Arnaud Droit

Professeur titulaire

arnaud.droit@fmed.ulaval.ca

Site personnel

Département de médecine moléculaire

Centre de recherche sur le cancer

Centre de recherche en données massives

Centre de recherche du CHU de Québec - Université Laval

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Contribution à la recherche

Axe de recherche de l'Université Laval :

Santé et bien-être durables

Thématiques de recherche de la Faculté de médecine :

Bioinformatique / données massives (big data)

Domaines et intérêts de recherche du (de la) professeur(e) :

Cancer

Cancer du sein
Cancer la prostate
Environnement et cancer
Lymphomes
Nutrition et cancer
Diagnostic et détection du cancer

Neurosciences, santé mentale et toxicomanies

Génétique des maladies neurologiques et psychiatriques
Maladies neurodégénératives
Migraine
Autisme

Projets de recherche

L’AIMZ-938, un nouveau promédicament anticancéreux pour le traitement des cancers du sein humain réfractaires aux traitements actuels et exprimant le cytochrome P450 1A1 - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2021-10-01 au 2026-09-30
Chaire de recherche et d'innovation l'Oréal en biologie numérique - L'Oréal - Chaires de recherche sans organismes subventionnaires, chercheur principal - 2016-05-16 au 2026-05-15
Therapeutic approach to preserve Tfh cells and improve B cell immunity in simian immunodeficiency virus infected rhesus macaques - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2021-04-01 au 2026-03-31
Outil d'intelligence artificielle pour l'identification rapide et précise des micro-organismes dans le lait - Ministère de l'agriculture, des pêcheries et de l'alimentation - Innov'Action volet 1, chercheur principal - 2022-03-24 au 2025-04-30
Delineation of the epigenomic principles underlying microglial transcriptional and cellular activity in chronic neurodegenerative diseases - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2020-03-01 au 2025-03-31
Nouvelle approche intégrative de génomique du microbiome pour des luzernières plus durables - Génome Québec - Programme d’intégration de la génomique, chercheur principal - 2022-05-01 au 2024-04-30
Outil d'intelligence artificielle pour l'identification rapide et précise des bactéries pathogènes chez les animaux et/ou chez l'humain dans le lait et les produits laitiers - Fonds de recherche du Québec - Nature et technologies - Projet de recherche en équipe, chercheur principal - 2021-04-01 au 2024-03-31
Observatoire international sur les impacts sociétaux de l'intelligence artificielle et du numérique - Fonds de recherche du Québec - Société et culture, Université Laval - Fonds internes - Appel à propositions : création d’un Observatoire international sur les impacts sociétaux de l’intelligence artificielle et du numérique, co-chercheur - 2018-04-01 au 2024-03-31
Caractérisation de la structure 3D et de la coloration des perles chez Pinctada sp. par analyse d’image. - Institut français de recherche pour l'exploitation de la mer, chercheur principal - 2021-01-01 au 2023-12-31
Caribou Genomics : a National Non-Invasive Monitoring Approach for an Iconic and Model Species-at-Risk - Environnement Canada et Changement Climatique, Génome Canada - Programme de partenariats pour les applications de la génomique (PPAG), Trent University, co-chercheur - 2020-10-01 au 2023-09-30
Utilisation du séquençage à haut débit pour l’identification d’organismes pathogènes des plantes - Ministère de l'agriculture, des pêcheries et de l'alimentation - Prime-Vert : Programme de soutien financier, Institut de recherche et de développement en agroenvironnement, co-chercheur - 2019-08-01 au 2023-08-31
Nouvelle approche moléculaire pour la détection simultanée des virus pathogènes aux framboisiers et aux fraisiers - Ministère de l'agriculture, des pêcheries et de l'alimentation - Prime-Vert : Programme de soutien financier, Institut de recherche et de développement en agroenvironnement, co-chercheur - 2019-08-01 au 2023-08-31
Development of high accuracy models for MICROB-AI, a new generation of diagnosis test for UTI - Génome Québec - Programme d’intégration de la génomique, chercheur principal - 2021-04-01 au 2023-06-30
Cellular mechanisms regulating the pathogenesis of secondary progressive CNS autoimmunity - Instituts de recherche en santé du Canada - Subvention Projet, co-chercheur - 2018-10-01 au 2023-03-31
Identifying novel molecular insights from life science massive data - Conseil de recherches en sciences naturelles et génie Canada, Secrétariat Inter-Conseils (Canada) (CRSH, CRSNG, IRSC) - Subventions à la découverte SD (individuelles et d'équipe), chercheur principal - 2018-04-01 au 2023-03-31
Leveraging the impact of diversity in neurodevelopmental disability by integrating machine learning in personalized interventions - Instituts de recherche en santé du Canada - Canada-UK Artificial Intelligence Initiative, University of Alberta, co-chercheur - 2020-02-01 au 2023-01-31
Predict to prevent: Advanced proteomics profiling for precision medicine - Fondation Canadienne pour l'innovation (La), Ministère de la Santé et des Services sociaux - Fonds des leaders John-R.-Evans (FLJR), chercheur principal - 2021-03-23 au 2022-09-30
Influence of hyperglycemia on the host-microbiome interactions during subgingival microbiome dysbiosis - Biocodex Microbiota Foundation - National Call for projects – Canada, co-chercheur - 2020-12-11 au 2022-06-10
Covid-19 effects on ARTErial StIffness and vascular AgiNg (CARTESIAN) study- Canada - Instituts de recherche en santé du Canada - Subvention de fonctionnement : Possibilité de financement sur les nouveaux besoins prioritaires en recherche sur la COVID-19, co-chercheur - 2021-06-01 au 2022-05-31
Prevention of the immunopathology induced by SARS-CoV-2 - Instituts de recherche en santé du Canada - Subvention de fonctionnement : Possibilité de financement sur les nouveaux besoins prioritaires en recherche sur la COVID-19, co-chercheur - 2021-06-01 au 2022-05-31
Computer-Aided Sperm Analysis (CASA) of sperm motility and hyperactivation - Conseil de recherches en sciences naturelles et génie Canada - Subventions d'outils et d'instruments de recherche (OIR), co-chercheur - 2021-04-01 au 2022-03-31
Dévelooppement d'algorithmes d'interprétation de modèles d'apprentissage profond pour la découverte de biomarqueurs - Fonds France Canada pour la recherche - Nouvelles collaborations de recherche, chercheur principal - 2020-04-01 au 2022-03-31
Use of genomics to manage and protect caribou populations - Managium, Génome Québec - Programme de partenariats pour les applications de la génomique (PPAG), co-chercheur - 2018-04-01 au 2022-03-31
Personalized Risk Assesment for Prevention and Early Detection of Breast Cancer : Integration and Implementation (PERSPECTIVE II) - Regroupement de compagnies et corporations canadiennes, Fondation du CHU de Québec, Génome Québec, Ministère de la santé (Ontario), Ministère de l'Économie, de la Science et de l'Innovation, Instituts de recherche en santé du Canada, Fondation du cancer du sein du Québec, Génome Canada - Projets de recherche appliquée à grande échelle - Large-Scale Applied Research Project, co-chercheur - 2017-11-01 au 2022-03-31
Development of Comprehensive Cytogenomics and Molecular Genetics Testing Using ans Exome and Low-Pass Whole Genome Sequencing Combined Approach - Génome Québec, Génome Canada - Projets de recherche appliquée à grande échelle - Large-Scale Applied Research Project, co-chercheur - 2019-01-01 au 2021-12-31
Impact of the sperm epigenome on the progeny outcome born by assisted reproductive technology - Sick Kids Foundation (The) - New Investigator Research Grants, co-chercheur - 2016-07-01 au 2021-12-31
Une infrastructure IA multi-usagers clé en main pour gérer le cycle de vie complet des données en santé - Université Laval - Fonds internes - BDR - Cas spéciaux et obligations institutionnelles, co-chercheur - 2021-04-01 au 2021-11-30
Développement d'approches par apprentissage actif et en budget contraint à partir de données de cardiologie - MITACS Inc. - Bourse de recherche Mitacs Globalink, chercheur principal - 2021-08-01 au 2021-10-29
Live viral spectroscopy for rapid Covid-19 detection applied directly to clinical biofluids without sample processing - Conseil de recherches en sciences naturelles et génie Canada - Subventions Alliance du CRSNG relatives à la COVID-19, co-chercheur - 2020-08-01 au 2021-07-31
Mise en place d’une application web d’aide à la visualisation et à l’interprétation des analyses de la qualité des sols en culture de pommes de terre - Ministère de l'agriculture, des pêcheries et de l'alimentation, Consortium de recherche sur la pomme de terre du Québec - Programme Innov’Action agroalimentaire, Institut de recherche et de développement en agroenvironnement, co-chercheur - 2019-05-17 au 2021-05-16
Développement d'un nouvel instrument d'analyse en temps réel pour la chirurgie guidée des cancers - Fonds de recherche du Québec - Nature et technologies - Programme Samuel-De Champlain, chercheur principal - 2019-04-01 au 2021-03-31
Calcul Québec - Fonds de recherche du Québec - Nature et technologies, Université Laval - Fonds internes - Regroupements stratégiques NT, Université de Montréal, co-chercheur - 2015-04-01 au 2021-03-31
Father's lasting influence: Molecular foundations of intergenerational transmission of the paternal environment - Instituts de recherche en santé du Canada - Subvention d'équipe : La santé des garçons et des hommes, co-chercheur - 2014-11-01 au 2021-03-31
Toward nutritional and epigenomic interventions in prostate cancer prevention and management - Instituts de recherche en santé du Canada - Fonctionnement: Subvention de promotion de l’impact - CCREES, co-chercheur - 2017-10-01 au 2020-09-30

