Respiratory and Critical Care Medicine, 2008
- Increased fat accumulation in liver may link insulin resistance with subcutaneous abdominal adipocyte enlargement, visceral adiposity, and hypoadiponectinemia in obese individuals, Koska, J., Stefan, N., Permana, P.A., Weyer, C., Sonoda, M., Bogardus, C., Smith, S.R., Joanisse, D.R., Funahashi, T., Krakoff, J., Bunt, J.C., American Journal of Clinical Nutrition, 2008
- Mid-thigh subcutaneous adipose tissue and glucose tolerance in the Quebec family study., Pigeon E, Couillard E, Tremblay A, Bouchard C, Weisnagel SJ, Joanisse DR, 2008, 10.1159/000177047
- Muscle Atrophy and Hypertrophy Signaling Pathways in COPD: A Role in Muscle Remodeling?, Mariève Doucet, Aaron Russell, Denis R. Joanisse, François Maltais, Am J Respir Crit Care Med, 2008, 10.1164/ajrccm.177.1.122a
- Substrate utilization in women with obesity and type 2 diabetes: Effects of exercise and nutritional adaptation, Metz, L., Lambert, K., Joanisse, D., Progress in Exercise and Women's Health Research, 2008
- 11beta-HSD1 inhibition improves triglyceridemia through reduced liver VLDL secretion and partitions lipids toward oxidative tissues., Berthiaume M, Laplante M, Festuccia WT, Cianflone K, Turcotte LP, Joanisse DR, Olivecrona G, Thieringer R, Deshaies Y, 2007, 10.1152/ajpendo.00276.2007
- Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease., Doucet M, Russell AP, Léger B, Debigaré R, Joanisse DR, Caron MA, LeBlanc P, Maltais F, 2007, 10.1164/rccm.200605-704OC
- Depot-specific modulation of rat intraabdominal adipose tissue lipid metabolism by pharmacological inhibition of 11beta-hydroxysteroid dehydrogenase type 1., Berthiaume M, Laplante M, Festuccia W, Gélinas Y, Poulin S, Lalonde J, Joanisse DR, Thieringer R, Deshaies Y, 2007, 10.1210/en.2006-1199
- Muscle adiposity and body fat distribution in type 1 and type 2 diabetes: varying relationships according to diabetes type., Dubé MC, Joanisse DR, Prud'homme D, Lemieux S, Bouchard C, Pérusse L, Lavoie C, Weisnagel SJ, 2006, 10.1038/sj.ijo.0803337
- Effects of short-term normobaric hypoxia on haematology, muscle phenotypes and physical performance in highly trained athletes., Basset FA, Joanisse DR, Boivin F, St-Onge J, Billaut F, Doré J, Chouinard R, Falgairette G, Richard D, Boulay MR, 2006, 10.1113/expphysiol.2005.031682
- Inverse relationship between exercise economy and oxidative capacity in muscle., Hunter GR, Bamman MM, Larson-Meyer DE, Joanisse DR, McCarthy JP, Blaudeau TE, Newcomer BR, 2005, 10.1007/s00421-005-1370-z
- Calcium intake, body composition and plasma lipid-lipoprotein concentrations in adults., Tremblay A, Joanisse DR, 2005
- Calcium intake, body composition and plasma lipid-lipoprotein concentrations in adults, Tremblay, A., Joanisse, D.R., Australian Journal of Dairy Technology, 2005
- Skeletal Muscle Metabolism and Plasticity, Denis R. Joanisse, Functional Metabolism, 2005, 10.1002/047167558x.ch11
- Adaptation of the diaphragm and the vastus lateralis in mild-to-moderate COPD., Doucet M, Debigaré R, Joanisse DR, Côté C, Leblanc P, Grégoire J, Deslauriers J, Vaillancourt R, Maltais F, 2004, 10.1183/09031936.04.00020204
- Effects of intense and prolonged exercise on insulin sensitivity and glycogen metabolism in hypertensive subjects., Rhéaume C, Waib PH, Kouamé N, Nadeau A, Lacourcière Y, Joanisse DR, Simoneau JA, Cléroux J, 2003, 10.1161/01.CIR.0000097112.25429.FB
- Skeletal muscle enzymes as predictors of 24-h energy metabolism in reduced-obese persons., Doucet E, Tremblay A, Simoneau JA, Joanisse DR, 2003
- Familial resemblance for muscle phenotypes in the HERITAGE Family Study., Rico-Sanz J, Rankinen T, Joanisse DR, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C, HERITAGE Family Study, 2003, 10.1249/01.MSS.0000079031.22755.63