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Publications

New Developments and Possibilities in Reanalysis and Reinterpretation of Whole Exome Sequencing Datasets for Unsolved Rare Diseases Using Machine Learning Approaches, Samarth Thonta Setty, Marie-Pier Scott-Boyer, Tania Cuppens, Arnaud Droit, International Journal of Molecular Sciences, 2022, 10.3390/ijms23126792
Cis-regulatory hubs: a new 3D model of complex disease genetics with an application to schizophrenia, Loïc Mangnier, Charles Joly-Beauparlant, Arnaud Droit, Steve Bilodeau, Alexandre Bureau, Life Science Alliance, 2022, 10.26508/lsa.202101156
DIA proteomics data from a UPS1-spiked E.coli protein mixture processed with six software tools, Clarisse Gotti, Florence Roux-Dalvai, Charles Joly-Beauparlant, Loïc Mangnier, Mickaël Leclercq, Arnaud Droit, Data in Brief, 2022, 10.1016/j.dib.2022.107829
Interpretation of network-based integration from multi-omics longitudinal data, Antoine Bodein, Marie-Pier Scott-Boyer, Olivier Perin, Kim-Anh Lê Cao, Arnaud Droit, Nucleic Acids Research, 2022, 10.1093/nar/gkab1200
CNVs with adaptive potential in Rangifer tarandus: genome architecture and new annotated assembly, Julien Prunier, Alexandra Carrier, Isabelle Gilbert, William Poisson, Vicky Albert, Joëlle Taillon, Vincent Bourret, Steeve D Côté, Arnaud Droit, Claude Robert, Life Science Alliance, 2022, 10.26508/lsa.202101207
timeOmics: an R package for longitudinal multi-omics data integration, Antoine Bodein, Marie-Pier Scott-Boyer, Olivier Perin, Kim-Anh Lê Cao, Arnaud Droit, Bioinformatics, 2022, 10.1093/bioinformatics/btab664
Vitamin C Differentially Impacts the Serum Proteome Profile in Female and Male Mice, Lucie Aumailley, Sylvie Bourassa, Clarisse Gotti, Arnaud Droit, Michel Lebel, Journal of Proteome Research, 2021, 10.1021/acs.jproteome.1c00542
Proteomic Analysis of Maternal Urine for the Early Detection of Preeclampsia and Fetal Growth Restriction, Emmanuel Bujold, Alexandre Fillion, Florence Roux-Dalvai, Marie Pier Scott-Boyer, Yves Giguère, Jean-Claude Forest, Clarisse Gotti, Geneviève Laforest, Paul Guerby, Arnaud Droit, Journal of Clinical Medicine, 2021, 10.3390/jcm10204679
Extensive and Accurate Benchmarking of DIA Acquisition Methods and Software Tools Using a Complex Proteomic Standard, Clarisse Gotti, Florence Roux-Dalvai, Charles Joly-Beauparlant, Loïc Mangnier, Mickaël Leclercq, Arnaud Droit, Journal of Proteome Research, 2021, 10.1021/acs.jproteome.1c00490
KibioR & Kibio: a new architecture for next-generation data querying and sharing in big biology, Régis Ongaro-Carcy, Marie-Pier Scott-Boyer, Adrien Dessemond, François Belleau, Mickael Leclercq, Olivier Périn, Arnaud Droit, Bioinformatics, 2021, 10.1093/bioinformatics/btab157
Personalized Risk Assessment for Prevention and Early Detection of Breast Cancer: Integration and Implementation (PERSPECTIVE I&I), Jennifer Brooks, Hermann Nabi, Irene Andrulis, Antonis Antoniou, Jocelyne Chiquette, Philippe Després, Peter Devilee, Michel Dorval, Arnaud Droit, Douglas Easton, Andrea Eisen, Laurence Eloy, Samantha Fienberg, David Goldgar, Eric Hahnen, Yann Joly, Bartha Knoppers, Aisha Lofters, Jean-Yves Masson, Nicole Mittmann, Jean-Sébastien Paquette, Nora Pashayan, Rita Schmutzler, Tracy Stockley, Sean Tavtigian, Meghan Walker, Michael Wolfson, Anna Chiarelli, Jacques Simard, Journal of Personalized Medicine, 2021, 10.3390/jpm11060511
Early-Life Exposure to Environmental Contaminants Perturbs the Sperm Epigenome and Induces Negative Pregnancy Outcomes for Three Generations via the Paternal Lineage, Maurice Clotilde, Mathieu Dalvai, Romain Lambrot, Astrid Deschênes, Marie-Pier Scott-Boyer, Serge McGraw, Donovan Chan, Nancy Côté, Ayelet Ziv-Gal, Jodi Flaws, Arnaud Droit, Jacquetta Trasler, Sarah Kimmins, Janice Bailey, Epigenomes, 2021, 10.3390/epigenomes5020010
Modulating HSF1 levels impacts expression of the estrogen receptor α and antiestrogen response, Maruhen AD Silveira, Christophe Tav, Félix-Antoine Bérube-Simard, Tania Cuppens, Mickaël Leclercq, Éric Fournier, Maxime C Côté, Arnaud Droit, Steve Bilodeau, Life Science Alliance, 2021, 10.26508/lsa.202000811
ETumorMetastasis: A Network-based Algorithm Predicts Clinical Outcomes Using Whole-exome Sequencing Data of Cancer Patients, Jean-Sébastien Milanese, Chabane Tibiche, Naif Zaman, Jinfeng Zou, Pengyong Han, Zhigang Meng, Andre Nantel, Arnaud Droit, Edwin Wang, Genomics, Proteomics & Bioinformatics, 2021, 10.1016/j.gpb.2020.06.009
Dairy product intake modifies gut microbiota composition among hyperinsulinemic individuals, Khorraminezhad, L., Leclercq, M., O’Connor, S., Julien, P., Weisnagel, S.J., Gagnon, C., Droit, A., Rudkowska, I., European Journal of Nutrition, 2021, 10.1007/s00394-020-02226-z
Interactions with plant pathogens influence lipopeptides production and antimicrobial activity of Bacillus subtilis strain PTB185, Cossus, L., Roux-Dalvai, F., Kelly, I., Nguyen, T.T.A., Antoun, H., Droit, A., Tweddell, R.J., Biological Control, 2021, 10.1016/j.biocontrol.2020.104497
Extensive and accurate benchmarking of DIA acquisition methods and software tools using a complex proteomic standard, , 2020, 10.1101/2020.11.03.365585
Interpretation of network-based integration from multi-omics longitudinal data, , 2020, 10.1101/2020.11.02.365593
LY75 Ablation Mediates Mesenchymal-Epithelial Transition (MET) in Epithelial Ovarian Cancer (EOC) Cells Associated with DNA Methylation Alterations and Suppression of the Wnt/β-Catenin Pathway, Sadia Mehdi, Magdalena Bachvarova, Marie-Pier Scott-Boyer, Arnaud Droit, Dimcho Bachvarov, International Journal of Molecular Sciences, 2020, 10.3390/ijms21051848
Adipose Tissue Transcriptome Is Related to Pollutant Exposure in Polar Bear Mother-Cub Pairs from Svalbard, Norway, Herst, P.M., Aars, J., Joly Beauparlant, C., Bodein, A., Dalvai, M., Gagné, D., Droit, A., Bailey, J.L., Routti, H., Environmental Science and Technology, 2020, 10.1021/acs.est.0c01920
Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influence on progression, Lévesque, E., Labriet, A., Hovington, H., Allain, É.P., Melo-Garcia, L., Rouleau, M., Brisson, H., Turcotte, V., Caron, P., Villeneuve, L., Leclercq, M., Droit, A., Audet-Walsh, E., Simonyan, D., Fradet, Y., Lacombe, L., Guillemette, C., British Journal of Cancer, 2020, 10.1038/s41416-020-0749-2
Complexity of the microRNA transcriptome of cow milk and milk-derived extracellular vesicles isolated via differential ultracentrifugation, Benmoussa, A., Laugier, J., Beauparlant, C.J., Lambert, M., Droit, A., Provost, P., Journal of Dairy Science, 2020, 10.3168/jds.2019-16880
Cumulative learning enables convolutional neural network representations for small mass spectrometry data classification, , Nature Communication, 2020, 10.1038/s41467-020-19354-z
DSNetwork: An Integrative Approach to Visualize Predictions of Variants’ Deleteriousness, Lemaçon, A., Scott-Boyer, M.-P., Ongaro-Carcy, R., Soucy, P., Simard, J., Droit, A., Frontiers in Genetics, 2020, 10.3389/fgene.2019.01349
FcgRIIA expression accelerates nephritis and increases platelet activation in systemic lupus erythematosus, Melki, I., Allaeys, I., Tessandier, N., Mailhot, B., Cloutier, N., Campbell, R.A., Rowley, J.W., Salem, D., Zufferey, A., Laroche, A., Lévesque, T., Patey, N., Rauch, J., Lood, C., Droit, A., McKenzie, S.E., Machlus, K.R., Rondina, M.T., Lacroix, S., Fortin, P.R., Boilard, E., Blood, 2020, 10.1182/blood.2020004974
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes, Fachal, L., Aschard, H., Beesley, J., Barnes, D.R., Allen, J., Kar, S., Pooley, K.A., Dennis, J., Michailidou, K., Turman, C., Soucy, P., Lemaçon, A., Lush, M., Tyrer, J.P., Ghoussaini, M., Marjaneh, M.M., Jiang, X., Agata, S., Aittomäki, K., Alonso, M.R., Andrulis, I.L., Anton-Culver, H., Antonenkova, N.N., Arason, A., Arndt, V., Aronson, K.J., Arun, B.K., Auber, B., Auer, P.L., Azzollini, J., Balmaña, J., Barkardottir, R.B., Barrowdale, D., Beeghly-Fadiel, A., Benitez, J., Bermisheva, M., Bialkowska, K., Blanco, A.M., Blomqvist, C., Blot, W., Bogdanova, N.V., Bojesen, S.E., Bolla, M.K., Bonanni, B., Borg, A., Bosse, K., Brauch, H., Brenner, H., Briceno, I., Brock, I.W., Brooks-Wilson, A., Brüning, T., Burwinkel, B., Buys, S.S., Cai, Q., Caldés, T., Caligo, M.A., Camp, N.J., Campbell, I., Canzian, F., Carroll, J.S., Carter, B.D., Castelao, J.E., Chiquette, J., Christiansen, H., Chung, W.K., Claes, K.B.M., Clarke, C.L., Mari, V., Berthet, P., Castera, L., Vaur, D., Lallaoui, H., Bignon, Y.-J., Uhrhammer, N., Bonadona, V., Lasset, C., Révillion, F., Vennin, P., Muller, D., Gomes, D.M., Ingster, O., Coupier, I., Pujol, P., Collonge-Rame, M.-A., Mortemousque, I., Bera, O., Rose, M., Baurand, A., Bertolone, G., Faivre, L., Dreyfus, H., Leroux, D., Venat-Bouvet, L., Bézieau, S., Delnatte, C., Chiesa, J., Gilbert-Dussardier, B., Gesta, P., Prieur, F.P., Bronner, M., Sokolowska, J., Coulet, F., Boutry-Kryza, N., Calender, A., Giraud, S., Leone, M., Fert-Ferrer, S., Stoppa-Lyonnet, D., Jiao, Y., Lesueur, F.L., Mebirouk, N., Barouk-Simonet, E., Bubien, V., Longy, M., Sevenet, N., Gladieff, L., Toulas, C., Reimineras, A., Sobol, H., Paillerets, B.B.-D., Cabaret, O., Caron, O., Guillaud-Bataille, M., Rouleau, E., Belotti, M., Buecher, B., Caputo, S., Colas, C., Pauw, A.D., Fourme, E., Gauthier-Villars, M., Golmard, L., Moncoutier, V., Saule, C., Donaldson, A., Murray, A., Brady, A., Brewer, C., Pottinger, C., Miller, C., Gallagher, D., Gregory, H., Cook, J., Eason, J., Adlard, J., Barwell, J., Ong, K.-R., Snape, K., Walker, L., Izatt, L., Side, L., Tischkowitz, M., Rogers, M.T., Porteous, M.E., Ahmed, M., Morrison, P.J., Brennan, P., Eeles, R., Davidson, R., Collée, J.M., Cornelissen, S., Couch, F.J., Cox, A., Cross, S.S., Cybulski, C., Czene, K., Daly, M.B., de la Hoya, M., Devilee, P., Diez, O., Ding, Y.C., Dite, G.S., Domchek, S.M., Dörk, T., dos-Santos-Silva, I., Droit, A., Dubois, S., Dumont, M., Duran, M., Durcan, L., Dwek, M., Eccles, D.M., Engel, C., Eriksson, M., Evans, D.G., Fasching, P.A., Fletcher, O., Floris, G., Flyger, H., Foretova, L., Foulkes, W.D., Friedman, E., Fritschi, L., Frost, D., Gabrielson, M., Gago-Dominguez, M., Gambino, G., Ganz, P.A., Gapstur, S.M., Garber, J., García-Sáenz, J.A., Gaudet, M.M., Georgoulias, V., Giles, G.G., Glendon, G., Godwin, A.K., Goldberg, M.S., Goldgar, D.E., González-Neira, A., Tibiletti, M.G., Greene, M.H., Grip, M., Gronwald, J., Grundy, A., Guénel, P., Hahnen, E., Haiman, C.A., Håkansson, N., Hall, P., Hamann, U., Harrington, P.A., Hartikainen, J.M., Hartman, M., He, W., Healey, C.S., Heemskerk-Gerritsen, B.A.M., Heyworth, J., Hillemanns, P., Hogervorst, F.B.L., Hollestelle, A., Hooning, M.J., Hopper, J.L., Howell, A., Huang, G., Hulick, P.J., Imyanitov, E.N., Sexton, A., Christian, A., Trainer, A., Spigelman, A., Fellows, A., Shelling, A., Fazio, A.D., Blackburn, A., Crook, A., Meiser, B., Patterson, B., Clarke, C., Saunders, C., Hunt, C., Scott, C., Amor, D., Marsh, D., Edkins, E., Salisbury, E., Haan, E., Neidermayr, E., Macrea, F., Farshid, G., Lindeman, G., Trench, G., Mann, G., Gill, G., Thorne, H., Hickie, I., Winship, I., Flanagan, J., Kollias, J., Visvader, J., Stone, J., Burke, J., Saunus, J., Forbes, J., Kirk, J., French, J., Tucker, K., Wu, K., Phillips, K., Lipton, L., Andrews, L., Lobb, L., Kentwell, M., Spurdle, M., Cummings, M., Gleeson, M., Harris, M., Jenkins, M., Young, M.A., Delatycki, M., Wallis, M., Burgess, M., Price, M., Brown, M., Southey, M.C., Bogwitz, M., Field, M., Friedlander, M., Gattas, M., Saleh, M., Hayward, N., Pachter, N., Cohen, P., Duijf, P., James, P., Simpson, P., Fong, P., Butow, P., Williams, R., Kefford, R., Scott, R., Milne, R., Balleine, R., Dawson, S.–J., Lok, S., O’Connell, S., Greening, S., Nightingale, S., Edwards, S.L., Fox, S., McLachlan, S.-A., Lakhani, S., Antill, Y., Aalfs, C., Meijers-Heijboer, H., van Engelen, K., Gille, H., Boere, I., Collée, M., van Deurzen, C., Obdeijn, I.-M., van den Ouweland, A., Seynaeve, C.M., Siesling, S., Verloop, J., van Asperen, C.J., van Cronenburg, T., Blok, R., de Boer, M., Garcia, E.G., Adank, M., Hogervorst, F., Jenner, D., van Leeuwen, F., Rookus, M., Russell, N., Schmidt, M., van den Belt-Dusebout, S., Kets, C., Mensenkamp, A., de Bock, T., van der Hout, A., Mourits, M., Oosterwijk, J., Ausems, M., Koudijs, M., Baxter, R., Yip, D., Carpenter, J., Davis, A., Pathmanathan, N., Graham, D., Sachchithananthan, M., Isaacs, C., Iwasaki, M., Jager, A., Jakimovska, M., Jakubowska, A., James, P.A., Janavicius, R., Jankowitz, R.C., John, E.M., Johnson, N., Jones, M.E., Jukkola-Vuorinen, A., Jung, A., Kaaks, R., Kang, D., Kapoor, P.M., Karlan, B.Y., Keeman, R., Kerin, M.J., Khusnutdinova, E., Kiiski, J.I., Kirk, J., Kitahara, C.M., Ko, Y.-D., Konstantopoulou, I., Kosma, V.-M., Koutros, S., Kubelka-Sabit, K., Kwong, A., Kyriacou, K., Laitman, Y., Lambrechts, D., Lee, E., Leslie, G., Lester, J., Lesueur, F., Lindblom, A., Lo, W.-Y., Long, J., Lophatananon, A., Loud, J.T., Lubinski, J., MacInnis, R.J., Maishman, T., Makalic, E., Mannermaa, A., Manoochehri, M., Manoukian, S., Margolin, S., Martinez, M.E., Matsuo, K., Maurer, T., Mavroudis, D., Mayes, R., McGuffog, L., McLean, C., Meindl, A., Miller, A., Miller, N., Montagna, M., Moreno, F., Muir, K., Mulligan, A.M., Muñoz-Garzon, V.M., Muranen, T.A., Narod, S.A., Nassir, R., Nathanson, K.L., Neuhausen, S.L., Nevanlinna, H., Neven, 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Glutamine supplementation improves the efficacy of miltefosine treatment for visceral leishmaniasis, Ferreira, C., Mesquita, I., Barbosa, A.M., Osório, N.S., Torrado, E., Beauparlant, C.-J., Droit, A., Cunha, C., Carvalho, A., Saha, B., Estaquier, J., Silvestre, R., PLoS Neglected Tropical Diseases, 2020, 10.1371/journal.pntd.0008125
Hedgehog signaling pathway regulates gene expression profile of epididymal principal cells through the primary cilium, Girardet, L., Bernet, A., Calvo, E., Soulet, D., Joly-Beauparlant, C., Droit, A., Cyr, D.G., Belleannée, C., FASEB Journal, 2020, 10.1096/fj.202000328R
Identification of a Transcriptomic Prognostic Signature by Machine Learning Using a Combination of Small Cohorts of Prostate Cancer, Vittrant, B., Leclercq, M., Martin-Magniette, M.-L., Collins, C., Bergeron, A., Fradet, Y., Droit, A., Frontiers in Genetics, 2020, 10.3389/fgene.2020.550894
Identification of the most important features of knee osteoarthritis structural progressors using machine learning methods, Jamshidi, A., Leclercq, M., Labbe, A., Pelletier, J.-P., Abram, F., Droit, A., Martel-Pelletier, J., Therapeutic Advances in Musculoskeletal Disease, 2020, 10.1177/1759720X20933468
Immune-focused multi-omics analysis of prostate cancer: leukocyte Ig-Like receptors are associated with disease progression, Vittrant, B., Bergeron, A., Molina, O.E., Leclercq, M., Légaré, X.-P., Hovington, H., Picard, V., Martin-Magniette, M.-L., Livingstone, J., Boutros, P.C., Collins, C., Fradet, Y., Droit, A., OncoImmunology, 2020, 10.1080/2162402X.2020.1851950
Neuronal interleukin-1 receptors mediate pain in chronic inflammatory diseases, Mailhot, B., Christin, M., Tessandier, N., Sotoudeh, C., Bretheau, F., Turmel, R., Pellerin, E., Wang, F., Bories, C., Joly-Beauparlant, C., De Koninck, Y., Droit, A., Cicchetti, F., Scherrer, G., Boilard, E., Sharif-Naeini, R., Lacroix, S., Journal of Experimental Medicine, 2020, 10.1084/jem.20191430
Statistical and machine-learning analyses in nutritional genomics studies, Khorraminezhad, L., Leclercq, M., Droit, A., Bilodeau, J.-F., Rudkowska, I., Nutrients, 2020, 10.3390/nu12103140
The Absence of HIF-1α Increases Susceptibility to Leishmania donovani Infection via Activation of BNIP3/mTOR/SREBP-1c Axis, Mesquita, I., Ferreira, C., Moreira, D., Kluck, G.E.G., Barbosa, A.M., Torrado, E., Dinis-Oliveira, R.J., Gonçalves, L.G., Beauparlant, C.-J., Droit, A., Berod, L., Sparwasser, T., Bodhale, N., Saha, B., Rodrigues, F., Cunha, C., Carvalho, A., Castro, A.G., Estaquier, J., Silvestre, R., Cell Reports, 2020, 10.1016/j.celrep.2020.02.098
UGT2B17 modifies drug response in chronic lymphocytic leukaemia, Allain, E.P., Rouleau, M., Vanura, K., Tremblay, S., Vaillancourt, J., Bat, V., Caron, P., Villeneuve, L., Labriet, A., Turcotte, V., Le, T., Shehata, M., Schnabl, S., Demirtas, D., Hubmann, R., Joly-Beauparlant, C., Droit, A., Jäger, U., Staber, P.B., Lévesque, E., Guillemette, C., British Journal of Cancer, 2020, 10.1038/s41416-020-0887-6
A Generic Multivariate Framework for the Integration of Microbiome Longitudinal Studies With Other Data Types, Bodein, A., Chapleur, O., Droit, A., Lê Cao, K.-A., Frontiers in Genetics, 2019, 10.3389/fgene.2019.00963
Deletion of the MIZ-1 POZ domain increases efficacy of cytarabine treatment in T- And B-ALL/lymphoma mouse models, Ross, J., Rashkovan, M., Fraszczak, J., Joly-Beauparlant, C., Vadnais, C., Winkler, R., Droit, A., Kosan, C., Moroy, T., Cancer Research, 2019, 10.1158/0008-5472.CAN-18-3038
Fast and accurate bacterial species identification in urine specimens using LC-MS/MS mass spectrometry and machine learning, Roux-Dalvai, F., Gotti, C., Leclercq, M., Hélie, M.-C., Boissinot, M., Arrey, T.N., Dauly, C., Fournier, F., Kelly, I., Marcoux, J., Bestman-Smith, J., Bergeron, M.G., Droit, A., Molecular and Cellular Proteomics, 2019, 10.1074/mcp.TIR119.001559
Folic acid supplementation reduces multigenerational sperm miRNA perturbation induced by in utero environmental contaminant exposure, , Environmental Epigenetics, 2019, 10.1093/eep/dvz024
Increased Dairy Product Intake Alters Serum Metabolite Profiles in Subjects at Risk of Developing Type 2 Diabetes, O'Connor, S., Greffard, K., Leclercq, M., Julien, P., Weisnagel, S.J., Gagnon, C., Droit, A., Bilodeau, J.-F., Rudkowska, I., Molecular Nutrition and Food Research, 2019, 10.1002/mnfr.201900126
Large-scale automatic feature selection for biomarker discovery in high-dimensional omics data, Leclercq, M., Vittrant, B., Martin-Magniette, M.L., Scott Boyer, M.P., Perin, O., Bergeron, A., Fradet, Y., Droit, A., Frontiers in Genetics, 2019, 10.3389/fgene.2019.00452
LD-annot: A Bioinformatics Tool to Automatically Provide Candidate SNPs With Annotations for Genetically Linked Genes, Prunier, J., Lemaçon, A., Bastien, A., Jafarikia, M., Porth, I., Robert, C., Droit, A., Frontiers in Genetics, 2019, 10.3389/fgene.2019.01192
Portrait of blood-derived extracellular vesicles in patients with Parkinson's disease, Lamontagne-Proulx, J., St-Amour, I., Labib, R., Pilon, J., Denis, H.L., Cloutier, N., Roux-Dalvai, F., Vincent, A.T., Mason, S.L., Williams-Gray, C., Duchez, A.-C., Droit, A., Lacroix, S., Dupré, N., Langlois, M., Chouinard, S., Panisset, M., Barker, R.A., Boilard, E., Cicchetti, F., Neurobiology of Disease, 2019, 10.1016/j.nbd.2018.11.002
Prenatal Exposure to Environmentally-Relevant Contaminants Perturbs Male Reproductive Parameters Across Multiple Generations that are Partially Protected by Folic Acid Supplementation, Lessard, M., Herst, P.M., Charest, P.L., Navarro, P., Joly-Beauparlant, C., Droit, A., Kimmins, S., Trasler, J., Benoit-Biancamano, M.-O., MacFarlane, A.J., Dalvai, M., Bailey, J.L., Scientific Reports, 2019, 10.1038/s41598-019-50060-z
RNA sequencing data of human prostate cancer cells treated with androgens, Poluri, R.T.K., Beauparlant, C.J., Droit, A., Audet-Walsh, É., Data in Brief, 2019, 10.1016/j.dib.2019.104372
The Ovulatory Signal Precipitates LRH-1 Transcriptional Switching Mediated by Differential Chromatin Accessibility, Bianco, S., Bellefleur, A.-M., Beaulieu, É., Beauparlant, C.J., Bertolin, K., Droit, A., Schoonjans, K., Murphy, B.D., Gévry, N., Cell Reports, 2019, 10.1016/j.celrep.2019.07.088