- Associations between cardiorespiratory responses to exercise and the C34T AMPD1 gene polymorphism in the HERITAGE Family Study., Rico-Sanz J, Rankinen T, Joanisse DR, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C, HERITAGE Family study, 2003, 10.1152/physiolgenomics.00165.2002
- Effects of experimental weight perturbation on skeletal muscle work efficiency in human subjects., Rosenbaum M, Vandenborne K, Goldsmith R, Simoneau JA, Heymsfield S, Joanisse DR, Hirsch J, Murphy E, Matthews D, Segal KR, Leibel RL, 2003, 10.1152/ajpregu.00474.2002
- Na+-K+-ATPase alpha 2-gene and skeletal muscle characteristics in response to long-term overfeeding., Ukkola O, Joanisse DR, Tremblay A, Bouchard C, 2003, 10.1152/japplphysiol.00942.2002
- Associations between cardiorespiratory responses to exercise and the C34T AMPD1 gene polymorphism in the HERITAGE Family study, Rico-Sanz, J., Rankinen, T., Joanisse, D.R., Leon, A.S., Skinner, J.S., Wilmore, J.H., Rao, D.C., Bouchard, C., Physiological Genomics, 2003
- Effects of experimental weight perturbation on skeletal muscle work efficiency in human subjects, Rosenbaum, M., Vandenborne, K., Goldsmith, R., Simoneau, J.-A., Heymsfield, S., Joanisse, D.R., Hirsch, J., Murphy, E., Matthews, D., Segal, K.R., Leibel, R.L., American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 2003
- Na+-K+-ATPase α2-gene and skeletal muscle characteristics in response to long-term overfeeding, Ukkola, O., Joanisse, D.R., Tremblay, A., Bouchard, C., Journal of Applied Physiology, 2003
- Skeletal muscle enzymes as predictors of 24-h energy metabolism in reduced-obese persons, Doucet, E., Tremblay, A., Simoneau, J.-A., Joanisse, D.R., American Journal of Clinical Nutrition, 2003
- Age is independently related to muscle metabolic capacity in premenopausal women., Hunter GR, Newcomer BR, Weinsier RL, Karapondo DL, Larson-Meyer DE, Joanisse DR, Bamman MM, 2002, 10.1152/japplphysiol.01239.2001
- Skeletal muscle characteristics predict body fat gain in response to overfeeding in never-obese young men., Sun G, Ukkola O, Rankinen T, Joanisse DR, Bouchard C, 2002, 10.1053/meta.2002.31324
- Weight loss-induced rise in plasma pollutant is associated with reduced skeletal muscle oxidative capacity., Imbeault P, Tremblay A, Simoneau JA, Joanisse DR, 2002, 10.1152/ajpendo.00394.2001
- Age is independently related to muscle metabolic capacity in premenopausal women, Hunter, G.R., Newcomer, B.R., Weinsier, R.L., Karapondo, D.L., Enette Larson-Meyer, D., Joanisse, D.R., Bamman, M.M., Journal of Applied Physiology, 2002
- Weight loss-induced rise in plasma pollutant is associated with reduced skeletal muscle oxidative capacity, Imbeault, P., Tremblay, A., Simoneau, J.-A., Joanisse, D.R., American Journal of Physiology - Endocrinology and Metabolism, 2002
- Relation between in vivo and in vitro measurements of skeletal muscle oxidative metabolism., Larson-Meyer DE, Newcomer BR, Hunter GR, Joanisse DR, Weinsier RL, Bamman MM, 2001, 10.1002/mus.1202
- Fat content in individual muscle fibers of lean and obese subjects., Malenfant P, Joanisse DR, Thériault R, Goodpaster BH, Kelley DE, Simoneau JA, 2001, 10.1038/sj.ijo.0801733
- Elevated intramyocellular lipid concentration in obese subjects is not reduced after diet and exercise training., Malenfant P, Tremblay A, Doucet E, Imbeault P, Simoneau JA, Joanisse DR, 2001
- Elevated intramyocellular lipid concentration in obese subjects is not reduced after diet and exercise training, Malenfant, P., Tremblay, A., Doucet, E., Imbeault, P., Simoneau, J.-A., Joanisse, D.R., American Journal of Physiology - Endocrinology and Metabolism, 2001
- The stimulation-induced increase in skeletal muscle glycogen synthase content is impaired in carriers of the glycogen synthase XbaI gene polymorphism, St-Onge, J., Joanisse, D.R., Simoneau, J.-A., Diabetes, 2001