Transcriptomic profile of the subiculum-projecting VIP GABAergic neurons in the mouse CA1 hippocampus, Luo, X., Muñoz-Pino, E., Francavilla, R., Vallée, M., Droit, A., Topolnik, L., Brain Structure and Function, 2019, 10.1007/s00429-019-01883-z
A type 2 diabetes disease module with a high collective influence for Cdk2 and PTPLAD1 is localized in endosomes, Boutchueng-Djidjou, M., Belleau, P., Bilodeau, N., Fortier, S., Bourassa, S., Droit, A., Elowe, S., Faure, R.L., PLoS ONE, 2018, 10.1371/journal.pone.0205180
Erratum: Inferring and modeling inheritance of differentially methylated changes across multiple generations (Nucleic acids research (2018) 46 14 (e85)), Belleau, P., Deschênes, A., Scott-Boyer, M.-P., Lambrot, R., Dalvai, M., Kimmins, S., Bailey, J., Droit, A., Nucleic acids research, 2018, 10.1093/nar/gky477
Implementing a web-based introductory bioinformatics course for non-bioinformaticians that incorporates practical exercises, Vincent, A.T., Bourbonnais, Y., Brouard, J.-S., Deveau, H., Droit, A., Gagné, S.M., Guertin, M., Lemieux, C., Rathier, L., Charette, S.J., Lagüe, P., Biochemistry and Molecular Biology Education, 2018, 10.1002/bmb.21086
Inferring and modeling inheritance of differentially methylated changes across multiple generations, Belleau, P., Deschênes, A., Scott-Boyer, M.-P., Lambrot, R., Dalvai, M., Kimmins, S., Bailey, J., Droit, A., Nucleic acids research, 2018, 10.1093/nar/gky362
Quantitative profiling of the UGT transcriptome in human drug-metabolizing tissues, Tourancheau, A., Rouleau, M., Guauque-Olarte, S., Villeneuve, L., Gilbert, I., Droit, A., Guillemette, C., Pharmacogenomics Journal, 2018, 10.1038/tpj.2017.5
Vitamin C alters the amount of specific endoplasmic reticulum associated proteins involved in lipid metabolism in the liver of mice synthesizing a nonfunctional werner syndrome (Wrn) mutant protein, Aumailley, L., Roux-Dalvai, F., Kelly, I., Droit, A., Lebel, M., PLoS ONE, 2018, 10.1371/journal.pone.0193170
Association analysis identifies 65 new breast cancer risk loci, Michailidou, K., Lindström, S., Dennis, J., Beesley, J., Hui, S., Kar, S., Lemaçon, A., Soucy, P., Glubb, D., Rostamianfar, A., Bolla, M.K., Wang, Q., Tyrer, J., Dicks, E., Lee, A., Wang, Z., Allen, J., Keeman, R., Eilber, U., French, J.D., Chen, X.Q., Fachal, L., McCue, K., Reed, A.E.M., Ghoussaini, M., Carroll, J.S., Jiang, X., Finucane, H., Adams, M., Adank, M.A., Ahsan, H., Aittomäki, K., Anton-Culver, H., Antonenkova, N.N., Arndt, V., Aronson, K.J., Arun, B., Auer, P.L., Bacot, F., Barrdahl, M., Baynes, C., Beckmann, M.W., Behrens, S., Benitez, J., Bermisheva, M., Bernstein, L., Blomqvist, C., Bogdanova, N.V., Bojesen, S.E., Bonanni, B., Børresen-Dale, A.-L., Brand, J.S., Brauch, H., Brennan, P., Brenner, H., Brinton, L., Broberg, P., Brock, I.W., Broeks, A., Brooks-Wilson, A., Brucker, S.Y., Brüning, T., Burwinkel, B., Butterbach, K., Cai, Q., Cai, H., Caldés, T., Canzian, F., Carracedo, A., Carter, B.D., Castelao, 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Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3, Hamdi, Y., Soucy, P., Kuchenbaeker, K.B., Pastinen, T., Droit, A., Lemaçon, A., Adlard, J., Aittomäki, K., Andrulis, I.L., Arason, A., Arnold, N., Arun, B.K., Azzollini, J., Bane, A., Barjhoux, L., Barrowdale, D., Benitez, J., Berthet, P., Blok, M.J., Bobolis, K., Bonadona, V., Bonanni, B., Bradbury, A.R., Brewer, C., Buecher, B., Buys, S.S., Caligo, M.A., Chiquette, J., Chung, W.K., Claes, K.B.M., Daly, M.B., Damiola, F., Davidson, R., De la Hoya, M., De Leeneer, K., Diez, O., Ding, Y.C., Dolcetti, R., Domchek, S.M., Dorfling, C.M., Eccles, D., Eeles, R., Einbeigi, Z., Ejlertsen, B., Engel, C., Gareth Evans, D., Feliubadalo, L., Foretova, L., Fostira, F., Foulkes, W.D., Fountzilas, G., Friedman, E., Frost, D., Ganschow, P., Ganz, P.A., Garber, J., Gayther, S.A., Gerdes, A.-M., Glendon, G., Godwin, A.K., Goldgar, D.E., Greene, M.H., Gronwald, J., Hahnen, E., Hamann, U., Hansen, T.V.O., Hart, S., Hays, J.L., Hogervorst, F.B.L., Hulick, P.J., Imyanitov, E.N., Isaacs, C., Izatt, L., Jakubowska, A., James, P., Janavicius, R., Jensen, U.B., John, E.M., Joseph, V., Just, W., Kaczmarek, K., Karlan, B.Y., Kets, C.M., Kirk, J., Kriege, M., Laitman, Y., Laurent, M., Lazaro, C., Leslie, G., Lester, J., Lesueur, F., Liljegren, A., Loman, N., Loud, J.T., Manoukian, S., Mariani, M., Mazoyer, S., McGuffog, L., Meijers-Heijboer, H.E.J., Meindl, A., Miller, A., Montagna, M., Mulligan, A.M., Nathanson, K.L., Neuhausen, S.L., Nevanlinna, H., Nussbaum, R.L., Olah, E., Olopade, O.I., Ong, K.-R., Oosterwijk, J.C., Osorio, A., Papi, L., Park, S.K., Pedersen, I.S., Peissel, B., Segura, P.P., Peterlongo, P., Phelan, C.M., Radice, P., Rantala, J., Rappaport-Fuerhauser, C., Rennert, G., Richardson, A., Robson, M., Rodriguez, G.C., Rookus, M.A., Schmutzler, R.K., Sevenet, N., Shah, P.D., Singer, C.F., Slavin, T.P., Snape, K., Sokolowska, J., Sønderstrup, I.M.H., Southey, M., Spurdle, A.B., Stadler, Z., Stoppa-Lyonnet, D., Sukiennicki, G., Sutter, C., Tan, Y., Tea, M.-K., Teixeira, M.R., Teulé, A., Teo, S.-H., Terry, M.B., Thomassen, M., Tihomirova, L., Tischkowitz, M., Tognazzo, S., Toland, A.E., Tung, N., van den Ouweland, A.M.W., van der Luijt, R.B., van Engelen, K., van Rensburg, E.J., Varon-Mateeva, R., Wappenschmidt, B., Wijnen, J.T., Rebbeck, T., Chenevix-Trench, G., Offit, K., Couch, F.J., Nord, S., Easton, D.F., Antoniou, A.C., Simard, J., Breast Cancer Research and Treatment, 2017, 10.1007/s10549-016-4018-2
Connected gene communities underlie transcriptional changes in cornelia de lange syndrome, Boudaoud, I., Fournier, É., Baguette, A., Vallée, M., Lamaze, F.C., Droit, A., Bilodeau, S., Genetics, 2017, 10.1534/genetics.117.202291
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer, Milne, R.L., Kuchenbaecker, K.B., Michailidou, K., Beesley, J., Kar, S., Lindström, S., Hui, S., Lemaçon, A., Soucy, P., Dennis, J., Jiang, X., Rostamianfar, A., Finucane, H., Bolla, M.K., McGuffog, L., Wang, Q., Aalfs, C.M., Abctctb, I., Adams, M., Adlard, J., Agata, S., Ahmed, S., Ahsan, H., Aittom, K.A., Fares, A.E., Allen, J., Ambrosone, C.B., Amos, C.I., Andrulis, I.L., Anton-Culver, H., Antonenkova, N.N., Arndt, V., Arnold, N., Aronson, K.J., Auber, B., Auer, P.L., Ausems, M.G.M., Azzollini, J., François, B., Balma, J.N., Barile, M., Barjhoux, L., Barkardottir, R.B., Barrdahl, M., Barnes, D., Barrowdale, D., Baynes, C., Beckmann, M.W., Benitez, J., Bermisheva, M., Bernstein, L., Bignon, Y.J., Blazer, K.R., Blok, M.J., Blomqvist, C., Blot, W., Bobolis, K., Boeckx, B., Bogdanova, N.V., Bojesen, A., Bojesen, S.E., Bonanni, B., Anne-Lise, B.D., Bozsik, A., Bradbury, A.R., Brand, J.S., Brauch, H., Brenner, H., Brigitte, B.-D.P., Brewer, C., Brinton, L., Broberg, P., Angela, B.W., Brunet, J., Brüning, T., Burwinkel, B., Buys, S.S., Byun, J., Cai, Q., Cald, T.E., Caligo, M.A., Campbell, I., Canzian, F., Caron, O., Carracedo, A., Carter, B.D., Esteban, C., Castera, L., Virginie, C.M., Chan, S.B., Jenny, C.C., Chanock, S.J., Chen, X., Cheng, T.-Y.D., Chiquette, J., Christiansen, H., Claes, K.B., Clarke, C.L., Conner, T., Conroy, D.M., Cook, J., Cordina-Duverger, E., Cornelissen, S., Coupier, I., Cox, A., Cox, D.G., Cross, S.S., Cuk, K., Cunningham, J.M., Czene, K., Daly, M.B., Damiola, F., Darabi, H., Davidson, R., Leeneer, K.D.L., Devilee, P., Dicks, E., Diez, O., Ding, Y.C., Ditsch, N., Doheny, K.F., Domchek, S.M., Dorfling, C.M., Dörk, T., Dos-Santos-Silva, I., Dubois, S., Dugué, P.-A., Dumont, M., Dunning, A.M., Durcan, L., Dwek, M., Dworniczak, B., Eccles, D., Eeles, R., Ehrencrona, H., Eilber, U., Ejlertsen, B., Ekici, A.B., Eliassen, A.H., Engel, C., Eriksson, M., Fachal, L., Faivre, L., Fasching, P.A., Faust, U., Figueroa, J., Flesch-Janys, D., Fletcher, O., Flyger, H., Foulkes, W.D., Friedman, E., Fritschi, L., Frost, D., Gabrielson, M., Gaddam, P., Gammon, M.D., Ganz, P.A., Gapstur, S.M., Garber, J., Garcia-Barberan, V., Garciá-Saénz, J.A., Gaudet, M.M., Gauthier-Villars, M., Gehrig, A., Georgoulias, V., Gerdes, A.-M., Giles, G.G., Glendon, G., Godwin, A.K., Goldberg, M.S., Goldgar, D.E., González-Neira, A., Goodfellow, P., Greene, M.H., Grenaker, G.A.I., Grip, M., Gronwald, J., Grundy, A., Gschwantler, D.-K., Guénel, P., Guo, Q., Haeberle, L., Hahnen, E., Haiman, C.A., Håkansson, N., Hallberg, E., Hamann, U., Hamel, N., Hankinson, S., Hansen, T.V., Harrington, P., Hart, S.N., Hartikainen, J.M., Healey, C.S., Hein, A., Helbig, S., Henderson, A., Heyworth, J., Hicks, B., Hillemanns, P., Hodgson, S., Hogervorst, F.B., Hollestelle, A., Hooning, M.J., Hoover, B., Hopper, J.L., Hu, C., Huang, G., Hulick, P.J., Humphreys, K., Hunter, D.J., 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M., MacInnis, R.J., Maishman, T., Makalic, E., Kostovska, I.M., Malone, K.E., Siranoush, M., Manson, J.E., Margolin, S., Martens, J.W., Martinez, M.E., Matsuo, K., Mavroudis, D., Mazoyer, S., McLean, C., Meijers-Heijboer, H., Menéndez, P., Meyer, J., Miao, H., Miller, N., Mitchell, G., Montagna, M., Muir, K., Mulligan, A.M., Mulot, C., Nadesan, S., Nathanson, K.L., Neuhausen, S.L., Nevanlinna, H., Nevelsteen, I., Niederacher, D., Nielsen, S.F., Nordestgaard, B.G., Norman, A., Nussbaum, R.L., Olah, E., Olopade, O.I., Olson, J.E., Olswold, C., Ong, K.-R., Oosterwijk, J.C., Orr, N., Osorio, A., Pankratz, V.S., Papi, L., Park-Simon, T.-W., Paulsson-Karlsson, Y., Lloyd, R., Pedersen, I.S., Peissel, B., Peixoto, A., Perez, J.I., Peterlongo, P., Peto, J., Pfeiler, G., Phelan, C.M., Pinchev, M., Plaseska-Karanfilska, D., Poppe, B., Porteous, M.E., Prentice, R., Presneau, N., Prokofieva, D., Pugh, E., Pujana, M.A., Pylkäs, K., Rack, B., Radice, P., Rahman, N., Rantala, J., Rappaport-Fuerhauser, C., Rennert, G., Rennert, H.S., Rhenius, V., Rhiem, K., Richardson, A., Rodriguez, G.C., Romero, A., Romm, J., Rookus, M.A., Rudolph, A., Ruediger, T., Saloustros, E., Sanders, J., Sandler, D.P., Sangrajrang, S., Sawyer, E.J., Schmidt, D.F., Schoemaker, M.J., Schumacher, F., Schürmann, P., Schwentner, L., Scott, C., Scott, R.J., Seal, S., Senter, L., Seynaeve, C., Shah, M., Sharma, P., Shen, C.-Y., Sheng, X., Shimelis, H., Shrubsole, M.J., Shu, X.-O., Side, L.E., Singer, C.F., Sohn, C., Southey, M.C., Spinelli, J.J., Spurdle, A.B., Stegmaier, C., Stoppa-Lyonnet, D., Sukiennicki, G., Surowy, H., Sutter, C., Swerdlow, A., Szabo, C.I., Tamimi, R.M., Tan, Y.Y., Taylor, J.A., Tejada, M.-I., Tengström, M., Teo, S.H., Terry, M.B., Tessier, D.C., Teul, A.E., Thöne, K., Thull, D.L., Tibiletti, M.G., Tihomirova, L., Tischkowitz, M., Toland, A.E., Tollenaar, R.A.M., Tomlinson, I., Tong, L., Torres, D., Tranchant, M., Truong, T., Tucker, K., Tung, N., Tyrer, J., Ulmer, H.-U., Vachon, C., Christi, V.A.J., Den Berg, D.V., Ouweland, A.M.V., Van Rensburg, E.J., Varesco, L., Varon-Mateeva, R., Vega, A., Viel, A., Vijai, J., Vincent, D., Vollenweider, J., Walker, L., Wang, Z., Wang-Gohrke, S., Wappenschmidt, B., Weinberg, C.R., Weitzel, J.N., Wendt, C., Wesseling, J., Whittemore, A.S., Wijnen, J.T., Willett, W., Winqvist, R., Wolk, A., Wu, A.H., Xia, L., Yang, X.R., Yannoukakos, D., Zaffaroni, D., Zheng, W., Zhu, B., Ziogas, A., Ziv, E., Zorn, K.K., Gago-Dominguez, M., Mannermaa, A., Olsson, H., Teixeira, M.R., Stone, J., Offit, K., Ottini, L., Park, S.K., Thomassen, M., Hall, P., Meindl, A., Schmutzler, R.K., Droit, A., Bader, G.D., Pharoah, P.D., Couch, F.J., Easton, D.F., Kraft, P., Chenevix-Trench, G., Garciá-Closas, M., Antoniou, A.C., Simard, J., Nature Genetics, 2017, 10.1038/ng.3785
Influence of a pre-stimulation with chronic low-dose UVB on stress response mechanisms in human skin fibroblasts, Desgarnier, M.-C.D., Fournier, F., Droit, A., Rochette, P.J., PLoS ONE, 2017, 10.1371/journal.pone.0173740
Specific expression of novel long non-coding RNAs in high-hyperdiploid childhood acute lymphoblastic leukemia, Lajoie, M., Drouin, S., Caron, M., St-Onge, P., Ouimet, M., Gioia, R., Lafond, M.-H., Vidal, R., Richer, C., Oualkacha, K., Droit, A., Sinnett, D., PLoS ONE, 2017, 10.1371/journal.pone.0174124
Transcriptional signature of lymphoblastoid cell lines of BRCA1, BRCA2 and non-BRCA1/2 high risk breast cancer families, Pouliot, M.-C., Kothari, C., Joly-Beauparlant, C., Labrie, Y., Ouellette, G., Simard, J., Droit, A., Durocher, F., Oncotarget, 2017, 10.18632/oncotarget.20219
Triggering of NOD2 Receptor Converts Inflammatory Ly6C^high into Ly6C^low Monocytes with Patrolling Properties, Lessard, A.-J., LeBel, M., Egarnes, B., Préfontaine, P., Thériault, P., Droit, A., Brunet, A., Rivest, S., Gosselin, J., Cell Reports, 2017, 10.1016/j.celrep.2017.08.009
VEXOR: An integrative environment for prioritization of functional variants in fine-mapping analysis, Lemaçon, A., Beauparlant, C.J., Soucy, P., Allen, J., Easton, D., Kraft, P., Simard, J., Droit, A., Bioinformatics, 2017, 10.1093/bioinformatics/btw826
Analysis of the translatome in solid tumors using polyribosome profiling/RNA-Seq, Pauline Adjibade, Valerie Grenier St-Sauveur, Arnaud Droit, Edouard W. Khandjian, Paul Toren, Rachid Mazroui, Journal of Biological Methods, 2016, 10.14440/jbm.2016.151
A metabolic labeling approach for glycoproteomic analysis reveals altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells, Sheta, R., Woo, C.M., Roux-Dalvai, F., Fournier, F., Bourassa, S., Droit, A., Bertozzi, C.R., Bachvarov, D., Journal of Proteomics, 2016, 10.1016/j.jprot.2016.04.009
Association of breast cancer risk with genetic variants showing differential allelic expression: Identification of a novel breast cancer susceptibility locus at 4q21, Hamdi, Y., Soucy, P., Adoue, V., Michailidou, K., Canisius, S., Lemaçon, A., Droit, A., Andrulis, I.L., Anton-Culver, H., Arndt, V., Baynes, C., Blomqvist, C., Bogdanova, N.V., Bojesen, S.E., Bolla, M.K., Bonanni, B., Borresen-Dale, A.-L., Brand, J.S., Brauch, H., Brenner, H., Broeks, A., Burwinkel, B., Chang-Claude, J., Couch, F.J., Cox, A., Cross, S.S., Czene, K., Darabi, H., Dennis, J., Devilee, P., Dörk, T., Dos-Santos-Silva, I., Eriksson, M., Fasching, P.A., Figueroa, J., Flyger, H., García-Closas, M., Giles, G.G., Goldberg, M.S., González-Neira, A., Grenaker-Alnæs, G., Guénel, P., Haeberle, L., Haiman, C.A., Hamann, U., Hallberg, E., Hooning, M.J., Hopper, J.L., Jakubowska, A., Jones, M., Kabisch, M., Kataja, V., Lambrechts, D., Le Marchand, L., Lindblom, A., Lubinski, J., Mannermaa, A., Maranian, M., Margolin, S., Marme, F., Milne, R.L., Neuhausen, S.L., Nevanlinna, H., Neven, P., Olswold, C., Peto, J., Plaseska-Karanfilska, D., Pylkäs, K., Radice, P., Rudolph, A., Sawyer, E.J., Schmidt, M.K., Shu, X.-O., Southey, M.C., Swerdlow, A., Tollenaar, R.A.E.M., Tomlinson, I., Torres, D., Truong, T., Vachon, C., Van Den Ouweland, A.M.W., Wang, Q., Winqvist, R., Zheng, W., Benitez, J., Chenevix-Trench, G., Dunning, A.M., Pharoah, P.D.P., Kristensen, V., Hall, P., Easton, D.F., Pastinen, T., Nord, S., Simard, J., Oncotarget, 2016, 10.18632/oncotarget.12818
Divergent Expression and Metabolic Functions of Human Glucuronosyltransferases through Alternative Splicing, Rouleau, M., Tourancheau, A., Girard-Bock, C., Villeneuve, L., Vaucher, J., Duperré, A.-M., Audet-Delage, Y., Gilbert, I., Popa, I., Droit, A., Guillemette, C., Cell Reports, 2016, 10.1016/j.celrep.2016.08.077
Effects of long-term serial passaging on the characteristics and properties of cell lines derived from uveal melanoma primary tumors, Mouriaux, F., Zaniolo, K., Bergeron, M.-A., Weidmann, C., De La Fouchardière, A., Fournier, F., Droit, A., Morcos, M.W., Landreville, S., Guérin, S.L., Investigative Ophthalmology and Visual Science, 2016, 10.1167/iovs.16-19317
Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs), Darabi, H., Beesley, J., Droit, A., Kar, S., Nord, S., Marjaneh, M.M., Soucy, P., Michailidou, K., Ghoussaini, M., Wahl, H.F., Bolla, M.K., Wang, Q., Dennis, J., Alonso, M.R., Andrulis, I.L., Anton-Culver, H., Arndt, V., Beckmann, M.W., Benitez, J., Bogdanova, N.V., Bojesen, S.E., Brauch, H., Brenner, H., Broeks, A., Brüning, T., Burwinkel, B., Chang-Claude, J., Choi, J.-Y., Conroy, D.M., Couch, F.J., Cox, A., Cross, S.S., Czene, K., Devilee, P., Dörk, T., Easton, D.F., Fasching, P.A., Figueroa, J., Fletcher, O., Flyger, H., Galle, E., García-Closas, M., Giles, G.G., Goldberg, M.S., González-Neira, A., Guénel, P., Haiman, C.A., Hallberg, E., Hamann, U., Hartman, M., Hollestelle, A., Hopper, J.L., Ito, H., Jakubowska, A., Johnson, N., Kang, D., Khan, S., Kosma, V.-M., Kriege, M., Kristensen, V., Lambrechts, D., Le Marchand, L., Lee, S.C., Lindblom, A., Lophatananon, A., Lubinski, J., Mannermaa, A., Manoukian, S., Margolin, S., Matsuo, K., Mayes, R., McKay, J., Meindl, A., Milne, R.L., Muir, K., Neuhausen, S.L., Nevanlinna, H., Olswold, C., Orr, N., Peterlongo, P., Pita, G., Pylkäs, K., Rudolph, A., Sangrajrang, S., Sawyer, E.J., Schmidt, M.K., Schmutzler, R.K., Seynaeve, C., Shah, M., Shen, C.-Y., Shu, X.-O., Southey, M.C., Stram, D.O., Surowy, H., Swerdlow, A., Teo, S.H., Tessier, D.C., Tomlinson, I., Torres, D., Truong, T., Vachon, C.M., Vincent, D., Winqvist, R., Wu, A.H., Wu, P.-E., Yip, C.H., Zheng, W., Pharoah, P.D.P., Hall, P., Edwards, S.L., Simard, J., French, J.D., Chenevix-Trench, G., Dunning, A.M., Scientific Reports, 2016, 10.1038/srep32512
Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer, Shi, J., Zhang, Y., Zheng, W., Michailidou, K., Ghoussaini, M., Bolla, M.K., Wang, Q., Dennis, J., Lush, M., Milne, R.L., Shu, X.-O., Beesley, J., Kar, S., Andrulis, I.L., Anton-Culver, H., Arndt, V., Beckmann, M.W., Zhao, Z., Guo, X., Benitez, J., Beeghly-Fadiel, A., Blot, W., Bogdanova, N.V., Bojesen, S.E., Brauch, H., Brenner, H., Brinton, L., Broeks, A., Brüning, T., Burwinkel, B., Cai, H., Canisius, S., Chang-Claude, J., Choi, J.-Y., Couch, F.J., Cox, A., Cross, S.S., Czene, K., Darabi, H., Devilee, P., Droit, A., Dork, T., Fasching, P.A., Fletcher, O., Flyger, H., Fostira, F., Gaborieau, V., García-Closas, M., Giles, G.G., Grip, M., Guenel, P., Haiman, C.A., Hamann, U., Hartman, M., Miao, H., Hollestelle, A., Hopper, J.L., Hsiung, C.-N., Ito, H., Jakubowska, A., Johnson, N., Torres, D., Kabisch, M., Kang, D., Khan, S., Knight, J.A., Kosma, V.-M., Lambrechts, D., Li, J., Lindblom, A., Lophatananon, A., Lubinski, J., Mannermaa, A., Manoukian, S., Le Marchand, L., Margolin, S., Marme, F., Matsuo, K., McLean, C., Meindl, A., Muir, K., Neuhausen, S.L., Nevanlinna, H., Nord, S., Børresen-Dale, A.-L., Olson, J.E., Orr, N., van den Ouweland, A.M.W., Peterlongo, P., Choudary Putti, T., Rudolph, A., Sangrajrang, S., Sawyer, E.J., Schmidt, M.K., Schmutzler, R.K., Shen, C.-Y., Hou, M.-F., Shrubsole, M.J., Southey, M.C., Swerdlow, A., Hwang Teo, S., Thienpont, B., Toland, A.E., Tollenaar, R.A.E.M., Tomlinson, I., Truong, T., Tseng, C.-C., Wen, W., Winqvist, R., Wu, A.H., Har Yip, C., Zamora, P.M., Zheng, Y., Floris, G., Cheng, C.-Y., Hooning, M.J., Martens, J.W.M., Seynaeve, C., Kristensen, V.N., Hall, P., Pharoah, P.D.P., Simard, J., Chenevix-Trench, G., Dunning, A.M., Antoniou, A.C., Easton, D.F., Cai, Q., Long, J., International Journal of Cancer, 2016, 10.1002/ijc.30150
FOXA and master transcription factors recruit Mediator and Cohesin to the core transcriptional regulatory circuitry of cancer cells, Fournier, M., Bourriquen, G., Lamaze, F.C., Côté, M.C., Fournier, É., Joly-Beauparlant, C., Caron, V., Gobeil, S., Droit, A., Bilodeau, S., Scientific Reports, 2016, 10.1038/srep34962
Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus, Zeng, C., Guo, X., Long, J., Kuchenbaecker, K.B., Droit, A., Michailidou, K., Ghoussaini, M., Kar, S., Freeman, A., Hopper, J.L., Milne, R.L., Bolla, M.K., Wang, Q., Dennis, J., Agata, S., Ahmed, S., Aittomäki, K., Andrulis, I.L., Anton-Culver, H., Antonenkova, N.N., Arason, A., Arndt, V., Arun, B.K., Arver, B., Bacot, F., Barrowdale, D., Baynes, C., Beeghly-Fadiel, A., Benitez, J., Bermisheva, M., Blomqvist, C., Blot, W.J., Bogdanova, N.V., Bojesen, S.E., Bonanni, B., Borresen-Dale, A.-L., Brand, J.S., Brauch, H., Brennan, P., Brenner, H., Broeks, A., Brüning, T., Burwinkel, B., Buys, S.S., Cai, Q., Caldes, T., Campbell, I., Carpenter, J., Chang-Claude, J., Choi, J.-Y., Claes, K.B.M., Clarke, C., Cox, A., Cross, S.S., Czene, K., Daly, M.B., de la Hoya, M., De Leeneer, K., Devilee, P., Diez, O., Domchek, S.M., Doody, M., Dorfling, C.M., Dörk, T., dos-Santos-Silva, I., Dumont, M., Dwek, M., Dworniczak, B., Egan, K., Eilber, U., Einbeigi, Z., Ejlertsen, B., Ellis, S., Frost, D., Lalloo, F., Fasching, P.A., Figueroa, J., Flyger, H., Friedlander, M., Friedman, E., Gambino, G., Gao, Y.-T., Garber, J., García-Closas, M., Gehrig, A., Damiola, F., Lesueur, F., Mazoyer, S., Stoppa-Lyonnet, D., Giles, G.G., Godwin, A.K., Goldgar, D.E., González-Neira, A., Greene, M.H., Guénel, P., Haeberle, L., Haiman, C.A., Hallberg, E., Hamann, U., Hansen, T.V.O., Hart, S., Hartikainen, J.M., Hartman, M., Hassan, N., Healey, S., Hogervorst, F.B.L., Verhoef, S., Hendricks, C.B., Hillemanns, P., Hollestelle, A., Hulick, P.J., Hunter, D.J., Imyanitov, E.N., Isaacs, C., Ito, H., Jakubowska, A., Janavicius, R., Jaworska-Bieniek, K., Jensen, U.B., John, E.M., Joly Beauparlant, C., Jones, M., Kabisch, M., Kang, D., Karlan, B.Y., Kauppila, S., Kerin, M.J., Khan, S., Khusnutdinova, E., Knight, J.A., Konstantopoulou, I., Kraft, P., Kwong, A., Laitman, Y., Lambrechts, D., Lazaro, C., Le Marchand, L., Lee, C.N., Lee, M.H., Lester, J., Li, J., Liljegren, A., Lindblom, A., Lophatananon, A., Lubinski, J., Mai, P.L., Mannermaa, A., Manoukian, S., Margolin, S., Marme, F., Matsuo, K., McGuffog, L., Meindl, A., Menegaux, F., Montagna, M., Muir, K., Mulligan, A.M., Nathanson, K.L., Neuhausen, S.L., Nevanlinna, H., Newcomb, P.A., Nord, S., Nussbaum, R.L., Offit, K., Olah, E., Olopade, O.I., Olswold, C., Osorio, A., Papi, L., Park-Simon, T.-W., Paulsson-Karlsson, Y., Peeters, S., Peissel, B., Peterlongo, P., Peto, J., Pfeiler, G., Phelan, C.M., Presneau, N., Radice, P., Rahman, N., Ramus, S.J., Rashid, M.U., Rennert, G., Rhiem, K., Rudolph, A., Salani, R., Sangrajrang, S., Sawyer, E.J., Schmidt, M.K., Schmutzler, R.K., Schoemaker, M.J., Schürmann, P., Seynaeve, C., Shen, C.-Y., Shrubsole, M.J., Shu, X.-O., Sigurdson, A., Singer, C.F., Slager, S., Soucy, P., Southey, M., Steinemann, D., Swerdlow, A., Szabo, C.I., Tchatchou, S., Teixeira, M.R., Teo, S.H., Terry, M.B., Tessier, D.C., Teulé, A., Thomassen, M., Tihomirova, L., Tischkowitz, M., Toland, A.E., Tung, N., Turnbull, C., van den Ouweland, A.M.W., van Rensburg, E.J., ven den Berg, D., Vijai, J., Wang-Gohrke, S., Weitzel, J.N., Whittemore, A.S., Winqvist, R., Wong, T.Y., Wu, A.H., Yannoukakos, D., Yu, J.-C., Pharoah, P.D.P., Hall, P., Chenevix-Trench, G., Dunning, A.M., Simard, J., Couch, F.J., Antoniou, A.C., Easton, D.F., Zheng, W., Breast Cancer Research, 2016, 10.1186/s13058-016-0718-0
iTRAQ-based quantitative proteomics of stratum corneum of dandruff scalp reveals new insights into its aetiology and similarities with atopic dermatitis, Cavusoglu, N., Delattre, C., Donovan, M., Bourassa, S., Droit, A., El Rawadi, C., Jourdain, R., Bernard, D., Archives of Dermatological Research, 2016, 10.1007/s00403-016-1681-4
metagene Profiles Analyses Reveal Regulatory Element’s Factor-Specific Recruitment Patterns, Joly Beauparlant, C., Lamaze, F.C., Deschênes, A., Samb, R., Lemaçon, A., Belleau, P., Bilodeau, S., Droit, A., PLoS Computational Biology, 2016, 10.1371/journal.pcbi.1004751
MicroRNA-132/212 deficiency enhances Aβ production and senile plaque deposition in Alzheimer's disease triple transgenic mice, Hernandez-Rapp, J., Rainone, S., Goupil, C., Dorval, V., Smith, P.Y., Saint-Pierre, M., Vallée, M., Planel, E., Droit, A., Calon, F., Cicchetti, F., Hébert, S.S., Scientific Reports, 2016, 10.1038/srep30953
Neutrophil-derived exosomes: A new mechanism contributing to airway smooth muscle remodeling, Vargas, A., Roux-Dalvai, F., Droit, A., Lavoie, J.-P., American Journal of Respiratory Cell and Molecular Biology, 2016, 10.1165/rcmb.2016-0033OC
Proteomic dataset for altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells, Sheta, R., Roux-Dalvai, F., Woo, C.M., Fournier, F., Bourassa, S., Bertozzi, C.R., Droit, A., Bachvarov, D., Data in Brief, 2016, 10.1016/j.dib.2016.05.060
RNA expression profile of calcified bicuspid, tricuspid, and normal human aortic valves by RNA sequencing, Guauque-Olarte, S., Droit, A., Tremblay-Marchand, J., Gaudreault, N., Kalavrouziotis, D., Dagenais, F., Seidman, J.G., Body, S.C., Pibarot, P., Mathieu, P., Bossé, Y., Physiological Genomics, 2016, 10.1152/physiolgenomics.00041.2016
Selective and sensitive quantification of the cytochrome P450 3A4 protein in human liver homogenates through multiple reaction monitoring mass spectrometry, Cieślak, A., Kelly, I., Trottier, J., Verreault, M., Wunsch, E., Milkiewicz, P., Poirier, G., Droit, A., Barbier, O., Proteomics, 2016, 10.1002/pmic.201500386
Unravelling the transcriptomic landscape of the major phase II UDP-glucuronosyltransferase drug metabolizing pathway using targeted RNA sequencing, Tourancheau, A., Margaillan, G., Rouleau, M., Gilbert, I., Villeneuve, L., Lévesque, E., Droit, A., Guillemette, C., Pharmacogenomics Journal, 2016, 10.1038/tpj.2015.20
Calcium Signaling Pathway Genes RUNX2 and CACNA1C Are Associated with Calcific Aortic Valve Disease, Guauque-Olarte, S., Messika-Zeitoun, D., Droit, A., Lamontagne, M., Tremblay-Marchand, J., Lavoie-Charland, E., Gaudreault, N., Arsenault, B.J., Dube, M.-P., Tardif, J.-C., Body, S.C., Seidman, J.G., Boileau, C., Mathieu, P., Pibarot, P., Bosse, Y., Circulation: Cardiovascular Genetics, 2015, 10.1161/CIRCGENETICS.115.001145
Evaluation of iTRAQ and SWATH-MS for the quantification of proteins associated with insulin resistance in human duodenal biopsy samples, Bourassa, S., Fournier, F., Nehmé, B., Kelly, I., Tremblay, A., Lemelin, V., Lamarche, B., Couture, P., Droit, A., PLoS ONE, 2015, 10.1371/journal.pone.0125934
Fine-scale mapping of the 4q24 locus identifies & pr two Independent loci associated with breast cancer risk, Guo, X., Long, J., Zeng, C., Michailidou, K., Ghoussaini, M., Bolla, M.K., Wang, Q., Milne, R.L., Shu, X.-O., Cai, Q., Beesley, J., Kar, S.P., Andrulis, I.L., Anton-Culver, H., Arndt, V., Beckmann, M.W., Beeghly-Fadiel, A., Benitez, J., Blot, W., Bogdanova, N., Bojesen, S.E., Brauch, H., Brenner, H., Brinton, L., Broekss, A., Bruning, T., Burwinkel, B., Cai, H., Canisius, S., Chang-Claude, J., Choi, J.-Y., Couch, F.J., Cox, A., Cross, S.S., Czene, K., Darabi, H., Devilee, P., Droit, A., Dork, T., Fasching, P.A., Fletcher, O., Flyger, H., Fostira, F., Gaborieau, V., García-Closas, M., Giles, G.G., Grip, M., Guenel, P., Haiman, C.A., Hamann, U., Hartman, M., Hollestelle, A., Hopper, J.L., Hsiung, C.-N., Ito, H., Jakubowska, A., Johnson, N., Kabisch, M., Kang, D., Khan, S., Knight, J.A., Kosma, V.-M., Lambrechts, D., Le Marchand, L., Li, J., Lindblom, A., Lophatananon, A., Lubinski, J., Mannermaa, A., Manoukian, S., Margolin, S., Marme, F., Matsuo, K., McLean, C.A., Meindl, A., Muir, K., Neuhausen, S.L., Nevanlinna, H., Nord, S., Olson, J.E., Orr, N., Peterlongo, P., Putti, T.C., Rudolph, A., Sangrajrang, S., Sawyer, E.J., Schmidt, M.K., Schmutzler, R.K., Shen, C.-Y., Shi, J., Shrubsole, M.J., Southey, M.C., Swerdlow, A., Teo, S.H., Thienpont, B., Toland, A.E., Tollenaar, R.A.E.M., Tomlinson, I.P.M., Truong, T., Tseng, C.-C., Van Den Ouweland, A., Wen, W., Winqvist, R., Wu, A., Yip, C.H., Zamora, M.P., Zheng, Y., Hall, P., Pharoah, P.D.P., Simard, J., Chenevix-Trench, G., Dunning, A.M., Easton, D.F., Zheng, W., Eeles, R.A., Al Olama, A.A., Kote-Jarai, Z., Benlloch, S., Antoniou, A., McGuffog, L., Offit, K., Lee, A., Dicks, E., Luccarini, C., Tessier, D.C., Bacot, F., Vincent, D., La Boissière, S., Robidoux, F., Nielsen, S.F., Cunningham, J.M., Windebank, S.A., Hilker, C.A., Meyer, J., Angelakos, M., Maskiell, J., Van Der Schoot, E., Rutgers, E., Verhoef, S., Hogervorst, F., Boonyawongviroj, P., Siriwanarungsan, P., Schrauder, M., Rübner, M., Oeser, S., Landrith, S., Williams, E., Ryder-Mills, E., Sargus, K., McInerney, N., Colleran, G., Rowan, A., Jones, A., Sohn, C., Schneeweiß, A., Bugert, P., Álvarez, N., Bernstein, L., Lacey, J., Wang, S., Ma, H., Lu, Y., Clague De Hart, J., Deapen, D., Pinder, R., Lee, E., Schumacher, F., Horn-Ross, P., Reynolds, P., Nelson, D., Park, H., Ziegler, H., Wolf, S., Hermann, V., Lo, W.-Y., Justenhoven, C., Ko, Y.-D., Baisch, C., Fischer, H.-P., Pesch, B., Rabstein, S., Lotz, A., Harth, V., Heikkinen, T., Erkkilä, I., Aaltonen, K., Von Smitten, K., Antonenkova, N., Hillemanns, P., Christiansen, H., Myöhänen, E., Kemiläinen, H., Thorne, H., Niedermayr, E., Bowtell, D., De Fazio, A., Gertig, D., Green, A., Webb, P., Green, A., Parsons, P., Hayward, N., Whiteman, D., Fung, A., Yashiki, J., Peuteman, G., Smeets, D., Van Brussel, T., Corthouts, K., Obi, N., Heinz, J., Behrens, S., Eilber, U., Celik, M., Olchers, T., Peissel, B., Scuvera, G., Zaffaroni, D., Bonanni, B., Feroce, I., Maniscalco, A., Rossi, A., Bernard, L., Tranchant, M., Valois, M.-F., Turgeon, A., Heguy, L., Yee, P.S., Kang, P., Nee, K.I., Mariapun, S., Sook-Yee, Y., Lee, D., Ching, T.Y., Taib, N.A.M., Otsukka, M., Mononen, K., Selander, T., Weerasooriya, N., Krol-Warmerdam, E., Molenaar, J., Blom, J., Szeszenia-Dabrowska, N., Peplonska, B., Zatonski, W., Chao, P., Stagner, M., Bos, P., Crepin, E., Nieuwlaat, A., Heemskerk, A., Higham, S., Cramp, H., Connley, D., Balasubramanian, S., Brock, I., Kerin, M., Miller, N., Kerbrat, P., Arveux, P., Le Scodan, R., Raoul, Y., Laurent-Puig, P., Mulot, C., Stegmaier, C., Butterbach, K., Karstens, J.H., Flesch-Janys, D., Seibold, P., Vrieling, A., Nickels, S., Radice, P., Pylkäs, K., Jukkola-Vuorinen, A., Kauppila, S., Conroy, D., Baynes, C., Chua, K., Pilarski, R., Cancer Epidemiology Biomarkers and Prevention, 2015, 10.1158/1055-9965.EPI-15-0363