- The stimulation-induced increase in skeletal muscle glycogen synthase content is impaired in carriers of the glycogen synthase XbaI gene polymorphism., St-Onge J, Joanisse DR, Simoneau JA, 2001, 10.2337/diabetes.50.1.195
- Cloning and developmental expression of a nuclear ubiquitin-conjugating enzyme (DmUbc9) that interacts with small heat shock proteins in Drosophila melanogaster., Joanisse DR, Inaguma Y, Tanguay RM, 1998, 10.1006/bbrc.1998.8214
- Oxidative stress and antioxidants in stress and recovery of cold-hardy insects, Denis R Joanisse, Kenneth B Storey, Insect Biochemistry and Molecular Biology, 1998, 10.1016/s0965-1748(97)00070-2
- Small heat shock proteins of Drosophila: Developmental expression and functions, Joanisse, D.R., Michaud, S., Inaguma, Y., Tanguay, R.M., Journal of Biosciences, 1998
- Fatty Acid Content and Enzymes of Fatty Acid Metabolism in Overwintering Cold-Hardy Gall Insects, Denis R. Joanisse, Kenneth B. Storey, Physiological Zoology, 1996, 10.1086/physzool.69.5.30164247
- Oxidative damage and antioxidants in Rana sylvatica, the freeze-tolerant wood frog., Joanisse DR, Storey KB, 1996
- Fatty acid content and enzymes of fatty acid metabolism in overwintering cold-hardy gall insects, Joanisse, D.R., Storey, K.B., Physiological Zoology, 1996
- Oxidative damage and antioxidants in Rana sylvatica, the freeze-tolerant wood frog, Joanisse, D.R., Storey, K.B., American Journal of Physiology - Regulatory Integrative and Comparative Physiology, 1996
- Oxidative stress and antioxidants in overwintering larvae of cold-hardy goldenrod gall insects, Joanisse D, Storey K, 1996
- Oxidative stress and antioxidants in overwintering larvae of cold-hardy goldenrod gall insects, Joanisse, D.R., Storey, K.B., Journal of Experimental Biology, 1996
- Temperature acclimation and seasonal responses by enzymes in cold-hardy gall insects, Denis R. Joanisse, Kenneth B. Storey, Arch. Insect Biochem. Physiol., 1995, 10.1002/arch.940280404
- Enzyme activity profiles in an overwintering population of freeze-avoiding gall moth larvae, Epiblema scudderiana, Denis R. Joanisse, Kenneth B. Storey, Can. J. Zool., 1994, 10.1139/z94-145
- Enzyme activity profiles in an overwintering population of freeze-avoiding gall moth larvae, Epiblema scudderiana., Joanisse DR, Storey KB, 1994
- Mitochondrial enzymes during overwintering in two species of cold-hardy gall insects, Denis R. Joanisse, Kenneth B. Storey, Insect Biochemistry and Molecular Biology, 1994, 10.1016/0965-1748(94)90080-9
- Enzyme activity profiles in an overwintering population of freeze-avoiding gall moth larvae, Epiblema scudderiana, Joanisse, D.R., Storey, K.B., Canadian Journal of Zoology, 1994
- Enzyme activity profiles in an overwintering population of freeze-tolerant larvae of the gall fly, Eurosta solidaginis, Joanisse, D.R., Storey, K.B., Journal of Comparative Physiology B, 1994, 10.1007/BF00354086
- Freeze tolerance in hermit flower beetle (Osmoderma eremicola) larvae, Kenneth B. Storey, Thomas A. Churchill, Denis R. Joanisse, Journal of Insect Physiology, 1993, 10.1016/0022-1910(93)90048-v
...
Contribution à l'enseignement aux cycles supérieurs
Étudiant(e)s dirigé(e)s*
Depuis 2009- Tamara Bisson - Maitrîse avec mémoire - En cours
- Sabrina Bergeron - Maitrîse avec mémoire - En cours
- Paul Peyrel - Doctorat - En cours
- Eve-Julie Tremblay - Maitrîse avec mémoire - En cours
- Pénélope Paradis-Deschênes - Maitrîse avec mémoire - 2015/09
- Andrée-Anne Clément - Maitrîse avec mémoire - 2019/09
- Emma Galbraith - Maitrîse avec mémoire - 2020/05
- Nicolas Chabot - Maitrîse avec mémoire - 2021/09
Encadrement d'étudiant(e)s pour les programmes suivants :
*Les supervisions d’étudiant(e)s de 1er cycle en
stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées
ultérieurement.