Implementation and Evaluation of a Wiki Involving Multiple Stakeholders Including Patients in the Promotion of Best Practices in Trauma Care: The WikiTrauma, , JMIR Research Protocols, 2015, 10.2196/resprot.4024
Quantitative site-specific ADP-ribosylation profiling of DNA-dependent PARPs, Gagné, J.-P., Ethier, C., Defoy, D., Bourassa, S., Langelier, M.-F., Riccio, A.A., Pascal, J.M., Moon, K.-M., Foster, L.J., Ning, Z., Figeys, D., Droit, A., Poirier, G.G., DNA Repair, 2015, 10.1016/j.dnarep.2015.02.004
Skeletal muscle proteomic signature and metabolic impairment in pulmonary hypertension, Malenfant, S., Potus, F., Fournier, F., Breuils-Bonnet, S., Pflieger, A., Bourassa, S., Tremblay, È., Nehmé, B., Droit, A., Bonnet, S., Provencher, S., Journal of Molecular Medicine, 2015, 10.1007/s00109-014-1244-0
Using informative Multinomial-Dirichlet prior in a t-mixture with reversible jump estimation of nucleosome positions for genome-wide profiling, Samb, R., Khadraoui, K., Belleau, P., Deschênes, A., Lakhal-Chaieb, L., Droit, A., Statistical Applications in Genetics and Molecular Biology, 2015, 10.1515/sagmb-2014-0098
Bio2RDF release 3: A larger connected network of linked data for the life sciences, Dumontier, M., Callahan, A., Cruz-Toledo, J., Ansell, P., Emonet, V., Belleau, F., Droit, A., CEUR Workshop Proceedings, 2014
Effect of an isoenergetic traditional mediterranean diet on the high-density lipoprotein proteome in men with the metabolic syndrome, Richard, C., Couture, P., Desroches, S., Nehmé, B., Bourassa, S., Droit, A., Lamarche, B., Journal of Nutrigenetics and Nutrigenomics, 2014, 10.1159/000363137
Effect of sitagliptin therapy on triglyceride-rich lipoprotein kinetics in patients with type 2 diabetes, Tremblay, A.J., Lamarche, B., Kelly, I., Charest, A., Lépine, M.-C., Droit, A., Couture, P., Diabetes, Obesity and Metabolism, 2014, 10.1111/dom.12359
Establishment of a comprehensive reference transcriptome for vertebral bone tissue to study the impacts of nutritional phosphorus deficiency in rainbow trout (Oncorhynchus mykiss, Walbaum), Le Luyer, J., Deschamps, M.-H., Proulx, E., Poirier Stewart, N., Joly Beauparlant, C., Droit, A., Robert, C., Vandenberg, G.W., Marine Genomics, 2014, 10.1016/j.margen.2014.10.002
Investigation of male infertility using quantitative comparative proteomics, Légaré, C., Droit, A., Fournier, F., Bourassa, S., Force, A., Cloutier, F., Tremblay, R., Sullivan, R., Journal of Proteome Research, 2014, 10.1021/pr501031x
Key intestinal genes involved in lipoprotein metabolism are downregulated in dyslipidemic men with insulin resistance, Couture, P., Tremblay, A.J., Kelly, I., Lemelin, V., Droit, A., Lamarche, B., Journal of Lipid Research, 2014, 10.1194/jlr.M040071
Quantitative proteomic analysis of amphotericin B resistance in Leishmania infantum, Brotherton, M.-C., Bourassa, S., Légaré, D., Poirier, G.G., Droit, A., Ouellette, M., International Journal for Parasitology: Drugs and Drug Resistance, 2014, 10.1016/j.ijpddr.2014.05.002
RTANDEM, an R/Bioconductor package for MS/MS protein identification, Fournier, F., Joly Beauparlant, C., Paradis, R., Droit, A., Bioinformatics, 2014, 10.1093/bioinformatics/btu178
Integration of high-resolution methylome and transcriptome analyses to dissect epigenomic changes in childhood acute lymphoblastic leukemia, Busche, S., Ge, B., Vidal, R., Spinella, J.-F., Saillour, V., Richer, C., Healy, J., Chen, S.-H., Droit, A., Sinnett, D., Pastinen, T., Cancer Research, 2013, 10.1158/0008-5472.CAN-12-4367
NGS++: A library for rapid prototyping of epigenomics software tools, Markovits, A.N., Beauparlant, C.J., Toupin, D., Wang, S., Droit, A., Gevry, N., Bioinformatics, 2013, 10.1093/bioinformatics/btt312
Proteomic and genomic analyses of antimony resistant Leishmania infantum mutant, Brotherton, M.-C., Bourassa, S., Leprohon, P., Légaré, D., Poirier, G.G., Droit, A., Ouellette, M., PLoS ONE, 2013, 10.1371/journal.pone.0081899
An integrated pipeline for the genome-wide analysis of transcription factor binding sites from ChiP-Seq, Mercier, E., Droit, A., Li, L., Robertson, G., Zhang, X., Gottardo, R., PLoS ONE, 2011, 10.1371/journal.pone.0016432
PICS: Probabilistic Inference for ChIP-seq, Zhang, X., Robertson, G., Krzywinski, M., Ning, K., Droit, A., Jones, S., Gottardo, R., Biometrics, 2011, 10.1111/j.1541-0420.2010.01441.x
rMAT - An R/Bioconductor package for analyzing ChIP-chip experiments, Droit, A., Cheung, C., Gottardo, R., Bioinformatics, 2010, 10.1093/bioinformatics/btq023
Proteomic investigation of phosphorylation sites in poly(ADP-ribose) polymerase-1 and poly(ADP-ribose) glycohydrolase, Gagné, J.-P., Moreel, X., Gagné, P., Labelle, Y., Droit, A., Chevalier-Paré, M., Bourassa, S., McDonald, D., Hendzel, M.J., Prigent, C., Poirier, G.G., Journal of Proteome Research, 2009, 10.1021/pr800810n
Human Proteinpedia enables sharing of human protein data [4], Mathivanan, S., Ahmed, M., Ahn, N.G., Alexandre, H., Amanchy, R., Andrews, P.C., Bader, J.S., Balgley, B.M., Bantscheff, M., Bennett, K.L., Björling, E., Blagoev, B., Bose, R., Brahmachari, S.K., Burlingame, A.S., Bustelo, X.R., Cagney, G., Cantin, G.T., Cardasis, H.L., Celis, J.E., Chaerkady, R., Chu, F., Cole, P.A., Costello, C.E., Cotter, R.J., Crockett, D., DeLany, J.P., De Marzo, A.M., DeSouza, L.V., Deutsch, E.W., Dransfield, E., Drewes, G., Droit, A., Dunn, M.J., Elenitoba-Johnson, K., Ewing, R.M., Eyk, J.V., Faca, V., Falkner, J., Fang, X., Fenselau, C., Figeys, D., Gagné, P., Gelfi, C., Gevaert, K., Gimble, J.M., Gnad, F., Goel, R., Gromov, P., Hanash, S.M., Hancock, W.S., Harsha, H.C., Hart, G., Hays, F., He, F., Hebbar, P., Helsens, K., Hermeking, H., Hide, W., Hjernø, K., Hochstrasser, D.F., Hofmann, O., Horn, D.M., Hruban, R.H., Ibarrola, N., James, P., Jensen, O.N., Jensen, P.H., Jung, P., Kandasamy, K., Kheterpal, I., Kikuno, R.F., Korf, U., Körner, R., Kuster, B., Kwon, M.-S., Lee, H.-J., Lee, Y.-J., Lefevre, M., Lehvaslaiho, M., Lescuyer, P., Levander, F., Lim, M.S., Löbke, C., Loo, J.A., Mann, M., Martens, L., Martinez-Heredia, J., McComb, M., McRedmond, J., Mehrle, A., Menon, R., Miller, C.A., Mischak, H., Mohan, S.S., Mohmood, R., Molina, H., Moran, M.F., Morgan, J.D., Moritz, R., Morzel, M., Muddiman, D.C., Nalli, A., Navarro, J.D., Neubert, T.A., Ohara, O., Oliva, R., Omenn, G.S., Oyama, M., Paik, Y.-K., Pennington, K., Pepperkok, R., Periaswamy, B., Petricoin, E.F., Poirier, G.G., Prasad, T.S.K., Purvine, S.O., Rahiman, B.A., Ramachandran, P., Ramachandra, Y.L., Rice, R.H., Rick, J., Ronnholm, R.H., Salonen, J., Sanchez, J.-C., Sayd, T., Seshi, B., Shankari, K., Sheng, S.J., Shetty, V., Shivakumar, K., Simpson, R.J., Sirdeshmukh, R., Michael Siu, K.W., Smith, J.C., Smith, R.D., States, D.J., Sugano, S., Sullivan, M., Superti-Furga, G., Takatalo, M., Thongboonkerd, V., Trinidad, J.C., Uhlen, M., Vandekerckhove, J., Vasilescu, J., Veenstra, T.D., Vidal-Taboada, J.-M., Vihinen, M., Wait, R., Wang, X., Wiemann, S., Wu, B., Xu, T., Yates, J.R., Zhong, J., Zhou, M., Zhu, Y., Zurbig, P., Pandey, A., Nature Biotechnology, 2008, 10.1038/nbt0208-164
Quality assessment of peptide tandem mass spectra, Wu, F.-X., Gagné, P., Droit, A., Poirier, G.G., BMC Bioinformatics, 2008, 10.1186/1471-2105-9-S6-S13
Comparative proteome analysis of human epithelial ovarian cancer, Gagné, J.-P., Éthier, C., Gagné, P., Mercier, G., Bonicalzi, M.-E., Mes-Masson, A.-M., Droit, A., Winstall, E., Isabelle, M., Poirier, G.G., Proteome Science, 2007, 10.1186/1477-5956-5-16
PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery, Rouleau, M., McDonald, D., Gagné, P., Ouellet, M.-E., Droit, A., Hunter, J.M., Dutertre, S., Prigent, C., Hendzel, M.J., Poirier, G.G., Journal of Cellular Biochemistry, 2007, 10.1002/jcb.21051
PARPs database: A LIMS systems for protein-protein interaction data mining or laboratory information management system, Droit, A., Hunter, J.M., Rouleau, M., Ethier, C., Picard-Cloutier, A., Bourgais, D., Poirier, G.G., BMC Bioinformatics, 2007, 10.1186/1471-2105-8-483
Bioinformatic standards for proteomics-oriented mass spectrometry, Droit, A., Fillon, J., Morissette, J., Poirier, G.G., Current Proteomics, 2006, 10.2174/157016406778194617
Quality assessment of peptide tandem mass spectra, Wu, F.-X., Gagné, P., Droit, A., Poirier, G.G., First International Multi- Symposiums on Computer and Computational Sciences, IMSCCS'06, 2006, 10.1109/IMSCCS.2006.109
RT-PSM, a real-time program for peptide-spectrum matching with statistical significance, Wu, F.-X., Gagné, P., Droit, A., Poirier, G.G., Rapid Communications in Mass Spectrometry, 2006, 10.1002/rcm.2435
The expanding role of poly(ADP-ribose) metabolism: Current challenges and new perspectives, Gagné, J.-P., Hendzel, M.J., Droit, A., Poirier, G.G., Current Opinion in Cell Biology, 2006, 10.1016/j.ceb.2006.02.013
Experimental and bioinformatic approaches for interrogating protein-protein interactions to determine protein function, Droit, A., Poirier, G.G., Hunter, J.M., Journal of Molecular Endocrinology, 2005, 10.1677/jme.1.01693
Proteome profiling of human epithelial ovarian cancer cell line TOV-112D, Gagné, J.-P., Gagné, P., Hunter, J.M., Bonicalzi, M.-È., Lemay, J.-F., Kelly, I., Le Page, C., Provencher, D., Mes-Masson, A.-M., Droit, A., Bourgais, D., Poirier, G.G., Molecular and Cellular Biochemistry, 2005, 10.1007/s11010-005-7556-1
Regulation of poly(ADP-ribose) metabolism by poly(ADP-ribose) glycohydrolase: Where and when?, Bonicalzi, M.-E., Haince, J.-F., Droit, A., Poirier, G.G., Cellular and Molecular Life Sciences, 2005, 10.1007/s00018-004-4505-1

...

Contribution à l'enseignement aux cycles supérieurs

Étudiant(e)s dirigé(e)s*

Depuis 2009

Alexandra Carrier - Doctorat - En cours
Khawla Seddiki - Doctorat - En cours
Kodjovi Dodji Mlaga - Post-doctorat - En cours
Camille Cassandre Illiano - Doctorat - En cours
Virgile Raufaste-Cazavieille - Doctorat - En cours
Elloise Coyle - Doctorat - En cours
Sophiane Bouirdene - Doctorat - En cours
Antoine Lacombe - Maitrîse avec mémoire - En cours
Elsa Claude - Doctorat - En cours
Vivian Robin - Doctorat - En cours
Louis Ohl - Doctorat - En cours
Steven Boutrais - Doctorat - En cours
Paul-Emmanuel Edeline - Doctorat - En cours
Mélissande Nagati - Post-doctorat - En cours
Milan Picard - Doctorat - En cours
El Hadji Ousseynou Accrachi - Doctorat - En cours
Andréanne Gagné - Doctorat - En cours
Loïc Mangnier - Doctorat - En cours
Simon Gotty - Maitrîse avec mémoire - En cours
Tania Isabelle Lalia Cuppens - Post-doctorat - En cours
Jean-Paul Navailles - Doctorat - En cours
Olivia Gavard - Doctorat - En cours
Samarth Thonta Setty - Post-doctorat - En cours
Alan Tourancheau - Doctorat - 2016/01
Jean-Sébastien Milanese - Maitrîse avec mémoire - 2017/09
Audrey Lemaçon - Doctorat - 2019/01
Benjamin Vittrant - Doctorat - 2021/01
Louis Cossus - Doctorat - 2021/05
Antoine Bodein - Doctorat - 2021/05
Roxanne Sergerie - Maitrîse avec mémoire - 2022/01
Régis Ongaro-Carcy - Doctorat - 2022/05

Encadrement d'étudiant(e)s pour les programmes suivants :

Médecine moléculaire

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*Les supervisions d’étudiant(e)s de 1er cycle en stage de recherche et de résident(e)s aux études médicales postdoctorales seront répertoriées ultérieurement.

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